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Wet age-related macular degeneration, under 50

WET_AMD_EARLY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE<50

Registry filters:

  • Hospital discharge: ICD-10 H35.31
  • Hospital discharge: ICD-9 3625B
  • Cause of death: ICD-10 H35.31
  • Cause of death: ICD-9 3625B

2 out of 7 registries used, show all original rules.

141

4. Check minimum number of events

None

141

5. Include endpoints

None

141

6. Filter based on genotype QC (FinnGen only)

115

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF12
Parent code in ICD-10
H35
Name in latin
Degeneratio maculae senilis exsudativa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 115 59 56
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 42.21 41.12 43.35

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
123
Matched controls
1230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
12476.5
166.2
121
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
124.0
117.9
62
10
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
29.0
76.5
63
43
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
40.8
75.8
51
21
XCK10
NOMESCO Finland
Photography of fundus of eye
28.7
75.5
62
42
XCW99
NOMESCO Finland
Other investigative procedure of eye
23.5
67.9
62
51
CKC12
NOMESCO Finland
Photocoagulation of retina
25.5
50.3
39
22
Z01.0
ICD-10 Finland
Examination of eyes and vision
12.3
44.5
65
103
XCD20
NOMESCO Finland
Photoangiography of eye
77.5
34.7
38
7
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
100.4
34.0
36
5
A10AE05
ATC
insulin detemir; parenteral
13.7
28.0
29
27
A10AC01
ATC
insulin (human); parenteral
11.1
27.5
34
41
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
155.3
24.6
25
*
A10AB01
ATC
insulin (human); parenteral
11.8
24.5
28
30
A10AB05
ATC
insulin aspart; parenteral
9.9
24.2
32
42
Z96.1
ICD-10 Finland
Presence of intraocular lens
11.3
23.0
27
30
CKC10
NOMESCO Finland
Local photocoagulation of retina
54.2
22.4
26
6
A10AA01, ,
ATC
11.1
22.0
26
29
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
10.2
21.4
27
33
H36.01
ICD-10 Finland
Diabetic maculopathy
44.2
20.8
25
7
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
7.4
20.6
36
65
T89
ICPC
Diabetes insulin dependent
10.0
20.4
26
32
XCH00
NOMESCO Finland
Eye pressure measurement
26.1
19.7
27
13
H43.1
ICD-10 Finland
Vitreous haemorrhage
66.3
19.7
22
*
H3603, E103,
ICD-10 Finland
74.1
17.3
19
*
H35.7
ICD-10 Finland
Separation of retinal layers
33.0
17.2
22
8
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
195.4
16.9
17
*
ZXA10
NOMESCO Finland
Bilateral
5.6
16.8
41
101
A10AE04
ATC
insulin glargine; parenteral
6.9
16.1
29
53
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
19.9
15.5
23
14
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
12.4
14.3
26
26
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
13.8
13
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
+∞
13.8
13
*
103
Kela drug reimbursment
Diabetes, insulin-treated
4.3
13.5
49
163
H25.1
ICD-10 Finland
Senile nuclear cataract
6.4
13.4
25
47
A10AA02, ,
ATC
10.9
13.0
25
28
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
11.6
13.0
24
25
H36.00
ICD-10 Finland
Diabetic background retinopathy
36.4
12.9
16
5
215
Kela drug reimbursment
Diabetes, non-insulin-treated
4.1
12.2
47
162
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
11.6
11
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
39.1
11.5
14
*
H35.9
ICD-10 Finland
Retinal disorder, unspecified
48.0
11.2
13
*
H3601, E103,
ICD-10 Finland
24.1
11.0
15
7
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
65.9
10.8
12
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.1
10.5
14
6
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.7
10.3
45
167
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
44.0
10.2
12
*
A11CC03
ATC
alfacalcidol; systemic
44.0
10.2
12
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
28.8
10.0
13
5
A10AB04
ATC
insulin lispro; parenteral
9.7
10.0
20
24
S01ED51
ATC
timolol, combinations; ophthalmic
9.7
10.0
20
24
ZXA05
NOMESCO Finland
Left side
3.8
9.9
40
140
H04AA01
ATC
glucagon; nasal, parenteral
11.5
9.9
18
18
Z49.0
ICD-10 Finland
Preparatory care for dialysis
59.8
9.8
11
*
A10AE06
ATC
insulin degludec; parenteral
9.3
9.8
20
25
S01EC01
ATC
acetazolamide; systemic
19.5
9.7
14
8
XCD10
NOMESCO Finland
Electrophysiological examination of eye
24.0
9.6
13
6
B05DB
ATC
Hypertonic solutions
108.0
9.6
10
*
H3601, E106,
ICD-10 Finland
108.0
9.6
10
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
12.9
9.4
16
14
H3600, E103,
ICD-10 Finland
17.3
9.3
14
9
WX100
NOMESCO Finland
Conjunctival surface anesthesia
9.1
9.3
19
24
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
26.3
9.1
12
5
H26.4
ICD-10 Finland
After-cataract
10.2
8.9
17
19
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
53.9
8.8
10
*
Z3229
NOMESCO Finland
Other healthcare associate professional
5.3
8.7
19
41
Z94.0
ICD-10 Finland
Kidney transplant status
29.9
8.6
11
*
C03CA01
ATC
furosemide; systemic
3.9
8.4
29
90
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
18.8
8.3
12
7
B05DA
ATC
Isotonic solutions
36.0
8.2
10
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
48.1
7.8
9
*
127
Kela drug reimbursment
Transplant complication
19.9
7.8
11
6
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
26.9
7.7
10
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
26.9
7.7
10
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
26.9
7.7
10
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
26.9
7.7
10
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
14.6
7.6
12
9
H3603, E106,
ICD-10 Finland
85.0
7.5
8
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
85.0
7.5
8
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
85.0
7.5
8
*
H35.6
ICD-10 Finland
Retinal haemorrhage
85.0
7.5
8
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
85.0
7.5
8
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
8.2
7.5
16
22
H3603, E113,
ICD-10 Finland
+∞
7.4
7
*
205
Kela drug reimbursment
Chronic hypertension
3.8
7.4
26
82
L04AA06
ATC
mycophenolic acid; systemic
14.9
7.0
11
8
Z49.2
ICD-10 Finland
Other dialysis
42.5
6.8
8
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
42.5
6.8
8
*
B03XA02
ATC
darbepoetin alfa; parenteral
24.1
6.8
9
*
137
Kela drug reimbursment
Uraemia requiring dialysis
24.1
6.8
9
*
C09AA02
ATC
enalapril; systemic
3.9
6.6
21
61
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
15.4
6.5
10
7
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
73.5
6.5
7
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
19.2
6.4
9
5
TK800
NOMESCO Finland
Hemodialysis
19.2
6.4
9
5
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
6.3
6
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
+∞
6.3
6
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
9.4
6.2
12
14
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
9.4
6.2
12
14
S01BC03
ATC
diclofenac; ophthalmic
13.5
6.2
10
8
Z3231
NOMESCO Finland
Registered nurse
2.7
6.1
43
203
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.0
6.1
14
22

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
276
2.99
8.07
9.4
3.5
190.29
49.45
mg/l
1.17
45
192
57
281
2.92
7.74
10.9
4.2
39.97
8.96
mg/mmol
0.80
47
192
32
115
3.41
7.45
22.2
6.5
1.13
1.02
mmol/l
1.39
32
105
60
321
2.70
6.77
9.1
3.3
7.18
9.00
mmol/l
2.07
54
289
6
0
+∞
6.30
5.7
0.0
512.67
—
umol/l
—
6
0
6
0
+∞
6.30
5.5
0.0
18.82
—
mmol/l
—
6
0
13
18
7.93
6.10
3.8
2.8
68.82
65.97
%
0.17
13
18
64
383
2.40
5.37
2.0
1.8
91.56
98.38
pmol/l
0.42
32
203
25
95
3.05
5.21
1.6
1.5
1193.80
1203.79
nmol/l
0.02
20
76
16
48
3.68
4.79
8.6
8.0
20.50
24.86
mmol/l
1.66
16
48
7
5
14.72
4.63
1.6
1.2
—
—
—
0
0
21
77
3.08
4.63
7.4
3.5
1.80
1.89
%
0.17
21
72
28
122
2.68
4.53
3.2
2.7
—
—
—
0
0
14
42
3.63
4.18
1.9
1.4
—
—
—
0
0
22
90
2.76
3.99
14.1
14.7
7.38
7.43
ph
—
10
46
19
73
2.90
3.85
19.8
8.5
—
—
—
0
0
22
92
2.69
3.82
14.1
14.5
4.95
5.16
kpa
0.50
22
85
8
12
7.04
3.73
1.1
1.3
—
—
—
0
0
19
76
2.77
3.58
15.1
16.9
111.63
126.47
g/l
1.52
19
70
6
6
10.42
3.53
1.3
1.0
61.83
115.33
mg/l
—
6
6
11
27
4.37
3.49
1.1
1.2
—
—
—
0
0
9
18
5.30
3.44
3.9
1.4
66.22
65.38
%
—
9
18
17
66
2.83
3.38
6.1
2.2
5.08
4.40
kpa
1.05
17
66
22
98
2.52
3.37
1.5
2.1
407.05
369.78
nmol/l
0.52
22
93
13
43
3.26
3.36
10.6
1.7
22.08
24.94
mmol/l
2.30
13
43
38
216
2.10
3.32
4.1
3.4
—
—
—
0
0
6
7
8.93
3.30
3.2
1.7
10.77
13.34
%
—
6
7
47
291
2.00
3.24
1.4
1.3
4.97
1.15
u/ml
0.45
16
82
13
44
3.19
3.24
15.3
21.8
14.36
16.94
%
1.94
13
38
13
45
3.11
3.13
3.5
2.1
0.57
0.65
%
0.35
13
45
19
82
2.56
3.10
14.4
15.9
96.05
95.82
%
0.06
19
76
12
39
3.30
2.86
1.1
1.4
—
—
—
0
0
54
364
1.86
2.82
13.4
9.0
1.15
1.11
inr
0.23
45
281
23
116
2.21
2.67
2.5
1.7
—
—
—
0
0
10
30
3.53
2.67
3.4
1.3
—
—
—
0
0
13
51
2.73
2.54
16.5
12.5
0.72
0.65
%
0.22
13
51
9
209
0.39
2.36
1.4
1.4
—
—
—
0
0
64
473
1.74
2.34
15.5
10.4
0.00
0.00
e9/l
-0.00
56
379
11
40
2.92
2.34
21.2
3.4
23.37
24.28
mmol/l
0.47
11
40
59
428
1.73
2.30
28.4
8.3
1.21
1.21
mmol/l
0.15
53
376
13
55
2.52
2.20
15.9
11.9
1.34
1.64
%
0.34
13
55
8
25
3.35
2.13
3.5
2.5
24.54
25.77
mmol/l
—
8
25
6
15
4.15
2.06
1.3
1.9
394.83
104.38
ug/l
—
6
15
13
57
2.43
2.06
16.5
11.6
94.96
93.26
%
0.62
13
57
60
448
1.66
2.03
5.9
2.9
6.23
6.15
ph
0.22
37
262
49
347
1.68
2.03
10.0
6.1
—
—
—
0
0
47
330
1.69
2.00
2.7
2.8
24.78
21.43
ng/l
0.16
30
170
67
516
1.66
2.00
6.4
2.9
99.73
100.69
ug/l
0.03
67
495
8
27
3.10
1.97
1.3
1.1
—
—
—
0
0
5
11
4.69
1.96
1.8
1.9
—
—
—
0
0
39
262
1.72
1.95
2.0
1.4
2.49
2.45
g/l
0.04
27
167
45
315
1.68
1.93
10.8
6.4
—
—
—
0
0
6
17
3.65
1.86
2.8
2.9
8.70
8.71
kpa
—
6
17
13
60
2.30
1.85
3.8
3.9
64.95
68.78
g/l
0.66
13
60
7
23
3.16
1.83
10.4
24.6
1.33
1.27
mmol/l
—
7
16
66
515
1.61
1.81
11.1
6.5
2.30
2.77
%
1.45
61
492
67
525
1.61
1.81
11.3
6.5
27.05
28.57
%
0.47
62
510
12
55
2.31
1.74
3.0
1.9
619.43
6961.27
u/l
—
5
21
5
13
3.96
1.73
12.0
1.6
8.74
5.08
pmol/l
—
5
13
18
98
1.98
1.73
2.8
2.5
9.22
10.82
g/l
1.12
18
91
14
69
2.16
1.72
7.2
6.3
0.86
0.50
%
—
7
20
33
219
1.69
1.70
2.3
1.7
1.15
0.68
mg/l
0.61
25
168
32
211
1.70
1.69
5.1
4.7
—
—
—
0
0
46
334
1.60
1.67
11.0
3.6
7.78
93.61
e6/l
0.50
31
220
38
264
1.64
1.65
9.8
4.0
7.39
7.40
ph
0.27
28
181
70
563
1.56
1.63
10.6
6.7
0.59
0.56
e9/l
0.50
63
504
8
32
2.60
1.63
12.4
20.2
0.74
0.90
%
—
8
25
70
564
1.56
1.61
10.5
6.7
0.04
0.04
e9/l
0.05
63
504
72
584
1.56
1.61
11.0
7.0
0.17
0.19
e9/l
0.63
64
527
6
20
3.10
1.60
2.5
2.0
—
—
—
0
0
0
43
0.00
1.55
0.0
7.9
—
—
—
0
0
65
521
1.53
1.49
11.6
6.3
59.29
57.20
%
0.78
60
504
70
571
1.52
1.48
10.9
6.7
2.62
1.93
e9/l
0.36
63
519
5
16
3.21
1.45
1.8
1.2
—
—
—
0
0
27
178
1.66
1.42
9.7
2.7
4.24
3.75
e6/l
0.13
27
161
6
23
2.69
1.38
8.0
2.5
7.37
7.43
ph
—
6
23
19
114
1.79
1.38
16.5
8.1
104.68
104.53
mmol/l
0.05
19
114
11
54
2.14
1.37
1.8
1.9
370.00
305.78
mu/l
0.43
11
49
9
42
2.23
1.37
4.3
2.0
—
—
—
0
0
13
69
1.99
1.34
7.4
6.3
0.17
0.37
%
—
6
19
31
215
1.59
1.34
3.9
2.3
—
—
—
0
0
13
70
1.96
1.29
6.9
6.9
0.00
0.11
%
—
6
18
20
125
1.72
1.27
1.8
1.7
—
—
—
0
0
8
36
2.31
1.27
12.4
18.5
1.21
1.49
%
—
8
29
30
211
1.56
1.22
2.1
1.7
—
—
—
0
0
21
136
1.66
1.18
1.7
1.6
—
—
—
0
0
13
73
1.87
1.16
7.4
6.0
2.83
0.96
%
—
6
23
32
231
1.52
1.16
6.6
2.6
—
—
estimate
—
0
0
66
551
1.43
1.13
6.5
3.1
0.00
0.00
estimate
-0.00
12
100
73
624
1.42
1.08
13.5
11.2
4.55
3.97
e9/l
1.11
66
550
9
47
1.99
1.05
1.7
3.4
18.72
37.13
u/ml
—
9
47
7
34
2.12
1.04
1.1
1.6
0.21
0.25
g/l
—
7
34
5
22
2.32
1.04
1.6
1.6
75.40
54.57
pmol/l
—
5
22
9
48
1.94
1.03
1.1
1.1
—
—
—
0
0
7
35
2.06
1.02
1.1
1.6
1.13
1.22
g/l
—
7
35
23
159
1.55
1.00
3.9
2.7
159.06
93.82
ug/g
0.58
18
127
64
541
1.38
0.97
6.6
3.1
0.00
0.00
estimate
-0.00
12
99
24
169
1.52
0.97
1.7
1.5
186.67
518.95
titre
—
6
38
65
552
1.38
0.96
6.6
3.2
0.00
0.00
estimate
-0.00
12
94
35
269
1.42
0.92
12.0
2.9
12.42
37.00
e6/l
0.67
30
198
40
316
1.39
0.90
3.1
2.1
—
—
—
0
0
31
234
1.43
0.90
9.7
2.7
0.21
0.31
e6/l
0.36
25
161
8
43
1.92
0.89
13.1
16.0
—
—
—
0
0
6
30
2.05
0.88
5.3
1.5
—
—
—
0
0
6
30
2.05
0.88
1.2
1.2
—
—
—
0
0
24
173
1.48
0.87
5.1
3.0
23.47
170.17
ng/l
1.17
17
102
42
339
1.36
0.83
1.6
1.4
—
—
—
0
0
12
74
1.69
0.81
1.0
1.3
132.90
697.85
u/ml
0.81
12
65
77
683
1.34
0.80
9.2
3.6
—
—
—
0
0
33
259
1.37
0.77
2.2
1.7
—
—
—
0
0
21
152
1.46
0.75
8.5
2.4
519.14
573.61
mosm/kgh2o
0.53
21
135
5
24
2.13
0.75
1.0
1.0
—
—
—
0
0
55
470
1.31
0.72
3.3
2.7
—
—
estimate
—
0
0
40
329
1.32
0.69
5.5
2.4
0.00
0.00
estimate
-0.00
11
79
12
78
1.60
0.68
1.3
1.3
—
26.80
—
0
6
118
1202
0.55
0.67
38.5
19.5
40.14
41.78
%
2.49
118
1194
118
1202
0.55
0.67
37.1
19.2
135.48
139.97
g/l
2.30
118
1194
118
1202
0.55
0.67
36.9
19.1
4.55
4.65
e12/l
1.16
118
1186
118
1202
0.55
0.67
36.9
19.3
7.35
6.59
e9/l
0.87
118
1187
118
1202
0.55
0.67
36.6
19.0
29.93
30.26
pg
1.35
118
1195
118
1202
0.55
0.67
36.7
19.1
89.79
90.32
fl
0.65
118
1195
9
138
0.62
0.65
1.1
1.5
—
—
—
0
0
5
29
1.75
0.64
1.6
1.8
9.66
1.04
ug/l
—
5
29
118
1200
0.59
0.62
36.9
19.2
261.57
257.10
e9/l
0.29
118
1187
5
30
1.69
0.62
1.2
1.6
—
—
—
0
0
91
842
1.31
0.61
5.0
4.3
14.52
14.58
pmol/l
0.09
84
806
101
949
1.36
0.60
27.7
15.5
13.62
13.34
%
1.55
101
942
48
415
1.26
0.55
5.5
2.8
0.00
0.00
estimate
-0.00
12
81
6
38
1.61
0.55
1.3
2.1
—
3.07
—
0
15
6
39
1.57
0.54
2.0
1.2
—
—
—
0
0
37
312
1.27
0.52
2.9
2.2
—
—
—
0
0
110
1137
0.69
0.50
16.8
10.6
—
—
—
0
0
22
174
1.32
0.49
2.4
2.0
—
—
—
0
0
112
1077
1.45
0.49
26.3
12.6
22.39
19.57
mg/l
0.41
91
853
7
46
1.55
0.49
5.6
3.9
—
—
—
0
0
115
1113
1.51
0.48
7.3
5.0
2.70
2.91
mmol/l
1.96
110
1074
106
1012
1.34
0.48
6.0
5.0
1.75
1.77
mu/l
0.09
99
968
5
84
0.58
0.47
1.0
1.6
—
—
—
0
0
10
69
1.49
0.46
8.4
3.3
—
—
—
0
0
17
131
1.35
0.45
1.2
1.2
—
—
—
0
0
31
261
1.25
0.44
6.5
3.4
0.00
0.00
estimate
—
10
97
45
396
1.22
0.43
2.0
1.8
—
—
—
0
0
5
32
1.59
0.43
1.0
1.1
—
—
—
0
0
55
494
1.21
0.42
2.3
1.9
1.38
1.45
mmol/l
0.30
47
435
0
19
0.00
0.39
0.0
3.8
—
22.95
—
0
19
0
19
0.00
0.39
0.0
16.6
—
870.89
—
0
19
0
19
0.00
0.39
0.0
20.2
—
1323.00
—
0
19
118
1150
1.64
0.36
30.5
14.6
96.02
73.72
umol/l
1.75
118
1139
107
1033
1.28
0.34
6.6
4.2
6.92
5.79
mmol/l
3.38
102
980
16
128
1.29
0.34
1.5
1.4
—
—
—
0
0
6
46
1.32
0.33
2.0
1.7
—
—
—
0
0
37
333
1.16
0.26
12.0
2.8
53.59
66.58
u/l
0.47
37
308
9
75
1.22
0.25
1.0
1.3
—
—
—
0
0
9
76
1.20
0.25
1.3
1.4
—
262.82
—
0
39
5
38
1.33
0.23
4.2
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
222.42
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
26
290
0.87
0.21
6.8
5.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
67.54
—
0
5
0
14
0.00
0.20
0.0
1.0
—
0.12
—
0
6
12
100
1.22
0.19
1.3
1.1
—
—
—
0
0
10
121
0.81
0.19
1.1
1.2
—
—
—
0
0
6
77
0.77
0.16
1.8
3.2
4.27
4.69
pmol/l
—
6
65
18
202
0.87
0.15
1.3
1.5
—
—
—
0
0
31
288
1.10
0.13
3.4
2.4
—
—
—
0
0
7
66
1.06
0.08
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
1.3
1.1
—
—
—
0
0
7
84
0.82
0.07
2.0
1.2
—
—
—
0
0
24
227
1.07
0.06
1.5
1.3
19.00
21.53
iu/ml
—
6
68
18
190
0.94
0.04
1.2
2.3
1.02
0.75
ug/l
—
6
83
105
1056
0.96
0.00
6.1
4.0
1.31
1.34
mmol/l
0.16
99
1009
56
558
1.01
0.00
3.9
2.9
—
—
—
0
0
21
207
1.02
0.00
1.4
1.3
1.07
5.22
u/ml
—
7
91
14
138
1.02
0.00
2.1
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
6.54
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
34.43
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
178.07
—
0
9
0
5
0.00
-0.00
0.0
2.8
—
3.00
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
94.22
—
0
9
0
9
0.00
-0.00
0.0
1.8
—
1.46
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
7.84
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
22.46
—
0
9
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
0.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
87.95
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
16.93
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: WET_AMD_EARLY – Wet age-related macular degeneration, under 50

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).