Other endophthalmitis

H7_OTHENDOPHTHALMITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

225

4. Check minimum number of events

None

225

5. Include endpoints

None

225

6. Filter based on genotype QC (FinnGen only)

204

Control definitions (FinnGen only)

Control exclude
H7_VITREOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1770 938 814
Only index persons 1405 776 629
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 66.80 71.11 61.85
Only index persons 65.42 70.24 59.47

-FinnGen-

Key figures

All Female Male
Number of individuals 204 117 87
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 64.11 64.89 63.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
209
Matched controls
2090
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H44.1
ICD-10 Finland
Other endophthalmitis
+∞
231.7
177
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
34.0
136.0
102
57
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
55.9
106.8
63
16
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
19.3
62.8
54
37
CKA10
NOMESCO Finland
Biopsy of vitreous body
+∞
62.7
57
*
H44.0
ICD-10 Finland
Purulent endophthalmitis
+∞
61.6
56
*
WX140
NOMESCO Finland
Parabulbar anesthesy
15.4
59.6
59
52
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.3
36.0
65
121
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.9
34.5
91
243
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.8
32.8
63
124
S01ED51
ATC
timolol, combinations; ophthalmic
7.4
32.1
55
96
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
9.0
30.0
41
55
S01ED01
ATC
timolol; ophthalmic
12.0
28.7
31
30
H43.1
ICD-10 Finland
Vitreous haemorrhage
+∞
27.7
26
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.4
26.4
38
54
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.8
25.4
81
245
H20.1
ICD-10 Finland
Chronic iridocyclitis
102.9
25.3
27
*
XCK10
NOMESCO Finland
Photography of fundus of eye
5.5
23.2
54
125
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.0
21.7
128
590
XCH00
NOMESCO Finland
Eye pressure measurement
6.6
17.7
31
54
H33.0
ICD-10 Finland
Retinal detachment with retinal break
16.0
17.4
28
20
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
28.5
17.3
23
9
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.4
17.0
125
633
H26.4
ICD-10 Finland
After-cataract
4.3
17.0
53
153
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.4
15.9
46
125
S01EE01
ATC
latanoprost; ophthalmic
5.3
15.3
34
74
36609
ICD-8 Finland
Other inflammation of uveal tract, Unspecified
+∞
14.8
14
*
TCK20
NOMESCO Finland
Needle biopsy of vitreous body
+∞
14.8
14
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
15.2
13.6
22
16
WX142
NOMESCO Finland
Sub-tenon anesthesy
43.1
13.4
16
*
H16.0
ICD-10 Finland
Corneal ulcer
5.9
13.1
25
47
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
28.7
12.2
16
6
114
Kela drug reimbursment
Glaucoma
3.8
11.7
41
127
S01EA05
ATC
brimonidine; ophthalmic
12.9
11.6
20
17
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
+∞
11.6
11
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
126.7
11.5
12
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
16.3
11.5
18
12
XCK00
NOMESCO Finland
Perimetry
4.6
11.5
29
70
CKC12
NOMESCO Finland
Photocoagulation of retina
10.1
11.3
22
24
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
21.5
11.3
16
8
H02AB06
ATC
prednisolone; systemic
2.7
11.2
128
766
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
29.8
10.9
14
5
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
10.8
101
545
XCD20
NOMESCO Finland
Photoangiography of eye
11.5
10.5
19
18
H3603, E103,
ICD-10 Finland
115.6
10.5
11
*
S01BC03
ATC
diclofenac; ophthalmic
14.1
10.4
17
13
S01EC01
ATC
acetazolamide; systemic
8.8
10.1
21
26
H26.2
ICD-10 Finland
Complicated cataract
42.2
10.1
12
*
WX002
NOMESCO Finland
Sedation and analgesia
2.9
10.0
59
250
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
10.0
121
732
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
21.3
9.9
14
7
A10AA02, ,
ATC
5.7
9.8
19
36
S01BA04
ATC
prednisolone; ophthalmic
9.8
9.8
19
21
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
12.2
9.8
17
15
ZXD05
NOMESCO Finland
Urgent procedure
2.5
9.3
80
409
H40.0
ICD-10 Finland
Glaucoma suspect
3.9
9.2
29
83
S01BA07
ATC
fluorometholone; ophthalmic
14.9
8.8
14
10
S01EE05
ATC
tafluprost; ophthalmic
7.0
8.7
21
33
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
93.7
8.5
9
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
93.7
8.5
9
*
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
+∞
8.4
8
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
8.4
8
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
10.7
8.2
15
15
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
3.6
8.2
29
90
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
6.4
7.9
20
34
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.8
7.8
46
193
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
7.8
32
109
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
9.4
7.7
15
17
ZXA00
NOMESCO Finland
Right side
2.4
7.7
76
408
ZX198
NOMESCO Finland
Other local administration
26.1
7.6
10
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.1
7.6
10
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
26.1
7.6
10
*
S01BA01
ATC
dexamethasone; ophthalmic
6.4
7.6
19
32
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
7.3
7
*
36608
ICD-8 Finland
Other inflammation of uveal tract, Alia definita
+∞
7.3
7
*
S01EA03
ATC
apraclonidine; ophthalmic
16.5
7.3
11
7
H30.2
ICD-10 Finland
Posterior cyclitis
31.2
7.2
9
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
31.2
7.2
9
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
10.6
7.1
13
13
H35.6
ICD-10 Finland
Retinal haemorrhage
14.4
7.0
11
8
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.7
6.9
14
17
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
17.4
6.8
10
6
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
6.8
53
254
127
Kela drug reimbursment
Transplant complication
23.4
6.7
9
*
H20.8
ICD-10 Finland
Other iridocyclitis
72.0
6.5
7
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
72.0
6.5
7
*
H21.0
ICD-10 Finland
Hyphaema
72.0
6.5
7
*
A10AA01, ,
ATC
6.6
6.3
15
24
H44.5
ICD-10 Finland
Degenerated conditions of globe
+∞
6.3
6
*
TCH10
NOMESCO Finland
Needle aspiration of aqueous from anterior chamber
+∞
6.3
6
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
+∞
6.3
6
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
27.6
6.3
8
*
ZXA05
NOMESCO Finland
Left side
2.2
6.1
64
347
H34.8
ICD-10 Finland
Other retinal vascular occlusions
6.4
6.1
15
25
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.0
54
274
A10AB01
ATC
insulin (human); parenteral
5.3
6.0
17
34

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
76
260
4.02
19.58
3.0
2.1
—
—
—
0
0
19
12
17.27
12.40
1.2
1.5
—
—
—
0
0
19
14
14.79
11.71
2.3
3.0
16.34
—
iu/ml
—
5
0
15
8
20.07
10.42
1.1
1.3
—
—
—
0
0
22
48
5.00
9.78
1.2
1.1
—
—
—
0
0
17
16
11.45
9.48
1.2
1.3
—
—
—
0
0
48
201
2.80
8.19
2.2
1.8
—
—
—
0
0
49
212
2.71
7.83
2.4
1.4
—
—
—
0
0
11
6
19.25
7.68
1.0
1.0
2109.09
1537.83
miu/ml
—
11
6
10
6
17.40
6.81
3.4
1.8
542.50
1203.83
u/ml
—
10
6
16
31
5.50
5.84
2.0
1.4
—
—
—
0
0
27
107
2.75
5.03
1.6
1.8
—
—
—
0
0
44
233
2.13
4.35
14.9
5.1
1.03
1.04
mmol/l
0.11
44
210
80
538
1.79
3.87
6.3
4.2
—
—
—
0
0
85
582
1.78
3.87
7.8
4.0
7.40
7.40
ph
0.06
65
399
46
261
1.98
3.76
2.1
1.8
—
—
—
0
0
9
16
5.82
3.70
2.2
1.9
38.46
40.19
%
—
9
16
40
220
2.01
3.55
1.4
1.4
680.00
415.27
titre
—
6
55
31
158
2.13
3.36
3.1
2.1
0.00
0.00
estimate
—
5
35
114
875
1.67
3.26
10.9
6.0
0.59
0.58
e9/l
0.19
105
749
24
112
2.29
3.21
1.8
1.5
—
—
—
0
0
114
878
1.66
3.20
11.0
6.0
0.04
0.04
e9/l
0.20
105
753
19
80
2.51
3.16
2.8
2.0
0.00
0.00
estimate
—
7
26
117
910
1.65
3.13
11.4
6.4
0.19
0.19
e9/l
0.18
110
792
101
759
1.64
3.09
17.0
13.0
0.00
0.00
e9/l
0.60
87
626
122
962
1.64
3.07
6.9
4.2
0.00
0.00
estimate
-0.00
28
207
5
5
10.20
2.99
3.2
1.6
25.20
28.40
%
—
5
5
114
891
1.61
2.92
11.0
6.1
1.74
1.90
e9/l
0.64
106
791
108
839
1.59
2.80
8.2
4.5
34.71
35.42
g/l
0.68
101
779
16
66
2.54
2.78
1.3
1.3
—
—
—
0
0
6
10
6.14
2.71
3.8
1.4
178.67
57.36
ng/l
—
6
10
121
972
1.58
2.67
6.9
4.2
0.00
0.00
estimate
-0.00
26
193
20
95
2.22
2.58
1.0
1.2
—
—
—
0
0
5
7
7.28
2.56
2.8
2.0
—
—
—
0
0
118
951
1.55
2.51
6.1
4.1
0.00
0.00
estimate
-0.00
26
204
8
21
3.92
2.49
2.4
2.0
820.12
1059.44
e6/l
—
8
16
26
140
1.98
2.45
6.0
3.0
10.41
10.16
g/l
0.07
26
126
25
133
2.00
2.44
3.1
2.9
206.88
226.22
ng/l
0.07
25
117
54
368
1.63
2.34
4.9
3.7
46.32
202.12
ng/l
1.27
41
303
81
609
1.54
2.31
5.7
3.5
—
—
—
0
0
5
9
5.66
2.22
1.0
1.0
—
—
—
0
0
79
597
1.52
2.18
5.6
4.0
16.31
8.57
mg/mmol
0.62
58
371
6
14
4.38
2.16
3.3
4.1
—
—
—
0
0
6
14
4.38
2.16
1.3
1.1
—
—
—
0
0
115
942
1.49
2.13
13.9
6.6
1.22
1.21
mmol/l
0.28
102
818
110
893
1.49
2.13
19.7
15.8
1.31
1.29
inr
0.13
99
750
7
20
3.58
2.07
1.4
1.6
—
—
—
0
0
21
112
1.97
2.05
4.1
1.8
2.04
1.27
g/l
0.35
21
99
22
120
1.93
2.02
8.5
3.6
—
—
—
0
0
75
571
1.49
1.96
9.8
5.7
—
—
—
0
0
9
33
2.80
1.95
1.1
1.7
—
—
—
0
0
5
11
4.63
1.95
5.8
1.5
2.84
1.56
mmol/l
—
5
11
71
536
1.49
1.93
12.1
5.7
—
—
—
0
0
78
601
1.48
1.92
5.6
3.2
6.74
7.48
mmol/l
0.67
72
498
149
1301
1.51
1.92
5.2
4.4
15.06
15.04
pmol/l
0.04
135
1159
7
22
3.25
1.89
1.6
1.4
—
—
—
0
0
43
605
0.64
1.89
4.3
3.5
—
—
—
0
0
100
812
1.44
1.86
4.0
3.0
—
—
estimate
—
0
0
12
53
2.34
1.84
1.2
1.1
—
—
—
0
0
95
765
1.44
1.84
4.7
4.3
40.72
39.82
ng/l
0.03
69
572
73
560
1.47
1.82
1.7
1.7
21.67
21.35
nmol/l
0.03
65
454
96
776
1.44
1.82
5.7
3.8
6.49
6.26
ph
1.44
49
421
34
221
1.64
1.77
2.3
1.6
—
—
—
0
0
27
165
1.73
1.75
6.9
5.1
0.23
0.00
%
1.09
13
51
28
173
1.71
1.75
2.5
1.6
—
—
—
0
0
139
1210
1.44
1.71
7.7
4.8
—
2.34
—
0
6
74
575
1.44
1.71
5.1
3.3
60.74
51.99
mg/l
0.14
53
377
12
55
2.25
1.71
8.4
4.0
1.13
2.70
ratio
—
5
31
10
41
2.51
1.67
1.7
1.3
—
—
—
0
0
5
14
3.63
1.62
1.0
1.2
121.80
102.29
pmol/l
—
5
14
118
1006
1.40
1.58
14.5
9.9
4.05
4.24
e9/l
0.47
108
875
7
27
2.65
1.53
1.6
1.0
—
—
—
0
0
83
670
1.40
1.52
2.5
2.1
—
—
—
0
0
25
156
1.68
1.52
6.1
4.6
0.17
0.42
%
1.12
12
53
9
38
2.43
1.47
1.2
1.7
4.31
3.79
mmol/l
—
9
38
13
66
2.03
1.47
1.6
3.0
432.43
217.17
mg/l
—
7
24
9
40
2.31
1.42
2.9
2.2
—
—
—
0
0
89
736
1.36
1.39
5.8
4.1
0.00
0.03
estimate
0.78
20
167
25
161
1.63
1.36
6.2
4.8
0.08
0.15
%
0.28
12
53
152
1370
1.40
1.36
33.8
22.1
13.84
13.78
%
0.25
152
1355
14
76
1.90
1.33
2.6
1.9
—
—
—
0
0
23
146
1.65
1.33
1.1
1.4
—
—
—
0
0
12
62
1.99
1.30
3.1
2.5
21.33
20.70
s
0.34
12
56
63
497
1.38
1.30
3.1
2.2
2.62
3.08
mg/l
0.54
58
436
54
415
1.41
1.30
8.4
4.3
1.02
1.02
kg/l
0.66
40
264
10
48
2.14
1.30
1.3
1.6
434.40
472.33
mg/l
—
10
48
5
18
2.82
1.29
1.2
1.1
—
—
—
0
0
99
841
1.34
1.27
2.3
2.1
95.17
97.49
pmol/l
0.17
57
403
8
36
2.27
1.25
1.3
1.1
—
—
—
0
0
24
158
1.59
1.21
2.3
2.2
0.21
0.21
g/l
0.05
24
145
12
64
1.93
1.20
24.9
14.4
—
—
—
0
0
8
38
2.15
1.20
4.1
2.7
1.17
1.21
mmol/l
—
8
38
8
38
2.15
1.20
4.1
2.7
102.75
105.92
mmol/l
—
8
38
8
38
2.15
1.20
4.1
2.7
4.21
4.04
mmol/l
—
8
38
62
497
1.35
1.15
5.3
3.4
—
0.00
—
0
15
5
21
2.41
1.09
1.0
1.9
91.36
89.09
%
—
5
21
178
1670
1.44
1.08
27.8
17.2
24.56
25.32
mg/l
0.11
153
1379
25
172
1.52
1.06
6.2
4.7
0.17
0.90
%
3.30
12
64
58
466
1.34
1.06
1.3
1.4
—
—
—
0
0
82
694
1.30
1.03
6.8
4.0
132.47
116.70
e6/l
0.10
60
487
66
544
1.31
1.01
6.6
4.1
0.00
0.01
estimate
0.50
27
186
50
398
1.34
0.97
7.9
5.5
—
—
—
0
0
55
448
1.31
0.91
7.2
3.8
89.91
88.39
%
0.14
55
442
79
675
1.27
0.91
4.0
3.1
2.34
2.35
mmol/l
0.43
70
609
10
56
1.83
0.89
4.7
2.6
24.65
24.96
mmol/l
—
10
49
8
44
1.85
0.87
1.3
1.6
3.75
35.32
e6/l
—
8
31
18
121
1.53
0.86
7.9
2.8
0.97
1.26
%
1.31
18
121
8
45
1.81
0.85
1.4
1.7
888.88
147.94
e6/l
—
8
33
10
57
1.79
0.85
7.1
2.8
1.71
1.46
mg/l
—
10
46
28
207
1.41
0.85
11.9
4.1
7.38
7.38
ph
0.43
20
133
30
226
1.38
0.82
9.3
6.1
0.33
1.02
mmol/l
0.32
22
185
31
235
1.37
0.82
8.9
5.9
7.44
7.42
ph
0.80
18
137
7
123
0.55
0.81
1.0
1.4
—
—
—
0
0
6
33
1.84
0.79
8.8
1.8
—
—
—
0
0
6
34
1.79
0.77
5.5
2.3
10.50
10.50
mmol/l
—
6
34
67
575
1.24
0.73
3.9
2.6
—
—
—
0
0
9
143
0.61
0.72
1.2
1.5
—
—
—
0
0
5
26
1.95
0.71
13.8
1.3
—
—
—
0
0
5
26
1.95
0.71
1.2
1.0
—
—
—
0
0
146
1362
1.24
0.70
36.8
23.0
331.53
331.36
g/l
0.09
146
1357
7
42
1.69
0.69
2.6
2.5
—
—
—
0
0
178
1701
1.31
0.68
23.6
15.4
—
—
—
0
0
63
541
1.24
0.68
6.0
3.7
0.00
0.00
estimate
-0.00
22
166
14
95
1.51
0.66
14.2
4.3
0.84
0.83
%
0.02
14
90
15
210
0.69
0.65
3.6
2.3
90.40
132.50
ug/g
—
10
168
20
148
1.39
0.62
3.7
3.1
—
—
—
0
0
5
30
1.68
0.62
3.8
1.4
—
—
—
0
0
5
30
1.68
0.62
3.8
1.4
—
—
—
0
0
5
30
1.68
0.62
3.8
1.4
—
—
—
0
0
5
30
1.68
0.62
3.8
1.4
—
—
—
0
0
23
175
1.35
0.61
1.6
2.5
5.97
5.30
ug/l
0.14
23
152
49
414
1.24
0.61
2.2
1.8
1.38
1.42
mg/l
0.04
40
336
0
20
0.00
0.60
0.0
1.7
—
8.27
—
0
20
50
424
1.24
0.60
6.4
4.0
—
0.33
—
0
6
6
36
1.69
0.57
1.5
2.3
10.92
9.53
pmol/l
—
6
36
16
116
1.41
0.56
5.4
2.5
5.49
5.02
kpa
0.50
16
108
70
620
1.19
0.55
5.6
3.3
29.13
141.91
e6/l
0.54
61
469
77
688
1.19
0.55
2.4
2.0
1.44
1.30
mmol/l
0.70
66
561
9
62
1.47
0.54
11.8
5.9
—
—
—
0
0
6
39
1.55
0.53
11.7
1.2
—
—
—
0
0
9
65
1.40
0.51
1.1
1.1
—
—
—
0
0
165
1580
1.21
0.49
9.1
6.7
41.51
39.87
mmol/mol
1.13
156
1470
11
76
1.47
0.49
6.9
2.4
—
—
—
0
0
14
102
1.40
0.48
14.5
4.2
1.54
1.46
%
0.25
14
96
7
47
1.51
0.48
10.1
1.3
—
—
—
0
0
7
47
1.51
0.48
10.1
1.3
—
—
—
0
0
7
48
1.47
0.47
10.1
1.3
—
—
—
0
0
7
48
1.47
0.47
10.1
1.3
—
—
—
0
0
7
49
1.44
0.46
10.4
1.3
—
—
—
0
0
36
306
1.21
0.43
1.4
1.3
62.45
45.33
iu/ml
0.22
11
97
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
2.8
—
—
—
0
0
17
214
0.78
0.40
1.3
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
37.04
—
0
19
5
37
1.36
0.37
4.2
3.0
4.60
5.03
kpa
—
5
37
5
37
1.36
0.37
4.2
3.0
7.92
7.93
kpa
—
5
37
6
44
1.37
0.34
1.3
1.3
67.38
405.12
pmol/l
—
6
44
34
298
1.17
0.31
5.0
3.1
1.96
3.04
e6/l
0.56
22
149
59
539
1.13
0.31
5.3
3.2
0.17
0.35
e6/l
1.55
51
395
45
404
1.15
0.30
1.8
1.9
431.03
445.62
pmol/l
0.11
38
333
18
216
0.82
0.30
2.6
3.9
2.33
40.52
ug/l
0.62
12
174
10
76
1.33
0.28
2.8
1.5
0.52
0.29
mg/l
—
5
30
160
1552
1.13
0.28
4.9
4.4
1.24
1.24
mmol/l
0.03
149
1401
160
1553
1.13
0.28
6.9
5.5
2.02
1.97
mu/l
0.20
152
1399
8
66
1.22
0.27
3.9
3.2
—
—
—
0
0
22
188
1.19
0.26
1.4
2.0
403.00
384.48
nmol/l
0.23
22
172
21
242
0.85
0.23
1.6
1.2
—
—
—
0
0
24
210
1.16
0.23
10.3
6.2
95.84
95.64
%
0.08
24
204
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
7.45
—
0
11
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
166
1626
1.10
0.19
5.9
5.3
4.30
4.53
mmol/l
2.46
157
1487
56
526
1.09
0.18
4.9
5.6
5.06
2.66
ug/l
0.39
50
468
169
1659
1.10
0.17
6.8
6.0
2.38
2.60
mmol/l
3.38
159
1515
12
141
0.84
0.17
3.8
1.6
—
—
—
0
0
14
120
1.18
0.17
7.8
5.8
23.23
24.87
mmol/l
0.98
14
120
16
139
1.16
0.17
1.3
1.2
—
—
—
0
0
7
89
0.78
0.15
2.6
2.7
—
—
—
0
0
39
365
1.08
0.13
2.3
1.5
2.61
2.58
g/l
0.02
29
198
19
171
1.12
0.13
15.9
6.7
—
—
—
0
0
24
220
1.10
0.12
1.7
1.3
—
—
—
0
0
34
318
1.08
0.12
3.3
3.3
0.54
0.81
ug/l
1.78
24
201
164
1616
1.07
0.11
5.7
5.1
1.46
1.48
mmol/l
0.21
155
1468
13
115
1.14
0.11
1.7
1.3
—
—
—
0
0
39
411
0.94
0.10
1.3
1.3
0.79
2.21
u/ml
—
7
108
5
44
1.14
0.10
6.8
2.6
54.20
60.84
%
—
5
44
160
1621
0.94
0.09
6.4
5.3
6.17
6.00
mmol/l
0.88
153
1468
26
277
0.93
0.08
1.5
1.3
1.31
12.74
u/ml
—
8
98
6
57
1.05
0.08
4.3
2.9
7.42
7.41
ph
—
6
57
14
153
0.91
0.07
1.8
1.8
—
—
—
0
0
9
84
1.07
0.07
1.2
1.3
—
—
—
0
0
50
483
1.05
0.07
4.0
2.9
361.09
349.87
umol/l
0.30
44
404
13
140
0.92
0.04
3.2
4.2
—
—
—
0
0
15
156
0.96
0.00
9.9
4.0
7.34
7.33
ph
0.12
15
108
10
99
1.01
0.00
1.1
1.3
55.19
335.33
u/ml
—
10
94
22
223
0.98
0.00
2.8
2.5
5.32
8.25
umol/l
1.13
22
193
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.0
1.3
0.21
0.23
g/l
—
5
55
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
37.74
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.34
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
7.76
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
63.25
—
0
8

Mortality – FinRegistry

Association

Association between endpoint H7_OTHENDOPHTHALMITIS and mortality.

Females

Parameter HR [95% CI] p-value
H7_OTHENDOPHTHALMITIS 1.387 [1.15, 1.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 280 out of 691 females with H7_OTHENDOPHTHALMITIS died.

Males

Parameter HR [95% CI] p-value
H7_OTHENDOPHTHALMITIS 1.786 [1.39, 2.3] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 230 out of 557 males with H7_OTHENDOPHTHALMITIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_OTHENDOPHTHALMITIS.

N-year risk Females Males
1 0.091% 0.253%
5 0.739% 1.803%
10 1.913% 4.433%
15 3.556% 8.403%
20 6.099% 13.372%

Relationships between endpoints

Index endpoint: H7_OTHENDOPHTHALMITIS – Other endophthalmitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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