No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
605 |
4. Check minimum number of eventsNone |
605 |
5. Include endpointsNone |
605 |
6. Filter based on genotype QC (FinnGen only) |
536 |
Control definitions (FinnGen only)
- Control exclude
- G6_CPETAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified paralytic syndromes
based on the number of shared cases.
Similar with more cases:
- Cerebral palsy and other paralytic syndromes
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5694 | 2528 | 3080 |
| Only index persons | 4141 | 1913 | 2228 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.07 | 0.09 |
| Only index persons | 0.08 | 0.07 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 46.76 | 48.42 | 45.00 |
| Only index persons | 38.07 | 42.26 | 34.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 536 | 295 | 241 |
| Unadjusted period prevalence (%) | 0.11 | 0.10 | 0.11 |
| Median age at first event (years) | 49.18 | 44.96 | 54.35 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 557
- Matched controls
- 5570
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G83.9
ICD-10 Finland
Paralytic syndrome, unspecified
2078.5
268.7
239
*
G83.8
ICD-10 Finland
Other specified paralytic syndromes
+∞
167.4
152
*
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
+∞
91.2
85
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.7
67.8
94
127
34409
ICD-8 Finland
Other cerebral paralysis, Unspecified
+∞
67.1
63
*
AA1AD
NOMESCO Finland
CT of head and brain
4.1
59.2
274
1065
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.7
53.4
115
244
N03AX14
ATC
levetiracetam; systemic
10.8
50.6
57
58
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
11.8
46.6
49
45
N18
ICPC
Paralysis/weakness
15.7
46.4
41
28
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.1
42.4
60
82
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
39.3
166
582
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.2
39.2
72
130
G81.9
ICD-10 Finland
Hemiplegia, unspecified
403.8
38.5
38
*
R4120
NOMESCO Finland
Occupational therapy
5.3
38.3
85
183
A28
ICPC
Limited function/disability NOS
3.5
37.4
165
593
L28
ICPC
Limited function/disability (L)
3.5
37.0
169
620
N03AF02
ATC
oxcarbazepine; oral
7.7
36.7
54
77
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
9.9
33.1
39
42
3449X
ICD-9 Finland
Other paralytic syndromes, Paralysis, unspecified
+∞
31.6
30
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.9
30.5
103
306
N03AX12
ATC
[U] gabapentin; oral
3.3
30.5
142
521
N03AG01
ATC
valproic acid; systemic, rectal
4.7
30.2
77
185
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
4.4
30.1
84
217
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.8
29.7
103
312
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.0
29.6
55
100
N28
ICPC
Limited function/disability (N)
11.7
28.7
30
27
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
28.3
139
524
R4110
NOMESCO Finland
Physiotherapy
2.8
28.1
211
1005
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.8
27.5
93
276
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.9
27.5
92
271
XA800
NOMESCO Finland
Neuropsychological investigation
5.4
26.4
55
111
R51.80
ICD-10 Finland
Headache
3.0
26.3
148
601
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.9
26.0
33
39
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
26.0
96
302
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
10.1
24.3
28
29
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.0
23.9
75
210
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
90.8
23.9
26
*
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
23.6
124
482
N05AA02
ATC
levomepromazine; systemic
5.3
23.2
49
100
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.1
23.1
114
427
R20.2
ICD-10 Finland
Paraesthesia of skin
3.9
22.7
74
213
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.3
22.6
62
157
TAB00
NOMESCO Finland
Lumbar puncture
4.7
22.3
55
128
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.1
22.3
40
70
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.9
22.1
41
74
N03AX16
ATC
[U] pregabalin
2.6
22.0
166
778
R52.2
ICD-10 Finland
Other chronic pain
5.0
21.7
49
106
R42
ICD-10 Finland
Dizziness and giddiness
2.6
21.6
169
805
N03AF01
ATC
carbamazepine; oral, rectal
4.5
21.5
55
132
Z3226
NOMESCO Finland
Physiotherapist
2.7
20.9
135
584
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.8
20.4
125
525
SPAT1229
SPAT
Assessment of need for aid
4.0
20.4
63
174
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
19.7
121
509
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.0
19.5
58
156
K90
ICPC
Stroke/cerebrovascular accident
6.8
19.4
31
48
N03AX09
ATC
lamotrigine; oral
4.1
19.4
57
152
R11
ICD-10 Finland
Nausea and vomiting
3.2
18.7
83
291
A06AD11
ATC
lactulose; oral
2.8
18.6
108
440
N05AH04
ATC
quetiapine; oral
2.5
18.5
141
658
N02AA05
ATC
oxycodone; systemic
2.6
18.4
133
604
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.1
17.8
52
138
N03AE01
ATC
clonazepam; systemic
3.9
17.7
54
148
N05CD07
ATC
temazepam; oral
2.9
17.5
90
343
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
17.4
211
1200
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.3
17.1
70
233
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
17.1
162
831
TKC20
NOMESCO Finland
Catheterisation of bladder
3.5
16.6
62
195
Z2445
NOMESCO Finland
Psychologist
4.2
16.5
45
113
R53
ICD-10 Finland
Malaise and fatigue
2.2
16.5
185
1015
N05BA01
ATC
diazepam; systemic, rectal
2.7
16.5
102
428
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
16.4
189
1049
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
6.2
16.2
28
47
UKC02
NOMESCO Finland
Cystoscopy
2.6
16.1
109
477
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
6.4
16.1
27
44
N06AB04
ATC
citalopram; systemic
2.3
16.0
145
726
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
15.1
16.0
26
18
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
15.6
100
426
M03BX01
ATC
baclofen; systemic
6.4
15.6
26
42
G83.4
ICD-10 Finland
Cauda equina syndrome
164.4
15.6
16
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.8
15.5
50
142
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
15.4
150
774
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
15.3
112
508
U05
ICPC
Urination problems other
3.8
15.3
48
134
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
15.2
60
195
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
5.0
15.1
33
69
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
4.8
15.1
35
77
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
6.5
15.1
25
40
N02AX02
ATC
tramadol; systemic, rectal
2.0
15.1
266
1721
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.7
15.1
50
145
L17
ICPC
Foot/toe symptom/complaint
2.1
14.6
195
1137
S06.0
ICD-10 Finland
Concussion
2.7
14.6
90
376
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.5
14.5
52
159
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
14.4
225
1389
W19
ICD-10 Finland
Unspecified fall
2.8
14.2
76
295
Z2446
NOMESCO Finland
Social worker
3.2
14.1
60
204
A04
ICPC
Weakness/tiredness general
2.4
14.1
112
527
A29
ICPC
General symptom/complaint other
2.5
14.0
103
468
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.7
13.9
81
328
R33
ICD-10 Finland
Retention of urine
3.0
13.9
64
228
R4190
NOMESCO Finland
Nutritional therapy
3.9
13.9
42
114
N05AH03
ATC
olanzapine; systemic
3.2
13.8
59
201
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.5
13.7
49
149
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.9
13.7
68
253
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
13.6
230
1452
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
13.5
73
284
N06AX11
ATC
mirtazapine; oral
2.0
13.5
220
1371
N05AF03
ATC
chlorprothixene; systemic
4.8
13.5
31
68
WX892
NOMESCO Finland
Monitored bed care
3.1
13.3
60
211
U07
ICPC
Urine symptom/complaint other
3.0
13.3
63
228
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
13.2
282
1922
R52.9
ICD-10 Finland
Pain, unspecified
2.6
13.1
83
350
N02BF01
ATC
gabapentin; oral
2.7
13.1
78
319
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.2
13.1
36
91
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
13.0
214
1333
H53.2
ICD-10 Finland
Diplopia
4.5
13.0
32
74
N06AX16
ATC
venlafaxine; oral
2.4
13.0
103
483
G44.2
ICD-10 Finland
Tension-type headache
2.4
13.0
101
470
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.4
12.9
48
150
Z02.7
ICD-10 Finland
Issue of medical certificate
2.9
12.8
62
227
R1250
NOMESCO Finland
Evaluation of functional capability
5.1
12.8
27
55
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
12.7
119
599
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.5
12.6
45
137
A03FA01
ATC
metoclopramide; systemic, rectal
2.1
12.5
146
802
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
132.9
12.5
13
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
12.0
12.4
22
19
F61.0
ICD-10 Finland
Mixed personality disorders
6.0
12.4
22
38
N99
ICPC
Neurological disease other
10.0
12.3
24
25
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.1
12.3
26
53
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
12.3
70
280
C03CA01
ATC
furosemide; systemic
2.0
12.2
178
1059
N03AX18
ATC
lacosamide; systemic
16.3
12.2
19
12
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.7
12.2
23
42
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
6.2
12.2
21
35
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
12.1
72
294
X58
ICD-10 Finland
Exposure to other specified factors
2.3
12.1
109
539
N05AX08
ATC
risperidone; systemic
2.6
12.1
73
301
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.0
12.0
34
88
Z3231
NOMESCO Finland
Registered nurse
2.0
11.9
171
1010
ZY010
NOMESCO Finland
Hospital outpatient
3.3
11.8
47
153
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
11.8
92
427
J46
ICD-10 Finland
Status asthmaticus
4.9
11.8
26
55
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.1
11.7
33
85
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
8.9
11.6
24
28
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
23.5
11.6
16
7
R39.1
ICD-10 Finland
Other difficulties with micturition
4.6
11.6
28
64
78151
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Aphasia
+∞
11.5
11
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
+∞
11.5
11
*
M54.1
ICD-10 Finland
Radiculopathy
3.7
11.5
37
105
G82.2
ICD-10 Finland
Paraplegia, unspecified
122.4
11.5
12
*
F44.4
ICD-10 Finland
Dissociative motor disorders
122.4
11.5
12
*
G35
ICD-10 Finland
Multiple sclerosis
8.6
11.4
24
29
P99
ICPC
Psychological disorders other
4.1
11.4
31
78
R55
ICD-10 Finland
Syncope and collapse
2.5
11.2
77
337
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.5
11.1
27
62
Z2221
NOMESCO Finland
Medical doctor
2.0
11.1
168
1008
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
11.1
128
697
B01AB05
ATC
enoxaparin; parenteral
1.9
11.1
179
1098
PA6AD
NOMESCO Finland
CT of neck arteries
3.7
11.1
36
103
N05AX12
ATC
aripiprazole; systemic
3.5
11.0
38
113
N88
ICPC
Epilepsy
15.9
10.9
17
11
A46
ICD-10 Finland
Erysipelas
2.3
10.9
96
470
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
10.8
171
1039
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.7
10.8
25
55
N06AX21
ATC
duloxetine; oral
2.4
10.8
84
389
G40.89
ICD-10 Finland
Other epilepsy
18.3
10.8
16
9
A01
ICPC
Pain general/multiple sites
2.5
10.7
73
319
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
10.6
87
412
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.8
10.5
54
204
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
10.5
162
975
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.0
10.5
48
170
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
+∞
10.4
10
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
8.4
10.4
22
27
F41.09
ICD-10 Finland
UNS Panic Syndrome
4.2
10.3
28
70
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
19.2
10.3
15
8
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
10.3
120
655
SPAT1254
SPAT
Administration of medicine
2.2
10.2
91
446
N05CD08
ATC
midazolam; nasal, systemic
4.8
10.1
23
50
N30.0
ICD-10 Finland
Acute cystitis
2.1
10.0
105
549
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
10.0
120
660
C07AB07
ATC
bisoprolol; oral
1.8
10.0
267
1899
KH1AD
NOMESCO Finland
CT of urinary organs
4.0
10.0
28
72
A11
ICPC
Chest pain NOS
2.5
9.8
62
261
G43.9
ICD-10 Finland
Migraine, unspecified
2.8
9.7
50
189
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.9
9.6
21
44
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.9
9.6
21
44
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
9.3
9.6
19
21
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
9.6
89
444
R06.0
ICD-10 Finland
Dyspnoea
1.9
9.6
169
1059
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
9.5
85
417
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
9.4
84
412
34400
ICD-8 Finland
Other cerebral paralysis, Hemiplegia NUD
+∞
9.4
9
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
9.4
157
966
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
9.4
52
205
XKD00
NOMESCO Finland
Uroflowmetry
2.2
9.3
86
427
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.9
9.3
27
71
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
9.3
117
654
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
9.2
77
367
P29
ICPC
Psychological sympt/compl other
2.6
9.2
57
237
J01MA02
ATC
ciprofloxacin; systemic
1.8
9.2
221
1515
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.0
9.2
42
149
N03AX11
ATC
topiramate; oral
3.9
9.2
27
72
183
Kela drug reimbursment
Lamotrigin and topiramate
8.5
9.1
19
23
B01AC04
ATC
clopidogrel; oral
2.1
9.1
97
510
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
9.0
149
911
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.7
9.0
51
203
H02AB09
ATC
hydrocortisone; systemic
4.3
9.0
23
55
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
9.0
404
3295
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.1
9.0
94
491
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.4
9.0
64
285
M79.6
ICD-10 Finland
Pain in limb
1.7
8.9
254
1824
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
8.8
118
674
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.5
8.7
30
89
N05AN01
ATC
lithium; oral
4.1
8.7
24
61
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.1
8.7
24
61
L12
ICPC
Hand/finger symptom/complaint
2.0
8.7
107
593
R96
ICPC
Asthma
2.4
8.6
63
283
ZXD35
NOMESCO Finland
Usual procedure
3.9
8.6
25
66
C09AA05
ATC
ramipril; oral
1.9
8.5
141
861
A02BC02
ATC
pantoprazole; systemic
1.8
8.5
379
3056
G41.9
ICD-10 Finland
Status epilepticus, unspecified
20.4
8.5
12
6
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
3.3
8.5
32
101
Z71.8
ICD-10 Finland
Other specified counselling
1.7
8.4
202
1376
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.0
8.4
18
37
N05BA09
ATC
clobazam; oral
13.0
8.4
14
11
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
8.4
50
204
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
8.4
72
347
G83.2
ICD-10 Finland
Monoplegia of upper limb
+∞
8.4
8
*
N06AA09
ATC
amitriptyline; systemic
2.4
8.3
58
255
ZXD05
NOMESCO Finland
Urgent procedure
1.8
8.3
173
1131
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.5
8.3
29
87
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.2
8.3
33
108
N86
ICPC
Multiple sclerosis
14.7
8.2
13
9
A97
ICPC
No disease
1.9
8.2
122
719
P15
ICPC
Chronic alcohol abuse
3.7
8.2
26
73
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.3
8.2
31
98
R60.0
ICD-10 Finland
Localized oedema
2.1
8.2
79
399
S22.3
ICD-10 Finland
Fracture of rib
2.5
8.2
52
219
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.4
8.2
30
93
F32.8
ICD-10 Finland
Other depressive episodes
4.9
8.2
18
38
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
4.9
8.2
18
38
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
8.2
64
297
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
8.1
47
189
G40
ICD-10 Finland
Epilepsy
8.3
8.1
17
21
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
8.1
202
1388
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.4
8.1
20
32
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.2
8.1
21
51
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
22.4
8.0
11
5
T78.4
ICD-10 Finland
Allergy, unspecified
3.1
8.0
33
110
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
8.0
69
333
R07.3
ICD-10 Finland
Other chest pain
2.2
8.0
72
354
N30.9
ICD-10 Finland
Cystitis, unspecified
2.6
8.0
47
191
XF600
NOMESCO Finland
Bloodpressure measurement
2.7
8.0
44
173
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
4.0
8.0
22
56
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
7.9
66
314
U08
ICPC
Urinary retention
6.2
7.9
20
33
AA5PD
NOMESCO Finland
CT examination of brain pefusion
13.3
7.9
13
10
F34.1
ICD-10 Finland
Dysthymia
3.1
7.9
33
111
C08CA01
ATC
amlodipine; oral
1.7
7.9
203
1405
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
7.9
108
620
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.2
7.9
67
322
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.9
7.8
37
134
N17
ICPC
Vertigo/dizziness
2.1
7.8
80
414
R03BB04
ATC
tiotropium bromide; inhalant
2.3
7.7
60
277
SPAT1216
SPAT
Assessment of functional ability
2.0
7.7
88
473
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
7.7
69
338
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.8
7.7
23
62
F05.9
ICD-10 Finland
Delirium, unspecified
4.6
7.7
18
40
R5110, ,
SPAT
2.3
7.7
57
258
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
7.7
57
258
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
7.7
71
353
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
7.6
41
159
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
7.6
183
1241
H02AB06
ATC
prednisolone; systemic
1.6
7.6
265
1979
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
7.6
57
259
N02BE01
ATC
paracetamol; systemic, rectal
2.1
7.6
495
4391
N02BF02
ATC
pregabalin; oral
2.6
7.5
44
178
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
7.3
7.5
17
24
ZXA00
NOMESCO Finland
Right side
1.8
7.5
144
918
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
81.1
7.4
8
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
81.1
7.4
8
*
34099
ICD-8 Finland
Multiple sclerosis
81.1
7.4
8
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
7.4
65
316
R52.0
ICD-10 Finland
Acute pain
3.2
7.4
29
94
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.9
7.4
35
127
RS220, ,
NOMESCO Finland
8.5
7.4
15
18
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.7
7.4
41
162
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
9.5
7.3
14
15
K84
ICPC
Heart disease other
3.9
7.3
21
55
G83.3
ICD-10 Finland
Monoplegia, unspecified
+∞
7.3
7
*
S21
ICPC
Skin texture symptom/complaint
2.0
7.3
89
490
ZXE00
NOMESCO Finland
One hour or less
1.7
7.3
212
1509
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.4
7.3
18
42
Z43.5
ICD-10 Finland
Attention to cystostomy
16.0
7.3
11
7
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.8
7.2
36
134
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
7.5
7.2
16
22
F10.09
ICD-10 Finland
Alcohol intoxication UNS
4.0
7.2
20
51
WX402
NOMESCO Finland
General anaesthesia
1.8
7.2
125
771
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.5
7.2
24
70
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
30.4
7.2
9
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
7.2
46
195
Z72.8
ICD-10 Finland
Other problems related to lifestyle
20.3
7.2
10
5
7803A
ICD-9 Finland
General symptoms, Convulsions
8.1
7.1
15
19
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.2
7.1
19
47
L03
ICPC
Low back symptom/complaint
1.7
7.1
166
1115
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
4.3
7.1
18
43
R2110
NOMESCO Finland
Giving the first information
2.6
7.0
42
172
K59.0
ICD-10 Finland
Constipation
2.6
7.0
40
160
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
7.0
53
242
S29
ICPC
Skin symptom/complaint other
1.8
7.0
116
705
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
7.0
61
296
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.2
7.0
27
87
M54.5
ICD-10 Finland
Low back pain
1.6
6.9
209
1496
R51.81
ICD-10 Finland
Facial pain NOS
4.1
6.9
19
48
X57
ICD-10 Finland
Unspecified privation
4.1
6.9
19
48
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
3.4
6.9
25
77
S63.6
ICD-10 Finland
Sprain and strain of finger(s)
3.0
6.8
30
104
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
6.8
115
702
J01EA01
ATC
trimethoprim; systemic
1.7
6.8
139
897
M79.1
ICD-10 Finland
Myalgia
1.9
6.8
96
555
3001A
ICD-9 Finland
Neurotic disorders, Hysteria[KONVERSIOHÄIRIÖ]
40.6
6.8
8
*
S18
ICPC
Laceration/cut
1.6
6.8
252
1897
G40.10
ICD-10 Finland
Simple partial seizures
16.9
6.8
10
6
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.6
6.8
39
157
XCK00
NOMESCO Finland
Perimetry
2.6
6.8
39
157
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.0
6.7
30
105
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
6.7
48
214
XA402
NOMESCO Finland
ENMG
3.8
6.7
20
54
A99
ICPC
Disease/condition unspecnature/site
2.1
6.7
64
322
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.1
6.7
18
45
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
5.6
6.7
18
33
WX882
NOMESCO Finland
High dependency care
3.7
6.6
21
59
204
Kela drug reimbursment
Leukemia lymphatica
3.3
6.6
24
74
SPAT1167
SPAT
Insertion of urinary catheter
3.5
6.6
22
64
XKC03
NOMESCO Finland
Water cystometry
3.5
6.6
22
64
F60.7
ICD-10 Finland
Dependent personality disorder
12.4
6.6
11
9
R31
ICD-10 Finland
Unspecified haematuria
2.2
6.6
59
289
OAB43, ,
SPAT
0.5
6.6
84
1391
UJF32
NOMESCO Finland
Coloscopy
1.7
6.6
139
905
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.9
6.6
19
50
U04
ICPC
Incontinence urine
2.6
6.6
38
153
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
6.6
102
607
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.0
6.6
71
374
WX730
NOMESCO Finland
Conventional respirator
7.0
6.6
15
22
T90.5
ICD-10 Finland
Sequelae of intracranial injury
7.0
6.6
15
22
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
6.5
83
463
WW200
NOMESCO Finland
Immunization
3.7
6.5
20
55
B01AA03
ATC
warfarin; systemic
1.9
6.5
96
562
EBA00
NOMESCO Finland
Extraction of tooth
1.6
6.5
198
1417
J01MA12
ATC
levofloxacin; systemic
1.8
6.5
102
610
R50.9
ICD-10 Finland
Fever, unspecified
1.9
6.5
91
525
N05BA04
ATC
oxazepam; oral
1.7
6.4
152
1019
SPAT1285
SPAT
Provision of consultation response
2.7
6.4
33
125
R13
ICD-10 Finland
Dysphagia
2.4
6.4
45
199
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.8
6.4
31
114
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
6.4
50
232
N29
ICPC
Neurological sympt/complt other
5.3
6.4
18
35
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.7
6.4
20
56
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.3
6.3
23
71
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.5
6.3
21
61
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.4
6.3
45
200
ZX120
NOMESCO Finland
Intravenous
2.2
6.3
57
280
A08
ICPC
Swelling
2.5
6.3
38
156
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.1
6.3
26
87
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
6.3
134
874
H03AA01
ATC
levothyroxine sodium; systemic
1.7
6.3
125
800
S62.6
ICD-10 Finland
Fracture of other finger
2.7
6.3
32
121
34308
ICD-8 Finland
Cerebral spastic infantile paralysis, Alia definita
+∞
6.3
6
*
34300
ICD-8 Finland
Cerebral spastic infantile paralysis, Hemiplegia spastica
+∞
6.3
6
*
G81.1
ICD-10 Finland
Spastic hemiplegia
+∞
6.3
6
*
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
+∞
6.3
6
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
6.3
6
*
G83.1
ICD-10 Finland
Monoplegia of lower limb
+∞
6.3
6
*
SPAT1243
SPAT
Psychiatric/psychological examination
3.7
6.2
19
52
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
6.2
117
737
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.5
6.2
39
164
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.2
240
1814
M89.0
ICD-10 Finland
Algoneurodystrophy
7.8
6.2
13
17
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.8
6.1
18
48
RS121, ,
NOMESCO Finland
12.7
6.1
10
8
R1250, ,
SPAT
3.2
6.1
23
73
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
8.7
6.1
12
14
A02BC03
ATC
lansoprazole; oral
1.6
6.1
154
1050
R51
ICD-10 Finland
Headache
2.5
6.1
36
147
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
3.5
6.1
20
58
S80.0
ICD-10 Finland
Contusion of knee
2.2
6.1
51
244
K91
ICPC
Cerebrovascular disease
6.1
6.0
15
25
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.0
6.0
68
364
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
316
1459
3.69
50.79
4.3
2.0
240.75
214.36
u/l
0.17
308
1393
126
436
3.44
29.66
3.8
2.5
28.94
45.09
u/l
0.86
107
360
351
2119
2.77
29.43
10.5
6.4
1.21
1.21
mmol/l
0.38
338
1963
174
737
2.98
29.01
4.9
3.1
1.87
2.19
e6/l
0.26
89
351
58
115
5.51
28.42
1.4
1.2
473.12
447.65
mg/l
0.25
52
110
54
101
5.81
28.16
1.3
1.2
3.60
3.71
mmol/l
0.35
47
94
373
2357
2.76
27.98
10.4
7.1
1.21
1.21
mmol/l
0.08
347
2041
277
1538
2.59
26.71
6.0
3.4
40.82
86.39
e6/l
0.49
216
1176
338
2081
2.59
25.95
6.4
5.0
35.64
36.06
g/l
0.71
322
1972
52
103
5.47
25.46
1.3
1.2
4.75
12.96
e6/l
0.58
28
79
173
783
2.75
24.98
4.4
3.4
0.82
0.82
mmol/l
0.05
167
751
52
105
5.36
24.93
1.3
1.3
274.31
188.15
e6/l
0.20
32
84
172
783
2.73
24.49
4.9
2.9
0.56
1.09
e6/l
2.68
86
400
187
905
2.61
23.39
5.4
3.6
140.08
360.43
ng/l
1.88
138
688
239
1305
2.46
23.01
5.9
3.2
0.43
0.36
e6/l
0.26
182
950
131
538
2.88
22.51
7.0
8.0
0.47
0.87
mmol/l
0.44
114
455
27
30
9.41
22.24
1.1
1.0
—
—
—
0
0
333
2149
2.37
21.41
16.2
13.4
1.23
1.23
inr
0.00
280
1776
130
545
2.81
21.40
3.6
3.0
7.75
7.42
umol/l
0.06
114
486
398
2780
2.51
21.34
9.6
5.0
6.52
6.67
mmol/l
0.90
389
2630
32
49
6.87
20.23
1.1
1.0
—
—
—
0
0
419
3038
2.53
20.02
8.2
4.5
4531.25
722.02
e6/l
—
8
54
31
47
6.93
19.77
1.1
1.0
—
—
—
0
0
31
48
6.78
19.39
1.1
1.0
—
—
—
0
0
275
1689
2.24
19.19
5.1
3.4
31.04
31.53
u/l
0.10
261
1607
132
587
2.64
19.17
2.5
1.8
—
—
—
0
0
161
788
2.47
19.11
2.6
1.9
—
—
—
0
0
194
1050
2.30
18.19
4.4
2.7
6.35
6.00
e6/l
0.11
186
963
125
555
2.61
18.13
2.6
1.8
—
—
—
0
0
267
1655
2.18
17.82
4.2
3.3
2.35
2.35
mmol/l
0.23
248
1518
357
2519
2.16
16.59
9.2
6.5
10.41
11.48
umol/l
1.28
348
2404
99
409
2.73
16.47
6.3
6.8
9.24
9.35
mmol/l
0.04
93
391
78
296
2.90
15.17
6.4
10.3
23.84
24.32
mmol/l
0.54
78
290
81
321
2.78
14.52
2.6
2.4
28.99
20.22
au/ml
—
9
30
72
272
2.89
14.09
2.1
1.7
—
—
—
0
0
188
1095
2.08
14.00
2.8
1.8
1.01
1.22
mg/l
0.53
160
843
103
472
2.45
13.71
7.4
3.8
1.67
1.76
mmol/l
0.09
91
397
106
495
2.41
13.53
7.3
3.8
5.98
5.76
kpa
1.31
100
480
374
2795
2.03
13.51
16.2
9.7
4.08
4.12
e9/l
0.13
332
2451
205
1246
2.02
13.49
2.4
2.2
2.66
2.94
mg/l
1.19
174
1085
42
121
3.67
12.76
4.8
3.1
1.77
2.28
index
0.26
31
71
35
89
4.13
12.64
1.5
1.3
—
—
—
0
0
35
89
4.13
12.64
1.5
1.3
—
—
—
0
0
89
396
2.48
12.57
3.5
2.7
10.37
10.45
g/l
0.06
82
364
22
39
5.83
12.03
1.4
1.1
—
—
—
0
0
146
822
2.05
11.61
2.5
2.4
13.73
13.29
umol/l
0.27
138
768
44
142
3.28
11.25
3.7
2.9
196.95
180.82
%
0.49
44
137
80
359
2.43
11.05
2.0
1.6
—
—
—
0
0
287
2053
1.82
10.82
2.6
2.1
88.37
96.57
pmol/l
2.36
190
1120
297
2153
1.81
10.66
3.1
2.6
71.44
76.31
nmol/l
1.78
273
1963
340
2573
1.83
10.52
5.4
3.8
22.33
3.02
estimate
0.40
60
537
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
39
123
3.33
10.34
9.3
2.7
0.24
0.34
iu/ml
1.44
19
66
20
38
5.42
10.18
1.8
2.0
—
—
—
0
0
208
1369
1.83
10.15
2.0
1.7
18.58
20.32
nmol/l
0.99
185
1160
19
19
10.31
10.08
1.1
1.0
—
—
—
0
0
157
953
1.90
9.85
3.3
2.8
2.46
2.45
mmol/l
0.63
143
865
125
703
2.00
9.81
2.6
2.5
25.36
22.63
%
1.09
117
659
31
87
3.71
9.79
1.2
1.1
—
—
—
0
0
224
1521
1.79
9.77
4.2
2.6
56.46
64.38
u/l
0.74
218
1425
438
3628
1.97
9.76
13.6
8.2
87.71
77.99
u/l
2.24
429
3452
87
427
2.23
9.74
7.2
3.3
4.91
4.60
kpa
0.70
82
414
133
767
1.96
9.70
2.5
2.4
2.35
2.34
g/l
0.07
128
706
179
1139
1.84
9.66
5.6
3.9
1.02
1.02
kg/l
0.01
137
754
334
2551
1.77
9.64
5.3
3.8
0.00
0.00
estimate
0.50
58
523
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
18
18
10.29
9.58
1.1
1.1
—
—
—
0
0
57
235
2.59
9.38
1.7
1.4
—
—
—
0
0
41
143
3.02
9.22
1.2
1.3
—
—
—
0
0
178
1146
1.81
9.16
3.4
2.2
—
—
—
0
0
75
361
2.25
8.78
3.7
3.9
80.38
85.33
ng/l
0.24
67
321
75
361
2.25
8.78
2.3
2.3
6.68
7.39
ug/l
0.18
64
326
335
2602
1.72
8.72
5.6
3.9
0.00
0.62
estimate
0.51
56
499
19
26
7.53
8.51
1.0
1.0
1.15
1.09
u/l
—
8
13
63
286
2.36
8.44
4.1
3.7
1.68
1.91
mmol/l
0.20
46
210
18
23
8.05
8.42
3.1
2.0
235.36
61.31
umol/l
0.99
11
13
253
1834
1.70
8.40
6.2
3.7
254.47
37.04
ng/l
0.46
182
1233
203
1389
1.73
8.32
3.8
3.2
1277.58
1331.10
ng/l
0.08
181
1181
20
31
6.65
8.25
1.2
1.2
0.51
0.53
ratio
0.36
11
19
95
517
2.01
8.07
5.3
4.5
261.01
237.15
u/l
0.51
90
491
288
2202
1.64
7.50
3.5
2.7
—
—
estimate
—
0
0
419
3549
1.73
7.11
5.6
4.3
14.17
11.09
mm/h
3.40
402
3324
44
187
2.47
6.82
1.5
1.6
390.75
284.62
mu/l
0.78
39
173
40
163
2.57
6.76
1.4
1.3
—
—
—
0
0
83
460
1.95
6.66
2.5
2.4
0.21
0.22
g/l
0.37
83
433
25
83
3.11
6.15
1.3
1.3
2.00
4.29
u/ml
—
6
31
296
2347
1.56
6.14
3.6
3.0
116.91
122.17
ug/l
0.17
281
2213
25
85
3.03
5.91
1.4
1.3
4.07
4.21
u/ml
0.03
14
39
17
47
3.70
5.52
2.2
1.8
89.22
89.25
%
0.01
17
47
34
143
2.47
5.41
1.4
1.4
251.05
303.63
ug/g
0.70
19
84
119
780
1.67
5.41
1.9
1.7
976.49
1181.47
nmol/l
2.01
101
613
105
672
1.69
5.21
3.5
1.9
1.66
1.47
%
1.18
97
596
417
3642
1.58
5.09
5.6
4.4
14.60
14.73
pmol/l
0.45
389
3374
10
12
8.46
5.08
2.0
2.0
19.86
14.84
umol/l
—
10
12
167
1210
1.54
4.96
3.4
2.7
337.90
343.71
umol/l
0.30
153
1095
81
489
1.77
4.94
2.5
2.0
373.08
382.38
nmol/l
0.10
76
459
11
17
6.58
4.79
1.1
1.1
—
—
—
0
0
33
146
2.34
4.73
1.3
1.4
—
—
—
0
0
41
199
2.14
4.73
1.8
2.3
1.19
1.47
g/l
1.23
34
183
384
3323
1.50
4.63
5.2
3.3
61.33
44.81
u/l
2.00
370
3165
56
308
1.91
4.60
2.1
3.8
4.56
4.61
pmol/l
0.08
47
271
29
124
2.41
4.49
1.6
1.5
—
—
—
0
0
10
15
6.77
4.48
1.1
1.1
—
—
—
0
0
12
23
5.31
4.48
2.3
4.8
102.17
96.78
%
0.22
12
23
13
28
4.73
4.39
1.2
1.1
—
—
—
0
0
50
269
1.94
4.39
9.6
2.7
0.55
0.64
%
1.52
50
269
69
413
1.77
4.34
3.8
2.7
0.34
0.42
e6/l
0.13
69
392
37
179
2.14
4.32
4.9
4.4
25.17
25.05
mmol/l
0.09
32
170
46
243
1.97
4.25
2.3
1.5
0.35
0.27
mg/l
0.45
21
107
27
117
2.37
4.08
8.9
3.9
1.54
3.21
ratio
1.14
16
70
27
120
2.31
3.87
1.3
1.5
18273.60
14620.89
e6/l
0.14
15
85
17
61
2.84
3.72
1.1
1.3
415.00
363.73
pmol/l
0.15
12
56
13
34
3.89
3.71
1.2
1.2
—
—
—
0
0
8
12
6.74
3.68
2.8
1.5
0.64
0.62
mmol/l
—
8
12
502
4686
1.72
3.64
33.7
15.4
21.01
23.08
mg/l
0.99
469
3851
28
130
2.21
3.64
9.1
4.0
43.38
102.85
mg/l
0.70
28
113
28
130
2.21
3.64
9.0
4.0
39.60
30.58
mg/l
0.38
28
113
11
25
4.47
3.64
1.5
1.6
—
—
—
0
0
358
3126
1.41
3.60
3.3
3.2
—
—
—
0
0
10
22
4.61
3.44
4.0
2.7
621.50
677.82
u/ml
—
10
22
15
53
2.88
3.38
1.3
11.5
5.67
6.95
mmol/l
—
10
44
26
121
2.21
3.37
1.9
1.7
—
—
—
0
0
469
4332
1.52
3.26
7.2
5.3
1.90
1.87
mu/l
0.15
446
4039
14
49
2.91
3.21
1.2
1.2
—
—
—
0
0
238
1968
1.37
3.21
5.2
3.7
0.00
0.03
estimate
1.64
44
438
13
44
3.00
3.15
1.2
1.2
—
—
—
0
0
6
8
7.57
3.06
1.3
1.0
—
—
—
0
0
6
8
7.57
3.06
1.2
1.3
—
—
—
0
0
13
45
2.93
3.04
1.2
1.2
—
—
—
0
0
20
87
2.35
3.04
1.4
1.7
3.87
5.08
mmol/24h
0.94
20
73
16
63
2.59
2.98
1.3
1.4
—
—
—
0
0
16
63
2.59
2.98
1.3
1.4
—
—
—
0
0
13
46
2.87
2.93
1.2
1.2
—
—
—
0
0
13
46
2.87
2.93
1.2
1.2
—
—
—
0
0
32
562
0.54
2.91
2.1
2.0
3.78
3.52
ratio
0.36
26
454
16
64
2.54
2.89
1.3
1.4
—
—
—
0
0
6
9
6.72
2.87
1.3
1.3
—
—
—
0
0
37
209
1.83
2.86
2.8
2.3
35.81
40.10
u/l
0.68
32
192
478
4466
1.50
2.80
29.8
14.6
85.60
83.22
ml/min/173m2
1.43
448
4128
25
125
2.05
2.75
3.5
2.4
12.61
12.70
mg/l
0.03
25
118
16
67
2.43
2.65
1.3
1.4
—
—
—
0
0
10
30
3.37
2.61
1.8
2.5
—
—
—
0
0
28
149
1.93
2.61
1.5
1.4
11.96
9.03
u/l
0.41
21
120
22
418
0.51
2.59
1.6
1.8
3.13
3.51
mmol/l
0.58
16
313
14
56
2.54
2.55
1.2
1.3
—
—
—
0
0
20
95
2.15
2.51
1.1
1.5
164.14
164.84
au/ml
—
7
29
25
130
1.97
2.49
1.7
1.6
—
—
—
0
0
7
16
4.42
2.48
1.3
1.3
—
—
—
0
0
172
1405
1.32
2.37
5.5
3.9
0.00
0.01
estimate
0.99
52
497
146
1165
1.34
2.36
1.4
1.3
0.74
1.28
u/ml
1.43
25
320
16
71
2.29
2.36
1.4
1.3
0.46
26.32
nmol/l
0.50
16
66
21
105
2.04
2.34
1.7
1.4
—
—
—
0
0
16
72
2.26
2.29
1.4
1.5
—
—
—
0
0
15
66
2.31
2.26
1.3
1.4
—
—
—
0
0
7
18
3.92
2.26
1.4
1.6
—
—
—
0
0
13
54
2.44
2.21
1.3
1.3
—
—
—
0
0
12
48
2.53
2.20
1.0
1.1
—
65.00
—
0
6
15
67
2.27
2.19
1.3
1.4
—
—
—
0
0
18
87
2.10
2.19
1.8
1.5
—
—
—
0
0
190
1589
1.30
2.18
5.5
3.6
7.69
7.81
mmol/l
0.13
176
1351
16
74
2.20
2.16
1.3
1.1
—
—
—
0
0
7
19
3.72
2.15
1.4
1.6
—
—
—
0
0
10
36
2.81
2.14
2.2
1.6
—
—
—
0
0
8
25
3.23
2.10
1.0
1.3
—
—
—
0
0
8
25
3.23
2.10
1.0
1.3
—
—
—
0
0
14
62
2.29
2.09
1.4
1.4
—
—
—
0
0
13
56
2.35
2.06
1.2
1.2
—
—
—
0
0
52
357
1.50
1.97
1.2
1.3
201.34
151.74
u/ml
0.26
19
145
17
85
2.03
1.92
1.6
1.4
—
—
—
0
0
470
4451
1.36
1.87
5.9
4.9
5.97
5.93
mmol/l
0.33
442
4139
14
66
2.15
1.83
1.9
1.5
—
—
—
0
0
7
23
3.07
1.80
1.4
1.5
—
—
—
0
0
7
23
3.07
1.80
1.9
2.5
—
—
—
0
0
7
23
3.07
1.80
1.9
2.5
—
—
—
0
0
8
29
2.78
1.79
1.6
3.3
60.13
138.93
nmol/l
—
8
29
20
109
1.87
1.79
2.9
2.1
128.47
127.73
g/l
0.04
15
86
24
139
1.76
1.78
1.7
2.1
3.01
4.46
iu/l
—
10
53
16
81
2.00
1.76
1.4
1.7
—
—
—
0
0
7
24
2.94
1.72
1.1
1.7
—
—
—
0
0
7
24
2.94
1.72
1.1
1.7
—
—
—
0
0
7
24
2.94
1.72
1.1
1.7
—
—
—
0
0
7
24
2.94
1.72
1.1
1.7
—
—
—
0
0
17
89
1.94
1.71
2.1
3.4
—
837.44
—
0
9
10
41
2.46
1.65
1.2
1.6
—
—
—
0
0
119
969
1.29
1.64
1.6
1.8
84536518.49
26955904.54
pmol/l
0.30
97
831
11
49
2.27
1.64
1.6
1.3
46.09
50.86
u/l
0.25
11
43
10
42
2.41
1.62
1.1
1.6
—
—
—
0
0
10
42
2.41
1.62
1.1
1.6
—
—
—
0
0
10
42
2.41
1.62
1.1
1.6
—
—
—
0
0
12
56
2.17
1.62
1.2
1.8
—
—
—
0
0
29
183
1.62
1.60
4.2
2.1
6841.89
5863.41
u/l
—
9
72
8
32
2.52
1.60
1.5
1.1
—
—
—
0
0
10
43
2.35
1.59
1.1
1.0
—
—
—
0
0
6
20
3.02
1.58
1.0
1.3
—
—
—
0
0
6
20
3.02
1.58
1.0
1.3
—
—
—
0
0
42
290
1.48
1.58
1.4
1.4
25.62
23.63
iu/l
0.16
35
250
26
161
1.65
1.55
2.7
1.8
—
—
—
0
0
61
454
1.39
1.55
5.6
3.3
—
—
—
0
0
8
33
2.44
1.54
1.5
1.4
—
—
—
0
0
50
360
1.43
1.53
3.9
2.8
61.94
69.10
ml/min/173m2
0.74
17
156
5
15
3.35
1.52
1.0
1.1
—
—
—
0
0
16
87
1.86
1.47
1.2
1.1
1.40
113.88
iu/ml
—
5
19
7
155
0.44
1.44
1.7
1.5
—
—
—
0
0
5
16
3.14
1.44
1.0
1.1
—
—
—
0
0
18
103
1.77
1.42
1.6
1.4
—
—
—
0
0
27
174
1.58
1.40
3.0
2.0
—
—
—
0
0
5
17
2.96
1.36
5.6
4.4
9.56
10.51
kpa
—
5
17
5
17
2.96
1.36
5.6
4.4
5.50
4.72
kpa
—
5
17
102
839
1.26
1.31
1.5
1.3
32.91
13.30
u/ml
0.27
28
338
170
1480
1.21
1.29
4.2
4.2
6.74
9.95
mg/mmol
0.75
120
954
5
18
2.79
1.28
1.0
3.1
211.60
205.83
u/l
—
5
18
12
62
1.96
1.28
1.4
1.4
—
—
—
0
0
10
48
2.10
1.28
1.2
1.9
—
—
—
0
0
510
4948
1.36
1.24
39.9
19.5
76.97
77.05
umol/l
0.01
505
4892
5
19
2.65
1.22
1.2
1.0
—
—
—
0
0
8
37
2.18
1.22
1.0
1.1
—
—
—
0
0
110
928
1.23
1.14
1.6
1.3
29.11
31.81
iu/ml
0.09
38
287
17
103
1.67
1.14
1.6
1.3
337.40
243.99
u/ml
—
10
53
33
235
1.43
1.11
1.3
1.3
—
—
—
0
0
7
31
2.27
1.10
1.4
1.5
8.57
8.50
u/l
—
7
26
5
21
2.39
1.09
2.6
1.9
29.60
83.36
ug/l
—
5
21
60
473
1.30
1.09
2.5
4.6
9.23
34.18
ug/l
0.80
45
390
27
186
1.47
1.08
2.4
3.5
530.60
1342.61
u/ml
0.48
20
161
458
4402
1.23
1.07
6.9
6.2
39.46
39.17
mmol/mol
0.26
440
4172
48
372
1.32
0.99
1.3
1.4
—
—
—
0
0
21
140
1.52
0.99
1.2
1.2
—
—
—
0
0
21
141
1.51
0.96
1.2
1.1
—
—
—
0
0
18
117
1.56
0.94
1.4
1.8
—
—
—
0
0
6
120
0.49
0.94
1.5
1.6
56.95
59.47
ug/l
—
6
102
163
1453
1.17
0.94
4.7
3.2
0.00
0.07
estimate
0.60
44
426
6
114
0.52
0.83
1.3
1.5
—
—
—
0
0
6
33
1.83
0.79
1.0
1.3
—
—
—
0
0
24
174
1.40
0.78
1.3
1.7
—
—
—
0
0
10
59
1.71
0.76
1.9
3.3
3.75
69.33
u/ml
—
10
59
18
125
1.45
0.73
1.1
1.3
—
—
—
0
0
5
25
2.01
0.73
2.2
1.3
58.60
80.88
ng/l
—
5
25
41
328
1.27
0.71
2.3
2.0
—
—
—
0
0
7
42
1.67
0.68
3.9
3.3
642.00
1132.81
mg
—
7
42
15
213
0.70
0.66
1.5
1.6
1038.03
950.56
mu/l
0.14
15
181
46
552
0.82
0.62
5.5
4.7
32.03
31.53
%
0.10
35
379
8
49
1.64
0.62
3.8
4.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
45.12
—
0
22
14
98
1.44
0.57
2.3
1.5
—
—
—
0
0
502
4928
1.19
0.57
19.9
11.7
27.05
26.72
u/l
0.18
495
4815
10
67
1.50
0.50
1.1
1.2
—
—
—
0
0
23
181
1.28
0.49
1.7
2.0
31.48
37.39
nmol/l
0.81
23
173
459
4684
0.89
0.48
6.5
5.6
2.65
2.75
mmol/l
1.60
443
4398
7
48
1.46
0.47
2.6
2.8
2.40
117.16
nmol/l
—
7
48
10
141
0.70
0.45
1.4
1.4
—
—
—
0
0
451
4600
0.90
0.43
5.6
4.9
1.37
1.45
mmol/l
4.08
434
4323
33
276
1.21
0.43
2.2
1.9
—
—
—
0
0
11
78
1.42
0.43
1.6
1.7
—
—
—
0
0
8
57
1.41
0.42
1.0
1.1
—
—
—
0
0
27
222
1.23
0.42
1.4
2.2
11.53
7.62
iu/ml
—
6
51
0
16
0.00
0.41
0.0
1.3
—
0.59
—
0
11
5
36
1.39
0.38
1.8
1.5
61.80
74.75
umol/l
—
5
36
19
152
1.26
0.37
2.1
2.9
—
—
—
0
0
9
69
1.31
0.37
1.1
1.4
—
—
—
0
0
189
1987
0.93
0.36
2.1
1.9
1.56
1.39
mmol/l
1.54
168
1704
19
154
1.24
0.34
1.3
1.3
—
—
—
0
0
6
45
1.34
0.34
1.0
1.5
—
—
—
0
0
20
165
1.22
0.31
1.4
1.6
0.03
0.10
iu/ml
—
5
33
139
1462
0.93
0.27
4.6
4.9
2.19
2.43
ug/l
0.13
128
1324
56
511
1.11
0.26
8.7
6.5
—
—
—
0
0
456
4619
0.93
0.25
5.7
5.0
4.51
4.66
mmol/l
2.23
441
4364
6
84
0.71
0.24
1.3
1.3
—
103.33
—
0
6
5
40
1.25
0.22
3.2
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
70
747
0.93
0.21
1.4
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
7
61
1.15
0.17
1.0
1.0
—
—
—
0
0
18
157
1.15
0.17
1.4
1.2
—
24.97
—
0
7
81
852
0.94
0.17
2.8
2.9
0.90
0.80
ug/l
0.18
62
506
13
151
0.86
0.16
1.3
1.5
—
—
—
0
0
9
78
1.16
0.15
1.0
1.1
—
1.49
—
0
17
7
87
0.80
0.14
1.3
1.8
—
—
—
0
0
110
1141
0.96
0.14
3.7
4.3
24.06
21.91
%
0.40
43
502
14
122
1.15
0.14
1.2
1.3
—
1.13
—
0
9
9
106
0.85
0.13
1.3
1.7
—
—
—
0
0
64
612
1.05
0.11
2.2
2.1
—
—
—
0
0
10
86
1.17
0.11
6.8
3.0
11.11
9.74
pmol/l
—
10
86
10
86
1.17
0.11
1.1
1.5
0.27
0.35
nmol/l
—
5
68
99
959
1.04
0.11
1.7
1.6
—
—
—
0
0
5
45
1.11
0.10
2.4
1.7
—
—
—
0
0
8
75
1.07
0.07
1.4
1.6
62.06
50.28
ug/l
—
8
75
24
255
0.94
0.07
3.0
2.7
93.42
44.39
u/ml
0.48
24
244
27
256
1.06
0.06
1.0
1.0
—
—
—
0
0
57
557
1.03
0.04
2.2
2.0
—
—
—
0
0
509
5096
0.99
0.00
46.8
23.2
4.42
4.53
e12/l
5.15
499
5011
440
4394
1.01
0.00
4.8
4.2
1.42
1.29
mmol/l
2.81
420
4101
10
102
0.98
0.00
1.2
1.2
—
—
—
0
0
509
5093
0.99
0.00
46.7
23.3
254.59
250.89
e9/l
0.55
501
5020
21
212
0.99
0.00
1.9
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
58
0.86
-0.00
2.0
2.8
1.18
1.19
mmol/l
—
5
58
5
59
0.85
-0.00
2.0
2.8
105.60
105.71
mmol/l
—
5
59
0
5
0.00
-0.00
0.0
3.6
—
55.58
—
0
5
0
6
0.00
-0.00
0.0
8.2
—
10.50
—
0
6
0
8
0.00
-0.00
0.0
6.6
—
5.84
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
55
0.91
-0.00
1.6
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_PARALOTHUNS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_PARALOTHUNS | 2.863 [2.26, 3.63] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 320 out of 1060 females with G6_PARALOTHUNS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_PARALOTHUNS | 2.83 [2.28, 3.52] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 413 out of 1080 males with G6_PARALOTHUNS died.
Mortality risk
Mortality risk for people of age
years, who have G6_PARALOTHUNS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.199% | 0.461% |
| 5 | 1.319% | 3.017% |
| 10 | 3.301% | 7.971% |
| 15 | 6.249% | 14.537% |
| 20 | 10.48% | 24.181% |
Relationships between endpoints
↥Index endpoint: G6_PARALOTHUNS – Other and unspecified paralytic syndromes
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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