Portal vein thrombosis

I9_PVT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I81
  • Hospital discharge: ICD-9 452
  • Hospital discharge: ICD-8 452
  • Cause of death: ICD-10 I81
  • Cause of death: ICD-9 452
  • Cause of death: ICD-8 452

2 out of 7 registries used, show all original rules.

685

4. Check minimum number of events

None

685

5. Include endpoints

None

685

6. Filter based on genotype QC (FinnGen only)

606

Control definitions (FinnGen only)

Control exclude
I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I80-I89
Name in latin
Thrombosis venae portae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3823 1578 2210
Only index persons 3061 1272 1789
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.06
Only index persons 0.06 0.05 0.07
Median age at first event (years)
Whole population 62.20 62.36 62.10
Only index persons 61.19 60.50 61.68

-FinnGen-

Key figures

All Female Male
Number of individuals 606 262 344
Unadjusted period prevalence (%) 0.13 0.09 0.16
Median age at first event (years) 62.92 61.78 63.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
630
Matched controls
6300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I81
ICD-10 Finland
Portal vein thrombosis
+∞
307.7
606
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
1462.1
126.6
119
*
B01AB05
ATC
enoxaparin; parenteral
6.6
124.2
389
1234
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.3
120.0
234
473
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
28.0
116.7
81
33
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
8.1
116.3
191
321
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
22.3
114.1
87
45
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
29.7
112.0
76
29
JN3AD
NOMESCO Finland
Abdominal CT examination
6.9
111.5
229
484
R18
ICD-10 Finland
Ascites
19.9
102.5
82
47
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.3
101.4
182
333
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
18.0
89.5
75
47
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.0
89.5
347
1238
B01AA03
ATC
warfarin; systemic
5.5
89.1
240
636
K83.0
ICD-10 Finland
Cholangitis
25.1
74.0
53
23
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
31.7
71.3
47
16
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
31.7
71.3
47
16
B01AB10
ATC
tinzaparin; parenteral
5.5
69.8
165
383
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
15.5
64.7
58
41
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
635.2
59.7
58
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
21.0
58.6
45
23
UJK02
NOMESCO Finland
ERCP
11.3
55.2
60
58
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
16.8
55.1
47
30
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
84.4
55.1
61
8
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
11.5
54.0
58
55
K83.1
ICD-10 Finland
Obstruction of bile duct
15.8
53.3
47
32
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
19.9
52.2
41
22
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.1
51.7
124
287
C03DA01
ATC
spironolactone; oral
4.3
50.9
160
459
Z51.5
ICD-10 Finland
Palliative care
4.9
50.0
129
317
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.7
49.8
102
205
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.4
49.7
316
1444
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
+∞
48.6
46
*
A05AA02
ATC
ursodeoxycholic acid; oral
18.8
48.5
39
22
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.5
48.1
55
57
B01AB04
ATC
dalteparin; parenteral
7.1
48.0
77
121
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
45.8
148
431
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.2
45.8
64
86
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
14.5
44.6
41
30
C03CA01
ATC
furosemide; systemic
3.2
44.6
284
1280
K92.1
ICD-10 Finland
Melaena
5.9
44.4
87
167
N02AA05
ATC
oxycodone; systemic
3.5
43.8
201
741
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
15.3
43.7
39
27
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
9.9
43.6
52
57
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
9.7
43.0
52
58
K86.1
ICD-10 Finland
Other chronic pancreatitis
17.3
43.0
36
22
130
Kela drug reimbursment
Malignant tumour
4.3
41.8
125
342
K92.0
ICD-10 Finland
Haematemesis
9.6
41.2
50
56
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
10.4
38.7
44
45
JN4AD
NOMESCO Finland
Body CT examination
3.7
38.0
144
465
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
37.8
222
938
A06AD11
ATC
lactulose; oral
3.5
37.3
155
531
R50.9
ICD-10 Finland
Fever, unspecified
3.5
36.8
159
558
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.3
36.6
65
113
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
11.8
36.5
38
34
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
6.7
35.9
60
98
JAH00
NOMESCO Finland
Laparotomy
6.9
35.2
57
90
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.2
34.8
174
666
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
9.0
34.8
44
52
C07AG02
ATC
carvedilol; oral
4.8
34.2
85
200
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
34.2
178
697
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
40.8
33.8
42
11
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.2
33.2
51
76
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
95.4
33.1
36
*
A10AB05
ATC
insulin aspart; parenteral
4.3
33.0
94
246
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
32.3
133
450
WW500
NOMESCO Finland
Blood transfusion
5.7
32.2
63
120
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
32.0
388
2341
UJF32
NOMESCO Finland
Coloscopy
2.8
31.3
230
1081
JN4BD
NOMESCO Finland
Extensive body CT
3.6
30.2
116
374
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
12.6
30.1
30
25
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
+∞
29.4
28
*
PHD99
NOMESCO Finland
Resection of other vein
305.4
29.0
29
*
J01MA12
ATC
levofloxacin; systemic
2.9
28.5
173
730
A10AE04
ATC
insulin glargine; parenteral
3.5
28.4
109
351
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
11.2
28.0
30
28
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
10.2
27.9
32
33
A03FA01
ATC
metoclopramide; systemic, rectal
2.7
27.1
192
876
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
9.4
27.0
33
37
127
Kela drug reimbursment
Transplant complication
9.3
26.1
32
36
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
29.9
25.6
34
12
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
6.5
24.9
42
69
J01MA02
ATC
ciprofloxacin; systemic
2.4
24.8
295
1700
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
6.2
24.6
43
73
A02BC02
ATC
pantoprazole; systemic
2.7
24.6
487
3513
ZXD05
NOMESCO Finland
Urgent procedure
2.4
24.2
234
1227
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.6
23.6
46
87
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
48.7
23.5
28
6
Z94.4
ICD-10 Finland
Liver transplant status
56.3
23.2
27
5
B01AF02
ATC
apixaban; oral
2.9
23.0
124
486
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.8
22.7
32
43
UJF30
NOMESCO Finland
Ileoscopy through colon
3.2
22.2
100
353
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
6.6
22.0
36
57
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.2
21.9
47
97
N02AX02
ATC
tramadol; systemic, rectal
2.2
21.7
328
2055
JJC00
NOMESCO Finland
Allogenic transplantation of liver
119.2
21.7
23
*
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
18.2
21.5
33
19
WX892
NOMESCO Finland
Monitored bed care
3.5
21.2
81
258
A41.9
ICD-10 Finland
Sepsis, unspecified
5.0
20.9
46
97
R10.0
ICD-10 Finland
Acute abdomen
5.6
20.9
41
78
K86.3
ICD-10 Finland
Pseudocyst of pancreas
31.3
20.7
27
9
C07AA05
ATC
propranolol; systemic
2.5
20.5
160
753
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.4
20.4
53
128
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
24.3
20.1
28
12
ZX120
NOMESCO Finland
Intravenous
3.1
20.0
90
317
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
76.0
19.8
22
*
H02AB02
ATC
dexamethasone; systemic
2.8
19.3
109
435
K76.9
ICD-10 Finland
Liver disease, unspecified
16.5
19.0
30
19
L01BC06
ATC
capecitabine; oral
4.4
19.0
49
118
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
18.9
134
600
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
18.8
18
*
K76.6
ICD-10 Finland
Portal hypertension
+∞
18.8
18
*
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
+∞
18.8
18
*
A04AA02
ATC
granisetron; systemic, transdermal
3.4
18.8
71
224
L04AA06
ATC
mycophenolic acid; systemic
6.7
18.5
30
47
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
18.5
149
708
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.8
18.4
58
162
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.3
18.3
38
76
103
Kela drug reimbursment
Diabetes, insulin-treated
2.2
18.0
218
1229
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.0
18.0
53
141
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
17.8
17
*
PHD76
NOMESCO Finland
Resection of long saphenous vein
+∞
17.8
17
*
45299
ICD-8 Finland
Portal vein thrombosis
+∞
17.8
17
*
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
4.2
17.8
49
124
K81.0
ICD-10 Finland
Acute cholecystitis
6.0
17.7
32
56
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
17.6
102
412
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.2
17.4
74
251
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
21.6
17.4
25
12
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.4
17.2
64
200
L01XX05
ATC
hydroxycarbamide; oral
7.1
17.1
26
38
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
26.4
17.0
23
9
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
22.6
17.0
24
11
WX002
NOMESCO Finland
Sedation and analgesia
2.3
16.6
149
739
JN4CD
NOMESCO Finland
Very extensive body CT
4.2
16.6
46
117
K94
ICPC
Phlebitis/thrombophlebitis
20.7
16.5
24
12
UJD02
NOMESCO Finland
Gastroscopy
3.8
16.5
52
145
K85
ICD-10 Finland
Acute pancreatitis
6.3
16.5
28
46
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
16.3
191
1056
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.2
16.2
28
47
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
15.9
195
1096
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.8
15.8
36
78
WZC30
NOMESCO Finland
Teaching
2.3
15.8
138
676
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
17.8
15.7
24
14
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.9
15.6
47
127
Z3231
NOMESCO Finland
Registered nurse
2.1
15.5
195
1105
R4110
NOMESCO Finland
Physiotherapy
2.1
15.5
205
1184
D68.8
ICD-10 Finland
Other specified coagulation defects
20.7
15.2
22
11
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
58.1
14.8
17
*
Z2221
NOMESCO Finland
Medical doctor
2.1
14.8
187
1058
WX402
NOMESCO Finland
General anaesthesia
2.1
14.7
169
922
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.8
14.7
27
48
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
14.5
88
363
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
6.2
14.4
25
42
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.5
14.3
100
441
A04AA01
ATC
ondansetron; systemic, rectal
2.9
14.3
74
281
R4190
NOMESCO Finland
Nutritional therapy
3.9
14.1
43
117
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
14.1
90
380
A46
ICD-10 Finland
Erysipelas
2.4
14.0
108
498
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
13.1
14.0
24
19
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.8
13.9
44
123
JFB00
NOMESCO Finland
Partial resection of small intestine
6.4
13.8
23
37
4520A
ICD-9 Finland
Portal vein thrombosis[THROMBOSIS VENAE PORTAE]
+∞
13.6
13
*
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
143.0
13.5
14
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.4
13.4
50
156
XW000
NOMESCO Finland
Bone marrow biopsy
3.6
13.4
46
136
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
11.8
13.4
24
21
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
13.4
246
1579
D45
ICD-10 Finland
Polycythaemia vera
10.8
13.3
25
24
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
10.0
13.3
26
27
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
14.2
13.3
22
16
UJF92
NOMESCO Finland
Capsular endoscopy
5.9
13.3
24
42
AA1AD
NOMESCO Finland
CT of head and brain
2.0
13.3
208
1264
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
41.0
13.2
16
*
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.9
13.2
29
61
L04AD02
ATC
tacrolimus; systemic
12.5
13.2
23
19
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
17.2
13.1
20
12
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
51.1
12.9
15
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
12.9
65
243
WX882
NOMESCO Finland
High dependency care
4.4
12.9
33
79
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
12.8
62
226
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.2
12.8
35
88
A07AA11
ATC
rifaximin; oral
32.8
12.6
16
5
P01AB01
ATC
metronidazole; oral, rectal
1.9
12.6
258
1706
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.9
12.6
61
223
I86.4
ICD-10 Finland
Gastric varices
+∞
12.5
12
*
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
12.5
12
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
132.5
12.5
13
*
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
132.5
12.5
13
*
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.7
12.5
29
64
Z3226
NOMESCO Finland
Physiotherapist
2.2
12.5
128
665
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.4
12.3
94
431
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
12.3
122
625
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
12.3
185
1105
A41.8
ICD-10 Finland
Other specified sepsis
4.9
12.2
27
57
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.3
12.2
32
78
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
12.1
125
651
TK800
NOMESCO Finland
Hemodialysis
5.0
12.0
26
54
JAH01
NOMESCO Finland
Laparoscopy
3.5
11.7
41
123
D97
ICPC
Liver disease NOS
30.7
11.7
15
5
L04AX01
ATC
azathioprine; systemic
3.8
11.7
36
99
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
66.2
11.6
13
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
66.2
11.6
13
*
ZXE00
NOMESCO Finland
One hour or less
1.8
11.6
245
1625
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.3
11.6
22
22
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
11.6
40
119
SPAT1262
SPAT
Handing over of treatment supplies
2.1
11.5
128
685
WPB10
NOMESCO Finland
Making a convalescent care decision
20.5
11.2
16
8
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
3.5
11.1
39
117
SPAT1255
SPAT
Intravenous administration of medicine
2.9
11.0
53
193
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.2
11.0
44
144
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
44.1
11.0
13
*
J01DB01
ATC
cefalexin; oral
2.0
10.9
511
4279
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
18.2
10.8
16
9
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
28.6
10.8
14
5
UJK12
NOMESCO Finland
Peroral cholangioscopy
61.1
10.7
12
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
10.6
37
111
T90
ICPC
Diabetes non-insulin dependent
1.9
10.5
178
1097
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
+∞
10.4
10
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
10.4
57
223
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
9.0
10.3
21
24
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.7
10.2
32
89
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
13.4
10.2
17
13
K29.6
ICD-10 Finland
Other gastritis
8.1
10.2
22
28
K72.9
ICD-10 Finland
Hepatic failure, unspecified
14.9
10.0
16
11
198
Kela drug reimbursment
Sorafenib
26.5
9.8
13
5
A10AE05
ATC
insulin detemir; parenteral
2.9
9.8
47
171
D01
ICPC
Abdominal pain/cramps general
2.3
9.7
82
391
ZX112
NOMESCO Finland
Subcutaneous
4.4
9.7
24
56
K65.0
ICD-10 Finland
Acute peritonitis
9.3
9.6
19
21
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.6
99
513
R60.9
ICD-10 Finland
Oedema, unspecified
2.9
9.5
44
157
J01FF01
ATC
clindamycin; systemic
1.8
9.5
174
1095
TJA10
NOMESCO Finland
Laparocentesis
30.5
9.4
12
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
9.4
93
473
JMA10
NOMESCO Finland
Transabdominal total splenectomy
12.6
9.4
16
13
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
22.1
9.4
13
6
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.9
9.3
17
16
K99
ICPC
Cardiovascular disease other
4.3
9.2
24
58
H02AB09
ATC
hydrocortisone; systemic
4.3
9.2
24
58
A10AC01
ATC
insulin (human); parenteral
2.5
9.2
58
243
A02BC01
ATC
omeprazole; systemic
1.8
9.2
177
1129
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
11.7
9.1
16
14
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
9.1
65
289
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.3
9.1
35
112
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.1
9.0
38
128
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
18.9
9.0
13
7
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
8.1
8.9
19
24
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
4.6
8.9
21
47
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.2
8.9
81
399
T89
ICPC
Diabetes insulin dependent
3.1
8.8
37
125
D02
ICPC
Abdominal pain epigastric
2.7
8.7
46
176
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
8.7
36
120
JKA20
NOMESCO Finland
Cholecystectomy
3.8
8.7
26
70
L04AD01
ATC
ciclosporin; systemic
4.5
8.7
21
48
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
8.6
179
1163
JLC30
NOMESCO Finland
Pancreatoduodenectomy
16.6
8.6
13
8
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
8.0
8.4
18
23
TPH00
NOMESCO Finland
Phlebotomy
13.0
8.4
14
11
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
+∞
8.3
8
*
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
+∞
8.3
8
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.1
8.3
35
118
K85.8
ICD-10 Finland
Other acute pancreatitis
9.6
8.3
16
17
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.3
222
1544
S97
ICPC
Chronic ulcer skin
2.6
8.2
50
206
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
7.7
8.2
18
24
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.5
8.2
53
225
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
8.2
29
88
R60.0
ICD-10 Finland
Localized oedema
2.1
8.1
82
420
Z2446
NOMESCO Finland
Social worker
2.5
8.1
50
207
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
11.9
8.1
14
12
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
11.9
8.1
14
12
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
11.9
8.1
14
12
J81
ICD-10 Finland
Pulmonary oedema
17.4
8.1
12
7
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
33.8
8.1
10
*
K75.0
ICD-10 Finland
Abscess of liver
22.3
8.0
11
5
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
22.3
8.0
11
5
A10BA02
ATC
metformin; oral
1.7
8.0
196
1330
WX872
NOMESCO Finland
Intensive care
2.7
7.9
43
167
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
7.9
97
533
E13
ICD-10 Finland
Other specified diabetes mellitus
13.2
7.9
13
10
A02BC05
ATC
esomeprazole; systemic
1.6
7.9
255
1855
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.0
7.8
22
57
N03AX16
ATC
[U] pregabalin
1.8
7.7
147
928
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
15.3
7.7
12
8
A02BC03
ATC
lansoprazole; oral
1.7
7.7
180
1204
K29
ICPC
Cardiovascular sympt/complt other
3.1
7.7
31
102
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
7.6
126
764
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
25.3
7.6
10
*
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
25.3
7.6
10
*
N05CF01
ATC
zopiclone; oral
1.7
7.6
203
1406
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
7.6
37
136
K29.7
ICD-10 Finland
Gastritis, unspecified
3.1
7.6
31
103
K51.5
ICD-10 Finland
Left sided colitis
3.8
7.5
23
63
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
7.5
95
529
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
7.4
48
204
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
9.5
7.3
14
15
I85
ICD-10 Finland
Oesophageal varices
+∞
7.3
7
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.3
224
1603
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.6
7.2
41
163
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
20.3
7.1
10
5
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
20.3
7.1
10
5
K55.8
ICD-10 Finland
Other vascular disorders of intestine
20.3
7.1
10
5
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
7.1
200
1399
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.4
7.1
48
208
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.7
7.1
22
61
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.2
7.1
27
86
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
10.2
7.1
13
13
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.5
7.0
44
184
RD210, ,
NOMESCO Finland
5.9
7.0
18
31
D06
ICPC
Abdominal pain localized other
2.3
6.9
54
249
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
6.9
124
768
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
6.9
49
217
K70.1
ICD-10 Finland
Alcoholic hepatitis
14.0
6.9
11
8
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
6.2
6.8
17
28
JAH33
NOMESCO Finland
Opening of laparostomy
40.5
6.8
8
*
D73.1
ICD-10 Finland
Hypersplenism
40.5
6.8
8
*
JJ5AT, ,
NOMESCO Finland
40.5
6.8
8
*
JLD12
NOMESCO Finland
Endoscopic drainage of pancreatic pseudocyst
40.5
6.8
8
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.3
6.8
25
78
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
16.9
6.8
10
6
N05CD07
ATC
temazepam; oral
2.0
6.7
79
427
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.7
311
2433
E0000UV, ,
ATC
1.6
6.7
238
1754
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
6.7
117
719
R06AE07
ATC
cetirizine; oral
1.6
6.7
239
1765
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.7
122
760
K81.9
ICD-10 Finland
Cholecystitis, unspecified
7.9
6.6
14
18
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.4
6.6
23
69
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.8
6.6
33
123
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.6
166
1126
SPAT1229
SPAT
Assessment of need for aid
2.4
6.6
45
196
D70.82
ICD-10 Finland
Drug-induced neutropenia
4.2
6.6
17
41
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
8.8
6.6
13
15
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
10.2
6.6
12
12
SPAT1263
SPAT
Sampling
1.6
6.6
239
1771
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
6.3
6.5
16
26
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
70.5
6.4
7
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
70.5
6.4
7
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
14.5
6.4
10
7
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.7
6.4
34
131
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.9
6.3
18
47
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
18.2
6.3
9
5
D73.5
ICD-10 Finland
Infarction of spleen
+∞
6.3
6
*
5612
FHL
Local excisions and / or perforations of relapsing varicose veins
+∞
6.3
6
*
PHE99
NOMESCO Finland
Thrombectomy of other vein
+∞
6.3
6
*
WVA20
NOMESCO Finland
Medicine administration
3.1
6.3
25
82
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
7.1
6.2
14
20
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
7.1
6.2
14
20
K65.9
ICD-10 Finland
Peritonitis, unspecified
27.0
6.2
8
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.1
55
269
SPAT1216
SPAT
Assessment of functional ability
1.8
6.1
95
563
A10BH01
ATC
sitagliptin; oral
2.0
6.1
67
355
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.3
6.1
22
68
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.0
190
1356
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
5.6
6.0
16
29
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.6
6.0
16
29
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.9
6.0
17
44
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
6.0
110
684

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
271
525
8.30
147.91
5.4
2.2
0.17
0.22
g/l
12.21
254
493
167
197
11.17
137.09
4.9
2.6
23.23
20.56
s
1.74
146
179
129
116
13.73
126.93
5.9
2.6
46.37
31.68
umol/l
5.71
122
104
133
142
11.61
116.44
1.3
1.2
94.67
119.00
titre
—
15
10
253
641
5.92
100.36
10.4
2.7
14.87
7.40
umol/l
3.35
234
568
156
245
8.13
99.99
3.5
3.3
530.04
1174.21
u/ml
0.50
141
214
89
64
16.03
99.13
1.1
1.3
—
—
—
0
0
92
76
14.00
94.55
1.2
1.3
3.66
4.52
u/ml
0.22
44
31
233
614
5.44
86.85
5.2
4.4
4.71
34.09
ug/l
1.48
196
516
72
59
13.65
73.96
2.2
2.5
—
—
—
0
0
479
2460
4.95
70.67
14.6
5.1
32.55
35.85
g/l
24.88
467
2326
50
21
25.78
70.63
2.0
2.3
601.65
976.50
e6/l
0.34
31
16
495
2624
5.14
69.52
33.0
13.1
1.44
1.23
inr
11.98
436
2162
338
1377
4.14
68.48
15.3
4.2
76.03
89.90
%
15.80
331
1353
59
39
16.59
68.22
2.2
1.4
—
—
—
0
0
258
876
4.29
67.39
7.4
2.3
32.23
29.39
s
7.17
253
855
358
1552
4.03
65.53
8.9
4.4
—
—
—
0
0
241
801
4.25
64.40
4.2
2.7
21.14
22.47
%
0.74
234
745
45
19
25.43
63.33
1.8
2.2
1136.77
6253.90
e6/l
—
22
10
148
341
5.37
62.71
1.6
1.8
1.32
1.30
g/l
0.04
143
316
43
17
27.07
61.95
2.0
2.2
—
—
—
0
0
166
428
4.91
61.47
2.3
2.9
11.52
10.54
g/l
1.66
160
392
247
870
4.03
60.24
4.1
2.7
2.24
2.30
g/l
0.70
235
804
375
1749
3.83
60.02
6.9
2.6
60.13
62.05
u/l
0.15
360
1626
182
517
4.54
59.48
7.1
2.5
830.74
43.37
u/l
0.79
167
434
507
2931
4.74
58.36
24.0
6.9
18.92
11.93
umol/l
6.44
501
2811
260
991
3.76
55.76
8.8
3.7
0.77
0.82
mmol/l
8.98
254
938
249
931
3.77
54.82
4.2
2.7
11.26
12.99
umol/l
3.37
242
868
376
1836
3.60
54.37
10.1
3.4
44.61
32.55
u/l
5.05
365
1743
39
17
24.39
54.09
1.6
1.1
8.88
16.01
g/l
1.93
23
12
212
776
3.61
47.19
3.3
2.0
—
—
—
0
0
165
511
4.02
46.99
11.7
8.8
8.63
10.06
mmol/l
1.72
159
494
90
170
6.01
46.81
1.5
1.5
194.48
292.62
ug/g
4.33
69
107
164
556
3.64
40.38
1.6
1.6
—
—
—
0
0
176
635
3.46
39.23
1.6
1.6
—
—
—
0
0
347
1850
2.95
38.94
11.3
6.7
—
—
—
0
0
196
760
3.29
38.82
9.2
6.7
1.02
1.05
mmol/l
0.63
186
704
190
730
3.29
38.12
1.5
1.3
451.28
474.29
titre
0.06
39
154
478
3084
3.28
37.06
19.7
10.3
4.76
4.12
e9/l
1.10
421
2671
422
2547
2.99
36.79
11.6
6.7
2.70
2.91
%
1.33
409
2390
422
2559
2.97
36.24
11.8
6.8
9.46
8.98
%
2.18
409
2405
419
2549
2.92
35.43
11.8
6.8
0.71
0.69
%
0.26
404
2389
421
2570
2.92
35.32
11.1
6.7
59.83
57.34
%
3.88
412
2452
425
2616
2.92
34.94
11.7
6.8
24.04
27.51
%
8.99
413
2480
441
2785
2.94
34.22
14.5
7.7
1.20
1.21
mmol/l
2.44
388
2414
246
1152
2.86
34.20
4.3
1.8
2.57
1.11
mg/l
6.60
210
900
321
1726
2.75
34.10
6.9
2.6
—
—
—
0
0
410
2502
2.83
33.81
13.4
7.1
1.20
1.21
mmol/l
3.33
396
2310
44
55
8.53
33.23
1.4
1.2
—
—
—
0
0
435
2768
2.85
32.51
11.0
6.6
0.60
0.60
e9/l
0.01
371
2348
439
2818
2.84
32.05
11.1
6.7
1.57
1.91
e9/l
8.68
384
2463
434
2770
2.82
32.03
11.2
6.6
0.04
0.04
e9/l
0.70
369
2356
32
28
11.99
31.14
1.1
1.1
—
—
—
0
0
440
2854
2.80
30.99
11.9
6.9
0.18
0.20
e9/l
2.25
378
2481
396
2470
2.62
29.63
6.5
2.8
—
—
estimate
—
0
0
141
524
3.18
29.16
14.0
10.3
—
—
—
0
0
301
1659
2.56
29.12
6.4
4.4
7.40
7.40
ph
1.35
227
1184
256
1309
2.61
28.96
6.6
2.5
—
—
—
0
0
291
1583
2.56
28.89
4.2
3.4
0.59
0.37
e6/l
0.77
227
1156
150
581
3.08
28.87
6.0
4.3
1.67
1.87
mmol/l
0.28
124
503
264
1377
2.58
28.57
4.2
2.2
3.79
2.89
mg/l
4.69
242
1173
88
250
3.93
27.48
2.3
1.7
0.38
0.36
mg/l
0.10
37
121
152
609
2.97
27.43
6.1
4.2
7.37
7.39
ph
0.72
96
361
152
609
2.97
27.43
5.8
4.2
5.63
5.75
kpa
0.80
145
590
318
1840
2.47
27.16
4.5
3.5
38.63
90.97
e6/l
0.73
255
1400
50
90
5.95
27.04
2.3
1.7
0.66
0.89
g/l
0.60
44
72
87
248
3.91
27.03
2.6
2.0
4.58
2.38
ug/l
0.54
79
224
163
688
2.85
26.65
4.2
3.0
2.09
1.81
%
2.18
141
628
157
661
2.83
25.70
12.5
8.6
7.42
7.41
ph
0.39
74
363
271
1487
2.44
25.66
4.2
3.4
—
0.00
estimate
—
0
10
172
768
2.71
25.07
1.5
1.3
—
—
—
0
0
156
667
2.78
24.70
12.5
8.5
12.47
12.37
kpa
0.08
151
646
52
109
5.11
23.82
1.1
1.1
—
—
—
0
0
151
652
2.73
23.34
12.7
8.6
0.59
0.87
mmol/l
0.38
130
546
540
4185
3.03
22.23
27.8
8.4
127.39
79.98
u/l
19.09
534
3966
332
2078
2.26
22.22
5.4
4.1
27.28
114.10
e6/l
3.18
265
1476
208
1069
2.41
22.17
4.3
3.0
566.62
546.00
mosm/kgh2o
0.54
187
938
42
78
5.70
21.94
1.1
1.1
—
—
—
0
0
48
102
5.01
21.62
1.9
1.5
161.54
151.89
au/ml
—
10
36
103
377
3.07
21.47
1.3
1.5
—
—
—
0
0
43
86
5.29
20.73
1.1
1.1
—
—
—
0
0
30
15
20.93
20.55
4.1
2.5
0.58
0.62
mmol/l
1.37
30
15
226
1250
2.26
19.93
3.8
2.7
6.34
5.02
e6/l
0.59
212
1147
127
543
2.68
19.75
4.5
3.0
80.55
69.88
e9/l
1.76
92
405
32
22
15.26
19.59
1.1
1.1
—
—
—
0
0
197
1045
2.29
19.07
1.8
1.5
3.32
2.48
g/l
5.16
165
631
47
110
4.54
18.84
1.8
1.5
—
—
—
0
0
355
2404
2.09
18.06
5.8
3.0
201.29
142.72
ug/l
1.97
337
2235
178
932
2.27
17.58
3.5
3.4
2.60
1.76
e6/l
0.67
98
469
24
31
8.01
17.52
32.2
40.3
157.29
125.79
ug/l
0.96
17
25
188
1012
2.22
17.32
3.2
3.2
1.66
1.01
e6/l
0.67
105
549
76
264
3.14
17.20
2.4
2.0
1.33
1.58
g/l
1.03
69
234
459
3459
2.20
17.19
6.2
4.5
57.11
1336.63
e6/l
—
9
56
46
114
4.27
17.15
1.4
1.4
315.17
263.85
u/ml
0.44
29
62
77
272
3.09
16.93
1.3
1.3
—
—
—
0
0
29
51
5.91
16.00
1.2
1.2
—
—
—
0
0
117
530
2.48
15.93
5.8
3.7
4.47
4.44
kpa
0.06
109
513
29
52
5.80
15.68
2.3
2.4
44.85
76.42
iu/ml
—
6
5
189
1056
2.13
15.61
4.4
4.0
252.30
451.03
ng/l
0.57
147
839
115
526
2.45
15.29
1.7
1.4
—
—
—
0
0
246
1529
2.00
15.10
3.6
3.2
—
—
—
0
0
349
2448
1.95
14.99
25.8
11.6
0.16
0.00
e9/l
0.56
278
2000
469
3651
2.11
14.89
10.8
3.4
131.89
49.76
u/l
17.53
455
3432
131
665
2.22
13.59
1.5
1.3
—
—
—
0
0
103
476
2.39
13.29
2.6
3.0
64.87
66.93
g/l
1.63
92
447
282
1915
1.86
12.68
6.2
3.6
2.33
2.35
mmol/l
1.82
265
1746
124
641
2.16
12.20
2.1
1.6
—
—
—
0
0
137
747
2.07
11.69
1.9
1.8
—
—
—
0
0
41
124
3.47
11.56
1.3
1.9
1.08
0.92
nmol/l
0.25
35
102
130
700
2.08
11.45
1.9
1.5
—
—
—
0
0
21
20
10.82
11.34
2.2
5.6
—
—
—
0
0
88
409
2.34
11.14
8.2
3.9
7.42
7.42
ph
0.09
74
339
47
161
3.07
10.85
1.5
1.4
—
—
—
0
0
31
82
3.92
10.60
1.6
1.4
—
—
—
0
0
74
327
2.43
10.47
3.3
2.8
0.65
0.62
%
0.32
74
327
27
67
4.17
10.05
2.4
3.0
4.75
85.29
nmol/l
0.50
27
67
99
504
2.14
10.03
7.0
4.5
1.03
0.82
%
0.47
60
177
154
919
1.89
9.99
2.1
1.7
1153.46
1170.23
nmol/l
0.07
118
701
40
135
3.10
9.48
1.2
1.2
—
—
—
0
0
93
475
2.12
9.32
7.3
4.5
0.83
0.49
%
1.15
54
160
24
59
4.19
9.05
1.3
1.4
—
—
—
0
0
316
2372
1.67
8.98
3.6
2.5
74.51
77.67
nmol/l
1.22
289
2122
327
2481
1.66
8.87
2.5
2.1
89.23
94.97
pmol/l
1.48
192
1331
100
535
2.03
8.84
2.6
2.2
387.21
383.71
nmol/l
0.03
90
498
23
56
4.22
8.78
1.6
1.1
—
—
—
0
0
293
2174
1.65
8.58
5.4
3.9
30.92
68.44
ng/l
0.81
237
1602
21
49
4.40
8.46
2.1
1.2
3.30
2.91
g/l
0.39
15
36
21
49
4.40
8.46
2.1
1.2
0.47
0.42
g/l
0.26
15
35
21
49
4.40
8.46
2.1
1.2
6.45
7.07
g/l
0.30
15
36
91
478
2.06
8.44
6.9
4.6
0.10
0.12
%
0.18
52
151
18
23
8.02
8.41
3.4
2.4
1.64
1.97
umol/l
0.61
18
16
17
20
8.70
8.35
1.1
1.5
31.47
26.85
s
1.36
17
20
109
620
1.92
8.05
3.3
2.5
300.92
134.68
ug/g
2.71
99
505
90
479
2.03
8.05
7.7
5.0
0.04
0.09
%
0.29
47
132
78
395
2.11
7.96
2.1
2.6
—
—
—
0
0
34
116
3.04
7.93
1.5
1.7
—
—
—
0
0
33
111
3.08
7.88
1.4
1.3
52.87
64.21
mmol/l
1.13
23
96
28
85
3.40
7.88
1.8
2.2
0.97
0.94
%
0.11
21
61
18
26
7.09
7.82
3.7
2.3
25.67
29.38
umol/l
0.37
18
21
181
1212
1.69
7.71
7.6
4.8
—
—
—
0
0
229
1634
1.63
7.60
14.3
6.7
—
—
—
0
0
14
14
10.20
7.56
3.6
4.5
3882.21
6.71
ug/l
0.79
14
14
33
114
3.00
7.54
4.6
4.4
2.69
2.33
mmol/l
0.32
20
77
213
1497
1.64
7.49
4.1
2.8
347.78
350.04
umol/l
0.12
187
1321
81
430
2.01
7.28
6.5
4.2
1.23
1.23
mmol/l
0.06
75
376
278
2095
1.59
7.27
2.6
2.2
—
—
—
0
0
170
1141
1.67
7.10
5.4
2.9
2.48
2.45
mmol/l
2.16
151
1033
34
124
2.84
7.07
3.4
3.9
—
—
—
0
0
20
52
3.94
7.03
2.0
1.2
—
—
—
0
0
237
1732
1.59
7.00
2.8
3.3
1561.17
1347.30
ng/l
0.28
194
1480
38
148
2.67
6.99
5.7
3.2
2.04
2.53
index
0.20
23
88
47
205
2.40
6.86
1.3
1.2
—
—
—
0
0
36
141
2.65
6.56
10.8
5.9
1.93
1.42
mmol/l
0.70
28
122
65
333
2.06
6.44
6.8
4.2
—
—
—
0
0
43
186
2.41
6.40
1.8
2.5
11.23
10.55
g/l
0.34
37
172
41
174
2.45
6.35
11.3
3.3
8.78
8.41
kpa
0.51
41
169
170
1170
1.62
6.34
1.4
1.3
0.97
1.93
u/ml
1.19
40
309
33
128
2.67
6.14
1.7
1.9
—
—
—
0
0
14
21
6.79
6.06
1.1
1.1
—
—
—
0
0
21
63
3.41
6.05
1.9
2.8
10.72
10.25
%
0.17
21
63
222
1646
1.54
5.95
2.1
1.7
20.87
19.97
nmol/l
0.36
203
1390
14
22
6.48
5.88
1.0
1.0
—
—
—
0
0
10
9
11.27
5.81
1.4
1.3
—
—
—
0
0
21
65
3.31
5.77
6.5
4.6
—
—
—
0
0
232
1747
1.52
5.74
2.8
2.2
220.51
248.47
u/l
0.19
227
1665
57
296
2.02
5.46
10.7
4.2
—
—
—
0
0
33
139
2.45
5.23
2.4
2.3
61.45
60.78
%
0.05
33
139
73
419
1.84
5.21
5.6
4.3
83.78
86.56
ng/l
0.09
65
371
33
141
2.41
5.08
2.6
3.7
—
—
—
0
0
70
400
1.84
5.06
3.1
3.2
206.81
194.94
ng/l
0.08
64
358
31
129
2.48
5.04
2.7
2.5
91.73
90.04
%
0.86
31
124
21
73
2.94
4.80
3.1
2.7
4.34
4.07
mmol/l
0.99
21
73
21
73
2.94
4.80
3.1
2.7
105.14
104.58
mmol/l
0.22
21
73
40
194
2.13
4.61
2.4
3.2
1.59
2.10
ratio
0.59
26
114
41
202
2.10
4.54
4.3
5.1
325.07
325.19
mg/l
0.00
27
94
198
1503
1.46
4.50
1.6
1.4
—
—
—
0
0
21
76
2.82
4.49
3.0
1.7
—
—
—
0
0
21
76
2.82
4.49
3.0
1.7
—
—
—
0
0
21
76
2.82
4.49
3.0
1.7
—
—
—
0
0
21
76
2.82
4.49
3.0
1.7
—
—
—
0
0
42
211
2.06
4.42
2.5
3.5
52.75
76.29
mg/l
0.37
35
180
42
211
2.06
4.42
2.5
3.5
32.41
41.31
mg/l
0.38
35
181
13
29
4.55
4.26
1.2
1.2
161.38
139.15
nmol/l
0.39
13
29
20
73
2.80
4.22
5.3
2.0
10.55
10.92
mmol/l
0.19
20
73
103
691
1.59
4.16
4.6
3.3
5.71
5.73
e9/l
0.00
90
606
8
10
8.09
4.07
1.1
1.2
—
—
—
0
0
22
87
2.58
4.00
1.9
2.2
31.18
32.76
pg
1.03
22
87
16
54
3.01
3.87
1.5
1.3
5327.78
25799.48
e6/l
—
9
29
557
5186
1.64
3.87
48.7
16.3
35.47
25.27
mg/l
9.31
541
4308
19
72
2.69
3.76
3.3
2.7
1.20
1.18
mmol/l
0.42
19
72
105
724
1.54
3.76
1.4
1.3
—
—
—
0
0
66
408
1.69
3.68
5.3
3.5
—
—
—
0
0
8
12
6.74
3.68
2.6
1.5
—
—
—
0
0
248
2017
1.38
3.68
3.7
3.5
7.50
7.95
mmol/l
0.69
209
1704
9
16
5.69
3.67
1.6
2.3
—
—
—
0
0
339
2904
1.36
3.59
5.0
3.8
0.00
0.56
estimate
0.52
82
555
15
51
2.99
3.59
2.4
2.4
647.00
592.32
ml
—
10
28
75
483
1.63
3.58
2.4
2.4
4.18
7.36
ug/l
2.53
59
430
16
57
2.85
3.54
1.5
1.3
3413.00
2132.11
e6/l
—
9
36
167
2122
0.71
3.51
3.9
3.3
—
—
—
0
0
336
2883
1.35
3.48
5.1
3.8
13.10
0.00
estimate
0.49
92
590
15
52
2.93
3.48
1.5
1.6
—
—
—
0
0
242
1975
1.37
3.46
4.7
4.2
16.89
9.09
mg/mmol
0.91
155
1258
30
147
2.09
3.42
1.2
1.1
—
—
—
0
0
237
1939
1.36
3.30
3.8
3.4
81.74
53.53
mg/l
0.66
159
1265
331
2856
1.33
3.20
5.0
3.8
0.00
0.00
estimate
-0.00
90
589
8
15
5.39
3.20
1.1
1.1
—
—
—
0
0
63
401
1.63
3.17
1.2
1.2
—
—
—
0
0
190
1514
1.37
3.10
3.6
3.1
—
0.07
—
0
42
6
8
7.56
3.06
1.0
1.1
—
—
—
0
0
13
45
2.93
3.04
1.2
1.1
—
—
—
0
0
12
36
3.38
3.03
5.0
3.0
1.00
0.86
index
0.24
12
36
40
228
1.81
2.98
1.4
1.6
7.08
8.59
iu/ml
—
5
57
76
514
1.54
2.97
6.7
4.5
7.36
7.36
ph
0.08
68
379
272
2303
1.32
2.91
4.0
3.5
6.20
6.19
ph
0.06
145
1337
14
52
2.73
2.90
1.5
1.4
—
—
—
0
0
14
52
2.73
2.90
1.8
1.3
—
—
—
0
0
7
13
5.43
2.87
2.3
4.5
3.08
1.09
ug/l
—
7
13
14
53
2.68
2.81
1.3
1.5
—
—
—
0
0
7
15
4.71
2.60
2.4
1.7
—
—
—
0
0
5
7
7.19
2.55
1.2
1.3
—
—
—
0
0
7
17
4.15
2.36
1.3
1.6
—
—
—
0
0
112
1434
0.73
2.31
2.9
3.2
0.59
0.73
ug/l
2.21
69
900
18
85
2.15
2.30
1.8
2.7
—
—
—
0
0
17
79
2.18
2.26
4.8
3.1
3.79
4.79
e9/l
1.18
17
79
13
54
2.44
2.21
1.2
1.1
—
—
—
0
0
8
24
3.36
2.18
1.9
2.0
74.00
60.10
ug/l
—
8
24
22
115
1.95
2.18
4.6
2.9
62.55
59.10
%
0.57
22
115
14
61
2.32
2.16
2.2
1.6
—
—
—
0
0
7
19
3.71
2.15
1.0
1.2
—
—
—
0
0
6
14
4.32
2.15
4.2
1.7
—
—
—
0
0
9
30
3.03
2.15
1.9
2.3
—
—
—
0
0
11
42
2.65
2.15
1.2
1.1
—
—
—
0
0
187
1561
1.28
2.10
5.1
3.2
0.00
0.06
estimate
0.60
76
475
27
452
0.58
2.09
1.6
1.4
—
—
—
0
0
11
43
2.59
2.09
2.4
1.4
1.29
1.12
promille
0.12
11
35
17
82
2.10
2.08
1.1
1.2
—
—
—
0
0
17
82
2.10
2.08
1.1
1.2
—
—
—
0
0
9
32
2.84
2.00
1.1
1.3
4.69
6.49
ug/l
—
9
27
143
1160
1.30
1.99
1.8
1.7
521.43
16253021.52
pmol/l
0.69
116
966
495
5203
0.77
1.86
6.0
5.3
1.33
1.43
mmol/l
5.57
460
4817
6
17
3.55
1.84
3.7
1.5
—
—
—
0
0
40
263
1.56
1.84
2.9
2.3
—
—
—
0
0
231
2005
1.24
1.83
4.8
3.7
—
0.71
—
0
7
5
12
4.19
1.82
2.2
1.8
—
—
—
0
0
6
18
3.35
1.75
1.8
1.7
26.33
34.28
%
—
6
18
154
1287
1.26
1.69
3.7
3.7
—
0.23
—
0
13
8
31
2.60
1.66
3.4
1.5
20.51
21.85
umol/l
—
8
26
8
31
2.60
1.66
2.6
1.6
96.00
77.39
umol/l
—
8
31
8
31
2.60
1.66
4.3
2.1
—
—
—
0
0
11
49
2.27
1.64
1.0
1.1
—
—
—
0
0
10
42
2.40
1.62
2.8
3.3
31.69
45.84
u/ml
—
10
42
45
313
1.47
1.62
1.1
1.2
59.99
141.20
u/ml
1.68
14
121
8
32
2.52
1.60
1.0
1.2
—
—
—
0
0
24
382
0.61
1.56
1.6
1.8
3.79
3.53
mmol/l
0.62
17
292
501
5233
0.79
1.54
6.1
5.4
4.38
4.59
mmol/l
4.62
468
4875
8
33
2.44
1.54
3.5
3.0
1501.00
1146.64
u/ml
—
8
33
17
93
1.85
1.53
2.3
3.1
1.02
0.81
nmol/l
—
6
76
0
45
0.00
1.50
0.0
1.0
—
270.00
—
0
26
8
170
0.46
1.48
1.3
1.1
1.39
1.52
g/l
—
8
170
10
45
2.24
1.47
2.1
3.1
14.35
16.72
%
—
10
45
560
5402
1.33
1.46
52.0
19.5
138.66
139.71
mmol/l
15.62
553
5303
7
29
2.43
1.39
1.0
1.1
—
—
—
0
0
7
29
2.43
1.39
1.1
1.1
—
—
—
0
0
560
5413
1.31
1.34
52.8
19.7
3.97
3.99
mmol/l
1.14
553
5303
23
145
1.61
1.30
5.5
4.7
—
—
—
0
0
182
1590
1.20
1.30
5.5
3.8
0.00
0.01
estimate
0.78
80
532
40
288
1.42
1.25
3.7
3.9
4.16
4.50
pmol/l
1.59
35
250
11
56
1.98
1.22
1.2
1.1
—
—
—
0
0
69
545
1.30
1.21
1.7
1.5
—
—
—
0
0
29
198
1.49
1.19
1.2
1.1
—
2.14
—
0
9
17
270
0.62
1.15
1.2
1.1
—
—
—
0
0
26
177
1.49
1.09
1.7
1.7
12.97
15.14
u/ml
—
6
46
5
21
2.39
1.09
2.0
1.2
—
—
—
0
0
515
5317
0.83
1.03
6.7
6.1
2.51
2.69
mmol/l
4.64
477
4934
9
47
1.93
1.02
1.7
3.0
7.18
8.69
mmol/l
—
9
47
10
176
0.56
1.01
1.0
1.1
—
—
—
0
0
22
150
1.48
0.94
3.0
2.4
67.71
83.21
ug/min
0.14
14
88
11
63
1.76
0.90
1.1
1.2
—
—
—
0
0
28
203
1.40
0.89
2.0
2.0
44.50
39.96
nmol/l
0.36
28
195
6
30
2.01
0.87
1.7
1.5
—
—
—
0
0
6
30
2.01
0.87
1.0
1.1
—
—
—
0
0
238
2192
1.14
0.83
5.2
3.7
0.00
0.02
estimate
1.40
75
499
8
47
1.71
0.81
1.3
1.7
—
—
—
0
0
22
156
1.43
0.80
2.2
1.5
10336.50
14702.12
e6/l
0.30
12
108
0
25
0.00
0.79
0.0
1.2
—
0.48
—
0
14
11
66
1.68
0.79
1.4
1.2
—
—
—
0
0
12
74
1.63
0.78
1.1
1.1
—
—
—
0
0
10
59
1.71
0.76
2.1
2.5
—
—
—
0
0
31
238
1.32
0.72
2.0
3.0
—
—
—
0
0
10
61
1.65
0.69
11.4
7.8
10.74
6.91
mmol/l
—
10
50
31
242
1.30
0.65
1.0
1.1
—
113.50
—
0
6
7
44
1.60
0.65
1.1
1.3
—
—
—
0
0
19
137
1.40
0.65
1.2
1.7
369.63
266.87
mu/l
0.70
19
131
5
30
1.67
0.61
1.6
1.3
7.47
7.34
ph
—
5
22
219
2340
0.90
0.59
4.6
5.4
1.91
2.69
ug/l
0.95
191
2119
11
72
1.54
0.59
1.5
1.3
—
—
—
0
0
34
275
1.25
0.56
2.1
1.7
—
—
—
0
0
488
4999
0.89
0.54
5.3
4.5
1.44
1.31
mmol/l
2.08
447
4596
15
108
1.40
0.53
1.6
1.4
—
—
—
0
0
219
2323
0.91
0.50
2.2
2.0
1.56
1.38
mmol/l
1.80
193
1950
46
539
0.84
0.50
1.5
1.5
—
—
—
0
0
6
41
1.47
0.50
1.5
1.2
98.00
104.80
pmol/l
—
6
41
13
93
1.41
0.48
1.4
1.7
—
—
—
0
0
17
129
1.33
0.46
2.0
1.5
—
—
—
0
0
57
502
1.15
0.42
3.0
2.3
0.00
0.03
estimate
—
10
98
505
5144
0.91
0.41
6.0
5.3
6.38
6.01
mmol/l
5.65
460
4715
30
250
1.21
0.41
2.4
1.8
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
25.64
—
0
11
8
61
1.32
0.39
1.3
2.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
0.16
—
0
19
544
5360
1.11
0.37
40.5
14.5
—
—
—
0
0
10
134
0.74
0.35
1.1
1.6
—
—
—
0
0
17
211
0.80
0.35
3.0
1.7
—
—
—
0
0
14
178
0.78
0.34
1.0
1.1
—
—
—
0
0
10
133
0.75
0.33
1.5
1.8
2.62
4.50
iu/l
—
5
60
560
5533
1.11
0.32
33.8
12.3
36.07
26.95
u/l
12.61
552
5385
17
138
1.24
0.30
2.1
1.5
—
—
—
0
0
562
5678
0.91
0.30
69.4
25.0
126.55
136.32
g/l
29.37
557
5615
7
56
1.25
0.29
3.3
2.4
—
—
—
0
0
17
139
1.23
0.29
2.1
1.5
—
—
—
0
0
21
176
1.20
0.29
3.1
1.2
0.96
0.92
g/l
0.27
21
176
562
5676
0.91
0.28
68.7
24.9
7.57
6.75
e9/l
1.18
552
5554
562
5676
0.91
0.28
68.7
24.8
4.29
4.51
e12/l
13.17
550
5555
103
965
1.08
0.27
1.3
1.3
26.71
33.65
iu/ml
0.41
29
294
562
5674
0.91
0.27
68.8
24.9
234.69
246.63
e9/l
1.88
553
5565
8
66
1.21
0.27
1.1
1.3
—
—
nmol/l
—
0
0
17
141
1.21
0.26
2.1
1.5
—
—
—
0
0
5
71
0.70
0.26
4.4
2.5
—
—
—
0
0
96
901
1.08
0.25
1.3
1.3
7.35
12.23
u/ml
0.39
26
344
20
170
1.18
0.25
2.2
2.0
198.05
213.66
pmol/l
0.32
20
157
10
78
1.29
0.24
1.2
1.2
—
—
—
0
0
405
3974
1.05
0.24
4.3
4.1
14.92
14.84
pmol/l
0.23
368
3615
13
107
1.22
0.21
2.1
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
1.76
—
0
10
30
268
1.13
0.21
3.7
2.4
0.00
3.18
estimate
—
5
79
0
13
0.00
0.21
0.0
2.2
—
19.18
—
0
13
0
13
0.00
0.21
0.0
1.1
—
39.39
—
0
13
0
14
0.00
0.20
0.0
1.1
—
0.69
—
0
9
6
50
1.20
0.19
1.7
2.9
220.17
1013.60
mg
—
6
50
16
139
1.16
0.16
2.1
1.5
—
—
—
0
0
48
448
1.08
0.16
1.3
1.4
—
—
—
0
0
38
352
1.08
0.15
1.2
1.3
—
—
—
0
0
130
1261
1.04
0.12
4.7
3.8
1.02
2.20
kg/l
0.50
101
856
13
145
0.89
0.09
1.2
1.2
—
—
—
0
0
8
77
1.04
0.07
1.1
1.3
0.84
24.54
nmol/l
—
8
71
15
163
0.92
0.07
15.0
10.3
—
—
—
0
0
9
88
1.02
0.07
1.1
1.3
71.79
42.43
mu/l
—
9
78
502
5044
0.98
0.07
8.9
6.7
43.08
39.64
mmol/mol
4.79
472
4728
8
94
0.85
0.06
1.1
1.1
—
18.09
—
0
26
33
345
0.95
0.06
1.2
1.3
—
54.50
—
0
28
560
5585
1.02
0.04
56.3
21.4
79.98
80.18
umol/l
0.04
555
5526
60
586
1.03
0.04
2.6
2.3
12.68
13.75
nmol/l
0.40
51
541
44
429
1.03
0.03
3.1
2.5
5.89
6.03
ph
0.64
36
296
10
93
1.08
0.02
3.8
2.6
—
—
—
0
0
12
113
1.06
0.02
1.3
2.0
—
—
—
0
0
482
4812
1.01
0.01
5.4
5.1
2.01
1.94
mu/l
0.46
443
4416
12
122
0.98
0.00
1.3
1.3
—
—
—
0
0
23
228
1.01
0.00
1.3
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
214.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
48.43
—
0
7
0
7
0.00
-0.00
0.0
5.4
—
8.71
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
402.00
—
0
5
5
56
0.89
-0.00
1.4
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
40.00
—
0
6
6
62
0.97
-0.00
1.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
7.22
—
0
7

Mortality – FinRegistry

Association

Association between endpoint I9_PVT and mortality.

Females

Parameter HR [95% CI] p-value
I9_PVT 2.849 [2.24, 3.63] < 0.001
Birth year 0.997 [0.99, 1.01] 0.487

During the follow-up period (1.1.1998 — 31.12.2019), 395 out of 988 females with I9_PVT died.

Males

Parameter HR [95% CI] p-value
I9_PVT 4.077 [3.25, 5.12] < 0.001
Birth year 0.987 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 649 out of 1429 males with I9_PVT died.

Mortality risk

Mortality risk for people of age

years, who have I9_PVT.

N-year risk Females Males
1 0.295% 0.843%
5 1.882% 4.944%
10 4.634% 12.337%
15 8.574% 21.809%
20 14.689% 34.055%

Relationships between endpoints

Index endpoint: I9_PVT – Portal vein thrombosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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