Pleural plaque

J10_PLEURPLAGUE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J92
  • Cause of death: ICD-10 J92

2 out of 7 registries used, show all original rules.

4347

4. Check minimum number of events

None

4347

5. Include endpoints

None

4347

6. Filter based on genotype QC (FinnGen only)

3945

Control definitions (FinnGen only)

Control exclude
J10_PLEURA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J90-J94
Name in latin
Lamellae pleurae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22511 3209 19103
Only index persons 19742 2946 16796
Unadjusted period prevalence (%)
Whole population 0.47 0.09 0.53
Only index persons 0.56 0.11 0.64
Median age at first event (years)
Whole population 70.41 72.57 70.00
Only index persons 69.71 72.31 69.25

-FinnGen-

Key figures

All Female Male
Number of individuals 3945 439 3506
Unadjusted period prevalence (%) 1.45 0.16 1.61
Median age at first event (years) 70.38 70.56 70.35

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4021
Matched controls
40210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R03BB04
ATC
tiotropium bromide; inhalant
4.1
310.5
1059
3192
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
4755.1
307.7
2905
22
J94.8
ICD-10 Finland
Other specified pleural conditions
180.6
307.7
238
14
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
270.6
307.7
456
19
Z57.2
ICD-10 Finland
Occupational exposure to dust
132.0
307.7
271
22
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.3
307.7
1381
3084
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
11.5
307.7
439
424
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.2
307.7
1226
3816
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.4
307.7
894
984
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
100.6
307.7
578
67
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.2
307.7
898
2112
J92.9
ICD-10 Finland
Pleural plaque without asbestos
2839.6
307.7
1421
8
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.0
293.6
567
1066
R03AC02
ATC
salbutamol; inhalant
3.3
286.0
2473
13211
XG410
NOMESCO Finland
Flow-volume spirometry
6.9
274.5
451
720
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.6
257.8
531
1056
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8.2
246.9
343
453
GD1AD
NOMESCO Finland
Thorax CT examination
4.9
243.8
607
1420
R06.0
ICD-10 Finland
Dyspnoea
2.9
218.5
1663
7954
XX1AW
NOMESCO Finland
Written report from X-ray examination without contrast peformed elsewhere
32.2
216.3
140
45
J96.1
ICD-10 Finland
Chronic respiratory failure
1078.6
211.3
205
*
TGC00
NOMESCO Finland
Bronchial lavation
6.9
193.3
311
482
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
7.0
188.2
299
457
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.3
180.3
523
1366
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
157.2
2614
17276
TGA30
NOMESCO Finland
Thoracocentesis
39.3
157.0
96
25
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.7
151.0
1058
4702
H02AB06
ATC
prednisolone; systemic
2.3
139.9
2248
14346
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.6
135.2
339
786
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
132.6
933
4124
Z57.3
ICD-10 Finland
Occupational exposure to other air contaminants
42.4
131.6
79
19
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.8
127.1
792
3287
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.4
126.9
262
515
XX1XW
NOMESCO Finland
Extensive written report from radiologist
6.4
123.1
210
344
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.5
122.7
455
1397
J45.1
ICD-10 Finland
Nonallergic asthma
3.5
112.7
416
1271
R05
ICD-10 Finland
Cough
2.4
107.6
986
4870
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.7
101.8
193
350
J92
ICD-10 Finland
Pleural plaque
1013.6
101.6
99
*
R03BA08
ATC
ciclesonide; inhalant
3.4
100.5
386
1207
J98.1
ICD-10 Finland
Pulmonary collapse
133.4
97.5
104
8
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.3
97.4
262
639
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
6.3
91.5
156
255
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.0
86.6
261
692
R95
ICPC
Chron obstructive pulmonary disease
3.8
83.2
271
758
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.9
83.1
443
1672
R02
ICPC
Shortness of breath/dyspnoea
2.3
81.8
734
3549
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
79.7
1610
10467
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
8.4
78.8
103
125
C45.0
ICD-10 Finland
Mesothelioma of pleura
26.1
77.8
54
21
J94.9
ICD-10 Finland
Pleural condition, unspecified
265.7
76.7
78
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.1
76.6
166
339
R03AK07
ATC
formoterol and budesonide; inhalant
2.2
73.6
730
3666
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
4.4
72.8
186
435
5110B
ICD-9 Finland
Pleurisy, Without mention of effusion or current tuberculosis[PLEURA-ADHEESIOT]
+∞
72.1
69
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
8.6
71.8
92
109
R03AK08
ATC
formoterol and beclometasone; inhalant
4.0
71.3
211
551
GAC00
NOMESCO Finland
Biopsy of pleura
98.2
70.1
77
8
R04.2
ICD-10 Finland
Haemoptysis
3.2
69.4
296
982
J96.0
ICD-10 Finland
Acute respiratory failure
86.1
68.2
76
9
R03BA05
ATC
fluticasone; inhalant
2.2
67.9
680
3418
R03BA01
ATC
beclometasone; inhalant
2.2
58.5
584
2920
J01AA02
ATC
doxycycline; systemic
1.8
57.5
2950
24291
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
4.4
57.5
148
348
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
7.0
55.9
85
123
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
5.9
55.4
101
176
A02BC02
ATC
pantoprazole; systemic
1.7
52.9
2704
21943
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
5.9
51.7
93
160
SPAT1263
SPAT
Sampling
1.7
50.2
1671
12082
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
50.0
782
4567
J47
ICD-10 Finland
Bronchiectasis
4.1
48.9
136
339
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
48.0
185
576
R06.2
ICD-10 Finland
Wheezing
3.1
47.8
206
686
R03BA02
ATC
budesonide; inhalant
2.0
47.2
628
3471
J43.2
ICD-10 Finland
Centrilobular emphysema
9.6
46.9
55
58
J01CA04
ATC
amoxicillin; systemic
1.7
45.0
2880
24197
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
44.1
360
1649
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.4
43.6
112
263
R05
ICPC
Cough
1.7
42.7
895
5677
J43.9
ICD-10 Finland
Emphysema, unspecified
3.7
42.3
136
376
R03AC13
ATC
formoterol; inhalant
2.7
42.3
236
905
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
4.1
42.2
119
300
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
41.4
1729
13018
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.8
40.8
213
789
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
+∞
40.7
39
*
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
40.3
974
6409
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
40.1
896
5771
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
74.3
39.0
44
6
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.5
38.5
94
212
J01MA14
ATC
moxifloxacin; systemic
2.1
37.4
404
2063
R03AC18
ATC
indacaterol; inhalant
5.5
37.2
72
133
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
37.2
1735
13291
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
36.7
1198
8461
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
4.0
36.5
106
273
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.1
36.2
156
519
C03CA01
ATC
furosemide; systemic
1.5
34.9
1781
13844
SPAT1310
SPAT
Counselling related to known health issue
1.6
34.4
1219
8747
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
+∞
34.4
33
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
34.2
3386
30367
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.8
34.2
173
630
R96
ICPC
Asthma
2.1
34.0
364
1851
SPAT1058
SPAT
PEF monitoring instruction
2.1
33.2
335
1666
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
6.7
32.7
52
79
SPAT1312
SPAT
General health counselling
1.6
32.5
1154
8263
R03BB01
ATC
ipratropium bromide; inhalant
2.3
31.9
243
1078
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
30.3
242
1096
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
7.3
30.1
44
61
R03AK11
ATC
formoterol and fluticasone; inhalant
3.6
29.0
97
276
R01AD09
ATC
mometasone; nasal
1.5
28.6
1221
9048
R03AC03
ATC
terbutaline; inhalant
1.8
28.4
429
2447
TGD00
NOMESCO Finland
Needle biopsy of lung
6.5
28.1
46
72
XX1VW
NOMESCO Finland
Written report from radiologist
5.6
28.0
53
96
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
64.5
27.9
32
5
J93.9
ICD-10 Finland
Pneumothorax, unspecified
146.0
27.7
29
*
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
4.9
27.1
60
125
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.7
26.9
494
2984
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
26.8
1060
7711
XG466
NOMESCO Finland
Sleep oxymetry
2.8
26.8
137
502
M03BX02
ATC
tizanidine; oral
1.4
26.6
1742
13971
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
26.1
1503
11757
SPAT1301
SPAT
No procedures
1.5
25.8
1311
10012
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.9
25.5
76
200
G47.3
ICD-10 Finland
Sleep apnoea
1.5
25.4
839
5864
SPAT1153
SPAT
Removal of sutures
1.5
25.3
1335
10257
GA3AT
NOMESCO Finland
Pleural cytology with ultrasound guidance
9.4
25.3
30
32
SPAT1325
SPAT
Vaccination
1.4
25.2
1524
12006
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
25.2
1216
9186
M54.5
ICD-10 Finland
Low back pain
1.5
24.8
1083
8016
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
24.8
1283
9814
A02BC05
ATC
esomeprazole; systemic
1.4
24.7
1377
10676
J45
ICD-10 Finland
Asthma
2.0
24.4
298
1585
R03BB07
ATC
umeclidinium bromide; inhalant
4.5
24.0
58
130
J01MA12
ATC
levofloxacin; systemic
1.5
23.9
854
6058
C07AB07
ATC
bisoprolol; oral
1.4
23.9
2289
19481
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
5.5
23.8
46
85
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.2
23.7
213
1011
R03AL11
ATC
formoterol, glycopyrronium bromide and budesonide; inhalant
4.4
23.6
59
136
R99
ICPC
Respiratory disease other
3.1
23.6
97
315
R03DC03
ATC
montelukast; oral
1.8
23.5
413
2460
J43.8
ICD-10 Finland
Other emphysema
6.8
23.3
36
53
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
23.2
852
6074
J01FA06
ATC
roxithromycin; oral
1.4
23.2
1277
9854
GX1K5
NOMESCO Finland
Diffusion capacity
5.8
23.2
42
73
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
23.1
492
3089
J01DB01
ATC
cefalexin; oral
1.4
22.9
2949
26332
R03DA04
ATC
theophylline; systemic, rectal
2.0
22.8
277
1469
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
5.3
22.8
45
85
R29
ICPC
Respiratory symptom/complaint other
2.1
22.7
237
1192
J46
ICD-10 Finland
Status asthmaticus
3.0
22.7
100
338
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
22.6
1483
11793
356
Kela drug reimbursment
Nintedanib and pirfenidone
4.9
22.0
48
99
R28
ICPC
Limited function/disability (R)
3.5
22.0
74
212
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
6.2
21.9
37
60
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
21.8
440
2722
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
21.6
1123
8552
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
21.4
979
7277
SPAT1097
SPAT
Recording of ECG
1.5
21.2
654
4482
XG405
NOMESCO Finland
Education on PEF monitoring
3.6
21.1
69
194
J42
ICD-10 Finland
Unspecified chronic bronchitis
3.5
21.0
72
209
R03AC19
ATC
olodaterol
5.9
20.9
37
63
C01DA14
ATC
isosorbide mononitrate; oral
1.4
20.8
1035
7808
A02BC03
ATC
lansoprazole; oral
1.4
20.7
1060
8039
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
5.4
20.7
40
74
348
Kela drug reimbursment
Roflumilast
8.7
20.6
26
30
N02AA01
ATC
morphine; systemic, rectal
2.5
20.5
126
507
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
20.4
1392
11093
L08
ICPC
Shoulder symptom/complaint
1.5
20.2
775
5558
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
20.2
1011
7632
J96.9
ICD-10 Finland
Respiratory failure, unspecified
27.2
20.0
27
10
J45.8
ICD-10 Finland
Mixed asthma
2.6
19.8
114
445
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
19.5
1350
10760
R03AL04
ATC
indacaterol and glycopyrronium bromide; inhalant
4.9
19.4
42
86
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
2.9
19.1
92
327
J20
ICD-10 Finland
Acute bronchitis
1.8
18.9
317
1860
N02AX02
ATC
tramadol; systemic, rectal
1.4
18.8
1632
13462
A98
ICPC
Health maint/preventive medicine
1.5
18.8
3379
31310
J98.6
ICD-10 Finland
Disorders of diaphragm
70.2
18.7
21
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
18.6
1461
11861
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
18.5
529
3557
I50.0
ICD-10 Finland
Congestive heart failure
1.6
18.4
476
3129
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
18.3
1356
10902
9050/3-C38.4
ICD-O-3
Mesothelioma, malignant of pleura, NOS
19.4
18.2
27
14
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.9
18.1
218
1153
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
18.0
998
7643
SPAT1260
SPAT
Consultation of another employee
1.5
17.8
663
4715
SPAT1059
SPAT
Spirometry at the office
1.9
17.6
209
1101
L01CA04
ATC
vinorelbine; systemic
4.4
17.5
44
102
284
Kela drug reimbursment
Nintedanib and pirfenidone
4.2
17.4
45
107
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
17.3
386
2446
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
17.2
1715
14386
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
17.1
475
3170
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
17.1
1049
8164
R03AC12
ATC
salmeterol; inhalant
2.0
17.0
189
972
Y96.0
ICD-10 Finland
Work-related condition
6.6
17.0
27
41
GAA31
NOMESCO Finland
Thoracoscopy
7.5
17.0
24
32
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
16.9
1125
8867
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
16.9
1329
10752
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
16.9
137
625
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
16.9
595
4181
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
2.8
16.8
82
294
J01FA09
ATC
clarithromycin; systemic
1.4
16.8
804
5993
SPAT1254
SPAT
Administration of medicine
1.5
16.5
630
4498
JN4AD
NOMESCO Finland
Body CT examination
1.5
16.5
539
3729
L03
ICPC
Low back symptom/complaint
1.4
16.2
820
6168
A02BC01
ATC
omeprazole; systemic
1.4
15.7
1023
8016
C10AA01
ATC
simvastatin; oral
1.3
15.7
2100
18266
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
3.9
15.7
46
120
51101
ICD-8 Finland
Pleurisy, Adhaesiones pleurae
+∞
15.6
15
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
3.6
15.6
50
139
J93.8
ICD-10 Finland
Other pneumothorax
160.6
15.5
16
*
R06AE07
ATC
cetirizine; oral
1.4
15.4
1104
8783
J01FA15
ATC
telithromycin; oral
1.8
15.2
253
1480
SPAT1257
SPAT
Teaching of medicine inhalation technique
2.1
15.1
149
734
8070/3-C34.3
ICD-O-3
Squamous cell carcinoma, NOS, of lower lobe, lung
4.3
15.0
38
89
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
14.9
671
4934
G04CA02
ATC
tamsulosin; oral
1.3
14.8
1848
15875
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.8
14.7
207
1152
Z51.5
ICD-10 Finland
Palliative care
1.5
14.7
471
3239
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
14.7
1191
9637
GX2D5
NOMESCO Finland
Sleep oximetry
5.7
14.6
27
48
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
14.5
106
463
M79.6
ICD-10 Finland
Pain in limb
1.3
14.4
1334
10989
N03AX16
ATC
[U] pregabalin
1.4
14.4
738
5551
J98.4
ICD-10 Finland
Other disorders of lung
27.3
14.3
19
7
R01AD12
ATC
fluticasone furoate; nasal
1.4
14.2
643
4729
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
14.1
1072
8577
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
5.7
14.1
26
46
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
14.1
852
6583
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
14.1
1200
9767
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
14.0
619
4532
F1246, ,
NOMESCO Finland
10.9
14.0
26
24
N06AX11
ATC
mirtazapine; oral
1.3
14.0
1022
8132
SPAT1043
SPAT
Audiometry
1.5
13.9
487
3412
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
13.9
956
7538
A06AH03
ATC
naloxegol; oral
2.8
13.8
69
251
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
13.7
1260
10355
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
13.7
502
3548
M01AH05
ATC
etoricoxib; oral
1.3
13.6
1723
14773
S18
ICPC
Laceration/cut
1.3
13.6
1836
15873
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
4.8
13.5
30
63
C10AA05
ATC
atorvastatin; oral
1.3
13.4
1883
16351
WX725
NOMESCO Finland
Noninvasive ventilation
1.8
13.4
184
1018
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
4.5
13.3
32
72
L01EX09
ATC
nintedanib; oral
5.1
13.1
27
53
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
12.9
312
2013
R03AL05
ATC
formoterol and aclidinium bromide; inhalant
5.3
12.8
25
47
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
12.7
933
7411
R03BB06
ATC
glycopyrronium bromide; inhalant
4.4
12.6
31
71
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
12.6
291
1859
E0000UV, ,
ATC
1.3
12.6
1307
10892
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
12.5
2031
17892
J94.1
ICD-10 Finland
Fibrothorax
+∞
12.5
12
*
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
12.4
744
5732
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
12.3
586
4340
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
12.3
499
3592
GX2C5
NOMESCO Finland
Short-lasting oximetry
5.4
12.3
24
45
M01AC06
ATC
meloxicam; systemic, rectal
1.3
12.3
1056
8575
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
12.3
753
5819
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
9.0
12.2
25
28
M01AB05
ATC
diclofenac; systemic, rectal
1.3
12.2
2062
18231
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
12.2
237
1449
5010A
ICD-9 Finland
Asbestosis[ASBESTOSIS]
15.9
12.1
19
12
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
2.7
12.1
61
224
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
12.0
855
6754
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
3.0
12.0
51
170
207
Kela drug reimbursment
Chronic arrhythmias
1.3
11.9
882
7004
WX721
NOMESCO Finland
Oxygen concentrator therapy
13.4
11.9
20
15
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
2.5
11.9
71
284
H02AB04
ATC
methylprednisolone; systemic
1.5
11.8
439
3106
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
11.8
2214
19782
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
11.8
1249
10412
L01
ICPC
Neck symptom/complaint
1.5
11.8
397
2756
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
11.7
2870
26484
R01AD58
ATC
fluticasone, combinations; nasal
1.5
11.7
444
3156
N07BA03
ATC
varenicline; oral
2.2
11.7
96
442
R63.4
ICD-10 Finland
Abnormal weight loss
1.8
11.7
183
1054
J62.0
ICD-10 Finland
Pneumoconiosis due to talc dust
22.9
11.6
16
7
R03BB05
ATC
aclidinium bromide; inhalant
5.3
11.5
23
44
SPAT1053
SPAT
Memory test
1.3
11.5
826
6528
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
+∞
11.5
11
*
GAC30
NOMESCO Finland
Artificial pneumothorax
+∞
11.5
11
*
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.0
11.4
124
635
A07EC01
ATC
sulfasalazine; oral, rectal
1.7
11.4
222
1359
GD1AA, ,
SPAT
1.6
11.4
308
2042
XQ800
NOMESCO Finland
Prick test
2.0
11.3
124
637
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.4
11.2
457
3291
AA1AD
NOMESCO Finland
CT of head and brain
1.3
11.2
1286
10821
P01BA02
ATC
hydroxychloroquine; oral
1.7
11.1
189
1115
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
8.6
11.0
23
27
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.7
11.0
56
207
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.4
10.9
427
3053
GX1D5
NOMESCO Finland
Flow volume spirometry
5.4
10.9
21
39
M01AE02
ATC
naproxen; oral, rectal
1.3
10.9
1615
13997
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
10.8
622
4750
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
10.8
150
834
WPB10
NOMESCO Finland
Making a convalescent care decision
3.8
10.6
31
81
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
10.6
110
554
R78
ICPC
Acute bronchitis/bronchiolitis
2.3
10.6
75
325
XF402
NOMESCO Finland
ECG with work load test
1.4
10.5
449
3262
R81
ICPC
Pneumonia
1.8
10.5
155
879
51120
ICD-8 Finland
Pleurisy, Other specified forms of effusion, except tuberculous
+∞
10.4
10
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
10.4
1347
11470
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
10.3
526
3941
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
3.3
10.2
38
117
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
10.2
158
907
AN1
HP
Coronary angiography
1.4
10.1
606
4657
XX3DW
NOMESCO Finland
Time consuming IT work
1.4
10.1
412
2968
XX2RW, ,
NOMESCO Finland
2.6
10.0
58
229
9052/3-C38.4
ICD-O-3
Epithelioid mesothelioma, malignant of pleura, NOS
40.2
10.0
12
*
R74
ICPC
Upper respiratory infection acute
1.4
10.0
544
4117
R42
ICD-10 Finland
Dizziness and giddiness
1.3
9.9
876
7108
R06AX27
ATC
desloratadine; oral
1.4
9.9
525
3956
D07AC13
ATC
mometasone; topical
1.3
9.8
911
7436
RS150, ,
NOMESCO Finland
26.1
9.8
13
5
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
9.8
439
3214
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
4.5
9.8
23
51
XKD00
NOMESCO Finland
Uroflowmetry
1.3
9.8
1094
9145
R07.3
ICD-10 Finland
Other chest pain
1.5
9.5
343
2413
L04AX05
ATC
pirfenidone; oral
3.8
9.5
28
74
J94.2
ICD-10 Finland
Haemothorax
30.1
9.4
12
*
H25.8
ICD-10 Finland
Other senile cataract
1.4
9.4
553
4234
SPAT1211
SPAT
Application of soft bandage
1.5
9.3
309
2141
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
2.6
9.2
52
203
I50
ICD-10 Finland
Heart failure
1.7
9.2
168
1013
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
7.7
9.1
20
26
R03DX07
ATC
roflumilast; oral
7.7
9.1
20
26
R05FB02
ATC
cough suppressants and expectorants; systemic
1.2
9.1
1237
10559
M02AA07
ATC
piroxicam; topical
1.2
8.9
1172
9958
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
2.7
8.9
45
166
SPAT1216
SPAT
Assessment of functional ability
1.3
8.9
674
5349
N03AX12
ATC
[U] gabapentin; oral
1.4
8.9
483
3649
J01FA10
ATC
azithromycin; systemic
1.2
8.9
1326
11425
R13
ICD-10 Finland
Dysphagia
1.5
8.9
272
1853
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.8
1082
9121
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
6.8
8.8
21
31
UJF32
NOMESCO Finland
Coloscopy
1.3
8.8
1007
8420
C09CA06
ATC
candesartan; oral
1.3
8.8
726
5828
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
8.8
1747
15509
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
8.8
2043
18426
WPA13
NOMESCO Finland
Palliative consultation
3.8
8.8
26
69
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
8.7
2669
24744
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.7
1183
10084
B01AC04
ATC
clopidogrel; oral
1.3
8.7
898
7414
H02AB07
ATC
prednisone; oral
1.4
8.7
443
3312
SPAT1262
SPAT
Handing over of treatment supplies
1.3
8.7
728
5854
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
8.7
755
6101
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
8.7
471
3558
M25.5
ICD-10 Finland
Pain in joint
1.3
8.6
776
6297
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
1.7
8.6
157
945
1240
FHL
Bronchoscopy
2.4
8.6
56
234
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.3
8.6
592
4633
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.4
8.6
454
3415
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
8.6
634
5013
A02BA02
ATC
ranitidine; systemic
1.3
8.5
713
5731
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
9.0
8.5
17
19
R01AD08
ATC
fluticasone; nasal
1.3
8.5
674
5381
R84
ICPC
Malignant neoplasm bronchus/lung
3.7
8.4
26
71
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
2.8
8.4
40
143
J01DA01
ATC
[U] cefalexin
1.2
8.4
2013
18173
L17
ICPC
Foot/toe symptom/complaint
1.3
8.4
999
8384
J01FF01
ATC
clindamycin; systemic
1.3
8.4
844
6945
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.2
8.4
1091
9253
D07AC01
ATC
betamethasone; topical
1.2
8.3
1214
10418
51299
ICD-8 Finland
Spontaneous pneumothorax
+∞
8.3
8
*
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.3
8.3
63
282
L04AA13
ATC
[U] leflunomide
2.4
8.3
54
226
J62.8
ICD-10 Finland
Pneumoconiosis due to other dust containing silica
10.7
8.3
15
14
UDC00
NOMESCO Finland
Ear microscopy
1.5
8.2
264
1815
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
1.9
8.2
95
499
R53
ICD-10 Finland
Malaise and fatigue
1.3
8.2
840
6928
F2680, ,
NOMESCO Finland
8.1
8.1
17
21
J98.9
ICD-10 Finland
Respiratory disorder, unspecified
17.2
8.1
12
7
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.6
8.1
166
1033
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
8.0
322
2310
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
8.9
8.0
16
18
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.4
8.0
374
2758
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
2.7
8.0
41
153
UKC02
NOMESCO Finland
Cystoscopy
1.3
8.0
923
7717
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.9
1738
15529
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
7.8
719
5848
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
8.4
7.8
16
19
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
3.3
7.8
28
85
SPAT1283
SPAT
Restricted health certificate
1.7
7.7
142
858
R09.1
ICD-10 Finland
Pleurisy
2.3
7.7
53
228
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
2.8
7.7
38
139
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.7
591
4696
M48.0
ICD-10 Finland
Spinal stenosis
1.3
7.7
518
4043
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.7
7.6
142
861
SPAT1104
SPAT
Monitoring of emergency patient
1.5
7.6
240
1646
H13
ICPC
Plugged feeling ear
1.3
7.6
852
7096
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
7.5
1173
10115
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
1.9
7.5
90
479
H25.1
ICD-10 Finland
Senile nuclear cataract
1.2
7.5
1395
12249
GD2SN
NOMESCO Finland
Lung ventilation SPECT
3.0
7.5
31
103
8140/3-C34.3
ICD-O-3
Adenocarcinoma, NOS, of lower lobe, lung
3.9
7.4
21
54
GAC37
NOMESCO Finland
Endoscopic chemical pleurodesis
80.2
7.4
8
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.3
7.4
528
4151
D82
ICPC
Teeth/gum disease
1.2
7.3
863
7222
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.5
7.3
198
1315
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
1.9
7.3
88
470
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.5
7.3
206
1381
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
6.8
7.3
17
25
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
7.2
755
6228
R01
ICPC
Pain respiratory system
2.5
7.2
44
179
R04.0
ICD-10 Finland
Epistaxis
1.4
7.2
344
2544
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
4.3
7.2
18
42
51998
ICD-8 Finland
Other diseases of respiratory system, Alii definiti
30.1
7.1
9
*
SPAT1060
SPAT
Administration of oxygen
3.3
7.1
25
75
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
1.8
7.1
107
613
H83.3
ICD-10 Finland
Noise effects on inner ear
2.1
7.1
60
282
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.0
438
3378
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.5
7.0
182
1198
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.3
6.9
394
2996
D07XC01
ATC
betamethasone; topical
1.3
6.9
425
3269
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.9
621
5030
M01AX17
ATC
nimesulide; oral
1.2
6.9
778
6475
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.3
6.9
400
3053
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.4
6.8
346
2584
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
1.8
6.8
96
539
J86.9
ICD-10 Finland
Pyothorax without fistula
2.6
6.8
36
137
A07AA02
ATC
nystatin; oral
1.5
6.8
182
1207
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.6
6.8
166
1079
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.4
6.7
274
1976
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.4
6.7
317
2344
M01AH02
ATC
rofecoxib; oral
1.3
6.7
414
3192
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.4
6.6
336
2511
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.6
6.6
163
1061
N02AA05
ATC
oxycodone; systemic
1.2
6.6
805
6754
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
6.6
1500
13375
I95.1
ICD-10 Finland
Orthostatic hypotension
1.5
6.6
213
1469
-31
ICPC
Medical examin/health eval partial
1.5
6.6
232
1627
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.0
6.5
67
339
I48.2
ICD-10 Finland
Chronic atrial fibrillation
1.4
6.5
256
1831
E000001, ,
ATC
1.3
6.5
546
4381
ZXD00
NOMESCO Finland
Emergency procedure
1.7
6.5
117
704
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.5
399
3068
R04
ICPC
Breathing problem other
1.7
6.5
118
712
M54
ICD-10 Finland
Dorsalgia
1.4
6.5
264
1900
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
6.5
292
2139
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
6.2
6.5
16
26
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
1.5
6.4
219
1530
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
6.3
601
4899
I20.09
ICD-10 Finland
Unstable angina
1.4
6.3
283
2074
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.5
6.3
186
1261
A06AC01
ATC
ispaghula (psylla seeds); oral
1.2
6.3
836
7076
J60
ICD-10 Finland
Coalworker pneumoconiosis
+∞
6.2
6
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
2.2
6.2
49
224
H04.10
ICD-10 Finland
Dry eye syndrome
1.4
6.2
266
1935
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.4
6.2
254
1833
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
5.0
6.2
18
36
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.4
6.1
270
1973
GD2AT
NOMESCO Finland
Cytology of the lungs with ultrasound guidance
4.1
6.1
16
39
GAC46
NOMESCO Finland
Partial decortication of pleura
8.6
6.0
12
14
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
3.1
6.0
24
78
R09.3
ICD-10 Finland
Abnormal sputum
2.2
6.0
48
221
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
6.0
206
1438
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
1.7
6.0
95
553
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
1.8
6.0
78
428
PD5AD
NOMESCO Finland
CT of aorta
1.7
6.0
113
690

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
162
138
12.19
160.41
1.4
1.1
13.96
15.05
u/l
0.16
152
108
89
31
29.34
133.67
1.5
1.1
47.47
37.80
ug/l
0.11
54
12
211
381
5.79
111.89
1.5
1.2
35.46
26.65
g/l
16.55
199
306
237
516
4.82
101.67
3.0
2.7
—
—
—
0
0
159
251
6.55
96.48
1.6
1.2
—
—
—
0
0
163
280
6.03
90.91
1.4
1.2
—
—
—
0
0
662
2941
2.50
89.95
4.6
3.4
5.30
5.02
kpa
12.54
628
2760
645
2862
2.49
87.71
4.5
3.4
7.42
7.42
ph
0.09
532
2366
2407
17501
1.94
86.85
6.1
5.8
0.21
0.21
e9/l
0.05
2157
14816
180
362
5.16
84.62
1.4
1.2
3499.47
3392.14
e6/l
0.02
152
235
2343
16996
1.91
83.84
6.0
5.6
0.68
0.65
e9/l
6.44
2057
14162
2351
17084
1.91
83.55
6.0
5.6
0.04
0.04
e9/l
1.20
2070
14259
2357
17327
1.87
78.71
6.0
5.7
1.81
1.86
e9/l
0.58
2121
14807
73
56
13.26
76.82
1.4
1.1
4.08
3.34
mmol/l
0.57
68
48
1762
11959
1.84
74.75
6.1
5.7
—
—
—
0
0
156
316
5.10
72.69
1.4
1.2
141333.12
19826.09
e6/l
2.42
98
165
197
491
4.17
70.96
2.5
2.4
—
—
—
0
0
97
130
7.62
68.30
1.2
1.1
7.36
7.43
ph
1.19
81
80
2142
15844
1.75
64.47
6.6
6.0
9.60
9.37
%
2.39
2002
14632
2157
16000
1.75
64.15
6.4
6.0
23.94
24.83
%
3.26
2038
14970
461
2014
2.46
63.70
4.8
3.6
—
—
—
0
0
2132
15807
1.74
63.10
6.5
5.9
2.85
2.90
%
0.52
1995
14591
128
251
5.23
61.86
1.3
1.2
5.86
7.08
mmol/l
3.83
122
231
2128
15831
1.73
61.64
6.6
6.0
0.63
0.62
%
0.30
1994
14632
2447
19043
1.73
59.08
8.2
8.8
4.64
4.51
e9/l
1.35
2180
16224
2904
23799
1.79
57.55
6.0
4.4
16.51
14.32
mm/h
8.88
2692
21803
1954
14439
1.69
55.95
4.1
3.4
1688.28
1955.98
ng/l
2.41
1738
12756
2084
15666
1.69
55.89
6.3
5.9
60.20
59.38
%
2.43
1989
14789
329
1337
2.59
52.66
1.3
1.3
316.88
333.07
u/ml
0.08
306
1212
256
917
2.91
52.28
3.9
3.4
—
—
—
0
0
2036
15413
1.65
51.47
5.7
4.5
49.00
87.37
ng/l
2.25
1769
12833
354
1542
2.42
48.78
5.1
3.7
25.20
24.49
mmol/l
4.15
324
1373
998
6363
1.76
47.42
5.4
4.8
—
—
—
0
0
2491
20066
1.63
47.26
23.3
21.8
1.41
1.41
inr
0.16
2159
17136
359
1596
2.37
47.21
3.3
2.7
25.36
24.16
mmol/l
6.45
351
1564
57
64
9.02
46.34
1.4
1.3
3.67
3.00
%
0.15
50
52
601
3353
1.93
43.65
1.3
1.3
432.05
414.56
titre
0.11
166
712
2380
19164
1.59
43.38
6.7
6.7
12.92
13.48
umol/l
0.99
2254
18301
120
299
4.11
43.20
1.4
1.2
—
—
—
0
0
63
90
7.10
41.92
1.4
1.2
73.61
59.66
%
1.89
56
66
209
783
2.76
39.15
4.7
3.8
5.02
4.86
kpa
1.89
203
762
209
783
2.76
39.15
4.7
3.8
2.57
2.33
mmol/l
0.67
149
493
209
786
2.75
38.86
4.7
3.8
8.11
8.45
kpa
2.30
203
764
830
5286
1.72
38.51
6.1
6.7
1.61
0.59
mmol/l
9.68
691
4208
694
4225
1.78
37.68
1.3
1.3
46.70
38.69
iu/ml
0.43
217
1171
1530
11386
1.55
37.49
3.0
2.7
59.52
69.22
u/l
0.74
1402
10535
3019
26109
1.63
37.48
9.4
8.5
83.83
83.25
u/l
0.20
2865
24655
2184
17581
1.53
37.14
7.1
6.7
1.20
1.20
mmol/l
0.39
1978
16099
831
5350
1.70
36.86
6.2
6.8
5.17
4.95
kpa
6.81
799
5126
485
2660
1.94
36.68
4.5
4.1
—
—
—
0
0
830
5349
1.70
36.65
6.2
6.8
10.76
11.96
kpa
12.34
804
5120
2379
19576
1.53
35.99
7.5
7.5
1.20
1.20
mmol/l
1.05
1928
16802
823
5324
1.69
35.72
6.2
6.8
7.42
7.42
ph
1.79
562
2891
640
3860
1.78
35.71
2.2
2.7
66.80
66.01
g/l
1.84
575
3470
206
810
2.63
35.08
1.2
1.1
0.29
0.28
u/ml
0.09
17
70
752
4856
1.67
32.52
6.2
6.9
94.51
95.42
%
3.33
734
4679
639
3953
1.73
32.38
1.2
1.2
11.55
15.40
u/ml
0.53
198
1290
2200
18051
1.48
31.93
3.9
3.3
61.58
59.95
u/l
0.23
1975
16417
260
1233
2.19
29.06
4.4
3.4
7.41
7.41
ph
1.10
254
1215
379
2065
1.92
28.96
1.8
1.8
1.33
2.59
ug/l
2.24
332
1793
224
1003
2.31
28.76
1.6
1.4
8.54
6.24
iu/ml
0.59
64
220
1381
10485
1.48
28.71
4.6
4.2
0.00
0.00
estimate
0.96
499
3336
486
2877
1.78
28.48
6.5
6.2
24.90
23.95
mmol/l
6.91
474
2748
180
739
2.50
28.03
1.6
1.7
11.80
13.84
mg/l
1.45
164
674
2578
22133
1.46
27.55
6.0
5.3
6.88
6.99
mmol/l
1.86
2485
21159
226
1050
2.22
26.56
2.4
2.1
130.25
127.36
g/l
0.84
158
818
3342
30361
1.60
26.37
25.9
20.8
28.57
31.09
mg/l
3.93
3046
26290
520
3211
1.71
26.14
4.1
4.1
0.28
0.23
%
0.08
149
930
139
524
2.71
25.75
2.6
2.2
0.96
-0.24
mmol/l
2.61
127
500
677
4496
1.61
25.59
5.9
5.5
33.58
33.23
%
0.32
438
2877
49
90
5.50
25.52
1.6
1.8
—
—
—
0
0
1629
12982
1.43
25.33
4.7
4.5
—
—
—
0
0
516
3209
1.70
25.22
3.9
4.0
0.16
0.12
%
0.58
152
978
533
3379
1.67
24.16
4.0
4.0
1.12
0.90
%
0.72
172
1139
506
3178
1.68
23.75
3.9
3.9
0.61
0.70
%
0.59
169
1060
256
1313
2.01
23.22
1.2
1.2
—
—
—
0
0
148
607
2.49
23.13
3.0
3.1
59.39
59.48
%
0.03
148
607
1627
13115
1.40
23.02
4.6
4.3
2.06
0.13
estimate
0.73
486
3242
2512
21836
1.40
22.42
4.0
3.6
15.43
15.11
pmol/l
7.95
2170
19317
921
6721
1.48
22.28
1.6
1.6
1.51
1.78
mg/l
1.28
744
5362
2653
23291
1.41
22.26
5.8
5.1
725.44
1323.28
e6/l
0.44
50
426
119
453
2.68
21.67
2.1
1.8
87.77
89.19
%
1.29
119
448
3055
27572
1.45
21.46
5.3
4.8
2.10
2.12
mu/l
0.35
2663
24649
581
3890
1.58
20.89
4.7
4.5
7.35
7.36
ph
0.06
429
2784
67
186
3.65
20.85
1.1
1.1
—
—
—
0
0
1109
8481
1.42
20.68
1.9
1.8
418.35
21492470.56
pmol/l
4.79
839
6863
484
3112
1.63
20.58
3.7
4.0
1.21
1.22
mmol/l
2.85
412
2659
1104
8457
1.42
20.33
2.0
1.8
1180.21
1125.03
nmol/l
1.12
778
6332
427
2674
1.67
20.12
2.4
2.3
368.28
384.47
nmol/l
0.79
392
2443
35
59
5.98
19.94
1.3
1.1
1.51
1.27
mmol/l
0.34
27
21
1140
8834
1.41
19.50
4.0
3.8
0.59
0.24
estimate
0.27
450
2958
2072
17681
1.35
19.34
4.4
4.1
0.00
0.00
estimate
0.64
564
3898
2096
17921
1.35
19.30
4.5
4.1
0.01
3.97
estimate
2.92
573
3997
148
660
2.29
19.22
1.2
1.1
57.19
43.76
u/ml
—
9
18
2103
18006
1.35
19.10
4.6
4.1
0.02
0.37
estimate
0.67
524
3650
29
44
6.63
18.29
1.2
1.1
0.34
2.86
mmol/l
0.57
23
18
141
633
2.27
18.05
1.3
1.1
22.94
3.06
u/ml
0.50
15
52
643
4554
1.49
17.61
10.3
8.8
—
—
—
0
0
140
635
2.25
17.49
1.3
1.2
5.80
5.50
u/ml
0.03
17
79
583
4053
1.51
17.46
3.1
3.2
5.26
5.11
e9/l
0.12
457
3323
92
346
2.70
17.22
1.2
1.2
—
—
—
0
0
3409
31773
1.48
17.16
31.4
26.6
4.07
4.04
mmol/l
11.21
3325
31071
2024
17392
1.33
17.15
5.2
5.3
33.59
34.37
g/l
7.26
1855
16158
3406
31754
1.47
16.97
31.3
26.3
139.21
139.61
mmol/l
13.37
3330
31083
53
145
3.69
16.90
1.3
1.4
3.47
2.21
u/ml
0.23
32
91
3367
31347
1.46
16.65
15.4
13.3
24.74
25.49
u/l
0.98
3237
30096
132
601
2.24
16.36
1.3
1.3
—
9.95
—
0
15
27
19
14.30
16.29
1.3
1.2
13.71
25.50
%
0.80
21
14
369
2351
1.63
16.15
2.6
2.7
11.40
10.83
g/l
1.38
333
2147
3418
31954
1.46
16.14
34.6
28.9
92.55
93.05
umol/l
0.29
3361
31446
625
4473
1.47
16.13
6.9
7.5
124.90
119.90
g/l
7.44
612
4368
1721
14539
1.32
16.03
3.2
3.2
185.43
178.57
ug/l
0.33
1503
13153
1484
12298
1.33
15.75
2.4
2.3
210.79
238.69
u/l
0.62
1377
11582
332
2076
1.65
15.65
4.7
4.3
36.91
36.91
°c
0.13
326
2052
3416
31990
1.45
15.42
38.4
31.9
234.08
226.26
e9/l
9.39
3327
31114
3416
31991
1.45
15.40
38.3
31.8
92.49
92.22
fl
2.65
3353
31470
3416
31991
1.45
15.40
38.2
31.7
30.64
30.66
pg
0.15
3354
31470
3416
31991
1.45
15.40
38.3
31.8
4.36
4.38
e12/l
1.80
3304
30976
3416
31992
1.45
15.39
39.0
32.4
39.77
39.64
%
0.65
3354
31446
3416
31995
1.45
15.36
38.7
32.1
132.28
133.10
g/l
2.20
3352
31480
3416
31998
1.45
15.32
38.4
31.9
7.41
7.11
e9/l
7.01
3311
30986
71
249
2.88
15.19
1.3
1.3
7.31
7.06
g/l
0.21
46
186
71
249
2.88
15.19
1.3
1.3
2.95
3.08
g/l
0.23
47
188
71
249
2.88
15.19
1.3
1.3
0.50
0.46
g/l
0.35
49
185
70
245
2.89
15.04
1.3
1.3
—
—
—
0
0
851
6532
1.38
14.74
3.1
3.0
0.81
0.81
mmol/l
0.22
791
6118
406
2711
1.55
14.53
7.0
7.2
25.14
24.35
mmol/l
3.17
400
2690
3199
29715
1.37
14.28
6.8
6.6
2.30
2.34
mmol/l
1.40
2776
26908
295
1854
1.64
13.62
1.8
2.0
1.18
1.44
g/l
0.76
265
1662
3177
29545
1.36
13.55
6.6
6.1
6.16
6.22
mmol/l
2.27
2744
26339
2993
27588
1.33
13.55
5.0
4.7
1.24
1.24
mmol/l
0.20
2552
24518
1365
11356
1.31
13.54
2.5
2.4
3.06
2.90
mg/l
1.70
1137
9631
1488
12527
1.30
13.48
2.9
3.5
2.34
2.34
mmol/l
0.14
1332
11209
719
5441
1.39
13.43
1.9
2.0
—
—
—
0
0
3091
28654
1.34
13.25
6.0
5.6
1.34
1.34
mmol/l
0.14
2661
25796
3117
28933
1.34
13.23
6.0
5.7
4.09
4.12
mmol/l
1.15
2718
26275
402
2759
1.51
12.63
7.0
8.2
25.04
23.89
mmol/l
8.33
389
2683
3121
29048
1.33
12.48
8.3
8.0
41.07
41.08
mmol/mol
0.02
2748
26543
904
7189
1.33
12.15
2.7
2.7
2.21
2.20
g/l
0.36
791
6598
1226
10178
1.29
12.02
3.5
3.3
376.02
372.97
umol/l
0.44
976
8680
25
29
8.67
11.98
1.3
1.2
3.47
5.36
%
0.49
15
14
94
427
2.23
11.82
1.4
1.7
0.87
1.06
g/l
0.80
68
336
1614
13910
1.27
11.62
2.4
2.2
77.79
78.34
nmol/l
0.31
1353
12047
184
1070
1.75
11.36
1.3
1.4
31.94
11.75
iu/ml
—
5
16
1475
12604
1.27
11.31
1.9
1.8
19.72
19.23
nmol/l
0.26
1187
10629
139
744
1.90
11.24
1.7
1.3
0.24
0.24
g/l
0.16
132
710
2582
23568
1.27
11.20
6.7
6.6
3.46
4.37
ug/l
0.98
2236
21032
940
7599
1.31
11.10
2.7
2.8
11.88
12.15
umol/l
0.44
836
7013
143
776
1.87
11.09
1.8
1.3
1.10
1.18
g/l
1.99
135
742
1648
14308
1.26
10.93
4.0
3.6
6.26
6.26
ph
0.05
934
7663
1368
11631
1.27
10.82
4.4
4.3
7.39
7.40
ph
0.57
1040
8451
62
246
2.54
10.57
2.4
2.0
16.55
15.73
%
1.02
62
246
838
6728
1.31
10.31
2.7
2.8
21.79
22.20
%
0.36
751
6217
609
4674
1.36
10.21
1.3
1.3
—
—
—
0
0
209
1300
1.64
10.09
5.5
5.4
1.34
1.40
mmol/l
0.47
192
1162
32
90
3.58
9.91
1.0
1.1
—
—
—
0
0
32
90
3.58
9.91
1.0
1.1
—
—
—
0
0
32
90
3.58
9.91
1.0
1.1
—
—
—
0
0
518
3898
1.38
9.82
1.5
1.4
—
—
—
0
0
622
4835
1.34
9.55
1.6
1.6
3.22
2.86
g/l
2.11
376
2723
628
4899
1.33
9.40
2.3
2.5
67.97
66.08
e9/l
0.69
490
3692
105
545
1.95
9.36
2.3
2.1
32.09
24.41
mg/l
0.63
35
187
1481
12873
1.24
9.26
2.5
2.4
—
—
—
0
0
92
460
2.02
9.13
1.7
1.3
—
—
—
0
0
92
460
2.02
9.13
1.7
1.3
—
—
—
0
0
92
460
2.02
9.13
1.7
1.3
—
—
—
0
0
92
460
2.02
9.13
1.7
1.3
—
—
—
0
0
231
1524
1.55
8.74
3.9
3.6
1.36
1.50
mmol/l
0.95
226
1498
704
5650
1.30
8.53
5.1
6.0
1.04
1.03
mmol/l
0.12
642
5257
510
3926
1.34
8.31
4.0
3.0
197.12
262.10
ng/l
4.36
480
3653
405
3016
1.38
8.15
1.4
1.3
—
—
—
0
0
151
926
1.66
7.78
5.7
6.2
104.68
105.31
mmol/l
0.97
143
828
151
926
1.66
7.78
5.7
6.2
11.32
11.57
mmol/l
0.48
143
828
175
1117
1.59
7.68
3.4
3.2
0.81
0.80
nmol/l
0.11
136
892
2130
23145
0.83
7.64
34.2
28.6
331.33
331.98
g/l
2.75
2115
22955
59
267
2.23
7.62
1.2
1.2
—
—
—
0
0
563
4456
1.31
7.52
3.0
4.4
17.54
22.35
ug/l
0.29
493
3785
1970
17871
1.20
7.45
2.4
2.4
94.51
91.29
pmol/l
2.23
1118
10231
654
5285
1.28
7.45
1.2
1.2
1.75
2.00
u/ml
0.18
155
1260
56
257
2.20
7.02
1.4
1.1
106.26
49.57
u/ml
—
7
7
174
1136
1.56
6.96
1.5
1.6
—
—
—
0
0
170
1116
1.55
6.65
1.4
1.4
—
—
—
0
0
87
479
1.83
6.60
4.0
3.5
57.70
59.27
%
0.26
73
401
471
3708
1.31
6.52
2.3
2.1
0.18
0.19
g/l
2.72
423
3408
33
123
2.70
6.49
1.1
1.0
—
—
—
0
0
256
1842
1.42
6.33
2.7
3.4
45.17
57.69
mg/l
0.85
202
1577
949
8140
1.22
6.25
4.2
4.0
—
—
—
0
0
1118
9751
1.20
6.18
3.3
2.9
3.20
3.30
e6/l
0.17
1036
8913
255
1845
1.41
6.12
2.7
3.4
57.75
63.59
mg/l
0.38
201
1576
1599
14410
1.18
6.08
16.2
12.8
0.00
0.00
e9/l
0.62
1362
11656
518
4167
1.28
6.07
3.0
2.4
6.23
7.05
ug/l
0.61
440
3639
82
456
1.81
6.06
1.4
1.5
65.38
66.69
%
0.11
48
286
88
500
1.78
6.06
2.3
2.7
—
—
—
0
0
19
54
3.53
5.87
1.0
1.1
—
—
—
0
0
369
2852
1.32
5.84
2.0
2.2
160.62
185.40
ug/g
0.68
263
2237
498
4028
1.27
5.58
6.6
6.8
1.38
1.41
mmol/l
0.21
491
3932
117
738
1.60
5.50
4.3
3.5
1.34
1.73
%
0.50
105
643
290
2185
1.35
5.46
4.6
4.8
1.68
1.56
%
1.75
278
2070
103
1635
0.62
5.46
2.8
3.5
184.30
2821.73
u/ml
0.98
86
1414
39
173
2.27
5.38
1.4
1.4
3.70
3.51
%
—
10
37
1161
10271
1.18
5.33
3.5
3.2
36.98
38.21
u/l
0.18
1066
9597
74
416
1.79
5.32
1.3
1.1
63.97
35.37
u/ml
—
6
29
729
6182
1.22
5.30
2.4
2.4
1.78
1.73
%
0.84
615
5419
91
544
1.69
5.28
1.5
1.2
—
—
—
0
0
1799
16494
1.16
5.27
3.0
3.0
—
—
estimate
—
0
0
539
4430
1.25
5.26
5.9
6.6
11.45
11.83
mmol/l
0.53
503
4192
78
448
1.76
5.23
1.2
1.1
—
13.12
u/ml
—
0
5
226
1655
1.39
5.10
2.7
3.3
3.62
4.93
ratio
0.21
129
982
62
336
1.86
5.03
1.1
1.2
—
—
—
0
0
33
141
2.35
4.98
1.0
1.1
1.37
2.15
u/ml
—
10
72
264
1995
1.35
4.90
4.8
5.0
0.88
0.86
%
0.57
251
1886
366
2898
1.29
4.87
3.9
4.2
97.04
106.12
ng/l
1.03
295
2479
33
143
2.32
4.84
1.0
1.1
0.70
0.79
u/ml
—
10
72
125
829
1.52
4.77
1.7
2.2
0.84
0.87
%
0.32
87
586
17
52
3.28
4.74
1.5
1.3
—
—
—
0
0
1530
13939
1.16
4.72
3.6
3.6
7.51
7.61
mmol/l
0.49
1196
11478
197
1432
1.40
4.67
2.8
3.0
2139.02
482.98
mg/l
0.45
84
654
113
739
1.54
4.61
1.4
1.3
59.55
62.37
mmol/l
0.35
94
599
38
180
2.12
4.53
1.2
1.1
1.53
1.07
u/ml
0.30
21
104
1522
13902
1.15
4.46
3.6
3.6
66.49
54.36
mg/l
1.01
973
9611
222
1659
1.36
4.46
2.1
2.1
455.69
629.43
ug/l
0.73
200
1589
378
3041
1.27
4.44
1.4
1.5
—
—
—
0
0
276
2134
1.31
4.40
2.6
2.5
—
—
—
0
0
336
2671
1.28
4.35
9.1
8.8
16.38
15.88
%
2.49
329
2574
50
266
1.89
4.35
2.1
2.0
1054.30
1067.79
e6/l
0.04
44
239
34
158
2.16
4.27
1.1
1.1
—
—
—
0
0
34
160
2.13
4.14
1.1
1.1
—
—
—
0
0
1557
14313
1.14
4.06
4.4
4.4
11.33
9.33
mg/mmol
0.79
967
9497
83
522
1.60
4.05
1.3
1.4
11.09
8.52
u/l
1.31
60
410
72
440
1.65
3.94
5.9
3.8
—
—
—
0
0
151
1087
1.40
3.85
2.3
2.6
1.77
1.86
mg/l
0.69
136
932
428
3553
1.23
3.82
2.1
2.1
0.00
0.00
estimate
-0.00
68
646
62
368
1.70
3.80
1.4
1.4
29.17
23.21
%
0.60
40
233
1313
12014
1.14
3.56
2.1
2.0
1.28
1.24
mmol/l
0.44
985
9705
1317
12057
1.14
3.54
2.6
2.8
—
—
—
0
0
232
1811
1.30
3.51
2.0
2.2
0.00
0.57
estimate
0.52
42
453
21
88
2.39
3.39
1.1
1.1
0.42
1.66
u/ml
—
9
47
24
107
2.25
3.38
2.4
1.9
31.08
34.06
%
0.40
24
107
9
18
5.01
3.37
1.3
1.4
—
—
—
0
0
145
1065
1.38
3.33
1.4
1.5
265.40
252.58
ug/g
0.34
92
684
931
8364
1.15
3.29
3.4
3.3
534.54
561.38
mosm/kgh2o
3.73
831
7368
127
917
1.40
3.24
2.2
2.3
32.30
33.87
umol/l
0.19
106
789
2408
22946
1.12
3.22
6.2
5.1
0.60
1603.94
—
5
63
606
6911
0.86
3.15
3.9
3.7
1.11
1.09
e6/l
0.03
336
3807
762
6772
1.15
3.12
1.9
1.9
30.56
30.21
s
0.69
735
6587
44
252
1.75
3.12
3.0
3.1
—
—
—
0
0
25
118
2.13
3.09
1.4
1.3
76.36
70.00
umol/l
0.08
11
72
90
617
1.47
3.06
1.1
1.2
—
—
—
0
0
142
1061
1.35
2.96
1.1
1.1
64.93
106.75
u/ml
1.33
47
314
330
2743
1.22
2.96
1.4
1.5
—
—
—
0
0
891
8060
1.14
2.80
5.1
4.4
1.02
1.02
kg/l
0.65
663
5584
200
1585
1.28
2.76
1.2
1.3
—
—
—
0
0
20
91
2.20
2.73
1.1
1.1
3.87
1.00
u/ml
—
10
52
23
111
2.08
2.72
2.4
1.9
7.74
5.64
%
0.28
23
102
276
2278
1.23
2.67
3.4
3.5
25.77
24.70
mmol/l
4.80
262
2200
39
227
1.73
2.66
1.7
2.1
130.81
133.72
ng/l
0.05
39
227
12
43
2.80
2.64
1.6
1.7
46.17
48.42
umol/l
0.13
12
43
80
554
1.45
2.63
19.5
8.8
7.81
7.64
mmol/l
0.15
67
440
448
3888
1.17
2.52
1.4
1.4
—
—
—
0
0
204
1641
1.26
2.51
1.2
1.3
—
—
—
0
0
32
179
1.79
2.51
2.1
2.0
241.04
254.94
e6/l
0.16
26
161
230
1877
1.24
2.49
1.2
1.2
—
—
—
0
0
292
2444
1.21
2.48
1.4
1.5
—
—
—
0
0
177
1407
1.27
2.42
1.3
1.3
—
—
—
0
0
21
103
2.04
2.41
1.2
1.2
89.38
4.15
u/l
—
5
22
32
182
1.76
2.39
1.7
1.7
40.15
39.71
g/l
0.14
32
182
99
727
1.37
2.37
1.1
1.2
354.29
101.67
titre
—
7
60
1221
11351
1.11
2.35
3.6
3.5
—
—
—
0
0
58
386
1.51
2.35
1.2
1.3
231.71
263.35
pmol/l
0.46
49
300
37
222
1.67
2.30
1.0
1.2
1.03
1.04
promille
0.01
27
181
31
177
1.76
2.29
1.9
2.0
553.33
515.22
e6/l
0.16
24
148
504
4457
1.15
2.23
1.8
1.9
—
—
—
0
0
47
307
1.54
2.10
1.7
1.4
—
—
—
0
0
12
49
2.45
2.10
1.0
1.2
35.85
1652.31
ng/l
—
6
36
1252
11716
1.10
2.08
4.0
3.7
0.59
0.46
e6/l
0.74
1002
9018
22
117
1.89
2.05
1.0
1.1
0.52
0.40
u/ml
0.14
11
72
2452
23662
1.09
2.04
29.4
26.4
14.20
13.99
%
10.51
2419
23311
48
318
1.52
2.03
1.4
1.3
—
—
nmol/l
—
0
0
8
26
3.08
2.01
2.9
1.2
—
—
—
0
0
225
1879
1.21
2.01
1.2
1.3
—
—
—
0
0
539
4834
1.13
1.95
4.0
3.8
6.02
5.74
kpa
6.44
527
4704
120
940
1.29
1.91
3.1
3.2
2104.97
990.41
u/ml
0.45
109
871
28
165
1.70
1.90
4.1
3.4
—
—
—
0
0
524
4704
1.13
1.87
4.0
3.8
2.47
1.49
mmol/l
7.97
456
4007
141
1134
1.25
1.82
2.3
2.3
103.28
112.98
ug/min
0.17
67
652
287
3312
0.86
1.79
3.1
2.5
38.95
39.27
u/l
0.02
232
2779
989
9216
1.10
1.77
2.6
2.7
—
—
—
0
0
5
13
3.85
1.71
1.0
1.4
—
—
—
0
0
5
13
3.85
1.71
1.2
1.2
—
—
—
0
0
126
1010
1.26
1.70
1.5
1.6
13079.42
17109.49
e6/l
0.74
93
693
103
807
1.28
1.67
1.3
1.2
—
—
—
0
0
40
268
1.50
1.65
1.3
1.5
—
1784.00
—
0
10
441
3951
1.13
1.65
8.1
8.0
—
—
—
0
0
42
285
1.48
1.64
1.1
1.1
34.93
36.35
mmol/l
0.17
35
247
18
98
1.84
1.61
1.0
1.1
—
—
—
0
0
27
166
1.63
1.61
1.2
1.1
—
—
—
0
0
539
4901
1.12
1.57
4.0
3.8
7.38
7.38
ph
0.03
347
2931
224
1920
1.18
1.56
2.2
2.3
2.80
2.91
g/l
0.92
197
1717
5
15
3.34
1.52
1.0
1.3
—
—
—
0
0
5
15
3.34
1.52
1.2
1.1
—
—
—
0
0
6
140
0.43
1.52
1.3
1.2
5.77
6.39
mmol/l
—
6
133
29
186
1.56
1.48
4.0
3.3
—
—
—
0
0
51
368
1.39
1.47
1.4
1.5
25.56
31.34
ng/l
0.71
51
368
687
7418
0.91
1.46
3.6
3.5
1.23
1.03
e6/l
0.53
417
4308
36
245
1.47
1.42
1.2
1.2
182.00
174.60
miu/ml
—
5
38
191
1631
1.18
1.41
1.3
1.3
44.78
69.43
au/ml
0.86
11
121
57
424
1.35
1.38
1.3
1.3
72.54
76.72
mu/l
0.06
48
367
30
198
1.52
1.37
1.3
1.4
1.26
1.08
nmol/l
0.43
21
141
35
239
1.47
1.36
1.8
1.8
6.96
7.21
mmol/l
0.26
30
164
291
2574
1.14
1.36
1.6
1.7
1.50
1.53
g/l
0.28
245
2200
5
17
2.94
1.36
1.0
1.1
—
—
—
0
0
54
400
1.35
1.35
1.5
1.3
271.55
277.27
mosm/kgh2o
1.02
44
288
0
40
0.00
1.32
0.0
1.3
—
64.60
—
0
40
27
176
1.54
1.31
1.0
1.1
—
—
—
0
0
1429
13669
1.07
1.29
4.2
3.9
127.18
117.11
e6/l
0.06
1178
10861
58
439
1.33
1.27
1.0
1.1
—
—
—
0
0
1517
14553
1.07
1.25
4.7
4.4
114.49
110.54
e6/l
0.05
1194
11052
53
397
1.34
1.25
1.3
1.3
182170.13
200282.58
e6/l
0.05
31
273
35
245
1.43
1.23
1.4
1.3
—
—
—
0
0
237
2089
1.14
1.20
2.2
2.3
7.58
7.35
g/l
1.18
212
1881
237
2089
1.14
1.20
2.2
2.3
4.18
4.11
g/l
0.72
213
1887
19
117
1.63
1.18
1.9
2.2
—
—
—
0
0
283
2528
1.13
1.17
3.4
3.0
—
—
—
0
0
24
157
1.53
1.17
1.3
1.1
—
—
—
0
0
236
2084
1.14
1.17
2.2
2.3
3.78
3.79
g/l
0.00
212
1879
14
79
1.77
1.16
1.0
1.1
0.47
0.24
u/ml
—
6
41
0
34
0.00
1.16
0.0
7.8
—
7.27
—
0
25
15
87
1.73
1.15
1.1
1.2
20.44
32.64
%
—
9
55
21
134
1.57
1.14
1.1
1.0
—
—
—
0
0
57
440
1.30
1.12
1.1
1.0
—
—
—
0
0
843
7961
1.07
1.09
2.8
3.2
2.46
2.45
mmol/l
1.23
768
7089
545
5066
1.09
1.06
1.4
1.5
—
—
—
0
0
34
245
1.39
1.05
1.9
2.1
498.73
493.28
min
0.11
22
168
14
82
1.71
1.05
1.4
1.7
0.21
0.11
estimate
0.19
14
82
868
9149
0.93
1.02
4.7
4.3
77.14
78.93
%
1.28
844
8972
43
325
1.33
1.00
1.5
1.3
0.23
0.20
nmol/l
1.07
37
276
13
213
0.61
0.99
1.2
1.5
16.68
16.03
umol/l
0.07
13
193
80
658
1.22
0.96
3.0
2.4
1.69
1.18
g/24h
0.74
45
379
13
77
1.69
0.95
1.8
1.5
—
—
—
0
0
436
4037
1.09
0.95
3.4
3.1
4.46
4.37
kpa
0.24
427
3915
202
1800
1.13
0.92
2.5
2.5
21.05
20.82
au/ml
0.01
11
110
327
2994
1.10
0.91
3.5
3.3
129.59
126.99
g/l
1.36
318
2903
102
1195
0.85
0.88
1.5
1.8
20.23
21.51
s
2.44
90
1104
1957
19068
1.05
0.87
5.5
5.4
21.15
22.41
%
3.69
1102
10768
55
441
1.25
0.86
1.6
1.7
4.50
4.20
mmol/24h
0.30
44
383
8
44
1.82
0.85
1.1
1.3
—
—
—
0
0
24
333
0.72
0.85
1.1
1.0
253.74
325.34
ng/l
1.01
19
214
6
31
1.94
0.84
1.0
1.0
—
—
—
0
0
29
213
1.36
0.84
1.2
1.3
—
—
—
0
0
24
332
0.72
0.84
1.1
1.0
592.79
659.79
ng/l
0.36
19
209
0
25
0.00
0.79
0.0
1.5
—
347.56
—
0
25
0
27
0.00
0.77
0.0
1.0
—
—
—
0
0
0
27
0.00
0.77
0.0
12.9
—
275.52
—
0
21
27
200
1.35
0.76
2.9
1.6
101.63
107.43
umol/l
0.28
27
200
10
59
1.70
0.75
1.1
1.1
—
—
—
0
0
26
192
1.36
0.75
1.4
1.2
—
—
—
0
0
56
459
1.22
0.74
1.1
1.2
—
—
—
0
0
200
1812
1.11
0.73
2.2
2.3
10.76
10.32
g/l
0.64
173
1585
20
142
1.41
0.72
1.3
1.2
44.42
41.34
g/l
0.31
11
64
19
264
0.72
0.71
1.8
1.5
—
—
—
0
0
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
5
26
1.92
0.70
2.0
1.7
—
—
—
0
0
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
15
101
1.49
0.70
1.3
2.5
6.67
7.99
mmol/l
—
10
63
28
365
0.77
0.69
2.6
3.5
23.75
44.51
mg/l
0.57
21
292
824
8590
0.95
0.69
3.4
3.3
0.17
0.08
0.31
18
339
5
27
1.85
0.68
1.2
1.3
—
—
—
0
0
12
77
1.56
0.68
1.3
1.7
—
—
—
0
0
33
418
0.79
0.66
1.4
1.4
—
—
—
0
0
14
94
1.49
0.66
1.3
1.2
—
—
—
0
0
21
154
1.37
0.65
1.3
1.9
300.23
375.70
mu/l
0.52
13
113
20
270
0.74
0.64
1.3
1.4
—
—
—
0
0
47
386
1.22
0.64
2.1
2.2
670.52
659.91
ml
0.06
29
232
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
109
967
1.13
0.60
1.1
1.1
83.00
213.30
titre
—
5
20
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
142
1281
1.11
0.59
4.0
3.3
4.29
4.28
pmol/l
0.04
122
1112
10
64
1.56
0.58
1.1
1.2
—
—
—
0
0
191
1754
1.09
0.57
1.9
1.9
—
—
—
0
0
12
81
1.48
0.57
1.3
1.4
—
—
—
0
0
97
859
1.13
0.56
1.2
1.3
24.96
38.72
u/l
1.98
79
746
60
699
0.86
0.55
1.3
1.2
3.73
3.93
mmol/l
0.80
53
646
20
150
1.33
0.55
1.1
1.1
—
—
—
0
0
49
412
1.19
0.55
1.1
1.1
—
—
—
0
0
9
60
1.50
0.54
5.6
4.6
—
—
—
0
0
65
562
1.16
0.53
1.2
1.2
—
—
—
0
0
6
39
1.54
0.53
1.0
1.3
—
—
—
0
0
70
801
0.87
0.52
1.3
1.3
520.47
642.57
mg/l
1.27
62
747
60
517
1.16
0.52
1.6
1.7
4.95
17.26
iu/l
0.43
25
170
22
170
1.30
0.51
1.0
1.1
135.09
133.67
nmol/l
0.08
22
170
28
226
1.24
0.48
2.9
2.6
—
—
—
0
0
57
654
0.87
0.46
1.1
1.1
—
—
—
0
0
8
117
0.68
0.45
1.5
1.5
8.32
7.59
mmol/l
—
8
117
32
264
1.21
0.45
1.2
1.2
—
—
—
0
0
205
2195
0.93
0.45
3.9
3.8
1.02
1.02
ratio
0.29
194
1990
43
366
1.18
0.45
2.1
1.9
218.63
285.76
mu/l
2.67
35
345
24
192
1.25
0.44
1.2
1.2
—
—
—
0
0
833
8584
0.96
0.44
1.3
1.3
—
—
—
0
0
16
121
1.32
0.44
1.8
2.2
51341.80
23594.30
e6/l
—
10
67
53
607
0.87
0.43
2.3
1.7
—
—
—
0
0
101
917
1.10
0.42
1.6
1.6
81.75
33.24
u/ml
0.79
13
149
24
194
1.24
0.42
3.0
2.6
37.86
32.89
%
0.75
14
112
0
16
0.00
0.41
0.0
1.1
—
1.82
—
0
11
49
426
1.15
0.41
1.2
1.2
351.28
288.31
u/ml
0.83
25
244
8
60
1.33
0.40
1.1
1.1
—
—
—
0
0
21
260
0.81
0.40
2.2
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
827
8045
1.04
0.39
5.7
4.4
272.94
634.36
ng/l
1.83
745
7281
24
196
1.23
0.39
2.3
2.3
28.54
24.77
iu/ml
—
8
32
95
865
1.10
0.39
1.3
1.5
—
—
—
0
0
56
633
0.88
0.38
1.9
1.9
3.13
3.11
mmol/l
0.04
42
476
5
36
1.39
0.38
2.4
2.8
7.70
6.05
mg/l
—
5
27
12
89
1.35
0.37
1.0
1.1
—
—
—
0
0
9
68
1.32
0.37
1.0
1.1
—
—
—
0
0
9
68
1.32
0.37
1.1
1.1
—
—
—
0
0
26
216
1.21
0.36
1.0
1.1
—
—
—
0
0
13
99
1.31
0.35
1.2
1.1
—
—
—
0
0
821
8421
0.97
0.35
4.8
3.8
1.00
0.21
—
5
115
75
680
1.10
0.34
1.8
1.8
184.54
192.91
pmol/l
0.38
67
617
37
320
1.16
0.34
1.1
1.2
5.04
6.35
u/ml
0.19
24
141
13
100
1.30
0.33
1.9
1.7
—
—
—
0
0
18
220
0.82
0.32
1.1
1.1
—
127.14
—
0
7
19
155
1.23
0.32
1.0
1.0
—
—
—
0
0
15
187
0.80
0.32
1.0
2.1
81.50
65.05
mg/l
—
6
138
90
829
1.09
0.31
1.1
1.1
—
—
—
0
0
60
542
1.11
0.30
1.2
1.3
—
—
—
0
0
7
99
0.71
0.30
1.0
1.8
—
—
—
0
0
7
99
0.71
0.30
1.0
1.1
1794.00
1567.34
miu/ml
—
7
99
107
1149
0.93
0.30
3.1
2.9
59.27
59.39
%
0.02
102
1105
7
56
1.25
0.29
1.0
1.3
6.71
15.16
mm/h
—
7
56
94
871
1.08
0.29
1.6
1.8
47.83
48.87
nmol/l
0.19
89
817
8
106
0.75
0.29
1.1
1.1
—
—
—
0
0
51
459
1.11
0.28
1.2
1.4
132.55
160.85
au/ml
0.72
11
139
14
112
1.25
0.28
2.4
1.6
43.70
56.36
ug/l
0.69
14
106
13
103
1.26
0.28
47.5
25.9
153.31
108.85
ug/l
1.42
13
88
8
63
1.27
0.27
1.0
1.0
—
—
—
0
0
12
95
1.26
0.26
1.3
1.4
31.24
24.89
g/l
1.58
12
76
75
693
1.08
0.26
1.1
1.2
—
—
—
0
0
9
72
1.25
0.25
1.1
1.5
325.67
309.86
nmol/24h
—
9
72
110
1034
1.07
0.25
1.5
1.5
0.31
0.31
mg/l
0.05
49
446
57
522
1.09
0.24
1.3
1.3
—
—
—
0
0
400
3884
1.03
0.24
2.2
2.2
12.09
11.99
nmol/l
0.08
323
3329
59
543
1.09
0.23
2.1
2.1
—
—
—
0
0
12
97
1.24
0.23
1.1
1.4
—
—
—
0
0
97
1030
0.94
0.22
22.9
13.5
—
—
—
0
0
34
378
0.90
0.21
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
2.14
—
0
10
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
33
297
1.11
0.20
1.4
2.0
9.18
8.08
mmol/l
0.66
33
297
52
480
1.08
0.20
1.2
1.1
—
—
—
0
0
6
49
1.22
0.20
2.8
1.8
50.52
35.54
pmol/l
—
6
36
37
406
0.91
0.19
4.6
3.4
10.39
11.80
index
0.34
18
210
36
328
1.10
0.18
1.4
1.2
281.47
317.03
nmol/l
0.71
30
235
18
206
0.87
0.18
1.1
1.1
—
3.40
—
0
10
12
100
1.20
0.18
1.1
1.4
—
—
—
0
0
19
215
0.88
0.16
1.5
1.3
—
—
—
0
0
12
101
1.19
0.16
1.1
1.4
—
—
—
0
0
8
69
1.16
0.16
1.8
1.4
0.89
0.91
ug/l
—
8
63
169
1749
0.96
0.16
1.2
1.2
—
—
—
0
0
10
83
1.21
0.15
1.1
1.4
—
—
—
0
0
23
207
1.11
0.15
1.4
1.5
—
—
—
0
0
7
86
0.81
0.14
1.0
1.3
—
—
—
0
0
13
112
1.16
0.14
1.1
1.4
152.15
181.20
mmol/24h
0.83
13
112
18
160
1.13
0.14
1.6
2.4
2162.31
1918.74
ml
0.50
13
125
124
1196
1.04
0.13
1.1
1.1
—
1.63
—
0
12
8
100
0.80
0.13
5.5
8.7
5.81
5.61
kpa
—
8
100
13
149
0.87
0.13
4.5
3.5
61.50
52.95
%
0.96
13
143
420
4128
1.02
0.13
2.9
2.7
10.49
10.70
umol/l
0.06
374
3701
37
345
1.07
0.12
2.4
2.2
1.46
2.13
ug/l
1.78
30
279
84
805
1.04
0.12
1.3
1.3
—
—
—
0
0
16
142
1.13
0.12
1.9
2.2
33579.90
6210.80
e6/l
—
10
97
24
220
1.09
0.11
1.3
1.2
75.50
94.10
pmol/l
1.23
24
220
42
396
1.06
0.11
2.2
1.7
11.15
10.12
%
0.64
42
396
71
681
1.04
0.11
2.9
1.3
0.91
0.84
nmol/l
0.43
53
556
1021
10126
1.01
0.10
6.2
6.3
—
—
—
0
0
29
311
0.93
0.10
1.6
1.7
—
2.00
—
0
5
34
362
0.94
0.10
1.7
2.0
2.38
1.13
u/field
0.45
13
202
11
96
1.15
0.10
1.1
1.4
—
—
—
0
0
11
96
1.15
0.10
1.1
1.4
—
—
—
0
0
120
1235
0.97
0.10
3.9
4.4
—
—
—
0
0
24
222
1.08
0.10
1.8
2.2
—
—
—
0
0
5
45
1.11
0.09
1.0
1.2
—
8.17
—
0
16
266
2706
0.98
0.09
2.7
2.9
5.92
6.01
ph
0.74
173
2003
14
126
1.11
0.09
1.9
1.9
—
—
—
0
0
6
56
1.07
0.08
1.2
1.5
—
—
—
0
0
66
684
0.96
0.08
1.3
1.4
365.24
955.07
e6/l
1.13
54
549
20
186
1.08
0.07
1.4
1.4
141.74
149.04
pmol/l
0.12
20
186
8
78
1.03
0.07
2.8
1.3
—
—
—
0
0
1364
13693
0.99
0.06
3.8
3.7
0.79
0.86
ug/l
1.57
1004
10213
66
678
0.97
0.05
1.3
1.3
25.29
37.03
e6/l
0.26
48
514
15
161
0.93
0.05
1.3
1.4
1.42
1.44
g/l
0.13
15
161
10
110
0.91
0.05
1.0
1.2
—
0.15
—
0
7
44
426
1.03
0.05
1.0
1.1
31.83
463.19
iu/ml
—
6
73
111
1093
1.02
0.04
4.0
3.7
1.59
1.79
index
0.17
56
594
46
473
0.97
0.04
2.7
3.6
9.59
8.68
nmol/l
0.09
46
465
19
200
0.95
0.03
1.8
1.8
0.50
2.94
u/field
—
10
134
31
299
1.04
0.03
1.2
1.4
—
—
—
0
0
12
112
1.07
0.03
2.5
2.8
108.67
376.00
ug/l
0.47
12
112
87
858
1.01
0.02
3.7
3.7
24.96
33.83
mg/l
1.63
66
620
27
279
0.97
0.02
2.5
2.8
32.95
35.02
mg/l
0.08
19
218
19
197
0.96
0.01
1.1
1.1
4.86
2.90
eliau/ml
—
5
43
32
313
1.02
0.01
1.1
1.3
—
—
—
0
0
20
194
1.03
0.00
1.1
1.1
—
—
—
0
0
52
522
1.00
0.00
1.0
1.2
—
—
—
0
0
32
325
0.98
0.00
1.3
1.2
—
—
—
0
0
392
3925
1.00
0.00
3.2
2.8
0.56
0.49
e6/l
0.13
381
3814
11
111
0.99
0.00
1.2
1.4
0.07
0.13
nmol/l
—
6
82
14
137
1.02
0.00
2.7
2.2
0.62
0.62
mmol/l
0.09
14
137
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.08
—
0
6
5
53
0.94
-0.00
1.2
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
362.50
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
3.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
14.5
12.0
4.05
5.18
mmol/l
—
6
68
0
5
0.00
-0.00
0.0
1.2
—
18.74
—
0
5
7
74
0.95
-0.00
1.0
1.6
2.21
1.79
umol/l
—
7
69
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint J10_PLEURPLAGUE and mortality.

Females

Parameter HR [95% CI] p-value
J10_PLEURPLAGUE 1.23 [1.1, 1.37] < 0.001
Birth year 0.998 [0.99, 1.01] 0.658

During the follow-up period (1.1.1998 — 31.12.2019), 1033 out of 2963 females with J10_PLEURPLAGUE died.

Males

Parameter HR [95% CI] p-value
J10_PLEURPLAGUE 1.37 [1.26, 1.49] < 0.001
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 7086 out of 17328 males with J10_PLEURPLAGUE died.

Mortality risk

Mortality risk for people of age

years, who have J10_PLEURPLAGUE.

N-year risk Females Males
1 0.142% 0.227%
5 0.715% 1.345%
10 1.869% 3.572%
15 3.924% 6.586%
20 7.039% 11.352%

Relationships between endpoints

Index endpoint: J10_PLEURPLAGUE – Pleural plaque

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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