No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
90 |
4. Check minimum number of eventsNone |
90 |
5. Include endpointsNone |
90 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Multiple congenital exostoses
based on the number of shared cases.
Similar with more cases:
- Multiple congenital exostoses, including avohilmo
- Other osteochondrodysplasias
- Other osteochondrodysplasias, including avohilmo
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations and deformations of the musculoskeletal system, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 42 | 38 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 27.54 | 21.99 | 33.67 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 85
- Matched controls
- 850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q78.6
ICD-10 Finland
Multiple congenital exostoses
+∞
119.4
84
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
151.4
12.8
13
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
62.4
9.9
11
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
27.6
9.2
12
5
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
+∞
7.4
7
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
+∞
7.4
7
*
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
75.3
6.5
7
*
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
+∞
6.3
6
*
75665
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Exostosis cartilaginea multiplex
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
29
166
2.13
2.59
2.4
2.3
—
—
—
0
0
18
84
2.45
2.57
2.6
2.5
0.50
3.36
e6/l
—
8
42
38
258
1.86
2.02
4.9
5.3
36.02
37.51
g/l
0.96
38
247
6
16
3.95
1.97
1.0
1.3
—
—
—
0
0
19
103
2.09
1.91
2.7
2.4
0.68
1.09
e6/l
—
9
60
46
336
1.80
1.90
2.9
2.8
—
—
estimate
—
0
0
15
77
2.15
1.72
8.8
9.7
102.40
104.26
mmol/l
0.49
15
77
6
19
3.32
1.69
1.0
1.2
—
—
—
0
0
7
26
2.84
1.62
4.0
17.9
24.29
23.89
mmol/l
—
7
26
36
255
1.71
1.58
1.9
1.8
104.41
96.51
pmol/l
0.35
18
139
16
91
1.93
1.41
1.5
2.3
28.48
29.14
s
0.20
16
91
16
99
1.76
1.09
3.3
2.6
2.45
2.41
mmol/l
0.49
16
89
24
169
1.59
1.03
2.1
2.0
198.75
200.74
u/l
0.01
24
163
75
681
1.86
1.02
17.1
10.6
92.31
93.22
ml/min/173m2
0.12
68
622
19
131
1.58
0.88
1.4
1.3
10.60
26.46
iu/ml
—
5
39
26
195
1.48
0.83
4.5
3.0
0.00
0.02
estimate
—
8
66
36
289
1.43
0.81
3.6
2.7
0.00
0.00
estimate
—
6
59
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
45
381
1.38
0.73
3.6
2.9
0.00
0.00
estimate
—
8
68
45
381
1.38
0.73
3.6
2.8
0.00
0.00
estimate
—
7
71
21
155
1.47
0.72
2.1
1.5
18.23
21.01
nmol/l
0.55
21
137
5
28
1.83
0.67
3.0
1.2
—
—
—
0
0
45
386
1.35
0.65
3.7
3.0
0.00
0.00
estimate
—
7
66
16
114
1.50
0.65
3.6
3.5
2527.74
705.86
ng/l
0.45
16
85
63
570
1.41
0.64
5.0
4.1
14.57
14.64
pmol/l
0.09
57
528
22
169
1.41
0.61
5.1
2.8
1.02
1.02
kg/l
0.11
14
108
0
20
0.00
0.61
0.0
1.7
—
—
—
0
0
22
172
1.38
0.56
3.2
2.6
0.10
0.22
e6/l
0.65
16
132
6
38
1.62
0.55
2.5
1.5
—
—
—
0
0
15
110
1.44
0.53
5.1
3.8
0.76
0.81
mmol/l
0.94
15
104
7
45
1.60
0.50
1.1
1.1
1.08
0.90
g/l
—
7
45
7
45
1.60
0.50
1.1
1.1
1.43
1.60
g/l
—
7
45
7
48
1.50
0.48
1.4
4.7
4.17
4.58
pmol/l
—
7
43
8
55
1.50
0.44
2.7
2.7
—
—
—
0
0
8
56
1.47
0.44
2.5
2.3
28.00
32.78
u/l
—
8
46
13
97
1.40
0.42
1.6
1.6
—
—
—
0
0
5
33
1.55
0.42
1.4
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
80
773
1.59
0.37
21.6
13.9
74.50
73.56
umol/l
0.13
80
764
6
87
0.67
0.35
1.3
1.9
3.95
3.36
mmol/l
—
6
60
7
53
1.35
0.32
2.4
1.5
240.00
317.96
mu/l
—
7
46
46
421
1.20
0.31
13.2
8.9
3.87
4.04
e9/l
0.29
40
373
8
108
0.71
0.31
1.6
2.0
3.56
3.43
ratio
—
8
82
14
112
1.30
0.30
4.5
2.7
1.03
0.85
ug/l
—
8
60
7
56
1.27
0.30
1.0
1.5
—
—
—
0
0
23
197
1.23
0.30
1.9
2.3
—
—
—
0
0
9
75
1.22
0.26
1.2
1.4
—
—
—
0
0
5
38
1.34
0.23
3.6
7.3
25.48
24.93
mmol/l
—
5
38
11
89
1.27
0.22
2.3
2.1
—
—
—
0
0
21
184
1.19
0.22
1.9
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
205.66
—
0
12
0
12
0.00
0.21
0.0
1.3
—
1.14
—
0
7
40
371
1.15
0.20
2.5
3.1
82.99
90.23
ug/l
0.19
40
359
21
185
1.18
0.20
4.2
3.8
11.87
12.49
mg/mmol
0.03
14
124
13
109
1.23
0.20
1.7
1.7
700000337.00
119388207.98
pmol/l
0.37
13
98
9
78
1.17
0.16
1.2
1.3
—
—
—
0
0
63
614
1.10
0.09
3.5
3.8
—
—
—
0
0
7
64
1.10
0.08
8.4
6.5
—
—
—
0
0
24
226
1.09
0.07
4.7
3.2
38.52
19.27
ng/l
0.66
16
121
69
677
1.10
0.07
19.7
14.9
332.09
334.37
g/l
1.44
69
677
12
109
1.12
0.06
2.7
2.1
—
—
—
0
0
72
712
1.07
0.03
20.5
13.4
3.96
3.94
mmol/l
0.25
72
699
13
137
0.94
0.01
1.6
1.6
—
—
—
0
0
14
146
0.95
0.00
5.3
3.8
22.52
23.48
%
—
5
63
21
212
0.99
0.00
3.6
2.6
52.10
73.23
u/l
0.52
21
201
22
218
1.01
0.00
1.8
1.9
—
—
—
0
0
21
209
1.01
0.00
2.8
2.3
0.00
0.00
estimate
—
6
57
73
734
0.96
0.00
19.0
11.8
25.76
22.87
mg/l
0.27
61
589
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
1.10
—
0
8
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
129.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.8
—
105.50
—
0
8
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
105.80
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
58
0.85
-0.00
4.6
3.5
5.70
5.72
kpa
—
5
58
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_MULTIPLE_CONGENITAL_EXOSTOSES – Multiple congenital exostoses
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).