Mesial bite

K11_MESIAL_BITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.21
  • Hospital discharge: ICD-10 K07.21
  • Cause of death: ICD-10 K07.21

3 out of 7 registries used, show all original rules.

412

4. Check minimum number of events

None

412

5. Include endpoints

None

412

6. Filter based on genotype QC (FinnGen only)

370

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8284 4430 3837
Only index persons 7332 3977 3355
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.11
Only index persons 0.14 0.15 0.13
Median age at first event (years)
Whole population 11.24 11.42 10.94
Only index persons 12.14 12.32 11.94

-FinnGen-

Key figures

All Female Male
Number of individuals 370 259 111
Unadjusted period prevalence (%) 0.08 0.09 0.05
Median age at first event (years) 27.57 27.91 26.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
389
Matched controls
3890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
+∞
307.7
389
*
K07.24
ICD-10 Finland
Open bite
39.5
185.9
121
44
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
12.7
103.4
118
129
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
58.1
96.5
55
11
K07.14
ICD-10 Finland
Retrognaty, maxillary
47.7
84.1
50
12
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
8.6
76.1
118
187
SBB10
NOMESCO Finland
Dental impressions
6.1
69.6
190
526
EB1MA
NOMESCO Finland
Cephalometry with X-ray
7.2
62.1
113
210
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
6.3
46.4
91
179
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
5.3
42.4
106
259
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
7.2
39.1
64
104
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
5.0
38.7
102
259
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
5.3
37.6
89
206
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
6.8
35.0
60
102
EEC05
NOMESCO Finland
Le Fort I osteotomy
131.8
34.3
36
*
K07.13
ICD-10 Finland
Retrognaty, mandibular
8.3
34.3
48
65
SJC10
NOMESCO Finland
Orthodontic band in one tooth
5.0
33.4
83
199
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
4.7
32.7
89
230
SAA04
NOMESCO Finland
Special examination of mouth
4.5
32.6
96
264
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
3.9
30.4
118
395
K07.60
ICD-10 Finland
Snapping jaw
5.3
30.0
68
150
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
4.3
30.0
92
260
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.2
26.0
82
235
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.6
25.7
105
360
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
6.4
25.5
45
78
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
3.9
25.2
88
271
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
24.5
252
1462
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.4
24.5
69
181
SAA03
NOMESCO Finland
Extended examination of mouth
3.1
23.6
278
1723
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
29.4
22.6
30
11
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
3.9
21.3
73
220
SXC05
NOMESCO Finland
Other oral or dental procedure
3.2
21.0
106
410
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
20.8
222
1275
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.2
19.2
93
349
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.6
18.1
68
217
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.9
17.4
55
156
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.3
17.2
73
252
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
3.1
16.7
82
309
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
3.2
16.1
72
256
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
35.4
13.6
17
5
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
5.6
12.9
25
47
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
2.8
12.3
67
265
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
4.3
12.1
32
79
SAA02
NOMESCO Finland
Basic examination of mouth
3.4
12.1
353
2890
OIKK, ,
NOMESCO Finland
2.7
11.9
72
300
K03.66
ICD-10 Finland
Tooth plaque
2.7
11.8
71
296
K07.10
ICD-10 Finland
Asymmetry of jaw
23.8
11.7
16
7
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
3.3
11.0
44
145
SAA01
NOMESCO Finland
Simple examination of mouth
2.8
11.0
341
2779
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
10.6
213
1450
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
5.1
10.4
22
45
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
2.9
10.1
50
187
K00.00
ICD-10 Finland
Hypodontia
4.5
10.0
25
59
D82
ICPC
Teeth/gum disease
2.0
9.8
204
1394
F45.8
ICD-10 Finland
Other somatoform disorders
2.7
9.3
52
207
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
37.6
9.1
11
*
WZA90
NOMESCO Finland
Other medical or dental certificate
2.0
8.8
138
850
SDA03
NOMESCO Finland
Periodontal treatment
1.9
8.5
185
1265
KAY20, ,
NOMESCO Finland
3.8
8.1
25
69
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.1
8.1
85
449
K03.64
ICD-10 Finland
Dental calculus supragingival
1.9
8.1
192
1342
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.9
8.0
132
821
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
6.3
8.0
20
33
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.0
7.8
108
632
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
25.6
7.6
10
*
EBA00
NOMESCO Finland
Extraction of tooth
1.8
7.5
190
1345
K03.00
ICD-10 Finland
Approximal wear
2.6
7.3
44
182
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
16.1
7.3
11
7
SPAT1310
SPAT
Counselling related to known health issue
1.8
7.1
150
1002
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
7.1
105
627
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.0
6.9
93
536
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
14.1
6.9
11
8
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
6.9
152
1026
SPAT1263
SPAT
Sampling
1.8
6.7
178
1264
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
12.5
6.6
11
9
EBB10
NOMESCO Finland
Insertion of dental implant
10.3
6.6
12
12
OIKH, ,
NOMESCO Finland
2.3
6.6
50
231
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
5.9
6.5
17
30
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
14.6
6.4
10
7
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
6.4
137
913
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
5.7
6.4
17
31
SFA00
NOMESCO Finland
Small restoration
2.1
6.3
64
332
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
18.4
6.3
9
5
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
2.5
6.3
42
183
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.1
6.3
60
305
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
27.1
6.2
8
*
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
6.5
6.2
15
24
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.7
6.1
175
1261
EBB15
NOMESCO Finland
Insertion of dental implant abutment
12.8
6.1
10
8
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
4.0
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
48
225
2.29
6.10
3.4
3.8
7.37
7.35
ph
0.33
34
164
51
259
2.12
5.33
2.6
2.1
13.35
12.14
nmol/l
0.39
46
243
23
81
2.96
5.18
1.6
1.3
345.28
318.67
mu/l
0.18
18
63
135
1007
1.52
3.65
2.6
2.5
—
—
—
0
0
9
23
3.98
2.79
1.4
1.1
149.74
173.19
pmol/l
—
9
23
53
339
1.65
2.73
1.4
1.6
1091.83
1163.46
nmol/l
0.22
32
257
36
206
1.82
2.72
1.8
1.8
7.56
8.07
u/l
0.14
26
165
48
311
1.62
2.36
1.3
1.4
—
—
—
0
0
296
2695
1.41
2.20
5.0
4.3
14.55
14.44
pmol/l
0.35
274
2464
51
344
1.56
2.13
1.2
1.2
—
—
—
0
0
252
2250
1.34
2.02
6.6
7.3
84.52
81.10
u/l
0.41
236
2125
332
3102
1.48
2.01
5.8
5.1
1.93
1.82
mu/l
1.14
311
2918
56
393
1.50
1.96
2.1
2.8
4.43
4.24
e9/l
0.08
44
355
0
51
0.00
1.90
0.0
1.3
—
—
—
0
0
55
388
1.49
1.89
1.7
1.6
—
—
—
0
0
9
34
2.69
1.87
1.3
1.6
0.47
0.48
e9/l
—
9
34
306
2833
1.38
1.81
4.5
3.8
5.68
5.62
mmol/l
0.30
283
2623
39
261
1.55
1.71
1.7
1.7
21.86
14.47
iu/l
0.92
33
214
0
48
0.00
1.71
0.0
1.3
—
—
—
0
0
6
20
3.03
1.58
1.2
1.1
16.83
8.20
mm/h
—
6
20
11
50
2.23
1.58
2.2
1.5
12.99
13.07
%
0.13
11
50
19
312
0.59
1.46
1.9
2.3
28.08
30.88
u/l
0.32
13
252
7
28
2.53
1.46
1.3
1.3
—
—
—
0
0
5
16
3.15
1.44
2.6
3.6
—
—
—
0
0
9
40
2.28
1.41
1.1
1.2
—
—
—
0
0
34
232
1.51
1.40
3.9
4.7
0.13
0.52
%
—
8
66
30
199
1.55
1.40
8.8
5.4
—
—
—
0
0
358
3446
1.49
1.32
10.6
10.0
—
—
—
0
0
26
381
0.66
1.24
1.2
1.3
—
—
—
0
0
46
342
1.39
1.23
1.2
1.3
119.64
152.64
u/ml
0.13
11
133
11
56
1.99
1.23
3.9
3.4
26.02
31.10
mg/l
—
5
40
35
248
1.45
1.22
8.4
5.2
7.41
7.41
ph
0.42
28
198
33
232
1.46
1.20
3.9
5.3
0.00
0.12
%
—
7
60
22
142
1.58
1.17
3.2
2.6
80.53
106.04
ng/l
0.28
17
134
89
738
1.27
1.14
2.0
2.1
172.72
260.53
u/l
0.46
79
701
34
245
1.42
1.10
3.9
5.1
0.38
0.79
%
—
8
75
209
1904
1.21
1.09
3.4
3.3
66.28
73.78
ug/l
0.46
198
1816
5
21
2.40
1.09
2.2
4.3
1.75
2.51
ug/l
—
5
21
59
468
1.31
1.06
1.3
1.6
433.72
16223194.86
pmol/l
0.50
46
413
121
1047
1.23
1.06
7.9
8.9
1.10
1.13
inr
0.51
100
865
7
34
2.08
1.03
1.0
1.2
—
—
—
0
0
103
879
1.23
1.03
2.6
2.7
54.75
60.62
u/l
0.54
89
812
14
223
0.61
0.99
1.4
1.3
—
—
—
0
0
37
277
1.37
0.98
2.4
1.9
0.00
0.05
estimate
—
5
66
0
29
0.00
0.98
0.0
2.9
—
0.18
—
0
15
134
1180
1.21
0.98
1.5
1.5
1.47
1.80
u/ml
0.20
26
283
32
235
1.39
0.95
4.3
5.4
0.17
0.09
%
—
6
56
131
1155
1.20
0.94
3.7
5.4
37.69
37.53
g/l
0.16
119
1096
104
1191
0.83
0.90
4.6
4.1
21.85
81.35
e6/l
2.52
74
786
11
181
0.60
0.90
1.5
1.6
—
—
—
0
0
6
31
1.95
0.84
2.7
6.2
—
—
—
0
0
165
1499
1.17
0.83
3.5
2.8
69.17
71.02
nmol/l
0.39
149
1398
32
416
0.75
0.82
1.3
1.8
—
—
—
0
0
69
811
0.82
0.78
4.1
3.9
7.38
7.39
ph
1.48
54
572
153
1388
1.17
0.77
8.6
8.4
1.22
1.22
mmol/l
0.47
131
1235
33
254
1.33
0.76
2.1
1.9
6.33
6.22
ph
0.26
18
166
18
253
0.70
0.74
2.8
2.7
0.63
0.75
ug/l
—
9
138
11
171
0.63
0.74
1.5
1.5
1.44
1.26
mm
—
6
130
128
1412
0.86
0.69
3.4
3.1
6.30
6.26
ph
0.16
67
776
5
27
1.86
0.68
2.8
1.8
35.20
42.57
mg/l
—
5
21
7
120
0.58
0.68
1.1
1.2
—
—
—
0
0
137
1243
1.16
0.68
8.5
8.3
1.23
1.22
mmol/l
1.28
124
1163
41
502
0.80
0.68
4.0
3.2
5.61
3.81
e6/l
0.39
23
234
127
1147
1.16
0.67
2.0
1.9
—
—
—
0
0
12
178
0.66
0.66
1.5
1.5
—
—
—
0
0
5
28
1.80
0.66
2.2
2.1
93.68
91.82
%
—
5
28
275
2626
1.16
0.66
5.6
4.7
37.36
37.23
mmol/mol
0.09
254
2502
77
670
1.19
0.64
4.4
4.2
10.85
10.07
mg/mmol
0.03
44
440
5
29
1.73
0.64
1.4
1.2
—
—
—
0
0
236
2235
1.14
0.62
3.4
3.4
59.36
34.32
u/l
0.87
228
2141
36
441
0.80
0.61
1.4
1.6
948.67
930.85
mu/l
0.05
28
386
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
2.0
—
39.00
—
0
22
34
417
0.80
0.58
1.8
1.8
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
1368.96
—
0
23
128
1168
1.14
0.58
5.5
7.0
—
—
—
0
0
297
2864
1.16
0.57
4.6
4.0
1.43
1.46
mmol/l
1.05
274
2716
5
86
0.58
0.57
7.4
9.8
1.46
1.56
%
—
5
79
148
1597
0.88
0.56
7.3
9.9
0.00
0.00
e9/l
0.50
124
1276
76
669
1.17
0.56
3.5
3.6
55.22
66.19
mg/l
0.11
39
452
299
2888
1.15
0.55
4.6
4.1
4.59
4.60
mmol/l
0.09
279
2751
9
60
1.51
0.54
1.8
1.7
—
—
—
0
0
9
60
1.51
0.54
1.8
1.7
—
—
—
0
0
9
60
1.51
0.54
1.8
1.7
—
—
—
0
0
9
60
1.51
0.54
1.8
1.7
—
—
—
0
0
34
413
0.81
0.54
1.6
1.8
—
—
—
0
0
34
413
0.81
0.54
1.6
1.8
—
—
—
0
0
108
979
1.14
0.54
3.5
3.5
8.45
8.63
mmol/l
0.15
92
872
76
856
0.86
0.54
4.3
3.5
0.08
0.29
e6/l
3.21
57
610
9
62
1.46
0.53
1.8
1.9
29.40
19.08
ng/l
—
9
62
6
40
1.51
0.52
3.2
2.3
1.15
1.74
mmol/l
—
6
40
70
617
1.16
0.51
2.5
2.6
119.88
97.81
ug/g
0.21
49
477
96
867
1.14
0.51
2.1
2.3
2.69
2.59
mg/l
0.18
85
747
24
300
0.79
0.50
1.7
2.1
—
—
—
0
0
48
411
1.19
0.49
1.3
1.2
—
—
—
0
0
208
1972
1.12
0.49
7.9
9.8
3.81
3.82
e9/l
0.03
181
1711
197
1865
1.11
0.47
5.9
7.4
0.19
0.18
e9/l
0.11
173
1651
97
881
1.13
0.47
2.6
2.8
15.87
24.84
ng/l
0.95
54
447
32
384
0.82
0.47
1.4
1.6
—
—
—
0
0
278
2684
1.13
0.46
3.9
3.5
1.15
1.19
mmol/l
0.51
253
2531
196
1857
1.11
0.46
5.9
7.0
2.04
2.04
e9/l
0.03
176
1658
33
391
0.83
0.43
1.6
1.8
—
—
—
0
0
298
2894
1.13
0.43
5.0
4.4
2.78
2.73
mmol/l
0.41
275
2751
180
1704
1.10
0.42
5.4
6.9
54.15
55.16
%
0.61
174
1641
109
1179
0.90
0.42
1.7
1.6
—
—
—
0
0
48
418
1.17
0.42
4.8
4.5
1.45
1.78
ug/l
0.44
39
371
90
984
0.89
0.42
4.2
3.5
21.29
37.84
e6/l
0.62
71
738
50
569
0.86
0.42
3.7
2.9
537.23
562.83
mosm/kgh2o
0.26
39
499
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
182
1726
1.10
0.41
5.6
7.1
31.34
30.71
%
0.32
176
1656
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
6.47
—
0
17
44
383
1.17
0.39
1.5
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
44
384
1.16
0.38
2.1
1.7
—
—
—
0
0
9
68
1.33
0.38
2.3
2.3
—
—
—
0
0
8
112
0.71
0.37
2.8
2.0
—
—
—
0
0
26
310
0.83
0.37
1.3
1.5
—
—
—
0
0
8
115
0.69
0.37
1.3
2.3
—
—
—
0
0
8
115
0.69
0.37
1.6
1.7
—
—
—
0
0
9
69
1.31
0.37
7.4
7.4
—
—
—
0
0
26
217
1.21
0.36
2.0
4.1
64.87
69.09
e9/l
0.29
21
147
5
79
0.63
0.36
1.4
1.1
—
—
—
0
0
12
156
0.76
0.35
1.1
1.1
—
—
—
0
0
346
3403
1.15
0.35
10.1
10.0
26.61
24.92
u/l
0.71
336
3313
175
1668
1.09
0.34
5.9
7.2
8.13
8.44
%
0.90
164
1582
17
136
1.26
0.34
1.1
1.1
—
0.57
—
0
12
10
133
0.75
0.34
1.3
1.4
—
—
—
0
0
104
970
1.10
0.33
2.7
3.2
2.37
2.37
mmol/l
0.33
91
890
23
273
0.83
0.32
6.3
7.6
24.28
23.85
mmol/l
0.42
23
273
156
1483
1.09
0.32
3.3
2.9
—
—
estimate
—
0
0
71
774
0.90
0.32
3.3
4.9
93.80
92.30
%
0.27
71
763
174
1662
1.08
0.32
6.0
7.2
0.66
0.65
%
0.01
162
1569
16
197
0.80
0.32
1.8
2.1
—
—
—
0
0
34
296
1.16
0.31
3.0
3.8
0.23
0.23
g/l
0.02
29
281
132
1248
1.09
0.31
2.5
2.5
—
—
—
0
0
17
138
1.24
0.31
1.8
1.7
—
—
—
0
0
83
768
1.10
0.31
1.6
1.5
20.54
20.78
nmol/l
0.06
70
673
30
259
1.17
0.31
1.8
1.6
256.53
320.98
mu/l
1.60
30
240
7
54
1.30
0.30
1.3
1.1
—
—
—
0
0
92
857
1.10
0.30
4.8
5.0
—
—
—
0
0
174
1667
1.08
0.29
5.8
7.1
2.83
2.81
%
0.05
164
1579
17
139
1.23
0.29
1.0
1.1
1.44
1.54
g/l
1.29
17
139
180
1727
1.08
0.29
5.3
5.6
6.16
6.30
mmol/l
0.59
162
1571
13
103
1.27
0.28
1.0
1.6
—
90.00
—
0
12
9
117
0.76
0.28
1.1
1.3
—
—
—
0
0
15
122
1.24
0.27
1.1
1.1
—
—
—
0
0
35
310
1.14
0.27
4.3
5.1
1.59
1.63
%
0.10
30
285
17
141
1.22
0.26
1.0
1.1
0.89
0.85
g/l
0.55
17
141
5
72
0.69
0.26
1.8
4.2
7.39
7.41
ph
—
5
72
33
371
0.88
0.25
1.6
1.2
—
—
—
0
0
373
3699
1.20
0.25
18.5
18.4
263.45
260.65
e9/l
0.37
368
3623
186
1797
1.07
0.24
5.8
7.1
0.53
0.54
e9/l
0.06
163
1563
72
671
1.09
0.24
1.5
1.3
19.60
21.65
iu/ml
0.15
30
184
20
232
0.85
0.23
1.2
1.2
—
—
—
0
0
10
79
1.27
0.22
1.5
1.3
264.40
329.08
ug/g
—
5
41
45
411
1.11
0.22
1.8
2.1
—
—
—
0
0
5
41
1.22
0.22
1.4
3.7
19.04
16.90
%
—
5
41
74
694
1.08
0.21
1.7
2.2
0.69
0.97
mg/l
1.36
53
495
186
1802
1.06
0.21
5.8
7.1
0.04
0.04
e9/l
0.20
163
1567
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
7.6
—
4.91
—
0
10
0
10
0.00
0.21
0.0
12.7
—
48.25
—
0
10
0
12
0.00
0.21
0.0
1.3
—
28.25
—
0
12
22
192
1.15
0.21
2.7
4.6
3.81
31.61
ug/l
0.61
14
146
5
43
1.16
0.21
3.0
2.9
—
—
—
0
0
111
1059
1.07
0.21
1.3
1.5
2.18
1.94
g/l
0.72
62
651
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
2.9
—
34.71
—
0
7
373
3703
1.18
0.20
18.3
18.3
4.61
4.56
e12/l
1.58
366
3620
0
14
0.00
0.20
0.0
1.6
—
122.86
—
0
14
33
298
1.12
0.20
1.9
2.2
—
—
—
0
0
96
1008
0.94
0.19
2.2
2.7
—
0.20
—
0
10
373
3704
1.17
0.19
18.4
18.4
6.60
6.68
e9/l
0.37
366
3619
67
629
1.08
0.19
1.5
1.3
9.68
7.10
u/ml
0.14
25
238
151
1458
1.06
0.19
5.0
6.9
10.12
10.67
umol/l
0.49
139
1376
120
1151
1.06
0.19
2.0
1.8
98.30
96.47
pmol/l
0.14
63
595
7
58
1.21
0.18
1.3
1.2
—
—
—
0
0
7
62
1.13
0.17
2.1
1.0
—
—
—
0
0
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
17
148
1.16
0.17
12.1
15.5
95.48
94.79
%
0.49
17
148
30
329
0.90
0.17
1.6
1.8
—
—
—
0
0
5
70
0.71
0.17
4.8
2.5
—
—
—
0
0
8
71
1.13
0.16
1.5
2.4
11.23
10.59
mg/l
—
8
66
33
359
0.91
0.16
7.4
7.4
7.36
7.37
ph
0.62
19
230
6
79
0.76
0.15
2.7
6.9
64.72
62.42
%
—
6
79
35
323
1.09
0.15
8.1
9.7
105.29
104.83
mmol/l
0.26
35
323
25
275
0.90
0.15
3.8
3.6
—
—
—
0
0
20
223
0.89
0.15
1.4
1.3
175.39
245.41
miu/ml
0.49
12
117
333
3361
0.94
0.14
11.6
11.9
16.25
20.84
mg/l
2.67
282
2572
98
1018
0.95
0.14
4.2
6.1
—
—
—
0
0
22
243
0.90
0.14
8.1
11.6
1.11
1.19
mmol/l
0.30
22
237
15
170
0.88
0.14
1.2
1.2
0.38
2.78
u/ml
—
9
109
11
128
0.86
0.13
7.5
17.7
15.64
15.98
%
0.17
11
122
48
452
1.07
0.13
4.9
6.3
0.83
0.81
mmol/l
0.69
42
433
125
1214
1.04
0.12
1.9
1.9
1.30
1.31
mmol/l
0.08
106
1081
178
1744
1.04
0.12
3.7
3.5
0.00
0.00
estimate
-0.00
30
331
37
347
1.07
0.12
1.3
1.6
2.87
3.35
mmol/l
2.41
26
242
31
332
0.93
0.11
1.5
1.4
—
—
—
0
0
14
157
0.89
0.11
1.1
1.1
0.62
8.54
u/ml
—
6
112
170
1734
0.97
0.11
3.8
3.4
0.00
4.34
estimate
0.50
31
347
19
208
0.91
0.10
1.1
1.1
—
—
—
0
0
14
125
1.12
0.10
2.5
3.9
18.04
8.56
umol/l
—
8
96
21
193
1.09
0.10
1.4
1.2
—
—
—
0
0
5
44
1.14
0.10
2.4
2.1
—
—
—
0
0
5
48
1.04
0.09
1.8
1.2
—
—
—
0
0
119
1218
0.97
0.09
2.1
2.2
—
—
—
0
0
6
55
1.09
0.09
3.3
4.1
2.15
7.28
u/ml
—
6
55
12
107
1.13
0.08
1.0
1.6
—
—
—
0
0
12
107
1.13
0.08
7.2
4.6
24.04
24.34
mmol/l
0.20
12
102
5
63
0.79
0.08
1.0
1.1
—
—
—
0
0
62
641
0.96
0.08
3.0
3.0
318.75
319.15
umol/l
0.01
53
582
64
661
0.96
0.07
3.5
2.8
8.04
8.32
e6/l
0.05
56
596
6
75
0.80
0.07
1.5
2.0
—
—
—
0
0
90
922
0.97
0.07
3.7
2.5
—
—
—
0
0
34
356
0.95
0.07
7.2
7.3
6.00
5.81
kpa
0.91
34
348
94
961
0.97
0.06
1.8
1.8
—
—
—
0
0
11
99
1.11
0.06
10.1
9.3
—
—
—
0
0
65
632
1.03
0.06
2.7
4.2
—
—
—
0
0
10
110
0.91
0.05
1.2
3.0
1.98
1.22
g/l
—
10
101
60
585
1.03
0.05
1.7
1.7
—
—
—
0
0
98
996
0.98
0.04
2.3
2.8
0.00
0.01
estimate
0.69
26
283
14
150
0.93
0.04
1.1
1.1
0.26
0.96
u/ml
—
8
88
20
190
1.06
0.04
1.7
1.6
—
—
—
0
0
131
1295
1.02
0.04
3.3
3.1
0.00
0.01
estimate
0.69
24
296
31
321
0.96
0.03
6.0
6.9
4.61
4.76
kpa
0.21
31
314
23
220
1.05
0.03
2.0
2.2
0.27
0.16
e6/l
0.46
23
209
38
391
0.97
0.03
2.2
2.5
354.65
4259.13
u/l
2.44
15
138
14
149
0.94
0.03
1.4
1.6
154.60
199.86
u/ml
—
8
75
27
279
0.97
0.02
11.4
12.4
25.04
24.98
mmol/l
0.04
27
279
170
1712
0.99
0.02
3.7
3.4
0.00
0.00
estimate
-0.00
30
351
20
208
0.96
0.02
11.2
14.7
97.53
96.54
%
1.12
20
202
31
318
0.97
0.02
9.4
12.6
—
—
—
0
0
12
113
1.06
0.02
18.0
10.7
23.68
24.56
mmol/l
0.42
12
106
92
911
1.01
0.01
4.5
3.5
0.00
0.00
estimate
0.50
28
333
43
422
1.02
0.01
11.0
8.9
1.19
1.15
mmol/l
0.31
36
396
23
236
0.97
0.00
10.7
13.4
5.02
5.14
kpa
0.45
23
226
23
236
0.97
0.00
10.7
13.4
13.72
14.01
kpa
0.11
23
227
318
3174
1.01
0.00
12.3
13.0
3.92
3.91
mmol/l
0.29
308
3076
21
212
0.99
0.00
1.6
1.4
—
—
—
0
0
14
141
0.99
0.00
5.3
5.0
0.62
0.62
%
0.01
14
141
85
852
1.00
0.00
1.7
1.9
—
—
—
0
0
23
231
1.00
0.00
10.6
13.7
0.51
0.74
mmol/l
0.19
17
197
17
167
1.02
0.00
1.5
1.9
1.24
4.89
iu/ml
—
5
34
318
3175
1.01
0.00
12.5
12.9
139.72
139.65
mmol/l
0.20
311
3091
84
845
0.99
0.00
3.9
3.2
1.02
1.02
kg/l
0.09
56
535
10
96
1.04
0.00
1.1
1.1
—
—
—
0
0
10
96
1.04
0.00
1.1
1.1
—
—
—
0
0
19
194
0.98
0.00
11.8
14.5
117.84
121.37
g/l
0.29
19
189
23
234
0.98
0.00
10.7
13.6
7.40
7.42
ph
0.50
13
120
50
495
1.01
0.00
3.2
3.2
442.67
742.94
ng/l
0.27
24
293
342
3416
1.01
0.00
13.4
13.6
69.85
69.52
umol/l
0.08
337
3366
38
376
1.01
0.00
2.3
4.6
4.38
6.76
umol/l
1.64
32
327
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.02
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
60.33
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
10.7
—
26.18
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
907.20
—
0
5
0
9
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
28.4
—
0.46
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
101.00
—
0
5
8
87
0.92
-0.00
5.0
3.1
55.75
56.01
%
—
8
87
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
30.20
—
0
5
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.7
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
79.43
—
0
7
6
59
1.02
-0.00
3.0
4.6
4.83
7.72
pmol/l
—
6
59
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
13.70
—
0
7
0
9
0.00
-0.00
0.0
2.4
—
151.44
—
0
9

Mortality – FinRegistry

Association

Association between endpoint K11_MESIAL_BITE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MESIAL_BITE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MESIAL_BITE – Mesial bite

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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