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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Other changes in lacrimal passages

H7_LACRIPAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H04.6
  • Hospital discharge: ICD-9 3756
  • Hospital discharge: ICD-8 36805
  • Cause of death: ICD-10 H04.6
  • Cause of death: ICD-9 3756
  • Cause of death: ICD-8 36805

2 out of 7 registries used, show all original rules.

52

4. Check minimum number of events

None

52

5. Include endpoints

None

52

6. Filter based on genotype QC (FinnGen only)

47

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H04
Name in latin
Aliae morbositates apparati lacrimalis

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 334 214 120
Only index persons 291 191 100
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population - 54.59 38.23
Only index persons 49.58 54.40 40.38

-FinnGen-

Key figures

All Female Male
Number of individuals 47 40 7
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 52.80 55.53 37.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
52
Matched controls
520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A98, ,
ICD-O-3
+∞
71.7
51
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
62.9
47
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
62.9
47
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
62.9
47
*
J01DB01, ,
ATC
cefalexin; oral
+∞
62.9
47
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
53.8
42
*
H046, ,
ICD-10 Finland
Other changes in lacrimal passages
+∞
52.1
41
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
48.9
39
*
M03BX02, ,
ATC
tizanidine; oral
+∞
47.3
38
*
SAA01, ,
ICD-O-3
+∞
44.2
36
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
44.2
36
*
WX110, ,
ICD-O-3
+∞
42.7
35
*
SAA02, ,
ICD-O-3
+∞
42.7
35
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
41.2
34
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
41.2
34
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
39.8
33
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
36.9
31
*
SFA20, ,
ICD-O-3
+∞
36.9
31
*
EB1AA, ,
ICD-O-3
+∞
36.9
31
*
K021, ,
ICD-O-3
+∞
34.2
29
*
KMAK, ,
ICD-O-3
+∞
34.2
29
*
J01DA01, ,
ATC
[U] cefalexin
+∞
32.8
28
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
32.8
28
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
32.8
28
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
32.8
28
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
32.8
28
*
R01AD09, ,
ATC
mometasone; nasal
+∞
31.5
27
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
31.5
27
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
31.5
27
*
R06AE07, ,
ATC
cetirizine; oral
+∞
30.1
26
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
30.1
26
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
30.1
26
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
30.1
26
*
SFA10, ,
ICD-O-3
+∞
30.1
26
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
28.8
25
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
28.8
25
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
27.5
24
*
GD1AA, ,
ICD-O-3
+∞
27.5
24
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
27.5
24
*
Z012, ,
ICD-O-3
+∞
27.5
24
*
J069, ,
ICD-O-3
+∞
27.5
24
*
S18, ,
ICD-O-3
+∞
27.5
24
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
26.3
23
*
EB1SA, ,
ICD-O-3
+∞
26.3
23
*
WZB00, ,
ICD-O-3
+∞
25.0
22
*
Z871, ,
ICD-O-3
+∞
25.0
22
*
ZXE00, ,
ICD-O-3
+∞
25.0
22
*
M796, ,
ICD-O-3
+∞
25.0
22
*
E0000UV, ,
ATC
+∞
25.0
22
*
K0364, ,
ICD-O-3
+∞
23.8
21
*
WYA05, ,
ICD-O-3
+∞
23.8
21
*
EB1HA, ,
ICD-O-3
+∞
23.8
21
*
L17, ,
ICD-O-3
+∞
23.8
21
*
SAA03, ,
ICD-O-3
+∞
23.8
21
*
SFA30, ,
ICD-O-3
+∞
23.8
21
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
23.8
21
*
R4110, ,
ICD-O-3
+∞
22.5
20
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
22.5
20
*
R05, ,
ICD-O-3
+∞
22.5
20
*
-1, ,
ICD-O-3
+∞
22.5
20
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
22.5
20
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
22.5
20
*
R74, ,
ICD-O-3
+∞
22.5
20
*
SDA03, ,
ICD-O-3
+∞
22.5
20
*
SDA01, ,
ICD-O-3
+∞
21.3
19
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
21.3
19
*
SPAT1263, ,
ICD-O-3
+∞
21.3
19
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
21.3
19
*
ZXA00, ,
ICD-O-3
+∞
21.3
19
*
I10, ,
ICD-O-3
+∞
21.3
19
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
21.3
19
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
21.3
19
*
M02AA07, ,
ATC
piroxicam; topical
+∞
20.1
18
*
CJE20, ,
ICD-O-3
+∞
20.1
18
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
20.1
18
*
ZXD10, ,
ICD-O-3
+∞
20.1
18
*
WX290, ,
ICD-O-3
+∞
18.9
17
*
ZXE10, ,
ICD-O-3
+∞
18.9
17
*
M255, ,
ICD-O-3
+∞
18.9
17
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
18.9
17
*
H251, ,
ICD-10 Finland
Senile nuclear cataract
+∞
18.9
17
*
Z2221, ,
ICD-O-3
+∞
18.9
17
*
Z760, ,
ICD-O-3
+∞
18.9
17
*
VALMI, ,
ICD-O-3
+∞
18.9
17
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
17.7
16
*
SDA02, ,
ICD-O-3
+∞
17.7
16
*
M545, ,
ICD-O-3
+∞
17.7
16
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
17.7
16
*
SPAT1325, ,
ICD-O-3
+∞
17.7
16
*
LC2BE, ,
ICD-O-3
+∞
17.7
16
*
D82, ,
ICD-O-3
+∞
17.7
16
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
17.7
16
*
D07AC13, ,
ATC
mometasone; topical
+∞
17.7
16
*
D07AC01, ,
ATC
betamethasone; topical
+∞
17.7
16
*
D19, ,
ICD-O-3
+∞
17.7
16
*
AA1AD, ,
ICD-O-3
+∞
17.7
16
*
ZXA05, ,
ICD-O-3
+∞
17.7
16
*
WX320, ,
ICD-O-3
+∞
17.7
16
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
17.7
16
*
M01AX05, ,
ATC
glucosamine; oral
+∞
16.5
15
*
SDE02, ,
ICD-O-3
+∞
16.5
15
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
16.5
15
*
M03BC51, ,
ATC
orphenadrine, combinations; systemic
+∞
16.5
15
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
16.5
15
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
16.5
15
*
Z718, ,
ICD-O-3
+∞
16.5
15
*
SPAT1249, ,
ICD-O-3
+∞
16.5
15
*
M255, ,
ICD-10 Finland
Pain in joint
+∞
16.5
15
*
R53, ,
ICD-O-3
+∞
16.5
15
*
EBA00, ,
ICD-O-3
+∞
16.5
15
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
16.5
15
*
R104, ,
ICD-O-3
+∞
16.5
15
*
UJD10, ,
ICD-O-3
+∞
16.5
15
*
R42, ,
ICD-10 Finland
Dizziness and giddiness
+∞
16.5
15
*
WZC00, ,
ICD-O-3
+∞
16.5
15
*
C09CA06, ,
ATC
candesartan; oral
+∞
16.5
15
*
WX408, ,
ICD-O-3
+∞
15.3
14
*
SPAT1223, ,
ICD-O-3
+∞
15.3
14
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
15.3
14
*
H045, ,
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
+∞
15.3
14
*
WX404, ,
ICD-O-3
+∞
15.3
14
*
SPAT1253, ,
ICD-O-3
+∞
15.3
14
*
C08CA01, ,
ATC
amlodipine; oral
+∞
15.3
14
*
Z712, ,
ICD-O-3
+∞
15.3
14
*
A28, ,
ICD-O-3
+∞
15.3
14
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
15.3
14
*
ZXD05, ,
ICD-O-3
+∞
15.3
14
*
SPAT1310, ,
ICD-O-3
+∞
15.3
14
*
R103, ,
ICD-10 Finland
Pain localized to other parts of lower abdomen
+∞
15.3
14
*
R83, ,
ICD-O-3
+∞
15.3
14
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
15.3
14
*
SPAT1256, ,
ICD-O-3
+∞
15.3
14
*
A10BA02, ,
ATC
metformin; oral
+∞
15.3
14
*
L15, ,
ICD-O-3
+∞
15.3
14
*
SCA01, ,
ICD-O-3
+∞
14.2
13
*
E000001, ,
ATC
+∞
14.2
13
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
14.2
13
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
14.2
13
*
SFA40, ,
ICD-O-3
+∞
14.2
13
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
14.2
13
*
R03DC03, ,
ATC
montelukast; oral
+∞
14.2
13
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
14.2
13
*
SPAT1312, ,
ICD-O-3
+∞
14.2
13
*
N06AB04, ,
ATC
citalopram; systemic
+∞
14.2
13
*
Z017, ,
ICD-O-3
+∞
14.2
13
*
Z3226, ,
ICD-O-3
+∞
14.2
13
*
Z3231, ,
ICD-O-3
+∞
14.2
13
*
J05AB01, ,
ATC
aciclovir; systemic
+∞
14.2
13
*
H02AB07, ,
ATC
prednisone; oral
+∞
14.2
13
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
14.2
13
*
OAB43, ,
ICD-O-3
+∞
14.2
13
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
13.0
12
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
13.0
12
*
ZXA10, ,
ICD-O-3
+∞
13.0
12
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
13.0
12
*
SPAT1260, ,
ICD-O-3
+∞
13.0
12
*
L03, ,
ICD-O-3
+∞
13.0
12
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
13.0
12
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
13.0
12
*
R06AE09, ,
ATC
levocetirizine; oral
+∞
13.0
12
*
N05CF01, ,
ATC
zopiclone; oral
+∞
13.0
12
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
13.0
12
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
13.0
12
*
NG1AA, ,
ICD-O-3
+∞
13.0
12
*
M01AX17, ,
ATC
nimesulide; oral
+∞
13.0
12
*
N02AA05, ,
ATC
oxycodone; systemic
+∞
13.0
12
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
13.0
12
*
N05BA04, ,
ATC
oxazepam; oral
+∞
13.0
12
*
J209, ,
ICD-O-3
+∞
13.0
12
*
C03CA01, ,
ATC
furosemide; systemic
+∞
13.0
12
*
R5110, ,
ICD-O-3
+∞
13.0
12
*
K045, ,
ICD-O-3
+∞
13.0
12
*
SPAT1301, ,
ICD-O-3
+∞
13.0
12
*
J010, ,
ICD-O-3
+∞
13.0
12
*
C10AA01, ,
ATC
simvastatin; oral
+∞
13.0
12
*
L08, ,
ICD-O-3
+∞
11.9
11
*
J01MA06, ,
ATC
norfloxacin; oral
+∞
11.9
11
*
GD1UA, ,
ICD-O-3
+∞
11.9
11
*
WZA90, ,
ICD-O-3
+∞
11.9
11
*
M751, ,
ICD-O-3
+∞
11.9
11
*
K0365, ,
ICD-O-3
+∞
11.9
11
*
J459, ,
ICD-10 Finland
Asthma, unspecified
+∞
11.9
11
*
M171, ,
ICD-10 Finland
Other primary gonarthrosis
+∞
11.9
11
*
R06AX27, ,
ATC
desloratadine; oral
+∞
11.9
11
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
11.9
11
*
215, ,
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
11.9
11
*
R03AK07, ,
ATC
formoterol and budesonide; inhalant
+∞
11.9
11
*
F510, ,
ICD-O-3
+∞
11.9
11
*
R02, ,
ICD-O-3
+∞
11.9
11
*
R21, ,
ICD-O-3
+∞
11.9
11
*
WX402, ,
ICD-O-3
+∞
11.9
11
*
Z024, ,
ICD-O-3
+∞
11.9
11
*
K0382, ,
ICD-O-3
+∞
11.9
11
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
11.9
11
*
A03, ,
ICD-O-3
+∞
11.9
11
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
11.9
11
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
11.9
11
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
11.9
11
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
11.9
11
*
103, ,
Kela drug reimbursment
Diabetes, insulin-treated
+∞
11.9
11
*
TPH04, ,
ICD-O-3
+∞
10.8
10
*
A01, ,
ICD-O-3
+∞
10.8
10
*
R06AX22, ,
ATC
ebastine; oral
+∞
10.8
10
*
D01, ,
ICD-O-3
+∞
10.8
10
*
D11, ,
ICD-O-3
+∞
10.8
10
*
NB1AA, ,
ICD-O-3
+∞
10.8
10
*
S21, ,
ICD-O-3
+∞
10.8
10
*
R03AC03, ,
ATC
terbutaline; inhalant
+∞
10.8
10
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
10.8
10
*
L13, ,
ICD-O-3
+∞
10.8
10
*
UJF32, ,
ICD-O-3
+∞
10.8
10
*
WX002, ,
ICD-O-3
+∞
10.8
10
*
M54, ,
ICD-O-3
+∞
10.8
10
*
D07AA02, ,
ATC
hydrocortisone; topical
+∞
10.8
10
*
F29, ,
ICD-O-3
+∞
10.8
10
*
SDE03, ,
ICD-O-3
+∞
10.8
10
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
10.8
10
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
10.8
10
*
R01AD01, ,
ATC
beclometasone; nasal
+∞
10.8
10
*
FM1EE, ,
ICD-O-3
+∞
10.8
10
*
M791, ,
ICD-O-3
+∞
10.8
10
*
D07AD01, ,
ATC
clobetasol; topical
+∞
10.8
10
*
M02AA10, ,
ATC
ketoprofen; topical
+∞
10.8
10
*
C07AA05, ,
ATC
propranolol; systemic
+∞
10.8
10
*
H100, ,
ICD-O-3
+∞
10.8
10
*
M01AG02, ,
ATC
tolfenamic acid; oral, rectal
+∞
10.8
10
*
SPAT1254, ,
ICD-O-3
+∞
9.7
9
*
H01, ,
ICD-O-3
+∞
9.7
9
*
NA3BG, ,
ICD-O-3
+∞
9.7
9
*
A97, ,
ICD-O-3
+∞
9.7
9
*
XF400, ,
ICD-O-3
+∞
9.7
9
*
WX105, ,
ICD-O-3
+∞
9.7
9
*
E039, ,
ICD-10 Finland
Hypothyroidism, unspecified
+∞
9.7
9
*
SPAT1250, ,
ICD-O-3
+∞
9.7
9
*
Z015, ,
ICD-10 Finland
Diagnostic skin and sensitization tests
+∞
9.7
9
*
R074, ,
ICD-O-3
+∞
9.7
9
*
XCC00, ,
ICD-O-3
+∞
9.7
9
*
H0410, ,
ICD-10 Finland
Dry eye syndrome
+∞
9.7
9
*
S29, ,
ICD-O-3
+∞
9.7
9
*
SFC01, ,
ICD-O-3
+∞
9.7
9
*
C09AA05, ,
ATC
ramipril; oral
+∞
9.7
9
*
AA1BG, ,
ICD-O-3
+∞
9.7
9
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
9.7
9
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
9.7
9
*
SFA00, ,
ICD-O-3
+∞
9.7
9
*
N03AX16, ,
ATC
[U] pregabalin
+∞
9.7
9
*
N300, ,
ICD-O-3
+∞
9.7
9
*
M751, ,
ICD-10 Finland
Rotator cuff syndrome
+∞
9.7
9
*
SPAT1306, ,
ICD-O-3
+∞
9.7
9
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
9.7
9
*
R06AX13, ,
ATC
loratadine; oral
+∞
9.7
9
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
9.7
9
*
M232, ,
ICD-10 Finland
Derangement of meniscus due to old tear or injury
+∞
9.7
9
*
R101, ,
ICD-O-3
+∞
9.7
9
*
SDA04, ,
ICD-O-3
+∞
9.7
9
*
SPAT1283, ,
ICD-O-3
+∞
9.7
9
*
I251, ,
ICD-10 Finland
Atherosclerotic heart disease
+∞
9.7
9
*
JN3AD, ,
ICD-O-3
+∞
9.7
9
*
J01DA06, ,
ATC
[U] cefuroxime
+∞
9.7
9
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
9.7
9
*
H438, ,
ICD-10 Finland
Other disorders of vitreous body
+∞
8.6
8
*
G01AA10, ,
ATC
clindamycin; vaginal
+∞
8.6
8
*
L309, ,
ICD-O-3
+∞
8.6
8
*
Z363, ,
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
+∞
8.6
8
*
H02AB04, ,
ATC
methylprednisolone; systemic
+∞
8.6
8
*
SPAT1153, ,
ICD-O-3
+∞
8.6
8
*
ND2AA, ,
ICD-O-3
+∞
8.6
8
*
A02BA02, ,
ATC
ranitidine; systemic
+∞
8.6
8
*
M01AH01, ,
ATC
celecoxib; oral
+∞
8.6
8
*
T90, ,
ICD-O-3
+∞
8.6
8
*
K020, ,
ICD-O-3
+∞
8.6
8
*
WX700, ,
ICD-O-3
+∞
8.6
8
*
C07AB02, ,
ATC
metoprolol; systemic
+∞
8.6
8
*
R529, ,
ICD-O-3
+∞
8.6
8
*
N05BA01, ,
ATC
diazepam; systemic, rectal
+∞
8.6
8
*
Z014, ,
ICD-O-3
+∞
8.6
8
*
R42, ,
ICD-O-3
+∞
8.6
8
*
H81, ,
ICD-O-3
+∞
8.6
8
*
L28, ,
ICD-O-3
+∞
8.6
8
*
R53, ,
ICD-10 Finland
Malaise and fatigue
+∞
8.6
8
*
R103, ,
ICD-O-3
+∞
8.6
8
*
FM1AE, ,
ICD-O-3
+∞
8.6
8
*
J01AA07, ,
ATC
tetracycline; systemic
+∞
8.6
8
*
FN1AC, ,
ICD-O-3
+∞
8.6
8
*
Z014, ,
ICD-10 Finland
Gynaecological examination (general)(routine)
+∞
8.6
8
*
SPAT1222, ,
ICD-O-3
+∞
8.6
8
*
L12, ,
ICD-O-3
+∞
8.6
8
*
A04, ,
ICD-O-3
+∞
8.6
8
*
G442, ,
ICD-O-3
+∞
8.6
8
*
N06AB03, ,
ATC
fluoxetine; oral
+∞
8.6
8
*
K573, ,
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
+∞
8.6
8
*
N05AH04, ,
ATC
quetiapine; oral
+∞
8.6
8
*
G03DA02, ,
ATC
medroxyprogesterone; systemic
+∞
8.6
8
*
T814, ,
ICD-10 Finland
Infection following a procedure, not elsewhere classified
+∞
8.6
8
*
E039, ,
ICD-O-3
+∞
8.6
8
*
J450, ,
ICD-10 Finland
Predominantly allergic asthma
+∞
8.6
8
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
8.6
8
*
NH3AA, ,
ICD-O-3
+∞
8.6
8
*
C01DA14, ,
ATC
isosorbide mononitrate; oral
+∞
8.6
8
*
JN3AE, ,
ICD-O-3
+∞
8.6
8
*
C05AA08, ,
ATC
fluocortolone; rectal, topical
+∞
8.6
8
*
R101, ,
ICD-10 Finland
Pain localized to upper abdomen
+∞
8.6
8
*
WZC30, ,
ICD-O-3
+∞
8.6
8
*
N760, ,
ICD-O-3
+∞
8.6
8
*
3756X, ,
ICD-9 Finland
Disorders of lachrymal system, Other changes of lachrymal passages
+∞
7.5
7
*
M544, ,
ICD-O-3
+∞
7.5
7
*
B01AC04, ,
ATC
clopidogrel; oral
+∞
7.5
7
*
SPAT1053, ,
ICD-O-3
+∞
7.5
7
*
65000, ,
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
7.5
7
*
E119, ,
ICD-10 Finland
Type 2 diabetes mellitus, without complications
+∞
7.5
7
*
O800, ,
ICD-10 Finland
Spontaneous vertex delivery
+∞
7.5
7
*
104, ,
Kela drug reimbursment
Thyroid insufficiency
+∞
7.5
7
*
L11, ,
ICD-O-3
+∞
7.5
7
*
XLD00, ,
ICD-O-3
+∞
7.5
7
*
F3210, ,
ICD-10 Finland
Moderate depressive episode without somatic syndrome
+∞
7.5
7
*
C09CA01, ,
ATC
losartan; oral
+∞
7.5
7
*
N05CD07, ,
ATC
temazepam; oral
+∞
7.5
7
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
7.5
7
*
JN1AE, ,
ICD-O-3
+∞
7.5
7
*
P20, ,
ICD-O-3
+∞
7.5
7
*
MA2HE, ,
ICD-O-3
+∞
7.5
7
*
205, ,
Kela drug reimbursment
Chronic hypertension
+∞
7.5
7
*
290, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
7.5
7
*
SPAT1262, ,
ICD-O-3
+∞
7.5
7
*
SPAT1216, ,
ICD-O-3
+∞
7.5
7
*
N950, ,
ICD-10 Finland
Postmenopausal bleeding
+∞
7.5
7
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
7.5
7
*
R238, ,
ICD-O-3
+∞
7.5
7
*
I48, ,
ICD-10 Finland
Atrial fibrillation and flutter
+∞
7.5
7
*
N390, ,
ICD-10 Finland
Urinary tract infection, site not specified
+∞
7.5
7
*
R5180, ,
ICD-10 Finland
Headache
+∞
7.5
7
*
LCA06, ,
ICD-O-3
+∞
7.5
7
*
WX100, ,
ICD-O-3
+∞
7.5
7
*
N05CF02, ,
ATC
zolpidem; oral
+∞
7.5
7
*
G01AF05, ,
ATC
econazole; vaginal
+∞
7.5
7
*
B01AA03, ,
ATC
warfarin; systemic
+∞
7.5
7
*
JN3BD, ,
ICD-O-3
+∞
7.5
7
*
XCW99, ,
ICD-O-3
+∞
7.5
7
*
N390, ,
ICD-O-3
+∞
7.5
7
*
S82, ,
ICD-O-3
+∞
7.5
7
*
QAE10, ,
ICD-O-3
+∞
7.5
7
*
E000002, ,
ATC
+∞
7.5
7
*
C03EA01, ,
ATC
hydrochlorothiazide and potassium-sparing agents; oral
+∞
7.5
7
*
N01, ,
ICD-O-3
+∞
7.5
7
*
WYA10, ,
ICD-O-3
+∞
7.5
7
*
N02AE01, ,
ATC
buprenorphine; parenteral, sublingual, transdermal
+∞
7.5
7
*
S060, ,
ICD-10 Finland
Concussion
+∞
7.5
7
*
N06AX21, ,
ATC
duloxetine; oral
+∞
7.5
7
*
M480, ,
ICD-10 Finland
Spinal stenosis
+∞
7.5
7
*
351, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
7.5
7
*
U02, ,
ICD-O-3
+∞
7.5
7
*
UKC02, ,
ICD-O-3
+∞
7.5
7
*
E119, ,
ICD-O-3
+∞
7.5
7
*
GD1QA, ,
ICD-O-3
+∞
7.5
7
*
Z258, ,
ICD-O-3
+∞
7.5
7
*
NA1AD, ,
ICD-O-3
+∞
7.5
7
*
M531, ,
ICD-O-3
+∞
7.5
7
*
B02AA02, ,
ATC
tranexamic acid; systemic
+∞
7.5
7
*
N06AX16, ,
ATC
venlafaxine; oral
+∞
7.5
7
*
WW200, ,
ICD-O-3
+∞
7.5
7
*
D01BA02, ,
ATC
terbinafine; oral
+∞
7.5
7
*
R13, ,
ICD-10 Finland
Dysphagia
+∞
6.4
6
*
Z961, ,
ICD-10 Finland
Presence of intraocular lens
+∞
6.4
6
*
114, ,
Kela drug reimbursment
Glaucoma
+∞
6.4
6
*
UJF30, ,
ICD-O-3
+∞
6.4
6
*
PH2AE, ,
ICD-O-3
+∞
6.4
6
*
L02, ,
ICD-O-3
+∞
6.4
6
*
H660, ,
ICD-O-3
+∞
6.4
6
*
M02AA15, ,
ATC
diclofenac; topical
+∞
6.4
6
*
H264, ,
ICD-10 Finland
After-cataract
+∞
6.4
6
*
R03AK06, ,
ATC
salmeterol and fluticasone; inhalant
+∞
6.4
6
*
M17, ,
ICD-O-3
+∞
6.4
6
*
Z016, ,
ICD-O-3
+∞
6.4
6
*
B01AF02, ,
ATC
apixaban; oral
+∞
6.4
6
*
J05AB11, ,
ATC
valaciclovir; oral
+∞
6.4
6
*
A09, ,
ICD-O-3
+∞
6.4
6
*
J20, ,
ICD-O-3
+∞
6.4
6
*
K0510, ,
ICD-O-3
+∞
6.4
6
*
OAA65, ,
ICD-O-3
+∞
6.4
6
*
M161, ,
ICD-10 Finland
Other primary coxarthrosis
+∞
6.4
6
*
A01AB09, ,
ATC
miconazole; local oral
+∞
6.4
6
*
B01AF01, ,
ATC
rivaroxaban; oral
+∞
6.4
6
*
I839, ,
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
+∞
6.4
6
*
R03BA08, ,
ATC
ciclesonide; inhalant
+∞
6.4
6
*
J189, ,
ICD-O-3
+∞
6.4
6
*
L84, ,
ICD-O-3
+∞
6.4
6
*
R03BA01, ,
ATC
beclometasone; inhalant
+∞
6.4
6
*
H045, ,
ICD-O-3
+∞
6.4
6
*
J320, ,
ICD-10 Finland
Chronic maxillary sinusitis
+∞
6.4
6
*
C01DA02, ,
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
+∞
6.4
6
*
SPAT1230, ,
ICD-O-3
+∞
6.4
6
*
R55, ,
ICD-10 Finland
Syncope and collapse
+∞
6.4
6
*
SCA02, ,
ICD-O-3
+∞
6.4
6
*
H109, ,
ICD-O-3
+∞
6.4
6
*
E7801, ,
ICD-O-3
+∞
6.4
6
*
N06AB10, ,
ATC
escitalopram; oral
+∞
6.4
6
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
6.4
6
*
SPAT1211, ,
ICD-O-3
+∞
6.4
6
*
D07CA01, ,
ATC
hydrocortisone and antibiotics; topical
+∞
6.4
6
*
ULA02, ,
ICD-O-3
+∞
6.4
6
*
AN1, ,
ICD-O-3
+∞
6.4
6
*
SPAT1292, ,
ICD-O-3
+∞
6.4
6
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
6.4
6
*
202, ,
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
6.4
6
*
G560, ,
ICD-10 Finland
Carpal tunnel syndrome
+∞
6.4
6
*
F419, ,
ICD-O-3
+∞
6.4
6
*
NE1AA, ,
ICD-O-3
+∞
6.4
6
*
N10, ,
ICD-10 Finland
Acute tubulo-interstitial nephritis
+∞
6.4
6
*
N02CC01, ,
ATC
sumatriptan; nasal, systemic, rectal
+∞
6.4
6
*
M706, ,
ICD-O-3
+∞
6.4
6
*
R01AD11, ,
ATC
triamcinolone; nasal
+∞
6.4
6
*
J019, ,
ICD-O-3
+∞
6.4
6
*
M545, ,
ICD-10 Finland
Low back pain
+∞
6.4
6
*
NGD05, ,
ICD-O-3
+∞
6.4
6
*
R298, ,
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
+∞
6.4
6
*
J010, ,
ICD-10 Finland
Acute maxillary sinusitis
+∞
6.4
6
*
ND1AA, ,
ICD-O-3
+∞
6.4
6
*
NF1AA, ,
ICD-O-3
+∞
6.4
6
*
MA2AE, ,
ICD-O-3
+∞
6.4
6
*
A23, ,
ICD-O-3
+∞
6.4
6
*
L01, ,
ICD-O-3
+∞
6.4
6
*
E11, ,
ICD-O-3
+∞
6.4
6
*
H903, ,
ICD-10 Finland
Sensorineural hearing loss, bilateral
+∞
6.4
6
*
W17, ,
ICD-10 Finland
Other fall from one level to another
+∞
6.4
6
*
G473, ,
ICD-O-3
+∞
6.4
6
*
D06BX01, ,
ATC
metronidazole; topical
+∞
6.4
6
*
L82, ,
ICD-O-3
+∞
6.4
6
*
M01AH03, ,
ATC
valdecoxib; oral
+∞
6.4
6
*
SPAT1324, ,
ICD-O-3
+∞
6.4
6
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
6.4
6
*
M190, ,
ICD-10 Finland
Primary arthrosis of other joints
+∞
6.4
6
*
H0410, ,
ICD-O-3
+∞
6.4
6
*
U071, ,
ICD-O-3
+∞
6.4
6
*
M179, ,
ICD-O-3
+∞
6.4
6
*
G03DB01, ,
ATC
dydrogesterone; oral
+∞
6.4
6
*
NA1BG, ,
ICD-O-3
+∞
6.4
6
*
C10AX09, ,
ATC
ezetimibe; oral
+∞
6.4
6
*
G03FB06, ,
ATC
medroxyprogesterone and estrogen; systemic
+∞
6.4
6
*
KH1AE, ,
ICD-O-3
+∞
6.4
6
*
DM1QA, ,
ICD-O-3
+∞
6.4
6
*
P01, ,
ICD-O-3
+∞
6.4
6
*
JKA21, ,
ICD-O-3
+∞
6.4
6
*
EBA05, ,
ICD-O-3
+∞
6.4
6
*
M190, ,
ICD-O-3
+∞
6.4
6
*
Z008, ,
ICD-O-3
+∞
6.4
6
*
A10AE04, ,
ATC
insulin glargine; parenteral
+∞
6.4
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
16
53
3.92
4.42
2.4
1.4
—
—
—
0
0
19
85
2.95
3.19
6.5
3.7
—
—
—
0
0
38
259
2.74
2.65
11.8
9.8
4.46
4.05
e9/l
0.43
33
226
23
124
2.53
2.63
5.5
3.0
0.12
0.19
e6/l
0.23
18
88
16
75
2.64
2.39
2.8
2.8
8.64
41.33
ng/l
1.50
11
54
12
50
2.82
2.22
1.6
1.7
—
—
—
0
0
43
336
2.61
2.07
5.0
4.0
12.56
12.11
mm/h
0.10
43
302
21
119
2.28
2.07
11.2
6.2
—
—
—
0
0
31
208
2.21
2.01
9.1
5.1
0.00
0.00
estimate
—
7
44
25
154
2.20
2.01
7.3
4.2
24.24
55.30
e6/l
0.62
19
109
21
122
2.21
1.93
5.9
2.8
—
—
—
0
0
12
54
2.59
1.91
1.3
1.1
—
—
—
0
0
9
35
2.89
1.91
2.8
2.3
6.28
5.66
kpa
—
9
35
9
35
2.89
1.91
1.3
1.5
—
—
—
0
0
31
212
2.14
1.87
6.8
3.6
0.00
0.00
estimate
—
7
46
31
213
2.13
1.84
6.8
3.6
0.00
0.00
estimate
—
7
43
28
186
2.09
1.81
12.8
10.4
1.37
1.24
inr
—
6
68
6
18
3.62
1.80
1.5
2.1
24.47
24.28
mmol/l
—
6
18
7
24
3.20
1.79
2.7
3.0
—
—
—
0
0
29
199
2.03
1.68
8.5
5.3
—
—
—
0
0
47
397
2.91
1.65
24.8
15.8
15.58
14.79
%
0.32
47
389
7
26
2.95
1.64
3.3
2.0
—
—
—
0
0
5
15
3.57
1.56
3.0
1.9
38.90
38.01
g/l
—
5
15
16
90
2.12
1.55
1.3
1.3
26.90
31.44
iu/ml
—
5
37
16
93
2.04
1.42
1.7
1.4
1.35
2.82
g/l
—
5
53
8
34
2.59
1.36
1.6
1.6
—
—
—
0
0
31
230
1.86
1.32
6.3
6.4
10.65
9.41
umol/l
0.45
31
214
14
80
2.03
1.29
2.0
1.9
—
—
—
0
0
6
25
2.58
1.28
3.5
4.0
—
—
—
0
0
46
397
2.37
1.26
6.4
5.0
40.00
39.13
mmol/mol
0.23
46
366
21
140
1.84
1.24
6.3
3.2
16.64
20.56
e6/l
0.20
16
103
6
26
2.47
1.22
3.3
2.3
4.43
4.28
kpa
—
6
26
20
132
1.84
1.21
3.6
2.1
87.20
137.79
u/l
0.81
20
123
5
20
2.65
1.18
2.4
1.7
—
—
—
0
0
24
173
1.72
1.06
2.3
1.8
107.19
100.88
pmol/l
—
9
78
7
36
2.09
1.01
1.4
1.1
—
—
—
0
0
15
96
1.79
0.98
2.0
2.0
—
—
—
0
0
22
160
1.65
0.91
5.4
2.9
—
—
—
0
0
15
98
1.75
0.91
4.5
2.8
5248.00
45.01
mg/l
—
9
58
10
57
1.93
0.91
1.4
1.3
—
—
—
0
0
10
57
1.93
0.91
1.8
2.4
2.60
2.52
g/l
—
10
48
37
311
1.66
0.83
7.2
4.3
—
—
—
0
0
24
182
1.59
0.83
2.0
2.0
—
—
—
0
0
5
23
2.29
0.78
3.0
2.7
1.06
1.21
mmol/l
—
5
23
15
103
1.64
0.76
9.3
3.9
—
—
—
0
0
7
40
1.86
0.75
1.3
1.4
—
—
—
0
0
10
61
1.79
0.75
2.3
2.0
—
—
—
0
0
9
58
1.67
0.75
1.8
1.9
—
—
—
0
0
26
205
1.54
0.74
5.7
5.5
1.21
1.23
mmol/l
0.98
20
171
25
196
1.53
0.73
3.6
2.6
195.81
74.60
ug/l
0.61
25
180
36
306
1.57
0.72
4.9
3.4
—
—
—
0
0
15
105
1.60
0.70
4.6
3.5
3.84
7.18
mg/mmol
—
8
59
13
90
1.59
0.63
1.2
1.3
1.24
11.31
u/ml
—
7
35
5
30
1.74
0.63
1.4
1.3
—
—
—
0
0
6
40
1.56
0.53
4.7
3.7
102.17
102.65
mmol/l
—
6
40
15
112
1.48
0.52
2.7
2.5
303.27
3800.37
umol/l
0.50
15
93
20
160
1.41
0.49
7.8
3.7
13.22
58.44
ng/l
0.99
12
109
8
60
1.39
0.43
1.5
1.7
—
—
—
0
0
5
36
1.43
0.39
7.4
3.5
—
—
—
0
0
6
43
1.45
0.36
1.3
1.2
—
—
—
0
0
14
111
1.36
0.34
9.1
3.9
0.00
0.00
estimate
—
7
44
5
40
1.28
0.23
4.8
4.0
5.32
5.25
kpa
—
5
40
5
40
1.28
0.23
4.8
4.0
9.06
12.88
kpa
—
5
40
15
127
1.25
0.23
4.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
2.9
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
3.8
—
25.42
—
0
13
0
13
0.00
0.21
0.0
2.8
—
8.28
—
0
13
15
129
1.23
0.20
5.7
3.5
—
—
—
0
0
14
154
0.88
0.09
2.6
2.9
—
—
—
0
0
6
56
1.08
0.09
2.3
1.2
—
—
—
0
0
5
59
0.83
0.09
4.6
1.5
54.60
147.85
ug/g
—
5
50
14
133
1.07
0.02
5.4
3.2
—
—
—
0
0
13
137
0.93
0.02
1.3
1.5
—
—
—
0
0
11
108
1.02
0.00
2.0
1.5
12.46
24.02
nmol/l
3.60
11
86
0
7
0.00
0.00
0.0
2.6
—
108.57
—
0
7
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
31.33
—
0
6
0
7
0.00
0.00
0.0
2.6
—
3.91
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
40.68
—
0
5
9
93
0.96
-0.00
2.9
1.6
1484.00
1156.42
nmol/l
—
9
72
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
6.18
—
0
9

Mortality – FinRegistry

Association

Association between endpoint H7_LACRIPAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_LACRIPAS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: H7_LACRIPAS – Other changes in lacrimal passages

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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