auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1297 |
4. Check minimum number of eventsNone |
1297 |
5. Include endpointsNone |
1297 |
6. Filter based on genotype QC (FinnGen only) |
1195 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H65-H75
- Name in latin
- Aliae morbositates tubae auditivae
Similar endpoints
↥List of similar endpoints to
Other disorders of Eustachian tube
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6062 | 3566 | 2467 |
| Only index persons | 5812 | 3458 | 2354 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.07 |
| Only index persons | 0.11 | 0.13 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 48.24 | 47.07 | 49.93 |
| Only index persons | 48.07 | 46.99 | 49.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1195 | 775 | 420 |
| Unadjusted period prevalence (%) | 0.25 | 0.28 | 0.19 |
| Median age at first event (years) | 56.32 | 52.30 | 63.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1244
- Matched controls
- 12440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
404.3
307.7
408
15
H69.0
ICD-10 Finland
Patulous Eustachian tube
779.0
307.7
623
16
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
221.0
307.7
248
14
UDC00
NOMESCO Finland
Ear microscopy
9.4
219.4
300
405
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.3
194.9
427
947
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
52.9
193.0
111
23
DFF00
NOMESCO Finland
Pure tone audiometry
6.9
185.7
350
668
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
225.9
172.9
175
9
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
21.9
131.3
99
49
H66.0
ICD-10 Finland
Acute suppurative otitis media
6.9
119.3
203
341
H66.9
ICD-10 Finland
Otitis media, unspecified
6.5
96.4
172
301
DC1AD
NOMESCO Finland
Temporalbone CT
35.2
85.2
54
16
H92.0
ICD-10 Finland
Otalgia
5.3
85.0
188
401
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.2
84.4
195
432
H65.3
ICD-10 Finland
Chronic mucoid otitis media
105.1
81.1
88
9
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
146.2
78.0
82
6
H65.2
ICD-10 Finland
Chronic serous otitis media
138.6
73.8
78
6
H29
ICPC
Ear symptom/complaint other
3.5
63.7
264
891
H65.0
ICD-10 Finland
Acute serous otitis media
16.6
63.5
54
34
R01AD09
ATC
mometasone; nasal
2.7
63.5
747
4429
R01AD12
ATC
fluticasone furoate; nasal
2.5
54.6
540
2884
R01AD08
ATC
fluticasone; nasal
2.5
51.6
477
2455
R01AD58
ATC
fluticasone, combinations; nasal
2.5
46.3
434
2227
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
44.0
42
*
H01
ICPC
Ear pain/earache
3.0
43.6
229
877
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
38.7
37
*
H93.1
ICD-10 Finland
Tinnitus
3.3
35.0
143
470
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.6
34.9
121
358
H13
ICPC
Plugged feeling ear
2.4
34.2
300
1466
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.5
33.3
258
1191
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
9.0
32.0
40
46
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
31.4
30
*
DFF15
NOMESCO Finland
Speech audiometry
3.8
30.4
96
266
4122
FHL
Tympanostomy (tympanic tube)
84.8
29.9
33
*
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
29.3
28
*
TDA90
NOMESCO Finland
Removal wax from ear
8.3
28.7
38
47
H02
ICPC
Hearing complaint
2.4
28.3
226
1051
UDM02
NOMESCO Finland
Sinoscopy
5.4
26.4
53
102
DCD00
NOMESCO Finland
Myringoplasty
265.9
25.8
26
*
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
8.3
25.7
34
42
J31.0
ICD-10 Finland
Chronic rhinitis
2.7
25.6
152
613
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
24.0
24.9
35
15
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
24.2
506
3340
SPAT1043
SPAT
Audiometry
2.6
23.7
152
636
J01FA10
ATC
azithromycin; systemic
1.8
22.9
765
5795
A02BC05
ATC
esomeprazole; systemic
1.8
22.5
531
3617
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.7
22.0
130
522
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.6
21.4
72
208
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.7
21.3
124
494
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
21.2
396
2500
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
6.3
21.2
36
59
H91.9
ICD-10 Finland
Hearing loss, unspecified
3.1
21.0
92
314
H02AB06
ATC
prednisolone; systemic
1.8
20.8
608
4380
N07CA01
ATC
betahistine; oral
2.8
20.4
111
427
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.0
19.3
56
146
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
18.6
309
1869
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
18.5
678
5136
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.8
18.4
355
2246
A02BC02
ATC
pantoprazole; systemic
1.8
18.1
860
6972
M79.6
ICD-10 Finland
Pain in limb
1.7
18.0
585
4282
R42
ICD-10 Finland
Dizziness and giddiness
1.9
17.9
302
1831
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
17.9
61
178
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
17.7
17
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
17.6
338
2131
N03AX16
ATC
[U] pregabalin
1.8
17.5
299
1819
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.2
17.4
47
116
J01AA02
ATC
doxycycline; systemic
1.8
17.1
960
8091
M03BX02
ATC
tizanidine; oral
1.7
17.0
793
6341
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
16.9
350
2254
G44.2
ICD-10 Finland
Tension-type headache
2.0
16.6
208
1141
R06AX27
ATC
desloratadine; oral
1.7
16.4
393
2633
EMB30
NOMESCO Finland
Adenotomy
5.7
16.1
30
54
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
13.8
16.0
27
20
J01CA04
ATC
amoxicillin; systemic
1.9
15.9
1037
9010
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.2
15.9
63
202
R13
ICD-10 Finland
Dysphagia
2.5
15.9
109
469
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
6.5
15.9
26
41
J02AC01
ATC
fluconazole; systemic
1.6
15.8
511
3698
R51.80
ICD-10 Finland
Headache
1.9
15.4
229
1328
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
38.6
15.4
19
5
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
15.4
111
489
H69
ICD-10 Finland
Other disorders of Eustachian tube
29.0
15.2
20
7
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
15.2
144
711
H60.8
ICD-10 Finland
Other otitis externa
3.3
15.2
57
177
J01DB01
ATC
cefalexin; oral
1.9
15.0
1034
9023
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
15.0
358
2385
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
3.9
14.8
43
112
H60.3
ICD-10 Finland
Other infective otitis externa
3.9
14.7
43
113
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
14.6
14
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
14.6
14
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
14.6
540
4016
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
12.1
14.1
25
21
SPAT1044
SPAT
Tympanometry
4.0
13.9
39
99
UKC02
NOMESCO Finland
Cystoscopy
1.9
13.9
190
1071
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
13.7
517
3846
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
14.9
13.6
22
15
L01
ICPC
Neck symptom/complaint
1.8
13.5
226
1356
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
13.5
312
2054
EMB10
NOMESCO Finland
Tonsillectomy
2.5
13.4
86
359
J01MA02
ATC
ciprofloxacin; systemic
1.6
13.2
448
3241
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.3
13.1
50
157
R03AC02
ATC
salbutamol; inhalant
1.6
13.0
694
5564
Z71.8
ICD-10 Finland
Other specified counselling
1.6
12.9
445
3230
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
12.8
650
5147
ZZG00
NOMESCO Finland
Graft of cartilage
32.4
12.6
16
5
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
12.6
325
2197
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
12.5
12
*
DGW99
NOMESCO Finland
Other operation on eustachian tube
+∞
12.5
12
*
DGB00
NOMESCO Finland
Obliteration of eustachian tube
+∞
12.5
12
*
A02BC03
ATC
lansoprazole; oral
1.6
12.5
345
2369
N06AX11
ATC
mirtazapine; oral
1.6
12.5
424
3062
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
131.3
12.5
13
*
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
37.9
12.2
15
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.0
12.2
142
756
DAX08
NOMESCO Finland
Fitting of hearing aid
2.5
12.1
76
314
Z01.2
ICD-10 Finland
Dental examination
1.5
12.1
590
4610
N03AX12
ATC
[U] gabapentin; oral
1.8
12.1
205
1233
R01AD11
ATC
triamcinolone; nasal
2.1
12.0
118
590
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
12.0
105
502
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
12.0
138
732
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.6
11.9
71
286
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.4
11.8
85
374
H04
ICPC
Ear discharge
3.0
11.6
52
180
DHB50
NOMESCO Finland
Turbinoplasty
3.3
11.6
44
138
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
11.5
531
4083
N17
ICPC
Vertigo/dizziness
1.8
11.2
168
971
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
11.1
218
1364
R05
ICD-10 Finland
Cough
1.6
11.1
273
1814
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.1
550
4284
4451
FHL
Guitar cutting
4.0
11.1
31
79
J34.2
ICD-10 Finland
Deviated nasal septum
2.4
11.1
74
315
H91.8
ICD-10 Finland
Other specified hearing loss
4.7
11.0
25
54
H71
ICPC
Acute otitis media/myringitis
4.7
11.0
25
54
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
10.9
230
1468
J35.0
ICD-10 Finland
Chronic tonsillitis
2.4
10.9
76
330
R09
ICPC
Sinus symptom/complaint
2.0
10.8
124
657
H27
ICPC
Fear of ear disease
4.6
10.7
25
55
A01
ICPC
Pain general/multiple sites
1.9
10.7
136
746
L03
ICPC
Low back symptom/complaint
1.5
10.6
375
2712
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
5.1
10.5
22
44
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
10.4
10
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
10.4
10
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
10.4
10
*
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.1
10.4
43
142
L17
ICPC
Foot/toe symptom/complaint
1.5
10.3
384
2805
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
10.3
195
1208
K08.80
ICD-10 Finland
Toothache NOS
1.9
10.3
129
704
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
10.3
510
3957
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
10.2
108
555
K30
ICD-10 Finland
Functional dyspepsia
1.8
10.2
154
892
R00.2
ICD-10 Finland
Palpitations
2.0
10.2
116
612
D06
ICPC
Abdominal pain localized other
2.0
10.2
117
620
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.3
10.1
75
334
R03DC03
ATC
montelukast; oral
1.7
10.1
212
1349
L08
ICPC
Shoulder symptom/complaint
1.6
10.1
287
1972
R01AD59
ATC
mometasone, combinations; nasal
2.1
10.1
98
488
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
10.1
160
941
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
10.0
264
1780
J01DA01
ATC
[U] cefalexin
1.5
10.0
729
6089
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
40.4
10.0
12
*
R06AE07
ATC
cetirizine; oral
1.5
9.9
533
4193
A04
ICPC
Weakness/tiredness general
1.7
9.7
198
1249
J30.0
ICD-10 Finland
Vasomotor rhinitis
3.0
9.7
42
143
S18
ICPC
Laceration/cut
1.5
9.7
563
4490
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.7
325
2318
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
9.6
668
5507
N02BE01
ATC
paracetamol; systemic, rectal
1.8
9.6
1096
10045
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.8
9.5
47
172
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.8
9.5
148
865
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
9.4
71
319
M25.5
ICD-10 Finland
Pain in joint
1.5
9.4
416
3140
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
9.4
9
*
H73.1
ICD-10 Finland
Chronic myringitis
+∞
9.4
9
*
R02
ICPC
Shortness of breath/dyspnoea
1.7
9.2
164
996
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
9.1
154
922
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
9.1
99
514
ZXA10
NOMESCO Finland
Bilateral
1.7
9.1
199
1279
R49.03
ICD-10 Finland
Atrophic dysphonia
4.6
9.1
21
46
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
9.0
135
780
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.6
9.0
51
201
H61.8
ICD-10 Finland
Other specified disorders of external ear
4.9
8.9
19
39
H61.2
ICD-10 Finland
Impacted cerumen
2.1
8.8
83
408
H60
ICD-10 Finland
Otitis externa
2.2
8.8
76
361
F51.0
ICD-10 Finland
Nonorganic insomnia
1.6
8.8
226
1510
R05
ICPC
Cough
1.5
8.8
309
2218
U02
ICPC
Urinary frequency/urgency
1.7
8.8
190
1217
DCD10
NOMESCO Finland
Tympanoplasty
50.3
8.7
10
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
8.7
159
974
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
8.6
128
737
A02BA02
ATC
ranitidine; systemic
1.6
8.6
213
1412
R5110, ,
SPAT
1.9
8.6
107
583
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.6
305
2195
XKD00
NOMESCO Finland
Uroflowmetry
1.7
8.6
148
892
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.4
8.5
57
243
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
20.2
8.5
12
6
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
8.5
121
689
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.8
8.4
123
705
M01AH05
ATC
etoricoxib; oral
1.4
8.4
748
6389
S21
ICPC
Skin texture symptom/complaint
1.6
8.4
185
1191
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
8.3
8
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
8.3
8
*
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
8.3
8
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
8.3
8
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
8.3
404
3090
M54.8
ICD-10 Finland
Other dorsalgia
2.3
8.3
63
284
H93.9
ICD-10 Finland
Disorder of ear, unspecified
8.6
8.3
17
20
M01AB05
ATC
diclofenac; systemic, rectal
1.4
8.3
776
6677
S29
ICPC
Skin symptom/complaint other
1.6
8.2
245
1695
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.2
326
2397
M01AH03
ATC
valdecoxib; oral
2.1
8.1
74
360
N02AX02
ATC
tramadol; systemic, rectal
1.4
8.1
485
3852
SPAT1263
SPAT
Sampling
1.4
8.0
478
3790
L12
ICPC
Hand/finger symptom/complaint
1.6
8.0
215
1450
J01FA09
ATC
clarithromycin; systemic
1.5
8.0
361
2718
G04CA02
ATC
tamsulosin; oral
1.6
8.0
214
1443
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.9
8.0
98
531
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
8.0
179
1157
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
8.0
477
3786
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
3.7
7.9
24
65
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.7
7.9
137
826
XF402
NOMESCO Finland
ECG with work load test
1.8
7.8
119
690
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.5
7.8
50
209
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.8
870
7682
M77.1
ICD-10 Finland
Lateral epicondylitis
1.9
7.8
100
551
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.7
224
1537
H02AB04
ATC
methylprednisolone; systemic
1.7
7.7
163
1036
U01
ICPC
Dysuria/painful urination
1.9
7.7
103
574
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
7.7
224
1539
M79.1
ICD-10 Finland
Myalgia
1.6
7.7
194
1291
L88
ICPC
Rheumatoid/seropositive arthritis
2.3
7.6
54
237
M31.3
ICD-10 Finland
Wegener granulomatosis
11.9
7.6
13
11
N06AX21
ATC
duloxetine; oral
1.7
7.6
151
946
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
3.0
7.5
32
108
A11
ICPC
Chest pain NOS
1.8
7.5
105
594
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
7.5
295
2161
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
7.4
84
443
R06.5
ICD-10 Finland
Mouth breathing
1.8
7.4
107
611
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
7.4
60
279
J01EA01
ATC
trimethoprim; systemic
1.5
7.4
295
2166
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.0
7.4
20
50
3818X
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Other disorders of Eustachian tube
+∞
7.3
7
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
7.3
7
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.3
315
2348
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
7.3
88
475
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
7.2
187
1250
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
7.2
126
761
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.2
128
777
SPAT1153
SPAT
Removal of sutures
1.4
7.2
347
2638
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
7.2
144
903
K80
ICPC
Cardiac arrhythmia NOS
1.8
7.2
106
610
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.5
7.1
44
181
L13
ICPC
Hip symptom/complaint
1.5
7.1
228
1597
M54.6
ICD-10 Finland
Pain in thoracic spine
1.8
7.1
101
574
K07.60
ICD-10 Finland
Snapping jaw
2.0
7.1
73
372
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
3.8
7.1
21
56
C05AA08
ATC
fluocortolone; rectal, topical
1.7
7.1
150
954
G50.1
ICD-10 Finland
Atypical facial pain
3.1
7.0
28
91
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.0
660
5613
A02BC01
ATC
omeprazole; systemic
1.5
6.9
299
2224
N05CF01
ATC
zopiclone; oral
1.4
6.9
351
2690
H81.3
ICD-10 Finland
Other peripheral vertigo
2.7
6.9
37
142
M01AH01
ATC
celecoxib; oral
1.6
6.9
193
1313
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.2
6.9
27
87
A03
ICPC
Fever
1.5
6.9
208
1440
WX702
NOMESCO Finland
Supraglottic ventilation device
2.0
6.9
73
377
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
6.8
311
2336
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.8
360
2778
M67.4
ICD-10 Finland
Ganglion
1.9
6.8
86
472
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
40.3
6.8
8
*
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
40.3
6.8
8
*
L04AX03
ATC
methotrexate; systemic
1.7
6.8
115
690
H60.4
ICD-10 Finland
Cholesteatoma of external ear
16.8
6.7
10
6
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.5
6.7
22
63
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
6.7
154
999
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
6.7
82
444
SPAT1041
SPAT
Comprehensive hearing test
3.9
6.7
19
49
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.9
6.7
19
49
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
6.7
109
645
J01FA06
ATC
roxithromycin; oral
1.4
6.7
443
3549
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
6.7
112
668
M24.2
ICD-10 Finland
Disorder of ligament
3.4
6.7
23
68
M01AC01
ATC
piroxicam; systemic, rectal
1.7
6.7
137
864
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.5
6.6
40
163
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.1
6.6
27
89
R01AD05
ATC
budesonide; nasal
1.8
6.6
91
513
D01
ICPC
Abdominal pain/cramps general
1.6
6.6
153
996
M54.5
ICD-10 Finland
Low back pain
1.4
6.6
436
3493
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.4
6.6
345
2658
R06AX22
ATC
ebastine; oral
1.5
6.5
201
1395
J01DA06
ATC
[U] cefuroxime
1.6
6.5
158
1039
F45.8
ICD-10 Finland
Other somatoform disorders
1.8
6.5
91
515
ZXA05
NOMESCO Finland
Left side
1.5
6.5
252
1836
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.5
485
3961
H81.0
ICD-10 Finland
Ménière disease
2.8
6.4
30
107
M01AC06
ATC
meloxicam; systemic, rectal
1.4
6.4
401
3177
R12
ICD-10 Finland
Heartburn
1.8
6.4
103
607
4141
FHL
Myringoplasty (also for reasons other than inflammation)
70.2
6.4
7
*
A01AB09
ATC
miconazole; local oral
1.8
6.4
94
540
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
3.8
6.4
19
51
M02AA10
ATC
ketoprofen; topical
1.6
6.4
172
1160
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
6.4
69
359
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
6.3
61
304
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
6.3
54
257
J01CA08
ATC
pivmecillinam; oral
1.4
6.2
476
3892
R74
ICPC
Upper respiratory infection acute
1.4
6.2
402
3201
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
6.2
114
699
S02CA02
ATC
flumetasone and antiinfectives; otic
2.1
6.2
60
300
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.2
541
4517
Z01.7
ICD-10 Finland
Laboratory examination
1.5
6.2
199
1395
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
6.1
125
787
M01AH02
ATC
rofecoxib; oral
1.6
6.1
131
835
ULC02
NOMESCO Finland
Hysteroscopy
2.1
6.1
59
294
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.4
6.1
346
2693
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.8
6.1
95
555
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.1
865
7762
H28
ICPC
Limited function/disability (H)
4.1
6.1
16
39
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.9
6.1
74
401
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
2.7
6.0
30
111
Z01.9
ICD-10 Finland
Special examination, unspecified
1.9
6.0
75
409
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
6.0
146
960
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.4
6.0
40
171
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
6.0
56
276
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
976
8159
1.91
19.27
5.8
4.3
10.16
11.65
mm/h
3.15
933
7648
501
3498
1.72
18.47
2.8
2.6
61.37
84.51
u/l
0.51
470
3262
314
2074
1.69
13.37
1.4
1.3
19.74
9.84
u/ml
1.25
108
808
613
4769
1.56
13.20
5.6
5.1
36.34
35.92
g/l
1.06
579
4498
714
5763
1.56
12.95
7.4
6.6
10.90
11.31
umol/l
0.54
688
5525
648
5119
1.55
12.93
2.8
2.5
78.41
76.86
nmol/l
0.76
599
4655
863
7278
1.61
12.91
5.7
4.5
1792.80
1741.52
e6/l
—
5
109
775
6388
1.57
12.68
10.8
9.5
3.94
4.06
e9/l
0.60
695
5599
678
5434
1.54
12.51
8.9
7.1
1.22
1.21
mmol/l
0.77
604
4715
1162
10700
2.30
12.47
20.4
15.1
20.21
23.11
mg/l
2.65
975
8781
957
8327
1.65
12.10
10.4
8.2
78.19
78.00
u/l
0.03
930
7914
325
2221
1.63
11.93
1.4
1.3
20.65
29.36
iu/ml
1.56
106
666
992
8754
1.66
11.37
5.3
4.5
14.67
14.71
pmol/l
0.16
933
8099
142
777
1.93
11.24
2.4
2.4
17.90
21.29
au/ml
0.26
18
84
607
4860
1.49
10.53
15.9
13.6
1.23
1.21
inr
0.34
513
4031
183
1112
1.76
10.33
2.9
2.2
358.74
381.81
nmol/l
1.03
163
1037
129
708
1.92
10.11
1.3
1.3
58.83
40.93
au/ml
—
6
53
1166
10886
2.13
9.84
22.6
17.4
139.72
139.66
mmol/l
0.39
1152
10686
1167
10901
2.14
9.80
23.0
17.5
3.96
3.96
mmol/l
0.24
1152
10674
762
6456
1.47
9.45
6.1
4.9
6.51
6.62
mmol/l
0.88
729
6093
1107
10191
1.78
9.31
6.6
5.5
1.90
1.88
mu/l
0.08
1052
9520
379
2823
1.49
9.08
1.4
1.3
1.37
1.73
u/ml
0.31
101
786
722
6079
1.45
9.08
4.7
3.8
0.00
0.26
estimate
0.54
125
1204
716
6025
1.44
8.99
4.7
3.8
0.00
5.02
estimate
1.33
130
1279
586
4757
1.44
8.92
2.4
2.1
97.26
96.23
pmol/l
0.21
318
2492
288
2033
1.54
8.87
4.4
3.9
125.54
387.61
ng/l
2.97
214
1519
597
4869
1.43
8.83
8.0
6.5
1.22
1.21
mmol/l
1.06
561
4514
436
3361
1.46
8.70
2.3
2.1
139.95
222.73
u/l
1.77
402
3205
670
5591
1.43
8.67
3.9
3.1
104.40
111.79
ug/l
0.61
641
5255
707
5963
1.43
8.59
4.7
3.8
0.00
0.00
estimate
0.50
131
1261
1199
11386
2.47
8.58
25.1
19.3
76.48
75.06
umol/l
0.71
1193
11278
71
339
2.16
8.17
1.5
1.5
287.14
280.54
ug/g
0.09
44
201
131
775
1.77
8.07
1.7
1.7
—
—
—
0
0
222
1516
1.57
7.85
2.0
2.5
91.41
121.09
ug/g
1.11
176
1216
481
3839
1.41
7.71
4.1
3.3
30.93
31.86
u/l
0.14
461
3632
1189
11319
2.14
7.31
15.0
11.8
26.02
25.71
u/l
0.21
1171
11034
59
274
2.21
7.29
1.2
1.2
2.40
5.35
u/ml
—
5
20
501
4060
1.39
7.22
3.7
3.6
35.38
60.53
ng/l
0.64
311
2755
379
2928
1.42
7.20
2.8
2.2
2.46
2.82
mg/l
3.66
340
2520
122
734
1.73
7.09
3.0
3.0
145.53
171.13
ng/l
0.33
117
674
223
1566
1.52
6.89
3.1
2.5
23.01
23.11
%
0.04
200
1468
238
1703
1.49
6.71
3.1
2.5
2.37
2.34
g/l
0.49
216
1583
330
2525
1.42
6.51
1.9
1.7
1.25
1.13
mg/l
0.15
253
1939
252
1843
1.46
6.33
3.0
2.5
13.68
13.35
umol/l
0.31
230
1716
1215
11733
2.52
6.09
30.1
23.1
252.60
254.18
e9/l
0.41
1197
11535
139
902
1.61
6.06
3.6
2.6
10.43
10.87
g/l
0.49
132
832
1215
11735
2.52
6.05
30.0
23.0
91.18
90.93
fl
1.25
1207
11633
850
7615
1.37
6.01
3.8
3.3
44.35
45.72
u/l
0.19
807
7212
1215
11738
2.51
5.99
30.8
23.5
40.26
40.35
%
0.26
1207
11628
1215
11738
2.51
5.99
30.0
23.0
4.46
4.49
e12/l
1.29
1192
11512
242
1775
1.45
5.97
2.1
1.9
—
—
—
0
0
233
1697
1.46
5.96
1.8
1.7
1137.97
1207.26
nmol/l
0.62
179
1289
1215
11741
2.49
5.93
30.1
23.1
6.61
6.71
e9/l
0.87
1193
11507
36
148
2.48
5.90
1.2
1.4
—
—
—
0
0
1215
11743
2.49
5.89
30.2
23.2
134.80
135.02
g/l
0.23
1208
11638
1139
10788
1.66
5.84
6.2
5.6
2.73
2.74
mmol/l
0.05
1083
10122
87
503
1.78
5.82
2.2
2.2
37.30
39.45
u/l
0.60
80
458
60
308
2.00
5.77
2.3
2.5
10.05
11.86
mg/l
1.48
54
293
1100
10344
1.55
5.70
5.4
5.0
5.74
5.88
mmol/l
4.10
1042
9569
59
305
1.98
5.58
1.1
1.1
3.97
6.06
eliau/ml
—
9
42
356
2825
1.36
5.52
2.9
2.7
330.13
337.03
umol/l
0.59
319
2509
336
2642
1.37
5.52
4.4
3.9
1.02
1.59
kg/l
0.50
240
1756
180
1265
1.49
5.50
3.4
2.7
5.90
8.11
umol/l
2.15
156
1118
464
3846
1.33
5.35
3.0
3.5
2.35
2.35
mmol/l
0.84
426
3521
1124
10649
1.58
5.30
5.5
5.0
4.66
4.67
mmol/l
0.14
1073
10019
1120
10603
1.56
5.30
5.4
4.9
1.49
1.48
mmol/l
0.39
1064
9918
28
109
2.60
5.16
1.3
1.2
18.00
81.83
u/ml
—
5
6
612
5299
1.30
5.07
3.0
2.7
—
—
estimate
—
0
0
1098
10374
1.50
4.98
18.8
14.4
83.02
83.46
ml/min/173m2
0.29
1026
9551
45
222
2.07
4.86
7.0
6.9
105.00
105.40
mmol/l
0.28
40
204
96
602
1.64
4.83
10.6
11.0
16.08
15.84
%
0.37
91
582
375
3052
1.33
4.81
3.0
3.1
1019.86
1109.52
ng/l
0.23
328
2586
425
3528
1.31
4.72
4.3
3.2
29.84
73.10
e6/l
1.37
330
2691
76
453
1.72
4.63
4.9
1.4
20.20
12.65
iu/ml
—
10
12
125
844
1.53
4.61
1.3
1.3
292.48
201.00
u/ml
0.25
116
787
39
186
2.13
4.61
1.4
1.6
—
—
—
0
0
62
350
1.81
4.54
1.2
1.3
9.54
10.91
u/ml
0.06
11
53
62
351
1.81
4.50
1.2
1.2
4.64
2.57
u/ml
—
9
32
379
3125
1.31
4.36
1.9
1.7
21.76
20.52
nmol/l
0.88
332
2662
48
253
1.93
4.35
1.2
1.4
—
—
—
0
0
792
7175
1.29
4.30
3.5
3.2
—
—
—
0
0
537
4639
1.28
4.28
2.1
1.9
1.34
1.35
mmol/l
0.06
457
3948
135
943
1.48
4.25
8.0
7.5
9.53
9.27
mmol/l
0.16
130
910
61
351
1.78
4.22
3.4
2.7
—
—
—
0
0
80
501
1.64
4.08
1.6
1.8
4.59
7.73
iu/ml
0.80
18
112
71
431
1.69
4.08
1.9
1.7
—
—
—
0
0
18
63
2.88
4.07
1.4
1.7
—
—
—
0
0
1064
10069
1.39
4.06
6.5
6.1
38.37
38.95
mmol/mol
1.50
1015
9485
1066
10102
1.39
3.94
4.6
4.2
1.24
1.27
mmol/l
0.81
1004
9385
15
48
3.15
3.93
1.2
1.1
—
—
—
0
0
77
484
1.63
3.88
5.8
4.7
1.64
1.57
%
0.28
71
460
111
761
1.50
3.84
2.6
3.6
4.44
4.56
pmol/l
0.76
100
676
122
854
1.48
3.82
4.1
3.7
75.52
83.29
ng/l
0.80
106
760
282
2271
1.31
3.79
1.8
1.6
—
—
—
0
0
221
1719
1.35
3.77
3.8
2.9
2.54
2.74
e6/l
0.12
113
816
58
341
1.74
3.76
1.3
1.4
—
—
—
0
0
162
1200
1.40
3.74
5.1
4.7
237.38
245.07
u/l
0.25
157
1144
235
1850
1.33
3.70
4.3
3.2
0.82
0.82
mmol/l
0.06
226
1761
191
1457
1.37
3.70
7.8
5.5
1.03
1.03
mmol/l
0.02
181
1348
526
4591
1.25
3.68
4.7
3.7
4.59
0.03
estimate
0.49
109
1063
213
1655
1.35
3.66
2.4
2.1
30.14
29.42
s
0.51
206
1609
397
3358
1.27
3.62
4.3
3.2
0.09
0.05
estimate
0.19
115
1032
39
205
1.93
3.61
1.3
1.4
—
—
—
0
0
24
104
2.33
3.61
4.0
3.6
—
—
—
0
0
59
354
1.70
3.57
1.3
1.3
—
—
—
0
0
68
424
1.64
3.56
1.6
2.3
4.02
4.25
g/l
1.53
63
394
68
424
1.64
3.56
1.6
2.3
7.03
7.41
g/l
1.03
63
394
65
401
1.66
3.55
1.6
2.3
2.85
3.01
g/l
0.65
60
371
237
1883
1.32
3.49
3.5
2.8
0.89
1.04
e6/l
0.51
129
981
18
69
2.63
3.48
1.3
1.3
—
—
—
0
0
115
812
1.46
3.46
3.2
2.3
13.48
12.87
nmol/l
0.29
101
738
175
1331
1.37
3.45
2.1
1.8
—
—
—
0
0
142
1043
1.41
3.45
3.0
2.3
0.20
0.21
g/l
1.42
133
977
27
127
2.15
3.37
2.3
1.7
29.33
33.25
ng/l
0.15
27
127
167
1267
1.37
3.35
2.1
1.8
—
—
—
0
0
67
424
1.61
3.32
1.6
2.3
3.47
3.78
g/l
1.16
62
394
162
1228
1.37
3.27
9.4
8.4
13.46
12.29
kpa
1.79
154
1191
162
1228
1.37
3.27
9.4
8.4
5.11
5.11
kpa
0.02
153
1189
160
1213
1.37
3.22
9.1
8.4
0.87
0.98
mmol/l
0.13
132
1017
90
617
1.49
3.15
1.1
1.0
—
—
—
0
0
76
503
1.54
3.14
1.9
1.6
0.43
0.33
mg/l
0.59
40
227
121
880
1.42
3.12
2.1
2.8
65.63
66.72
g/l
0.63
115
820
59
368
1.63
3.12
1.6
2.3
10.18
10.60
g/l
0.29
54
337
33
173
1.93
3.11
1.1
1.4
—
—
—
0
0
118
857
1.42
3.07
1.5
1.4
—
—
—
0
0
60
378
1.62
3.05
2.0
1.9
—
—
—
0
0
84
574
1.50
3.00
3.3
3.5
1.16
1.87
mmol/l
1.18
67
437
292
2430
1.26
2.99
1.6
1.5
2.34
2.40
g/l
0.21
181
1519
47
281
1.70
2.93
1.3
1.6
—
—
—
0
0
12
39
3.10
2.77
39.5
32.7
120.75
120.84
ug/l
0.00
12
31
166
1296
1.32
2.77
4.9
4.7
33.63
32.14
%
1.17
128
872
87
610
1.46
2.76
2.0
1.6
—
—
—
0
0
354
3035
1.23
2.75
4.2
3.1
0.26
0.43
e6/l
1.71
259
2216
48
294
1.66
2.75
1.3
1.6
—
—
—
0
0
55
349
1.60
2.75
2.0
1.8
—
—
—
0
0
253
2092
1.26
2.72
1.7
1.5
—
—
—
0
0
68
455
1.52
2.71
1.8
2.0
1.49
1.54
g/l
0.14
57
403
290
2447
1.24
2.60
3.3
2.6
6.08
6.71
e6/l
0.19
272
2240
57
372
1.56
2.55
1.7
1.5
0.03
0.07
iu/ml
—
10
56
12
44
2.74
2.55
1.2
1.2
85.00
87.15
%
—
5
27
48
304
1.60
2.44
1.1
1.2
—
—
—
0
0
78
550
1.45
2.43
2.2
2.2
5944.91
5596.89
u/l
0.04
21
235
26
138
1.90
2.42
1.5
1.6
—
—
—
0
0
30
167
1.82
2.42
1.1
1.1
2.19
1.69
eliau/ml
0.21
14
80
26
139
1.89
2.37
1.8
1.5
275.19
278.20
mosm/kgh2o
0.28
21
106
325
2803
1.22
2.35
6.3
5.3
2.24
2.61
ug/l
0.44
303
2533
140
1095
1.31
2.33
4.1
4.4
5.63
21.33
ug/l
1.31
105
900
38
230
1.67
2.32
1.1
1.1
6.86
5.35
u/ml
0.17
25
125
88
641
1.40
2.31
11.4
10.8
24.22
24.38
mmol/l
0.16
88
633
10
34
2.96
2.28
2.5
1.6
121.40
96.29
nmol/24h
—
10
34
39
239
1.65
2.28
5.1
5.9
203.40
334.93
iu/ml
—
10
29
56
377
1.51
2.21
1.8
2.5
0.67
1.08
g/l
0.33
50
333
131
1023
1.31
2.21
10.7
9.2
121.74
120.71
g/l
0.23
125
1003
269
2290
1.22
2.21
1.7
1.7
133333767.56
36861554.31
pmol/l
0.65
225
1937
322
2794
1.21
2.17
5.6
3.9
92.52
91.15
%
0.45
310
2734
37
227
1.65
2.16
1.6
1.6
—
—
—
0
0
40
251
1.61
2.14
1.4
1.6
—
—
—
0
0
11
42
2.63
2.14
6.3
4.4
—
—
—
0
0
36
220
1.66
2.14
1.2
1.4
—
—
—
0
0
317
2752
1.20
2.12
2.9
2.3
—
—
—
0
0
69
491
1.43
2.08
1.9
1.6
319.86
283.75
mu/l
0.42
61
445
0
56
0.00
2.06
0.0
2.8
—
1.26
—
0
56
48
320
1.52
2.01
2.6
1.7
36.94
42.12
nmol/l
0.48
48
308
115
896
1.31
1.99
1.2
1.2
131.08
134.57
u/ml
0.04
62
367
14
284
0.49
1.99
3.3
3.9
3.89
3.87
mmol/l
0.06
14
279
33
202
1.65
1.97
1.4
1.3
18.13
23.72
u/l
0.60
23
167
137
1095
1.28
1.96
9.8
8.7
96.05
95.67
%
0.32
129
1061
11
45
2.46
1.93
1.3
1.7
87.80
88.64
%
—
5
28
21
113
1.87
1.92
1.1
1.6
—
—
—
0
0
54
374
1.46
1.90
1.5
1.4
—
—
—
0
0
30
181
1.67
1.89
1.1
1.1
1.12
5.16
u/ml
2.37
15
75
7
22
3.19
1.88
1.0
1.1
—
—
—
0
0
12
52
2.32
1.88
1.2
1.4
—
—
—
0
0
12
52
2.32
1.88
1.2
1.4
—
—
—
0
0
956
9160
1.19
1.82
24.9
18.5
13.49
13.56
%
0.98
946
9049
92
1180
0.76
1.75
5.1
6.8
—
—
—
0
0
19
103
1.86
1.72
1.0
1.1
—
—
—
0
0
35
226
1.56
1.72
1.1
1.1
32.74
17.99
au/ml
—
8
68
35
226
1.56
1.72
1.5
1.4
—
—
—
0
0
259
2251
1.19
1.70
5.2
4.4
22.28
21.55
%
0.34
133
1058
24
141
1.72
1.69
1.3
1.2
—
—
—
0
0
6
19
3.17
1.66
1.0
1.1
101.50
98.95
%
—
6
19
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
47
327
1.45
1.65
3.9
3.1
0.32
0.39
iu/ml
1.32
29
179
15
76
1.99
1.64
1.0
1.1
—
—
—
0
0
29
181
1.62
1.64
1.2
1.2
3.27
5.82
u/ml
0.54
11
76
11
49
2.26
1.64
1.1
1.4
178.36
177.58
mmol/24h
0.01
11
49
12
56
2.15
1.61
1.0
1.4
—
—
—
0
0
12
56
2.15
1.61
1.0
1.4
—
—
—
0
0
31
198
1.58
1.61
1.1
1.1
3.80
4.80
u/ml
0.13
17
98
47
330
1.44
1.58
3.0
3.7
4.29
3.45
ratio
0.10
26
192
7
26
2.70
1.58
1.0
1.2
—
—
—
0
0
29
444
0.64
1.55
1.0
1.1
1.62
1.55
g/l
0.69
29
444
39
265
1.49
1.55
1.3
1.1
5.18
2.71
u/ml
0.34
27
143
130
1067
1.24
1.53
3.1
2.3
42.86
38.16
u/l
0.24
109
890
5
15
3.34
1.52
1.0
1.0
0.01
0.11
u/ml
—
5
10
5
15
3.34
1.52
1.0
1.5
—
—
—
0
0
65
487
1.35
1.52
1.2
1.2
0.18
1.11
u/ml
—
5
30
49
353
1.40
1.45
1.6
1.3
7.12
10.09
u/l
1.81
42
289
37
255
1.46
1.39
2.4
2.2
132.88
129.04
g/l
0.48
25
211
42
297
1.43
1.39
1.3
1.2
35.26
57.06
u/ml
—
5
29
247
2176
1.17
1.39
2.7
2.9
2.43
2.45
mmol/l
1.78
223
1962
48
348
1.39
1.38
4.0
2.9
1.62
1.47
mg/l
0.41
42
314
12
60
2.01
1.38
1.8
1.4
15.58
13.74
u/l
0.26
12
54
33
223
1.49
1.37
1.2
1.1
1.33
2.00
u/ml
0.30
19
113
73
568
1.30
1.34
1.4
1.4
—
—
—
0
0
20
120
1.68
1.34
1.1
1.1
—
—
—
0
0
77
604
1.29
1.34
1.5
1.4
—
—
—
0
0
40
284
1.42
1.31
1.5
1.6
4948.24
13123.23
e6/l
1.76
25
206
6
24
2.51
1.30
1.0
1.2
—
—
—
0
0
35
243
1.45
1.29
3.0
1.8
181.74
205.98
pmol/l
0.84
35
229
28
186
1.52
1.27
1.1
1.3
—
—
—
0
0
8
35
2.29
1.27
1.6
1.4
—
—
—
0
0
362
3304
1.13
1.24
5.3
3.9
0.00
0.01
estimate
1.34
124
1190
9
45
2.01
1.23
1.4
2.1
—
—
—
0
0
177
1535
1.18
1.22
2.5
2.3
—
—
—
0
0
19
116
1.65
1.21
1.2
1.6
52.38
59.00
%
0.36
13
81
5
19
2.64
1.21
1.0
1.3
—
—
—
0
0
49
367
1.35
1.19
2.8
2.1
96.53
92.34
%
0.73
49
356
12
64
1.88
1.18
1.8
3.3
1428.00
1304.69
u/ml
0.05
12
64
13
224
0.58
1.18
2.8
3.5
12.50
24.82
mg/l
—
7
152
10
50
2.01
1.16
1.2
1.9
—
—
—
0
0
10
50
2.01
1.16
1.2
1.9
—
—
—
0
0
10
50
2.01
1.16
1.2
1.9
—
—
—
0
0
10
50
2.01
1.16
1.2
1.9
—
—
—
0
0
33
459
0.71
1.14
1.2
1.2
0.85
0.89
g/l
0.46
33
459
27
183
1.49
1.14
1.4
1.8
—
—
—
0
0
48
364
1.33
1.09
3.1
2.5
24.23
25.00
mmol/l
0.67
48
358
163
1419
1.17
1.08
2.3
2.1
—
—
—
0
0
13
74
1.76
1.07
1.3
1.4
—
—
—
0
0
79
643
1.24
1.06
6.8
3.2
24.54
24.30
mmol/l
0.36
79
635
36
263
1.38
1.04
1.2
1.4
8.92
15.15
e6/l
0.42
26
197
9
46
1.96
1.03
1.0
1.4
—
—
—
0
0
9
46
1.96
1.03
1.0
1.4
—
—
—
0
0
25
171
1.47
1.02
1.9
2.1
2.62
5.23
umol/l
3.64
18
124
407
3785
1.11
0.99
3.7
3.4
7.11
7.63
mmol/l
1.63
346
3230
82
677
1.23
0.98
1.3
1.4
22.16
26.42
iu/l
0.65
74
583
41
310
1.33
0.97
1.1
1.1
—
—
—
0
0
7
36
1.95
0.97
1.3
2.1
—
—
—
0
0
7
36
1.95
0.97
1.3
2.1
—
—
—
0
0
55
434
1.28
0.97
1.5
1.3
215.23
253.74
miu/ml
0.39
30
212
95
798
1.21
0.96
1.9
2.4
5.53
7.02
ug/l
0.56
84
717
26
182
1.44
0.96
1.2
1.2
2.67
2.82
u/ml
—
9
61
122
1049
1.18
0.96
5.6
3.3
1.98
1.92
mmol/l
0.06
110
898
21
141
1.50
0.95
1.9
1.9
32.19
32.45
pg
0.08
21
141
36
268
1.35
0.95
1.2
1.5
1162.79
560.93
e6/l
0.20
29
209
41
312
1.32
0.94
1.1
1.2
—
—
—
0
0
11
62
1.78
0.94
1.4
1.5
—
—
—
0
0
7
37
1.90
0.94
1.3
2.1
—
—
—
0
0
25
175
1.44
0.93
1.0
1.1
—
—
—
0
0
9
52
1.74
0.92
1.3
1.3
160.07
173.49
pmol/l
—
9
52
24
167
1.45
0.92
1.0
1.1
118.92
114.63
%
0.30
24
154
15
94
1.60
0.90
1.2
1.1
279.53
290.46
mg/l
0.32
15
85
941
9158
1.11
0.89
25.2
19.3
332.48
332.23
g/l
0.39
935
9115
55
443
1.25
0.85
1.5
1.6
8.95
11.47
u/ml
—
10
106
24
171
1.41
0.83
1.0
1.0
0.02
0.40
u/ml
—
9
58
40
310
1.30
0.83
1.6
1.6
—
—
—
0
0
8
46
1.74
0.82
1.0
1.1
—
—
—
0
0
11
65
1.70
0.82
1.5
1.2
10.27
11.73
u/l
0.21
11
56
14
89
1.58
0.81
1.1
1.5
—
—
—
0
0
14
89
1.58
0.81
4.5
2.7
—
—
—
0
0
19
130
1.47
0.81
1.1
1.1
100.00
96.70
%
0.22
19
119
187
1685
1.13
0.80
3.5
3.2
0.67
0.73
ug/l
0.72
137
1064
17
114
1.50
0.79
1.4
1.2
—
—
—
0
0
11
66
1.67
0.78
1.2
1.1
1.08
1.07
ratio
0.22
11
57
19
131
1.46
0.78
1.2
1.1
—
—
—
0
0
18
123
1.47
0.77
3.1
2.6
14.50
19.95
mg/l
—
8
53
25
184
1.37
0.74
2.8
3.4
0.86
0.81
nmol/l
0.16
16
152
16
108
1.49
0.73
1.3
1.2
—
—
—
0
0
7
38
1.85
0.73
1.0
1.8
37.21
40.99
g/l
—
7
38
11
68
1.62
0.71
1.2
1.2
—
—
—
0
0
15
101
1.49
0.70
1.1
1.0
—
—
—
0
0
7
41
1.71
0.70
1.6
1.8
45.96
52.68
ug/l
—
7
41
14
93
1.51
0.69
1.4
1.2
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
14
94
1.49
0.67
1.4
1.1
—
—
—
0
0
5
28
1.79
0.66
1.6
3.5
7.40
5.21
ug/l
—
5
28
10
62
1.62
0.65
1.4
1.5
—
—
—
0
0
121
1080
1.13
0.63
3.2
3.2
—
—
—
0
0
154
1396
1.12
0.62
1.7
1.8
1.41
1.44
%
0.36
134
1227
8
49
1.64
0.62
1.5
1.6
0.45
0.49
e9/l
—
8
49
14
96
1.46
0.61
1.4
1.1
—
—
—
0
0
14
96
1.46
0.61
1.4
1.1
—
—
—
0
0
37
301
1.24
0.57
1.4
1.3
—
—
—
0
0
10
65
1.54
0.55
1.4
1.5
—
455.00
—
0
6
13
90
1.45
0.55
1.3
1.6
—
—
—
0
0
13
90
1.45
0.55
1.3
1.6
—
—
—
0
0
13
90
1.45
0.55
1.3
1.6
—
—
—
0
0
75
655
1.15
0.55
6.8
6.5
24.94
24.51
mmol/l
0.58
68
626
374
3555
1.07
0.55
4.7
4.1
9.06
8.38
mg/mmol
0.09
223
2215
13
91
1.43
0.53
1.5
1.3
201.25
400.30
u/l
0.98
13
86
46
387
1.20
0.53
1.8
1.6
1.12
1.18
g/l
0.93
46
368
19
143
1.33
0.52
1.5
1.5
—
—
—
0
0
6
97
0.62
0.52
1.3
1.6
—
—
—
0
0
12
83
1.45
0.52
1.7
1.6
—
—
—
0
0
36
434
0.82
0.51
2.7
1.8
1.11
2.04
ug/l
0.41
30
392
85
953
0.88
0.50
1.6
1.7
3.51
3.48
mmol/l
0.09
56
665
22
172
1.28
0.48
1.8
1.4
—
—
—
0
0
27
217
1.25
0.48
1.9
1.4
176.91
158.10
au/ml
0.42
11
64
14
102
1.38
0.47
1.4
1.1
—
—
—
0
0
18
137
1.32
0.47
1.1
1.2
—
—
—
0
0
29
237
1.23
0.45
1.5
1.2
300.86
249.80
u/ml
0.30
14
138
5
85
0.59
0.45
2.0
2.0
4.40
2.06
u/field
—
5
50
52
451
1.16
0.44
1.7
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
0.87
—
0
15
41
352
1.17
0.40
2.0
2.1
2.06
4.13
iu/l
3.26
22
148
117
1270
0.91
0.40
1.7
1.9
3.33
3.45
ratio
0.49
83
974
0
18
0.00
0.40
0.0
1.8
—
1.23
—
0
18
42
362
1.17
0.40
1.4
1.4
—
—
—
0
0
5
35
1.43
0.39
1.4
2.3
11.52
16.51
umol/l
—
5
35
0
19
0.00
0.39
0.0
7.9
—
10.51
—
0
19
9
66
1.37
0.38
2.6
1.5
109.78
90.47
ng/l
—
9
66
95
868
1.10
0.38
2.0
2.5
74.18
69.15
ml/min/173m2
0.61
45
376
15
192
0.78
0.38
1.1
1.1
8.20
149.37
iu/ml
—
5
46
17
134
1.27
0.37
1.8
1.5
—
—
—
0
0
17
134
1.27
0.37
1.8
1.5
—
—
—
0
0
5
79
0.63
0.35
1.0
1.4
107.40
76.01
umol/l
—
5
79
17
135
1.26
0.35
1.8
1.5
—
—
—
0
0
45
395
1.14
0.35
1.4
1.6
63.51
58.93
ug/l
0.25
38
333
42
367
1.15
0.35
1.4
1.5
1.05
1.11
ratio
0.22
30
228
42
367
1.15
0.35
1.4
1.5
0.92
0.96
ratio
0.30
30
228
42
367
1.15
0.35
1.4
1.5
1.03
1.19
ratio
0.72
30
228
13
100
1.30
0.33
1.1
1.2
115.15
112.30
pmol/l
0.10
13
100
12
92
1.31
0.32
1.2
1.5
—
—
—
0
0
13
101
1.29
0.31
1.8
1.9
—
—
—
0
0
17
138
1.24
0.30
1.8
1.5
—
—
—
0
0
103
959
1.08
0.29
2.4
2.1
—
—
—
0
0
38
429
0.88
0.29
1.5
1.4
—
—
—
0
0
8
62
1.29
0.28
1.4
1.1
—
—
—
0
0
17
140
1.22
0.27
1.8
1.5
—
—
—
0
0
17
140
1.22
0.27
1.8
1.5
—
—
—
0
0
24
205
1.17
0.27
1.6
1.3
—
—
—
0
0
24
205
1.17
0.27
1.6
1.3
—
—
—
0
0
8
64
1.25
0.27
1.4
2.1
—
—
—
0
0
14
113
1.24
0.26
1.8
1.8
—
—
—
0
0
18
213
0.84
0.25
2.9
3.1
6.99
7.52
mmol/l
0.46
18
204
23
266
0.86
0.25
1.6
1.5
56.74
58.35
ug/l
0.07
23
266
6
84
0.71
0.24
2.0
1.6
—
—
—
0
0
6
84
0.71
0.24
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
5
38
1.32
0.23
1.8
1.7
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
85
798
1.07
0.22
2.4
2.0
—
—
—
0
0
5
42
1.19
0.21
2.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
16
188
0.85
0.21
1.3
1.3
—
—
—
0
0
12
98
1.23
0.21
1.3
1.1
16.58
16.67
u/ml
—
5
49
5
43
1.16
0.21
1.4
1.3
—
—
—
0
0
41
448
0.91
0.20
1.5
1.9
2.77
4.98
mg/l
0.88
29
329
66
702
0.94
0.18
14.1
10.5
1.08
1.28
%
1.87
66
695
27
297
0.91
0.15
1.4
1.2
—
—
—
0
0
29
316
0.92
0.14
2.1
1.7
—
—
—
0
0
22
241
0.91
0.12
2.0
2.4
7.53
80.91
ug/min
4.30
12
146
68
711
0.95
0.12
1.5
1.6
871.05
1007.28
mu/l
0.79
52
594
17
153
1.11
0.11
1.1
1.1
—
—
—
0
0
33
350
0.94
0.09
1.6
1.6
—
—
—
0
0
5
48
1.04
0.09
1.2
1.1
85.16
153.65
iu/ml
—
5
48
54
517
1.05
0.09
3.1
3.3
1.02
1.02
ratio
0.39
49
484
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
64
1.09
0.08
1.1
1.1
—
—
—
0
0
7
64
1.09
0.08
1.1
1.1
—
—
—
0
0
10
88
1.14
0.08
1.8
1.2
—
—
—
0
0
27
287
0.94
0.08
5.1
3.2
1.70
2.20
index
—
10
150
7
65
1.08
0.08
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
1.3
1.2
8.29
9.46
mm/h
—
7
68
6
71
0.84
0.07
1.0
1.3
—
—
—
0
0
6
74
0.81
0.07
14.2
13.2
0.64
0.64
mmol/l
—
6
69
8
76
1.05
0.07
3.0
2.2
—
—
—
0
0
65
671
0.97
0.07
15.0
10.9
0.56
0.64
%
1.07
65
665
7
85
0.82
0.07
1.4
1.6
14.29
11.43
umol/l
—
7
79
10
89
1.12
0.07
1.8
1.2
—
—
—
0
0
48
463
1.04
0.06
1.3
1.4
—
—
—
0
0
10
111
0.90
0.06
1.4
1.3
6.61
6.58
mmol/l
—
10
102
27
261
1.04
0.02
2.4
2.9
1.39
1.53
mmol/l
0.58
27
251
69
692
1.00
0.00
14.3
10.8
94.78
93.82
%
1.10
69
687
12
117
1.03
0.00
1.2
2.0
92.10
90.06
%
0.96
12
117
85
855
0.99
0.00
4.3
3.8
1.23
1.23
mmol/l
0.08
74
731
6
64
0.94
0.00
1.0
1.1
1922.00
1515.59
miu/ml
—
6
64
6
64
0.94
0.00
1.2
1.5
—
964639.80
—
0
5
0
6
0.00
0.00
0.0
6.5
—
—
—
0
0
7
77
0.91
-0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
2.0
1.5
1.80
5.38
u/field
—
5
45
9
89
1.01
-0.00
1.0
1.1
—
2.86
nmol/l
—
0
17
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
1.75
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EUSTNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EUSTNAS | 1.042 [0.88, 1.23] | 0.633 |
| Birth year | 0.993 [0.98, 1.0] | 0.101 |
During the follow-up period (1.1.1998 — 31.12.2019), 209 out of 2905 females with H8_EUSTNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EUSTNAS | 1.333 [1.11, 1.6] | 0.002 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 270 out of 1926 males with H8_EUSTNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EUSTNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.267% |
| 5 | 0.58% | 1.539% |
| 10 | 1.468% | 3.684% |
| 15 | 2.676% | 6.729% |
| 20 | 4.803% | 11.652% |
Relationships between endpoints
↥Index endpoint: H8_EUSTNAS – Other disorders of Eustachian tube
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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