No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
185 |
4. Check minimum number of eventsNone |
185 |
5. Include endpointsNone |
185 |
6. Filter based on genotype QC (FinnGen only) |
160 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D80
- Name in latin
- Deficientia selectiva immunoglobulini A
Similar endpoints
↥List of similar endpoints to
Selective deficiency of immunoglobulin A [IgA]y
based on the number of shared cases.
Similar with more cases:
- Immunodeficiency with predominantly antibody defects
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1030 | 548 | 479 |
| Only index persons | 873 | 467 | 406 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 23.14 | 26.92 | 18.74 |
| Only index persons | 27.90 | 32.01 | 23.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 160 | 99 | 61 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | 39.13 | 37.13 | 42.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 168
- Matched controls
- 1680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
200.7
150
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
16.1
36.8
34
26
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
34.6
32
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.4
24.6
115
483
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
24.6
23
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
24.6
23
*
2790B
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI A]
+∞
24.6
23
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
23.5
22
*
J01MA14
ATC
moxifloxacin; systemic
7.1
23.4
41
73
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.0
21.5
29
38
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
21.3
20
*
ZX120
NOMESCO Finland
Intravenous
6.2
21.3
43
88
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.3
19.3
75
263
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.1
19.0
50
129
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
6.2
18.4
36
71
J01MA12
ATC
levofloxacin; systemic
4.8
17.9
51
140
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.2
17.8
66
222
H02AB06
ATC
prednisolone; systemic
4.1
17.2
111
543
TPH04
NOMESCO Finland
Cathetrisation of vein
4.2
17.2
63
209
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
15.9
15
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
7.2
15.5
25
40
R03DC03
ATC
montelukast; oral
3.9
14.1
53
176
H02AB07
ATC
prednisone; oral
4.4
13.1
38
104
Z3231
NOMESCO Finland
Registered nurse
3.3
13.1
75
326
M05BA04
ATC
alendronic acid; oral
6.7
13.0
22
37
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.6
12.0
52
188
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.2
12.0
37
106
6BA02, ,
NOMESCO Finland
70.0
11.8
13
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.0
11.7
22
41
ZXE10
NOMESCO Finland
More than one and less than three hours
3.0
11.2
77
366
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.2
11.1
25
55
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.2
11.0
33
92
J47
ICD-10 Finland
Bronchiectasis
17.5
10.6
16
10
J45.9
ICD-10 Finland
Asthma, unspecified
3.3
10.4
50
192
R50.9
ICD-10 Finland
Fever, unspecified
3.4
10.2
46
169
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.4
10.2
28
73
J01FA06
ATC
roxithromycin; oral
2.8
10.0
84
439
SPAT1262
SPAT
Handing over of treatment supplies
3.6
9.7
37
122
P01BA02
ATC
hydroxychloroquine; oral
4.3
9.7
27
71
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
8.9
9.7
20
25
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
12.5
9.3
16
14
WX892
NOMESCO Finland
Monitored bed care
4.7
9.3
23
55
K90.0
ICD-10 Finland
Coeliac disease
8.8
9.1
19
24
J01FA15
ATC
telithromycin; oral
4.1
9.1
28
79
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.7
9.0
22
52
J01MA02
ATC
ciprofloxacin; systemic
2.7
9.0
75
386
C03CA01
ATC
furosemide; systemic
3.1
8.8
45
177
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
52.8
8.8
10
*
L04AX03
ATC
methotrexate; systemic
3.8
8.7
29
87
L04AA13
ATC
[U] leflunomide
11.6
8.5
15
14
R03BA02
ATC
budesonide; inhalant
3.0
8.5
47
194
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.5
8.4
22
55
Z3229
NOMESCO Finland
Other healthcare associate professional
4.5
8.4
22
55
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.0
8.4
26
74
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.8
8.2
27
80
J01FA09
ATC
clarithromycin; systemic
2.6
8.1
72
377
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
7.9
49
214
A02BC02
ATC
pantoprazole; systemic
2.7
7.7
119
802
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.5
7.7
68
354
J01FF01
ATC
clindamycin; systemic
2.6
7.7
58
280
R03AC02
ATC
salbutamol; inhalant
2.6
7.6
115
765
J01FA01
ATC
erythromycin; systemic
3.1
7.6
37
141
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
7.6
50
225
L01BA01
ATC
methotrexate; systemic
8.3
7.6
16
21
J01DA06
ATC
[U] cefuroxime
3.0
7.4
37
143
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
+∞
7.3
7
*
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
7.3
7
*
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
7.3
7
*
R01AD05
ATC
budesonide; nasal
4.0
7.3
22
61
Z2221
NOMESCO Finland
Medical doctor
2.5
7.2
64
332
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.4
7.2
29
98
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
7.2
60
303
R06.2
ICD-10 Finland
Wheezing
6.4
7.1
18
31
J01AA02
ATC
doxycycline; systemic
2.9
7.1
135
987
WX002
NOMESCO Finland
Sedation and analgesia
3.0
7.1
37
146
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.3
7.1
30
105
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
7.0
21
58
XQ800
NOMESCO Finland
Prick test
3.7
7.0
24
73
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.7
7.0
24
73
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.3
7.0
29
100
L04AX01
ATC
azathioprine; systemic
4.6
6.9
17
40
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
6.9
113
765
A07EC01
ATC
sulfasalazine; oral, rectal
3.8
6.8
22
64
WW200
NOMESCO Finland
Immunization
9.3
6.7
13
15
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
7.4
6.7
15
22
R03BA05
ATC
fluticasone; inhalant
2.6
6.6
47
218
R01AD12
ATC
fluticasone furoate; nasal
2.3
6.5
73
417
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
6.5
71
401
L04AC07
ATC
tocilizumab; parenteral
72.5
6.5
7
*
H02AB04
ATC
methylprednisolone; systemic
3.0
6.4
31
117
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
11.7
6.4
11
10
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.8
6.4
20
57
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.9
6.4
34
136
Z3226
NOMESCO Finland
Physiotherapist
2.6
6.3
43
195
L88
ICPC
Rheumatoid/seropositive arthritis
6.2
6.3
16
28
R05
ICD-10 Finland
Cough
2.5
6.3
47
223
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
27.8
6.3
8
*
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
6.3
6
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
6.3
25
84
UJF32
NOMESCO Finland
Coloscopy
2.6
6.2
45
210
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.4
6.2
16
39
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.9
6.1
31
120
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
10.6
6.1
11
11
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
6.1
24
80
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
6.1
20
59
N03AX16
ATC
[U] pregabalin
2.5
6.1
44
206
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
53
122
5.89
23.31
1.7
1.2
146.53
417.51
u/ml
0.60
42
114
50
113
5.88
22.36
2.0
1.1
72.29
—
u/ml
—
14
0
24
5
55.57
20.77
3.7
1.4
545.96
1023.00
u/ml
—
24
5
26
9
33.82
20.34
1.8
1.3
—
—
—
0
0
25
8
36.35
19.91
1.8
1.4
13.44
6.75
%
—
25
8
146
878
6.06
16.84
17.5
11.3
3.92
3.91
e9/l
0.02
137
759
117
646
3.67
14.03
4.1
2.7
73.68
74.34
nmol/l
0.09
112
596
107
564
3.47
13.72
8.1
5.6
36.88
36.75
g/l
0.08
99
546
16
5
35.09
12.82
1.9
1.2
13.69
10.60
u/l
—
16
5
112
636
3.28
12.13
12.4
9.1
1.21
1.21
mmol/l
0.16
98
564
16
7
25.06
11.81
2.1
1.1
24.44
27.43
%
—
16
7
55
215
3.32
11.17
2.5
1.7
—
—
—
0
0
56
224
3.25
10.92
4.4
2.6
13.19
14.32
umol/l
0.56
56
209
14
5
30.31
10.91
1.0
1.0
94.00
81.60
%
—
14
5
31
83
4.35
10.90
2.7
1.7
—
—
—
0
0
80
417
2.75
9.42
5.7
2.9
0.21
0.35
e6/l
0.73
59
301
19
43
4.85
8.13
1.4
1.4
—
—
—
0
0
20
51
4.32
7.40
1.3
1.4
—
—
—
0
0
40
162
2.93
7.37
2.5
1.5
—
—
—
0
0
50
240
2.54
6.58
2.7
2.7
2.72
2.63
e6/l
0.02
20
104
19
51
4.07
6.57
1.4
1.4
38.72
8.99
u/ml
—
5
13
19
51
4.07
6.57
1.4
1.4
1.76
2.85
u/ml
—
5
8
66
370
2.29
6.08
2.0
1.5
19.54
22.05
nmol/l
0.67
56
323
16
40
4.32
6.05
1.8
1.7
—
—
—
0
0
26
92
3.16
5.99
6.0
4.7
1.10
1.24
mmol/l
0.06
20
69
50
253
2.39
5.80
2.7
2.5
0.73
0.87
e6/l
0.21
20
118
35
150
2.68
5.73
2.7
1.5
—
—
—
0
0
15
28
5.77
5.69
1.5
1.8
—
—
—
0
0
37
172
2.48
5.11
2.1
1.6
1154.45
1186.48
nmol/l
0.07
31
129
59
338
2.15
5.00
2.0
2.0
1.37
1.02
mg/l
0.47
45
261
10
13
8.10
4.92
3.6
2.0
—
—
—
0
0
15
34
4.74
4.88
1.9
2.9
—
—
—
0
0
109
790
2.08
4.84
7.2
3.5
47.36
8.87
estimate
0.37
28
183
26
104
2.77
4.82
4.0
6.7
23.94
24.53
mmol/l
0.40
26
104
14
30
4.99
4.80
2.4
4.4
0.00
0.00
g/l
-0.00
14
30
53
295
2.16
4.80
1.3
1.3
10.54
24.10
iu/ml
1.80
11
90
14
31
4.83
4.68
1.6
1.3
—
—
—
0
0
14
31
4.83
4.68
1.6
1.3
—
—
—
0
0
27
112
2.68
4.68
7.1
10.1
22.94
25.50
mmol/l
4.57
27
112
9
11
8.57
4.62
4.9
3.3
—
—
—
0
0
10
15
7.01
4.54
3.6
1.9
—
—
—
0
0
20
72
3.02
4.47
2.0
3.2
6.49
4.88
iu/ml
—
10
18
14
33
4.53
4.44
1.4
1.4
349.56
353.07
ug/g
—
8
18
83
560
1.95
4.36
2.4
1.9
95.15
98.29
pmol/l
0.20
46
288
107
787
1.99
4.36
7.3
3.4
0.00
0.00
estimate
-0.00
26
181
12
25
5.08
4.27
2.5
1.1
—
—
—
0
0
107
794
1.96
4.16
7.4
3.6
0.00
0.02
estimate
0.50
25
171
17
59
3.09
4.03
1.6
1.3
—
—
—
0
0
12
27
4.70
4.02
1.8
2.3
—
—
—
0
0
11
23
5.04
3.94
8.5
4.3
21.09
10.51
pmol/l
1.01
11
23
18
66
2.93
3.90
2.3
1.6
—
—
—
0
0
64
409
1.91
3.84
8.2
3.7
0.00
0.01
estimate
0.50
25
174
14
39
3.82
3.80
1.9
1.7
—
—
—
0
0
18
67
2.89
3.80
1.3
1.3
—
—
—
0
0
48
280
2.00
3.74
1.3
1.3
1.90
6.23
u/ml
1.16
27
114
30
146
2.28
3.70
6.6
6.5
0.88
1.78
mmol/l
0.50
23
124
13
37
3.72
3.49
3.4
1.5
—
—
—
0
0
156
1369
2.95
3.49
27.5
13.0
87.44
88.86
ml/min/173m2
0.28
149
1243
18
71
2.72
3.42
1.3
1.3
—
—
—
0
0
69
467
1.81
3.37
5.9
3.6
247.58
34.12
ng/l
0.61
36
277
12
33
3.83
3.37
2.3
1.5
—
—
—
0
0
26
124
2.30
3.36
5.4
3.1
—
—
—
0
0
17
66
2.75
3.33
2.0
1.4
—
—
—
0
0
11
29
3.98
3.25
2.6
4.4
0.00
0.00
g/l
-0.00
11
29
8
16
5.19
3.09
2.5
1.7
—
—
—
0
0
6
8
7.72
3.08
1.5
2.0
—
—
—
0
0
6
8
7.72
3.08
1.5
2.0
—
—
—
0
0
6
8
7.72
3.08
1.5
2.0
—
—
—
0
0
6
8
7.72
3.08
1.5
2.0
—
—
—
0
0
8
17
4.88
2.95
2.5
1.6
—
—
—
0
0
8
17
4.88
2.95
2.5
1.6
—
—
—
0
0
8
17
4.88
2.95
2.5
1.6
—
—
—
0
0
8
17
4.88
2.95
2.5
1.6
—
—
—
0
0
8
17
4.88
2.95
2.5
1.6
—
—
—
0
0
12
38
3.32
2.92
2.0
1.2
—
—
—
0
0
80
584
1.71
2.90
7.8
3.3
0.00
0.02
estimate
0.74
25
152
6
9
6.86
2.89
1.8
1.9
—
—
—
0
0
8
18
4.61
2.83
1.4
1.8
—
—
—
0
0
9
23
4.07
2.82
1.4
1.5
—
—
—
0
0
62
425
1.73
2.81
2.0
1.9
—
—
—
0
0
5
6
8.54
2.76
1.4
2.2
—
—
—
0
0
5
6
8.54
2.76
1.4
2.2
—
—
—
0
0
5
6
8.54
2.76
1.4
2.2
—
—
—
0
0
136
1164
1.88
2.67
6.4
4.4
14.75
14.57
pmol/l
0.43
129
1078
28
152
2.01
2.62
3.5
2.0
—
—
—
0
0
51
337
1.74
2.60
4.1
3.2
360.91
336.10
umol/l
0.93
45
313
14
56
2.64
2.60
3.8
3.8
23.76
24.63
mmol/l
0.40
14
56
10
31
3.36
2.56
1.5
1.7
—
—
—
0
0
10
32
3.26
2.48
1.2
1.2
—
1.09
—
0
14
6
12
5.14
2.42
1.5
1.9
—
—
—
0
0
6
12
5.14
2.42
1.5
1.9
—
—
—
0
0
6
12
5.14
2.42
1.5
1.9
—
—
—
0
0
8
22
3.76
2.39
1.6
1.7
—
—
—
0
0
9
28
3.34
2.34
1.7
1.6
—
—
—
0
0
63
452
1.63
2.33
8.3
2.9
0.00
0.01
estimate
0.50
24
148
30
174
1.88
2.33
6.9
8.9
104.57
104.33
mmol/l
0.09
30
174
6
13
4.74
2.29
2.8
1.0
—
—
—
0
0
49
332
1.67
2.26
3.0
2.3
—
—
—
0
0
5
9
5.69
2.23
1.6
2.7
—
—
—
0
0
5
9
5.69
2.23
1.6
2.7
—
—
—
0
0
8
24
3.45
2.21
1.7
1.4
—
—
—
0
0
6
14
4.40
2.17
2.0
1.1
—
—
—
0
0
6
14
4.40
2.17
2.8
1.1
—
—
—
0
0
12
49
2.56
2.15
1.9
1.9
—
—
—
0
0
86
676
1.56
2.12
3.5
2.8
—
—
estimate
—
0
0
6
15
4.11
2.06
1.2
1.3
—
—
—
0
0
37
238
1.71
2.05
2.9
2.9
2.42
2.44
mmol/l
0.42
32
219
13
58
2.35
1.96
2.2
3.8
89.23
97.74
%
0.87
13
58
20
107
1.99
1.96
6.8
10.3
1.61
1.32
mmol/l
0.43
20
107
30
184
1.77
1.96
3.5
2.1
—
—
—
0
0
47
326
1.61
1.95
4.8
3.4
1478.75
820.02
ng/l
0.79
42
274
130
1141
1.62
1.83
5.1
3.7
—
—
—
0
0
14
67
2.19
1.82
12.8
4.7
54.06
53.41
%
0.03
14
67
6
18
3.42
1.76
1.5
1.5
—
—
—
0
0
11
48
2.38
1.74
3.1
1.7
—
—
—
0
0
19
105
1.91
1.71
1.5
1.2
—
31.87
—
0
9
5
14
3.65
1.62
1.4
1.9
—
—
—
0
0
5
15
3.40
1.53
1.6
1.3
—
—
—
0
0
5
15
3.40
1.53
1.6
1.1
—
—
—
0
0
9
37
2.51
1.50
1.9
1.7
—
—
—
0
0
5
16
3.19
1.45
1.6
1.3
—
—
—
0
0
5
16
3.19
1.45
1.2
2.3
0.52
0.86
mmol/l
—
5
16
7
29
2.47
1.41
6.9
3.2
17.13
16.48
%
—
7
29
45
332
1.49
1.40
4.6
3.3
1.02
1.02
kg/l
0.46
32
218
21
129
1.72
1.38
6.9
12.5
0.86
1.19
mmol/l
0.11
16
107
20
122
1.73
1.34
1.8
1.3
—
—
—
0
0
14
79
1.84
1.21
2.6
5.5
0.71
0.62
%
0.50
14
79
6
26
2.35
1.19
1.0
1.0
—
—
—
0
0
6
26
2.35
1.19
3.3
3.9
21.68
28.15
nmol/l
—
6
21
14
80
1.82
1.17
7.6
11.7
91.16
93.60
%
0.45
14
80
12
65
1.91
1.16
1.8
1.6
—
—
—
0
0
75
632
1.34
1.05
1.8
1.9
1.42
1.38
mmol/l
0.13
60
554
9
49
1.88
1.00
1.2
1.1
—
—
—
0
0
5
23
2.21
0.98
2.4
1.9
—
—
—
0
0
5
23
2.21
0.98
1.4
1.4
—
—
—
0
0
152
1439
1.59
0.96
5.9
5.0
2.65
2.81
mmol/l
1.33
145
1359
19
126
1.57
0.96
1.4
1.3
38.78
122.51
u/ml
—
9
47
14
89
1.63
0.84
1.9
1.6
289.00
329.60
mu/l
0.42
14
79
8
47
1.74
0.82
1.3
1.1
—
—
—
0
0
49
403
1.30
0.79
7.7
4.1
15.34
9.74
mg/mmol
0.25
36
254
5
25
2.03
0.73
3.2
1.4
383.20
285.45
mu/l
—
5
20
15
212
0.68
0.69
1.4
2.0
4.14
3.45
ratio
—
10
175
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
13
92
1.45
0.52
1.2
1.3
—
—
—
0
0
6
40
1.52
0.52
1.5
2.2
0.50
167.57
e6/l
—
6
30
148
1426
1.32
0.50
5.5
4.5
1.42
1.45
mmol/l
0.36
141
1342
11
154
0.69
0.49
1.3
1.8
3.32
3.43
mmol/l
—
6
116
30
247
1.26
0.48
4.1
3.4
351.79
376.47
ng/l
0.03
19
156
15
112
1.37
0.46
1.0
1.0
—
—
—
0
0
7
51
1.39
0.44
16.0
5.2
22.51
24.47
mmol/l
—
7
51
5
32
1.58
0.42
2.4
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
142
1372
1.23
0.38
5.2
4.2
5.86
5.75
mmol/l
0.45
135
1283
139
1349
1.18
0.29
4.9
3.9
1.31
1.27
mmol/l
0.23
132
1262
115
1103
1.14
0.28
4.8
3.5
47.17
41.88
u/l
0.29
109
1067
8
64
1.26
0.28
1.0
1.4
—
—
—
0
0
30
265
1.16
0.26
3.6
3.9
24.33
23.32
%
0.11
15
103
0
10
0.00
0.21
0.0
1.0
—
8.50
—
0
10
0
14
0.00
0.20
0.0
1.2
—
208.06
—
0
14
5
67
0.74
0.17
1.6
1.5
—
—
—
0
0
23
206
1.13
0.17
3.2
2.8
0.75
0.76
ug/l
0.01
17
115
6
76
0.78
0.16
1.7
1.8
—
—
—
0
0
31
288
1.09
0.13
3.7
2.1
—
—
—
0
0
33
313
1.07
0.08
3.7
2.3
—
—
—
0
0
13
123
1.06
0.01
11.5
6.3
—
—
—
0
0
28
277
1.01
0.00
2.2
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
4.69
—
0
6
0
6
0.00
-0.00
0.0
2.3
—
10.32
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
52
0.96
-0.00
1.4
1.5
76.08
53.74
ug/l
—
5
52
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.3
—
0.89
—
0
9
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
131
1310
1.00
-0.00
7.9
5.5
39.13
38.29
mmol/mol
0.41
126
1250
5
52
0.96
-0.00
6.2
2.5
6.38
4.59
umol/l
—
5
41
Mortality – FinRegistry
↥Association
Association between endpoint D3_DEF_IIGA and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_DEF_IIGA.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_DEF_IIGA – Selective deficiency of immunoglobulin A [IgA]y
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data