Oral leukoplakia, including avohilmo

K11_ORAL_LEUCOPLACIA_INCLAVO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

3 out of 7 registries used, show all original rules.

1153

4. Check minimum number of events

None

1153

5. Include endpoints

None

1153

6. Filter based on genotype QC (FinnGen only)

1052

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5452 2705 2719
Only index persons 5235 2615 2620
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.10 0.10
Median age at first event (years)
Whole population 57.42 59.83 55.09
Only index persons 57.24 59.67 54.82

-FinnGen-

Key figures

All Female Male
Number of individuals 1052 534 518
Unadjusted period prevalence (%) 0.21 0.19 0.24
Median age at first event (years) 58.43 58.45 58.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1081
Matched controls
10810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
61.3
307.7
333
78
K13.29
ICD-10 Finland
Indefinite leukoplakia
66.5
307.7
214
40
K13.20
ICD-10 Finland
Idiopathic leukoplakia
+∞
307.7
693
*
K13.21
ICD-10 Finland
Leukoplakia caused by tobacco
+∞
307.7
423
*
EKA10
NOMESCO Finland
iopsy of buccal mucosa
34.3
307.7
258
98
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
20.2
263.7
215
131
ECA20
NOMESCO Finland
Biopsy of gingiva
45.9
211.4
126
31
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
15.6
209.4
194
149
K13.78
ICD-10 Finland
Other change in the oral mucosa
16.8
181.1
159
110
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
64.6
160.8
89
15
SXA10
NOMESCO Finland
Oral mucosal sampling
24.9
155.5
112
50
SAA03
NOMESCO Finland
Extended examination of mouth
4.8
138.7
703
3008
EJ2S1
NOMESCO Finland
Photography of oral mucosa
26.3
133.9
94
39
EJB10
NOMESCO Finland
Excision of tumor or other lesion of apex or body of tongue
46.8
111.8
66
15
SBA00
NOMESCO Finland
Microbiological examinations
11.7
109.2
117
111
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
14.6
107.9
100
75
L43.8
ICD-10 Finland
Other lichen planus
13.8
104.7
100
79
EHA10
NOMESCO Finland
Biopsy of palate
30.0
97.4
65
23
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
38.2
93.5
58
16
WZC00
NOMESCO Finland
Treatment plan or consultation
3.3
81.7
590
2880
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
3.2
76.9
485
2167
A07AA02
ATC
nystatin; oral
5.4
70.5
152
317
SAA02
NOMESCO Finland
Basic examination of mouth
3.6
65.7
869
5735
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.9
62.9
602
3289
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.7
62.4
125
243
B37.08
ICD-10 Finland
Other candidal stomatitis
17.0
61.9
52
32
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.7
58.9
118
229
K05.31
ICD-10 Finland
Periodontitis pronounced
3.4
54.1
236
823
SAA04
NOMESCO Finland
Special examination of mouth
4.9
53.2
125
279
L43.9
ICD-10 Finland
Lichen planus, unspecified
7.6
50.9
74
103
TEA00
NOMESCO Finland
Biopsy of lip
12.8
49.0
48
39
SAA01
NOMESCO Finland
Simple examination of mouth
3.2
48.6
892
6439
N07BA03
ATC
varenicline; oral
4.8
47.6
115
262
WX110
NOMESCO Finland
Infiltration anesthesia
3.0
44.0
882
6464
SDA03
NOMESCO Finland
Periodontal treatment
2.4
41.7
549
3285
SDA04
NOMESCO Finland
Demanding periodontal treatment
2.4
39.7
414
2227
Z01.2
ICD-10 Finland
Dental examination
2.3
38.9
590
3713
SFA10
NOMESCO Finland
One-surface restoration
2.3
36.6
687
4674
K13.2
ICD-10 Finland
Leukoplakia and other disturbances of oral epithelium, including tongue
49.6
35.9
43
9
K13.22
ICD-10 Finland
Erythroplakia of oral epithelium, including tongue
69.1
35.2
40
6
Z72.0
ICD-10 Finland
Tobacco use
5.4
34.2
69
134
K02.1
ICD-10 Finland
Caries of dentine
2.2
34.0
712
4998
EBA00
NOMESCO Finland
Extraction of tooth
2.1
31.5
472
2881
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.1
31.2
672
4697
A01AC01
ATC
triamcinolone; local oral
7.8
30.7
43
57
D20
ICPC
Mouth/tongue/lip symptom/complaint
4.0
30.7
92
246
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.6
30.5
200
855
SFA20
NOMESCO Finland
Two-surface restoration
2.1
29.8
700
5015
K05.30
ICD-10 Finland
Periodontitis complex
2.4
28.6
230
1080
A01AB09
ATC
miconazole; local oral
3.0
28.4
137
497
WZA90
NOMESCO Finland
Other medical or dental certificate
2.2
27.6
312
1690
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.9
27.4
50
88
GBB00
NOMESCO Finland
Tracheostomy
7.5
26.4
38
52
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.2
26.3
111
372
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
8.2
26.1
35
44
WX290
NOMESCO Finland
Other blockage of nerve
2.0
25.6
561
3838
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.2
25.1
286
1547
K13.6
ICD-10 Finland
Irritative hyperplasia of oral mucosa
7.9
24.8
34
44
D82
ICPC
Teeth/gum disease
1.9
24.0
447
2875
P17
ICPC
Tobacco abuse
7.1
23.9
36
52
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
88.8
23.7
26
*
SFA30
NOMESCO Finland
Three-surface restoration
1.9
23.6
529
3612
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.9
23.2
424
2703
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
55.3
23.1
27
5
SXC03
NOMESCO Finland
Other oral or dental procedure
7.1
22.6
34
49
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.0
22.5
302
1727
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
22.4
543
3780
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.9
22.4
537
3727
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
8.5
22.3
29
35
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.1
22.2
99
342
S01.50
ICD-10 Finland
Open wound in oral cavity
9.2
22.1
27
30
K03.64
ICD-10 Finland
Dental calculus supragingival
1.9
21.7
379
2369
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.4
21.1
35
56
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.4
21.0
154
687
K02.0
ICD-10 Finland
Caries limited to enamel
2.1
20.1
230
1233
ZXC10
NOMESCO Finland
Use of laser
4.6
19.8
47
105
K13.24
ICD-10 Finland
Gum problems in smokers
203.6
19.6
20
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
15.2
19.0
31
21
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
7.5
18.7
27
37
EBA10
NOMESCO Finland
Operative extraction of tooth
2.3
18.4
150
700
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.8
18.2
503
3571
D07AD01
ATC
clobetasol; topical
2.1
18.0
211
1139
EB1VA, ,
NOMESCO Finland
2.0
17.9
232
1298
ECA30
NOMESCO Finland
Excision of lesion of gingiva
7.4
17.9
26
36
EJB40
NOMESCO Finland
Hemiglossectomy
67.8
17.8
20
*
EJW99
NOMESCO Finland
Other operation on tongue or floor of mouth
182.9
17.6
18
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
15.9
17.5
28
18
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
17.5
565
4175
EKB00
NOMESCO Finland
Excision of tumour or other lesion of cheek
14.2
17.3
29
21
SXC05
NOMESCO Finland
Other oral or dental procedure
2.9
17.1
85
312
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.8
17.1
315
1976
SBB10
NOMESCO Finland
Dental impressions
2.9
17.1
86
318
SAE01, ,
NOMESCO Finland
5.1
17.0
36
73
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.9
16.3
49
131
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
4.9
16.2
36
76
D07AC01
ATC
betamethasone; topical
1.7
16.2
416
2867
EJB30
NOMESCO Finland
Excision of tumor or other lesion of floor of the mouth
24.9
16.0
22
9
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.8
15.8
322
2075
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
7.3
15.7
23
32
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.8
15.6
357
2374
SCA01
NOMESCO Finland
Preventive oral health care, short
1.8
15.5
308
1968
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
12.6
15.4
27
22
K03.66
ICD-10 Finland
Tooth plaque
2.4
15.3
109
478
B37.03
ICD-10 Finland
Chronic atrophic candida infection in the mouth
18.0
15.2
23
13
EDB00
NOMESCO Finland
Partial excision of mandible
45.7
15.1
18
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
14.2
15.1
25
18
B37.02
ICD-10 Finland
Chronic hyperplastic candidal stomatitis
81.2
14.6
16
*
A01AB04
ATC
amphotericin B; local oral
2.9
14.5
69
247
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
14.5
261
1615
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.8
14.3
281
1782
K12.18
ICD-10 Finland
Other forms of stomatitis
12.2
14.1
25
21
8070/3-C02.9
ICD-O-3
Squamous cell carcinoma, NOS, of tongue, NOS
54.1
13.8
16
*
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
3.6
13.7
46
133
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
76.1
13.6
15
*
J02AC01
ATC
fluconazole; systemic
1.7
13.6
397
2801
EJ1S1
NOMESCO Finland
Photography of tongue
16.5
13.5
21
13
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.0
13.3
61
214
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.5
13.1
45
132
N06AX11
ATC
mirtazapine; oral
1.7
13.1
386
2721
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
13.0
327
2212
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.1
13.0
124
615
C04.0
ICD-10 Finland
Malignant neoplasm: Anterior floor of mouth
28.7
13.0
17
6
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.3
12.7
47
145
N05AH04
ATC
quetiapine; oral
1.8
12.6
203
1207
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.7
12.3
270
1756
JDB10
NOMESCO Finland
Percutaneous gastrostomy
5.2
12.2
25
49
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
12.0
234
1471
SPAT1301
SPAT
No procedures
1.6
11.9
327
2255
KMAK, ,
NOMESCO Finland
1.6
11.9
532
4121
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.4
11.9
23
43
L43.0
ICD-10 Finland
Hypertrophic lichen planus
9.8
11.8
23
24
N05BA01
ATC
diazepam; systemic, rectal
1.9
11.3
154
868
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.1
11.3
116
592
N05AA02
ATC
levomepromazine; systemic
2.8
11.2
56
206
C02.10
ICD-10 Finland
Malignant neoplasm of tip of tongue
43.8
10.9
13
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
10.9
59
227
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.0
10.8
116
601
N02BF02
ATC
pregabalin; oral
2.3
10.8
87
403
S29
ICPC
Skin symptom/complaint other
1.7
10.6
222
1420
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
10.6
92
439
K12.10
ICD-10 Finland
Stomatitis NOS
11.4
10.6
19
17
EAA10
NOMESCO Finland
Excision of lesion of lip
5.1
10.5
22
44
ZZA00
NOMESCO Finland
Split skin graft
3.2
10.5
42
136
K13.1
ICD-10 Finland
Cheek and lip biting
9.3
10.5
21
23
N07BB01
ATC
disulfiram; oral
2.6
10.5
62
249
N05CD07
ATC
temazepam; oral
1.9
10.5
135
745
C02.2
ICD-10 Finland
Malignant neoplasm: Ventral surface of tongue
111.1
10.4
11
*
8070/3-C06.0
ICD-O-3
Squamous cell carcinoma, NOS, of cheeck mucosa
+∞
10.4
10
*
L84
ICD-10 Finland
Corns and callosities
2.9
10.4
49
175
B37.01
ICD-10 Finland
Acute athrophy candidal stomatitis
16.2
10.4
16
10
J01FF01
ATC
clindamycin; systemic
1.6
10.3
298
2068
E0000UV, ,
ATC
1.5
10.3
434
3283
VALMI, ,
NOMESCO Finland
1.7
10.3
242
1595
SAE02, ,
NOMESCO Finland
4.8
10.3
23
49
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
10.3
156
909
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
10.2
91
439
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.9
10.2
29
75
ECB00
NOMESCO Finland
Suture of gingiva
2.8
10.0
50
184
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
10.0
173
1047
-1, ,
NOMESCO Finland
1.6
9.9
339
2443
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.2
9.9
26
63
L43.3
ICD-10 Finland
Subacute (active) lichen planus
16.9
9.9
15
9
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.2
9.8
39
126
L43
ICD-10 Finland
Lichen planus
4.6
9.8
23
51
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
4.2
9.7
25
60
J01DB01
ATC
cefalexin; oral
1.7
9.6
876
7783
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
4.5
9.6
23
52
K08.3
ICD-10 Finland
Retained dental root
2.1
9.6
99
506
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.8
9.6
147
859
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
10.1
9.5
18
18
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.8
9.4
140
809
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
9.4
97
495
K14.9
ICD-10 Finland
Disease of tongue, unspecified
12.5
9.4
16
13
M54.5
ICD-10 Finland
Low back pain
1.5
9.3
393
2960
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
9.2
695
5886
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.3
9.2
23
54
R95
ICPC
Chron obstructive pulmonary disease
2.9
9.1
42
148
SFC92
NOMESCO Finland
Other complicated additional procedure necessary for restorative treatment
2.2
9.1
81
390
GD1AD
NOMESCO Finland
Thorax CT examination
2.1
9.1
83
404
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.1
363
2700
XQ802
NOMESCO Finland
Epicutan test
2.7
9.0
48
183
SDA05
NOMESCO Finland
Very demanding periodontal treatment
2.1
9.0
85
419
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.7
8.9
48
184
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
8.9
108
584
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.9
316
2289
K04.09
ICD-10 Finland
Pulpit UNS
2.5
8.8
56
234
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
8.8
80
390
N05BA04
ATC
oxazepam; oral
1.6
8.7
273
1920
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.7
316
2298
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
8.7
100
531
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
3.2
8.7
33
104
SPF20
NOMESCO Finland
Temporary relining of dentures
7.7
8.7
19
25
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.6
8.7
51
205
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
8.6
189
1220
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
8.5
54
225
N05AB01
ATC
dixyrazine; systemic
4.4
8.4
21
49
8070/3-C03.1
ICD-O-3
Squamous cell carcinoma, NOS, of lower gum
90.7
8.4
9
*
EMAK, ,
NOMESCO Finland
2.6
8.4
49
196
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.4
469
3715
R03BB04
ATC
tiotropium bromide; inhalant
1.9
8.4
112
626
H02AB06
ATC
prednisolone; systemic
1.5
8.3
499
4009
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
2.4
8.2
53
223
SFA00
NOMESCO Finland
Small restoration
1.7
8.1
152
941
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.7
8.0
25
69
E000001, ,
ATC
1.6
8.0
193
1273
EJB99
NOMESCO Finland
Other excision on tongue and floor of mouth
22.2
8.0
11
5
SBA10
NOMESCO Finland
Measurement of salivary flow rate
4.2
8.0
21
51
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.9
8.0
36
126
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
8.0
187
1227
K03.00
ICD-10 Finland
Approximal wear
2.0
7.9
87
456
WX199
NOMESCO Finland
Other local analgesia
2.6
7.8
43
167
N02AA05
ATC
oxycodone; systemic
1.6
7.8
199
1333
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
45.3
7.7
9
*
EKC00
NOMESCO Finland
Suture of cheek
45.3
7.7
9
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
7.7
144
889
K05.18
ICD-10 Finland
Chronic gingivitis
2.0
7.6
83
432
S10
ICPC
Boil/carbuncle
2.1
7.6
69
336
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.6
7.6
42
164
SPD01
NOMESCO Finland
Mucosa-supported complete denture
4.1
7.6
20
49
R03AC02
ATC
salbutamol; inhalant
1.4
7.5
559
4635
N06AB04
ATC
citalopram; systemic
1.6
7.5
215
1476
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.3
7.5
56
251
SGA01
NOMESCO Finland
Emergency treatment
1.6
7.5
170
1103
SPAT1260
SPAT
Consultation of another employee
1.6
7.5
176
1152
SPAT1240
SPAT
Therapeutic discussion
1.9
7.5
99
550
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.5
234
1638
SCF03
NOMESCO Finland
Preventive oral care by dental hygienist, extensive
3.9
7.5
21
54
Q38.61
ICD-10 Finland
Leukokeratos in the mouth
80.6
7.4
8
*
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.3
7.4
27
83
EBB10
NOMESCO Finland
Insertion of dental implant
4.1
7.4
20
50
SPAT1263
SPAT
Sampling
1.4
7.3
405
3179
A97
ICPC
No disease
1.6
7.3
207
1419
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
7.2
192
1297
L17
ICPC
Foot/toe symptom/complaint
1.5
7.2
321
2419
K04.1
ICD-10 Finland
Necrosis of pulp
1.8
7.2
121
725
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
7.2
84
449
N05AA01
ATC
chlorpromazine; systemic, rectal
4.0
7.2
20
51
SPE90
NOMESCO Finland
Other partial denture
3.2
7.2
28
90
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.5
7.2
43
175
WYA10
NOMESCO Finland
Emergency care or similar visit
2.0
7.1
76
393
N02AX02
ATC
tramadol; systemic, rectal
1.4
7.1
459
3701
R96
ICPC
Asthma
1.8
7.1
107
621
K14.61
ICD-10 Finland
Glossodynia
5.7
7.1
19
34
D11
ICPC
Diarrhoea
1.8
7.1
119
713
B37.0
ICD-10 Finland
Candidal stomatitis
4.2
7.0
18
43
N06AX12
ATC
bupropion; oral
2.0
7.0
71
361
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.0
237
1689
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.0
257
1863
M48.0
ICD-10 Finland
Spinal stenosis
1.7
7.0
141
889
R02
ICPC
Shortness of breath/dyspnoea
1.7
6.9
143
906
SPE02
NOMESCO Finland
Metal-framed partial denture
3.1
6.9
28
92
N02BE01
ATC
paracetamol; systemic, rectal
1.7
6.9
951
8808
N05CF01
ATC
zopiclone; oral
1.4
6.8
330
2521
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
6.8
79
422
L43.1
ICD-10 Finland
Bullous lichen planus
40.3
6.8
8
*
8070/3-C06.9
ICD-O-3
Squamous cell carcinoma, NOS, of mouth, NOS
40.3
6.8
8
*
Z04.3
ICD-10 Finland
Examination and observation following other accident
3.2
6.7
26
83
L03
ICPC
Low back symptom/complaint
1.5
6.7
296
2221
K11.70
ICD-10 Finland
Hypoptyalism
7.2
6.7
15
21
N06AX21
ATC
duloxetine; oral
1.7
6.7
125
772
K05.38
ICD-10 Finland
Other chronic periodontitis
2.5
6.7
41
169
K03.0
ICD-10 Finland
Excessive attrition of teeth
2.6
6.7
37
145
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.6
523
4348
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.6
136
861
ECB20
NOMESCO Finland
Oral alveoplasty
3.9
6.6
19
50
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
10.1
6.5
12
12
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
6.5
77
413
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
6.5
54
254
P99
ICPC
Psychological disorders other
2.6
6.5
35
135
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
6.5
125
778
R74
ICPC
Upper respiratory infection acute
1.4
6.5
300
2270
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
6.4
133
843
EN1CD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
70.3
6.4
7
*
SAA03, ,
SPAT
70.3
6.4
7
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.4
186
1279
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
6.4
195
1355
K11.2
ICD-10 Finland
Sialoadenitis
2.5
6.4
38
154
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
3.8
6.4
19
51
F41.00
ICD-10 Finland
Moderate panic disorder
4.1
6.4
17
42
J01DA01
ATC
[U] cefalexin
1.4
6.4
622
5343
K08.80
ICD-10 Finland
Toothache NOS
1.8
6.4
95
550
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.4
113
688
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.3
269
2002
V03AA01, ,
ATC
3.2
6.3
24
76
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.3
196
1368
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.3
104
620
K13.03
ICD-10 Finland
Keilit UNS
9.3
6.3
12
13
K59.09
ICD-10 Finland
Constipation, unspecified
1.9
6.3
74
397
K03.61
ICD-10 Finland
Coatings in tobacco smokers
18.1
6.3
9
5
C02.9
ICD-10 Finland
Malignant neoplasm: Tongue, unspecified
+∞
6.3
6
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.2
193
1348
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.2
6.2
24
77
L73.2
ICD-10 Finland
Hidradenitis suppurativa
4.0
6.2
17
43
N03AE01
ATC
clonazepam; systemic
2.0
6.1
62
315
L01
ICPC
Neck symptom/complaint
1.6
6.1
162
1090
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
6.1
77
422
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.1
397
3183
A02BC01
ATC
omeprazole; systemic
1.4
6.1
264
1971
SPAT1058
SPAT
PEF monitoring instruction
1.8
6.1
83
468
SXA20
NOMESCO Finland
Local application of medicine to mouth
2.1
6.1
59
296
EB1S1
NOMESCO Finland
Photography of teeth
6.7
6.0
14
21

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
191
898
2.37
23.34
4.0
4.5
7.38
7.36
ph
0.67
131
654
229
1189
2.17
21.96
5.4
5.0
30.90
31.99
%
0.70
143
774
238
1276
2.11
20.92
1.8
1.4
—
—
—
0
0
527
3781
1.77
18.45
2.7
2.2
—
—
—
0
0
630
4986
1.63
13.53
8.1
7.8
1.21
1.21
mmol/l
0.57
542
4331
259
1642
1.76
13.06
1.7
1.7
1138.46
1217.74
nmol/l
0.68
189
1251
705
5782
1.63
12.71
5.5
5.5
6.93
6.73
mmol/l
1.56
674
5521
589
4642
1.59
12.41
14.3
14.2
1.20
1.23
inr
1.03
490
3850
574
4506
1.58
12.23
7.3
7.1
1.21
1.21
mmol/l
0.05
523
4173
433
3187
1.60
12.12
2.4
2.2
245.20
216.68
u/l
0.21
404
3037
563
4416
1.57
11.92
2.2
2.1
94.27
96.04
pmol/l
0.38
283
2321
762
6487
1.59
10.69
4.3
3.4
50.65
52.97
u/l
0.34
699
6113
560
4456
1.53
10.64
5.1
5.3
35.47
35.66
g/l
0.34
523
4197
952
8600
1.90
10.60
6.5
5.3
1.93
1.93
mu/l
0.00
865
7951
644
5296
1.53
10.40
6.4
6.9
10.63
11.59
umol/l
1.39
611
5077
439
3347
1.52
9.98
7.5
6.4
—
—
—
0
0
417
3181
1.51
9.27
3.1
2.7
55.21
87.61
u/l
0.70
385
2955
186
1174
1.71
9.25
1.8
1.7
—
—
—
0
0
845
7477
1.60
9.03
9.5
8.7
79.37
79.67
u/l
0.07
804
7118
823
7241
1.57
8.99
5.1
4.3
14.99
14.86
pmol/l
0.71
731
6651
88
452
2.03
8.40
4.5
3.8
—
—
—
0
0
327
2417
1.51
8.26
2.6
2.4
—
—
—
0
0
551
4512
1.45
8.23
3.0
2.8
—
—
estimate
—
0
0
72
349
2.14
8.01
4.6
4.0
24.88
24.87
mmol/l
0.01
65
328
1018
9563
2.11
7.83
23.9
19.7
139.27
139.71
mmol/l
5.27
997
9392
559
4617
1.44
7.82
7.8
6.6
58.03
57.08
%
1.11
523
4424
1019
9580
2.11
7.75
23.9
19.9
4.00
3.98
mmol/l
1.09
996
9396
89
487
1.90
7.10
2.1
2.3
0.00
1.63
estimate
0.50
18
154
17
39
4.41
6.97
5.1
2.5
0.61
0.61
mmol/l
0.07
17
39
187
1267
1.58
6.91
3.0
3.4
5.00
4.49
e9/l
0.35
145
1109
709
6187
1.42
6.87
5.3
4.7
1266.44
1721.10
e6/l
—
9
94
964
8970
1.69
6.69
7.6
6.6
40.21
39.61
mmol/mol
1.11
891
8421
986
9232
1.77
6.68
20.8
16.6
22.94
24.50
mg/l
0.88
854
7680
531
4430
1.39
6.57
2.7
2.5
75.76
77.55
nmol/l
0.77
467
3988
597
5098
1.38
6.31
7.9
6.6
1.90
1.95
e9/l
0.38
539
4469
589
5029
1.38
6.17
7.7
6.5
0.05
0.04
e9/l
1.52
521
4291
548
4625
1.37
6.17
8.4
6.8
8.92
8.99
%
0.21
508
4350
603
5172
1.38
6.12
8.0
6.8
0.20
0.19
e9/l
0.33
536
4507
293
3740
0.70
6.08
3.1
3.3
—
—
—
0
0
587
5017
1.37
6.07
7.7
6.5
0.61
0.59
e9/l
1.71
519
4277
357
2817
1.40
6.02
4.5
4.4
—
—
—
0
0
396
3181
1.39
6.00
2.8
2.5
—
—
—
0
0
546
4622
1.37
5.95
8.1
6.7
2.85
2.90
%
0.22
508
4343
323
2510
1.41
5.94
2.3
2.2
2.77
2.94
mg/l
0.51
272
2167
545
4617
1.36
5.89
8.4
6.8
0.72
0.70
%
0.59
506
4332
437
3576
1.37
5.88
4.1
3.5
7.32
7.62
mmol/l
0.67
356
3059
554
4711
1.36
5.82
8.0
6.7
27.08
27.56
%
0.47
526
4475
418
3409
1.37
5.70
3.7
3.6
30.22
49.66
mg/l
2.54
250
2196
1029
9824
1.99
5.65
15.2
12.7
26.59
27.06
u/l
0.44
1000
9560
641
5593
1.36
5.61
11.1
10.1
4.44
4.10
e9/l
2.68
576
4871
151
1028
1.55
5.42
2.2
2.2
0.21
0.21
g/l
0.25
144
959
141
948
1.56
5.35
2.0
2.2
0.00
0.02
estimate
0.50
16
191
360
2891
1.37
5.33
1.9
1.7
18.63
20.10
nmol/l
1.24
298
2447
24
85
2.86
5.27
1.3
1.3
29.83
30.80
u/l
0.04
19
70
105
665
1.64
5.11
4.4
3.6
5.28
5.15
kpa
0.89
98
646
1032
9898
1.94
5.03
26.0
21.8
76.05
78.50
umol/l
2.01
1015
9799
35
154
2.32
5.00
5.7
6.1
378.45
365.02
umol/l
0.25
29
137
168
1193
1.48
4.94
2.4
2.5
108.15
130.92
ug/g
0.74
134
970
419
3478
1.33
4.90
4.2
4.2
5.16
9.19
mg/mmol
2.57
239
2175
102
650
1.63
4.85
4.4
3.6
7.41
7.42
ph
0.34
82
555
355
2881
1.35
4.81
3.6
3.2
—
—
—
0
0
462
3903
1.32
4.73
4.0
3.8
28.71
60.47
ng/l
1.18
337
2863
75
450
1.72
4.49
1.3
1.3
—
—
—
0
0
169
1224
1.45
4.48
7.3
9.2
11.99
12.11
kpa
0.12
164
1186
168
1217
1.45
4.45
7.4
9.3
7.41
7.41
ph
0.01
113
686
209
1579
1.40
4.39
2.7
2.6
2.33
2.30
g/l
0.43
195
1469
1042
10066
1.97
4.34
32.3
25.2
253.45
248.19
e9/l
1.70
1018
9883
166
1207
1.44
4.31
7.3
9.3
1.49
1.00
mmol/l
0.91
127
1009
1042
10068
1.97
4.30
32.1
25.1
92.00
91.29
fl
5.67
1026
9969
1042
10069
1.97
4.29
32.1
25.1
30.68
30.41
pg
5.09
1026
9970
962
9113
1.51
4.28
6.0
5.3
6.09
5.99
mmol/l
1.14
873
8383
1042
10070
1.96
4.27
32.8
25.7
40.37
40.64
%
0.81
1025
9965
1042
10070
1.96
4.27
32.2
25.2
7.16
6.71
e9/l
4.45
1016
9855
1042
10070
1.96
4.27
32.2
25.2
4.45
4.51
e12/l
3.50
1016
9859
1042
10073
1.95
4.22
32.4
25.3
135.72
136.18
g/l
0.44
1028
9974
247
1957
1.34
3.82
4.3
4.1
1041.96
426.64
ng/l
0.34
190
1561
218
1699
1.35
3.75
2.6
2.6
12.36
13.12
umol/l
0.87
203
1583
284
2306
1.31
3.69
4.8
4.0
1.02
1.02
kg/l
0.01
194
1536
271
2187
1.32
3.68
1.3
1.3
1.72
1.51
u/ml
0.10
75
613
938
8893
1.41
3.65
5.1
4.5
1.49
1.32
mmol/l
1.55
846
8184
126
899
1.45
3.62
2.3
3.0
72.97
71.33
e9/l
0.14
103
657
196
1517
1.36
3.52
2.2
2.1
—
—
—
0
0
988
9475
1.50
3.44
6.8
6.1
2.63
2.71
mmol/l
1.71
910
8818
404
3460
1.27
3.43
3.2
3.6
2.35
2.36
mmol/l
0.19
357
3149
129
939
1.42
3.34
6.8
7.8
8.04
9.83
mmol/l
2.75
124
903
106
744
1.47
3.32
2.8
3.1
184.93
203.52
ng/l
0.24
98
683
240
1932
1.31
3.29
1.3
1.5
2.56
2.54
g/l
0.06
141
1191
190
1481
1.34
3.25
2.7
2.6
20.94
22.99
%
1.46
178
1388
154
1163
1.38
3.22
2.3
2.9
1.86
1.83
%
0.12
130
1055
32
164
1.98
3.22
1.3
1.8
0.63
0.89
g/l
0.70
21
131
179
1387
1.35
3.19
1.4
1.3
542.00
507.06
titre
0.09
40
309
15
55
2.75
3.16
1.1
1.5
1.72
1.25
nmol/l
—
8
38
117
851
1.42
3.05
2.3
2.5
5.12
7.53
ug/l
0.77
101
760
479
4226
1.24
3.03
2.2
2.0
1.46
1.38
mmol/l
1.10
407
3570
220
1770
1.31
3.01
3.4
3.5
0.81
0.82
mmol/l
0.90
203
1677
8
17
4.73
2.92
2.4
2.0
20.20
17.25
umol/l
—
8
17
9
22
4.12
2.88
1.1
1.1
—
—
—
0
0
22
102
2.18
2.88
4.1
4.0
—
—
—
0
0
118
874
1.39
2.79
1.6
1.4
—
—
—
0
0
312
2650
1.25
2.73
2.6
2.8
338.09
346.23
umol/l
0.71
265
2345
45
272
1.68
2.72
2.0
1.7
11517.50
13991.85
e6/l
0.29
32
193
48
754
0.62
2.72
3.5
3.8
—
—
—
0
0
40
238
1.71
2.57
1.4
1.4
13.07
8.21
u/l
0.94
32
190
60
396
1.55
2.57
1.4
1.2
0.28
1.25
u/ml
—
6
25
67
454
1.51
2.54
2.0
1.6
0.39
0.34
mg/l
0.27
39
226
384
4346
0.82
2.52
12.3
11.9
0.01
0.00
e9/l
0.43
323
3545
34
195
1.77
2.49
1.5
1.3
62.32
60.92
mmol/l
0.07
28
160
84
599
1.44
2.48
1.2
1.2
307.49
135.60
u/ml
1.81
32
242
22
109
2.04
2.47
3.8
2.5
—
—
—
0
0
965
9298
1.35
2.46
6.1
5.2
1.43
1.45
mmol/l
1.03
890
8630
463
4135
1.21
2.45
3.7
3.5
6.30
6.21
ph
0.95
238
2346
9
27
3.35
2.39
1.8
1.6
82.56
56.15
nmol/24h
—
9
27
24
125
1.94
2.37
8.0
2.4
—
—
—
0
0
125
961
1.34
2.36
2.6
2.2
408.56
374.29
nmol/l
0.96
117
905
968
9344
1.34
2.32
6.3
5.3
4.57
4.63
mmol/l
1.10
893
8722
20
98
2.06
2.32
1.9
1.3
8459.78
142642.21
e6/l
—
9
70
149
1178
1.31
2.32
1.4
1.4
—
—
—
0
0
22
112
1.98
2.31
1.6
1.6
66.33
61.94
%
0.25
15
79
102
765
1.37
2.27
1.1
1.2
—
—
—
0
0
14
60
2.35
2.22
2.1
1.9
—
—
—
0
0
19
93
2.06
2.22
1.3
1.3
0.50
0.40
g/l
0.35
12
65
19
93
2.06
2.22
1.3
1.3
6.24
7.53
g/l
0.74
12
67
19
93
2.06
2.22
1.3
1.3
2.68
2.79
g/l
0.06
13
66
68
480
1.44
2.15
2.5
2.4
—
—
—
0
0
45
293
1.56
2.09
1.4
1.4
204.29
278.14
ug/g
1.60
22
173
99
750
1.35
2.08
2.6
2.4
6.09
6.07
ph
0.06
64
515
169
1381
1.27
2.05
6.6
6.2
1.04
1.03
mmol/l
0.37
155
1281
57
806
0.69
2.00
3.2
4.1
1.24
1.23
mmol/l
0.23
47
703
63
446
1.44
1.98
1.5
2.0
—
—
—
0
0
734
7744
0.84
1.97
24.4
20.6
13.78
13.66
%
1.47
725
7651
170
1399
1.26
1.95
1.3
1.2
—
—
—
0
0
8
27
2.98
1.94
7.4
3.3
—
—
—
0
0
7
22
3.20
1.88
3.3
3.3
—
—
—
0
0
340
3015
1.19
1.84
6.7
6.4
—
—
—
0
0
157
1290
1.25
1.83
1.4
1.3
—
—
—
0
0
5
12
4.18
1.82
2.0
2.5
0.60
0.75
u/field
—
5
12
133
1074
1.27
1.79
4.4
3.5
7.37
7.38
ph
0.41
73
617
60
431
1.42
1.77
1.8
1.9
3.13
7.45
iu/ml
—
9
105
374
3357
1.17
1.74
4.1
3.3
45.65
33.70
u/l
0.37
353
3172
74
555
1.36
1.70
4.1
3.4
4.52
4.52
pmol/l
0.02
65
492
233
2019
1.20
1.62
1.8
1.7
453.97
34994503.34
pmol/l
2.13
186
1686
100
790
1.29
1.62
4.3
4.0
76.73
87.25
ng/l
0.97
82
700
20
113
1.78
1.61
1.1
1.4
21.91
27.62
ng/l
0.68
20
113
81
623
1.32
1.59
4.1
3.5
24.00
24.29
mmol/l
0.36
81
616
559
5201
1.15
1.58
4.1
3.9
0.07
0.32
estimate
0.39
61
1001
30
191
1.59
1.58
3.8
3.5
26.73
25.00
mg/l
0.09
22
126
62
458
1.38
1.58
1.8
2.0
1.70
1.54
g/l
0.67
54
410
349
3139
1.17
1.56
2.8
3.2
1093.18
1155.37
ng/l
0.18
295
2679
59
434
1.38
1.54
2.3
1.9
0.86
1.91
ug/l
0.81
52
390
8
33
2.43
1.54
7.4
2.8
—
—
—
0
0
22
131
1.69
1.50
1.7
2.3
428.75
4351.04
u/l
—
8
41
139
1160
1.23
1.43
2.5
2.8
8.28
8.50
umol/l
0.04
118
1043
17
95
1.80
1.43
1.2
1.3
—
—
—
0
0
33
221
1.51
1.42
6.4
1.9
—
—
—
0
0
31
205
1.53
1.41
2.9
3.4
0.76
0.87
nmol/l
0.70
23
171
548
5119
1.14
1.41
4.0
3.9
0.00
0.00
estimate
-0.00
73
1054
197
1705
1.19
1.40
1.3
1.3
13.41
10.79
u/ml
0.19
66
648
101
818
1.26
1.37
2.8
3.1
11.56
10.87
g/l
0.57
89
759
6
23
2.62
1.37
1.5
1.3
29.88
98.55
mu/l
—
6
18
123
1019
1.23
1.37
1.6
1.6
—
—
—
0
0
124
1030
1.23
1.35
4.2
3.5
1.38
1.87
mmol/l
0.67
112
886
12
221
0.54
1.34
2.8
3.7
—
—
—
0
0
10
47
2.14
1.34
1.0
3.9
675.50
1303.72
u/ml
—
10
47
52
387
1.36
1.30
2.3
2.8
—
—
—
0
0
128
1072
1.22
1.29
4.4
3.5
5.74
5.81
kpa
0.27
128
1041
12
217
0.55
1.27
1.1
1.2
—
—
—
0
0
8
35
2.30
1.27
3.7
1.5
—
—
—
0
0
9
44
2.05
1.27
1.2
1.2
—
—
—
0
0
46
338
1.38
1.25
1.5
1.6
16.20
11.47
u/ml
—
5
71
8
160
0.50
1.25
2.3
1.8
2.02
1.63
mmol/l
—
8
154
550
5168
1.13
1.24
4.0
3.9
18.66
4.85
estimate
0.33
71
1082
36
254
1.43
1.23
1.4
1.3
328.27
202.31
miu/ml
—
8
113
36
254
1.43
1.23
1.8
1.8
2.63
28.68
iu/l
0.54
12
95
29
196
1.49
1.22
9.3
2.6
—
—
—
0
0
12
214
0.56
1.22
3.3
3.1
6.52
7.53
mmol/l
0.83
12
209
467
4347
1.13
1.22
3.2
3.0
132.82
143.28
ug/l
0.39
421
4053
14
78
1.81
1.21
1.1
1.1
—
88.84
—
0
5
12
213
0.56
1.20
1.9
2.5
15.32
16.34
%
0.80
12
208
38
273
1.41
1.19
3.4
3.3
1.46
1.99
index
0.42
22
149
14
79
1.78
1.17
1.0
1.1
—
—
—
0
0
6
127
0.47
1.17
1.2
1.2
—
—
—
0
0
162
1402
1.18
1.17
2.0
1.8
—
—
—
0
0
36
258
1.41
1.15
1.2
1.1
—
—
—
0
0
35
250
1.41
1.14
1.8
3.2
32.66
33.90
umol/l
0.10
29
226
7
30
2.34
1.12
2.0
2.0
—
—
—
0
0
7
30
2.34
1.12
1.3
1.5
7.43
7.68
mmol/l
—
7
30
11
58
1.91
1.12
2.5
1.3
6.91
6.27
ug/l
0.20
11
51
5
21
2.39
1.09
1.0
1.8
—
—
—
0
0
127
1084
1.19
1.08
3.3
4.4
76.81
21.77
ug/l
0.45
102
894
20
300
0.66
1.04
21.1
10.7
—
—
—
0
0
22
146
1.52
1.03
1.1
1.1
2.60
1.90
u/ml
—
10
84
17
106
1.61
1.03
2.8
1.8
10.04
10.74
%
0.29
17
106
141
1223
1.18
1.01
1.8
1.6
—
—
—
0
0
7
131
0.53
0.99
1.1
2.6
29.86
32.69
pg
—
7
131
16
100
1.61
0.97
1.5
1.5
0.23
0.35
nmol/l
—
9
75
23
157
1.48
0.96
1.1
1.1
116.60
74.10
iu/ml
—
5
29
13
210
0.61
0.95
2.6
1.4
—
—
—
0
0
246
2232
1.13
0.95
1.6
1.7
1.25
1.24
mg/l
0.01
186
1731
15
93
1.62
0.94
3.1
3.7
17.56
12.13
index
—
9
63
79
655
1.22
0.93
1.8
1.8
1.39
1.43
g/l
0.07
71
609
13
79
1.65
0.88
1.8
1.9
1.75
1.96
u/field
—
8
45
6
30
2.01
0.87
1.2
1.4
—
—
—
0
0
35
265
1.33
0.85
6.4
2.0
—
—
—
0
0
13
203
0.64
0.85
2.0
1.3
—
—
—
0
0
119
1035
1.17
0.84
1.8
1.5
—
—
—
0
0
295
2726
1.11
0.84
3.2
3.0
0.00
0.04
—
5
54
18
261
0.68
0.83
3.3
2.9
1.55
1.55
mmol/l
0.01
18
255
6
115
0.52
0.83
3.3
1.4
—
—
—
0
0
12
73
1.65
0.81
1.0
1.1
—
—
—
0
0
14
89
1.58
0.81
1.0
1.1
294.44
284.92
mg/l
—
9
78
751
7737
0.90
0.81
27.9
21.4
333.37
332.53
g/l
1.72
744
7701
8
47
1.71
0.80
1.3
1.9
79.11
55.82
ug/l
—
8
47
18
122
1.48
0.80
1.6
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
19
131
1.46
0.78
1.1
1.6
—
—
—
0
0
19
131
1.46
0.78
1.1
1.6
—
—
—
0
0
19
131
1.46
0.78
1.1
1.6
—
—
—
0
0
19
131
1.46
0.78
1.1
1.6
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
17.00
—
0
5
77
651
1.20
0.77
2.5
2.5
16.13
19.90
au/ml
—
7
58
6
34
1.77
0.76
1.3
1.3
0.00
0.09
estimate
—
6
34
0
28
0.00
0.76
0.0
1.2
—
138.52
—
0
21
28
210
1.34
0.74
2.8
1.2
30.48
28.35
u/l
0.06
22
179
261
2817
0.90
0.74
3.5
3.3
0.34
0.45
e6/l
0.48
205
2083
15
219
0.68
0.73
2.4
2.7
89.99
89.74
%
0.07
15
212
9
55
1.64
0.73
1.1
1.4
166.89
152.38
nmol/l
—
9
55
305
3264
0.91
0.73
3.5
3.5
420.11
80.68
e6/l
0.43
248
2524
41
326
1.27
0.73
3.1
3.7
1.75
2.41
ratio
0.93
27
188
202
2204
0.90
0.70
5.7
5.1
—
—
—
0
0
5
26
1.93
0.70
1.2
1.1
142.80
324.87
pmol/l
—
5
16
191
2089
0.90
0.70
2.9
3.1
0.61
0.73
ug/l
2.13
117
1280
58
483
1.21
0.69
1.3
1.2
—
—
—
0
0
18
127
1.42
0.68
1.3
1.2
—
—
—
0
0
24
317
0.75
0.67
1.3
1.1
1.50
1.52
g/l
0.10
24
317
44
358
1.24
0.66
3.5
3.9
47.85
65.93
mg/l
0.48
38
304
44
358
1.24
0.66
3.5
3.9
33.27
50.32
mg/l
0.80
37
306
14
202
0.69
0.66
1.5
3.4
5.15
8.59
pmol/l
3.28
14
202
347
3674
0.92
0.65
3.9
4.1
57.18
114.17
e6/l
1.38
256
2638
7
44
1.59
0.65
3.1
2.0
38.54
40.06
g/l
—
7
44
12
178
0.67
0.65
3.6
3.4
3.82
4.27
e9/l
0.54
12
178
39
317
1.24
0.60
1.1
1.1
—
—
—
0
0
29
228
1.28
0.59
1.9
1.8
—
—
—
0
0
71
815
0.86
0.57
1.5
1.4
—
—
—
0
0
5
89
0.56
0.56
1.0
1.1
73.60
104.91
pmol/l
—
5
89
13
90
1.45
0.55
1.3
1.1
—
—
—
0
0
34
276
1.24
0.54
2.9
2.7
53.74
61.60
%
1.32
34
268
9
62
1.46
0.53
1.1
1.0
—
—
—
0
0
17
226
0.75
0.52
3.0
3.4
54.93
57.98
%
0.47
17
226
9
63
1.43
0.52
3.2
4.1
0.78
0.90
index
—
9
63
17
126
1.35
0.51
1.1
1.0
0.24
5.95
u/ml
—
5
62
200
1861
1.09
0.51
1.4
1.3
56.11
31.00
iu/ml
0.99
57
574
30
242
1.25
0.51
1.3
1.3
—
—
—
0
0
150
1628
0.91
0.50
3.2
3.2
2.37
2.12
e6/l
0.20
81
808
70
793
0.87
0.48
1.5
1.4
—
—
—
0
0
7
110
0.63
0.48
1.6
1.1
—
—
—
0
0
35
290
1.21
0.48
6.5
1.9
—
—
—
0
0
64
560
1.15
0.48
2.0
1.7
—
—
—
0
0
63
716
0.87
0.46
1.6
1.8
3.27
3.51
mmol/l
0.84
40
537
261
2757
0.93
0.46
3.5
3.3
0.02
0.04
estimate
0.22
56
841
44
375
1.18
0.46
1.3
2.4
10.82
10.70
g/l
0.06
34
341
35
292
1.21
0.45
6.8
1.9
—
—
—
0
0
35
292
1.21
0.45
6.5
1.9
—
—
—
0
0
361
3455
1.07
0.45
5.0
5.2
1.77
2.19
ug/l
1.26
321
3147
16
207
0.77
0.43
1.1
1.2
221.64
274.95
u/ml
0.43
11
121
6
94
0.64
0.42
1.5
2.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
1.70
—
0
15
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
6.33
—
0
16
0
16
0.00
0.41
0.0
2.2
—
53.38
—
0
6
8
59
1.36
0.41
2.7
2.3
3.41
2.19
ug/l
—
8
50
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
7
103
0.68
0.39
2.4
2.4
—
—
—
0
0
83
912
0.90
0.37
6.4
5.2
0.12
0.14
%
0.09
34
230
8
113
0.71
0.37
2.5
1.3
—
—
—
0
0
5
37
1.35
0.37
1.0
1.6
29.00
31.86
%
—
5
37
26
218
1.20
0.34
1.2
2.1
0.86
0.87
nmol/l
0.03
20
184
6
44
1.37
0.34
2.7
2.3
—
—
—
0
0
316
3042
1.05
0.33
4.8
4.3
7.40
7.40
ph
0.24
238
2223
6
46
1.31
0.33
1.2
1.2
6.17
9.35
mm/h
—
6
46
95
878
1.09
0.32
3.2
3.0
66.90
66.91
g/l
0.01
82
819
71
647
1.10
0.32
1.2
1.3
—
—
—
0
0
83
902
0.91
0.32
5.7
4.9
0.15
0.13
%
0.09
33
253
18
219
0.82
0.31
1.7
1.6
—
—
—
0
0
98
908
1.09
0.31
3.6
2.8
4.54
4.47
kpa
0.16
98
878
7
52
1.35
0.31
1.4
1.4
22.11
23.81
umol/l
—
7
44
14
111
1.26
0.30
1.1
1.0
3.21
2.09
u/ml
—
6
52
37
325
1.14
0.30
1.1
1.1
—
—
—
0
0
28
241
1.17
0.29
1.6
1.1
—
—
—
0
0
14
173
0.81
0.28
1.5
1.8
—
—
—
0
0
8
63
1.27
0.27
1.8
1.3
—
—
—
0
0
16
131
1.22
0.27
1.3
1.2
—
—
—
0
0
8
65
1.23
0.27
1.8
1.8
121.38
90.45
ng/l
—
8
65
15
122
1.23
0.27
1.4
1.1
—
—
—
0
0
33
291
1.14
0.26
4.2
1.8
—
—
—
0
0
11
86
1.28
0.26
1.2
1.3
—
—
—
0
0
25
288
0.86
0.25
1.2
1.3
—
—
—
0
0
10
127
0.79
0.25
2.9
2.6
0.28
1.20
g/24h
—
5
79
15
123
1.22
0.25
1.1
1.1
0.29
1.90
u/ml
—
5
46
25
217
1.16
0.24
3.2
3.7
425.71
1370.81
u/ml
0.38
25
206
15
124
1.21
0.24
1.1
1.3
—
—
nmol/l
—
0
0
211
2030
1.05
0.24
3.0
3.0
2.45
2.45
mmol/l
0.58
189
1840
28
246
1.14
0.24
1.7
2.4
70.86
84.71
ug/min
0.17
16
141
28
246
1.14
0.24
1.9
2.1
121.84
129.30
g/l
0.82
19
196
12
97
1.24
0.23
1.2
1.2
—
—
—
0
0
36
400
0.90
0.23
1.6
1.7
—
—
—
0
0
7
94
0.74
0.22
1.7
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
42.55
—
0
11
0
11
0.00
0.21
0.0
1.0
—
18.72
—
0
11
16
188
0.85
0.21
1.1
1.1
—
—
—
0
0
78
731
1.07
0.21
2.9
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
61.24
—
0
5
8
101
0.79
0.21
1.4
1.3
—
—
—
0
0
76
713
1.07
0.20
1.3
1.5
—
—
—
0
0
16
187
0.85
0.20
1.3
1.4
—
10.17
—
0
6
6
48
1.25
0.20
1.8
1.3
29.33
30.70
umol/l
—
6
43
22
193
1.14
0.19
1.0
1.1
—
—
—
0
0
6
51
1.18
0.19
2.2
1.6
—
—
—
0
0
85
899
0.94
0.19
5.2
4.7
0.58
0.58
%
0.01
36
273
20
228
0.87
0.19
2.5
4.7
—
—
—
0
0
171
1772
0.96
0.18
3.1
3.0
0.82
1.04
e6/l
0.67
103
954
111
1059
1.05
0.18
1.7
1.6
—
—
—
0
0
12
100
1.20
0.18
2.0
1.9
—
—
—
0
0
296
2889
1.03
0.18
4.3
4.0
0.00
0.01
estimate
1.15
60
988
7
63
1.11
0.17
1.0
1.0
—
—
—
0
0
186
1917
0.96
0.16
2.8
3.0
529.92
532.67
mosm/kgh2o
0.05
165
1689
8
72
1.11
0.16
1.1
1.1
—
—
—
0
0
396
3893
1.03
0.15
4.0
3.8
1.81
0.02
estimate
0.51
57
876
14
160
0.87
0.14
2.6
2.7
—
—
—
0
0
10
84
1.19
0.14
8.4
5.2
92.20
28.28
u/ml
—
5
30
12
103
1.17
0.13
1.0
1.2
—
—
—
0
0
8
100
0.80
0.13
1.3
1.3
—
—
—
0
0
99
952
1.04
0.13
3.0
2.4
12.38
13.63
nmol/l
0.73
83
871
91
946
0.96
0.12
5.6
4.9
0.71
0.95
%
0.86
41
298
67
639
1.05
0.12
10.7
11.1
24.50
24.42
mmol/l
0.07
67
632
12
104
1.16
0.12
1.6
1.4
—
—
—
0
0
269
2642
1.02
0.11
1.3
1.4
—
—
—
0
0
10
86
1.16
0.11
4.4
3.2
228.52
15.06
mg/l
—
5
64
95
918
1.04
0.11
9.8
9.7
—
—
—
0
0
11
96
1.15
0.10
1.2
1.1
—
—
—
0
0
5
45
1.11
0.10
1.4
1.0
1570.20
1538.29
miu/ml
—
5
45
12
106
1.13
0.09
1.5
1.6
—
—
—
0
0
16
145
1.11
0.09
1.3
1.4
0.53
13.25
nmol/l
0.50
16
135
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
37
390
0.95
0.09
1.5
1.2
—
—
—
0
0
23
215
1.07
0.07
1.2
1.2
—
—
—
0
0
38
363
1.05
0.07
2.5
3.9
203.53
300.66
mg/l
0.89
15
164
7
84
0.83
0.07
1.0
1.1
—
—
—
0
0
49
503
0.97
0.04
1.1
1.1
—
—
—
0
0
10
109
0.92
0.04
2.9
2.3
—
—
—
0
0
13
121
1.08
0.03
1.1
1.0
1.01
1.79
u/ml
—
5
57
100
990
1.01
0.02
2.3
2.5
65.79
39.65
u/l
0.46
85
832
14
147
0.95
0.01
4.9
2.6
—
—
—
0
0
46
468
0.98
0.01
2.1
3.6
1.02
1.02
ratio
0.58
41
442
12
126
0.95
0.00
1.2
2.1
—
2512.00
—
0
5
12
124
0.97
0.00
1.1
1.4
—
—
—
0
0
11
112
0.98
0.00
2.1
4.9
5.28
7.22
mmol/l
—
6
93
12
119
1.01
0.00
1.1
1.1
—
—
—
0
0
16
159
1.01
0.00
1.4
1.1
—
—
—
0
0
226
2261
1.00
0.00
2.7
2.8
4.96
5.31
e6/l
0.22
208
2081
14
137
1.02
0.00
1.7
1.4
36.15
32.30
g/l
1.11
14
124
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
28.41
—
0
7
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
0.12
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
384.83
—
0
6
5
54
0.93
-0.00
1.2
1.3
7.53
7.40
ph
—
5
38
10
100
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
402.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
16
160
1.00
-0.00
1.4
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
245.82
—
0
6
5
52
0.96
-0.00
16.0
7.4
1.38
295.28
ug/l
—
5
39

Mortality – FinRegistry

Association

Association between endpoint K11_ORAL_LEUCOPLACIA_INCLAVO and mortality.

Females

Parameter HR [95% CI] p-value
K11_ORAL_LEUCOPLACIA_INCLAVO 1.138 [0.99, 1.31] 0.067
Birth year 0.989 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 415 out of 2412 females with K11_ORAL_LEUCOPLACIA_INCLAVO died.

Males

Parameter HR [95% CI] p-value
K11_ORAL_LEUCOPLACIA_INCLAVO 1.208 [1.05, 1.39] 0.008
Birth year 0.987 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 419 out of 2342 males with K11_ORAL_LEUCOPLACIA_INCLAVO died.

Mortality risk

Mortality risk for people of age

years, who have K11_ORAL_LEUCOPLACIA_INCLAVO.

N-year risk Females Males
1 0.085% 0.16%
5 0.554% 1.325%
10 1.446% 3.321%
15 2.758% 6.967%
20 4.837% 11.545%

Relationships between endpoints

Index endpoint: K11_ORAL_LEUCOPLACIA_INCLAVO – Oral leukoplakia, including avohilmo

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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