This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Traumatic amputation of lower leg
ST19_TRAUMAT_AMPUT_LOWER_LEG
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
85 |
4. Check minimum number of eventsNone |
85 |
5. Include endpointsNone |
85 |
6. Filter based on genotype QC (FinnGen only) |
75 |
Control definitions (FinnGen only)
- Control exclude
- ST19_INJURI_KNEE_LOWER_LEG
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- S8
- Name in latin
- Amputatio traumatica genus sive cruris
Similar endpoints
↥List of similar endpoints to
Traumatic amputation of lower leg
based on the number of shared cases.
Similar with more cases:
- Injuries to the knee and lower leg
- Injury, poisoning and certain other consequences of external causes
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 75 | 13 | 62 |
| Unadjusted period prevalence (%) | 0.02 | 0.00 | 0.03 |
| Median age at first event (years) | 53.06 | 52.19 | 53.24 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 77
- Matched controls
- 770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S88.1
ICD-10 Finland
Traumatic amputation at level between knee and ankle
+∞
66.6
54
*
NGQ20
NOMESCO Finland
Amputation of lower leg
148.6
34.1
34
*
X59
ICD-10 Finland
Exposure to unspecified factor
11.7
27.3
43
75
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
59.9
26.4
30
8
NGQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of knee or lower leg
+∞
24.2
22
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
22.7
21.0
31
22
ZXD05
NOMESCO Finland
Urgent procedure
8.6
20.1
50
137
N03AX16
ATC
[U] pregabalin
7.4
17.6
40
98
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
+∞
17.3
16
*
S88.0
ICD-10 Finland
Traumatic amputation at knee level
+∞
16.2
15
*
ZZA00
NOMESCO Finland
Split skin graft
31.4
16.2
21
9
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
8.1
16.2
28
51
S88.9
ICD-10 Finland
Traumatic amputation of lower leg, level unspecified
+∞
15.1
14
*
Z89.5
ICD-10 Finland
Acquired absence of leg at or below knee
+∞
15.1
14
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.7
13.7
29
64
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.6
12.8
26
55
NFQ20
NOMESCO Finland
Amputation of femur
56.2
12.3
14
*
L28
ICPC
Limited function/disability (L)
5.8
11.8
29
73
T87.4
ICD-10 Finland
Infection of amputation stump
140.1
11.8
12
*
T93.6
ICD-10 Finland
Sequelae of crushing injury and traumatic amputation of lower limb
+∞
11.8
11
*
NHQ40
NOMESCO Finland
Amputation of toe
22.0
11.3
16
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
11.0
33
98
ZXA05
NOMESCO Finland
Left side
5.0
10.5
32
96
SPAT1229
SPAT
Assessment of need for aid
10.8
10.4
20
24
WX306
NOMESCO Finland
Lumbar epidural anesthesy
24.0
10.2
14
7
A10AE04
ATC
insulin glargine; parenteral
5.9
10.1
22
49
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
13.3
9.9
17
16
S87.8
ICD-10 Finland
Crushing injury of other and unspecified parts of lower leg
+∞
9.6
9
*
J01FF01
ATC
clindamycin; systemic
4.4
9.5
38
139
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
6.1
9.4
19
39
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
56.7
8.9
10
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.5
8.9
30
96
NG4AA
NOMESCO Finland
Lower leg X-ray examination
23.3
8.8
12
6
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
8.3
8.6
19
29
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
9.6
8.4
17
22
H3603, E103,
ICD-10 Finland
50.3
7.9
9
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.4
7.8
17
25
A46
ICD-10 Finland
Erysipelas
4.2
7.8
27
87
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
15.5
7.7
12
9
L89
ICD-10 Finland
Decubitus ulcer and pressure area
15.5
7.7
12
9
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
88.2
7.6
8
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.6
7.5
22
62
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
+∞
7.4
7
*
G54.6
ICD-10 Finland
Phantom limb syndrome with pain
+∞
7.4
7
*
WX702
NOMESCO Finland
Supraglottic ventilation device
11.8
7.4
13
13
AA1AD
NOMESCO Finland
CT of head and brain
3.7
7.4
37
154
CKC12
NOMESCO Finland
Photocoagulation of retina
9.8
7.2
14
17
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
7.0
20
55
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
44.1
6.9
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.7
6.8
31
120
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
8.7
6.8
14
19
X58
ICD-10 Finland
Exposure to other specified factors
4.7
6.7
18
47
WX320
NOMESCO Finland
Spinalanesthesy
3.8
6.6
26
91
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.2
6.6
21
63
WX400
NOMESCO Finland
Inhalation anesthesy
10.7
6.6
12
13
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.3
6.5
20
58
ZX198
NOMESCO Finland
Other local administration
29.3
6.4
8
*
S78.1
ICD-10 Finland
Traumatic amputation at level between hip and knee
+∞
6.3
6
*
S82.2
ICD-10 Finland
Fracture of shaft of tibia
+∞
6.3
6
*
A28
ICPC
Limited function/disability NOS
3.9
6.2
22
71
TPH04
NOMESCO Finland
Cathetrisation of vein
3.6
6.2
27
101
S97
ICPC
Chronic ulcer skin
6.6
6.1
15
27
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
8
8
10.98
4.63
1.4
1.5
—
—
—
0
0
27
126
2.76
4.04
2.3
2.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
11
25
4.95
3.79
2.4
2.0
0.23
0.31
iu/ml
—
5
12
9
20
4.95
3.22
1.7
1.6
—
—
—
0
0
44
282
2.31
3.18
5.2
2.9
—
—
estimate
—
0
0
45
300
2.20
2.86
15.0
7.0
1.21
1.21
mmol/l
0.05
38
280
14
55
2.89
2.80
2.3
1.6
—
—
—
0
0
47
322
2.18
2.75
23.3
9.1
1.21
1.20
mmol/l
0.26
40
289
20
97
2.43
2.67
2.4
1.7
—
—
—
0
0
8
23
3.76
2.34
1.5
1.3
—
—
—
0
0
19
96
2.30
2.30
2.5
1.8
—
—
—
0
0
5
9
5.85
2.25
1.0
1.0
1.14
1.04
nmol/l
—
5
9
55
646
0.48
2.03
6.0
5.4
1.27
1.34
mmol/l
0.94
48
586
53
630
0.49
2.03
4.8
4.6
1.65
1.35
mmol/l
1.66
47
568
15
72
2.35
2.02
6.3
3.0
—
—
—
0
0
25
149
2.00
1.99
5.0
3.8
1.02
1.02
kg/l
0.37
20
98
25
153
1.94
1.83
3.7
2.6
—
—
—
0
0
56
646
0.51
1.69
6.0
5.5
4.45
4.48
mmol/l
0.08
48
589
0
45
0.00
1.56
0.0
2.1
—
3.92
—
0
33
58
656
0.53
1.45
6.4
6.3
2.62
2.65
mmol/l
0.07
51
601
6
23
2.74
1.39
3.5
3.2
—
—
—
0
0
9
42
2.29
1.39
2.2
1.8
—
—
—
0
0
48
382
1.68
1.35
16.9
11.9
5.49
4.11
e9/l
1.80
43
335
34
249
1.65
1.31
4.0
3.4
—
—
—
0
0
8
39
2.17
1.19
1.6
1.3
—
—
—
0
0
5
22
2.36
1.05
1.4
2.6
—
—
—
0
0
18
118
1.69
1.02
1.7
1.5
1111.64
1213.55
nmol/l
0.24
11
91
42
338
1.53
1.02
4.7
3.9
0.00
0.00
estimate
—
8
83
42
343
1.49
0.93
4.7
3.9
0.50
0.00
estimate
—
8
74
6
29
2.16
0.91
2.2
2.2
32.67
2249.17
u/ml
—
6
24
57
630
0.63
0.89
6.6
5.3
6.58
6.11
mmol/l
1.43
51
579
20
141
1.57
0.86
1.8
1.8
0.90
1.79
mg/l
1.62
15
119
24
180
1.48
0.78
1.9
1.8
16.76
17.30
nmol/l
0.10
19
144
28
217
1.46
0.77
9.2
3.7
2.27
2.34
mmol/l
1.05
21
200
10
60
1.77
0.76
19.9
8.1
2.24
1.43
mmol/l
—
10
60
40
336
1.40
0.70
4.9
3.8
0.00
0.00
estimate
—
8
82
7
111
0.59
0.64
2.9
2.5
11.29
14.78
nmol/l
—
7
103
52
463
1.38
0.60
5.2
3.7
94.60
55.43
u/l
0.91
47
435
6
39
1.58
0.54
2.0
4.4
22.97
24.23
mmol/l
—
6
39
67
631
1.48
0.47
44.9
17.7
29.63
25.72
mg/l
0.54
62
530
0
18
0.00
0.40
0.0
1.7
—
5.17
—
0
13
10
131
0.73
0.34
1.3
1.4
—
0.81
—
0
39
15
120
1.31
0.33
15.1
6.6
104.20
104.33
mmol/l
0.02
15
120
50
534
0.82
0.30
59.0
22.0
14.47
13.64
%
2.56
50
528
32
352
0.84
0.25
2.8
2.7
—
—
—
0
0
21
240
0.83
0.25
2.4
3.2
2.68
0.77
ug/l
0.54
16
161
0
10
0.00
0.21
0.0
2.9
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
61
633
0.83
0.21
9.2
6.8
45.26
40.24
mmol/mol
2.07
56
591
22
195
1.18
0.20
5.0
3.7
0.00
0.01
estimate
—
7
68
31
284
1.15
0.19
1.9
2.0
95.40
94.54
pmol/l
0.05
15
144
21
187
1.17
0.18
4.9
3.3
0.00
0.02
estimate
—
7
67
27
251
1.12
0.12
4.4
4.4
95.30
11.75
mg/mmol
1.10
16
168
28
262
1.11
0.11
5.8
3.8
0.00
0.00
estimate
—
8
68
5
45
1.12
0.10
3.8
1.8
—
—
—
0
0
33
318
1.07
0.05
3.7
4.2
21.55
23.55
%
0.33
16
157
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
8
80
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
31.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
82
0.97
-0.00
10.0
9.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ST19_TRAUMAT_AMPUT_LOWER_LEG – Traumatic amputation of lower leg
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).