No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1439 |
4. Check minimum number of eventsNone |
1439 |
5. Include endpointsNone |
1439 |
6. Filter based on genotype QC (FinnGen only) |
1308 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H18
- Name in latin
- Dystrophia corneae hereditaria
Similar endpoints
↥List of similar endpoints to
Hereditary corneal dystrophies
based on the number of shared cases.
Similar with more cases:
- Other disorders of cornea
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6239 | 4234 | 1985 |
| Only index persons | 5832 | 3982 | 1850 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.12 | 0.06 |
| Only index persons | 0.12 | 0.15 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 66.92 | 68.44 | 63.65 |
| Only index persons | 66.40 | 67.91 | 63.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1308 | 896 | 412 |
| Unadjusted period prevalence (%) | 0.28 | 0.32 | 0.19 |
| Median age at first event (years) | 67.18 | 66.35 | 68.97 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1350
- Matched controls
- 13500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CG2T4
NOMESCO Finland
Topography assessment of cornea
291.4
307.7
296
13
TCG10
NOMESCO Finland
Removal of sutures from cornea
153.3
307.7
162
12
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
4503599627370496.0
307.7
1341
5
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
233.5
307.7
248
13
Z94.7
ICD-10 Finland
Corneal transplant status
3260.5
295.9
275
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.0
271.1
604
1398
H16.0
ICD-10 Finland
Corneal ulcer
23.7
237.7
176
85
WX100
NOMESCO Finland
Conjunctival surface anesthesia
6.2
225.0
538
1302
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
222.2
207
*
H18.4
ICD-10 Finland
Corneal degeneration
558.8
199.1
193
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.2
186.4
396
844
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
5.1
162.0
1007
4932
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.5
157.1
856
3776
CG2S4
NOMESCO Finland
Photography of cornea
352.6
156.3
155
5
WX140
NOMESCO Finland
Parabulbar anesthesy
7.9
146.1
221
328
H18.8
ICD-10 Finland
Other specified disorders of cornea
613.7
115.8
113
*
H25.1
ICD-10 Finland
Senile nuclear cataract
3.4
105.7
691
3194
H18.6
ICD-10 Finland
Keratoconus
+∞
93.9
89
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
950.6
91.9
89
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.1
89.2
291
845
H26.4
ICD-10 Finland
After-cataract
3.7
81.3
313
1015
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.0
80.2
269
793
H16.9
ICD-10 Finland
Keratitis, unspecified
106.2
73.8
80
8
H18.1
ICD-10 Finland
Bullous keratopathy
736.0
71.8
70
*
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
371.2
71.3
71
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
102.0
70.7
77
8
XCK10
NOMESCO Finland
Photography of fundus of eye
3.8
70.1
246
744
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
+∞
69.4
66
*
ZXA10
NOMESCO Finland
Bilateral
3.0
68.4
408
1708
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
12.3
65.6
66
56
H04.10
ICD-10 Finland
Dry eye syndrome
3.3
62.9
277
967
WX002
NOMESCO Finland
Sedation and analgesia
2.8
62.0
419
1862
CGG35
NOMESCO Finland
Transplantation of endothelium of cornea
+∞
62.0
59
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
86.8
59.5
66
8
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
581.8
57.1
56
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.3
50.1
616
3557
Z3229
NOMESCO Finland
Other healthcare associate professional
3.4
49.3
195
631
H18.2
ICD-10 Finland
Other corneal oedema
+∞
49.3
47
*
S01ED01
ATC
timolol; ophthalmic
5.3
48.4
101
202
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
108.1
48.1
52
5
S01AD03
ATC
aciclovir; ophthalmic
5.9
46.6
87
157
E85.80
ICD-10 Finland
Meretoja sick
+∞
46.1
44
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.4
45.2
180
584
CGE10
NOMESCO Finland
Keratectomy
+∞
45.0
43
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
13.6
43.5
41
31
CGG30
NOMESCO Finland
Anterior lamellar transplantation of cornea
+∞
39.8
38
*
H52.2
ICD-10 Finland
Astigmatism
7.0
39.3
61
91
H18.3
ICD-10 Finland
Changes in corneal membranes
398.6
39.3
39
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
37.7
36
*
S01EA03
ATC
apraclonidine; ophthalmic
10.8
37.7
41
39
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
9.5
37.6
45
49
H17.8
ICD-10 Finland
Other corneal scars and opacities
345.6
34.1
34
*
CD2S4
NOMESCO Finland
Photography of eye
12.5
33.3
33
27
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
+∞
32.4
31
*
S01XA18
ATC
ciclosporin; ophthalmic
10.0
32.2
37
38
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.0
30.8
143
505
H25.8
ICD-10 Finland
Other senile cataract
2.4
30.0
235
1082
S01ED51
ATC
timolol, combinations; ophthalmic
2.8
29.5
162
627
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
29.3
28
*
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
+∞
29.3
28
*
ZXA05
NOMESCO Finland
Left side
2.0
28.7
422
2492
CGE16
NOMESCO Finland
Destruction of lesion of cornea
+∞
28.2
27
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
28.1
308
1628
Z3231
NOMESCO Finland
Registered nurse
2.0
28.0
433
2598
CHC05
NOMESCO Finland
Iridotomy
6.1
27.9
49
83
ZXA00
NOMESCO Finland
Right side
2.0
27.3
443
2698
ZXE00
NOMESCO Finland
One hour or less
1.8
25.8
574
3857
S01EA05
ATC
brimonidine; ophthalmic
4.6
25.4
62
141
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
25.1
24
*
CGD99
NOMESCO Finland
Other operation for error of refraction
132.5
24.7
26
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
21.2
556
3858
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
20.9
20
*
S01BA04
ATC
prednisolone; ophthalmic
5.0
20.2
44
91
CKD60
NOMESCO Finland
Anterior vitrectomy
6.9
18.7
29
43
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
7.8
18.7
26
34
Z2221
NOMESCO Finland
Medical doctor
1.7
17.9
394
2577
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
17.1
517
3671
H57.1
ICD-10 Finland
Ocular pain
3.4
17.1
63
193
S01AA01
ATC
chloramphenicol; ophthalmic
2.9
16.9
84
307
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
16.8
90
342
CGF10
NOMESCO Finland
Suture of laceration of cornea
64.2
16.8
19
*
XCK00
NOMESCO Finland
Perimetry
2.5
16.2
107
452
S01EC01
ATC
acetazolamide; systemic
4.3
16.0
41
97
H18.7
ICD-10 Finland
Other corneal deformities
+∞
15.7
15
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
15.0
126
592
3715A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Hereditary corneal dystrophies
+∞
14.6
14
*
H02.1
ICD-10 Finland
Ectropion of eyelid
5.6
14.3
27
49
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
14.0
194
1096
S01EE05
ATC
tafluprost; ophthalmic
2.7
13.9
73
275
3604
FHL
Penetration of the cornea
+∞
13.6
13
*
37102
ICD-8 Finland
Corneal opacity, Dystrophia corneae hereditaria
+∞
13.6
13
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
141.4
13.5
14
*
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
13.2
137
699
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.3
13.0
99
446
H16.8
ICD-10 Finland
Other keratitis
50.5
12.9
15
*
S01EE01
ATC
latanoprost; ophthalmic
2.2
12.8
112
534
H26.2
ICD-10 Finland
Complicated cataract
4.8
12.6
28
59
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.7
12.6
29
63
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
12.5
12
*
ZXD20
NOMESCO Finland
Day surgery
1.8
12.4
186
1074
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
12.2
265
1706
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
4.1
11.7
32
80
H16.2
ICD-10 Finland
Keratoconjunctivitis
65.5
11.6
13
*
S01BA01
ATC
dexamethasone; ophthalmic
2.9
11.5
54
192
S01XA03
ATC
sodium chloride, hypertonic; ophthalmic
+∞
11.5
11
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
11.5
11
*
S01ED02
ATC
betaxolol; ophthalmic
4.9
11.5
25
52
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
121.0
11.4
12
*
S01FA01
ATC
atropine; ophthalmic
15.2
11.3
18
12
S01BA07
ATC
fluorometholone; ophthalmic
4.4
11.3
28
65
H26.02
ICD-10 Finland
Presenil cataract
3.0
11.2
48
162
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.5
10.8
66
269
S01BC03
ATC
diclofenac; ophthalmic
3.3
10.6
40
125
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
5.1
10.5
22
44
S01AX11
ATC
[U] ofloxacin
2.7
10.5
56
213
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
110.9
10.4
11
*
H19.8
ICD-10 Finland
Other disorders of sclera and cornea in diseases classified elsewhere
+∞
10.4
10
*
CGG11
NOMESCO Finland
Corneal cross-linking
+∞
10.4
10
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
32.8
10.3
13
*
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
3.8
10.1
30
80
S01KA02
ATC
hypromellose; ophthalmic
3.2
9.7
38
122
E0000UV, ,
ATC
1.4
9.6
542
4271
114
Kela drug reimbursment
Glaucoma
1.8
9.6
137
778
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
15.1
9.5
15
10
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
9.4
9
*
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
9.4
9
*
H18.0
ICD-10 Finland
Corneal pigmentations and deposits
+∞
9.4
9
*
F99
ICPC
Eye/adnexa disease other
5.2
9.4
19
37
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.9
9.2
26
67
CFD10
NOMESCO Finland
Repair of conjunctiva
24.2
8.9
12
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
8.5
521
4142
F29
ICPC
Eye symptom/complaint other
1.7
8.5
147
883
A98
ICPC
Health maint/preventive medicine
2.3
8.5
1295
12311
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
20.2
8.5
12
6
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
90.6
8.4
9
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.6
8.4
46
178
S01EE04
ATC
travoprost; ophthalmic
3.0
8.4
36
122
QAJ30
NOMESCO Finland
Other facelift
12.8
8.4
14
11
CGG20
NOMESCO Finland
Epikeratofakia or keratofakia
+∞
8.3
8
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
8.3
8
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.0
8.2
85
434
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.9
8.0
98
529
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.9
910
8019
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.1
7.9
76
377
QAJ10
NOMESCO Finland
Browlift
13.1
7.9
13
10
H27.0
ICD-10 Finland
Aphakia
13.1
7.9
13
10
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
7.8
7.9
17
22
S01BC05
ATC
ketorolac; ophthalmic
2.3
7.8
58
259
S01EC04
ATC
brinzolamide; ophthalmic
2.2
7.8
65
305
H15.1
ICD-10 Finland
Episcleritis
9.5
7.8
15
16
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
9.5
7.8
15
16
F01
ICPC
Eye pain
2.8
7.7
38
139
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.4
7.7
19
44
H52.1
ICD-10 Finland
Myopia
2.5
7.6
45
181
D07AA02
ATC
hydrocortisone; topical
1.6
7.4
162
1039
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
7.3
7
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
7.3
7
*
CGW99
NOMESCO Finland
Other operation on cornea or sclera
+∞
7.3
7
*
H21.0
ICD-10 Finland
Hyphaema
+∞
7.3
7
*
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
6.6
7.1
17
26
H02.2
ICD-10 Finland
Lagophthalmos
8.0
7.1
15
19
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.0
6.9
19
48
J05AB11
ATC
valaciclovir; oral
1.6
6.9
189
1277
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
13.8
6.9
11
8
QAJ15
NOMESCO Finland
Browlift using video-endoscope
40.3
6.8
8
*
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.0
6.7
29
99
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.7
385
3004
R06AX13
ATC
loratadine; oral
1.6
6.6
176
1182
S01EC03
ATC
dorzolamide; ophthalmic
3.5
6.6
22
64
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.2
6.5
52
240
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
70.2
6.4
7
*
E85.8
ICD-10 Finland
Other amyloidosis
70.2
6.4
7
*
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.3
6.4
44
191
Z01.2
ICD-10 Finland
Dental examination
1.3
6.4
561
4673
H20.8
ICD-10 Finland
Other iridocyclitis
+∞
6.3
6
*
N08.4*E85.80
ICD-10 Finland
Glomerular disease in Meretoja's patients
+∞
6.3
6
*
H54.5
ICD-10 Finland
Severe visual impairment, monocular
7.1
6.2
14
20
XCH05
NOMESCO Finland
Eye pressure longterm registration
3.7
6.2
19
52
D22
ICD-10 Finland
Melanocytic naevi
2.0
6.1
60
301
H02.3
ICD-10 Finland
Blepharochalasis
1.7
6.1
98
578
CBF99
NOMESCO Finland
Other operation for ectropion
12.6
6.1
10
8
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
12.6
6.1
10
8
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
6.1
156
1039
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.0
351
2738
H53.0
ICD-10 Finland
Amblyopia ex anopsia
5.2
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
100
6.45
37.08
1.3
1.3
—
—
—
0
0
37
58
6.53
22.71
1.2
1.2
—
—
—
0
0
741
5981
1.53
12.94
2.6
2.5
81.04
79.51
nmol/l
0.74
640
5322
1213
11051
1.96
12.69
6.5
5.9
1.94
1.96
mu/l
0.22
1105
10111
1292
12084
2.61
12.24
22.5
21.1
139.84
139.65
mmol/l
1.81
1258
11855
1293
12101
2.62
12.18
22.8
21.2
3.98
3.98
mmol/l
0.05
1257
11846
756
6182
1.51
12.03
6.4
6.5
1.22
1.21
mmol/l
1.48
682
5687
1310
12375
2.98
11.42
25.1
23.4
77.43
76.89
umol/l
0.22
1285
12228
1232
11355
1.97
11.37
19.0
17.3
77.25
76.76
ml/min/173m2
0.39
1144
10585
1041
9193
1.58
10.96
4.9
4.6
12.92
13.37
mm/h
0.45
937
8548
1251
11620
2.04
10.84
18.2
17.4
24.18
24.93
mg/l
0.31
1035
9652
1300
12266
2.62
10.76
14.0
13.1
23.61
24.71
u/l
1.98
1251
11895
1264
11790
2.13
10.74
6.7
6.3
2.63
2.67
mmol/l
0.99
1148
10836
1246
11595
1.97
10.16
5.8
5.4
4.61
4.64
mmol/l
0.48
1137
10695
1316
12530
3.00
9.96
28.7
26.7
91.72
91.52
fl
0.89
1299
12391
1316
12530
3.00
9.96
28.9
26.8
246.87
250.76
e9/l
1.40
1276
12274
1316
12532
2.99
9.92
28.9
26.8
6.63
6.70
e9/l
0.44
1273
12228
1316
12532
2.99
9.92
29.4
27.2
43.11
39.76
%
0.50
1298
12388
1316
12532
2.99
9.92
28.8
26.7
4.41
4.41
e12/l
0.16
1272
12227
1057
9436
1.55
9.90
5.2
4.7
14.92
14.97
pmol/l
0.26
952
8611
1316
12534
2.98
9.88
29.0
26.9
132.76
132.98
g/l
0.23
1299
12397
806
6861
1.43
9.24
7.4
7.2
1.22
1.22
mmol/l
1.23
667
5925
1213
11255
1.77
9.11
7.4
6.9
39.71
39.60
mmol/mol
0.18
1107
10453
1235
11525
1.84
9.02
5.8
5.4
1.51
1.51
mmol/l
0.18
1116
10566
717
6029
1.40
8.49
2.3
2.2
101.86
96.39
pmol/l
1.64
358
3038
1228
11484
1.77
8.29
6.1
5.6
6.01
5.98
mmol/l
0.33
1102
10425
1187
11045
1.62
7.62
4.8
4.5
1.26
1.28
mmol/l
0.29
1058
10008
664
5637
1.35
6.79
3.5
3.1
111.74
130.67
ug/l
1.98
606
5203
414
3295
1.37
6.32
3.7
4.1
87.50
89.58
%
1.01
403
3229
282
2104
1.43
6.29
2.7
2.5
2.32
2.31
g/l
0.14
257
1950
927
8331
1.36
6.24
5.3
5.2
461.57
2852.29
e6/l
—
7
124
263
1956
1.43
5.94
2.7
2.6
22.99
22.36
%
0.29
239
1827
86
494
1.79
5.86
2.4
2.0
37.26
39.77
u/l
0.74
77
429
278
2113
1.40
5.52
2.9
3.1
4.26
2.76
e6/l
0.96
144
1063
299
2310
1.38
5.37
2.8
3.0
0.71
1.19
e6/l
2.94
162
1266
1041
9631
1.35
5.09
8.7
8.6
77.44
80.30
u/l
1.66
971
9123
609
5244
1.29
5.09
2.0
2.0
1.29
1.33
mmol/l
0.67
493
4351
290
2258
1.36
4.93
2.8
2.6
13.34
12.71
umol/l
0.74
268
2104
202
1484
1.42
4.84
2.5
2.2
124.83
126.82
ug/g
0.05
157
1188
219
1651
1.39
4.52
6.0
5.4
33.37
32.93
%
0.22
145
1038
681
6012
1.27
4.45
5.0
5.0
35.70
35.37
g/l
0.89
623
5645
511
4360
1.28
4.41
3.3
3.2
1616.47
1264.22
ng/l
0.73
425
3761
185
1365
1.41
4.33
3.9
3.5
—
—
—
0
0
478
4061
1.27
4.23
1.8
1.7
21.80
20.81
nmol/l
0.69
389
3376
740
6636
1.25
4.08
4.3
4.3
11.03
3.45
estimate
0.30
157
1423
64
383
1.70
3.87
1.4
1.3
18.16
6.36
u/ml
—
8
64
434
3683
1.26
3.80
3.3
3.4
0.51
0.44
e6/l
0.14
313
2732
63
381
1.69
3.68
1.3
1.2
38.38
2.61
u/ml
—
5
37
825
7538
1.24
3.66
5.1
5.1
6.62
6.72
mmol/l
0.89
787
7192
413
3502
1.26
3.61
2.6
2.3
2.83
2.91
mg/l
0.26
354
2989
740
6702
1.23
3.49
4.4
4.3
0.00
0.23
estimate
0.54
147
1353
835
7665
1.23
3.44
3.5
3.4
41.16
51.00
u/l
4.50
771
7142
529
4634
1.23
3.41
3.7
3.4
6.82
7.01
mmol/l
0.47
436
3879
330
2759
1.26
3.21
1.7
1.8
1.48
1.40
mg/l
0.13
251
2154
382
3249
1.25
3.19
2.7
2.8
342.55
342.39
umol/l
0.01
322
2822
547
4833
1.22
3.19
3.6
3.7
2.37
2.36
mmol/l
0.82
478
4362
113
809
1.43
3.16
2.2
2.5
13.50
19.58
au/ml
—
9
69
722
6561
1.22
3.16
4.3
4.2
0.00
0.00
estimate
0.50
150
1391
521
4584
1.22
3.16
4.4
4.2
7.57
8.33
mg/mmol
0.18
295
2754
788
7226
1.22
3.13
9.4
9.7
3.97
4.09
e9/l
0.88
661
6270
333
2801
1.25
3.06
1.3
1.3
1.34
1.47
u/ml
0.08
84
724
485
4255
1.22
2.99
3.5
3.5
19.63
70.09
e6/l
2.53
356
3274
152
1163
1.35
2.88
3.4
3.5
88.86
85.73
ng/l
0.17
128
1001
1012
9555
1.24
2.87
23.6
21.8
13.68
13.75
%
0.86
1000
9430
284
2368
1.25
2.80
1.4
1.3
30.18
34.66
iu/ml
0.24
90
754
679
6182
1.20
2.77
16.0
15.9
1.25
1.26
inr
0.24
562
5135
308
2602
1.24
2.70
4.2
4.1
143.80
359.33
ng/l
3.33
257
2104
281
2354
1.24
2.65
1.8
1.8
1053.29
1173.25
nmol/l
1.44
189
1744
160
1250
1.32
2.64
1.9
2.4
34.64
36.53
u/l
0.25
131
1064
101
734
1.41
2.64
1.1
1.3
42.98
53.93
au/ml
—
6
57
216
1761
1.27
2.58
3.4
3.4
0.77
0.78
ug/l
0.03
161
1183
290
2451
1.23
2.52
1.4
1.5
2.54
2.48
g/l
0.18
170
1427
21
102
2.08
2.48
1.7
1.3
1.25
1.55
u/ml
0.09
12
52
746
6909
1.18
2.34
6.3
6.9
10.91
11.39
umol/l
0.88
691
6597
77
546
1.44
2.33
1.4
1.8
9.24
7.50
iu/ml
0.22
13
122
699
6447
1.17
2.28
2.8
2.7
—
—
—
0
0
58
396
1.49
2.15
1.2
1.4
—
—
—
0
0
39
244
1.62
2.12
1.4
1.3
—
—
—
0
0
10
37
2.72
2.07
2.0
1.1
13.64
8.84
ug/l
—
10
37
6
15
4.01
2.04
1.0
1.1
—
—
—
0
0
6
15
4.01
2.04
1.0
1.1
—
—
—
0
0
12
51
2.37
1.95
2.7
3.4
525.58
1357.47
u/ml
1.50
12
51
101
775
1.33
1.94
3.6
3.6
4.48
4.46
pmol/l
0.09
90
686
46
310
1.50
1.85
1.2
1.2
—
—
—
0
0
259
2232
1.20
1.84
1.3
1.3
7.98
12.95
u/ml
0.50
76
797
550
5039
1.15
1.83
4.3
4.0
150.30
63.92
ng/l
0.40
415
3798
43
287
1.51
1.81
1.3
1.4
—
—
—
0
0
72
532
1.37
1.78
1.6
2.6
10.37
10.41
g/l
0.03
62
472
123
984
1.28
1.76
2.3
2.9
10.99
10.73
g/l
0.24
114
904
28
173
1.63
1.65
1.6
1.3
—
—
—
0
0
16
289
0.55
1.62
3.4
1.5
166.64
865.83
e6/l
0.83
11
223
16
288
0.55
1.61
3.3
1.4
62.91
34.58
e6/l
0.19
11
209
332
2958
1.16
1.59
5.9
5.9
2.49
2.94
ug/l
0.38
301
2638
213
1834
1.19
1.54
6.0
5.2
1.01
1.03
mmol/l
0.45
189
1678
26
161
1.63
1.53
1.2
1.5
—
—
—
0
0
26
161
1.63
1.53
1.2
1.5
—
—
—
0
0
7
27
2.60
1.51
1.3
1.3
—
—
—
0
0
151
1262
1.22
1.50
2.9
2.6
68.41
70.34
e9/l
0.29
107
946
26
163
1.61
1.47
1.2
1.5
—
—
—
0
0
52
379
1.39
1.44
3.0
3.3
1.60
2.07
index
0.22
20
195
79
616
1.30
1.42
1.8
2.6
3.58
3.71
g/l
0.47
71
562
49
355
1.39
1.41
1.7
2.0
3.89
21.01
iu/l
0.51
21
138
79
617
1.30
1.40
1.8
2.6
7.59
7.44
g/l
0.32
71
562
79
617
1.30
1.40
1.8
2.6
4.16
4.24
g/l
0.47
71
562
452
4149
1.13
1.40
2.9
3.2
29.57
34.05
u/l
1.00
419
3908
60
451
1.35
1.39
1.7
1.6
15.82
16.69
u/ml
0.06
14
76
180
1543
1.19
1.38
7.0
7.3
—
—
—
0
0
174
1487
1.20
1.38
2.0
2.7
8.38
7.70
umol/l
0.10
152
1311
25
158
1.59
1.38
2.2
1.6
39.81
32.37
ng/l
0.22
25
158
460
4233
1.13
1.36
2.2
2.2
163.27
219.54
u/l
1.44
416
4010
5
17
2.95
1.36
1.8
1.6
—
—
—
0
0
0
39
0.00
1.34
0.0
3.4
—
9.83
—
0
39
0
39
0.00
1.34
0.0
3.4
—
4.93
—
0
39
148
1251
1.21
1.33
2.8
2.3
395.20
381.91
nmol/l
0.34
137
1159
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
48
354
1.37
1.27
1.2
1.1
—
—
—
0
0
96
780
1.25
1.26
1.5
1.3
357.68
176.01
u/ml
0.87
88
715
26
170
1.54
1.26
1.2
1.5
—
—
—
0
0
26
170
1.54
1.26
1.2
1.5
—
—
—
0
0
64
494
1.31
1.26
4.6
4.0
25.76
24.92
mmol/l
1.38
58
454
320
2898
1.14
1.21
2.9
3.0
2.48
2.46
mmol/l
1.64
276
2618
13
71
1.84
1.19
1.1
1.3
—
—
—
0
0
13
71
1.84
1.19
1.1
1.3
—
—
—
0
0
100
823
1.23
1.19
1.1
1.2
229.79
129.68
u/ml
1.03
29
319
328
2981
1.13
1.17
2.8
2.8
5.02
6.18
e6/l
0.85
292
2711
79
634
1.26
1.17
1.4
1.8
1.46
1.54
g/l
0.36
72
550
130
1101
1.20
1.16
5.1
3.8
1.23
1.23
mmol/l
0.01
108
945
47
352
1.35
1.15
1.2
1.1
—
—
—
0
0
34
241
1.42
1.14
1.2
1.2
100.38
30.21
u/l
0.50
26
208
5
115
0.43
1.12
1.0
1.3
—
—
—
0
0
44
328
1.35
1.11
3.9
3.5
0.82
0.78
nmol/l
0.23
39
266
86
703
1.24
1.10
3.6
3.5
1.02
1.02
ratio
0.62
75
647
25
170
1.48
1.05
1.2
1.5
—
—
—
0
0
50
385
1.31
1.04
4.1
2.9
1.49
1.58
mg/l
0.31
44
348
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
17
106
1.61
1.03
1.3
1.1
3.06
5.71
u/ml
0.52
11
40
40
299
1.35
1.01
1.8
1.6
—
—
—
0
0
179
1578
1.15
1.01
4.1
4.5
224.58
248.09
u/l
1.68
172
1492
25
172
1.46
1.00
1.5
1.3
276.94
273.52
mosm/kgh2o
0.44
16
128
51
397
1.30
0.99
1.6
1.4
—
—
—
0
0
106
897
1.20
0.99
4.7
3.7
5.31
5.16
kpa
1.10
98
862
198
1763
1.14
0.98
1.6
1.8
—
—
—
0
0
92
772
1.21
0.94
4.5
3.6
2.45
1.94
mmol/l
0.68
72
582
15
93
1.62
0.94
1.5
1.5
112.93
90.72
ng/l
0.69
15
93
71
581
1.23
0.93
1.8
2.6
2.90
2.96
g/l
0.18
63
526
36
270
1.34
0.91
1.6
1.6
272.90
290.47
mu/l
0.27
31
244
53
421
1.27
0.90
1.6
1.5
289.04
280.83
ug/g
0.10
37
259
8
42
1.91
0.88
2.4
2.6
0.61
0.60
mmol/l
—
8
42
11
64
1.72
0.86
5.7
4.6
—
—
—
0
0
27
196
1.39
0.84
1.1
1.2
225.50
249.61
u/ml
0.17
16
110
624
5955
1.09
0.84
2.8
2.8
—
—
estimate
—
0
0
189
1698
1.13
0.84
1.5
1.5
—
—
—
0
0
19
129
1.48
0.83
1.3
1.0
2.24
0.85
u/ml
0.54
11
60
49
390
1.27
0.83
2.1
1.9
1.86
5.42
mg/l
1.76
40
303
45
355
1.28
0.82
1.6
1.5
109.08
0.24
iu/ml
—
10
60
117
1018
1.16
0.82
1.6
1.4
—
—
—
0
0
13
81
1.61
0.81
1.4
1.4
—
—
—
0
0
117
1019
1.16
0.81
3.1
2.7
62.75
62.91
ml/min/173m2
0.01
48
464
63
519
1.22
0.80
1.5
1.3
—
—
—
0
0
6
33
1.82
0.79
1.0
1.2
—
—
—
0
0
15
98
1.54
0.78
1.1
1.0
0.24
0.29
u/ml
—
6
31
0
26
0.00
0.78
0.0
7.1
—
74.95
—
0
21
23
165
1.40
0.78
1.3
1.6
—
—
—
0
0
18
257
0.70
0.77
1.6
1.1
0.55
0.68
ratio
—
5
39
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
18
124
1.46
0.75
1.3
1.2
—
68.29
—
0
7
17
116
1.47
0.74
1.3
1.0
5.27
2.07
u/ml
0.58
11
53
16
108
1.49
0.73
1.4
1.5
—
—
—
0
0
250
2304
1.10
0.72
3.1
3.2
0.82
0.82
mmol/l
0.02
234
2165
13
84
1.55
0.72
1.4
1.4
—
—
—
0
0
23
168
1.38
0.71
1.3
1.1
0.75
1.46
u/ml
0.76
13
83
65
545
1.20
0.71
2.0
2.7
0.50
1.38
g/l
1.53
55
473
54
445
1.22
0.70
1.5
2.6
0.00
0.00
g/l
-0.00
48
391
130
1156
1.14
0.70
1.6
1.8
1.37
1.49
%
1.09
110
981
153
1375
1.13
0.70
2.3
2.2
0.21
0.21
g/l
0.33
144
1289
102
893
1.15
0.68
1.6
1.7
—
—
—
0
0
7
42
1.67
0.68
1.3
1.7
64.00
738.95
nmol/24h
—
7
42
132
1180
1.13
0.66
2.8
2.7
4.49
4.49
kpa
0.02
127
1151
55
458
1.21
0.66
1.6
2.6
0.00
0.01
g/l
0.65
49
415
16
111
1.45
0.66
1.0
1.1
—
—
—
0
0
256
2377
1.10
0.64
4.3
4.9
23.70
21.47
%
1.48
125
1212
22
163
1.36
0.64
1.1
1.0
—
—
—
0
0
135
1212
1.13
0.64
2.1
3.1
66.89
66.54
g/l
0.22
122
1112
38
468
0.81
0.62
3.8
3.5
1.29
1.38
mmol/l
0.30
38
460
20
147
1.37
0.62
2.7
1.9
89.75
89.32
%
0.16
20
147
17
122
1.40
0.60
1.0
1.1
108.76
105.59
pmol/l
0.11
17
122
12
174
0.69
0.59
1.1
1.2
0.18
0.18
nmol/l
0.18
12
135
298
2798
1.08
0.59
1.8
1.8
42222678.65
20897933.75
pmol/l
0.21
225
2273
364
3446
1.08
0.58
4.2
3.7
0.01
0.03
estimate
0.32
134
1105
43
355
1.22
0.58
1.3
1.2
—
—
—
0
0
36
292
1.24
0.57
2.5
2.3
98.24
94.93
ug/min
0.02
17
168
54
457
1.19
0.57
1.7
3.6
1.73
3.20
ratio
0.95
32
266
15
207
0.72
0.57
1.1
1.2
—
0.49
nmol/l
—
0
12
59
504
1.18
0.56
2.1
3.8
38.69
66.58
mg/l
1.25
50
443
148
1350
1.11
0.55
3.1
3.3
2.02
1.95
mmol/l
0.09
126
1170
153
1400
1.10
0.54
3.0
3.3
5.91
5.79
kpa
0.85
148
1362
21
160
1.32
0.53
1.1
1.2
3.11
4.79
u/ml
—
9
67
9
62
1.45
0.53
1.0
1.1
—
—
—
0
0
13
91
1.43
0.53
1.4
1.4
—
—
—
0
0
19
143
1.33
0.52
1.1
1.0
1.46
1.86
eliau/ml
—
8
53
41
342
1.21
0.51
3.3
2.2
130.48
127.67
g/l
0.31
31
271
24
302
0.79
0.50
1.8
1.2
0.92
0.92
g/l
0.02
24
302
248
2329
1.08
0.50
1.7
1.9
—
—
—
0
0
14
189
0.74
0.48
3.9
2.0
33.64
32.35
pg
0.76
14
189
58
504
1.16
0.47
2.1
3.8
28.04
53.03
mg/l
2.15
49
443
5
81
0.62
0.46
1.0
1.1
—
—
—
0
0
18
138
1.31
0.45
3.9
2.5
—
—
—
0
0
8
121
0.66
0.45
1.0
1.5
—
—
—
0
0
8
121
0.66
0.45
1.0
1.5
—
—
—
0
0
8
121
0.66
0.45
1.0
1.5
—
—
—
0
0
20
156
1.29
0.45
1.1
1.1
—
—
—
0
0
31
256
1.22
0.44
1.5
1.9
—
—
—
0
0
104
946
1.11
0.43
10.6
8.9
1.24
1.24
%
0.02
104
940
51
443
1.16
0.43
1.7
1.6
0.27
0.35
mg/l
0.75
28
194
23
284
0.81
0.42
1.8
1.2
1.51
1.57
g/l
0.58
23
284
37
435
0.85
0.42
1.1
1.3
—
—
—
0
0
42
360
1.17
0.42
2.0
1.7
—
—
—
0
0
70
783
0.89
0.41
1.9
4.2
99.66
87.54
u/ml
0.05
65
756
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
10.92
—
0
16
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
60
1.34
0.40
2.0
1.9
—
—
—
0
0
37
315
1.18
0.40
1.7
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
120
1107
1.09
0.39
2.8
3.2
196.44
193.79
ng/l
0.03
110
1016
203
1914
1.07
0.38
1.5
1.4
—
—
—
0
0
337
3231
1.06
0.38
2.4
2.4
—
—
—
0
0
16
203
0.79
0.38
1.1
1.2
0.56
9.42
nmol/l
0.50
16
194
39
336
1.17
0.37
1.9
1.7
5576.32
13370.59
e6/l
2.00
28
232
41
355
1.16
0.37
1.7
1.4
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
6.40
9.41
mm/h
—
5
37
428
4135
1.05
0.36
2.6
2.6
58.08
80.49
u/l
0.60
372
3817
11
81
1.36
0.36
2.1
1.4
0.89
1.14
promille
0.32
11
69
279
2918
0.94
0.36
4.6
4.5
1.02
1.02
kg/l
2.36
197
1954
15
190
0.79
0.35
1.1
1.1
6.14
25.08
au/ml
—
5
43
5
79
0.63
0.35
1.2
1.3
—
—
—
0
0
5
79
0.63
0.35
1.2
1.3
—
—
—
0
0
386
3724
1.05
0.35
4.6
4.4
0.00
0.00
estimate
1.23
141
1287
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
43
1.40
0.35
1.0
3.4
168.67
144.54
%
—
6
43
173
1630
1.07
0.34
7.9
7.4
5.13
5.12
kpa
0.05
167
1573
173
1630
1.07
0.34
7.9
7.4
13.23
12.18
kpa
1.10
166
1576
122
1135
1.08
0.34
2.0
2.5
9.68
7.62
ug/l
0.31
102
1006
20
163
1.23
0.34
1.0
1.1
1.38
1.54
g/l
1.13
14
146
171
1613
1.07
0.33
7.8
7.4
0.77
1.01
mmol/l
0.39
150
1349
12
92
1.31
0.32
1.2
1.2
6.78
2.72
nmol/l
—
5
17
22
185
1.19
0.29
1.5
1.4
176.14
161.47
au/ml
—
7
62
7
57
1.23
0.29
1.3
1.4
—
—
—
0
0
7
57
1.23
0.29
1.3
1.4
—
—
—
0
0
21
176
1.20
0.29
1.5
1.9
189.52
211.90
pmol/l
0.43
21
165
39
346
1.13
0.28
1.3
1.5
—
—
—
0
0
28
243
1.16
0.27
5.5
5.3
208.80
243.45
iu/ml
—
5
33
5
73
0.68
0.26
1.0
1.1
—
—
—
0
0
22
188
1.17
0.25
1.5
1.4
30.25
32.98
g/l
0.38
17
171
27
235
1.15
0.25
1.3
1.7
—
—
—
0
0
75
695
1.08
0.25
2.2
2.3
14.34
12.87
nmol/l
0.73
64
622
9
76
1.19
0.24
1.3
1.8
—
—
—
0
0
21
180
1.17
0.23
1.2
1.1
—
—
—
0
0
17
143
1.19
0.23
1.4
1.4
6.65
6.43
mmol/l
0.16
17
134
117
1108
1.06
0.23
2.5
2.4
0.38
0.56
e6/l
0.46
111
1055
11
135
0.81
0.22
1.8
1.6
—
—
—
0
0
22
252
0.87
0.22
1.4
1.4
—
—
—
0
0
39
353
1.11
0.21
1.4
1.6
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
12
145
0.83
0.21
1.2
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.25
0.20
1.0
1.3
6.52
5.88
u/l
—
10
66
0
14
0.00
0.20
0.0
1.0
—
30.92
—
0
9
23
202
1.14
0.20
2.9
1.8
1.82
1.64
mmol/l
0.22
23
197
9
112
0.80
0.20
1.7
1.6
—
—
—
0
0
502
4927
1.03
0.20
4.7
4.2
0.07
0.07
estimate
0.04
134
1147
20
174
1.15
0.19
1.3
1.6
—
—
—
0
0
33
298
1.11
0.19
1.2
1.3
—
—
—
0
0
6
53
1.13
0.18
1.0
1.3
—
—
—
0
0
71
754
0.94
0.18
2.5
2.5
1.14
1.13
%
0.03
71
749
100
952
1.05
0.18
2.4
2.0
3.20
3.39
ratio
1.16
81
771
14
119
1.18
0.17
1.6
1.3
1.60
1.38
nmol/l
0.32
14
101
26
289
0.90
0.17
1.4
1.4
—
—
—
0
0
7
62
1.13
0.17
1.3
1.2
118.71
432.68
u/l
—
7
57
7
62
1.13
0.17
1.4
1.3
35.00
30.19
umol/l
—
7
57
19
167
1.14
0.17
1.2
1.2
2.33
2.57
u/ml
—
6
49
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
69
0.72
0.17
1.0
1.2
—
—
—
0
0
5
70
0.71
0.16
1.8
1.8
—
—
—
0
0
8
71
1.13
0.16
1.1
1.9
—
—
—
0
0
171
1655
1.04
0.16
1.7
1.9
—
—
—
0
0
48
514
0.93
0.16
1.9
2.0
—
—
—
0
0
44
472
0.93
0.15
1.7
1.9
—
—
—
0
0
51
478
1.07
0.15
2.4
2.9
—
—
—
0
0
14
121
1.16
0.15
1.1
1.4
12163.25
191586.90
e6/l
—
8
80
61
576
1.06
0.15
1.0
1.0
—
—
—
0
0
9
82
1.10
0.15
1.2
1.3
—
—
—
0
0
9
82
1.10
0.15
1.2
1.3
—
—
—
0
0
54
572
0.94
0.14
2.9
3.6
2344.91
2490.76
u/ml
0.02
41
497
17
151
1.13
0.13
1.1
1.3
21874.29
49388.20
e6/l
—
7
76
19
172
1.11
0.11
1.3
1.3
1379.11
1899.29
e6/l
—
9
111
103
996
1.04
0.11
1.9
1.7
—
—
—
0
0
72
692
1.04
0.10
2.0
1.8
3.35
3.51
mmol/l
0.57
53
507
11
97
1.14
0.09
1.6
2.3
490.00
637.66
ml
—
6
64
14
126
1.11
0.09
1.1
1.2
—
—
—
0
0
12
134
0.89
0.08
1.2
1.7
—
—
—
0
0
6
58
1.03
0.08
1.0
1.3
—
—
—
0
0
5
64
0.78
0.08
2.4
2.1
237.20
236.19
e6/l
—
5
54
15
164
0.91
0.08
2.1
1.4
—
—
—
0
0
8
75
1.07
0.07
2.9
2.5
—
—
—
0
0
10
112
0.89
0.07
1.1
1.5
—
—
—
0
0
7
85
0.82
0.07
1.1
1.3
10.30
9.64
mmol/l
—
7
77
9
87
1.03
0.07
1.2
1.2
—
—
—
0
0
38
397
0.96
0.07
1.4
1.6
—
—
—
0
0
66
680
0.97
0.06
2.0
1.8
—
—
—
0
0
12
109
1.10
0.06
1.9
2.2
3.17
1.91
u/field
—
6
57
11
121
0.91
0.06
1.5
1.4
39.20
30.49
u/l
0.51
11
98
30
314
0.95
0.05
1.4
1.5
—
—
—
0
0
18
192
0.94
0.05
2.6
2.6
—
567.08
—
0
13
18
169
1.07
0.05
2.3
2.6
11.29
26.86
mg/l
—
7
61
153
1550
0.99
0.04
4.0
4.5
6.42
19.84
ug/l
1.46
114
1281
10
109
0.92
0.04
1.1
1.2
—
—
—
0
0
14
131
1.07
0.03
2.2
3.3
8.57
11.51
index
—
7
76
35
339
1.03
0.03
1.3
1.5
—
—
—
0
0
27
262
1.03
0.02
1.1
1.3
—
—
—
0
0
27
262
1.03
0.02
1.1
1.3
—
—
—
0
0
122
1230
0.99
0.01
8.3
7.0
9.88
9.84
mmol/l
0.03
115
1180
14
133
1.05
0.01
4.0
4.1
—
—
—
0
0
61
602
1.01
0.01
1.8
1.7
—
—
—
0
0
21
204
1.03
0.00
1.4
1.5
—
—
—
0
0
25
256
0.98
0.00
1.4
1.6
0.68
0.86
nmol/l
1.24
20
211
31
316
0.98
0.00
1.2
1.5
71.14
248.09
pmol/l
3.07
31
309
10
98
1.02
0.00
1.2
1.0
—
—
—
0
0
10
98
1.02
0.00
1.5
1.2
8.10
13.43
u/l
—
10
90
10
98
1.02
0.00
1.1
1.2
—
—
—
0
0
10
102
0.98
0.00
1.1
1.2
—
—
—
0
0
10
102
0.98
0.00
1.1
1.2
—
—
—
0
0
10
99
1.01
0.00
1.1
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
43
431
1.00
0.00
3.7
3.1
0.31
0.37
iu/ml
0.76
25
246
24
243
0.99
0.00
1.3
1.5
—
—
—
0
0
24
235
1.02
0.00
1.1
1.3
215.08
252.29
miu/ml
—
9
100
0
6
0.00
0.00
0.0
5.7
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
7.61
—
0
7
6
64
0.94
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.3
1.1
—
—
—
0
0
8
89
0.90
-0.00
1.5
1.5
—
—
—
0
0
9
97
0.93
-0.00
1.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.6
—
—
—
0
0
5
51
0.98
-0.00
1.6
1.6
73.54
48.58
ug/l
—
5
51
7
69
1.01
-0.00
1.0
1.6
—
—
—
0
0
7
69
1.01
-0.00
1.0
1.6
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.6
—
—
—
0
0
6
61
0.98
-0.00
1.2
5.1
—
83.70
—
0
10
7
69
1.01
-0.00
1.0
1.6
—
—
—
0
0
6
62
0.97
-0.00
3.5
1.8
39.38
40.37
g/l
—
6
62
5
55
0.91
-0.00
1.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
76
0.92
-0.00
2.1
3.7
0.71
0.95
index
—
7
76
7
69
1.01
-0.00
1.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint H7_KERATOCONUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_KERATOCONUS | 0.924 [0.81, 1.05] | 0.231 |
| Birth year | 0.998 [0.99, 1.01] | 0.592 |
During the follow-up period (1.1.1998 — 31.12.2019), 527 out of 3224 females with H7_KERATOCONUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_KERATOCONUS | 0.883 [0.73, 1.07] | 0.197 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 245 out of 1522 males with H7_KERATOCONUS died.
Mortality risk
Mortality risk for people of age
years, who have H7_KERATOCONUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.166% |
| 5 | 0.582% | 1.079% |
| 10 | 1.379% | 2.724% |
| 15 | 2.655% | 5.079% |
| 20 | 4.734% | 8.566% |
Relationships between endpoints
↥Index endpoint: H7_KERATOCONUS – Hereditary corneal dystrophies
GWS hits: 19
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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