Actinomycosis, including avohilmo

AB1_ACTINOMYCOSIS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A42
  • Hospital discharge: ICD-10 A42
  • Hospital discharge: ICD-9 03[9]
  • Hospital discharge: ICD-8 113
  • Cause of death: ICD-10 A42
  • Cause of death: ICD-9 03[9]
  • Cause of death: ICD-8 113

3 out of 7 registries used, show all original rules.

189

4. Check minimum number of events

None

189

5. Include endpoints

None

189

6. Filter based on genotype QC (FinnGen only)

159

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_BACTERIAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 159 84 75
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 56.32 52.62 60.45

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
168
Matched controls
1680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A42.8
ICD-10 Finland
Other forms of actinomycosis
+∞
44.8
41
*
A42.9
ICD-10 Finland
Actinomycosis, unspecified
+∞
33.5
31
*
A42.0
ICD-10 Finland
Pulmonary actinomycosis
+∞
32.3
30
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
46.8
28.4
34
9
A42.2
ICD-10 Finland
Cervicofacial actinomycosis
+∞
22.4
21
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.4
15.4
28
51
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
14.8
14
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
+∞
13.7
13
*
A46
ICD-10 Finland
Erysipelas
6.3
13.3
24
43
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.9
13.2
33
80
A42.7
ICD-10 Finland
Actinomycotic sepsis
+∞
11.6
11
*
JN4BD
NOMESCO Finland
Extensive body CT
4.7
10.6
27
66
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
10.5
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.7
9.5
24
58
A42
ICD-10 Finland
Actinomycosis
+∞
8.4
8
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
8.3
56
256
TGC00
NOMESCO Finland
Bronchial lavation
12.6
8.2
14
12
R50.9
ICD-10 Finland
Fever, unspecified
3.4
8.1
33
113
11399
ICD-8 Finland
Actinomycosis
+∞
7.3
7
*
A42.1
ICD-10 Finland
Abdominal actinomycosis
+∞
7.3
7
*
N02AA05
ATC
oxycodone; systemic
2.9
7.3
40
163
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
7.1
38
152
M04AA01
ATC
allopurinol; systemic
3.4
7.0
28
94
K05.31
ICD-10 Finland
Periodontitis pronounced
3.3
6.7
27
91
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
3.5
6.6
25
81
A06AD11
ATC
lactulose; oral
3.0
6.5
32
122
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
6.4
76
444
J01FF01
ATC
clindamycin; systemic
2.4
6.3
53
266
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
6.3
83
507
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
8.2
6.3
13
17
R2110
NOMESCO Finland
Giving the first information
4.4
6.2
16
39
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.6
6.2
17
33
TLC02
NOMESCO Finland
Simple extraction of IUD
7.7
6.1
13
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
62
5.00
11.46
8.1
1.7
7.41
7.42
ph
0.16
21
52
66
290
3.10
10.98
7.3
3.0
—
—
—
0
0
44
157
3.44
10.26
4.0
1.9
—
—
—
0
0
21
44
5.31
9.83
8.9
1.5
—
—
—
0
0
28
78
4.11
9.29
2.2
1.4
0.93
1.23
g/l
1.00
28
72
97
567
2.68
8.96
8.0
3.6
33.44
36.29
g/l
3.33
91
532
30
91
3.80
8.84
1.6
2.7
—
—
—
0
0
17
40
4.62
6.93
1.3
3.7
1.12
3.14
ratio
0.68
11
18
42
182
2.74
6.80
2.0
1.4
—
—
—
0
0
45
204
2.65
6.66
5.7
2.5
0.80
0.82
mmol/l
0.30
45
190
112
767
2.38
6.51
17.4
8.5
4.11
3.90
e9/l
0.51
100
669
73
424
2.28
6.21
11.9
4.7
—
—
—
0
0
103
690
2.27
6.18
13.2
5.0
0.61
0.56
e9/l
1.09
92
597
103
692
2.26
6.11
13.2
5.0
0.04
0.04
e9/l
0.45
92
597
97
646
2.19
5.75
12.8
5.9
1.22
1.22
mmol/l
0.19
85
562
9
7
13.49
5.65
1.6
2.0
35.39
41.71
%
—
9
7
9
7
13.49
5.65
2.6
1.7
—
—
—
0
0
27
102
2.96
5.57
7.3
3.5
0.00
0.25
%
0.48
11
16
103
710
2.16
5.50
13.8
5.1
1.74
1.89
e9/l
1.04
95
628
134
1029
2.49
5.49
16.3
6.7
86.57
76.80
u/l
0.84
128
961
10
11
9.58
5.36
1.4
1.2
—
—
—
0
0
103
719
2.12
5.21
13.3
5.1
0.21
0.18
e9/l
0.67
97
638
35
157
2.55
5.21
2.1
1.5
—
—
—
0
0
93
625
2.09
5.21
14.0
4.8
0.82
0.70
%
1.38
88
585
93
627
2.08
5.14
13.9
4.8
8.88
8.87
%
0.02
88
594
32
139
2.61
5.08
2.3
1.5
—
—
—
0
0
92
627
2.03
4.84
14.1
4.7
2.90
2.86
%
0.06
87
593
25
98
2.82
4.81
7.6
3.1
0.73
0.56
%
0.19
11
18
93
643
2.00
4.63
14.7
4.8
26.83
28.45
%
0.80
88
614
7
5
14.52
4.61
2.9
2.2
0.67
0.43
e9/l
—
7
5
13
28
4.94
4.47
1.2
1.1
—
—
—
0
0
23
91
2.77
4.35
1.6
1.5
—
—
—
0
0
24
99
2.66
4.20
7.9
3.3
0.00
0.18
%
—
9
17
14
42
3.55
4.14
1.3
1.5
—
—
—
0
0
7
7
10.36
4.05
5.1
3.3
10.39
10.60
mg/l
—
7
7
26
115
2.49
3.96
3.0
1.8
441.92
383.77
nmol/l
0.46
26
107
26
116
2.47
3.88
3.0
2.4
62.79
64.66
e9/l
0.15
17
80
11
24
4.83
3.82
1.4
1.3
—
—
—
0
0
24
104
2.53
3.81
8.0
3.3
0.80
0.70
%
—
10
22
39
210
2.12
3.77
2.0
1.6
—
—
—
0
0
74
504
1.84
3.59
5.5
3.6
31.24
52.10
ng/l
0.95
55
358
48
285
1.96
3.54
3.1
1.4
2.65
2.59
g/l
0.06
39
169
79
554
1.80
3.45
2.5
2.0
—
—
—
0
0
66
440
1.82
3.40
3.9
2.0
—
—
—
0
0
7
11
6.58
3.22
1.4
1.3
—
—
—
0
0
48
294
1.89
3.20
3.2
2.3
4.75
5.79
e6/l
0.32
42
266
9
20
4.69
3.16
2.0
1.2
—
—
—
0
0
22
101
2.36
3.09
9.1
9.7
—
—
—
0
0
8
16
5.19
3.09
5.8
2.4
4.98
4.04
e9/l
—
8
16
84
616
1.73
3.04
13.5
12.1
1.23
1.21
inr
0.13
71
493
5
5
10.25
2.99
1.0
1.0
—
—
—
0
0
40
237
1.90
2.93
2.3
2.1
—
—
—
0
0
22
104
2.28
2.90
1.9
1.3
—
—
—
0
0
31
170
2.01
2.83
10.6
7.3
103.97
103.80
mmol/l
0.09
31
170
5
6
8.54
2.76
1.0
1.0
—
—
—
0
0
7
14
5.17
2.76
1.0
3.9
—
—
—
0
0
8
19
4.37
2.71
4.0
2.0
—
—
—
0
0
81
603
1.66
2.67
17.8
9.3
0.00
0.00
e9/l
0.06
65
492
56
379
1.72
2.63
3.9
2.8
—
—
—
0
0
12
42
3.00
2.61
2.0
1.2
—
—
—
0
0
60
415
1.69
2.60
9.9
5.8
—
—
—
0
0
59
407
1.69
2.58
5.9
3.6
7.40
7.40
ph
0.01
51
283
33
193
1.88
2.50
1.9
1.4
328.89
620.44
titre
—
9
45
20
97
2.21
2.49
1.7
2.3
6.51
6.84
ug/l
0.03
14
85
9
27
3.46
2.43
5.4
2.0
61.44
56.44
%
—
9
27
5
8
6.40
2.39
1.0
1.0
—
—
—
0
0
64
459
1.64
2.38
6.5
2.8
2.34
2.36
mmol/l
0.67
57
423
21
107
2.10
2.33
7.5
8.4
1.11
1.29
mmol/l
0.42
21
107
49
333
1.67
2.23
3.7
2.5
323.46
338.98
umol/l
0.55
41
292
5
9
5.69
2.23
1.0
1.0
—
—
—
0
0
82
635
1.57
2.17
3.7
2.9
212.19
97.13
ug/l
2.07
72
590
9
31
3.01
2.10
4.8
1.9
7.38
7.42
ph
—
9
31
67
499
1.57
2.08
4.7
3.7
30.13
63.52
e6/l
1.08
49
343
5
10
5.11
2.08
1.4
1.0
—
—
—
0
0
44
296
1.66
2.07
1.7
1.7
1.53
1.14
mg/l
0.37
36
240
38
246
1.70
2.06
3.5
2.5
500.09
540.33
mosm/kgh2o
0.55
33
209
60
441
1.56
1.96
4.0
3.0
36.56
194.10
e6/l
0.52
49
325
5
11
4.65
1.95
1.4
1.6
22.60
51.00
ng/l
—
5
11
6
16
3.85
1.95
2.8
1.6
—
—
—
0
0
7
22
3.27
1.90
1.0
1.0
—
—
—
0
0
6
17
3.62
1.85
1.5
1.3
—
—
—
0
0
6
17
3.62
1.85
1.5
1.3
—
—
—
0
0
6
17
3.62
1.85
1.5
1.3
—
—
—
0
0
6
17
3.62
1.85
1.5
1.3
—
—
—
0
0
41
279
1.62
1.83
4.4
2.5
2.46
2.44
mmol/l
0.39
34
255
9
35
2.66
1.83
1.0
1.4
—
—
—
0
0
13
60
2.26
1.83
1.0
1.2
—
—
—
0
0
7
23
3.13
1.82
6.4
2.0
10.06
8.21
pmol/l
—
7
23
7
24
3.00
1.74
1.9
1.6
—
—
—
0
0
52
381
1.53
1.69
4.0
2.9
0.17
0.35
e6/l
1.29
41
262
73
578
1.47
1.62
2.2
2.0
91.68
97.87
pmol/l
0.68
41
302
15
78
2.01
1.60
10.1
8.2
26.99
24.90
mmol/l
0.99
15
78
7
26
2.76
1.60
1.0
1.4
—
—
—
0
0
7
26
2.76
1.60
1.1
1.3
—
—
—
0
0
6
20
3.07
1.59
1.2
1.1
—
—
—
0
0
6
20
3.07
1.59
1.2
1.1
—
—
—
0
0
5
15
3.40
1.53
1.8
1.3
—
—
—
0
0
19
111
1.80
1.46
6.4
2.7
3.45
1.93
mmol/l
0.87
19
99
78
635
1.43
1.46
4.0
2.4
—
—
estimate
—
0
0
15
81
1.94
1.45
10.9
11.0
0.60
0.64
%
0.18
15
81
5
16
3.19
1.45
1.0
1.1
—
—
—
0
0
7
29
2.47
1.41
2.0
1.6
123.43
226.63
ug/l
—
7
29
9
41
2.26
1.39
1.1
1.2
—
—
—
0
0
144
1322
1.62
1.39
36.2
12.5
28.58
22.04
mg/l
1.51
126
1050
6
23
2.67
1.38
1.0
1.0
—
—
—
0
0
5
17
3.00
1.37
1.0
1.0
—
—
—
0
0
15
83
1.89
1.36
11.1
10.6
1.40
1.35
%
0.09
15
83
11
54
2.11
1.36
1.3
1.3
—
—
—
0
0
11
54
2.11
1.36
1.2
1.3
—
—
—
0
0
51
390
1.44
1.32
1.8
1.6
22.23
20.93
nmol/l
0.30
42
330
6
24
2.55
1.31
1.7
1.2
—
—
—
0
0
6
24
2.55
1.31
3.8
1.8
5.52
5.01
kpa
—
6
24
6
24
2.55
1.31
3.8
1.8
7.18
8.70
kpa
—
6
24
10
48
2.15
1.30
1.5
1.3
1.24
1.20
g/l
—
10
48
10
48
2.15
1.30
2.5
1.3
0.24
0.23
g/l
—
10
48
44
328
1.46
1.29
1.4
1.3
4.29
1.40
u/ml
0.39
13
91
118
1048
1.42
1.27
4.6
4.2
15.11
14.69
pmol/l
0.97
107
955
43
322
1.45
1.23
11.8
4.0
—
—
—
0
0
11
57
1.99
1.20
6.6
3.5
37.06
36.97
°c
0.47
11
57
26
177
1.55
1.17
1.7
1.8
116.15
77.70
ug/g
0.53
20
141
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
5
20
2.54
1.16
1.8
1.1
—
—
—
0
0
11
58
1.96
1.15
1.0
1.1
—
—
—
0
0
13
74
1.82
1.10
9.6
11.1
26.20
24.61
mmol/l
0.71
13
74
5
21
2.42
1.10
1.0
1.2
—
—
—
0
0
18
115
1.63
1.04
6.4
2.8
7.39
7.38
ph
—
10
59
7
34
2.10
1.04
6.7
3.9
4.11
3.92
mmol/l
—
7
34
48
380
1.37
1.00
5.6
3.9
0.00
0.01
estimate
0.50
16
135
10
54
1.91
0.99
1.1
1.3
—
—
—
0
0
82
706
1.32
0.97
4.9
3.7
0.00
0.00
estimate
-0.00
18
146
24
168
1.50
0.96
2.8
2.6
3.92
5.93
e9/l
0.78
19
149
9
51
1.81
0.96
1.2
1.3
—
—
—
0
0
29
212
1.44
0.95
3.1
3.0
1.69
2.48
e6/l
0.26
13
96
6
27
2.27
0.94
1.3
1.2
—
—
—
0
0
15
94
1.65
0.94
4.3
3.1
—
—
—
0
0
19
127
1.56
0.93
4.8
5.1
4.14
5.90
ug/l
0.45
14
102
18
119
1.57
0.92
1.1
1.1
—
—
—
0
0
10
56
1.84
0.90
1.2
1.3
—
—
—
0
0
25
181
1.45
0.86
1.4
1.2
—
—
—
0
0
82
715
1.29
0.86
5.0
3.7
0.00
10.83
estimate
0.50
18
150
82
719
1.27
0.81
5.2
3.7
0.00
0.00
estimate
-0.00
15
143
11
66
1.71
0.81
7.2
2.8
24.76
24.79
mmol/l
0.00
11
66
67
573
1.28
0.80
4.6
3.3
6.48
6.19
ph
0.96
31
333
90
800
1.27
0.78
7.2
4.4
6.69
6.47
mmol/l
0.53
90
751
19
133
1.48
0.77
2.5
2.0
—
—
—
0
0
6
34
1.79
0.77
2.8
1.9
—
—
—
0
0
9
146
0.59
0.73
1.7
1.5
—
—
—
0
0
32
254
1.32
0.66
1.4
1.4
29.88
8.29
u/ml
0.48
11
109
33
406
0.77
0.65
4.2
3.0
0.00
0.00
estimate
-0.00
14
116
130
1368
0.78
0.62
6.3
5.7
2.73
2.73
mmol/l
0.02
120
1265
20
149
1.39
0.61
8.9
8.4
7.42
7.41
ph
0.15
11
89
32
259
1.29
0.58
1.4
1.9
443.79
447.50
pmol/l
0.03
24
218
6
35
1.74
0.58
1.7
1.1
618.17
472.11
mg/l
—
6
35
34
278
1.28
0.57
1.4
1.3
62.07
29.14
iu/ml
—
7
86
10
66
1.55
0.54
1.3
1.2
—
—
—
0
0
15
109
1.41
0.53
2.4
2.1
5.17
0.23
e6/l
0.46
15
102
48
543
0.84
0.44
3.4
3.1
—
—
—
0
0
10
138
0.71
0.42
1.3
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
6.35
—
0
5
0
17
0.00
0.41
0.0
1.0
—
3.29
—
0
6
123
1278
0.86
0.33
7.4
5.9
39.63
38.77
mmol/mol
0.44
116
1196
130
1345
0.85
0.33
5.2
4.9
1.48
1.47
mmol/l
0.04
120
1241
40
447
0.86
0.31
7.4
5.2
1.42
1.97
ug/l
1.52
40
394
55
599
0.88
0.30
1.9
1.9
1.30
1.32
mmol/l
0.06
40
510
51
555
0.88
0.27
5.7
3.5
0.00
0.00
estimate
-0.00
16
120
29
328
0.86
0.26
7.2
3.8
1.02
1.02
kg/l
0.46
18
217
129
1249
1.14
0.26
5.9
5.2
1.79
1.92
mu/l
0.52
120
1147
9
77
1.18
0.25
4.0
3.8
4.71
4.62
pmol/l
—
9
71
5
37
1.36
0.24
1.2
1.2
—
112.00
—
0
5
11
135
0.80
0.23
1.9
1.7
—
—
—
0
0
5
40
1.26
0.22
1.2
1.2
—
—
—
0
0
51
475
1.11
0.20
4.6
2.9
6.25
8.08
mmol/l
1.62
41
394
132
1351
0.89
0.20
5.4
5.0
4.65
4.64
mmol/l
0.03
123
1255
6
51
1.18
0.19
1.5
2.7
—
—
—
0
0
14
164
0.84
0.19
1.0
1.3
—
—
—
0
0
25
278
0.88
0.18
2.8
3.1
0.69
0.78
ug/l
0.17
13
169
7
60
1.17
0.18
2.1
1.8
—
—
—
0
0
8
69
1.17
0.16
1.5
1.8
—
—
—
0
0
136
1385
0.91
0.15
27.5
11.2
—
—
—
0
0
145
1469
0.91
0.12
47.6
20.0
4.30
4.53
e12/l
5.66
140
1440
42
399
1.07
0.10
1.8
1.5
—
—
—
0
0
126
1281
0.93
0.10
4.8
4.1
1.32
1.27
mmol/l
0.33
117
1174
5
60
0.83
0.08
3.8
5.0
1.24
1.75
%
—
5
55
15
138
1.10
0.06
1.3
1.4
—
—
—
0
0
131
1316
0.98
0.00
6.0
4.9
6.21
5.88
mmol/l
0.82
120
1208
18
179
1.01
0.00
1.1
1.3
—
—
—
0
0
45
445
1.02
0.00
5.3
3.0
82.32
41.53
mg/l
0.78
31
288
45
452
0.99
0.00
6.3
3.5
17.52
6.99
mg/mmol
0.95
26
277
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.4
—
4.85
—
0
8
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
26.60
—
0
5
0
9
0.00
-0.00
0.0
8.4
—
0.60
—
0
9
9
95
0.94
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
140.20
—
0
5
0
9
0.00
-0.00
0.0
2.2
—
68.11
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.3
1.2
1.49
1.54
g/l
—
6
60
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
158.11
—
0
8
8
81
0.99
-0.00
6.6
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
10.22
—
0
5

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_ACTINOMYCOSIS_WIDE – Actinomycosis, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).