Oher contracture of tendon (sheath)

M13_TENDONCONTRACT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M67.1 Cause of death: ICD-10 — M67.1 2 out of 7 registries used, show all original rules.	141
4. Check minimum number of events None	141
5. Include endpoints None	141
6. Filter based on genotype QC (FinnGen only)	129

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M67
Name in latin: Alia contractura tendinis et vaginae tendinis

NAME	M13_TENDONCONTRACT
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M671
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M671
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Oher contracture of tendon (sheath) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	895	394	498
Only index persons	856	381	475
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	54.47	52.79	55.66
Only index persons	53.77	52.82	54.53

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	129	65	64
Unadjusted period prevalence (%)	0.03	0.02	0.03
Median age at first event (years)	55.85	53.47	58.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
131: Matched controls
1310

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M67.1

ICD-10 Finland

Other contracture of tendon (sheath)

+∞

189.2

131

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

183.1

39.2

NDM10

NOMESCO Finland

Palmar fasciotomy of hand

403.9

32.3

G56.0

ICD-10 Finland

Carpal tunnel syndrome

6.9

19.8

M75.1

ICD-10 Finland

Rotator cuff syndrome

4.8

14.9

120

NDM40

NOMESCO Finland

Discission of sheath of tendon of wrist or hand

168.0

14.8

ACC51

NOMESCO Finland

Release of median nerve

9.9

11.9

M65.3

ICD-10 Finland

Trigger finger

14.7

11.0

M67.4

ICD-10 Finland

Ganglion

12.1

10.7

NDM20

NOMESCO Finland

Excision of synovial ganglion of wrist or hand

119.2

10.6

M19.0

ICD-10 Finland

Primary arthrosis of other joints

5.4

10.2

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

4.1

10.0

N02AX02

ATC

tramadol; systemic, rectal

3.2

9.6

326

ZXA05

NOMESCO Finland

Left side

3.2

8.2

162

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

23.8

8.2

L12

ICPC

Hand/finger symptom/complaint

3.5

7.8

106

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

2.8

6.9

198

M25.5

ICD-10 Finland

Pain in joint

2.8

6.7

208

NHL68

NOMESCO Finland

Tenodesis, shortening or lengthening of tendon of foot

73.3

6.5

M02AA07

ATC

piroxicam; topical

2.6

6.5

262

R4120

NOMESCO Finland

Occupational therapy

6.4

NBT60

NOMESCO Finland

Forcible manipulation of humeroscapular joint

+∞

6.3

7286A

ICD-9 Finland

Disorders of muscle, ligament and fascia, Contracture of palmar fascia

+∞

6.3

TNX10

NOMESCO Finland

Arthrocentesis, unspecified region, unspecified region

6.4

6.0

L03

ICPC

Low back symptom/complaint

2.7

6.0

182

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

145

2.82

5.77

1.2

1.36

19.21

u/ml

1.51

(3019198) Lymphocytes [#/volume] in Blood

557

2.42

5.48

7.0

5.9

1.91

1.81

e9/l

0.48

504

(3001604) Monocytes [#/volume] in Blood

552

2.37

5.32

7.1

5.9

0.58

0.59

e9/l

0.14

486

(3006315) Basophils [#/volume] in Blood

554

2.36

5.24

7.1

5.9

0.04

e9/l

0.18

487

(3024561) Albumin [Mass/volume] in Serum or Plasma

479

2.25

4.92

5.2

4.6

34.71

35.53

g/l

0.55

461

(3002030) Lymphocytes/Leukocytes in Blood

509

2.24

4.83

6.9

6.0

28.36

26.68

0.62

487

(3013115) Eosinophils [#/volume] in Blood

569

2.25

4.72

7.3

6.1

0.22

0.18

e9/l

0.84

508

(42870588) Differential panel, method unspecified - Blood

356

2.20

4.58

6.4

5.5

—

(3022096) Basophils/Leukocytes in Blood

495

2.14

4.35

7.2

5.9

0.76

0.67

0.76

468

(3006504) Eosinophils/Leukocytes in Blood

498

2.12

4.25

7.2

5.9

3.12

2.78

0.54

472

(3019069) Monocytes/Leukocytes in Blood

502

2.09

4.11

7.2

6.0

9.27

8.94

0.38

477

(3044290) Cell count panel - Cerebral spinal fluid

7.66

3.92

1.0

1.5

—

(3032080) INR in Blood by Coagulation assay

495

1.95

3.45

11.6

12.1

1.23

1.22

inr

0.08

404

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

167

2.21

3.43

1.3

1.2

22.40

53.22

iu/ml

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

221

2.09

3.40

1.6

1.5

0.69

1.46

mg/l

1.72

180

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

477

1.88

3.16

2.2

2.0

96.94

94.89

pmol/l

0.13

256

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

337

1.90

3.06

4.6

2.2

53.09

70.96

u/l

0.75

309

(3019550) Sodium [Moles/volume] in Serum or Plasma

125

1123

3.47

2.97

24.9

17.2

139.84

139.80

mmol/l

0.06

125

1096

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

496

1.83

2.89

3.0

2.7

—

estimate

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

615

1.83

2.80

3.2

2.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

739

1.89

2.75

5.7

4.1

—

1.91

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

102

837

1.99

2.72

4.9

3.7

14.87

14.79

pmol/l

0.10

754

(3013650) Neutrophils [#/volume] in Blood by Automated count

614

1.78

2.58

9.1

10.1

3.79

4.27

e9/l

1.44

549

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

188

1.93

2.47

1.7

1.9

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

786

1.83

2.40

5.9

4.0

13.16

11.86

mm/h

0.38

727

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

126

1160

3.26

2.34

16.4

11.5

26.04

27.02

u/l

0.31

126

1126

(3007853) Bacteria identified in Skin by Aerobe culture

104

2.09

2.14

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.33

2.14

1.6

3.2

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

122

1113

2.40

2.07

6.4

5.9

2.61

2.70

mmol/l

0.64

115

1036

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

232

1.76

2.06

1.3

1.2

1.00

1.25

u/ml

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

116

1030

2.10

1.99

7.7

6.4

41.22

39.64

mmol/mol

0.95

111

968

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

3.46

1.99

2.6

1.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

120

1080

2.32

1.98

22.5

14.4

25.39

25.30

mg/l

0.01

106

859

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

115

1022

2.03

1.91

6.3

4.5

1.99

mu/l

0.02

105

927

(40761511) CBC panel - Blood by Automated count

123

1130

2.45

1.87

20.7

13.4

—

(4024509) Urine culture

2.46

1.83

1.6

1.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.35

1.80

9.1

13.0

24.09

24.90

mmol/l

0.38

(3019309) Folate [Moles/volume] in Red Blood Cells

166

1.79

1.80

1.7

1.6

1271.35

1162.19

nmol/l

0.21

130

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

137

1.82

1.69

1.7

1.9

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

125

1169

2.51

1.64

28.1

19.4

80.51

79.10

umol/l

0.12

125

1152

(3021788) Differential panel - Synovial fluid

3.67

1.63

2.2

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

533

1.53

1.58

9.4

7.7

1.21

mmol/l

0.03

464

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

119

1086

2.05

1.58

5.4

5.1

1.45

1.46

mmol/l

0.14

112

1003

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.93

1.56

2.8

3.6

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

482

1.50

1.45

8.7

7.1

1.21

mmol/l

0.03

449

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

115

1046

1.81

1.42

4.7

4.3

1.16

1.29

mmol/l

1.77

109

966

(3021960) Folate [Moles/volume] in Serum or Plasma

308

1.54

1.41

1.6

18.04

19.04

nmol/l

0.19

259

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

145

1.71

1.41

1.7

1.8

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.68

1.38

1.2

—

(3009508) Creatinine [Moles/volume] in Urine

394

1.48

1.33

4.3

3.4

7.40

8.00

mmol/l

0.61

337

(3012516) Albumin [Mass/volume] in Urine

376

1.48

1.32

4.6

3.5

28.66

69.81

mg/l

1.63

250

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

2.57

1.32

1.2

1.3

0.00

g/l

—

(3021589) Normoblasts [#/volume] in Blood

500

1.46

1.30

13.4

10.9

0.00

0.01

e9/l

0.53

413

(1616796) Gas panel - Central venous blood

2.85

1.29

8.6

3.4

—

(3023368) Bacteria identified in Blood by Culture

296

1.51

1.28

6.4

4.3

—

(3048689) Calprotectin [Mass/mass] in Stool

109

1.76

1.27

1.9

2.4

53.77

191.99

ug/g

1.82

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.24

1.24

2.0

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

362

1.47

1.23

3.2

3.5

2.35

mmol/l

0.01

332

(3017732) Neutrophils [#/volume] in Blood

118

1.71

1.23

2.3

2.6

3.22

7.05

e9/l

1.19

102

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.02

1.21

1.6

1.4

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.08

1.20

1.2

1.8

2.11

4.28

mg/l

—

(40760888) Immunoglobulin light chains.free panel - Serum

2.56

1.16

1.6

7.5

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.90

1.13

2.8

3.2

23.09

23.99

mmol/l

0.37

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

197

1.54

1.12

3.6

2.6

2.22

1.08

e6/l

0.76

111

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

122

1.65

1.10

13.8

7.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

114

1.67

1.09

1.4

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

251

1.48

1.09

7.0

5.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.00

1.09

1.3

1.2

—

(3018418) pH of Serum or Plasma

333

1.43

1.08

6.5

4.6

7.40

0.03

252

(3020682) Albumin/Creatinine [Ratio] in Urine

389

1.41

1.08

5.3

4.2

5.40

11.89

mg/mmol

1.12

251

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.18

1.07

4.7

2.8

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

261

1.47

1.07

2.4

2.0

2.10

3.02

mg/l

2.59

229

(3005322) IgE [Units/volume] in Serum or Plasma

1.91

1.06

1.2

769.55

512.83

u/ml

0.15

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.12

1.04

1.1

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

263

1.45

1.03

2.5

2.4

—

(3015736) pH of Urine

478

1.38

1.02

5.1

3.1

6.32

6.20

0.40

275

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.90

1.01

2.7

2.2

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.00

0.98

2.0

1.7

—

(3012544) pH of Venous blood

126

1.59

0.98

3.8

3.1

7.40

7.38

0.61

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

206

1.46

0.91

4.3

3.9

40.14

446.20

ng/l

1.37

168

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

2.12

0.90

1.0

1.3

—

3.05

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.12

0.90

2.0

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.12

0.90

1.0

1.3

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

2.12

0.90

1.0

1.3

—

4.26

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.83

0.86

1.5

1.4

—

(3009261) Glucose [Presence] in Urine by Test strip

596

1.33

0.86

5.6

3.5

0.00

estimate

—

108

(36660697) Celiac disease serology panel - Serum

1.67

0.85

1.3

1.2

—

(40768443) Skin Pathology biopsy report

1.75

0.82

1.9

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.75

0.78

1.2

1.7

—

(3037522) Nuclear Ab [Titer] in Serum

142

1.48

0.78

1.2

1.3

342.86

492.31

titre

—

(40761535) Cells panel - Urine sediment

1.66

0.78

3.9

3.8

—

(3035350) Ketones [Presence] in Urine by Test strip

592

1.31

0.78

5.7

3.4

0.00

estimate

—

117

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.22

0.77

2.0

1.2

—

(3008898) HLA-B27 [Presence]

2.12

0.75

1.4

1.0

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.12

0.75

1.2

1.0

—

2.04

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.89

0.75

1.4

4.6

29.74

34.19

mg/l

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.89

0.75

1.4

4.5

35.79

86.43

mg/l

—

(3019060) Gas panel - Arterial blood

1.67

0.74

4.7

3.6

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

101

1.55

0.74

2.0

1.5

—

(40758558) Short blood count panel - Blood

325

1.33

0.74

4.9

6.9

—

(3000850) Epithelial cells [#/volume] in Urine

243

1.36

0.72

4.1

2.5

4.85

7.44

e6/l

0.35

222

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.96

0.71

6.4

8.0

—

166.50

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

1.96

0.71

1.2

1.7

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.88

0.69

1.0

—

(3010421) pH of Blood

1.88

0.69

11.2

3.7

7.42

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

423

1.29

0.69

4.5

3.9

22.40

33.63

ng/l

1.00

300

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

1.57

0.69

2.1

2.5

75.67

60.16

ml/min/173m2

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

103

1.52

0.68

6.7

8.9

1.42

1.44

mmol/l

0.02

103

(3030467) Casts [#/volume] in Urine by Automated count

311

1.31

0.66

5.0

2.8

0.18

0.48

e6/l

1.33

220

(3023420) DNA double strand Ab [Units/volume] in Serum

1.62

0.66

1.0

1.5

—

4.26

—

(3002582) Erythrocytes [#/volume] in Urine

369

1.29

0.64

4.9

2.9

79.88

41.58

e6/l

0.37

279

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.67

0.63

1.4

1.1

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.60

0.62

1.5

1.3

—

41.00

—

(3025941) Bacteria identified in Stool by Culture

1.57

0.61

1.1

1.3

—

(3014051) Protein [Presence] in Urine by Test strip

315

1.29

0.60

4.3

2.7

—

0.00

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

334

1.28

0.60

5.4

4.8

21.24

21.40

0.03

172

(3044640) Blood type and Crossmatch panel - Blood

353

1.28

0.60

2.6

2.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

586

1.25

0.60

5.4

3.5

0.00

estimate

-0.00

116

(3042936) Bacteria identified in Isolate by Culture

159

1.38

0.60

2.6

2.0

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

250

1.31

0.60

3.4

3.2

0.69

0.94

ug/l

0.93

164

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.60

0.0

3.5

—

57.77

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

113

1073

1.39

0.58

19.1

14.4

80.62

79.75

ml/min/173m2

0.17

106

993

(4034850) Laboratory test

1.75

0.58

24.2

8.6

—

(3026008) Bacteria identified in Urine by Culture

307

1.29

0.58

5.6

2.7

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

108

1.44

0.56

3.3

2.5

0.05

0.21

e6/l

2.33

103

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

404

1.25

0.56

5.2

3.0

—

(3018095) Leukocytes [#/volume] in Urine

424

1.25

0.55

5.2

3.4

266.05

99.94

e6/l

0.43

299

(3013512) EKG study

376

1.26

0.55

4.8

3.7

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

101

1.43

0.52

1.3

1.4

—

(3000492) Spirometry study

102

1.42

0.50

1.5

1.6

—

(3026782) Osmolality of Urine

192

1.31

0.49

6.3

3.1

600.93

554.16

mosm/kgh2o

0.64

165

(40768804) Tissue Pathology biopsy report

432

1.21

0.45

1.9

2.1

—

(40768797) Stomach Pathology biopsy report

131

1.34

0.45

1.2

—

(3022313) Gas panel - Capillary blood

1.39

0.45

6.1

3.7

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.39

0.45

1.7

3.0

51.00

36.70

u/l

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

414

1.21

0.44

6.4

5.7

1.86

3.66

ug/l

1.18

369

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.64

0.43

1.2

1.7

—

(3000494) Fungus identified in Specimen by Culture

141

1.32

0.43

1.4

—

(3020891) Body temperature

1.40

0.42

4.3

4.1

37.01

36.98

°c

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.38

0.42

1.5

1.6

—

(44806420) Estimation of glomerular filtration rate

0.00

0.41

0.0

1.7

—

(40768795) Lymph node Pathology biopsy report

0.00

0.41

0.0

1.1

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.35

0.41

1.4

2.0

1.19

1.30

g/l

—

(3019977) pH of Arterial blood

133

1.32

0.41

8.8

8.3

7.43

7.42

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.41

0.0

1.3

—

(3019150) Specific gravity of Urine by Refractometry

255

1.23

0.39

6.0

3.5

1.02

kg/l

0.15

168

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

1.40

0.38

1.0

1.3

0.71

0.92

g/l

—

(3022145) Colonoscopy Study observation

117

1.32

0.37

1.5

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.49

0.36

1.2

1.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

451

1.18

0.35

5.8

3.5

0.00

0.03

estimate

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

175

1.24

0.32

4.4

2.8

2.85

2.10

e6/l

0.22

(3017143) Hepatitis C virus Ab [Presence] in Serum

129

1.27

0.32

1.8

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

157

1.25

0.32

1.7

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

223

1.21

0.31

1.8

1.7

578947785.53

407.19

pmol/l

0.48

200

(3001122) Ferritin [Mass/volume] in Serum or Plasma

504

1.16

0.31

3.3

2.6

119.41

114.06

ug/l

0.08

472

(3007164) IgA [Mass/volume] in Serum or Plasma

226

1.19

0.27

1.5

1.4

2.43

2.36

g/l

0.11

142

(3014576) Chloride [Moles/volume] in Serum or Plasma

160

1.22

0.27

5.5

7.0

105.21

104.78

mmol/l

0.15

160

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

1.33

0.23

1.0

1.8

44.60

38.92

nmol/l

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.33

0.23

1.4

1.8

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.27

0.23

1.8

277.27

391.95

nmol/l

1.44

(1761868) Lipid panel - Serum or Plasma

464

1.13

0.22

3.0

3.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.26

0.22

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.21

0.0

1.0

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.1

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.21

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.2

—

1.17

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.2

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.20

0.0

1.1

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.20

0.0

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.24

0.17

1.5

1.6

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.12

0.16

2.1

2.6

0.59

0.61

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.12

0.16

11.4

10.7

25.00

24.49

mmol/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.77

0.15

1.0

2.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.21

0.14

2.8

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.21

0.14

1.3

2.0

—

(3000991) Gas panel - Venous blood

103

1.18

0.14

9.0

9.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

180

0.87

0.14

1.3

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.82

0.14

1.0

2.3

—

(3002179) Metamyelocytes/Leukocytes in Blood

1.17

0.12

4.9

4.4

0.40

0.44

—

(3029937) Albumin [Presence] in Urine by Test strip

329

1.09

0.12

5.5

3.6

0.00

0.02

estimate

—

108

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.09

0.09

1.0

2.5

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.09

0.07

2.1

2.7

0.98

1.09

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.07

0.07

12.9

10.9

92.70

92.75

—

(40761536) Microorganisms panel - Urine sediment

0.87

0.07

7.3

3.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

179

1.07

0.05

1.7

2.1

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

470

0.97

0.03

1.7

1.9

1.19

1.34

mmol/l

1.07

386

(3002256) Pathology report gross observation

143

1.06

0.01

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

329

1.00

0.00

5.5

3.0

0.00

estimate

—

(4035726) Immunohistochemistry procedure

108

1.02

0.00

1.4

—

(21494755) Public health laboratory ask at order entry panel

115

1.05

0.00

1.3

1.5

—

(1002224) Polysomnography panel

1.00

0.00

1.0

1.1

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

31.62

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.2

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.8

—

10.28

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.3

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

1.7

—

82.98

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3048518) aPTT.lupus sensitive actual/normal (normalized LA screen)

0.00

-0.00

0.0

1.2

—

1.10

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.92

-0.00

1.2

2.5

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.1

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

160

1.00

-0.00

1.5

1.6

—

(3036035) von Willebrand factor (vWf) Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

-0.00

0.0

1.0

—

176.60

—

(3020650) Glucose [Presence] in Urine

0.00

-0.00

0.0

1.2

—

0.00

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

5.3

—

5.80

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

68.86

—

(3044007) Cell count panel - Peritoneal fluid

0.00

-0.00

0.0

1.2

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.7

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(40758292) HTLV I+II Ab panel - Serum

0.00

-0.00

0.0

1.4

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.3

—

55.00

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.6

—

0.71

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.0

—

(3024263) Appearance of Synovial fluid

0.00

-0.00

0.0

1.2

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.2

—

9.98

—

(3003694) ABO and Rh group [Type] in Blood

300

1.00

-0.00

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

1.6

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.2

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.8

—

7.55

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.8

—

4.49

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.2

—

(3022621) pH of Urine by Test strip

0.99

-0.00

2.0

6.36

6.30

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_TENDONCONTRACT and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
M13_TENDONCONTRACT	0.751 [0.57, 0.99]	0.041
Birth year	0.991 [0.98, 1.0]	0.042

During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 451 males with M13_TENDONCONTRACT died.

Mortality risk

Mortality risk for people of age

years, who have M13_TENDONCONTRACT.

N-year risk	Females	Males
1	No data	0.162%
5	No data	0.972%
10	No data	2.63%
15	No data	4.932%
20	No data	8.201%

Relationships between endpoints

↥

Index endpoint: M13_TENDONCONTRACT – Oher contracture of tendon (sheath)

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Oher contracture of tendon (sheath)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints