Slow fetal growth and fetal malnutrition

P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P05
  • Cause of death: ICD-10 P05

2 out of 7 registries used, show all original rules.

235

4. Check minimum number of events

None

235

5. Include endpoints

None

235

6. Filter based on genotype QC (FinnGen only)

203

Control definitions (FinnGen only)

Control exclude
P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[5-8]
Name in latin
Crescentia tarda et malnutritio fetalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12946 6759 6182
Only index persons 6781 3568 3213
Unadjusted period prevalence (%)
Whole population 0.18 0.19 0.17
Only index persons 0.13 0.13 0.12
Median age at first event (years)
Whole population 0.01 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 203 127 76
Unadjusted period prevalence (%) 0.04 0.05 0.03
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
221
Matched controls
2191
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
53.8
163.4
103
35
P05.1
ICD-10 Finland
Small for gestational age
+∞
156.0
131
*
P07.3
ICD-10 Finland
Other preterm infants
+∞
103.2
91
*
P05.0
ICD-10 Finland
Light for gestational age
+∞
94.5
84
*
602
Kela drug reimbursment
Children's severe malnutrition
10.8
41.8
51
59
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
+∞
40.8
38
*
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
+∞
38.6
36
*
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
14.0
35.5
35
29
E34.31
ICD-10 Finland
Short stature, prenatal disorder
31.4
26.6
35
13
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
6.8
21.4
37
63
WX722
NOMESCO Finland
PEEP
9.3
20.4
26
31
P07.2
ICD-10 Finland
Extreme immaturity
+∞
17.9
17
*
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
21.3
17.2
25
13
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
54.2
17.2
20
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
+∞
16.8
16
*
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
7.3
15.5
24
36
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
12.0
14.9
27
25
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
56.7
14.0
16
*
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
+∞
13.6
13
*
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
+∞
13.6
13
*
P05.9
ICD-10 Finland
Slow fetal growth, unspecified
+∞
13.6
13
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
13.0
47
147
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
12.2
38
107
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.0
12.2
72
305
A11JC
ATC
Vitamins, other combinations
49.1
12.0
14
*
P07.1
ICD-10 Finland
Other low birth weight
+∞
11.5
11
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
11.5
11
*
R4110
NOMESCO Finland
Physiotherapy
2.6
9.8
81
402
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
57.1
9.7
11
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.1
9.3
44
162
H01AC01
ATC
somatropin; parenteral
4.2
9.1
26
68
R62.0
ICD-10 Finland
Delayed milestone
3.5
8.7
33
106
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
8.5
61
280
Z38.3
ICD-10 Finland
Twin, born in hospital
92.7
8.4
9
*
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
+∞
8.4
8
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
8.2
77
401
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
8.1
93
526
WX730
NOMESCO Finland
Conventional respirator
15.6
7.8
12
8
RK312, ,
NOMESCO Finland
19.0
7.6
11
6
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
12.4
7.6
13
11
Z3226
NOMESCO Finland
Physiotherapist
2.3
7.6
73
381
F82
ICD-10 Finland
Specific developmental disorder of motor function
4.1
7.3
21
55
Z3231
NOMESCO Finland
Registered nurse
2.1
7.0
103
635
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
8.2
6.7
14
18
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
6.7
60
303
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
6.5
79
451
301
Kela drug reimbursment
Growth hormone
6.9
6.4
15
23
Z2446
NOMESCO Finland
Social worker
2.4
6.4
54
265
ZXD05
NOMESCO Finland
Urgent procedure
2.3
6.3
55
273
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
+∞
6.3
6
*
WX882
NOMESCO Finland
High dependency care
2.6
6.1
40
174

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
54
3.30
4.52
5.2
6.2
2.38
2.38
ug/l
0.00
17
54
38
193
2.15
4.05
3.0
2.7
4.48
5.50
u/l
0.64
23
109
46
257
1.98
3.80
1.8
1.5
98.64
358.41
u/ml
1.99
39
244
44
269
1.78
2.73
1.5
1.4
19.92
19.97
nmol/l
0.01
39
237
32
186
1.83
2.34
3.3
2.6
8.51
6.28
iu/l
0.34
22
117
6
15
4.04
2.03
7.5
5.9
1.59
1.55
mmol/l
—
6
15
20
105
1.98
1.98
1.7
1.8
27.40
20.23
ng/l
0.35
20
105
15
71
2.17
1.93
1.3
1.2
—
—
—
0
0
31
469
0.60
1.90
2.6
3.5
65.85
94.34
ug/g
0.45
26
376
176
1574
1.53
1.78
4.9
4.3
2.26
1.99
mu/l
1.99
170
1488
5
14
3.60
1.61
1.0
1.1
310.20
295.00
mg/l
—
5
14
105
871
1.37
1.52
16.7
16.6
1.23
1.23
mmol/l
0.14
100
834
29
187
1.62
1.50
24.4
18.8
105.97
105.66
mmol/l
0.22
29
187
109
911
1.37
1.50
14.3
14.5
1.23
1.23
mmol/l
0.31
100
848
9
37
2.47
1.49
5.1
6.6
—
—
—
0
0
55
411
1.43
1.46
1.7
1.5
94.28
96.65
pmol/l
0.16
25
206
31
205
1.58
1.46
2.5
2.3
—
—
—
0
0
162
1448
1.41
1.44
4.2
3.8
14.65
14.42
pmol/l
0.59
151
1297
49
361
1.44
1.40
4.5
3.9
7.38
7.38
ph
0.04
27
238
117
997
1.35
1.39
5.9
5.8
129.63
126.50
u/l
0.15
111
944
13
68
1.95
1.33
1.5
1.9
—
—
—
0
0
70
555
1.37
1.31
8.3
10.3
39.02
37.99
g/l
0.85
70
533
193
1793
1.53
1.29
8.8
8.4
—
—
—
0
0
108
922
1.32
1.21
8.8
13.1
—
—
—
0
0
8
39
2.07
1.15
14.6
7.7
37.00
36.97
°c
—
8
39
138
1229
1.30
1.09
8.8
13.1
0.20
0.21
e9/l
0.25
118
1018
22
317
0.65
1.09
2.1
1.7
—
—
—
0
0
5
21
2.39
1.08
5.4
2.8
401.20
966.81
u/ml
—
5
21
15
90
1.70
1.04
15.6
23.8
0.73
0.66
%
0.48
15
90
5
22
2.28
1.03
1.2
1.0
—
—
—
0
0
7
35
2.01
1.00
1.0
1.0
—
—
—
0
0
60
484
1.31
0.99
2.4
4.1
—
—
—
0
0
18
116
1.59
0.97
8.9
10.1
144.08
341.80
mg/l
2.54
13
100
7
36
1.96
0.97
4.3
4.6
7.41
7.39
ph
—
7
36
15
93
1.64
0.94
15.6
23.1
0.96
0.96
%
0.01
15
93
15
93
1.64
0.94
15.6
23.1
96.10
95.88
%
0.06
15
93
6
28
2.15
0.91
4.7
4.8
9.28
9.27
kpa
—
6
28
6
28
2.15
0.91
4.7
4.8
5.25
4.86
kpa
—
6
28
6
29
2.08
0.89
1.0
1.0
1.40
1.48
g/l
—
6
29
15
95
1.61
0.87
15.6
22.4
22.53
24.11
mmol/l
1.11
15
95
75
633
1.26
0.87
3.0
4.0
—
—
estimate
—
0
0
87
748
1.25
0.86
6.2
10.9
—
—
—
0
0
195
1845
1.41
0.86
11.8
12.9
23.02
23.54
mg/l
0.07
139
1316
11
64
1.74
0.85
6.4
4.1
—
—
—
0
0
6
113
0.51
0.85
1.0
1.1
—
—
—
0
0
139
1261
1.25
0.84
10.1
13.9
3.51
3.44
e9/l
0.13
117
1021
13
197
0.63
0.82
2.5
2.0
—
—
—
0
0
53
432
1.28
0.81
5.5
2.8
1.02
1.02
kg/l
1.64
38
259
21
148
1.45
0.78
1.7
1.7
357.04
392.49
mu/l
0.26
21
142
11
66
1.69
0.78
1.9
1.7
0.36
0.64
g/l
0.88
11
57
48
389
1.29
0.77
6.2
3.4
0.00
0.00
estimate
—
10
141
5
23
2.18
0.76
1.0
1.3
—
—
—
0
0
7
40
1.76
0.71
4.9
2.8
22.79
19.07
mmol/l
—
7
40
5
26
1.93
0.70
2.8
3.8
—
250.03
—
0
6
16
110
1.48
0.68
1.9
2.9
5.21
5.18
pmol/l
0.04
16
103
5
94
0.52
0.68
1.0
1.0
—
—
—
0
0
19
136
1.42
0.67
1.1
1.3
—
—
—
0
0
7
44
1.60
0.65
1.3
1.9
—
—
—
0
0
6
100
0.58
0.64
1.5
1.2
—
—
—
0
0
5
29
1.73
0.63
1.0
1.0
—
—
—
0
0
5
29
1.73
0.63
1.0
1.0
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
0
19
0.00
0.60
0.0
2.3
—
—
—
0
0
0
19
0.00
0.60
0.0
8.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
130
1196
1.19
0.59
8.4
12.0
0.04
0.04
e9/l
0.12
108
964
13
182
0.69
0.59
1.4
2.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
19.00
—
0
7
0
23
0.00
0.58
0.0
1.3
—
21.00
—
0
6
8
54
1.49
0.57
11.8
9.1
25.45
95.15
mg/mmol
—
8
48
5
89
0.55
0.57
1.0
1.9
—
—
—
0
0
130
1199
1.18
0.56
8.4
11.9
0.56
0.56
e9/l
0.01
108
966
37
439
0.80
0.56
1.9
2.1
1.23
1.18
mmol/l
0.15
31
413
36
294
1.26
0.55
2.2
6.5
5.05
2.28
mg/l
0.46
23
214
24
300
0.77
0.55
1.5
1.9
—
—
—
0
0
6
99
0.59
0.53
1.5
1.2
—
—
—
0
0
82
732
1.18
0.52
5.0
3.4
6.37
6.32
ph
0.18
47
329
57
493
1.20
0.52
9.8
10.1
7.40
7.41
ph
0.66
49
377
125
1156
1.17
0.50
8.6
12.2
8.31
8.38
%
0.13
117
1112
211
2049
1.46
0.50
18.6
20.1
278.86
273.40
e9/l
0.50
205
1950
93
844
1.16
0.47
5.3
3.7
0.00
0.00
estimate
—
10
144
103
942
1.16
0.47
4.0
3.3
35.03
35.59
mmol/mol
0.27
96
896
8
116
0.67
0.47
4.8
3.5
—
—
—
0
0
7
49
1.43
0.46
2.4
1.3
—
—
—
0
0
20
249
0.78
0.45
1.8
1.9
—
—
—
0
0
28
228
1.25
0.45
2.1
2.2
11.93
14.00
ng/l
0.16
12
76
211
2052
1.43
0.45
18.6
20.0
4.68
4.59
e12/l
2.04
204
1948
7
50
1.40
0.45
2.4
1.3
5.73
6.06
g/l
—
7
43
7
50
1.40
0.45
2.4
1.3
1.56
2.22
g/l
—
7
43
7
50
1.40
0.45
2.4
1.3
0.49
0.39
g/l
—
7
40
211
2053
1.42
0.43
18.6
20.0
7.05
6.87
e9/l
0.52
206
1945
10
69
1.46
0.43
1.7
1.6
—
2.83
—
0
10
8
55
1.46
0.43
1.9
4.9
—
—
—
0
0
5
31
1.61
0.43
2.2
2.9
11.86
12.32
umol/l
—
5
31
40
341
1.20
0.43
1.3
1.6
—
—
—
0
0
92
841
1.14
0.42
5.3
3.7
0.00
0.00
estimate
—
10
147
0
15
0.00
0.41
0.0
2.7
—
4.85
—
0
15
5
34
1.47
0.40
2.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
5
35
1.43
0.39
1.4
4.3
0.20
0.63
index
—
5
35
44
383
1.17
0.38
5.1
5.2
—
—
—
0
0
5
36
1.39
0.38
1.2
1.2
—
—
—
0
0
123
1152
1.13
0.37
8.7
12.2
0.55
0.61
%
0.75
115
1114
123
1152
1.13
0.37
8.6
12.3
2.69
3.16
%
1.58
115
1111
128
1202
1.13
0.37
8.5
12.0
35.58
35.75
%
0.05
121
1167
92
847
1.13
0.37
5.3
3.8
0.00
0.00
estimate
—
10
143
9
70
1.29
0.37
5.0
4.2
1.25
1.24
mmol/l
—
9
60
24
284
0.82
0.37
1.7
1.9
—
—
—
0
0
14
107
1.32
0.36
34.6
19.5
0.66
0.54
%
0.68
14
107
6
44
1.36
0.34
3.7
5.1
455.83
453.82
umol/l
—
6
44
26
302
0.83
0.33
1.7
1.9
—
—
—
0
0
18
217
0.81
0.33
1.7
2.4
—
—
—
0
0
130
1229
1.12
0.32
8.4
11.8
2.42
2.33
e9/l
0.39
113
1024
26
300
0.84
0.31
1.7
1.9
—
—
—
0
0
7
98
0.70
0.31
1.1
1.1
—
—
—
0
0
61
553
1.13
0.31
5.5
2.9
0.00
0.01
estimate
—
5
124
26
299
0.84
0.30
1.7
1.9
—
—
—
0
0
12
93
1.30
0.29
1.6
2.5
49.29
52.35
%
0.60
12
93
14
171
0.80
0.29
2.4
1.9
120.90
146.50
u/ml
—
7
73
122
1155
1.11
0.28
10.2
14.5
0.00
0.01
e9/l
0.49
98
843
124
1175
1.11
0.28
8.6
11.9
49.70
48.83
%
0.32
117
1147
67
615
1.11
0.28
1.5
1.6
—
—
—
0
0
43
384
1.14
0.27
5.6
5.0
1.15
1.12
inr
0.23
34
315
8
64
1.25
0.27
1.5
1.4
—
—
—
0
0
8
64
1.25
0.27
2.4
1.2
—
233.35
—
0
17
8
64
1.25
0.27
1.5
1.5
—
—
—
0
0
8
65
1.23
0.27
39.3
27.0
12.49
11.56
%
—
8
65
176
1701
1.13
0.26
9.6
10.5
28.78
23.94
u/l
0.92
171
1643
48
434
1.12
0.25
3.4
2.4
—
—
—
0
0
21
178
1.19
0.25
1.4
1.6
—
—
—
0
0
5
39
1.28
0.23
1.8
2.5
5.38
6.00
mmol/l
—
5
32
5
39
1.28
0.23
2.2
3.8
3.12
3.15
e9/l
—
5
39
18
152
1.19
0.22
2.7
1.4
—
—
—
0
0
45
409
1.11
0.22
1.5
1.3
—
—
—
0
0
5
41
1.21
0.22
1.0
1.3
—
350.00
—
0
6
8
100
0.79
0.21
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
988.50
—
0
10
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
90
935
0.92
0.20
2.0
2.0
10.04
3.21
u/ml
0.74
18
168
47
431
1.10
0.20
8.4
10.0
—
—
—
0
0
29
259
1.13
0.19
1.8
1.5
192.00
438.89
titre
—
5
36
30
269
1.12
0.19
1.8
1.9
—
—
—
0
0
112
1071
1.07
0.18
3.9
3.9
51.68
50.01
ug/l
0.07
105
1025
16
137
1.17
0.18
1.8
1.5
—
—
—
0
0
50
464
1.09
0.17
11.9
13.8
—
—
—
0
0
56
589
0.92
0.17
2.2
2.4
—
—
—
0
0
11
91
1.21
0.16
8.5
4.9
13.82
14.81
%
0.11
11
91
35
320
1.10
0.16
4.3
5.0
—
—
—
0
0
9
80
1.12
0.15
1.1
1.3
—
—
—
0
0
9
81
1.11
0.15
9.2
5.0
40.21
37.89
%
—
9
81
9
81
1.11
0.15
1.3
1.3
—
—
—
0
0
28
254
1.11
0.15
6.2
5.4
9.14
8.67
g/l
0.26
28
246
13
148
0.86
0.14
2.2
2.3
—
—
—
0
0
12
102
1.18
0.14
2.5
1.5
1.18
1.17
g/l
0.07
12
97
25
226
1.11
0.14
3.3
6.0
63.68
60.06
e9/l
0.19
13
131
45
420
1.08
0.13
5.2
3.5
5.48
8.53
e6/l
0.90
38
371
10
84
1.19
0.13
8.9
4.6
27.00
27.20
%
—
10
84
10
85
1.17
0.11
34.8
22.7
74.32
69.16
%
—
10
85
16
176
0.89
0.11
2.3
2.7
24.62
31.03
u/l
0.68
16
143
96
979
0.95
0.11
14.2
9.9
5.68
5.97
mmol/l
1.31
90
913
51
482
1.06
0.11
11.2
12.3
23.33
23.46
mmol/l
0.16
51
482
11
124
0.87
0.10
2.2
2.1
—
—
—
0
0
10
86
1.16
0.10
8.7
4.8
14.50
9.02
%
—
10
86
10
86
1.16
0.10
8.7
4.8
68.20
69.48
%
—
10
86
38
397
0.94
0.10
3.2
3.4
553.57
600.38
mosm/kgh2o
0.73
30
347
39
407
0.94
0.09
3.6
4.5
2.92
2.40
e6/l
0.24
22
213
107
1084
0.96
0.09
5.4
4.1
36.00
162.61
e6/l
—
5
18
6
54
1.10
0.09
1.0
1.1
—
—
—
0
0
6
55
1.08
0.09
1.0
2.3
3.75
4.37
u/ml
—
6
55
45
427
1.06
0.08
1.7
1.9
—
—
—
0
0
68
695
0.96
0.08
1.9
2.0
—
—
—
0
0
76
733
1.04
0.08
3.3
2.3
—
—
—
0
0
6
74
0.80
0.07
1.2
1.1
—
—
—
0
0
7
80
0.86
0.07
1.0
6.2
294.29
427.72
mg/l
—
7
80
21
222
0.93
0.07
1.8
4.2
3035.18
1135.83
ng/l
0.53
11
123
59
568
1.04
0.06
2.6
3.7
2.38
2.37
mg/l
0.01
52
508
60
612
0.96
0.06
4.4
4.7
0.20
0.29
e6/l
0.36
44
435
36
342
1.05
0.06
2.6
1.8
—
—
—
0
0
10
110
0.90
0.06
4.2
7.1
0.20
0.03
%
—
5
37
20
187
1.07
0.05
1.1
1.2
2.01
9.10
u/ml
—
9
59
31
295
1.05
0.05
1.5
1.8
—
—
—
0
0
111
1085
1.03
0.05
3.2
2.3
5.31
5.30
mmol/l
0.06
103
987
39
399
0.96
0.04
4.3
2.8
0.00
0.00
estimate
—
6
122
10
91
1.09
0.03
1.5
1.7
—
—
—
0
0
22
209
1.05
0.03
1.0
1.3
0.47
0.94
u/ml
0.59
16
156
18
187
0.95
0.03
1.6
2.1
—
—
—
0
0
12
127
0.93
0.03
1.0
1.2
—
—
—
0
0
68
664
1.02
0.02
5.4
4.8
21.93
28.26
e6/l
0.29
52
484
51
497
1.02
0.02
14.8
12.7
0.57
0.85
mmol/l
0.25
40
411
12
126
0.94
0.02
2.2
2.1
—
25.40
—
0
5
79
789
0.99
0.00
6.6
5.8
100.76
51.27
e6/l
0.39
52
501
51
500
1.01
0.00
15.3
12.8
7.37
7.37
ph
0.20
34
331
12
123
0.97
0.00
2.1
2.2
122.33
91.13
au/ml
—
6
52
40
397
1.00
0.00
1.7
2.0
—
—
—
0
0
23
225
1.01
0.00
4.8
2.5
5204.14
5777.71
u/l
—
7
58
89
881
1.00
0.00
2.5
1.9
1.57
1.46
g/l
0.42
48
461
57
561
1.01
0.00
16.2
17.5
24.82
24.86
mmol/l
0.04
57
561
12
124
0.96
0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
26.00
—
0
8
0
9
0.00
0.00
0.0
2.2
—
3.81
—
0
9
6
59
1.01
0.00
1.5
2.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1.14
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
54.80
—
0
5
0
5
0.00
-0.00
0.0
5.2
—
31.80
—
0
5
8
79
1.00
-0.00
39.9
23.8
75.75
69.54
%
—
8
79
0
5
0.00
-0.00
0.0
1.6
—
50.60
—
0
5
0
5
0.00
-0.00
0.0
5.4
—
12.00
—
0
5
6
65
0.91
-0.00
1.3
1.5
60.72
14.42
u/ml
—
6
55
0
5
0.00
-0.00
0.0
1.2
—
6.44
—
0
5
8
88
0.90
-0.00
3.1
2.3
—
—
—
0
0
8
79
1.00
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
45.40
—
0
6
7
77
0.90
-0.00
1.0
1.3
—
—
—
0
0
5
54
0.92
-0.00
1.8
1.4
401.60
340.03
ug/g
—
5
31
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
88
0.90
-0.00
3.1
2.2
—
—
—
0
0
5
56
0.88
-0.00
1.0
5.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
227.00
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
75
0.92
-0.00
1.0
6.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
8
88
0.90
-0.00
3.1
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
2050.00
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
76.80
—
0
5
8
88
0.90
-0.00
3.1
2.3
—
—
—
0
0
6
68
0.87
-0.00
1.0
6.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
15.0
—
92.43
—
0
7

Mortality – FinRegistry

Association

Association between endpoint P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION and mortality.

Females

Parameter HR [95% CI] p-value
P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION 6.474 [4.98, 8.41] < 0.001
Birth year 0.997 [0.99, 1.0] 0.407

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 6317 females with P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION died.

Males

Parameter HR [95% CI] p-value
P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION 3.741 [2.92, 4.79] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 5727 males with P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION died.

Mortality risk

Mortality risk for people of age

years, who have P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION.

N-year risk Females Males
1 0.569% 0.49%
5 3.842% 3.819%
10 8.574% 10.069%
15 17.236% 18.695%
20 30.123% 31.154%

Relationships between endpoints

Index endpoint: P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION – Slow fetal growth and fetal malnutrition

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data