No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
358 |
4. Check minimum number of eventsNone |
358 |
5. Include endpointsNone |
358 |
6. Filter based on genotype QC (FinnGen only) |
319 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Delayed puberty
based on the number of shared cases.
Similar with more cases:
- Disorders of puberty
- Disorders of puberty, all
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7828 | 1705 | 6119 |
| Only index persons | 7752 | 1673 | 6079 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.05 | 0.17 |
| Only index persons | 0.20 | 0.06 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 14.73 | 13.87 | 14.97 |
| Only index persons | 14.73 | 13.86 | 14.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 319 | 139 | 180 |
| Unadjusted period prevalence (%) | 0.07 | 0.05 | 0.08 |
| Median age at first event (years) | 14.63 | 14.21 | 14.97 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 330
- Matched controls
- 3300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E30.00
ICD-10 Finland
Familial delayed puberty
1786.9
198.5
173
*
E30.09
ICD-10 Finland
Delayed puberty NOS
3515.9
197.8
171
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
84.7
170.7
92
15
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
29.2
147.6
108
54
E34.35
ICD-10 Finland
Abnormal growth retardation
625.5
55.2
53
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
30.7
29
*
H01AC01
ATC
somatropin; parenteral
+∞
25.3
24
*
2590A
ICD-9 Finland
Other endocrine disorders, Delay in sexual development and puberty, not elsewhere classified
+∞
20.0
19
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
212.2
19.8
20
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
55.8
18.2
21
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
53.0
17.2
20
*
N91.0
ICD-10 Finland
Primary amenorrhoea
35.3
15.9
20
6
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
27.1
13.5
18
7
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
12.6
12
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
11.5
11
*
E34.30
ICD-10 Finland
Short stature NOS
124.2
11.5
12
*
E29.1
ICD-10 Finland
Testicular hypofunction
26.1
11.2
15
6
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
13.5
10.8
18
14
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.6
10.2
35
105
E30.0
ICD-10 Finland
Delayed puberty
+∞
9.4
9
*
301
Kela drug reimbursment
Growth hormone
+∞
9.4
9
*
E30.8
ICD-10 Finland
Other disorders of puberty
+∞
9.4
9
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.5
9.3
23
54
T10
ICPC
Growth delay
51.4
8.7
10
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.0
8.5
39
140
G03DB01
ATC
dydrogesterone; oral
3.7
8.4
27
77
E28.3
ICD-10 Finland
Primary ovarian failure
+∞
8.4
8
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
34.3
8.1
10
*
G03FB08
ATC
dydrogesterone and estrogen; systemic
22.7
8.1
11
5
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
7.6
103
604
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
7.3
7
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
6.6
55
265
ZXE00
NOMESCO Finland
One hour or less
1.9
6.5
117
750
WVA30, ,
SPAT
4.2
6.4
17
42
Z3231
NOMESCO Finland
Registered nurse
1.9
6.4
97
587
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
6.4
61
312
E30.1
ICD-10 Finland
Precocious puberty
+∞
6.3
6
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
7.9
6.2
13
17
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
92
128
9.58
66.33
3.0
1.8
7.87
7.94
iu/l
0.01
69
97
97
149
8.80
64.30
3.2
1.8
4.88
5.73
u/l
0.48
75
116
161
969
2.29
12.23
1.6
1.6
0.99
2.03
u/ml
0.91
39
242
254
1970
2.26
8.93
4.3
3.7
14.58
14.53
pmol/l
0.13
243
1786
138
899
1.92
7.48
8.9
8.6
1.21
1.21
mmol/l
0.44
116
797
99
580
2.01
7.28
2.4
2.6
2.37
2.37
mmol/l
0.03
92
545
149
1009
1.87
7.07
3.4
3.0
64.72
65.72
nmol/l
0.21
138
955
124
803
1.87
6.69
8.9
9.0
1.22
1.22
mmol/l
0.04
115
757
275
2301
2.17
6.53
5.1
4.3
2.00
1.74
mu/l
4.30
267
2174
302
2692
2.44
5.07
10.0
8.3
29.56
28.56
u/l
0.18
296
2615
325
3066
4.96
4.93
19.1
14.9
261.31
258.45
e9/l
0.34
319
2992
13
25
5.37
4.82
3.4
8.3
4.72
7.46
pmol/l
0.63
13
25
303
2717
2.41
4.80
13.1
9.7
67.08
70.81
umol/l
3.30
298
2676
325
3070
4.87
4.77
19.2
14.8
4.68
4.73
e12/l
1.19
319
2995
40
198
2.16
4.51
6.6
5.2
1.59
1.05
mmol/l
0.54
29
145
111
766
1.68
4.48
6.2
5.9
38.47
39.01
g/l
0.53
104
729
8
9
9.07
4.30
2.4
3.1
2.88
3.42
nmol/l
—
8
9
68
425
1.76
3.88
1.7
1.4
18.04
17.62
nmol/l
0.11
59
385
43
242
1.89
3.43
8.8
12.1
25.26
25.08
mmol/l
0.11
43
242
192
1594
1.49
3.12
8.1
6.4
96.52
83.59
u/l
2.16
184
1504
41
238
1.83
2.98
3.5
7.8
24.88
23.79
mmol/l
2.85
41
238
25
122
2.14
2.96
2.2
1.4
38.08
33.45
nmol/l
0.25
25
117
43
255
1.79
2.92
1.2
1.3
179.45
152.90
u/ml
0.16
16
95
12
38
3.24
2.88
5.3
4.4
83.42
100.71
%
1.01
12
38
181
1501
1.46
2.85
11.3
9.9
3.61
3.85
e9/l
0.81
154
1297
267
2396
1.60
2.84
13.1
9.6
3.91
3.89
mmol/l
0.66
255
2313
11
33
3.41
2.84
3.6
1.5
—
—
—
0
0
85
610
1.53
2.75
3.5
3.2
0.23
0.16
e6/l
0.25
61
426
9
24
3.82
2.69
1.2
1.2
—
—
—
0
0
196
1666
1.43
2.61
5.2
3.9
7.64
6.63
mm/h
0.56
180
1558
43
264
1.72
2.61
1.3
1.5
511.31
56431945.40
pmol/l
0.80
36
241
11
36
3.12
2.59
2.2
3.0
12.18
9.22
%
0.67
11
36
265
2402
1.52
2.40
13.2
9.5
139.66
139.61
mmol/l
0.15
256
2328
10
33
3.09
2.37
2.6
3.2
—
—
—
0
0
169
1420
1.39
2.29
3.5
3.4
68.57
64.42
ug/l
0.14
158
1360
95
722
1.44
2.29
4.2
3.5
—
—
—
0
0
91
686
1.45
2.29
1.9
1.5
95.73
97.81
pmol/l
0.15
45
374
65
460
1.51
2.23
3.0
2.6
233.34
266.40
u/l
0.19
65
449
12
48
2.56
2.21
1.5
1.3
265.40
372.79
ug/g
—
6
19
7
19
3.74
2.16
1.6
1.3
—
—
nmol/l
—
0
0
35
216
1.69
2.11
4.4
5.8
191.78
1230.17
ng/l
0.65
27
150
6
15
4.05
2.05
1.7
1.1
—
—
—
0
0
6
15
4.05
2.05
3.3
4.1
133.00
174.39
ug/l
—
6
15
18
93
1.99
1.89
1.1
1.1
—
12.15
—
0
11
9
34
2.69
1.88
1.6
2.9
—
—
—
0
0
9
35
2.61
1.81
1.4
1.4
—
—
—
0
0
7
23
3.09
1.81
5.1
1.6
—
—
—
0
0
238
2167
1.35
1.67
10.5
7.5
109.14
107.56
ml/min/173m2
0.64
194
1773
208
1863
1.32
1.60
4.1
3.3
36.71
36.08
mmol/mol
0.37
197
1787
22
130
1.74
1.57
2.0
1.6
—
—
—
0
0
79
620
1.36
1.54
2.6
2.6
2.42
2.35
mg/l
0.10
64
549
38
261
1.52
1.52
1.6
2.0
2.42
2.40
mmol/l
0.68
33
228
6
21
2.89
1.51
1.7
1.1
—
—
—
0
0
16
87
1.88
1.48
1.6
1.2
0.30
0.33
ug/l
—
6
19
6
22
2.76
1.44
1.7
1.1
—
—
—
0
0
9
40
2.28
1.41
1.2
1.2
—
—
—
0
0
9
40
2.28
1.41
1.2
1.2
—
—
—
0
0
5
17
2.97
1.36
2.4
4.6
441.20
563.41
u/ml
—
5
17
5
17
2.97
1.36
5.4
5.1
2.20
1.06
index
—
5
17
285
2702
1.40
1.30
13.6
10.1
18.94
21.76
mg/l
0.85
221
2000
8
34
2.39
1.30
1.1
1.1
—
—
—
0
0
11
56
2.00
1.23
1.0
1.4
—
—
—
0
0
14
78
1.83
1.23
1.2
1.2
—
—
—
0
0
10
51
1.99
1.12
3.9
1.3
—
—
—
0
0
88
734
1.27
1.11
3.7
2.3
0.11
0.00
estimate
0.49
28
218
41
306
1.39
1.10
5.8
7.4
0.84
0.82
mmol/l
0.40
41
291
29
205
1.45
1.05
3.8
3.6
0.22
0.23
g/l
0.63
29
192
21
139
1.55
1.03
4.3
2.3
—
—
—
0
0
29
207
1.44
1.00
2.9
1.7
—
—
—
0
0
37
277
1.38
0.99
1.1
1.0
—
—
—
0
0
29
210
1.42
0.94
2.9
1.6
—
—
—
0
0
6
27
2.24
0.94
2.8
1.8
—
—
—
0
0
10
55
1.84
0.93
5.8
6.1
359.90
408.90
umol/l
—
10
49
10
167
0.59
0.87
1.6
2.0
—
—
—
0
0
138
1236
1.20
0.87
6.1
5.9
6.84
6.20
mmol/l
0.88
124
1120
11
64
1.74
0.87
3.9
1.6
—
—
—
0
0
218
2039
1.20
0.85
2.9
2.6
5.44
5.48
mmol/l
0.18
207
1883
41
321
1.32
0.84
7.1
5.3
5.83
15.59
mg/mmol
1.23
35
248
17
113
1.53
0.84
2.5
2.7
81.86
92.67
ml/min/173m2
—
7
42
21
293
0.70
0.83
1.5
1.5
—
—
—
0
0
32
416
0.74
0.83
1.7
1.5
3.38
3.45
ratio
0.11
23
292
23
164
1.43
0.82
1.9
1.7
—
—
—
0
0
25
183
1.40
0.78
1.1
1.1
8.36
9.63
u/ml
0.13
15
138
19
133
1.45
0.75
1.7
1.4
—
—
—
0
0
5
24
2.10
0.75
1.4
1.1
—
—
—
0
0
5
24
2.10
0.75
1.4
1.1
—
—
—
0
0
9
55
1.65
0.74
1.3
1.2
—
—
—
0
0
7
38
1.86
0.74
3.3
1.8
0.32
1.41
ug/l
—
7
33
5
25
2.01
0.73
1.4
1.1
—
—
—
0
0
10
60
1.69
0.73
4.1
1.6
—
—
—
0
0
101
1134
0.84
0.72
3.3
2.5
—
—
—
0
0
26
195
1.36
0.72
1.3
1.8
0.16
0.26
mg/l
1.06
11
94
46
376
1.26
0.70
3.1
2.8
0.23
0.52
e6/l
1.56
16
176
7
41
1.72
0.70
3.7
4.1
7.26
8.48
u/ml
—
7
41
12
77
1.58
0.69
1.2
1.5
—
—
—
0
0
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
28
215
1.33
0.67
11.2
10.7
107.21
104.94
mmol/l
0.88
28
215
7
43
1.64
0.67
9.9
1.5
13.47
12.75
%
—
7
43
17
120
1.44
0.66
1.1
1.1
12.23
9.84
u/ml
—
10
67
15
212
0.69
0.66
1.5
1.5
—
—
—
0
0
45
371
1.25
0.65
3.1
2.9
3.35
2.77
e6/l
0.14
17
171
5
29
1.73
0.64
1.2
2.7
0.73
0.66
e9/l
—
5
29
27
343
0.77
0.62
1.4
1.4
3.31
3.34
mmol/l
0.05
17
221
50
420
1.22
0.61
1.5
1.6
—
—
—
0
0
37
447
0.81
0.57
1.6
1.6
1436.69
949.06
mu/l
1.37
32
397
6
38
1.59
0.54
4.3
1.4
—
—
—
0
0
23
180
1.30
0.51
1.1
1.1
3.53
1.05
u/ml
0.80
14
111
136
1261
1.13
0.50
4.0
3.2
0.09
0.00
estimate
0.49
32
246
57
651
0.85
0.50
3.6
2.9
1.02
1.02
kg/l
1.40
34
387
135
1254
1.13
0.48
4.0
3.1
0.00
0.00
estimate
-0.00
32
250
97
1060
0.88
0.47
3.0
2.4
—
—
—
0
0
60
528
1.17
0.46
2.8
2.3
57.12
15.00
ng/l
0.47
27
205
20
156
1.30
0.46
3.6
2.1
31.79
31.24
%
0.07
14
117
12
86
1.41
0.45
1.1
1.2
—
—
—
0
0
10
69
1.46
0.44
1.5
1.6
—
—
—
0
0
58
511
1.16
0.44
1.6
1.8
1.46
1.38
%
0.43
52
466
35
295
1.21
0.44
2.9
1.8
—
—
—
0
0
11
78
1.42
0.43
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
101.27
—
0
15
11
79
1.41
0.41
1.2
1.1
—
—
—
0
0
25
205
1.24
0.40
1.2
1.2
9.25
3.29
u/ml
0.44
14
134
15
115
1.32
0.39
7.1
2.5
0.14
0.15
e6/l
0.06
15
107
17
133
1.29
0.39
5.4
7.0
97.59
96.19
%
0.09
17
133
133
1248
1.11
0.39
4.0
3.1
0.00
0.00
estimate
-0.00
32
262
26
216
1.22
0.38
1.2
1.4
327.20
268.07
miu/ml
0.22
11
114
9
68
1.33
0.38
2.1
3.1
0.75
0.65
nmol/l
—
9
55
18
221
0.80
0.34
1.4
1.5
1.04
0.98
ratio
0.19
13
138
18
221
0.80
0.34
1.4
1.5
1.40
1.19
ratio
0.34
13
138
18
221
0.80
0.34
1.4
1.5
1.45
1.25
ratio
0.35
13
138
11
82
1.35
0.34
1.6
1.7
—
—
—
0
0
17
136
1.26
0.34
1.1
1.1
8.25
6.22
u/ml
0.24
12
85
62
682
0.89
0.33
3.1
2.5
—
—
—
0
0
6
86
0.69
0.33
1.0
2.2
34.67
36.94
u/l
—
6
81
13
101
1.30
0.32
1.1
1.4
—
—
—
0
0
15
120
1.26
0.30
1.1
1.0
0.04
0.51
u/ml
—
6
47
22
185
1.20
0.30
1.1
1.1
10.81
2.51
u/ml
1.22
14
120
18
216
0.82
0.29
1.7
1.7
—
—
—
0
0
7
57
1.23
0.29
1.4
1.6
—
—
—
0
0
87
813
1.10
0.27
1.7
1.7
1.30
1.35
mmol/l
0.17
82
739
15
122
1.24
0.27
1.3
1.8
3.96
3.42
mg/l
—
9
75
99
934
1.09
0.25
3.8
2.8
0.11
0.00
estimate
0.46
28
226
9
73
1.24
0.25
6.2
6.6
—
771.50
—
0
8
225
2194
1.08
0.24
3.6
3.0
2.65
2.75
mmol/l
1.24
216
2098
5
39
1.29
0.23
1.4
1.7
5.36
7.37
mmol/l
—
5
34
18
153
1.19
0.23
1.3
1.1
0.95
0.89
g/l
0.43
18
153
5
40
1.25
0.22
5.2
1.7
—
—
—
0
0
5
40
1.25
0.22
5.2
1.8
—
—
—
0
0
14
116
1.22
0.22
6.4
5.4
205.21
166.51
%
1.09
14
116
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
8
101
0.79
0.21
1.1
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
68
638
1.08
0.20
4.5
3.2
0.00
0.00
estimate
0.50
31
248
15
176
0.85
0.20
1.8
1.6
58.76
56.71
ug/l
0.08
15
176
110
1052
1.07
0.20
2.6
3.0
—
—
estimate
—
0
0
17
194
0.87
0.17
1.6
1.8
—
—
—
0
0
20
225
0.88
0.17
1.6
2.0
—
—
—
0
0
8
68
1.18
0.16
12.4
5.3
56.59
53.19
%
—
8
68
6
80
0.75
0.15
1.2
1.1
—
2.59
—
0
8
271
2742
0.93
0.15
4.2
3.9
—
—
—
0
0
12
138
0.86
0.13
1.4
1.2
—
5.87
—
0
12
17
152
1.12
0.12
1.1
1.0
1.45
1.47
g/l
0.09
17
152
30
323
0.92
0.12
2.3
2.5
17008.09
6375.68
u/l
0.51
11
144
37
347
1.07
0.12
3.7
3.3
174.14
977.73
ng/l
1.09
21
163
11
96
1.15
0.10
22.3
17.7
0.52
0.69
%
1.79
11
96
57
546
1.05
0.10
2.2
2.6
—
—
—
0
0
24
258
0.92
0.09
1.3
1.3
—
—
—
0
0
5
47
1.06
0.09
3.0
1.2
—
—
—
0
0
11
97
1.14
0.09
22.3
17.6
96.29
94.29
%
1.94
11
97
6
55
1.09
0.09
1.3
1.1
—
2.62
—
0
24
47
490
0.95
0.08
3.1
2.8
0.87
1.14
mg/l
0.44
35
326
129
1269
1.03
0.06
2.3
1.9
—
—
—
0
0
187
1888
0.98
0.05
4.0
3.2
35.37
29.89
u/l
0.68
180
1828
222
2205
1.02
0.04
3.6
3.0
4.46
4.51
mmol/l
0.41
215
2120
220
2185
1.02
0.04
3.5
2.9
1.47
1.38
mmol/l
2.90
213
2092
16
168
0.95
0.02
2.2
1.5
165.63
191.49
u/ml
—
10
90
200
2008
0.99
0.01
3.2
2.6
1.12
1.16
mmol/l
0.27
194
1916
14
146
0.96
0.00
1.5
1.3
—
—
—
0
0
10
98
1.02
0.00
23.6
17.4
1.05
1.31
%
—
10
98
14
139
1.01
0.00
1.3
1.3
—
—
—
0
0
15
146
1.03
0.00
1.7
1.4
—
—
—
0
0
14
136
1.03
0.00
4.3
4.0
—
—
—
0
0
59
594
0.99
0.00
2.8
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
1.19
—
0
6
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
11.43
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
4.73
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
10.4
—
0.86
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
5
54
0.92
-0.00
1.4
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
8.5
8.5
—
4633.40
—
0
5
20
200
1.00
-0.00
1.5
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
2.3
1.2
—
20.50
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint E4_DELPUB and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_DELPUB | 1.963 [1.44, 2.68] | < 0.001 |
| Birth year | 0.985 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 5417 males with E4_DELPUB died.
Mortality risk
Mortality risk for people of age
years, who have E4_DELPUB.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.338% |
| 5 | No data | 2.166% |
| 10 | No data | 5.179% |
| 15 | No data | 10.013% |
| 20 | No data | 16.731% |
Relationships between endpoints
↥Index endpoint: E4_DELPUB – Delayed puberty
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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