Mesial bite

K11_MESIAL_BITE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.21
  • Hospital discharge: ICD-10 K07.21
  • Cause of death: ICD-10 K07.21

3 out of 7 registries used, show all original rules.

365

4. Check minimum number of events

None

365

5. Include endpoints

None

365

6. Filter based on genotype QC (FinnGen only)

365

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8284 4430 3837
Only index persons 7332 3977 3355
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.11
Only index persons 0.14 0.15 0.13
Median age at first event (years)
Whole population 11.24 11.42 10.94
Only index persons 12.14 12.32 11.94

-FinnGen-

Key figures

All Female Male
Number of individuals 365 259 106
Unadjusted period prevalence (%) 0.08 0.09 0.05
Median age at first event (years) 26.32 27.43 23.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
323
Matched controls
3228
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
+∞
323.0
323
*
K07.24
ICD-10 Finland
Open bite
33.7
80.1
106
46
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
15.2
52.4
91
81
SBB10
NOMESCO Finland
Teeth copy
6.6
48.4
158
409
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
7.6
38.5
100
179
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
60.0
36.4
42
8
K07.14
ICD-10 Finland
Retrognaty, maxillary
45.3
33.0
40
10
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.4
30.6
89
181
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
10.1
27.7
57
67
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
5.3
26.1
90
221
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
4.5
25.9
109
329
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
5.9
24.8
75
157
EEC05
NOMESCO Finland
Le Fort I osteotomy
73.3
24.2
27
*
K07.60
ICD-10 Finland
Snapping jaw
7.9
23.6
56
83
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
6.4
23.6
66
124
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
70.4
23.2
26
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
4.9
23.1
84
216
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
4.8
22.6
83
215
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
4.6
21.7
84
229
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
5.3
21.6
71
162
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
21.2
205
1152
SAA03
NOMESCO Finland
Extended examination of mouth
3.2
20.8
225
1358
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
4.7
20.8
77
200
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
4.3
18.3
74
208
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
16.9
170
925
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.3
15.5
42
75
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.8
15.4
72
228
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
3.8
15.3
72
229
K07.13
ICD-10 Finland
Retrognaty, mandibular
6.8
15.3
39
64
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
7.7
15.1
35
50
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
5.0
14.5
48
109
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.0
14.2
61
179
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
3.8
14.1
65
203
SXC05
NOMESCO Finland
Other oral or dental procedure
3.3
14.0
79
287
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.3
13.8
79
290
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.1
13.5
55
153
SJC00
NOMESCO Finland
Bracket with fixed attachment
42.0
13.3
16
*
SAA01
NOMESCO Finland
Simple examination of mouth
2.9
12.9
272
2094
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
3.7
12.6
59
186
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
3.6
12.0
57
181
SAA02
NOMESCO Finland
Basic examination of mouth
2.9
11.1
280
2246
OIKK
NOMESCO Finland
NA
3.1
11.0
65
243
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.2
10.8
59
208
K07.10
ICD-10 Finland
Asymmetry of jaw
17.4
10.0
15
9
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.1
9.9
183
1228
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
3.1
9.9
56
203
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
8.3
9.0
19
24
F45.8
ICD-10 Finland
Other somatoform disorders
3.5
8.9
42
133
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
51.4
8.7
10
*
WZA90
NOMESCO Finland
Other doctors statement
2.1
8.4
116
675
SJB60
NOMESCO Finland
External device grinding and adaptation
3.2
8.3
43
146
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
4.7
8.3
27
61
K03.66
ICD-10 Finland
Tooth plaque
2.8
7.8
52
209
D82
ICPC
Teeth/gum disease
2.0
7.7
146
956
SFA00
NOMESCO Finland
Small filling
2.7
7.2
52
218
OIKH
NOMESCO Finland
NA
2.9
7.0
44
169
K00.00
ICD-10 Finland
Hypodontia
4.6
6.8
22
50
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
7.4
6.8
15
21
EBA00
NOMESCO Finland
Extraction of tooth
1.9
6.6
136
900
K03.64
ICD-10 Finland
Dental calculus supragingival
1.9
6.6
132
866
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
3.2
6.6
33
110
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.0
6.5
92
534
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
6.4
107
655
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
14.7
6.4
10
7
K03.00
ICD-10 Finland
Approximal wear
3.6
6.4
27
79
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
8.4
6.4
13
16
SDA02
NOMESCO Finland
Parodonthologic therapy
1.9
6.4
130
857
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
27.3
6.3
8
*
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.2
6.3
63
314
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
6.2
87
500
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
6.2
203
1560

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
201
2.29
5.52
3.5
3.9
—
—
—
0
0
20
69
3.01
4.68
1.5
1.3
—
—
—
0
0
85
554
1.70
4.13
3.3
2.9
—
—
—
0
0
51
318
1.70
2.89
1.4
1.6
1053.82
1168.60
nmol/l
0.38
30
241
9
28
3.27
2.32
1.1
1.1
—
—
—
0
0
106
822
1.41
2.23
2.4
2.3
—
—
—
0
0
85
1101
0.70
2.14
3.4
2.9
—
—
—
0
0
30
176
1.77
2.13
3.4
4.2
0.17
0.39
%
—
6
38
29
171
1.76
2.04
1.9
1.8
7.26
8.21
u/l
0.24
21
140
9
34
2.69
1.87
1.3
1.6
—
—
—
0
0
28
169
1.71
1.83
3.8
4.8
0.17
0.00
%
—
6
42
29
178
1.68
1.79
3.6
4.8
0.00
0.14
%
—
6
51
32
204
1.62
1.72
1.7
1.7
23.32
14.67
iu/l
0.83
25
168
6
19
3.19
1.67
1.3
1.4
—
—
—
0
0
30
192
1.61
1.60
3.7
4.6
0.43
0.73
%
—
7
60
6
20
3.03
1.58
1.2
1.1
—
—
—
0
0
6
20
3.03
1.58
1.0
1.3
—
—
—
0
0
115
1370
0.77
1.58
3.8
3.1
0.00
0.00
estimate
0.00
25
260
45
618
0.69
1.54
5.3
3.1
—
—
—
0
0
5
15
3.36
1.53
2.6
3.4
—
—
—
0
0
289
2701
1.34
1.45
5.0
4.4
1.94
2.26
mu/l
0.33
260
2521
9
40
2.28
1.41
2.4
1.4
12.99
13.11
%
—
9
40
51
670
0.72
1.35
2.8
3.5
7.39
7.40
ph
0.45
11
110
143
1635
0.79
1.35
2.8
2.8
—
—
—
0
0
116
976
1.28
1.34
4.6
6.2
—
—
—
0
0
0
40
0.00
1.33
0.0
1.2
—
—
—
0
0
40
286
1.45
1.32
1.2
1.2
—
—
—
0
0
326
3118
1.43
1.29
9.0
9.0
—
—
—
0
0
251
2321
1.26
1.25
4.5
3.8
14.44
14.37
pmol/l
0.20
224
2112
79
960
0.77
1.22
3.1
3.5
26.61
79.05
e6/l
2.09
57
638
119
1373
0.80
1.18
4.4
4.3
0.00
0.00
estimate
0.00
24
268
265
2474
1.26
1.17
3.9
3.3
5.67
5.61
mmol/l
0.32
238
2280
16
257
0.61
1.16
1.9
2.1
27.45
30.77
u/l
0.33
11
210
5
20
2.52
1.15
2.6
1.8
—
—
—
0
0
28
194
1.48
1.10
1.6
1.9
3.01
4.05
e9/l
2.81
17
171
188
1706
1.21
1.04
6.9
8.8
3.83
3.83
e9/l
0.01
162
1486
112
969
1.22
0.99
1.4
1.4
1.67
1.67
u/ml
0.00
19
228
49
384
1.32
0.98
1.3
1.6
438.78
20060309.46
pmol/l
0.50
36
334
7
36
1.96
0.97
1.7
1.6
—
—
—
0
0
0
31
0.00
0.97
0.0
2.3
—
762.25
—
0
12
0
31
0.00
0.97
0.0
1.3
—
295.00
—
0
6
123
1391
0.83
0.96
3.7
3.1
0.00
0.00
estimate
0.00
24
263
171
1548
1.20
0.94
5.1
6.6
0.18
0.18
e9/l
0.09
147
1387
5
102
0.48
0.91
1.0
1.1
—
5.17
—
0
22
24
332
0.70
0.89
1.3
1.8
—
—
—
0
0
26
354
0.71
0.88
1.2
1.3
—
—
—
0
0
6
30
2.02
0.87
2.7
6.1
—
—
—
0
0
41
319
1.32
0.87
1.5
1.5
—
—
—
0
0
131
1170
1.19
0.82
2.6
2.5
69.92
71.51
nmol/l
0.26
114
1079
5
98
0.50
0.79
1.2
1.2
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
12
75
1.62
0.76
1.0
1.6
—
57.78
—
0
9
170
1562
1.17
0.74
5.0
6.1
2.02
2.05
e9/l
0.15
149
1402
6
109
0.54
0.73
3.3
2.4
—
—
—
0
0
40
495
0.78
0.72
2.7
2.7
593.76
579.93
mosm/kgh2o
0.12
29
426
162
1485
1.16
0.72
5.1
6.2
31.69
30.92
%
0.41
151
1404
16
109
1.49
0.72
2.2
1.6
—
—
—
0
0
160
1467
1.16
0.71
4.5
6.0
54.37
54.93
%
0.25
150
1389
70
598
1.21
0.71
1.9
2.1
154.17
284.60
u/l
0.60
60
564
5
26
1.94
0.71
2.2
1.9
93.68
91.61
%
—
5
26
13
192
0.67
0.70
2.7
2.5
0.62
0.71
ug/l
—
6
104
62
726
0.82
0.68
4.6
6.8
—
—
—
0
0
149
1364
1.16
0.67
5.0
6.4
0.68
0.64
%
0.46
136
1279
5
28
1.80
0.66
3.0
1.5
581.60
304.09
pmol/l
—
5
23
26
333
0.76
0.62
1.6
1.8
—
—
—
0
0
71
813
0.84
0.62
2.5
2.6
—
—
—
0
0
14
198
0.70
0.62
1.4
1.3
—
—
—
0
0
17
122
1.41
0.61
2.5
2.3
88.75
92.43
ng/l
0.02
12
115
0
20
0.00
0.60
0.0
2.0
—
37.65
—
0
20
26
331
0.77
0.60
1.6
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
3.3
—
190.91
—
0
11
153
1417
1.14
0.57
5.0
6.3
2.83
2.75
%
0.19
142
1330
58
670
0.84
0.56
4.5
3.1
1.01
1.02
kg/l
—
9
85
38
314
1.23
0.54
4.6
4.0
1.59
1.74
ug/l
0.13
30
278
81
720
1.16
0.54
4.7
4.7
—
—
—
0
0
206
1950
1.13
0.53
5.9
6.5
80.65
81.21
u/l
0.06
190
1818
56
645
0.84
0.53
1.8
1.7
1.31
1.32
mmol/l
0.04
45
572
79
702
1.16
0.53
1.5
1.7
—
—
—
0
0
27
335
0.79
0.52
1.9
1.8
—
—
—
0
0
11
157
0.69
0.52
1.5
1.5
—
—
—
0
0
25
312
0.79
0.51
1.6
1.8
—
—
—
0
0
153
1425
1.13
0.51
5.4
6.5
7.82
8.16
%
0.74
141
1344
34
409
0.81
0.51
2.4
2.8
6.35
4.16
e6/l
0.43
20
211
80
716
1.15
0.49
2.4
2.6
15.41
17.05
ng/l
0.16
41
333
227
2168
1.12
0.49
5.0
4.1
37.56
37.75
mmol/mol
0.12
207
2044
11
154
0.71
0.48
1.5
1.4
—
—
—
0
0
246
2362
1.13
0.48
3.5
3.1
1.16
1.19
mmol/l
0.34
220
2218
7
47
1.50
0.48
1.3
4.1
3.96
3.76
mmol/l
—
7
42
70
783
0.87
0.46
2.8
3.1
24.90
41.15
e6/l
0.42
52
595
11
153
0.71
0.46
1.5
1.4
—
—
—
0
0
11
77
1.44
0.46
1.0
1.6
—
—
—
0
0
7
50
1.41
0.45
1.0
1.0
—
—
—
0
0
93
847
1.13
0.44
1.7
1.7
102.68
96.76
pmol/l
0.44
47
435
7
51
1.38
0.44
1.4
2.4
—
—
—
0
0
57
644
0.86
0.43
2.5
4.3
93.54
93.54
%
0.00
57
635
125
1342
0.90
0.43
5.8
8.1
0.00
0.00
e9/l
0.00
103
1078
138
1289
1.11
0.43
4.8
4.1
—
—
—
0
0
65
579
1.15
0.43
1.5
2.1
0.76
0.94
mg/l
0.58
46
407
6
91
0.65
0.43
1.0
1.8
—
—
—
0
0
5
32
1.57
0.42
3.4
2.2
1.12
1.76
mmol/l
—
5
32
31
259
1.22
0.42
1.2
1.3
—
—
—
0
0
26
213
1.24
0.42
1.8
1.6
244.65
316.32
mu/l
1.60
26
196
101
928
1.12
0.42
2.7
4.9
37.62
37.37
g/l
0.21
88
869
25
303
0.81
0.41
1.8
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
6.42
—
0
16
108
999
1.12
0.40
2.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
13.9
—
12.39
—
0
18
92
1000
0.89
0.39
1.7
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
40
346
1.18
0.39
1.2
1.2
—
—
—
0
0
65
720
0.88
0.38
5.1
3.3
0.00
0.00
estimate
0.00
23
262
56
499
1.14
0.37
4.3
4.1
12.86
12.03
mg/mmol
0.02
34
324
158
1497
1.10
0.36
5.0
6.2
0.52
0.53
e9/l
0.52
137
1316
34
292
1.18
0.36
1.2
1.3
23.86
154.72
iu/ml
—
7
116
19
153
1.26
0.36
3.3
5.5
—
—
—
0
0
6
42
1.44
0.35
1.7
1.7
—
—
—
0
0
13
167
0.77
0.35
2.0
2.1
—
—
—
0
0
6
45
1.34
0.34
1.3
1.1
—
—
—
0
0
38
332
1.16
0.33
1.6
1.9
—
—
—
0
0
53
475
1.14
0.33
3.1
3.4
68.83
80.80
mg/l
0.08
28
311
22
263
0.83
0.33
5.0
7.4
6.03
5.83
kpa
0.64
22
257
158
1503
1.09
0.33
5.0
6.2
0.04
0.04
e9/l
0.02
137
1324
294
3001
0.90
0.33
9.4
10.1
16.55
20.89
mg/l
1.85
234
2178
15
187
0.79
0.33
1.1
1.2
—
—
—
0
0
299
3049
0.89
0.33
8.5
8.4
25.60
24.82
u/l
0.32
290
2939
14
176
0.79
0.32
1.1
1.1
—
—
—
0
0
6
47
1.28
0.32
2.8
2.9
—
—
—
0
0
35
399
0.86
0.31
2.7
3.1
777.87
640.39
ng/l
0.07
16
235
7
57
1.23
0.29
5.6
3.5
54.71
54.11
%
—
7
57
26
301
0.85
0.29
2.6
1.7
—
—
—
0
0
8
62
1.30
0.28
6.5
4.4
—
—
—
0
0
21
177
1.20
0.28
16.3
17.2
1.05
1.29
inr
—
6
33
9
117
0.76
0.28
2.7
2.2
0.34
0.15
e6/l
—
9
111
8
64
1.26
0.27
7.0
7.1
—
—
—
0
0
54
492
1.11
0.27
1.3
1.4
20.28
20.86
nmol/l
0.12
42
424
158
1518
1.07
0.25
3.0
2.8
67.34
73.91
ug/l
0.30
149
1420
108
1025
1.08
0.23
5.2
7.1
1.23
1.22
mmol/l
0.99
95
946
68
729
0.92
0.23
2.6
3.0
—
—
—
0
0
37
333
1.12
0.23
1.8
2.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
7
95
0.73
0.22
7.0
16.6
—
—
—
0
0
189
1948
0.94
0.22
4.4
3.9
—
—
—
0
0
67
717
0.92
0.22
2.7
3.1
0.09
0.32
e6/l
2.96
49
529
78
733
1.08
0.22
2.8
3.1
8.54
8.58
mmol/l
0.02
65
646
23
262
0.87
0.22
1.2
1.4
—
—
—
0
0
28
314
0.88
0.21
1.7
4.0
3.88
7.18
umol/l
2.06
23
264
92
871
1.08
0.21
1.2
1.4
2.27
1.94
g/l
0.88
50
526
0
11
0.00
0.21
0.0
1.7
—
111.18
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
46
500
0.91
0.21
2.5
4.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
269.71
—
0
7
81
764
1.08
0.21
4.8
5.5
1.18
1.11
inr
0.35
24
241
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.7
—
32.71
—
0
7
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1417.21
—
0
14
16
186
0.85
0.19
2.3
8.1
24.04
23.86
mmol/l
0.11
16
180
78
737
1.07
0.19
2.6
2.5
52.72
55.88
u/l
0.58
65
673
56
522
1.09
0.19
2.5
2.3
123.88
105.25
ug/g
0.18
40
391
28
310
0.90
0.18
1.4
1.5
—
—
—
0
0
23
258
0.88
0.18
1.6
1.8
—
—
—
0
0
109
1045
1.06
0.18
1.9
2.0
—
—
—
0
0
18
205
0.87
0.17
5.6
9.8
25.29
25.13
mmol/l
0.09
18
205
10
82
1.23
0.17
1.0
2.9
1.97
1.24
g/l
—
10
73
27
244
1.12
0.17
2.0
2.3
—
—
—
0
0
14
162
0.86
0.16
6.9
12.5
97.41
96.51
%
0.75
14
156
16
182
0.87
0.15
7.8
9.2
1.08
1.23
mmol/l
0.70
16
172
21
234
0.89
0.15
3.9
7.0
4.52
4.70
kpa
0.20
21
229
23
254
0.90
0.15
4.0
3.3
—
—
—
0
0
100
963
1.05
0.14
2.4
2.2
—
—
—
0
0
26
237
1.10
0.14
2.3
3.3
0.23
0.23
g/l
0.00
21
224
117
1132
1.05
0.14
5.5
7.5
1.23
1.22
mmol/l
0.46
97
991
8
96
0.83
0.14
2.8
2.0
—
—
—
0
0
55
521
1.07
0.13
1.5
1.3
19.30
23.01
iu/ml
0.25
22
159
9
109
0.82
0.13
1.0
1.1
—
—
—
0
0
51
537
0.94
0.12
2.8
2.8
309.50
4546.14
umol/l
1.84
40
477
24
261
0.91
0.12
1.4
1.4
—
—
—
0
0
54
514
1.06
0.11
1.4
1.2
13.01
7.33
u/ml
0.23
18
197
51
536
0.94
0.11
2.6
2.6
9.28
8.42
e6/l
0.12
42
472
51
485
1.06
0.11
1.7
1.6
—
—
—
0
0
32
342
0.93
0.11
3.1
6.1
0.84
0.81
mmol/l
1.47
27
326
15
166
0.90
0.10
3.1
2.0
—
—
—
0
0
71
685
1.05
0.10
2.0
2.1
2.87
2.78
mg/l
0.11
62
580
5
46
1.09
0.09
1.8
3.2
2.25
5.77
u/ml
—
5
41
16
176
0.90
0.09
1.6
1.4
—
—
—
0
0
5
47
1.06
0.09
1.0
1.3
—
—
—
0
0
6
57
1.05
0.08
1.7
2.2
10.42
10.24
mg/l
—
6
52
5
61
0.82
0.08
3.8
1.6
—
—
—
0
0
25
234
1.07
0.08
1.2
1.3
—
—
—
0
0
7
67
1.05
0.08
4.4
3.5
—
—
—
0
0
249
2467
1.03
0.07
4.1
3.4
1.42
1.48
mmol/l
1.68
222
2319
119
1213
0.97
0.07
4.6
6.4
10.23
10.37
umol/l
0.10
109
1136
279
2811
0.97
0.07
9.4
10.7
3.89
3.90
mmol/l
0.13
268
2708
8
90
0.89
0.07
1.3
2.0
—
—
—
0
0
17
183
0.93
0.06
6.3
11.5
13.39
14.08
kpa
0.26
17
175
17
183
0.93
0.06
6.3
11.5
4.98
5.13
kpa
0.47
17
174
339
3404
0.94
0.06
14.5
15.1
136.91
135.47
g/l
1.26
334
3352
279
2809
0.97
0.06
9.4
10.7
139.79
139.65
mmol/l
0.51
272
2714
63
614
1.03
0.05
1.4
1.5
—
—
—
0
0
10
110
0.91
0.05
1.6
1.6
—
—
—
0
0
339
3402
0.95
0.05
14.5
15.0
6.54
6.68
e9/l
0.69
329
3299
17
181
0.94
0.05
6.3
11.7
0.81
0.85
mmol/l
0.04
12
147
251
2493
1.02
0.04
4.0
3.5
4.69
4.65
mmol/l
0.31
226
2353
25
239
1.05
0.04
4.6
5.0
1.67
1.58
%
0.18
20
218
17
160
1.07
0.04
2.4
4.5
4.29
36.13
ug/l
—
9
124
12
111
1.08
0.04
6.7
11.6
95.63
94.54
%
0.78
12
111
80
787
1.02
0.03
2.5
3.1
2.39
2.37
mmol/l
0.95
65
697
339
3400
0.96
0.03
14.5
15.0
4.63
4.55
e12/l
2.05
329
3299
32
330
0.97
0.03
2.2
2.4
325.29
3495.95
u/l
2.19
14
116
339
3399
0.96
0.02
14.4
14.9
29.74
29.87
pg
0.60
334
3348
294
2930
1.02
0.02
9.2
11.3
40.54
40.23
%
0.34
220
2420
147
1461
1.01
0.01
3.9
4.9
6.26
6.29
mmol/l
0.05
128
1300
192
1929
0.99
0.01
3.1
3.1
65.63
34.60
u/l
0.87
183
1840
339
3397
0.97
0.01
14.5
15.0
89.10
89.29
fl
0.32
334
3346
32
327
0.98
0.01
6.7
8.2
1.13
1.13
mmol/l
0.01
25
309
17
176
0.96
0.00
6.9
3.3
—
—
—
0
0
19
184
1.03
0.00
1.8
1.6
—
—
—
0
0
12
118
1.02
0.00
1.2
1.5
131.80
226.37
u/ml
—
6
60
78
782
1.00
0.00
3.4
2.4
—
—
—
0
0
17
169
1.01
0.00
1.4
1.2
—
—
—
0
0
251
2508
1.00
0.00
4.2
3.7
2.88
2.79
mmol/l
0.96
224
2351
10
97
1.03
0.00
1.1
1.1
—
—
—
0
0
11
113
0.97
0.00
1.9
3.1
4.85
7.17
umol/l
—
6
88
12
117
1.03
0.00
9.8
11.5
1.08
1.20
mg/l
0.56
12
109
23
233
0.99
0.00
6.7
10.8
—
—
—
0
0
10
95
1.05
0.00
3.6
11.7
23.86
24.25
mmol/l
—
10
88
204
2037
1.00
0.00
4.6
3.7
7.68
8.59
mm/h
0.67
189
1884
81
815
0.99
0.00
1.7
1.7
—
—
—
0
0
19
186
1.02
0.00
1.5
1.3
—
—
—
0
0
339
3394
0.98
0.00
14.6
15.1
262.61
260.39
e9/l
0.26
331
3295
18
176
1.02
0.00
1.3
1.4
175.39
259.43
miu/ml
0.61
12
91
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
16.10
—
0
8
0
6
0.00
0.00
0.0
1.2
—
4.32
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
8
87
0.92
0.00
1.1
1.1
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
26.5
—
0.45
—
0
6
0
6
0.00
0.00
0.0
10.7
—
26.18
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
10.1
—
49.17
—
0
9
6
60
1.00
0.00
1.8
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
82.40
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
9.9
—
—
—
0
0
5
55
0.91
0.00
1.6
2.0
—
—
—
0
0
5
52
0.96
0.00
2.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
137.14
—
0
7
0
7
0.00
0.00
0.0
5.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
9
91
0.99
0.00
1.1
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
2.8
9.9
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_MESIAL_BITE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MESIAL_BITE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MESIAL_BITE – Mesial bite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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