Other changes in lacrimal passages

H7_LACRIPAS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H04.6 Hospital discharge: ICD-9 — 3756 Hospital discharge: ICD-8 — 36805 Cause of death: ICD-10 — H04.6 Cause of death: ICD-9 — 3756 Cause of death: ICD-8 — 36805 2 out of 7 registries used, show all original rules.	63
4. Check minimum number of events None	63
5. Include endpoints None	63
6. Filter based on genotype QC (FinnGen only)	55

Control definitions (FinnGen only)

Control exclude: H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H04
Name in latin: Aliae morbositates apparati lacrimalis

NAME	H7_LACRIPAS
CONTROL_EXCLUDE	H7_LIDLACRIMALORBIT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H046
HD_ICD_9	3756
HD_ICD_8	36805
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H046
COD_ICD_9	3756
COD_ICD_8	36805
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other changes in lacrimal passages based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	334	214	120
Only index persons	291	191	100
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	-	54.59	38.23
Only index persons	49.58	54.40	40.38

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	55	47	8
Unadjusted period prevalence (%)	0.01	0.02	0.00
Median age at first event (years)	55.16	58.10	37.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
60: Matched controls
600

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H04.6

ICD-10 Finland

Other changes in lacrimal passages

+∞

63.0

H04.5

ICD-10 Finland

Stenosis and insufficiency of lacrimal passages

271.5

19.8

XCC00

NOMESCO Finland

Investigative irrigation of lacrimal passages

+∞

13.0

H04.10

ICD-10 Finland

Dry eye syndrome

11.0

8.5

3756X

ICD-9 Finland

Disorders of lachrymal system, Other changes of lachrymal passages

+∞

7.4

H04.2

ICD-10 Finland

Epiphora

+∞

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

5.93

2.96

1.3

1.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.93

2.85

2.0

1.3

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.69

2.79

2.9

1.7

2.65

3.28

g/l

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.23

2.56

2.9

1.6

3.16

3.63

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.23

2.56

2.9

1.6

4.20

4.87

g/l

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.23

2.56

2.9

1.6

7.34

7.94

g/l

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

4.51

2.44

2.3

1.8

0.00

g/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.58

2.41

2.5

1.5

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.53

2.18

1.9

1.2

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

3.82

2.13

3.1

1.6

10.60

10.25

g/l

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.12

2.10

1.9

2.3

24.94

24.16

mmol/l

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

3.80

1.89

2.5

1.8

0.00

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

3.80

1.89

2.5

1.8

0.00

g/l

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

3.02

1.87

1.5

1.0

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

106

2.16

1.86

4.9

2.9

1.17

0.67

e6/l

0.45

(3001604) Monocytes [#/volume] in Blood

285

2.05

1.85

9.8

5.1

0.56

0.58

e9/l

0.15

247

(3006315) Basophils [#/volume] in Blood

286

2.04

1.82

9.7

5.1

0.05

0.04

e9/l

1.43

247

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

183

1.99

1.80

4.1

2.7

25.79

26.73

u/l

0.20

173

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

423

2.37

1.79

5.3

4.4

11.82

12.75

mm/h

0.25

385

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.03

1.71

2.0

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

102

2.09

1.68

2.2

1.6

—

(3018095) Leukocytes [#/volume] in Urine

217

1.89

1.58

7.4

4.5

14.59

84.80

e6/l

1.20

157

(3026008) Bacteria identified in Urine by Culture

208

1.88

1.58

4.6

3.1

—

(3030467) Casts [#/volume] in Urine by Automated count

173

1.89

1.54

5.8

3.3

0.11

0.41

e6/l

0.70

124

(40758558) Short blood count panel - Blood

184

1.85

1.47

11.9

5.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

100

1.98

1.42

5.2

2.8

1.67

2.42

e6/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

331

1.90

1.42

13.8

9.8

4.13

4.19

e9/l

0.07

287

(42870588) Differential panel, method unspecified - Blood

177

1.83

1.41

11.4

4.6

—

(40768804) Tissue Pathology biopsy report

224

1.79

1.38

2.0

—

(36304419) Bacteria [Presence] in Urine

161

1.82

1.36

6.0

3.1

—

estimate

—

(3002256) Pathology report gross observation

2.06

1.32

1.5

1.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.34

1.27

3.1

1.8

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

129

1.83

1.27

1.3

26.90

28.23

iu/ml

—

(3009261) Glucose [Presence] in Urine by Test strip

309

1.75

1.20

6.7

4.1

0.00

estimate

—

(3018418) pH of Serum or Plasma

187

1.69

1.12

5.0

3.9

7.41

7.40

0.33

134

(3000991) Gas panel - Venous blood

2.17

1.11

2.6

4.5

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.84

1.10

1.9

2.7

2.51

2.38

g/l

0.40

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

345

1.72

1.08

3.5

2.9

43.52

43.45

u/l

0.00

326

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.92

1.06

1.7

1.6

—

(3000492) Spirometry study

1.98

1.04

1.4

1.7

—

(3035350) Ketones [Presence] in Urine by Test strip

306

1.66

1.04

6.8

4.1

0.00

estimate

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.94

0.94

5.8

6.0

1.19

1.11

mmol/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

131

1.66

0.94

1.9

1.4

2.22

2.66

g/l

—

(3019060) Gas panel - Arterial blood

2.04

0.87

3.5

3.6

—

(36660697) Celiac disease serology panel - Serum

1.85

0.86

1.6

1.1

—

(3015736) pH of Urine

245

1.55

0.86

6.0

3.7

6.26

6.24

0.03

145

(3021601) Nitrite [Presence] in Urine by Test strip

305

1.56

0.85

6.9

4.0

0.00

estimate

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

433

1.72

0.81

5.6

4.9

15.11

14.98

pmol/l

0.13

390

(3003338) MCHC [Entitic Mass/volume] in Red Blood Cells

445

1.74

0.80

33.5

19.4

328.40

330.93

g/l

1.28

445

(3001122) Ferritin [Mass/volume] in Serum or Plasma

268

1.51

0.79

4.1

3.2

173.13

81.08

ug/l

0.60

251

(3002582) Erythrocytes [#/volume] in Urine

201

1.52

0.78

6.6

3.5

14.42

74.02

e6/l

1.10

153

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

340

1.53

0.76

3.5

3.3

—

(3012516) Albumin [Mass/volume] in Urine

165

1.53

0.75

3.9

2.9

25.22

35.05

mg/l

0.24

103

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.68

0.75

1.4

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.80

0.73

2.6

4.4

1.00

1.09

mmol/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.00

0.72

1.2

1.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

214

1.48

0.71

7.1

3.1

—

(3025941) Bacteria identified in Stool by Culture

1.93

0.70

1.4

1.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

114

1.55

0.68

2.3

2.0

—

(3003694) ABO and Rh group [Type] in Blood

181

0.64

0.66

1.3

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.65

0.64

1.8

1.5

—

(3032080) INR in Blood by Coagulation assay

247

1.43

0.63

13.7

12.9

1.19

1.23

inr

0.15

204

(3015235) Bicarbonate [Moles/volume] in Capillary blood

0.00

0.61

0.0

3.5

—

24.89

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

100

1.52

0.58

2.1

1.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

118

1.49

0.58

1.5

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.59

0.58

2.6

1.6

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

183

1.42

0.57

3.5

2.1

110.83

164.38

u/l

0.67

172

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.50

0.55

2.3

1.5

—

(3026493) Urate [Moles/volume] in Serum or Plasma

147

1.43

0.54

2.8

2.6

316.00

332.83

umol/l

0.35

128

(3020682) Albumin/Creatinine [Ratio] in Urine

167

1.40

0.51

4.5

3.7

4.43

5.97

mg/mmol

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

254

1.36

0.50

2.6

2.0

98.06

98.83

pmol/l

0.02

122

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

133

1.39

0.45

1.4

1.7

0.74

0.84

mg/l

0.19

107

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.49

0.42

1.7

1.8

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

487

1.51

0.42

3.8

4.1

1.24

mmol/l

0.00

445

(3025130) Human papilloma virus identified in Specimen

0.00

0.42

0.0

2.3

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.42

0.0

5.5

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.41

0.0

2.9

—

88.96

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.40

0.0

2.8

—

7.92

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.40

0.0

1.7

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.40

0.0

1.3

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

1.47

0.40

4.8

5.1

23.96

25.80

mmol/l

—

(3000494) Fungus identified in Specimen by Culture

1.47

0.40

1.4

1.3

—

(3042936) Bacteria identified in Isolate by Culture

1.44

0.39

2.2

2.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.42

0.39

2.2

1.7

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

301

1.30

0.39

6.9

10.56

9.48

umol/l

0.43

284

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

120

1.33

0.34

1.2

1.3

1.19

12.44

u/ml

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

501

1.50

0.34

6.9

5.9

39.14

38.71

mmol/mol

0.12

469

(40768797) Stomach Pathology biopsy report

1.29

0.27

2.3

1.2

—

(3023368) Bacteria identified in Blood by Culture

153

1.25

0.26

8.6

3.9

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

517

1.44

0.26

4.5

4.8

1.46

1.55

mmol/l

0.89

475

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

510

1.34

0.24

7.2

6.1

1.67

1.87

mu/l

0.75

471

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

292

1.21

0.24

6.1

5.8

1.21

1.22

mmol/l

0.53

249

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.31

0.23

2.4

1.9

—

(3019309) Folate [Moles/volume] in Red Blood Cells

111

0.78

0.22

3.0

1.7

1484.00

1238.07

nmol/l

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

4.6

—

32.43

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(4268621) Lupus anticoagulant assay

0.00

0.21

0.0

1.8

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.21

0.0

1.2

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.31

0.21

1.8

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

176

1.20

0.21

3.5

2.0

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.2

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.21

0.0

1.3

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.20

0.0

3.4

—

31.93

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.0

—

4.50

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.0

—

1.26

—

(3000475) Leukocytes [#/volume] in Synovial fluid

0.00

0.20

0.0

1.3

—

3813.88

—

(3016502) Oxygen saturation in Arterial blood

1.17

0.20

3.5

5.3

95.48

95.64

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.23

0.19

3.7

5.0

5.29

5.12

kpa

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.23

0.19

3.7

5.0

11.90

12.96

kpa

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.17

0.18

9.1

4.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

237

1.17

0.18

7.1

3.9

0.00

estimate

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.22

0.18

1.8

—

(3022145) Colonoscopy Study observation

1.22

0.18

1.6

1.3

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.18

0.17

4.5

4.8

102.00

103.74

mmol/l

—

(1761868) Lipid panel - Serum or Plasma

201

0.85

0.16

2.9

3.2

—

(3029937) Albumin [Presence] in Urine by Test strip

165

1.13

0.10

8.2

4.2

0.00

estimate

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

274

1.11

0.10

2.9

2.5

—

estimate

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

543

0.94

0.09

28.2

17.5

3.99

3.95

mmol/l

0.71

531

(3041096) Erythrocytes [Presence] in Urine by Automated

184

0.89

0.09

5.5

3.4

0.00

estimate

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.80

0.08

19.0

7.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

120

1.11

0.05

3.4

2.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

220

1.07

0.04

7.4

4.1

23.21

50.36

ng/l

0.68

155

(40760892) CBC W Ordered Manual Differential panel - Blood

136

0.94

0.01

4.5

4.6

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.7

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

7.16

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

40.68

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

543

1.15

-0.00

26.3

17.5

139.58

139.71

mmol/l

0.13

532

(3004809) Band form neutrophils/Leukocytes in Blood

0.00

-0.00

0.0

5.3

—

2.29

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.3

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

-0.00

0.0

1.3

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

4.2

—

0.86

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.4

—

0.60

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

1.1

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

-0.00

0.0

1.7

—

11.17

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.6

—

7.11

—

(40761536) Microorganisms panel - Urine sediment

1.00

-0.00

7.8

3.7

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.0

—

246.67

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.93

-0.00

2.2

1.8

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3017732) Neutrophils [#/volume] in Blood

0.99

-0.00

2.1

2.8

3.59

4.47

e9/l

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

-0.00

0.0

1.0

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.2

—

142.13

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.00

-0.00

2.9

2.1

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.4

—

17.42

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.6

—

23.48

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.6

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.3

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

9.3

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.1

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3021788) Differential panel - Synovial fluid

0.00

-0.00

0.0

1.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.4

—

3.91

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.4

—

107.44

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

17.14

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.4

—

1.19

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_LACRIPAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_LACRIPAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_LACRIPAS – Other changes in lacrimal passages

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other changes in lacrimal passages

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints