cranial nerve palsy: Injury to any of the cranial nerves or their nuclei in the brain resulting in muscle weakness.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
702 |
4. Check minimum number of eventsNone |
702 |
5. Include endpointsNone |
702 |
6. Filter based on genotype QC (FinnGen only) |
608 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Postzoster neuralgia
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3542 | 2189 | 1325 |
| Only index persons | 3234 | 2038 | 1196 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 75.27 | 76.62 | 72.99 |
| Only index persons | 74.95 | 76.35 | 72.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 608 | 361 | 247 |
| Unadjusted period prevalence (%) | 0.12 | 0.13 | 0.11 |
| Median age at first event (years) | 72.76 | 72.29 | 73.44 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 633
- Matched controls
- 6330
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G53.0
ICD-10 Finland
Postzoster neuralgia
467.5
307.7
284
11
B02.9
ICD-10 Finland
Zoster without complication
21.9
307.7
305
258
G53.0*B02.20
ICD-10 Finland
Trigeminal neuralgia after shingles
849.1
242.2
223
*
J05AB11
ATC
valaciclovir; oral
11.6
217.8
332
548
N03AX12
ATC
[U] gabapentin; oral
11.3
208.3
316
515
B02.8
ICD-10 Finland
Zoster with other complications
74.0
183.8
100
16
N03AX16
ATC
[U] pregabalin
9.3
180.0
362
797
J05AB01
ATC
aciclovir; systemic
8.8
170.6
377
908
G53.0*B02.21
ICD-10 Finland
Postherpetic geniculate ganglionitis
976.9
159.9
150
*
S70
ICPC
Herpes zoster
14.0
112.2
111
95
G530, B028,
ICD-10 Finland
1225.8
108.8
103
*
N02BF01
ATC
gabapentin; oral
7.4
100.8
175
309
B02
ICD-10 Finland
Zoster [herpes zoster]
9.7
97.3
126
158
N06AX21
ATC
duloxetine; oral
7.0
94.5
174
325
N02BF02
ATC
pregabalin; oral
7.7
80.7
127
199
N02AX02
ATC
tramadol; systemic, rectal
4.5
73.4
422
1939
G56.0
ICD-10 Finland
Carpal tunnel syndrome
10.3
62.2
73
79
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
28.4
58.6
40
15
B02.20
ICD-10 Finland
Herpes zoster trigeminal neuralgia
141.4
49.6
52
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
48.7
198
680
H02AB06
ATC
prednisolone; systemic
3.2
42.5
406
2284
N06AX16
ATC
venlafaxine; oral
3.9
39.6
136
411
G50.0
ICD-10 Finland
Trigeminal neuralgia
54.9
39.1
46
9
N03AF01
ATC
carbamazepine; oral, rectal
5.7
38.8
77
149
N02AA05
ATC
oxycodone; systemic
3.0
35.9
216
922
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
9.5
34.6
42
47
N02AJ06
ATC
codeine and paracetamol; systemic
2.8
34.5
327
1766
N03AX09
ATC
lamotrigine; oral
6.8
34.3
56
89
G51.0
ICD-10 Finland
Bell palsy
179.3
33.0
34
*
A01
ICPC
Pain general/multiple sites
3.6
32.3
124
401
B02.21
ICD-10 Finland
Herpes zoster neuralgia in another cranial nerve
76.0
32.2
36
5
ACC51
NOMESCO Finland
Release of median nerve
339.9
32.2
32
*
N03AF02
ATC
oxcarbazepine; oral
7.6
31.3
46
65
N06AA09
ATC
amitriptyline; systemic
3.7
30.8
109
333
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
29.8
403
2528
R51.80
ICD-10 Finland
Headache
3.2
29.1
138
507
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
28.7
330
1906
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
28.1
281
1517
G530, B029,
ICD-10 Finland
+∞
27.3
26
*
B02.3
ICD-10 Finland
Zoster ocular disease
38.6
26.4
33
9
A02BC02
ATC
pantoprazole; systemic
2.8
25.9
497
3577
R53
ICD-10 Finland
Malaise and fatigue
2.4
22.8
230
1223
S01AD03
ATC
aciclovir; ophthalmic
5.0
22.6
51
110
J01DB01
ATC
cefalexin; oral
3.2
22.4
551
4304
M79.6
ICD-10 Finland
Pain in limb
2.3
22.2
320
1972
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
22.2
177
845
M54.5
ICD-10 Finland
Low back pain
2.3
22.1
261
1480
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
21.6
281
1655
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
51.9
21.3
25
5
L04AX01
ATC
azathioprine; systemic
4.8
20.9
49
109
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.9
20.9
65
180
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
20.8
117
467
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
20.5
123
508
R06.0
ICD-10 Finland
Dyspnoea
2.3
20.4
236
1318
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.9
20.3
109
424
R51.81
ICD-10 Finland
Facial pain NOS
7.1
19.7
30
44
G63.0*B02.29
ICD-10 Finland
Postherpetic polyneuropathy
108.5
19.7
21
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
19.6
120
500
A02BC05
ATC
esomeprazole; systemic
2.2
19.5
293
1808
L28
ICPC
Limited function/disability (L)
2.3
19.3
185
951
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
19.3
232
1311
S01
ICPC
Pain/tenderness of skin
4.0
19.2
58
157
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
19.2
158
759
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.0
19.0
34
59
R52.2
ICD-10 Finland
Other chronic pain
4.8
18.7
43
94
R03AC02
ATC
salbutamol; inhalant
2.1
18.6
371
2534
R11
ICD-10 Finland
Nausea and vomiting
3.0
18.4
92
343
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
18.4
144
675
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.8
18.1
57
159
N02BE01
ATC
paracetamol; systemic, rectal
4.2
18.0
597
5053
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
17.9
107
439
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.1
17.8
283
1767
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
17.6
163
821
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.4
17.5
46
112
G50.1
ICD-10 Finland
Atypical facial pain
21.6
17.4
25
12
H04.10
ICD-10 Finland
Dry eye syndrome
2.8
17.4
100
402
R50.9
ICD-10 Finland
Fever, unspecified
2.5
17.4
130
595
AA1AD
NOMESCO Finland
CT of head and brain
2.1
17.2
254
1539
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
17.2
148
722
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.5
17.0
61
186
XW000
NOMESCO Finland
Bone marrow biopsy
4.0
17.0
50
133
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
16.9
235
1391
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.1
16.1
70
241
C03CA01
ATC
furosemide; systemic
2.0
15.5
289
1887
S18
ICPC
Laceration/cut
2.0
15.4
332
2274
H01
ICPC
Ear pain/earache
2.8
15.4
87
346
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.3
15.2
60
194
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
15.2
155
808
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
15.2
244
1509
H03.1*B02.3
ICD-10 Finland
Zoster blepharitis
24.1
15.2
21
9
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
15.2
330
2264
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.6
15.2
37
85
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
14.8
153
802
L04AA06
ATC
mycophenolic acid; systemic
6.8
14.6
23
35
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
14.5
186
1057
N01
ICPC
Headache
2.7
14.5
83
332
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
14.5
100
439
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
14.2
72
270
N06AA10
ATC
nortriptyline; systemic
6.6
14.2
23
36
A02BC01
ATC
omeprazole; systemic
2.0
14.1
206
1225
G530, B022,
ICD-10 Finland
+∞
13.6
13
*
R05
ICPC
Cough
2.0
13.5
181
1043
R52.0
ICD-10 Finland
Acute pain
4.4
13.3
34
81
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
13.3
142
751
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
13.2
83
348
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.2
13.1
53
174
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.3
13.0
114
555
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
29.0
13.0
17
6
R05
ICD-10 Finland
Cough
2.1
13.0
155
854
M25.5
ICD-10 Finland
Pain in joint
1.9
13.0
208
1272
R02
ICPC
Shortness of breath/dyspnoea
2.2
13.0
119
591
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
12.8
219
1369
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.2
12.7
51
167
M03BX02
ATC
tizanidine; oral
1.8
12.7
359
2626
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.7
12.6
75
305
ZX120
NOMESCO Finland
Intravenous
2.5
12.6
83
355
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
12.5
319
2255
H62.1*B02.8
ICD-10 Finland
Otitis externa in zoster
132.5
12.5
13
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
12.5
91
409
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
12.1
176
1037
H02AB04
ATC
methylprednisolone; systemic
2.2
12.1
112
558
J01FA10
ATC
azithromycin; systemic
1.8
12.0
331
2387
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.2
12.0
32
79
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
12.0
249
1648
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.0
12.0
34
88
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
12.0
53
184
N03AE01
ATC
clonazepam; systemic
3.3
11.9
46
147
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.8
11.8
36
98
L03
ICPC
Low back symptom/complaint
1.9
11.8
187
1133
SPAT1263
SPAT
Sampling
1.8
11.7
277
1902
TAC00
NOMESCO Finland
Peripheral nerve block
30.7
11.7
15
5
G56.2
ICD-10 Finland
Lesion of ulnar nerve
19.4
11.6
17
9
Z71.8
ICD-10 Finland
Other specified counselling
1.9
11.6
224
1445
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
11.6
86
389
R03BA05
ATC
fluticasone; inhalant
2.1
11.6
123
646
R52.9
ICD-10 Finland
Pain, unspecified
2.4
11.5
83
371
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.6
11.4
68
277
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
11.4
67
271
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
11.4
129
694
G44.2
ICD-10 Finland
Tension-type headache
2.3
11.3
94
446
M70.6
ICD-10 Finland
Trochanteric bursitis
2.2
11.3
105
523
R06AE07
ATC
cetirizine; oral
1.8
11.3
265
1812
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
11.2
73
311
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
3.4
11.1
40
122
R42
ICD-10 Finland
Dizziness and giddiness
1.9
11.1
186
1145
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
11.1
148
844
A07AA02
ATC
nystatin; oral
2.9
11.1
54
198
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
11.0
270
1868
M01AH05
ATC
etoricoxib; oral
1.8
10.9
363
2736
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
12.2
10.9
19
16
A99
ICPC
Disease/condition unspecnature/site
2.3
10.9
88
413
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.7
10.9
59
229
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
10.8
123
661
A04
ICPC
Weakness/tiredness general
2.0
10.8
130
713
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
10.8
156
913
M48.0
ICD-10 Finland
Spinal stenosis
2.2
10.8
98
483
L17
ICPC
Foot/toe symptom/complaint
1.8
10.7
209
1348
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
10.7
153
893
N05CF01
ATC
zopiclone; oral
1.8
10.6
235
1572
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.4
10.6
78
351
K08.80
ICD-10 Finland
Toothache NOS
2.8
10.6
55
209
UJF32
NOMESCO Finland
Coloscopy
1.8
10.5
190
1194
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
10.5
49
175
R07.3
ICD-10 Finland
Other chest pain
2.4
10.5
81
372
S29
ICPC
Skin symptom/complaint other
2.0
10.5
143
821
B02.2
ICD-10 Finland
Zoster with other nervous system involvement
111.8
10.4
11
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
10.4
85
401
A46
ICD-10 Finland
Erysipelas
2.0
10.4
120
649
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.9
10.3
163
981
L04AX03
ATC
methotrexate; systemic
2.5
10.3
70
304
TQW99
NOMESCO Finland
Other minor procedure on skin
2.8
10.0
53
203
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
10.0
112
599
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
9.9
68
296
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.4
9.9
25
59
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
9.9
162
985
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.3
9.9
38
121
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
9.9
37
116
D07AC01
ATC
betamethasone; topical
1.7
9.9
238
1625
SPAT1254
SPAT
Administration of medicine
2.0
9.8
117
639
N06AX11
ATC
mirtazapine; oral
1.8
9.8
227
1531
H57.1
ICD-10 Finland
Ocular pain
3.5
9.7
33
97
M01AB05
ATC
diclofenac; systemic, rectal
1.7
9.7
394
3095
J01MA12
ATC
levofloxacin; systemic
1.9
9.6
140
818
L04AA01
ATC
[U] ciclosporin
8.6
9.6
20
24
TAB00
NOMESCO Finland
Lumbar puncture
3.3
9.6
36
113
J01MA02
ATC
ciprofloxacin; systemic
1.7
9.5
269
1913
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
9.5
214
1429
J02AC01
ATC
fluconazole; systemic
1.7
9.5
224
1516
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.8
9.5
47
174
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
9.4
414
3312
J01AA02
ATC
doxycycline; systemic
1.9
9.4
494
4158
N30.0
ICD-10 Finland
Acute cystitis
1.9
9.3
134
780
S22.3
ICD-10 Finland
Fracture of rib
2.5
9.3
60
254
Z02.7
ICD-10 Finland
Issue of medical certificate
2.6
9.3
57
236
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.4
9.2
64
280
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
9.2
95
492
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.8
9.1
171
1082
SFA10
NOMESCO Finland
One-surface restoration
1.7
9.1
308
2291
M04AA01
ATC
allopurinol; systemic
2.0
9.1
109
596
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
9.0
52
208
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
9.0
198
1309
WW200
NOMESCO Finland
Immunization
4.3
9.0
23
55
J45.1
ICD-10 Finland
Nonallergic asthma
2.5
8.9
57
240
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
8.8
51
205
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
8.7
61
268
L03AA02
ATC
filgrastim; parenteral
3.5
8.7
30
89
ZYC01
NOMESCO Finland
Remote contact by phone
2.7
8.7
46
176
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
8.7
65
295
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
8.6
73
349
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
8.6
201
1350
S19
ICPC
Skin injury other
3.0
8.6
38
132
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
8.6
58
251
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
8.6
71
336
R60.0
ICD-10 Finland
Localized oedema
2.0
8.5
102
556
J01FA06
ATC
roxithromycin; oral
1.7
8.5
251
1791
J01CA04
ATC
amoxicillin; systemic
1.8
8.5
486
4113
R01AD12
ATC
fluticasone furoate; nasal
1.8
8.5
164
1042
UDC00
NOMESCO Finland
Ear microscopy
2.4
8.5
58
252
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.5
8.5
53
221
JN4AD
NOMESCO Finland
Body CT examination
2.1
8.5
90
470
A06AD11
ATC
lactulose; oral
1.9
8.4
126
742
P01BA02
ATC
hydroxychloroquine; oral
2.4
8.4
61
273
SPAT1216
SPAT
Assessment of functional ability
1.9
8.3
130
775
L50.0
ICD-10 Finland
Allergic urticaria
4.2
8.3
22
54
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.9
8.3
24
63
127
Kela drug reimbursment
Transplant complication
7.2
8.3
19
27
M54.1
ICD-10 Finland
Radiculopathy
3.4
8.3
29
87
L15
ICPC
Knee symptom/complaint
1.8
8.3
167
1074
N29
ICPC
Neurological sympt/complt other
4.3
8.3
21
50
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.1
8.2
35
119
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.7
8.2
26
73
H02AB09
ATC
hydrocortisone; systemic
4.5
8.2
20
46
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
8.2
64
296
L05
ICPC
Flank/axilla symptom/complaint
2.5
8.1
54
232
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
8.1
190
1275
WW500
NOMESCO Finland
Blood transfusion
2.9
8.0
38
137
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
8.0
189
1268
M79.1
ICD-10 Finland
Myalgia
2.0
8.0
95
516
J01FF01
ATC
clindamycin; systemic
1.7
8.0
169
1100
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.1
8.0
33
110
R07.0
ICD-10 Finland
Pain in throat
2.8
8.0
40
149
C08CA01
ATC
amlodipine; oral
1.6
8.0
284
2117
J01MA14
ATC
moxifloxacin; systemic
2.2
8.0
69
333
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.7
7.9
18
39
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.7
7.9
18
39
L08
ICPC
Shoulder symptom/complaint
1.8
7.9
143
890
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
7.9
194
1315
A03
ICPC
Fever
2.0
7.9
93
504
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
7.9
149
940
J01FA09
ATC
clarithromycin; systemic
1.7
7.8
181
1208
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.3
7.8
20
48
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.3
7.8
29
91
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
7.7
140
871
L11
ICPC
Wrist symptom/complaint
2.3
7.7
58
263
B02.29
ICD-10 Finland
Herpes zoster polyneuropathy
45.5
7.7
9
*
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.8
7.7
39
146
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
7.7
359
2846
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.1
7.7
31
102
M01AE02
ATC
naproxen; oral, rectal
1.6
7.7
327
2538
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
18.6
7.6
11
6
SPAT1153
SPAT
Removal of sutures
1.7
7.6
204
1413
R03AK08
ATC
formoterol and beclometasone; inhalant
2.9
7.6
36
130
E0000UV, ,
ATC
1.6
7.6
260
1913
XQ800
NOMESCO Finland
Prick test
2.7
7.6
41
159
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.1
7.6
76
388
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
7.5
45
184
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.4
7.5
54
241
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
7.5
122
736
Z01.2
ICD-10 Finland
Dental examination
1.6
7.4
252
1850
Z3231
NOMESCO Finland
Registered nurse
1.7
7.3
180
1217
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.6
7.3
42
168
R03BA01
ATC
beclometasone; inhalant
2.0
7.3
88
480
D01
ICPC
Abdominal pain/cramps general
2.0
7.3
79
415
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
7.3
53
237
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
7.3
7
*
G530, B0229,
ICD-10 Finland
+∞
7.3
7
*
N01BX04
ATC
capsaicin; inhalant, oral, topical, transdermal
+∞
7.3
7
*
SPAT1229
SPAT
Assessment of need for aid
2.2
7.3
65
317
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
7.3
250
1836
A02BC03
ATC
lansoprazole; oral
1.6
7.3
192
1322
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
4.4
7.3
18
42
R01AD09
ATC
mometasone; nasal
1.6
7.2
249
1829
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.6
7.2
41
163
C09CA06
ATC
candesartan; oral
1.7
7.2
155
1010
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.6
7.2
17
38
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
7.2
251
1851
B01.9
ICD-10 Finland
Varicella without complication
30.4
7.2
9
*
S20.2
ICD-10 Finland
Contusion of thorax
2.6
7.2
40
158
R04.0
ICD-10 Finland
Epistaxis
2.2
7.1
63
306
K81.0
ICD-10 Finland
Acute cholecystitis
3.8
7.1
21
56
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.1
7.1
19
47
XA402
NOMESCO Finland
ENMG
5.7
7.1
19
34
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.5
7.1
45
189
R03DC03
ATC
montelukast; oral
1.9
7.1
99
568
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
7.1
128
795
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
7.1
74
384
K02.1
ICD-10 Finland
Caries of dentine
1.6
7.1
312
2424
B34.9
ICD-10 Finland
Viral infection, unspecified
4.3
7.1
18
43
W19
ICD-10 Finland
Unspecified fall
2.0
7.0
75
392
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.0
393
3222
R01AD08
ATC
fluticasone; nasal
1.7
7.0
157
1035
L04AD01
ATC
ciclosporin; systemic
5.9
7.0
18
31
M43.1
ICD-10 Finland
Spondylolisthesis
3.0
6.9
30
103
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.3
6.9
26
82
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.4
6.9
24
72
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
6.9
524
4624
Z2446
NOMESCO Finland
Social worker
2.4
6.8
49
218
SPAT1301
SPAT
No procedures
1.6
6.8
207
1471
M05BA04
ATC
alendronic acid; oral
2.0
6.8
82
447
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
11.1
6.8
12
11
N03
ICPC
Pain face
11.1
6.8
12
11
M54.3
ICD-10 Finland
Sciatica
2.6
6.8
39
156
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.2
6.8
26
83
R21
ICPC
Throat symptom/complaint
1.8
6.8
103
607
R03BB04
ATC
tiotropium bromide; inhalant
2.0
6.8
77
412
T78.4
ICD-10 Finland
Allergy, unspecified
3.3
6.8
25
78
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
16.9
6.8
10
6
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
6.8
76
405
C07AB07
ATC
bisoprolol; oral
1.5
6.7
348
2790
D07AD01
ATC
clobetasol; topical
1.8
6.7
108
647
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
6.7
82
450
XG410
NOMESCO Finland
Flow-volume spirometry
2.8
6.7
34
128
R03AK07
ATC
formoterol and budesonide; inhalant
1.8
6.7
119
736
ZXA10
NOMESCO Finland
Bilateral
1.7
6.6
140
907
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
6.6
295
2286
KMAK, ,
NOMESCO Finland
1.6
6.6
267
2024
A11
ICPC
Chest pain NOS
2.0
6.6
71
372
R4120
NOMESCO Finland
Occupational therapy
2.4
6.6
45
196
SPAT1255
SPAT
Intravenous administration of medicine
2.3
6.6
51
235
A98
ICPC
Health maint/preventive medicine
2.2
6.6
585
5367
-1, ,
NOMESCO Finland
1.6
6.5
176
1214
L13
ICPC
Hip symptom/complaint
1.7
6.5
134
862
A10AB05
ATC
insulin aspart; parenteral
2.2
6.5
52
243
SPAT1325
SPAT
Vaccination
1.6
6.5
230
1692
M10.9
ICD-10 Finland
Gout, unspecified
2.2
6.5
56
270
K30
ICD-10 Finland
Functional dyspepsia
2.0
6.5
71
375
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
6.5
105
631
WX109
NOMESCO Finland
Extensive surface anesthesy of skin with external ointment or geel
70.5
6.4
7
*
R01AD58
ATC
fluticasone, combinations; nasal
1.7
6.4
117
727
R4110
NOMESCO Finland
Physiotherapy
1.6
6.4
181
1262
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
6.4
67
348
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
6.4
228
1679
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.2
6.4
25
81
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
6.4
122
769
R20.2
ICD-10 Finland
Paraesthesia of skin
2.5
6.4
41
174
R06AE09
ATC
levocetirizine; oral
1.9
6.3
79
436
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
6.3
148
984
C01DA14
ATC
isosorbide mononitrate; oral
1.7
6.3
134
870
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
+∞
6.3
6
*
A29
ICPC
General symptom/complaint other
1.8
6.3
105
637
L12
ICPC
Hand/finger symptom/complaint
1.8
6.2
101
606
D09
ICPC
Nausea
2.7
6.2
33
127
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
6.2
155
1047
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
6.2
83
469
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
6.2
244
1833
F01
ICPC
Eye pain
3.5
6.2
21
62
G04CA02
ATC
tamsulosin; oral
1.6
6.2
160
1091
L88
ICPC
Rheumatoid/seropositive arthritis
2.8
6.2
31
116
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
6.2
117
735
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.2
233
1735
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.5
6.2
38
158
M01AC01
ATC
piroxicam; systemic, rectal
1.9
6.1
87
501
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
6.1
159
1085
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.4
6.1
43
190
XF404
NOMESCO Finland
Ambulatory ECG
2.0
6.1
67
354
R4110, ,
SPAT
1.8
6.1
90
525
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.7
6.1
19
53
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
6.1
41
178
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.6
6.1
33
129
R51
ICD-10 Finland
Headache
2.6
6.0
35
141
H15.1
ICD-10 Finland
Episcleritis
6.1
6.0
15
25
D11
ICPC
Diarrhoea
1.9
6.0
72
392
N05BB01
ATC
hydroxyzine; systemic
2.3
6.0
44
198
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
29
13.49
38.61
1.3
1.1
—
—
—
0
0
127
401
3.71
34.37
3.8
2.9
9.48
10.99
g/l
2.06
119
361
420
2668
2.71
30.61
7.6
4.8
34.65
34.87
g/l
0.33
397
2492
29
26
11.64
27.74
2.5
2.3
—
—
—
0
0
52
101
5.52
25.94
3.8
5.5
147.43
242.50
iu/ml
—
7
14
446
3045
2.57
25.91
10.6
6.6
1.21
1.21
mmol/l
0.14
387
2623
549
4169
3.39
25.83
12.9
8.1
77.15
80.86
u/l
1.29
538
3928
448
3085
2.55
25.21
14.4
9.5
4.53
4.23
e9/l
1.55
406
2653
414
2752
2.46
25.16
8.4
6.0
1.20
1.21
mmol/l
1.06
386
2515
437
2989
2.49
24.73
8.5
6.6
11.03
12.27
umol/l
1.91
430
2848
306
1805
2.35
24.16
2.9
2.2
268.60
246.29
u/l
0.11
288
1704
157
686
2.71
23.73
7.0
4.0
260.37
245.89
u/l
0.53
151
646
378
2452
2.34
23.72
4.0
2.9
253.30
128.42
ug/l
1.21
351
2250
469
3349
2.55
23.57
7.4
4.9
6.75
6.73
mmol/l
0.05
458
3187
195
957
2.50
23.13
3.3
2.3
2.33
2.29
g/l
0.56
186
893
185
890
2.52
22.87
3.3
2.3
23.68
21.39
%
0.46
179
836
32
44
7.61
22.23
1.3
1.2
—
—
—
0
0
522
3971
2.79
22.16
7.3
4.3
15.16
13.98
mm/h
0.87
506
3653
219
1154
2.37
22.01
2.8
1.9
—
—
—
0
0
59
156
4.07
20.21
1.7
1.6
0.22
0.23
g/l
0.18
53
151
372
2503
2.18
19.95
3.1
2.4
80.59
79.43
nmol/l
0.33
342
2211
123
515
2.72
19.93
3.5
2.5
65.32
66.19
g/l
0.57
112
471
407
2843
2.21
19.77
22.5
18.1
1.29
1.34
inr
0.98
358
2386
282
1743
2.11
18.42
3.4
2.4
54.54
64.54
u/l
1.58
263
1606
320
2083
2.08
18.10
4.7
3.2
1879.42
1510.68
ng/l
0.76
291
1819
214
1199
2.19
17.92
2.1
1.6
1.12
1.45
mg/l
1.49
178
950
264
1609
2.10
17.73
2.9
2.3
3.01
3.01
mg/l
0.01
229
1376
107
458
2.61
16.41
1.8
1.6
—
—
—
0
0
40
94
4.47
15.94
2.1
1.3
80.00
—
titre
—
5
0
40
94
4.47
15.94
2.1
1.3
286.67
180.00
titre
—
6
8
505
4003
2.29
15.84
4.9
4.3
15.26
15.04
pmol/l
1.16
473
3611
35
74
4.95
15.83
2.4
2.9
1143.33
654.63
u/ml
—
6
8
320
2161
1.97
15.54
5.5
3.5
—
—
—
0
0
111
498
2.49
15.39
2.8
1.9
350.03
404.81
nmol/l
1.77
106
461
177
970
2.14
15.32
1.9
1.4
2.13
2.67
g/l
2.94
117
544
333
2289
1.96
15.26
6.4
4.1
40.37
80.30
ng/l
0.83
265
1756
429
3223
2.03
15.10
4.1
3.2
58.52
51.99
u/l
0.66
402
2971
375
2697
1.96
14.89
2.6
2.2
93.05
95.32
pmol/l
0.41
216
1393
228
1388
2.00
14.76
4.2
2.7
4.55
5.55
e6/l
1.09
210
1266
227
1387
1.99
14.49
4.6
2.8
341.76
354.34
umol/l
1.00
202
1197
52
159
3.47
14.41
2.0
1.6
—
—
—
0
0
175
977
2.09
14.30
4.9
3.1
0.80
0.82
mmol/l
1.91
164
912
152
804
2.17
14.29
8.9
4.7
1.06
1.03
mmol/l
0.52
142
734
156
841
2.13
13.93
2.7
1.9
—
—
—
0
0
160
884
2.08
13.33
2.6
1.8
—
—
—
0
0
391
2912
1.90
13.30
5.8
4.3
0.00
0.00
estimate
-0.00
90
634
394
2949
1.89
13.11
5.9
4.3
17.19
5.33
estimate
0.30
90
657
308
2140
1.86
12.92
3.9
3.5
2.36
2.36
mmol/l
0.21
285
1922
81
342
2.57
12.66
1.6
1.4
—
—
—
0
0
394
2968
1.87
12.64
6.0
4.3
0.00
0.49
estimate
0.52
83
623
145
793
2.07
12.32
1.3
1.3
5.98
15.49
u/ml
1.88
52
281
315
2228
1.82
12.26
6.4
4.2
64.70
143.04
e6/l
1.31
245
1608
288
1985
1.83
12.18
5.7
3.5
30.30
66.74
e6/l
2.01
243
1542
59
216
2.91
12.13
1.8
2.2
42.54
39.41
u/l
0.45
50
189
57
205
2.96
12.09
4.7
3.5
47.03
68.20
mg/l
0.44
50
176
57
205
2.96
12.09
4.7
3.5
118.49
84.63
mg/l
0.21
49
173
360
2664
1.81
11.95
3.2
2.7
—
—
—
0
0
153
863
2.02
11.91
1.4
1.3
59.85
37.67
iu/ml
0.47
44
271
196
1205
1.91
11.86
7.0
4.3
669.27
320.94
ng/l
0.59
173
1022
582
5094
2.77
11.70
37.2
17.8
24.18
26.34
mg/l
0.86
543
4274
254
1703
1.82
11.62
5.4
3.4
0.42
0.51
e6/l
0.26
204
1273
272
1873
1.79
11.31
2.0
1.8
20.26
20.35
nmol/l
0.03
239
1572
52
188
2.92
10.93
4.6
3.2
15.82
2.91
ratio
0.60
36
102
161
952
1.93
10.82
2.4
1.9
29.90
29.53
s
0.34
155
921
47
164
3.02
10.51
2.0
1.6
—
—
—
0
0
337
2504
1.74
10.49
3.7
2.7
—
—
estimate
—
0
0
44
149
3.10
10.36
1.6
1.5
1.86
0.11
iu/ml
—
6
29
41
134
3.20
10.24
1.7
1.5
—
—
—
0
0
247
1694
1.75
10.13
4.4
3.2
32.39
33.89
u/l
0.16
238
1599
550
4788
2.13
9.61
6.7
5.4
1.93
2.02
mu/l
0.90
523
4339
67
295
2.42
9.55
1.7
1.7
1.40
1.60
g/l
0.84
58
265
36
115
3.26
9.33
1.2
1.3
17.21
11.40
e6/l
0.26
28
80
37
121
3.19
9.24
1.7
1.5
—
—
—
0
0
36
116
3.23
9.21
1.3
1.3
64.07
1209.60
e6/l
0.57
28
85
112
616
1.99
9.18
3.7
2.9
6.77
8.73
umol/l
1.05
99
544
36
117
3.20
9.08
1.7
1.5
—
—
—
0
0
72
335
2.30
9.06
6.6
3.6
2.60
2.00
mmol/l
0.52
54
260
169
1067
1.80
9.04
4.5
3.1
1.50
1.25
e6/l
0.34
108
574
18
21
8.79
8.84
1.2
1.1
—
—
—
0
0
62
273
2.41
8.83
1.6
1.3
566.00
170.63
u/ml
0.70
55
250
118
672
1.93
8.72
4.5
3.2
2.69
1.89
mmol/l
1.66
109
568
589
5316
2.55
8.71
40.3
21.9
4.01
3.99
mmol/l
0.91
584
5190
88
454
2.09
8.57
2.3
1.7
—
—
—
0
0
588
5311
2.51
8.53
39.9
21.8
139.27
139.61
mmol/l
2.19
583
5197
102
557
1.99
8.50
2.9
2.5
30.08
32.46
u/l
0.42
90
459
129
763
1.87
8.47
6.6
6.8
2.42
1.08
mmol/l
3.52
112
630
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
18
23
8.02
8.41
1.3
1.2
—
—
—
0
0
19
41
4.75
8.40
1.1
1.0
—
—
—
0
0
53
224
2.49
8.25
2.7
2.9
—
—
—
0
0
200
1362
1.68
8.04
3.7
2.3
—
—
—
0
0
291
2181
1.62
8.00
5.7
4.3
0.34
0.04
estimate
0.45
77
516
98
539
1.97
7.98
3.4
2.5
5.27
6.51
ug/l
0.30
89
465
19
43
4.52
7.94
1.2
1.1
—
—
—
0
0
56
248
2.38
7.88
3.8
2.0
4.16
4.13
g/l
0.08
49
222
56
248
2.38
7.88
3.8
2.0
3.43
3.81
g/l
1.05
49
222
56
248
2.38
7.88
3.8
2.0
7.55
7.47
g/l
0.11
48
222
53
230
2.42
7.80
3.9
2.1
2.84
3.09
g/l
0.93
46
204
51
218
2.46
7.75
3.9
2.4
1.76
1.14
g/l
0.42
40
187
548
4856
1.96
7.73
7.9
6.8
40.86
39.72
mmol/mol
1.94
507
4500
48
200
2.51
7.70
2.0
1.7
9.16
6.43
iu/ml
—
9
48
587
5338
2.37
7.67
20.6
12.4
23.86
24.20
u/l
0.23
580
5160
42
165
2.66
7.59
1.2
1.3
—
—
—
0
0
18
28
6.58
7.45
3.7
3.5
—
—
—
0
0
53
237
2.35
7.31
3.2
1.9
—
—
—
0
0
30
100
3.10
7.29
1.8
1.5
—
—
—
0
0
591
5409
2.40
7.27
44.3
24.0
87.15
80.33
umol/l
2.93
586
5331
22
60
3.76
7.24
1.6
1.8
—
—
—
0
0
36
134
2.79
7.21
1.8
2.2
11.53
13.10
mg/l
0.50
31
123
37
140
2.74
7.19
1.1
1.3
7.80
5.57
u/ml
—
6
26
24
70
3.52
7.18
1.3
1.3
123.06
171.57
au/ml
—
5
20
50
220
2.38
7.15
3.3
2.0
9.99
10.65
g/l
0.45
42
193
87
478
1.95
7.09
4.4
3.4
98.07
87.29
ng/l
0.63
76
408
40
159
2.62
7.07
1.4
1.5
—
—
—
0
0
100
579
1.86
6.95
2.9
2.2
137.65
137.79
ug/g
0.00
83
453
165
1104
1.67
6.95
1.3
1.2
0.69
1.56
u/ml
2.35
37
280
185
1280
1.63
6.81
6.0
4.6
1.02
1.02
kg/l
0.79
129
858
97
562
1.86
6.73
2.1
2.2
0.20
0.20
g/l
0.11
90
517
48
214
2.34
6.67
2.9
1.7
—
—
—
0
0
77
416
1.97
6.58
10.3
6.2
25.46
24.37
mmol/l
1.62
77
399
184
1281
1.62
6.58
1.8
1.8
453.42
5736578.39
pmol/l
0.50
155
1046
24
75
3.29
6.48
2.0
1.6
—
—
—
0
0
171
1173
1.63
6.48
1.9
1.8
1133.81
1229.20
nmol/l
0.76
135
878
44
192
2.39
6.42
1.2
1.2
0.30
2.53
u/ml
—
6
11
150
998
1.66
6.40
4.9
3.3
1.61
2.66
e6/l
1.15
88
501
256
1940
1.54
6.27
4.4
3.3
6.89
7.07
mmol/l
0.28
215
1619
553
4992
1.85
6.27
6.3
5.5
6.06
6.00
mmol/l
0.44
512
4505
547
4923
1.82
6.24
32.8
17.9
71.50
74.33
ml/min/173m2
2.23
514
4590
19
52
3.74
6.24
1.8
1.5
—
—
—
0
0
78
433
1.91
6.16
5.3
3.0
54.59
59.84
ml/min/173m2
0.58
41
200
25
83
3.09
6.14
1.9
1.6
—
—
—
0
0
29
105
2.85
6.13
2.3
1.8
—
—
—
0
0
72
390
1.95
6.11
3.2
3.3
24.27
24.14
mmol/l
0.13
72
385
224
1662
1.54
5.98
6.4
4.4
0.00
0.00
estimate
0.50
80
576
33
130
2.62
5.96
1.2
1.3
—
—
—
0
0
103
631
1.76
5.92
7.3
7.5
115.21
119.68
g/l
1.60
103
617
9
6
15.18
5.91
1.2
1.2
84.67
78.17
%
—
9
6
17
34
5.11
5.91
1.1
1.1
—
—
—
0
0
22
70
3.22
5.79
2.3
1.5
—
—
—
0
0
590
5471
2.15
5.76
51.1
27.3
239.81
244.93
e9/l
0.98
581
5353
16
41
3.98
5.74
2.0
1.4
—
—
—
0
0
590
5473
2.15
5.72
50.9
27.2
4.29
4.39
e12/l
4.87
581
5334
46
216
2.22
5.69
1.4
1.3
—
—
—
0
0
37
158
2.43
5.68
1.9
1.5
—
—
—
0
0
91
547
1.78
5.58
3.8
3.2
302.20
245.81
ng/l
0.43
86
513
86
513
1.78
5.41
3.1
2.6
0.38
0.68
e6/l
0.72
81
491
14
25
5.70
5.40
1.3
1.1
—
—
—
0
0
37
162
2.36
5.39
1.8
1.4
—
—
—
0
0
184
1339
1.53
5.25
3.3
3.1
2.47
2.46
mmol/l
0.49
164
1210
251
1956
1.47
5.10
4.6
3.9
11.11
7.86
mg/mmol
0.46
163
1215
40
186
2.23
5.08
3.0
2.1
0.00
0.00
g/l
-0.00
30
165
39
180
2.24
5.05
4.0
3.5
0.96
0.83
nmol/l
0.77
32
151
541
4932
1.67
4.90
5.9
5.1
1.44
1.47
mmol/l
0.93
500
4493
13
25
5.29
4.79
1.2
1.5
—
—
—
0
0
522
4729
1.59
4.71
5.0
4.3
1.38
1.26
mmol/l
3.54
476
4248
27
109
2.54
4.69
1.1
1.1
—
4.19
—
0
12
543
4968
1.65
4.69
6.0
5.2
4.48
4.51
mmol/l
0.32
504
4552
10
14
7.24
4.66
1.1
1.2
—
—
—
0
0
13
26
5.08
4.65
1.2
1.0
—
—
—
0
0
17
53
3.27
4.64
2.4
2.6
—
—
—
0
0
552
5081
1.68
4.53
6.8
6.1
2.51
2.59
mmol/l
1.31
515
4640
26
105
2.54
4.52
1.3
1.3
—
—
—
0
0
33
149
2.28
4.51
3.6
2.3
118.96
125.80
g/l
0.85
26
113
17
54
3.21
4.51
1.2
1.3
—
—
—
0
0
12
23
5.30
4.47
2.3
3.6
796.75
986.96
u/ml
0.30
12
23
39
190
2.12
4.45
3.8
2.1
0.00
0.00
g/l
-0.00
32
172
21
77
2.79
4.39
9.2
2.0
32.57
31.88
pg
0.23
21
77
93
601
1.64
4.37
2.6
2.7
4.32
4.32
kpa
0.01
93
578
19
66
2.94
4.36
1.2
1.3
—
—
—
0
0
19
66
2.94
4.36
1.2
1.3
—
—
—
0
0
72
436
1.73
4.31
1.6
1.4
—
—
—
0
0
8
9
8.98
4.29
1.0
1.0
—
—
—
0
0
19
67
2.89
4.26
1.2
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
201
2.06
4.22
3.5
2.5
0.32
0.35
iu/ml
0.23
27
116
19
68
2.85
4.15
1.2
1.3
—
—
—
0
0
17
57
3.04
4.15
2.3
2.1
—
—
—
0
0
33
155
2.19
4.13
2.0
1.6
—
—
—
0
0
21
80
2.68
4.10
1.3
1.2
—
—
—
0
0
19
69
2.81
4.05
1.2
1.3
—
—
—
0
0
19
69
2.81
4.05
1.2
1.3
—
—
—
0
0
36
177
2.10
4.03
3.2
2.1
0.00
0.00
g/l
-0.00
30
165
30
137
2.25
4.02
1.4
1.3
3644.21
21845.00
e6/l
2.52
19
90
9
14
6.50
3.99
1.2
1.1
—
—
—
0
0
22
88
2.55
3.92
1.3
1.2
9.95
11.71
u/l
0.25
17
70
6
5
12.10
3.77
1.2
1.2
—
—
—
0
0
76
485
1.64
3.76
7.1
3.7
1.22
1.22
mmol/l
0.15
67
417
17
61
2.84
3.71
2.2
1.6
—
—
—
0
0
17
61
2.84
3.71
2.2
1.6
—
—
—
0
0
17
61
2.84
3.71
2.2
1.6
—
—
—
0
0
13
34
3.88
3.71
2.3
1.4
—
—
—
0
0
10
20
5.06
3.70
1.4
1.3
—
—
—
0
0
18
67
2.74
3.68
1.0
1.0
—
2.57
—
0
8
12
30
4.06
3.61
2.4
1.9
—
—
—
0
0
12
30
4.06
3.61
2.4
1.9
—
—
—
0
0
12
30
4.06
3.61
2.4
1.9
—
—
—
0
0
12
30
4.06
3.61
2.4
1.9
—
—
—
0
0
27
124
2.23
3.59
1.6
1.4
34.67
29.23
iu/l
0.26
21
108
10
21
4.82
3.56
1.4
1.0
2472.00
1678.00
miu/ml
—
10
21
13
37
3.57
3.42
2.3
1.4
—
—
—
0
0
24
108
2.27
3.36
5.6
2.6
8.16
9.01
pmol/l
0.21
24
108
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
14
5.77
3.35
1.3
3.4
258.13
133.00
%
—
8
14
27
129
2.14
3.28
1.1
1.4
—
—
—
0
0
19
79
2.45
3.16
1.3
1.1
416.33
300.93
u/ml
0.41
12
42
18
73
2.51
3.15
4.1
3.9
—
—
—
0
0
13
44
3.00
3.15
1.1
1.1
—
—
—
0
0
9
21
4.33
3.00
1.4
1.3
—
—
—
0
0
5
5
10.06
2.98
1.0
2.0
—
—
—
0
0
32
171
1.92
2.91
1.3
1.2
—
—
—
0
0
32
171
1.92
2.91
1.3
1.2
—
—
—
0
0
20
89
2.29
2.89
1.4
1.3
—
—
—
0
0
205
1672
1.33
2.83
5.8
5.9
2.45
3.24
ug/l
0.64
179
1489
13
47
2.80
2.83
1.4
1.1
—
—
—
0
0
37
210
1.81
2.81
8.0
4.0
24.55
25.07
mmol/l
0.41
32
193
30
159
1.93
2.80
4.4
3.5
1.08
1.82
index
0.44
12
78
10
28
3.61
2.79
1.2
1.3
—
—
—
0
0
14
54
2.63
2.72
2.6
2.1
—
—
—
0
0
169
1349
1.34
2.68
4.7
4.8
21.71
21.87
%
0.04
80
698
15
61
2.49
2.63
1.0
1.1
—
18.92
—
0
16
12
44
2.76
2.56
1.0
1.2
126.67
100.93
pmol/l
0.88
12
44
6
11
5.50
2.55
1.2
1.3
—
—
—
0
0
7
16
4.41
2.48
1.6
1.0
11.18
8.80
ug/l
—
7
16
56
370
1.56
2.45
3.3
3.5
47.76
46.50
%
0.15
56
362
11
39
2.85
2.35
1.6
1.1
—
—
—
0
0
48
310
1.59
2.32
3.6
3.9
1.02
1.02
ratio
0.57
42
283
63
433
1.51
2.32
2.0
1.6
1.44
1.57
%
0.84
55
372
9
28
3.25
2.31
1.1
1.3
—
—
—
0
0
8
23
3.51
2.27
2.5
2.7
0.61
0.61
mmol/l
—
8
23
85
623
1.42
2.26
6.0
3.6
—
—
—
0
0
7
18
3.92
2.25
3.7
2.7
116.29
113.11
%
—
7
18
23
121
1.93
2.23
11.7
6.4
106.13
105.11
mmol/l
0.63
23
107
23
121
1.93
2.23
11.7
6.4
10.96
11.25
mmol/l
0.17
23
107
27
151
1.82
2.19
2.3
2.0
—
—
—
0
0
23
124
1.89
2.09
2.4
2.0
—
—
—
0
0
10
37
2.73
2.07
1.0
1.1
—
—
—
0
0
10
37
2.73
2.07
1.0
1.1
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
10
5.03
2.07
1.0
2.0
92.60
102.20
%
—
5
10
5
10
5.03
2.07
1.0
1.0
—
—
—
0
0
27
154
1.79
2.07
1.1
1.2
—
—
—
0
0
13
56
2.35
2.06
2.4
2.1
2273.56
4886.37
u/l
—
8
19
25
141
1.80
1.99
1.5
1.4
—
—
—
0
0
25
141
1.80
1.99
1.5
1.4
—
—
—
0
0
7
21
3.36
1.97
1.1
1.3
—
—
—
0
0
5
11
4.57
1.94
1.8
1.5
—
—
—
0
0
29
174
1.70
1.89
1.0
1.5
0.32
0.30
mg/l
0.08
14
75
7
22
3.21
1.88
1.0
1.1
—
—
—
0
0
9
34
2.67
1.87
3.9
1.5
73.56
78.70
ng/l
—
9
34
18
93
1.96
1.86
1.1
1.1
—
—
—
0
0
241
2100
1.24
1.84
2.1
1.9
1.36
1.29
mmol/l
0.70
201
1734
22
123
1.82
1.82
1.1
1.1
—
—
—
0
0
12
53
2.29
1.81
1.3
1.9
851.35
1215.57
mg
0.21
12
53
51
355
1.47
1.81
2.6
2.3
12.28
12.88
nmol/l
0.15
38
310
8
29
2.78
1.79
1.0
1.5
—
—
—
0
0
8
29
2.78
1.79
1.4
2.2
—
—
—
0
0
8
29
2.78
1.79
1.0
1.5
—
—
—
0
0
13
60
2.19
1.79
1.0
1.1
—
—
—
0
0
8
30
2.69
1.73
3.5
3.5
1.50
1.10
%
—
8
30
7
24
2.94
1.72
1.4
1.2
132.73
167.97
pmol/l
—
7
24
5
13
3.87
1.72
1.4
1.1
—
—
—
0
0
5
13
3.87
1.72
1.2
1.1
—
—
—
0
0
178
1514
1.24
1.67
5.1
3.8
0.00
0.06
estimate
0.60
75
489
10
41
2.46
1.65
1.0
1.1
—
—
—
0
0
5
14
3.59
1.62
1.8
1.2
—
—
—
0
0
28
175
1.63
1.60
1.3
1.4
290.23
265.82
ug/g
0.28
17
96
8
32
2.52
1.60
2.0
1.4
83.75
79.34
umol/l
—
8
32
9
37
2.45
1.48
1.2
1.3
—
—
—
0
0
9
37
2.45
1.48
1.2
1.3
—
—
—
0
0
9
38
2.39
1.46
1.0
1.1
—
—
—
0
0
34
229
1.51
1.44
1.3
1.3
—
—
—
0
0
5
16
3.14
1.44
1.0
1.0
—
—
—
0
0
5
16
3.14
1.44
1.2
1.3
—
—
—
0
0
5
16
3.14
1.44
2.6
1.7
1.64
1.38
nmol/l
—
5
11
28
181
1.57
1.42
1.5
1.6
53.58
19.10
u/ml
—
6
29
82
649
1.30
1.39
1.9
1.4
—
—
—
0
0
40
288
1.42
1.25
3.0
1.9
—
—
—
0
0
6
25
2.41
1.24
1.3
1.2
—
—
—
0
0
6
25
2.41
1.24
1.3
1.2
—
—
—
0
0
8
36
2.24
1.24
1.0
1.1
—
—
—
0
0
118
991
1.23
1.24
3.5
3.4
0.81
0.83
ug/l
0.06
71
685
5
19
2.64
1.22
1.2
1.2
—
—
—
0
0
6
26
2.32
1.19
1.0
1.0
—
—
—
0
0
6
26
2.32
1.19
2.3
1.4
673.00
296.80
mu/l
—
6
20
82
665
1.27
1.17
13.5
7.7
—
—
—
0
0
8
39
2.06
1.15
1.1
1.6
—
—
—
0
0
5
22
2.28
1.03
4.0
2.1
—
—
—
0
0
5
22
2.28
1.03
4.0
2.1
—
—
—
0
0
5
22
2.28
1.03
4.0
2.1
—
—
—
0
0
36
266
1.37
1.00
3.1
1.8
—
—
—
0
0
83
689
1.24
0.99
5.0
5.1
31.14
32.96
%
0.87
59
430
14
84
1.68
0.98
1.6
1.4
29974.22
1194.71
e6/l
—
9
56
11
64
1.73
0.86
1.2
1.3
0.58
29.44
nmol/l
0.49
11
59
20
137
1.47
0.85
1.2
1.2
—
—
—
0
0
5
24
2.09
0.74
1.2
1.4
—
—
—
0
0
25
333
0.74
0.74
1.8
2.0
3.22
3.33
ratio
0.18
17
271
36
282
1.29
0.73
1.1
1.2
189.47
123.02
u/ml
0.29
12
109
18
127
1.43
0.68
1.8
1.6
2.09
55.86
iu/l
—
7
46
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
12
80
1.51
0.60
1.3
2.9
40.20
24.07
mg/l
—
5
33
11
72
1.54
0.59
1.1
1.0
—
—
—
0
0
17
123
1.39
0.58
2.6
1.6
—
—
—
0
0
6
36
1.67
0.57
1.0
1.1
—
104.00
—
0
5
5
88
0.56
0.56
1.0
1.2
1.37
1.58
g/l
—
5
88
15
107
1.41
0.55
2.9
1.8
36.73
43.10
nmol/l
0.55
15
100
6
40
1.50
0.51
3.5
1.8
—
—
—
0
0
74
653
1.15
0.51
1.5
1.4
—
—
—
0
0
8
56
1.43
0.42
1.3
1.2
8.19
8.08
mmol/l
—
8
45
0
17
0.00
0.40
0.0
1.2
—
10.00
—
0
17
12
88
1.37
0.40
2.9
1.8
157.67
224.83
pmol/l
2.37
12
83
5
35
1.43
0.39
3.4
2.4
—
—
—
0
0
75
683
1.11
0.34
2.6
4.4
4.32
30.69
ug/l
1.45
62
567
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
15
186
0.80
0.31
3.6
3.0
1.53
1.63
mmol/l
0.32
15
181
7
97
0.72
0.31
1.3
1.3
0.89
0.89
g/l
—
7
97
7
54
1.30
0.30
1.4
1.3
—
—
—
0
0
7
55
1.28
0.30
1.1
1.1
1.80
1.56
nmol/l
—
7
47
10
129
0.77
0.28
7.3
3.7
24.86
25.62
mg/l
—
5
90
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
18.43
—
0
7
8
100
0.80
0.13
1.5
1.4
—
—
—
0
0
13
133
0.98
0.00
1.5
1.4
—
—
—
0
0
24
239
1.00
0.00
1.1
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
0.13
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
31.63
—
0
9
0
6
0.00
-0.00
0.0
4.0
—
0.67
—
0
6
0
6
0.00
-0.00
0.0
6.2
—
5.45
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint G6_POSTZOST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_POSTZOST | 1.259 [1.07, 1.48] | 0.005 |
| Birth year | 0.995 [0.99, 1.0] | 0.291 |
During the follow-up period (1.1.1998 — 31.12.2019), 668 out of 1848 females with G6_POSTZOST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_POSTZOST | 1.483 [1.21, 1.82] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 466 out of 1086 males with G6_POSTZOST died.
Mortality risk
Mortality risk for people of age
years, who have G6_POSTZOST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.109% | 0.277% |
| 5 | 0.642% | 1.793% |
| 10 | 1.732% | 4.78% |
| 15 | 3.376% | 8.816% |
| 20 | 6.006% | 14.731% |
Relationships between endpoints
↥Index endpoint: G6_POSTZOST – Postzoster neuralgia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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