No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
168 |
4. Check minimum number of eventsNone |
168 |
5. Include endpointsNone |
168 |
6. Filter based on genotype QC (FinnGen only) |
139 |
Control definitions (FinnGen only)
- Control exclude
- AB1_OTHER_BACTERIAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Actinomycosis
based on the number of shared cases.
Similar with more cases:
- Actinomycosis, including avohilmo
- Other bacterial diseases
- Other bacterial diseases, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1062 | 550 | 497 |
| Only index persons | 861 | 471 | 390 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 55.29 | 54.14 | 56.58 |
| Only index persons | 53.82 | 51.92 | 56.12 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 139 | 66 | 73 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 56.73 | 52.76 | 60.31 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 147
- Matched controls
- 1470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A42.8
ICD-10 Finland
Other forms of actinomycosis
+∞
37.1
34
*
A42.0
ICD-10 Finland
Pulmonary actinomycosis
+∞
31.4
29
*
A42.9
ICD-10 Finland
Actinomycosis, unspecified
+∞
29.1
27
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
44.9
26.5
32
9
A42.2
ICD-10 Finland
Cervicofacial actinomycosis
+∞
18.1
17
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.8
16.1
28
49
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
14.8
14
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
+∞
13.8
13
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.2
13.7
32
74
A42.7
ICD-10 Finland
Actinomycotic sepsis
+∞
11.6
11
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
10.5
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.0
9.2
21
47
TGC00
NOMESCO Finland
Bronchial lavation
15.3
8.9
14
10
A46
ICD-10 Finland
Erysipelas
5.3
8.9
19
40
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
8.8
52
225
K05.31
ICD-10 Finland
Periodontitis pronounced
4.1
8.6
26
73
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
7.4
77
439
11399
ICD-8 Finland
Actinomycosis
+∞
7.3
7
*
JN4BD
NOMESCO Finland
Extensive body CT
4.1
7.2
21
57
R50.9
ICD-10 Finland
Fever, unspecified
3.4
7.2
29
99
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
7.0
35
136
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.5
6.7
68
379
M04AA01
ATC
allopurinol; systemic
3.4
6.7
27
92
TLC02
NOMESCO Finland
Simple extraction of IUD
8.8
6.5
13
16
EBA15
NOMESCO Finland
Extraction of multiple teeth
9.9
6.4
12
13
A06AD11
ATC
lactulose; oral
3.2
6.4
29
106
GD2SN
NOMESCO Finland
Lung ventilation SPECT
+∞
6.3
6
*
GD1UN
NOMESCO Finland
Lung circulation SPECT
+∞
6.3
6
*
A42.1
ICD-10 Finland
Abdominal actinomycosis
+∞
6.3
6
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
6.3
24
79
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
6.3
6.0
15
26
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
29
30
11.80
25.87
2.9
2.3
—
—
—
0
0
45
156
3.72
11.21
2.6
1.7
—
—
—
0
0
27
67
4.71
10.50
2.1
1.3
—
—
—
0
0
37
120
3.78
10.08
1.5
1.6
—
—
—
0
0
22
48
5.21
9.91
7.8
1.8
2.28
1.39
mmol/l
0.43
17
38
17
17
11.14
9.31
2.0
1.1
—
—
—
0
0
16
16
11.06
8.78
1.8
1.3
—
—
—
0
0
19
27
7.91
8.58
1.8
1.2
—
—
—
0
0
85
493
2.72
8.10
8.2
3.8
33.73
36.06
g/l
2.17
79
463
18
30
6.68
7.35
1.8
1.2
—
—
—
0
0
12
10
12.93
7.22
1.3
1.1
—
—
—
0
0
11
10
11.77
6.41
2.0
1.5
—
—
—
0
0
31
120
3.01
6.21
1.6
1.6
—
—
—
0
0
10
8
13.29
6.18
1.5
1.0
—
—
—
0
0
14
22
6.91
6.02
7.1
2.0
25.60
25.15
mmol/l
0.09
14
22
14
22
6.91
6.02
1.4
1.2
—
—
—
0
0
97
655
2.41
5.97
16.9
8.5
4.21
3.89
e9/l
0.77
86
572
10
9
11.81
5.89
2.2
1.3
—
—
—
0
0
10
9
11.81
5.89
2.2
1.3
—
—
—
0
0
10
9
11.81
5.89
2.2
1.3
—
—
—
0
0
14
23
6.61
5.85
1.4
1.2
—
—
—
0
0
39
177
2.64
5.79
6.1
2.5
0.81
0.82
mmol/l
0.20
39
165
11
13
9.04
5.67
1.3
1.1
—
—
—
0
0
10
10
10.62
5.62
2.0
1.5
—
—
—
0
0
13
21
6.68
5.52
1.5
1.5
—
—
—
0
0
16
36
4.86
5.24
1.3
3.7
1.07
3.19
ratio
—
10
16
15
34
4.79
4.91
1.3
1.1
—
—
—
0
0
11
17
6.90
4.87
1.5
1.3
—
—
—
0
0
9
10
9.49
4.85
1.1
1.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
26
5.38
4.76
1.7
1.7
0.25
0.29
iu/ml
—
8
12
115
882
2.40
4.66
16.9
6.8
88.51
77.90
u/l
0.78
109
824
83
561
2.10
4.64
14.2
6.3
1.22
1.21
mmol/l
0.23
73
485
68
438
2.03
4.22
5.7
3.7
30.85
48.83
ng/l
0.86
52
314
7
7
10.42
4.05
2.7
1.1
2.06
1.76
mmol/l
—
7
7
48
279
2.07
3.89
3.8
2.1
—
—
—
0
0
57
353
2.00
3.88
4.9
3.3
909.35
1064.64
ng/l
0.32
49
295
14
45
3.33
3.76
1.6
2.1
41.86
43.84
u/l
0.12
14
37
9
16
5.91
3.72
1.4
1.2
—
—
—
0
0
22
95
2.55
3.54
3.4
1.9
440.95
389.75
nmol/l
0.33
22
87
6
6
10.35
3.53
1.0
1.0
—
—
—
0
0
8
14
5.97
3.39
1.6
1.2
—
—
—
0
0
12
34
3.75
3.28
4.2
1.7
—
—
—
0
0
57
372
1.87
3.22
3.8
3.2
36.33
30.14
u/l
0.69
57
352
29
149
2.18
3.18
10.7
7.9
103.79
103.78
mmol/l
0.01
29
149
6
8
7.76
3.08
1.0
1.0
—
—
—
0
0
20
89
2.44
3.03
1.8
2.4
6.51
7.17
ug/l
0.05
14
78
5
5
10.28
3.00
1.4
1.0
—
—
—
0
0
28
147
2.12
2.90
1.5
1.4
—
—
—
0
0
11
33
3.52
2.88
3.1
1.6
—
—
—
0
0
11
33
3.52
2.88
1.0
1.1
—
—
—
0
0
8
18
4.64
2.84
2.8
1.4
—
—
—
0
0
5
6
8.57
2.77
1.0
1.0
—
—
—
0
0
5
6
8.57
2.77
1.8
1.0
—
—
—
0
0
20
93
2.33
2.76
7.1
9.2
1.14
1.33
mmol/l
0.42
20
93
107
870
1.84
2.75
7.4
4.0
19.39
10.76
mm/h
4.17
100
803
8
20
4.17
2.61
1.3
1.2
—
—
—
0
0
10
31
3.38
2.57
1.5
1.3
—
—
—
0
0
6
11
5.63
2.57
1.2
1.2
—
—
—
0
0
39
243
1.82
2.47
1.8
1.7
1.62
1.24
mg/l
0.31
33
195
44
286
1.77
2.42
3.6
2.6
325.61
341.01
umol/l
0.50
36
248
8
22
3.78
2.40
1.8
1.2
—
—
—
0
0
8
22
3.78
2.40
1.5
2.5
—
—
—
0
0
7
17
4.27
2.39
2.3
1.1
—
—
—
0
0
72
538
1.66
2.38
4.1
2.5
—
—
estimate
—
0
0
56
394
1.68
2.31
5.5
2.9
—
—
—
0
0
71
532
1.65
2.30
3.9
2.8
235.18
101.16
ug/l
2.05
61
497
6
13
4.76
2.29
1.0
1.5
—
—
—
0
0
6
13
4.76
2.29
1.0
1.5
—
—
—
0
0
13
54
2.54
2.27
1.4
1.2
—
—
—
0
0
10
37
2.82
2.11
2.5
1.4
0.24
0.24
g/l
—
10
37
10
37
2.82
2.11
1.5
1.4
1.24
1.21
g/l
—
10
37
32
199
1.78
2.02
2.6
2.7
1.51
1.05
e6/l
0.25
18
99
54
392
1.60
1.91
4.9
2.8
2.33
2.37
mmol/l
0.70
47
361
14
66
2.24
1.89
10.7
9.1
27.16
24.80
mmol/l
1.07
14
66
12
53
2.38
1.86
2.3
1.5
—
—
—
0
0
18
96
2.00
1.80
6.7
2.7
3.57
1.97
mmol/l
0.87
18
84
6
18
3.43
1.76
1.5
1.5
—
—
—
0
0
47
337
1.58
1.73
1.8
1.6
23.11
20.74
nmol/l
0.59
38
283
45
320
1.59
1.72
4.0
2.8
0.16
0.37
e6/l
1.37
35
217
65
505
1.51
1.66
2.3
2.0
93.38
98.26
pmol/l
0.46
36
264
5
14
3.66
1.63
3.2
3.9
—
—
—
0
0
5
14
3.66
1.63
3.0
2.3
14.74
16.16
%
—
5
14
14
71
2.07
1.60
10.9
12.0
0.64
0.65
%
0.06
14
71
5
15
3.41
1.53
1.0
1.3
—
—
—
0
0
14
73
2.01
1.49
11.0
11.5
1.49
1.30
%
0.38
14
73
5
16
3.20
1.45
1.0
1.3
—
—
—
0
0
5
16
3.20
1.45
1.0
1.3
—
—
—
0
0
5
16
3.20
1.45
1.0
1.3
—
—
—
0
0
44
324
1.51
1.42
5.9
3.9
0.00
0.01
estimate
0.50
14
115
6
23
2.67
1.38
7.3
2.0
9.75
8.21
pmol/l
—
6
23
5
17
3.01
1.37
1.0
1.3
—
—
—
0
0
83
696
1.44
1.37
7.3
4.5
6.71
6.50
mmol/l
0.44
83
655
74
610
1.43
1.32
5.0
3.7
0.00
0.00
estimate
-0.00
16
128
84
710
1.43
1.30
3.3
2.9
—
—
—
0
0
5
18
2.84
1.29
1.0
1.3
—
—
—
0
0
33
236
1.51
1.21
4.4
2.5
2.47
2.45
mmol/l
0.26
26
216
6
26
2.36
1.20
2.2
1.7
88.83
248.01
ug/l
—
6
26
6
26
2.36
1.20
3.0
1.4
83.50
98.44
pmol/l
—
6
26
6
26
2.36
1.20
1.2
1.1
—
—
—
0
0
74
618
1.40
1.19
5.1
3.7
0.00
12.40
estimate
0.50
16
131
124
1138
1.57
1.18
38.6
12.5
29.61
22.97
mg/l
1.31
109
899
12
65
1.92
1.17
9.3
12.1
26.47
24.68
mmol/l
0.76
12
65
31
222
1.50
1.13
1.5
1.3
62.07
26.33
iu/ml
—
7
71
5
21
2.43
1.10
1.8
1.8
—
—
—
0
0
101
898
1.40
1.07
4.8
4.0
15.12
14.70
pmol/l
0.90
92
813
73
623
1.34
0.97
5.2
3.7
0.00
0.00
estimate
-0.00
13
124
6
28
2.19
0.92
1.7
1.2
618.17
468.50
mg/l
—
6
28
6
28
2.19
0.92
1.2
1.2
—
—
—
0
0
28
205
1.45
0.92
1.4
1.3
32.78
7.35
u/ml
—
10
88
25
179
1.48
0.92
2.8
2.8
2.00
2.42
e6/l
0.11
11
81
15
95
1.64
0.91
2.4
2.0
5.17
0.24
e6/l
0.46
15
90
10
56
1.84
0.90
7.8
2.8
25.04
24.81
mmol/l
—
10
56
13
82
1.64
0.81
5.2
2.2
54.17
69.13
ml/min/173m2
—
6
32
9
55
1.68
0.75
2.6
2.0
—
—
—
0
0
16
109
1.53
0.74
3.8
5.1
4.41
6.48
ug/l
0.44
11
88
5
26
1.95
0.71
1.2
1.3
—
—
—
0
0
60
516
1.28
0.70
3.0
2.3
74.25
77.84
nmol/l
0.50
52
459
34
271
1.33
0.70
1.4
1.3
4.64
1.40
u/ml
0.41
12
79
45
532
0.78
0.68
2.0
1.9
1.30
1.31
mmol/l
0.05
32
450
28
352
0.75
0.66
4.7
4.4
19.26
22.55
%
0.67
14
169
28
350
0.75
0.64
4.4
3.0
0.00
0.00
estimate
-0.00
12
100
112
1186
0.77
0.63
6.5
5.8
2.77
2.71
mmol/l
0.24
104
1101
5
30
1.69
0.62
1.0
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.4
—
1.04
—
0
13
0
20
0.00
0.61
0.0
1.4
—
1.00
—
0
13
0
20
0.00
0.61
0.0
1.4
—
1.22
—
0
13
16
116
1.43
0.57
6.0
3.0
—
—
—
0
0
10
65
1.58
0.57
2.5
2.0
—
—
—
0
0
9
132
0.66
0.55
4.2
2.4
—
—
—
0
0
89
820
1.22
0.51
5.6
3.0
61.78
47.88
u/l
0.58
82
773
17
128
1.37
0.50
14.4
7.3
—
—
—
0
0
27
223
1.26
0.44
1.4
1.9
452.68
452.27
pmol/l
0.00
22
188
18
142
1.30
0.41
1.6
1.9
1.82
1.47
%
0.70
13
126
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
25
207
1.25
0.40
2.2
1.6
—
—
—
0
0
38
433
0.83
0.39
6.3
5.3
1.31
1.97
ug/l
2.22
38
382
112
1166
0.83
0.36
5.3
5.0
1.47
1.46
mmol/l
0.10
104
1078
106
1108
0.84
0.36
7.8
6.0
39.93
38.91
mmol/mol
0.47
99
1041
110
1145
0.84
0.34
6.2
5.0
6.20
5.91
mmol/l
0.59
100
1052
23
270
0.82
0.32
3.0
3.1
0.50
0.78
ug/l
2.43
12
164
113
1171
0.85
0.31
5.6
5.1
4.67
4.62
mmol/l
0.17
106
1089
9
120
0.73
0.28
3.4
2.2
—
—
—
0
0
116
1122
1.16
0.26
29.2
13.1
81.36
81.17
ml/min/173m2
0.03
106
1032
124
1269
0.85
0.23
50.1
20.1
4.30
4.55
e12/l
5.42
119
1242
0
10
0.00
0.21
0.0
1.6
—
12.94
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
7
60
1.17
0.18
4.1
3.6
4.50
4.67
pmol/l
—
7
55
110
1077
1.08
0.12
6.1
5.1
1.84
1.94
mu/l
0.30
102
986
46
481
0.94
0.10
6.0
3.5
0.00
0.00
estimate
-0.00
14
103
109
1109
0.93
0.09
5.0
4.2
1.34
1.27
mmol/l
0.39
102
1018
6
56
1.07
0.09
1.3
1.4
—
—
—
0
0
41
402
1.03
0.02
6.8
3.5
17.76
6.53
mg/mmol
0.98
25
247
29
285
1.02
0.00
7.2
3.9
1.02
1.02
kg/l
0.47
18
192
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
68.50
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
29.53
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
98
0.91
-0.00
1.6
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_ACTINOMYCOSIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_ACTINOMYCOSIS | 2.689 [1.86, 3.89] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.106 |
During the follow-up period (1.1.1998 — 31.12.2019), 115 out of 379 females with AB1_ACTINOMYCOSIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_ACTINOMYCOSIS | 2.634 [1.72, 4.04] | < 0.001 |
| Birth year | 0.986 [0.92, 1.06] | 0.71 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 311 males with AB1_ACTINOMYCOSIS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_ACTINOMYCOSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.302% | 0.443% |
| 5 | 1.582% | 2.883% |
| 10 | 3.754% | 6.931% |
| 15 | 7.205% | 12.935% |
| 20 | 12.092% | 21.402% |
Relationships between endpoints
↥Index endpoint: AB1_ACTINOMYCOSIS – Actinomycosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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