Benign neoplasm: Uterine tubes and ligaments

CD2_BENIGN_UTERINE_TUBES_LIGAMENTS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28.7&
  • Hospital discharge: ICD-9 2210
  • Hospital discharge: ICD-8 2210
  • Cause of death: ICD-10 D28.7&
  • Cause of death: ICD-9 2210
  • Cause of death: ICD-8 2210

2 out of 7 registries used, show all original rules.

236

4. Check minimum number of events

None

236

5. Include endpoints

None

236

6. Filter based on genotype QC (FinnGen only)

219

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D28
Name in latin
Neoplasma benignum alterius organi genitalis feminini specificati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1728 1728 -
Only index persons 1555 1555 -
Unadjusted period prevalence (%)
Whole population 0.05 0.05 -
Only index persons 0.06 0.06 -
Median age at first event (years)
Whole population - 39.39 -
Only index persons - 37.97 -

-FinnGen-

Key figures

All Female Male
Number of individuals 219 219 -
Unadjusted period prevalence (%) 0.08 0.08 -
Median age at first event (years) 36.38 36.38 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
222
Matched controls
2220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
22101
ICD-8 Finland
Benign neoplasm of other female genital organs, Fallopian tube and broad ligament
+∞
127.8
110
*
2210A
ICD-9 Finland
Benign neoplasm of other female genital organs, Fallopian tube and uterine ligaments
+∞
70.7
64
*
D28.7
ICD-10 Finland
Benign neoplasm: Other specified female genital organs
+∞
43.1
40
*
8204
FHL
Salpingo-oophorectomy
10.8
9.7
18
18
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
6.6
6.3
15
24

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
192
2.32
5.00
2.8
3.7
7.30
7.36
ph
0.47
26
128
136
1654
0.54
4.52
21.2
20.6
13.79
13.75
%
0.13
136
1637
129
1510
0.65
2.46
4.2
4.3
—
0.40
—
0
5
16
71
2.35
2.40
3.5
3.4
—
—
—
0
0
57
767
0.65
2.02
3.4
3.8
7.40
7.40
ph
0.17
41
539
96
779
1.41
1.72
3.8
3.6
—
0.83
—
0
6
0
49
0.00
1.70
0.0
2.1
—
7.52
—
0
49
20
113
1.85
1.67
2.5
1.9
—
—
—
0
0
10
44
2.33
1.58
2.0
2.3
7.74
7.92
kpa
—
10
44
79
956
0.73
1.42
2.4
1.9
1.21
1.30
mmol/l
0.61
64
785
8
35
2.33
1.28
1.4
2.0
90.02
90.66
%
—
8
35
105
898
1.32
1.25
2.3
2.1
—
—
—
0
0
98
832
1.32
1.22
4.1
4.0
26.58
31.82
ng/l
0.27
75
624
18
113
1.65
1.09
1.2
1.3
—
—
—
0
0
74
877
0.77
1.07
2.8
3.1
2.35
2.37
mmol/l
0.65
65
794
5
23
2.20
0.98
1.8
2.7
—
—
—
0
0
45
351
1.35
0.98
2.4
2.4
13.07
12.69
umol/l
0.15
40
328
204
1954
1.54
0.97
16.8
16.5
18.36
21.16
mg/l
0.70
164
1605
109
960
1.27
0.97
2.5
2.8
—
—
estimate
—
0
0
79
669
1.28
0.96
2.1
2.4
—
—
—
0
0
61
732
0.77
0.95
3.7
3.4
18.07
46.15
e6/l
1.73
49
560
52
634
0.77
0.91
3.6
3.3
0.19
0.46
e6/l
1.82
41
457
40
314
1.33
0.84
2.3
2.4
21.54
21.46
%
0.01
35
290
26
191
1.41
0.81
2.8
2.4
5.97
6.12
ph
0.33
17
131
215
2098
1.79
0.80
26.1
25.4
256.63
258.42
e9/l
0.17
210
2055
215
2099
1.77
0.80
26.0
25.4
4.41
4.37
e12/l
0.68
209
2047
215
2099
1.77
0.80
26.1
25.4
6.49
6.59
e9/l
0.36
209
2046
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
102.50
—
0
24
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
105
937
1.23
0.78
3.7
4.1
6.19
6.33
ph
0.53
57
514
44
538
0.77
0.78
2.6
2.6
2.44
2.46
mmol/l
0.63
38
481
35
439
0.76
0.75
3.5
4.4
2555.15
116.69
ng/l
0.49
26
353
119
1079
1.22
0.75
2.6
2.5
84.01
82.17
nmol/l
0.26
110
970
5
25
2.02
0.73
1.4
1.5
1214.00
151.28
u/ml
—
5
25
59
689
0.80
0.71
7.5
6.3
—
—
—
0
0
127
1165
1.21
0.69
3.9
4.5
0.00
0.00
estimate
-0.00
18
242
210
2041
1.53
0.69
18.6
19.8
139.94
139.80
mmol/l
0.30
203
1997
212
2065
1.59
0.68
13.4
12.8
24.46
23.24
u/l
0.59
204
1998
81
713
1.21
0.68
2.6
2.3
82.62
62.18
u/l
0.59
74
655
210
2044
1.51
0.65
18.8
19.9
3.94
3.95
mmol/l
0.24
203
1994
17
121
1.44
0.64
3.1
2.5
—
—
—
0
0
28
353
0.76
0.63
3.7
3.1
6.93
4.90
e6/l
0.23
15
161
74
835
0.83
0.63
4.4
4.2
360.82
101.24
e6/l
0.37
50
579
10
63
1.62
0.63
1.6
2.2
25.77
25.47
mmol/l
—
10
63
17
122
1.43
0.62
1.2
1.4
—
55.19
—
0
8
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
40
330
1.26
0.60
2.3
2.3
2.36
2.37
g/l
0.06
35
303
127
1175
1.19
0.60
4.1
4.6
0.00
13.84
estimate
0.80
19
253
198
1918
1.30
0.54
7.4
6.7
39.22
39.54
mmol/mol
0.27
188
1790
127
1185
1.17
0.51
4.1
4.5
0.00
0.00
estimate
-0.00
19
235
212
2076
1.47
0.51
22.2
22.2
71.52
71.19
umol/l
0.09
207
2046
108
996
1.16
0.50
7.6
5.9
30.35
28.13
%
1.52
102
930
19
241
0.77
0.46
1.5
1.4
—
—
—
0
0
19
241
0.77
0.46
1.5
1.6
—
—
—
0
0
7
49
1.44
0.46
1.1
2.0
—
—
—
0
0
47
535
0.85
0.43
1.5
1.3
4.63
2.35
u/ml
—
10
145
5
32
1.58
0.42
1.4
1.1
—
—
—
0
0
5
32
1.58
0.42
1.4
1.1
—
—
—
0
0
10
70
1.45
0.42
1.3
1.3
—
—
—
0
0
106
987
1.14
0.41
7.7
6.0
8.56
8.70
%
0.26
98
913
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
3.1
—
582.55
—
0
11
0
16
0.00
0.41
0.0
2.6
—
463.27
—
0
11
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
27
224
1.23
0.41
2.0
1.6
—
—
—
0
0
112
1192
0.88
0.40
5.1
5.9
9.51
10.05
umol/l
0.42
104
1123
33
280
1.21
0.40
1.2
1.3
—
—
—
0
0
14
106
1.34
0.40
4.3
4.1
37.02
36.94
°c
1.40
14
106
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
65
716
0.87
0.39
3.8
3.5
—
—
—
0
0
9
68
1.34
0.38
1.4
2.3
7.41
7.42
ph
—
9
68
72
658
1.14
0.37
4.2
4.7
0.06
0.00
estimate
0.48
18
232
197
1923
1.22
0.36
7.3
6.3
1.84
1.92
mu/l
0.50
179
1775
9
71
1.28
0.36
1.3
1.6
82.78
184.46
ug/l
—
9
65
12
90
1.35
0.36
1.6
1.3
—
—
—
0
0
79
727
1.13
0.36
3.0
2.1
130.28
150.03
u/l
0.27
74
686
205
2010
1.26
0.35
6.8
6.4
2.77
2.74
mmol/l
0.21
191
1848
61
553
1.14
0.35
2.9
2.3
2.96
3.14
mg/l
0.29
52
477
23
274
0.82
0.35
1.6
1.3
—
—
—
0
0
37
323
1.17
0.34
1.5
1.4
146.67
653.18
titre
—
6
85
16
198
0.79
0.34
1.5
1.4
—
—
—
0
0
105
989
1.12
0.32
7.8
5.9
0.80
0.74
%
0.63
96
909
12
92
1.32
0.32
1.1
1.2
—
1.51
—
0
7
45
501
0.87
0.31
1.6
1.7
1.01
1.21
mg/l
0.38
31
406
49
541
0.88
0.30
1.3
1.4
—
—
—
0
0
18
216
0.82
0.29
1.4
1.4
—
—
—
0
0
41
456
0.88
0.28
2.1
1.5
2.69
2.42
g/l
0.34
26
262
19
159
1.21
0.28
1.3
2.7
—
—
—
0
0
22
256
0.84
0.27
5.7
6.7
7.44
7.42
ph
0.76
16
151
20
234
0.84
0.26
2.1
2.4
4.20
6.08
umol/l
2.24
20
205
190
1861
1.15
0.25
5.2
4.5
1.27
1.25
mmol/l
0.17
173
1689
115
1099
1.10
0.25
7.6
5.6
1.92
1.98
e9/l
0.20
101
962
104
990
1.10
0.25
7.8
5.8
3.04
2.77
%
0.65
97
914
113
1082
1.09
0.23
7.5
5.7
0.05
0.04
e9/l
0.58
99
920
5
38
1.32
0.23
1.6
1.6
22.40
30.33
umol/l
—
5
33
112
1073
1.09
0.23
7.6
5.7
0.55
0.56
e9/l
0.07
97
913
92
874
1.09
0.22
3.8
4.5
0.00
0.01
estimate
0.50
15
196
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
201
1980
1.16
0.21
6.1
5.4
4.76
4.80
mmol/l
0.25
189
1826
116
1115
1.08
0.21
7.6
5.9
0.21
0.18
e9/l
1.10
101
963
0
11
0.00
0.21
0.0
1.1
—
0.05
—
0
6
0
11
0.00
0.21
0.0
1.4
—
146.36
—
0
11
0
10
0.00
0.21
0.0
4.3
—
43.75
—
0
10
0
10
0.00
0.21
0.0
2.5
—
1.10
—
0
10
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
142.97
—
0
13
72
759
0.92
0.19
3.5
3.1
6.30
6.38
mmol/l
0.07
64
617
11
132
0.82
0.19
1.5
1.3
—
—
—
0
0
19
166
1.16
0.18
1.3
1.3
—
—
—
0
0
198
2006
0.88
0.18
14.8
14.5
—
—
—
0
0
7
58
1.21
0.18
1.0
1.2
—
—
—
0
0
7
63
1.11
0.17
1.0
1.1
—
—
—
0
0
7
63
1.11
0.17
7.3
9.4
—
—
—
0
0
5
66
0.75
0.17
2.4
1.2
—
142.86
—
0
7
127
1233
1.07
0.16
4.6
4.7
6.65
6.64
mmol/l
0.03
120
1157
6
79
0.75
0.16
1.5
1.2
—
—
—
0
0
72
687
1.07
0.15
1.8
1.7
21.97
21.98
nmol/l
0.00
56
583
122
1185
1.07
0.15
4.7
6.1
1.22
1.22
mmol/l
0.59
105
1022
26
285
0.90
0.15
1.6
1.4
—
—
—
0
0
15
171
0.87
0.15
1.2
1.2
—
—
—
0
0
15
171
0.87
0.15
2.9
4.3
—
—
—
0
0
39
416
0.92
0.13
1.9
3.0
482.94
482.03
mosm/kgh2o
0.01
32
370
199
1968
1.11
0.13
6.3
5.5
5.79
5.93
mmol/l
1.14
183
1799
110
1069
1.06
0.13
4.9
5.5
1.22
1.22
mmol/l
0.34
95
983
43
405
1.08
0.13
1.6
1.7
1264.77
1269.13
nmol/l
0.01
31
301
13
148
0.87
0.13
1.1
1.4
—
—
—
0
0
17
189
0.89
0.12
5.1
4.6
0.14
0.24
%
—
7
46
100
971
1.05
0.12
3.6
3.0
104.74
95.42
ug/l
0.33
90
893
79
818
0.95
0.12
3.9
3.3
—
—
—
0
0
20
182
1.11
0.11
1.3
1.5
—
—
—
0
0
49
467
1.06
0.11
1.9
1.7
376.51
19730212.83
pmol/l
0.50
41
370
13
115
1.14
0.11
1.2
1.1
—
—
—
0
0
46
482
0.94
0.10
4.5
4.5
—
—
—
0
0
45
429
1.06
0.10
1.3
1.3
15.98
12.64
u/ml
0.09
23
162
173
1710
1.05
0.08
6.1
5.0
14.92
14.99
pmol/l
0.14
156
1566
129
1268
1.04
0.08
3.2
3.1
65.89
47.25
u/l
0.62
119
1182
7
64
1.10
0.08
2.6
2.6
—
—
—
0
0
24
256
0.93
0.08
5.3
6.6
1.69
1.35
mmol/l
0.09
19
220
27
254
1.07
0.08
3.8
4.1
6.46
8.92
ug/l
0.30
22
210
8
78
1.03
0.07
1.3
1.8
—
—
—
0
0
54
522
1.05
0.07
5.0
4.8
1.02
1.02
kg/l
1.10
38
346
7
82
0.85
0.07
1.6
1.6
—
—
—
0
0
102
1001
1.04
0.06
12.1
12.3
1.21
1.19
inr
0.11
90
819
58
563
1.04
0.06
4.9
4.3
—
0.13
—
0
8
74
757
0.97
0.06
4.0
3.9
6.13
6.00
mg/mmol
0.01
43
414
14
129
1.09
0.06
5.0
6.2
27.31
25.05
mmol/l
0.73
14
129
93
947
0.97
0.05
10.5
11.5
0.00
0.00
e9/l
1.06
79
777
17
181
0.93
0.05
4.4
4.2
0.25
0.85
%
—
8
52
60
614
0.97
0.04
2.6
3.9
0.00
0.00
estimate
-0.00
14
196
34
328
1.04
0.04
1.5
1.2
—
—
—
0
0
12
129
0.93
0.03
1.2
1.3
—
—
—
0
0
19
181
1.05
0.03
4.7
4.3
0.11
0.16
%
—
9
50
101
1021
0.98
0.03
2.4
2.2
104.08
100.39
pmol/l
0.29
50
467
46
470
0.97
0.03
1.4
1.4
37.26
35.31
iu/ml
0.05
14
165
73
740
0.98
0.02
3.4
3.3
22.20
26.89
mg/l
0.18
46
429
162
1629
0.98
0.02
8.1
7.8
81.66
79.95
u/l
0.13
151
1527
121
1217
0.99
0.01
9.6
9.1
4.04
3.97
e9/l
0.12
104
1064
24
234
1.03
0.00
2.4
3.0
7.40
7.39
ph
0.29
11
131
53
536
0.99
0.00
2.1
2.6
338.98
327.76
umol/l
0.42
43
465
19
193
0.98
0.00
4.7
4.2
0.78
0.91
%
—
9
62
29
295
0.98
0.00
1.8
2.0
—
—
—
0
0
27
275
0.98
0.00
2.3
2.0
122.33
120.97
ug/g
0.01
21
214
56
565
0.99
0.00
3.9
3.8
—
—
—
0
0
11
105
1.05
0.00
1.2
1.3
—
—
—
0
0
19
188
1.01
0.00
1.3
3.3
16.68
39.32
u/ml
1.80
19
182
197
1968
1.01
0.00
6.3
5.3
1.57
1.62
mmol/l
0.90
183
1807
19
188
1.01
0.00
4.4
6.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.4
—
0.68
—
0
5
5
58
0.86
-0.00
2.0
5.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
0.62
—
0
7
0
7
0.00
-0.00
0.0
35.6
—
89.29
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
71.98
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
114.33
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
4.86
—
0
5
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
3.38
4.01
mmol/l
—
5
45
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1425.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
226.12
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_UTERINE_TUBES_LIGAMENTS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_UTERINE_TUBES_LIGAMENTS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_UTERINE_TUBES_LIGAMENTS – Benign neoplasm: Uterine tubes and ligaments

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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