Torsion of testis

N14_TORSIOTEST

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only males

244368

2. Check conditions

None

244368

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N44
  • Hospital discharge: ICD-9 6082
  • Hospital discharge: ICD-8 6077
  • Cause of death: ICD-10 N44
  • Cause of death: ICD-9 6082
  • Cause of death: ICD-8 6077

2 out of 7 registries used, show all original rules.

887

4. Check minimum number of events

None

887

5. Include endpoints

None

887

6. Filter based on genotype QC (FinnGen only)

799

Control definitions (FinnGen only)

Control exclude
N14_MALEGEN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N40-N51

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17196 - 17196
Only index persons 15921 - 15921
Unadjusted period prevalence (%)
Whole population 0.48 - 0.48
Only index persons 0.61 - 0.61
Median age at first event (years)
Whole population - - 12.92
Only index persons - - 13.28

-FinnGen-

Key figures

All Female Male
Number of individuals 799 - 799
Unadjusted period prevalence (%) 0.37 - 0.37
Median age at first event (years) 15.34 - 15.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
834
Matched controls
8340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N44
ICD-10 Finland
Torsion of testis
+∞
307.7
602
*
KFH10
NOMESCO Finland
Orchiopexy
155.4
286.0
142
11
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
24.6
240.9
181
93
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
40.7
238.0
148
44
KFA00
NOMESCO Finland
Exploration of testis
504.8
204.8
196
5
60770
ICD-8 Finland
Other disease of male genital organs, Torsion of testis
+∞
158.5
147
*
6082A
ICD-9 Finland
Other disorders of male genital organs, Torsion of testis
+∞
100.0
94
*
KFC00
NOMESCO Finland
Unilateral orchiectomy
17.1
80.4
68
43
ZXD05
NOMESCO Finland
Urgent procedure
4.0
77.5
323
1145
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
19.5
75.7
60
33
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
181.8
65.0
67
*
KFH20
NOMESCO Finland
Detorsion of spermatic cord and fixation of testis
+∞
60.1
57
*
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
15.4
54.0
48
33
KGH10
NOMESCO Finland
Operation for phimosis
165.8
45.3
47
*
ZXE00
NOMESCO Finland
One hour or less
2.4
28.9
290
1530
KFA40
NOMESCO Finland
Incision of scrotum
93.0
24.8
27
*
J01MA02
ATC
ciprofloxacin; systemic
2.3
23.7
238
1240
KFD96
NOMESCO Finland
Other excision or ligature of scrotal organs
+∞
20.9
20
*
N43.3
ICD-10 Finland
Hydrocele, unspecified
26.3
20.5
28
11
XKD00
NOMESCO Finland
Uroflowmetry
3.4
19.8
76
241
N45.0
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis with abscess
107.6
19.6
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
19.4
202
1056
Y02
ICPC
Pain in testis/scrotum
5.1
19.2
41
84
N40
ICD-10 Finland
Hyperplasia of prostate
3.1
18.1
80
276
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
97.2
17.6
19
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
16.6
66
214
N46
ICD-10 Finland
Male infertility
19.7
15.6
23
12
N50.9
ICD-10 Finland
Disorder of male genital organs, unspecified
14.3
15.1
25
18
ZXA00
NOMESCO Finland
Right side
2.2
14.9
152
781
KFA10
NOMESCO Finland
Exploratory incision of testis
+∞
14.6
14
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
14.2
123
591
KED22
NOMESCO Finland
Transurethral resection of prostate
43.3
14.1
17
*
UKC02
NOMESCO Finland
Cystoscopy
2.9
13.1
64
234
R33
ICD-10 Finland
Retention of urine
4.4
13.0
33
78
KFD20
NOMESCO Finland
Excision of hydrocele of testis
50.8
12.9
15
*
60500
ICD-8 Finland
Redundant prepuce and phimosis, Phimosis
+∞
12.5
12
*
N48.1
ICD-10 Finland
Balanoposthitis
3.4
12.3
45
138
Y05
ICPC
Scrotum/testis sympt/compl other
4.6
11.7
28
63
J01EA01
ATC
trimethoprim; systemic
3.3
11.5
43
134
G04CA02
ATC
tamsulosin; oral
2.1
10.8
110
562
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
9.8
244
1649
R10.0
ICD-10 Finland
Acute abdomen
3.9
8.7
25
65
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
14.2
8.7
14
10
KFD16
NOMESCO Finland
Partial excision of epididymis
50.5
8.7
10
*
N49.2
ICD-10 Finland
Inflammatory disorders of scrotum
11.7
8.6
15
13
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.9
8.4
38
133
KFH96
NOMESCO Finland
Other reconstructive operation on testis, epididymis or vas deferens
+∞
8.3
8
*
N43.4
ICD-10 Finland
Spermatocele
6.9
8.1
19
28
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.9
8.0
37
131
ZXA05
NOMESCO Finland
Left side
1.8
7.9
121
711
N41.1
ICD-10 Finland
Chronic prostatitis
3.5
7.6
25
72
UJF32
NOMESCO Finland
Coloscopy
1.8
7.5
119
704
WX704
NOMESCO Finland
Intubation
2.3
7.5
55
246
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.5
198
1348
N48.4
ICD-10 Finland
Impotence of organic origin
3.3
7.4
27
83
R39.1
ICD-10 Finland
Other difficulties with micturition
3.8
7.4
22
59
J01AA02
ATC
doxycycline; systemic
1.5
7.3
440
3574
6050A
ICD-9 Finland
Redundant prepuce and phimosis[PHIMOSIS]
+∞
7.3
7
*
7509
FHL
Other measure in this category
+∞
7.3
7
*
G04CB02
ATC
dutasteride; oral
3.7
7.2
22
60
N02AX02
ATC
tramadol; systemic, rectal
1.6
7.2
235
1679
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
7.2
33
117
WX402
NOMESCO Finland
General anaesthesia
1.7
7.1
154
995
R52.9
ICD-10 Finland
Pain, unspecified
2.0
7.1
73
374
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
7.1
42
170
AA1AD
NOMESCO Finland
CT of head and brain
1.7
6.9
136
856
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
6.8
712
6456
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.8
602
5249
N30.9
ICD-10 Finland
Cystitis, unspecified
4.3
6.8
17
40
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
6.7
54
251
J01MA12
ATC
levofloxacin; systemic
1.9
6.6
80
436
WX702
NOMESCO Finland
Supraglottic ventilation device
2.5
6.5
40
165
G04CA01
ATC
alfuzosin; oral
2.0
6.5
70
365
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
6.4
36
142
G04CB01
ATC
finasteride; oral
2.5
6.4
38
154
KFA96
NOMESCO Finland
Other exploration or incision of scrotum or organs
70.4
6.4
7
*
7513
FHL
Test prosthesis installation
+∞
6.3
6
*
G04CA52
ATC
tamsulosin and dutasteride; systemic
2.8
6.1
29
105
N45
ICD-10 Finland
Orchitis and epididymitis
8.7
6.1
12
14
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
3.2
6.1
23
73

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
396
2648
1.94
19.29
3.9
2.7
8.71
3.18
e6/l
—
7
39
268
1726
1.81
13.50
4.2
3.7
58.82
49.54
e6/l
0.08
191
1203
238
1481
1.85
13.39
3.7
3.1
71.64
90.70
e6/l
0.11
186
1107
426
3314
1.58
9.58
4.2
3.2
—
4.50
—
0
5
201
1298
1.72
9.55
3.5
3.1
0.10
0.33
e6/l
2.80
150
918
158
958
1.80
9.32
3.1
2.7
2.41
2.28
e6/l
0.09
150
882
350
2630
1.57
8.96
3.8
2.7
0.00
0.73
estimate
0.50
66
411
347
2621
1.55
8.58
3.8
2.7
0.00
7.42
estimate
0.79
66
454
724
6504
1.86
8.44
13.9
11.5
25.24
24.56
mg/l
0.20
586
4970
278
2007
1.58
8.33
2.6
2.8
—
—
estimate
—
0
0
514
4253
1.54
8.24
7.9
8.0
77.92
81.63
u/l
1.13
491
4092
343
2604
1.54
8.18
3.8
2.7
0.00
0.00
estimate
-0.00
69
464
692
6151
1.73
8.15
15.6
13.0
3.98
3.98
mmol/l
0.36
676
6000
142
868
1.77
8.09
3.8
2.7
596.18
585.89
mosm/kgh2o
0.15
132
772
92
494
1.97
7.86
3.8
2.1
—
—
—
0
0
299
2221
1.54
7.79
3.3
2.7
6.25
6.16
ph
0.85
171
1290
75
377
2.09
7.68
1.6
1.9
5.20
4.40
u/l
0.80
57
300
686
6113
1.69
7.64
15.7
12.9
139.78
139.80
mmol/l
0.09
671
5980
201
1375
1.61
7.44
2.7
2.3
14.85
14.95
nmol/l
0.07
183
1298
115
697
1.75
6.70
2.8
3.0
2.40
2.42
mmol/l
0.95
103
622
289
2195
1.48
6.52
6.0
6.1
38.38
38.15
g/l
0.30
273
2070
183
1271
1.56
6.25
4.3
2.9
0.00
0.01
estimate
0.69
63
418
190
1333
1.55
6.20
4.7
4.5
—
—
—
0
0
760
7065
1.85
6.10
10.1
9.6
34.39
35.19
u/l
0.32
749
6935
206
1479
1.52
6.03
3.5
3.2
2.37
2.37
mmol/l
0.09
191
1382
273
2081
1.46
5.94
11.4
9.2
1.17
1.15
inr
0.50
228
1730
379
3084
1.42
5.74
6.7
6.1
6.28
6.62
mmol/l
2.86
368
2967
146
990
1.58
5.49
4.6
3.6
366.47
633.39
ng/l
0.69
96
673
120
780
1.63
5.38
3.2
2.8
0.92
0.53
e6/l
0.24
52
363
268
2081
1.42
5.15
3.8
2.4
0.00
0.00
estimate
-0.00
59
412
218
1635
1.45
5.04
1.8
1.8
—
—
—
0
0
87
532
1.71
4.92
1.9
1.9
210.36
228.65
pmol/l
1.32
80
506
415
3496
1.37
4.83
11.0
11.8
3.78
3.95
e9/l
0.89
363
3046
331
2706
1.37
4.57
6.2
7.0
11.73
12.86
umol/l
1.44
317
2593
188
1402
1.44
4.42
2.5
2.6
—
—
—
0
0
53
290
1.88
4.35
11.5
17.4
18.04
16.94
%
1.73
48
277
288
2323
1.37
4.26
2.5
2.6
69.65
67.43
nmol/l
0.69
269
2203
52
287
1.87
4.16
2.0
1.8
315.80
284.25
mu/l
0.21
47
270
486
4269
1.33
3.96
3.5
3.0
15.04
14.81
pmol/l
1.19
454
3949
177
1331
1.42
3.95
3.8
2.7
1.02
1.02
kg/l
1.34
107
752
242
1923
1.36
3.88
2.4
2.2
—
—
—
0
0
151
1107
1.44
3.87
2.3
2.4
1.14
1.11
mg/l
0.04
100
765
51
288
1.82
3.82
2.7
2.7
—
—
—
0
0
54
311
1.79
3.80
3.2
2.4
0.16
0.32
e6/l
0.49
49
296
76
488
1.61
3.60
1.3
1.2
—
—
—
0
0
23
98
2.39
3.60
6.3
11.9
103.83
105.42
mmol/l
0.35
18
85
23
98
2.39
3.60
6.3
11.9
13.00
11.73
mmol/l
0.86
18
85
125
897
1.46
3.58
4.3
5.8
0.84
0.83
mmol/l
0.51
118
863
213
1678
1.36
3.57
3.2
2.9
60.67
61.86
u/l
0.09
203
1592
290
2393
1.32
3.56
8.6
8.9
1.21
1.21
mmol/l
0.51
262
2129
626
5754
1.35
3.48
4.7
4.4
37.09
37.69
mmol/mol
0.94
602
5572
587
5350
1.33
3.42
4.1
3.6
1.76
1.82
mu/l
0.72
550
5049
724
6825
1.46
3.40
11.7
9.2
—
—
—
0
0
113
806
1.46
3.34
2.6
2.2
—
—
—
0
0
188
1467
1.36
3.33
2.6
2.4
374.74
304.21
u/l
0.25
176
1409
178
1382
1.37
3.25
5.6
4.5
7.39
7.39
ph
0.61
128
952
211
1682
1.34
3.25
6.4
7.7
—
—
—
0
0
86
584
1.53
3.22
4.0
6.3
1.67
1.57
mmol/l
0.13
78
516
607
5578
1.32
3.21
3.8
3.5
5.67
5.82
mmol/l
2.88
583
5270
261
2149
1.31
3.20
9.5
8.7
1.20
1.21
mmol/l
1.25
247
2027
791
7621
1.74
3.16
19.7
16.5
4.92
4.90
e12/l
0.45
776
7454
790
7609
1.72
3.15
19.8
16.6
244.49
246.25
e9/l
0.40
779
7444
329
2798
1.29
3.15
11.5
11.1
0.00
0.00
e9/l
0.27
270
2279
16
62
2.61
3.06
1.5
1.6
52.00
74.51
mmol/l
1.03
11
53
791
7630
1.71
3.02
19.7
16.6
6.54
6.51
e9/l
0.15
778
7459
355
3062
1.28
3.01
7.5
8.1
30.27
30.26
%
0.00
339
2969
377
3276
1.28
3.01
8.2
8.7
0.20
0.20
e9/l
0.13
330
2913
200
1600
1.33
2.98
3.6
2.2
0.00
0.10
estimate
0.74
57
379
97
687
1.47
2.98
8.4
10.8
104.47
104.25
mmol/l
0.15
97
687
73
487
1.55
2.98
12.2
13.9
96.74
96.25
%
0.67
68
470
280
2349
1.29
2.94
3.5
3.0
1.62
1.37
ug/l
0.86
260
2144
625
5796
1.31
2.91
17.8
14.6
13.09
13.16
%
1.06
615
5709
161
1254
1.35
2.87
1.9
1.8
—
—
—
0
0
23
109
2.14
2.87
1.7
2.1
1.87
3.06
iu/l
—
10
51
87
608
1.48
2.86
3.8
6.3
7.38
7.37
ph
0.87
51
377
26
130
2.03
2.83
1.2
1.3
202.98
199.97
pmol/l
0.05
26
130
281
2369
1.28
2.82
2.4
2.8
136.36
159.37
ug/l
1.00
264
2270
685
6447
1.35
2.79
4.1
3.9
4.58
4.64
mmol/l
0.80
659
6226
161
1261
1.34
2.76
1.6
1.7
—
—
—
0
0
87
614
1.47
2.73
1.5
1.6
—
—
—
0
0
686
6465
1.34
2.72
4.3
4.2
2.87
2.88
mmol/l
0.11
656
6215
336
2907
1.26
2.70
7.7
8.4
0.70
0.69
%
0.17
315
2803
99
719
1.43
2.68
1.6
1.7
—
—
—
0
0
225
1855
1.29
2.67
2.8
2.8
16.49
136.94
ng/l
0.62
139
1078
69
467
1.52
2.66
12.2
13.9
131.23
130.13
g/l
0.15
64
454
375
3295
1.25
2.61
8.1
8.1
1.88
2.02
e9/l
2.46
335
2937
107
793
1.40
2.59
1.7
1.6
177174316.61
14714722.49
pmol/l
0.44
92
700
335
2914
1.25
2.53
7.6
8.3
3.12
2.98
%
0.52
316
2808
10
31
3.25
2.52
1.2
1.3
—
69.80
%
—
0
5
336
2929
1.25
2.48
7.7
8.4
9.16
9.01
%
0.47
317
2827
82
586
1.44
2.43
2.4
2.1
361.99
356.60
nmol/l
0.09
75
554
77
544
1.46
2.43
11.8
12.9
7.41
7.41
ph
0.08
37
286
35
205
1.74
2.41
1.5
2.0
8.49
6.83
iu/l
0.45
25
155
18
84
2.17
2.36
1.4
2.0
—
—
—
0
0
18
84
2.17
2.36
1.4
2.0
—
—
—
0
0
18
84
2.17
2.36
1.4
2.0
—
—
—
0
0
18
84
2.17
2.36
1.4
2.0
—
—
—
0
0
679
6425
1.31
2.35
4.0
3.9
1.24
1.27
mmol/l
1.67
652
6180
76
541
1.45
2.31
11.8
12.9
5.17
5.14
kpa
0.10
71
519
576
5347
1.25
2.31
3.5
3.4
45.26
47.00
u/l
0.25
561
5178
360
3189
1.23
2.22
8.3
8.1
0.57
0.60
e9/l
1.80
313
2789
75
537
1.44
2.22
12.0
12.9
0.82
0.82
mmol/l
0.00
60
450
43
273
1.61
2.22
2.7
4.9
0.60
0.62
%
0.23
43
273
267
2292
1.24
2.21
3.4
3.8
31.09
36.29
u/l
2.89
256
2180
360
3191
1.23
2.21
8.1
8.1
0.04
0.04
e9/l
0.27
312
2786
342
3017
1.23
2.19
7.6
8.0
54.24
54.86
%
0.47
330
2945
75
541
1.42
2.14
12.0
12.9
12.53
13.28
kpa
0.64
70
522
47
308
1.56
2.13
3.5
5.3
142.64
138.14
g/l
0.48
47
301
641
6048
1.26
2.09
3.5
3.4
1.40
1.39
mmol/l
0.06
616
5803
125
984
1.32
2.08
3.3
3.6
137.51
152.39
ug/g
0.21
102
851
43
278
1.58
2.07
1.8
2.0
0.00
0.00
estimate
-0.00
15
73
83
615
1.39
2.04
1.4
1.3
—
—
—
0
0
131
1044
1.30
2.00
2.2
2.4
2.51
2.70
mg/l
0.57
116
937
101
777
1.34
1.97
8.9
8.7
1.04
1.10
mmol/l
1.00
96
742
23
129
1.81
1.87
2.6
4.4
—
—
—
0
0
162
1341
1.26
1.83
2.8
2.8
374.65
371.30
umol/l
0.16
149
1250
112
887
1.30
1.80
2.2
2.5
—
—
—
0
0
72
536
1.38
1.75
1.1
1.1
—
—
—
0
0
27
163
1.68
1.73
5.7
9.0
0.91
0.91
%
0.00
22
148
15
75
2.02
1.70
2.1
2.3
7.10
5.42
mmol/24h
1.31
15
66
76
577
1.35
1.64
2.5
3.0
35.34
123.74
u/l
0.56
64
505
64
474
1.38
1.62
4.3
5.6
0.56
0.88
%
0.80
16
158
126
1032
1.26
1.57
1.5
1.5
17.24
17.48
nmol/l
0.09
114
916
5
15
3.35
1.52
1.4
1.6
—
—
—
0
0
130
1074
1.25
1.51
2.2
2.7
—
—
—
0
0
17
94
1.83
1.48
1.9
2.3
—
—
—
0
0
69
526
1.34
1.47
1.8
1.6
1151.70
1104.54
nmol/l
0.17
57
422
50
362
1.41
1.46
6.2
3.1
—
—
—
0
0
127
1051
1.25
1.45
2.6
2.5
—
—
—
0
0
12
59
2.05
1.44
5.0
3.7
—
—
—
0
0
183
1578
1.20
1.41
1.4
1.4
0.91
2.04
u/ml
1.59
44
432
15
81
1.87
1.40
3.2
7.7
13.25
11.97
%
0.57
15
81
7
29
2.43
1.39
4.1
2.7
—
—
—
0
0
60
454
1.35
1.36
4.5
5.7
0.00
0.12
%
2.32
12
138
25
160
1.58
1.33
1.4
2.3
71.53
17.94
e6/l
0.38
17
112
8
34
2.37
1.29
1.6
1.6
2250.00
2173.03
ml
—
8
34
133
1122
1.22
1.29
2.5
2.5
—
—
—
0
0
25
162
1.56
1.27
2.4
2.1
—
—
—
0
0
41
295
1.41
1.27
1.3
1.2
—
—
—
0
0
54
408
1.35
1.25
1.4
1.3
—
—
—
0
0
25
163
1.55
1.24
1.4
2.3
4574.95
1233.37
e6/l
0.47
20
119
59
453
1.33
1.23
4.1
5.2
0.46
0.61
%
0.39
13
151
28
188
1.51
1.22
1.2
1.2
—
—
—
0
0
11
56
1.98
1.22
1.0
1.0
—
—
—
0
0
27
180
1.52
1.22
5.7
8.4
1.69
1.75
%
0.14
22
165
56
428
1.33
1.21
3.0
3.8
—
—
—
0
0
132
1122
1.21
1.19
2.6
2.5
—
—
—
0
0
91
744
1.25
1.18
4.3
3.7
—
—
—
0
0
60
466
1.31
1.17
4.9
6.0
0.00
0.08
%
—
9
139
73
584
1.27
1.14
11.6
12.5
—
—
—
0
0
8
40
2.01
1.12
1.1
1.0
—
—
—
0
0
158
1374
1.18
1.12
2.4
2.1
0.64
0.64
ug/l
0.00
74
544
8
41
1.96
1.09
1.1
2.4
32.37
32.95
pg
—
8
41
39
288
1.37
1.07
3.1
3.7
129.97
147.66
ng/l
0.12
30
239
19
121
1.58
1.06
6.3
4.0
2.54
2.30
mmol/l
0.15
14
78
208
1862
1.16
1.03
1.8
1.7
94.84
98.06
pmol/l
0.46
114
1025
86
713
1.23
1.01
3.3
3.5
4.86
8.00
umol/l
3.74
77
640
83
687
1.23
0.99
2.5
2.9
23.85
25.57
%
0.65
78
664
129
1117
1.18
0.97
2.6
2.5
—
—
—
0
0
13
77
1.70
0.95
2.1
1.3
—
—
—
0
0
22
150
1.48
0.93
1.5
2.4
—
—
—
0
0
24
168
1.44
0.90
2.4
3.5
23.63
24.59
mmol/l
1.02
24
168
36
271
1.34
0.90
8.1
9.4
23.45
24.52
mmol/l
0.80
31
256
42
324
1.31
0.90
1.3
1.2
49.65
111.64
u/ml
1.63
15
99
26
186
1.41
0.88
1.2
1.1
1.88
6.24
u/ml
1.90
17
95
127
1109
1.17
0.88
2.4
2.4
—
—
—
0
0
6
30
2.01
0.87
1.2
1.0
—
—
—
0
0
26
187
1.40
0.86
4.2
4.4
195.86
398.46
mg/l
1.21
14
130
67
554
1.23
0.83
1.1
1.2
—
—
—
0
0
180
1621
1.14
0.83
1.3
1.3
—
—
—
0
0
8
46
1.75
0.82
2.0
2.2
22.59
26.07
umol/l
—
8
46
167
1497
1.14
0.82
1.6
1.5
—
—
—
0
0
39
305
1.29
0.78
1.5
1.6
5.92
6.07
ph
0.36
19
172
0
27
0.00
0.77
0.0
1.0
—
—
—
0
0
174
1573
1.13
0.76
5.8
5.0
—
—
—
0
0
18
255
0.70
0.75
1.1
1.1
—
—
—
0
0
144
1287
1.14
0.75
1.3
1.3
—
—
—
0
0
5
24
2.09
0.74
1.6
1.6
190.20
191.29
mmol/24h
—
5
24
18
254
0.70
0.74
1.1
1.1
—
—
—
0
0
149
1336
1.14
0.74
4.5
4.5
4.36
21.76
mg/mmol
0.85
95
955
34
264
1.30
0.72
6.3
7.0
—
—
—
0
0
215
1975
1.12
0.72
3.9
3.8
9.71
9.82
mmol/l
0.09
190
1790
99
863
1.17
0.72
1.7
1.6
—
—
—
0
0
5
28
1.79
0.66
2.6
1.7
—
—
—
0
0
65
554
1.19
0.63
2.9
2.0
0.31
0.29
mg/l
0.09
34
303
90
789
1.16
0.63
2.4
2.2
—
—
—
0
0
17
121
1.41
0.62
1.4
1.5
107.46
296.26
ug/g
—
8
67
23
173
1.34
0.62
1.0
1.1
—
—
—
0
0
26
200
1.31
0.61
1.2
1.1
2.47
2.35
u/ml
0.04
16
112
91
801
1.15
0.60
1.3
1.4
840.00
309.69
titre
0.79
14
128
0
20
0.00
0.60
0.0
3.3
—
—
—
0
0
35
281
1.26
0.60
9.4
10.0
1.24
1.23
mg/l
0.05
35
269
15
105
1.44
0.60
1.4
1.3
10.76
28.86
u/l
0.94
15
95
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
0.00
—
0
22
91
803
1.15
0.59
2.5
2.9
14.44
15.16
umol/l
0.43
85
771
10
64
1.57
0.58
1.2
1.0
—
—
—
0
0
21
158
1.34
0.57
1.6
2.2
0.74
1.64
ug/l
1.07
16
141
43
356
1.22
0.57
1.9
2.1
6.44
10.31
ug/l
1.02
37
322
8
54
1.49
0.57
1.0
1.2
—
—
—
0
0
12
81
1.49
0.57
2.5
2.1
1.72
1.76
mmol/l
0.06
12
81
49
412
1.20
0.56
4.2
5.0
7.40
7.41
ph
0.73
39
346
10
65
1.54
0.55
1.4
1.3
—
—
—
0
0
158
1451
1.11
0.55
1.5
1.6
2.28
2.40
g/l
0.45
101
990
6
39
1.54
0.53
2.2
1.3
84.00
79.15
umol/l
—
6
39
85
757
1.14
0.50
2.5
2.9
2.40
2.36
g/l
0.31
78
723
17
127
1.35
0.50
2.5
2.1
—
—
—
0
0
23
181
1.28
0.48
1.0
1.2
—
—
—
0
0
7
46
1.53
0.48
2.1
4.5
0.57
0.78
index
—
7
46
37
310
1.20
0.46
1.4
1.3
—
—
—
0
0
5
85
0.59
0.45
3.0
3.5
0.80
1.05
%
—
5
78
76
678
1.13
0.45
3.6
3.3
3.80
5.27
e9/l
1.10
65
619
24
296
0.81
0.44
1.0
1.1
—
—
—
0
0
20
157
1.28
0.43
3.1
3.2
4.70
2.26
index
—
10
89
71
795
0.88
0.43
1.5
1.2
23.33
31.15
iu/ml
0.28
20
200
28
337
0.82
0.42
2.4
3.9
7.31
7.34
ph
0.27
21
264
25
204
1.23
0.41
1.8
1.7
109.13
136.39
au/ml
—
8
71
106
971
1.11
0.41
1.4
1.6
3.58
3.65
mmol/l
0.22
74
633
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
3.58
—
0
12
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
44
381
1.16
0.40
1.2
1.2
—
—
—
0
0
10
71
1.41
0.39
1.7
1.5
0.58
0.57
e9/l
—
10
71
58
514
1.14
0.39
2.4
4.3
1.61
1.68
%
0.28
52
481
19
151
1.26
0.38
1.5
1.9
2.44
0.80
g/l
0.56
13
121
5
36
1.39
0.38
14.0
3.9
573.40
1823.00
mg
—
5
36
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
5
37
1.35
0.37
1.6
1.1
—
—
—
0
0
25
207
1.21
0.37
3.1
2.3
—
—
—
0
0
9
70
1.29
0.36
3.7
2.3
—
—
—
0
0
9
71
1.27
0.36
13.9
12.6
0.64
0.59
mmol/l
—
9
62
41
358
1.15
0.35
2.3
4.1
78.25
72.41
e9/l
0.37
25
256
6
46
1.31
0.33
3.0
3.3
992.83
584.63
u/ml
—
6
46
6
90
0.66
0.33
1.5
1.4
—
—
—
0
0
25
213
1.18
0.29
1.8
1.6
—
—
—
0
0
29
251
1.16
0.28
1.2
1.1
0.77
2.86
u/ml
2.55
21
142
8
65
1.23
0.27
1.4
4.6
—
—
—
0
0
22
187
1.18
0.27
1.0
1.2
—
—
—
0
0
14
113
1.24
0.26
3.7
2.3
23.38
27.13
mg/l
—
8
76
79
735
1.08
0.25
1.4
1.6
—
—
—
0
0
11
137
0.80
0.24
1.0
1.2
—
—
—
0
0
9
77
1.17
0.24
3.2
3.1
109.33
136.20
nmol/l
—
9
65
6
83
0.72
0.24
1.7
1.3
—
—
—
0
0
6
84
0.71
0.24
1.7
3.4
—
—
—
0
0
7
94
0.74
0.22
1.3
1.3
—
—
—
0
0
5
40
1.25
0.22
1.6
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
2.89
—
0
10
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
64.00
—
0
12
0
12
0.00
0.21
0.0
1.4
—
324.67
—
0
6
0
12
0.00
0.21
0.0
1.2
—
8.03
—
0
12
5
43
1.16
0.21
3.6
1.6
—
—
—
0
0
5
43
1.16
0.21
2.0
1.2
94.00
106.60
pmol/l
—
5
43
11
89
1.24
0.21
5.8
5.9
9.65
8.81
pmol/l
0.08
11
89
0
13
0.00
0.21
0.0
1.0
—
37.13
—
0
7
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
3.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
20.00
—
0
5
0
14
0.00
0.20
0.0
1.2
—
17.60
—
0
5
0
14
0.00
0.20
0.0
3.4
—
108.64
—
0
14
10
81
1.24
0.19
1.7
1.3
—
—
—
0
0
258
2513
1.04
0.18
1.8
1.8
1.52
1.55
mmol/l
0.19
228
2285
137
1316
1.05
0.18
3.9
3.8
26.31
70.29
mg/l
4.77
94
948
7
62
1.13
0.17
5.4
3.0
—
—
—
0
0
25
224
1.12
0.17
1.2
1.5
—
—
—
0
0
9
78
1.16
0.15
1.3
3.7
32.06
35.51
%
—
9
78
20
178
1.13
0.15
17.1
8.2
—
—
—
0
0
14
121
1.16
0.15
2.8
2.8
48.20
107.66
ug/min
—
7
79
26
284
0.91
0.13
1.3
1.4
106.30
209.87
miu/ml
—
10
113
27
248
1.09
0.13
1.2
1.1
0.79
1.33
u/ml
0.43
19
127
52
492
1.06
0.12
1.6
1.4
—
—
—
0
0
20
181
1.11
0.12
1.2
1.0
0.47
0.68
u/ml
—
9
62
5
45
1.11
0.10
1.2
1.2
5242.00
63133.03
e6/l
—
5
34
5
48
1.04
0.09
1.4
1.1
—
—
—
0
0
30
282
1.07
0.09
1.3
1.1
0.67
2.91
u/ml
2.40
20
157
6
56
1.07
0.08
3.3
3.7
—
108.96
—
0
12
57
548
1.04
0.08
2.4
2.9
0.21
0.23
g/l
1.08
52
507
5
63
0.79
0.08
1.8
4.1
—
—
—
0
0
7
65
1.08
0.08
1.0
1.1
—
—
—
0
0
27
254
1.07
0.08
1.2
1.1
6.89
8.34
u/ml
0.19
18
158
18
166
1.09
0.08
1.2
1.1
—
—
—
0
0
28
264
1.06
0.07
6.2
5.8
3.07
31.10
ug/l
0.56
23
219
8
74
1.08
0.07
1.0
1.1
—
—
—
0
0
29
274
1.06
0.07
5.0
5.5
24.31
24.45
mmol/l
0.18
29
265
8
75
1.07
0.07
1.0
1.5
—
—
nmol/l
—
0
0
8
77
1.04
0.07
7.9
3.5
9.54
32.32
mu/l
—
8
71
7
83
0.84
0.07
1.0
1.1
—
—
—
0
0
9
86
1.05
0.07
1.6
1.5
431.11
329.57
pmol/l
—
9
72
9
86
1.05
0.07
1.9
1.6
50.56
56.93
mu/l
—
9
76
16
148
1.08
0.06
5.8
3.8
54.76
54.75
%
0.00
16
148
29
277
1.05
0.05
1.9
1.4
173.24
206.46
u/ml
0.34
18
164
10
91
1.10
0.04
2.0
1.2
7.40
3.98
u/ml
—
5
47
33
319
1.04
0.03
4.9
5.1
—
—
—
0
0
20
191
1.05
0.03
1.5
1.4
1.92
6.37
iu/ml
—
5
43
34
331
1.03
0.02
1.9
1.3
—
—
—
0
0
39
381
1.02
0.02
2.5
2.2
28.17
15.30
au/ml
—
7
52
129
1279
1.01
0.02
1.7
1.8
4.02
4.01
ratio
0.02
97
942
14
133
1.05
0.01
5.1
6.3
7.29
8.24
%
0.41
14
133
14
133
1.05
0.01
2.6
3.1
33.86
47.34
%
1.32
14
133
19
184
1.03
0.00
1.6
1.9
0.00
0.05
estimate
—
9
60
318
3173
1.00
0.00
2.5
2.5
—
—
—
0
0
11
106
1.04
0.00
2.8
4.3
2.78
3.83
e9/l
3.82
11
106
14
136
1.03
0.00
1.4
1.1
—
—
—
0
0
29
295
0.98
0.00
1.1
1.1
—
—
—
0
0
10
102
0.98
0.00
1.2
1.2
—
—
—
0
0
22
218
1.01
0.00
1.5
1.4
—
—
—
0
0
58
582
1.00
0.00
2.5
2.9
10.62
10.63
g/l
0.01
52
531
71
712
1.00
0.00
1.4
1.2
1.70
7.25
u/ml
2.58
30
318
34
341
1.00
0.00
1.6
1.6
—
—
—
0
0
10
103
0.97
0.00
2.4
2.4
—
57.00
—
0
6
12
117
1.03
0.00
1.8
2.5
145.67
140.01
g/l
0.35
12
93
12
119
1.01
0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
175.38
—
0
8
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
1.84
—
0
9
0
8
0.00
0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.1
2037.00
1470.75
miu/ml
—
5
52
0
7
0.00
-0.00
0.0
5.1
—
512.00
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
7.22
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
21.14
—
0
7
0
7
0.00
-0.00
0.0
5.1
—
15.80
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
114.40
—
0
5
0
6
0.00
-0.00
0.0
2.7
—
0.32
—
0
6
0
5
0.00
-0.00
0.0
2.2
—
13419.40
—
0
5
0
7
0.00
-0.00
0.0
2.9
—
35.86
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.22
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
87.86
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.4
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_TORSIOTEST and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_TORSIOTEST 1.245 [1.01, 1.53] 0.036
Birth year 0.981 [0.97, 0.99] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 209 out of 12271 males with N14_TORSIOTEST died.

Mortality risk

Mortality risk for people of age

years, who have N14_TORSIOTEST.

N-year risk Females Males
1 No data 0.188%
5 No data 1.096%
10 No data 2.86%
15 No data 5.519%
20 No data 9.472%

Relationships between endpoints

Index endpoint: N14_TORSIOTEST – Torsion of testis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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