No definition available.
Acquired clawhand, clubhand, clawfoot and clubfoot
M13_CLAWCLUBHANDFOOT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
226 |
4. Check minimum number of eventsNone |
226 |
5. Include endpointsNone |
226 |
6. Filter based on genotype QC (FinnGen only) |
206 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M21
- Name in latin
- Deformitas [acquisita] manus sive pedis, typus talipes
Similar endpoints
↥List of similar endpoints to
Acquired clawhand, clubhand, clawfoot and clubfoot
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1250 | 679 | 569 |
| Only index persons | 1221 | 666 | 555 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.01 | 49.30 | 46.45 |
| Only index persons | 47.95 | 49.50 | 46.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 206 | 123 | 83 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 51.66 | 50.63 | 53.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 211
- Matched controls
- 2110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
+∞
303.2
211
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
39.2
120.7
81
33
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
26.8
83.9
63
33
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
18.5
75.5
69
54
M19.0
ICD-10 Finland
Primary arthrosis of other joints
35.2
74.0
49
18
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
22.5
66.7
53
31
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
+∞
60.4
55
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
+∞
52.3
48
*
L16
ICPC
Ankle symptom/complaint
8.2
43.6
74
131
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
500.7
42.8
41
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
15.2
41.2
39
31
WX320
NOMESCO Finland
Spinalanesthesy
6.8
38.8
81
176
M25.5
ICD-10 Finland
Pain in joint
6.0
37.1
99
269
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
148.7
36.0
37
*
L17
ICPC
Foot/toe symptom/complaint
5.7
35.6
113
355
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
12.6
34.0
36
34
NH3EA
NOMESCO Finland
Feet X-ray examination with load
194.4
32.7
33
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.3
31.9
68
148
N03AX12
ATC
[U] gabapentin; oral
6.4
31.5
66
141
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
11.2
31.5
36
38
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
10.9
31.0
36
39
B01AB05
ATC
enoxaparin; parenteral
5.2
30.4
97
299
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
+∞
29.9
28
*
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
335.7
29.6
29
*
WX725
NOMESCO Finland
Noninvasive ventilation
9.1
29.5
40
53
WX720
NOMESCO Finland
Own respiration
11.3
29.3
33
34
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
167.1
28.4
29
*
TPH04
NOMESCO Finland
Cathetrisation of vein
5.1
28.3
82
232
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
31.7
28.2
37
14
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
12.3
27.5
29
27
WX702
NOMESCO Finland
Supraglottic ventilation device
8.7
27.2
38
52
SPAT1229
SPAT
Assessment of need for aid
9.2
25.9
34
43
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
+∞
25.5
24
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
+∞
25.5
24
*
B01AB10
ATC
tinzaparin; parenteral
6.6
25.1
46
85
M77.4
ICD-10 Finland
Metatarsalgia
8.1
25.1
37
54
NHG22
NOMESCO Finland
Fusion of subtalar joint
+∞
23.4
22
*
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
94.1
23.2
25
*
WX704
NOMESCO Finland
Intubation
6.2
22.6
44
86
TQW40
NOMESCO Finland
Remowal of suture of skin
7.8
22.4
34
51
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
20.7
21.7
32
18
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
7.8
21.5
32
47
Q66.0
ICD-10 Finland
Talipes equinovarus
232.0
21.0
21
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
5.2
20.9
51
122
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
53.8
20.6
24
5
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.8
20.4
116
515
M16.1
ICD-10 Finland
Other primary coxarthrosis
32.7
20.2
26
9
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
20.1
19
*
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
61.0
19.3
22
*
Z01.8
ICD-10 Finland
Other specified special examinations
3.9
19.3
78
274
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
19.0
18
*
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
42.7
19.0
23
6
Q66.7
ICD-10 Finland
Pes cavus
109.9
18.9
20
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.2
18.5
35
66
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
32.0
17.8
23
8
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
195.8
17.8
18
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.6
17.4
84
329
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
16.9
16
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
16.9
16
*
M19.2
ICD-10 Finland
Other secondary arthrosis
+∞
16.9
16
*
N02AJ06
ATC
codeine and paracetamol; systemic
3.3
16.6
112
536
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.7
16.6
72
262
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.8
16.3
42
104
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
14.6
16.2
27
21
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
+∞
15.8
15
*
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
92.1
15.8
17
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
7.5
15.2
23
34
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
61.3
15.0
17
*
SPAT1153
SPAT
Removal of sutures
3.3
15.0
80
329
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.4
14.2
40
106
X59
ICD-10 Finland
Exposure to unspecified factor
3.6
13.8
57
198
L15
ICPC
Knee symptom/complaint
3.5
13.8
60
216
N03AX16
ATC
[U] pregabalin
3.4
13.6
60
218
M79.6
ICD-10 Finland
Pain in limb
2.9
13.4
113
594
N02AX02
ATC
tramadol; systemic, rectal
3.0
13.4
100
493
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.3
13.3
29
62
NHL30
NOMESCO Finland
Suture or reinsertion of tendon of foot
30.6
13.2
17
6
L28
ICPC
Limited function/disability (L)
3.8
13.0
47
149
M20.1
ICD-10 Finland
Hallux valgus (acquired)
15.6
12.6
20
14
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.9
12.4
41
122
NH1AD
NOMESCO Finland
Ankle and foot CT
19.5
12.3
18
10
WX400
NOMESCO Finland
Inhalation anesthesy
5.6
12.1
24
47
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
49.7
12.0
14
*
ZXA00
NOMESCO Finland
Right side
3.2
12.0
59
227
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.4
12.0
25
51
M01AH05
ATC
etoricoxib; oral
2.9
11.8
149
948
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
126.6
11.5
12
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.9
11.5
38
113
L08
ICPC
Shoulder symptom/complaint
3.1
11.5
59
233
M01AH01
ATC
celecoxib; oral
3.6
11.2
42
136
B01AF01
ATC
rivaroxaban; oral
5.0
11.0
25
55
X58
ICD-10 Finland
Exposure to other specified factors
3.4
10.8
44
150
S93.4
ICD-10 Finland
Sprain and strain of ankle
3.5
10.8
42
139
UKC02
NOMESCO Finland
Cystoscopy
3.6
10.8
41
134
L13
ICPC
Hip symptom/complaint
3.4
10.7
45
157
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
5.6
10.6
21
41
NHG20
NOMESCO Finland
Fusion of talocrural joint
+∞
10.5
10
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
+∞
10.5
10
*
Z3229
NOMESCO Finland
Other healthcare associate professional
4.8
10.4
25
58
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
21.3
9.9
14
7
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.5
9.9
100
554
L03
ICPC
Low back symptom/complaint
2.6
9.8
76
370
N06AX21
ATC
duloxetine; oral
3.5
9.6
36
116
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
18.6
9.5
14
8
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
104.5
9.5
10
*
R5110, ,
SPAT
4.5
9.5
24
58
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
+∞
9.4
9
*
WX111
NOMESCO Finland
Local infiltration anesthesia
+∞
9.4
9
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.9
9.4
52
212
SAA02
NOMESCO Finland
Basic examination of mouth
2.9
9.4
165
1174
A02BC05
ATC
esomeprazole; systemic
2.5
9.3
95
525
NHE15
NOMESCO Finland
Suture or reinsertion of ligament of ankle
38.5
9.1
11
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.7
9.0
62
283
ZXD20
NOMESCO Finland
Day surgery
3.5
9.0
33
105
WX110
NOMESCO Finland
Infiltration anesthesia
3.0
8.9
173
1275
A46
ICD-10 Finland
Erysipelas
3.2
8.9
40
144
M03BX01
ATC
baclofen; systemic
14.9
8.8
14
10
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
52.2
8.8
10
*
M21.6
ICD-10 Finland
Other acquired deformities of ankle and foot
52.2
8.8
10
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
13.5
8.5
14
11
75400
ICD-8 Finland
Clubfoot (congenital), Pes equino-varus adductus
93.6
8.5
9
*
N02BF01
ATC
gabapentin; oral
3.6
8.5
30
93
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
10.1
8.4
16
17
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
11.4
8.4
15
14
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
8.4
8
*
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
+∞
8.4
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
8.4
67
328
WX002
NOMESCO Finland
Sedation and analgesia
3.0
8.3
41
156
M01AE03
ATC
ketoprofen; systemic, rectal
2.4
8.3
82
443
S92.3
ICD-10 Finland
Fracture of metatarsal bone
6.8
8.2
20
32
WZA00
NOMESCO Finland
Concise certificate
4.6
8.1
20
47
A02BC03
ATC
lansoprazole; oral
2.5
8.1
66
325
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
8.1
27
80
L84
ICD-10 Finland
Corns and callosities
9.0
8.0
16
19
S15
ICPC
Foreign body in skin
4.6
7.9
19
44
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
15.8
7.8
12
8
WX213
NOMESCO Finland
Lower leg blockade
46.7
7.8
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
7.7
37
138
SPAT1301
SPAT
No procedures
2.4
7.7
70
361
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
4.0
7.7
23
63
L29
ICPC
Musculoskeletal sympt/complt other
3.6
7.7
27
83
N02BE01
ATC
paracetamol; systemic, rectal
3.9
7.7
194
1570
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.9
7.7
24
68
NH3AA, ,
SPAT
4.0
7.6
22
59
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.3
7.5
20
50
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.9
7.5
40
159
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
82.9
7.5
8
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
8.9
7.5
15
18
M19.8
ICD-10 Finland
Other specified arthrosis
11.5
7.4
13
12
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
7.3
7
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
7.3
7
*
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.8
7.3
17
38
ZXA05
NOMESCO Finland
Left side
2.6
7.3
48
213
S18
ICPC
Laceration/cut
2.2
7.2
101
622
ZA7.0
ICD-10 Finland
Ankle and foot
20.9
7.2
10
5
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
20.9
7.2
10
5
M54.5
ICD-10 Finland
Low back pain
2.2
7.2
83
473
UJF32
NOMESCO Finland
Coloscopy
2.5
7.2
57
276
L90
ICPC
Osteoarthrosis of knee
10.6
7.1
13
13
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
6.8
7.1
17
27
SPAT1234
SPAT
Support of social functional capacity
6.2
7.1
18
31
W00
ICD-10 Finland
Fall on same level involving ice and snow
3.1
7.0
32
116
W19
ICD-10 Finland
Unspecified fall
3.5
7.0
25
78
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
6.9
56
273
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.2
6.9
29
100
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
7.6
6.8
15
21
L18
ICPC
Muscle pain
5.9
6.8
18
33
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
3.7
6.8
22
64
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
23.4
6.7
9
*
SAA01
NOMESCO Finland
Simple examination of mouth
2.5
6.7
169
1302
M70.6
ICD-10 Finland
Trochanteric bursitis
3.0
6.7
31
113
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.6
6.6
23
70
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
10.5
6.6
12
12
S93.2
ICD-10 Finland
Rupture of ligaments at ankle and foot level
10.5
6.6
12
12
WX402
NOMESCO Finland
General anaesthesia
2.4
6.6
57
286
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.2
6.6
18
46
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
7.8
6.5
14
19
ACC51
NOMESCO Finland
Release of median nerve
3.8
6.5
20
56
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
71.9
6.5
7
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
71.9
6.5
7
*
NHL50
NOMESCO Finland
Tenolysis or tenosynovectomy of foot
71.9
6.5
7
*
M24.2
ICD-10 Finland
Disorder of ligament
71.9
6.5
7
*
L88
ICPC
Rheumatoid/seropositive arthritis
14.9
6.5
10
7
A07EC01
ATC
sulfasalazine; oral, rectal
6.3
6.4
16
27
L12
ICPC
Hand/finger symptom/complaint
2.5
6.4
44
198
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.9
6.4
33
128
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.5
6.4
11
10
S97
ICPC
Chronic ulcer skin
3.9
6.4
19
52
SPAT1262
SPAT
Handing over of treatment supplies
2.5
6.4
44
199
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
+∞
6.3
6
*
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
+∞
6.3
6
*
WX210
NOMESCO Finland
Plexus blockade of nervus ichiadicus
27.6
6.3
8
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
27.6
6.3
8
*
M01AX17
ATC
nimesulide; oral
2.4
6.2
47
221
M01AX05
ATC
glucosamine; oral
3.4
6.2
23
73
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
6.2
27
95
SGA05
NOMESCO Finland
Opening and preparing the root canals, extremely complicated And time consuming
3.7
6.2
20
58
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
6.4
6.1
15
25
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
10.5
6.1
11
11
G47.3
ICD-10 Finland
Sleep apnoea
2.3
6.1
59
310
M01AH02
ATC
rofecoxib; oral
3.2
6.1
25
85
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
157
952
3.54
15.08
5.8
5.4
6.57
6.63
mmol/l
0.11
144
895
129
730
2.97
13.32
3.2
2.7
—
—
estimate
—
0
0
116
676
2.59
10.46
7.7
5.2
35.67
36.55
g/l
1.01
109
648
52
210
2.96
9.57
1.6
1.6
1089.58
1241.08
nmol/l
0.51
38
166
124
778
2.44
9.10
10.5
8.2
1.22
1.21
mmol/l
0.21
110
685
96
557
2.33
8.19
3.1
2.6
52.21
71.78
u/l
1.03
90
522
172
1293
2.79
8.01
10.4
7.9
79.01
76.81
u/l
0.34
167
1232
55
254
2.58
7.70
1.4
1.1
26.01
1.61
u/ml
0.77
19
119
70
371
2.33
7.21
1.9
1.6
0.65
1.15
mg/l
1.71
58
286
14
16
9.28
7.17
4.4
1.7
10.71
11.60
mmol/l
0.37
14
16
107
681
2.16
6.97
7.9
7.3
1.22
1.22
mmol/l
0.34
98
638
164
1239
2.45
6.96
6.2
3.5
12.25
10.00
mm/h
1.15
155
1163
25
80
3.41
6.69
5.4
3.7
1.24
1.54
mmol/l
0.17
17
66
96
595
2.13
6.61
3.6
3.2
31.05
33.93
ng/l
0.12
67
380
128
893
2.10
6.34
7.5
7.1
9.52
10.98
umol/l
1.60
120
859
18
50
3.84
5.90
3.1
2.0
24.41
24.92
mmol/l
0.21
18
50
42
193
2.47
5.84
6.0
4.0
31.53
30.72
%
0.19
30
138
67
382
2.10
5.57
2.9
3.3
1280.88
970.59
ng/l
0.27
57
320
65
377
2.05
5.11
4.0
2.6
321.76
335.27
umol/l
0.48
58
346
166
1332
2.15
5.02
4.5
3.2
43.98
42.34
u/l
0.12
159
1278
47
242
2.21
5.01
2.4
2.0
—
—
—
0
0
54
297
2.10
4.87
3.3
3.8
0.79
0.82
mmol/l
1.36
49
289
83
537
1.90
4.70
5.0
4.1
28.21
10.73
mg/mmol
0.57
49
343
51
278
2.10
4.69
1.5
1.2
18.30
14.04
iu/ml
0.28
16
85
11
18
6.38
4.67
1.4
1.4
—
—
—
0
0
193
1669
2.83
4.59
6.5
5.0
1.79
1.89
mu/l
0.79
185
1569
170
1399
2.11
4.47
5.1
4.2
14.74
14.58
pmol/l
0.38
156
1315
14
41
3.59
4.26
4.1
1.7
8.01
7.95
kpa
0.06
14
41
198
1752
3.11
4.17
22.8
12.8
18.71
24.54
mg/l
2.43
180
1346
69
437
1.86
4.08
1.4
1.3
1.19
2.02
u/ml
0.39
16
144
53
318
1.89
3.66
1.6
1.7
466.89
67857598.45
pmol/l
0.77
45
280
95
684
1.71
3.53
2.5
1.9
107.28
95.94
pmol/l
1.26
50
376
33
169
2.13
3.53
8.8
12.7
2.22
1.33
mmol/l
0.57
24
140
67
440
1.77
3.44
1.7
1.5
18.01
19.50
nmol/l
0.45
59
381
33
171
2.10
3.43
9.3
12.6
5.08
5.18
kpa
0.28
28
166
103
764
1.68
3.39
3.2
2.4
77.73
74.23
nmol/l
0.54
95
705
117
901
1.67
3.31
4.0
3.3
0.00
0.00
estimate
-0.00
22
176
91
657
1.68
3.29
5.9
3.1
28.20
29.50
u/l
0.26
84
629
40
226
1.95
3.29
3.0
2.2
2.25
2.32
g/l
0.40
35
211
60
389
1.76
3.20
2.8
1.9
2.44
2.84
mg/l
0.79
53
333
60
397
1.71
2.95
3.7
3.3
1.02
1.02
kg/l
0.14
47
268
50
314
1.78
2.95
3.7
4.1
9.06
545.92
ng/l
2.35
36
219
15
58
2.71
2.94
2.2
2.3
—
—
—
0
0
7
13
5.53
2.89
1.1
1.0
—
—
—
0
0
75
531
1.64
2.85
3.2
2.6
0.00
0.01
estimate
0.50
19
140
10
28
3.70
2.82
1.3
1.3
—
—
—
0
0
115
908
1.59
2.75
4.0
3.3
0.00
0.00
estimate
-0.00
21
163
189
1699
2.08
2.75
8.0
5.6
40.37
38.66
mmol/mol
1.30
181
1612
36
210
1.86
2.69
3.5
8.0
103.67
104.41
mmol/l
0.35
36
210
15
62
2.53
2.60
1.0
1.0
—
9.99
—
0
9
10
32
3.23
2.47
5.9
1.8
11.39
6.34
pmol/l
—
10
32
30
172
1.87
2.36
2.8
1.8
—
—
—
0
0
30
174
1.84
2.28
2.6
1.8
—
—
—
0
0
190
1737
1.94
2.23
5.4
4.5
5.87
5.85
mmol/l
0.09
177
1628
111
897
1.50
2.22
4.0
3.2
0.00
0.00
estimate
-0.00
23
175
23
124
1.96
2.17
1.4
1.4
—
—
—
0
0
10
36
2.86
2.17
1.9
1.6
—
—
—
0
0
12
50
2.48
2.06
1.2
1.2
—
—
—
0
0
6
15
4.08
2.05
1.2
1.3
1.83
2.13
mmol/l
—
6
15
9
33
2.80
1.95
2.6
1.5
136.44
130.92
g/l
—
9
25
13
58
2.32
1.95
2.0
1.9
—
—
—
0
0
13
58
2.32
1.95
1.7
1.9
37.69
39.17
nmol/l
0.08
13
58
90
711
1.46
1.95
3.9
3.1
0.00
0.00
estimate
-0.00
20
151
8
28
2.93
1.88
2.1
1.8
12.88
12.99
%
—
8
28
64
478
1.49
1.82
4.5
3.4
0.00
0.01
estimate
0.50
19
166
120
1010
1.44
1.81
9.3
10.6
4.21
4.06
e9/l
0.34
107
875
7
23
3.11
1.81
1.6
1.6
—
—
—
0
0
143
1244
1.46
1.80
3.2
3.3
—
—
—
0
0
6
18
3.40
1.76
2.0
2.0
—
—
—
0
0
97
789
1.42
1.75
2.3
1.9
1.39
1.38
mmol/l
0.01
81
665
8
30
2.73
1.74
1.7
1.5
—
—
—
0
0
8
32
2.56
1.61
1.0
1.3
—
67.38
—
0
6
7
26
2.75
1.59
1.1
1.1
—
—
—
0
0
5
129
0.37
1.55
3.0
2.0
—
—
—
0
0
197
1860
1.89
1.51
6.6
5.2
2.68
2.83
mmol/l
1.67
187
1762
70
550
1.41
1.49
2.2
3.8
2.34
2.37
mmol/l
0.94
63
511
7
28
2.55
1.46
1.7
1.5
—
—
—
0
0
5
16
3.17
1.44
1.4
1.3
120.40
117.25
pmol/l
—
5
16
195
1841
1.78
1.42
6.0
4.7
4.56
4.75
mmol/l
2.01
185
1750
10
47
2.18
1.36
3.1
2.0
199.80
235.62
pmol/l
—
10
42
10
47
2.18
1.36
1.0
1.0
—
3.00
—
0
8
104
883
1.35
1.35
3.7
2.9
160.10
109.88
ug/l
0.67
98
841
6
24
2.54
1.31
1.7
1.3
—
—
—
0
0
18
107
1.75
1.30
2.1
1.7
—
—
—
0
0
184
1733
1.48
1.10
16.3
12.2
83.93
86.11
ml/min/173m2
0.66
173
1598
47
365
1.37
1.06
2.5
2.4
—
—
—
0
0
7
34
2.09
1.04
1.7
1.5
—
—
—
0
0
9
47
1.95
1.03
1.0
1.2
—
—
—
0
0
12
68
1.81
1.03
2.5
3.3
43.16
50.12
%
0.32
12
68
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
6
27
2.26
0.94
1.2
1.1
—
2.42
—
0
7
27
194
1.45
0.94
5.1
3.0
5.20
6.71
umol/l
0.50
22
172
13
79
1.69
0.90
1.4
1.7
—
—
—
0
0
8
43
1.89
0.88
1.7
1.7
—
—
—
0
0
13
80
1.67
0.87
4.2
4.1
24.98
24.06
mmol/l
0.49
13
80
8
45
1.81
0.85
1.6
1.7
—
—
—
0
0
6
31
1.96
0.85
1.3
1.7
130.32
47.81
ug/l
—
6
31
8
47
1.73
0.81
3.5
2.8
—
—
—
0
0
184
1754
1.38
0.81
4.9
4.0
1.33
1.30
mmol/l
0.21
175
1649
5
99
0.49
0.80
4.8
11.6
1.46
1.47
%
—
5
99
5
99
0.49
0.80
4.8
11.5
0.58
0.64
%
—
5
99
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
50
410
1.29
0.78
4.0
4.0
18.57
20.99
%
0.64
22
179
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
9
56
1.63
0.73
1.7
1.7
—
—
—
0
0
7
39
1.82
0.73
1.0
1.4
—
—
—
0
0
21
282
0.72
0.71
2.4
2.5
1.02
0.97
e6/l
0.04
11
135
19
258
0.71
0.69
2.5
2.4
—
—
—
0
0
22
163
1.39
0.67
6.5
5.8
—
—
—
0
0
5
28
1.80
0.66
1.0
1.2
—
—
—
0
0
13
88
1.51
0.62
1.4
1.4
—
—
—
0
0
190
1837
1.34
0.59
6.1
4.6
1.47
1.45
mmol/l
0.21
181
1734
0
23
0.00
0.58
0.0
1.9
—
15.60
—
0
23
10
148
0.66
0.57
2.2
2.1
—
—
—
0
0
44
372
1.23
0.55
1.8
1.5
—
—
—
0
0
7
45
1.57
0.49
1.3
1.2
—
—
—
0
0
7
46
1.54
0.49
1.1
1.5
—
—
—
0
0
7
47
1.51
0.48
1.0
4.2
1.10
1.68
ratio
—
7
27
21
262
0.78
0.45
2.8
2.6
2.75
2.21
e6/l
0.12
12
114
5
32
1.58
0.42
1.6
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
4.7
—
970.33
—
0
15
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
7
102
0.68
0.40
1.9
2.0
7.59
2.69
mg/l
—
7
75
5
34
1.48
0.40
1.0
1.2
—
—
—
0
0
5
34
1.48
0.40
1.0
1.2
—
—
—
0
0
5
34
1.48
0.40
2.4
4.8
—
5020.40
—
0
5
19
151
1.28
0.40
1.2
1.2
219.29
163.09
u/ml
—
7
67
14
107
1.33
0.38
2.1
2.1
27.99
52.90
u/ml
0.55
14
102
17
134
1.29
0.38
2.2
1.3
55.98
302.89
u/ml
1.22
17
122
5
37
1.36
0.37
2.0
1.9
—
—
—
0
0
6
43
1.41
0.35
1.8
2.0
—
—
—
0
0
20
232
0.85
0.24
2.2
2.3
—
—
—
0
0
5
39
1.29
0.23
1.2
1.2
4.00
22.87
e6/l
—
5
31
14
116
1.22
0.22
6.4
3.1
1.23
1.23
mmol/l
0.07
14
99
5
40
1.26
0.22
1.2
1.3
1178.20
93.85
e6/l
—
5
34
0
11
0.00
0.21
0.0
1.0
—
532.83
—
0
6
0
10
0.00
0.21
0.0
1.0
—
8.40
—
0
10
0
10
0.00
0.21
0.0
3.2
—
1.80
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
69.81
—
0
12
5
66
0.75
0.17
1.8
1.5
—
—
—
0
0
6
79
0.75
0.16
1.2
2.8
2.35
1.24
%
—
6
79
9
81
1.12
0.15
1.7
1.8
—
—
—
0
0
7
86
0.81
0.15
1.6
1.6
226.14
348.90
mu/l
—
7
80
18
160
1.14
0.14
4.5
4.7
8.14
10.31
ug/l
0.14
12
136
12
105
1.15
0.11
1.2
1.0
—
—
—
0
0
43
453
0.94
0.11
3.9
2.7
0.32
0.41
e6/l
0.24
36
313
35
333
1.06
0.08
1.5
1.6
—
—
—
0
0
8
75
1.07
0.07
1.4
1.7
—
—
—
0
0
30
315
0.94
0.07
3.1
2.6
0.73
0.78
ug/l
0.09
15
178
9
102
0.88
0.06
1.0
1.2
1.67
1.55
g/l
—
9
102
16
148
1.09
0.06
3.1
2.9
—
—
—
0
0
10
105
0.95
0.00
1.5
1.2
0.92
0.89
g/l
—
10
105
0
8
0.00
0.00
0.0
5.3
—
20.45
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.96
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
16.69
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.7
1543.47
950.21
mu/l
—
9
82
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_CLAWCLUBHANDFOOT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have M13_CLAWCLUBHANDFOOT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: M13_CLAWCLUBHANDFOOT – Acquired clawhand, clubhand, clawfoot and clubfoot
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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