No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
289 |
4. Check minimum number of eventsNone |
289 |
5. Include endpointsNone |
289 |
6. Filter based on genotype QC (FinnGen only) |
268 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H92
- Name in latin
- Otorrhagia
Similar endpoints
↥List of similar endpoints to
Otorrhagia
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1851 | 828 | 1014 |
| Only index persons | 1598 | 720 | 878 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 56.80 | 63.46 | 51.22 |
| Only index persons | 59.29 | 66.15 | 53.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 268 | 125 | 143 |
| Unadjusted period prevalence (%) | 0.06 | 0.04 | 0.07 |
| Median age at first event (years) | 64.59 | 64.62 | 64.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 276
- Matched controls
- 2760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H92.2
ICD-10 Finland
Otorrhagia
+∞
307.7
276
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
26.8
77.4
56
26
UDC00
NOMESCO Finland
Ear microscopy
10.9
43.6
51
56
DFF00
NOMESCO Finland
Pure tone audiometry
11.1
36.9
42
44
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.9
36.2
65
118
H05
ICPC
Bleeding ear
95.4
24.1
26
*
H92.0
ICD-10 Finland
Otalgia
6.2
20.2
37
67
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
7.6
16.4
24
34
AA1AD
NOMESCO Finland
CT of head and brain
2.8
14.6
113
553
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
56.4
14.0
16
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
13.2
104
509
R04.0
ICD-10 Finland
Epistaxis
3.9
13.0
42
122
B01AA03
ATC
warfarin; systemic
2.8
12.6
80
350
Z97.4
ICD-10 Finland
Presence of external hearing-aid
24.1
11.7
16
7
H29
ICPC
Ear symptom/complaint other
3.4
11.6
47
158
H65.3
ICD-10 Finland
Chronic mucoid otitis media
8.5
10.8
23
29
H02AB06
ATC
prednisolone; systemic
2.3
10.8
149
923
DAX08
NOMESCO Finland
Fitting of hearing aid
22.5
10.8
15
7
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.5
10.6
89
443
C03CA01
ATC
furosemide; systemic
2.4
10.5
115
643
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
10.5
159
1021
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
+∞
10.5
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
10.5
92
467
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
9.3
10.0
20
23
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.7
9.5
61
265
ZXA05
NOMESCO Finland
Left side
2.4
9.5
86
440
A02BC02
ATC
pantoprazole; systemic
2.4
9.4
198
1431
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
9.2
132
815
N03AX16
ATC
[U] pregabalin
2.4
9.2
77
380
R4110
NOMESCO Finland
Physiotherapy
2.3
9.1
100
554
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
9.0
206
1528
I50
ICD-10 Finland
Heart failure
5.2
9.0
19
39
Z3229
NOMESCO Finland
Other healthcare associate professional
3.5
8.9
32
99
R51.80
ICD-10 Finland
Headache
2.6
8.9
57
247
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.1
8.9
40
143
C01DA14
ATC
isosorbide mononitrate; oral
2.6
8.8
62
281
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.6
8.8
30
90
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.7
8.8
29
85
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
51.7
8.7
10
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.0
8.7
43
162
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
17.0
8.6
13
8
H01
ICPC
Ear pain/earache
2.8
8.5
46
182
ZXD05
NOMESCO Finland
Urgent procedure
2.2
8.5
98
552
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
8.5
79
407
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.5
8.4
21
50
WX892
NOMESCO Finland
Monitored bed care
3.2
8.3
34
115
A01
ICPC
Pain general/multiple sites
2.9
8.2
41
155
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
8.2
94
526
N02AX02
ATC
tramadol; systemic, rectal
2.1
8.2
135
868
H71
ICD-10 Finland
Cholesteatoma of middle ear
17.8
8.1
12
7
Z3231
NOMESCO Finland
Registered nurse
2.1
7.8
95
543
C10AA05
ATC
atorvastatin; oral
2.1
7.8
129
827
R50.9
ICD-10 Finland
Fever, unspecified
2.4
7.8
59
276
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
7.8
121
759
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
46.3
7.8
9
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
7.7
65
320
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
19.0
7.7
11
6
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
12.3
7.7
13
11
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
7.6
82
446
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.4
7.6
62
300
H93.1
ICD-10 Finland
Tinnitus
6.8
7.5
18
28
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.3
7.5
29
94
TFP20
NOMESCO Finland
Cardiodefibrillation
3.1
7.5
33
116
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.2
7.5
20
50
AN1
HP
Coronary angiography
2.6
7.3
45
190
S29
ICPC
Skin symptom/complaint other
2.3
7.3
66
333
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.2
7.3
80
437
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
7.3
50
223
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
7.3
29
96
M79.1
ICD-10 Finland
Myalgia
2.5
7.1
50
225
H65.2
ICD-10 Finland
Chronic serous otitis media
10.4
7.1
13
13
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
7.0
52
240
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
7.0
117
746
C07AB07
ATC
bisoprolol; oral
2.0
7.0
153
1070
207
Kela drug reimbursment
Chronic arrhythmias
2.3
6.9
59
290
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.2
6.9
29
99
L17
ICPC
Foot/toe symptom/complaint
2.0
6.9
94
556
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.7
6.9
41
170
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
6.9
63
319
S76
ICPC
Skin infection other
3.5
6.9
24
73
R5120
NOMESCO Finland
Preparation of an aid
9.7
6.9
13
14
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
6.8
63
321
UJF32
NOMESCO Finland
Coloscopy
2.1
6.8
79
441
A11
ICPC
Chest pain NOS
2.9
6.8
34
129
Z02.7
ICD-10 Finland
Issue of medical certificate
3.1
6.8
30
106
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
6.8
67
351
S18
ICPC
Laceration/cut
1.9
6.7
142
977
B01AC04
ATC
clopidogrel; oral
2.2
6.6
64
331
H81.0
ICD-10 Finland
Ménière disease
10.4
6.6
12
12
S01.3
ICD-10 Finland
Open wound of ear
10.4
6.6
12
12
M79.6
ICD-10 Finland
Pain in limb
1.9
6.6
128
855
XF402
NOMESCO Finland
ECG with work load test
2.6
6.6
39
162
J01DB01
ATC
cefalexin; oral
2.3
6.5
230
1884
Z2221
NOMESCO Finland
Medical doctor
2.0
6.5
87
510
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
71.4
6.5
7
*
Z3226
NOMESCO Finland
Physiotherapist
2.2
6.4
66
350
A46
ICD-10 Finland
Erysipelas
2.3
6.4
52
250
WX402
NOMESCO Finland
General anaesthesia
2.1
6.4
69
373
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
6.3
6
*
J01AA02
ATC
doxycycline; systemic
2.1
6.2
208
1650
J01FF01
ATC
clindamycin; systemic
2.0
6.2
82
477
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
6.1
27
95
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
6.1
37
155
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
6.1
62
327
DFF15
NOMESCO Finland
Speech audiometry
10.4
6.1
11
11
H53.1
ICD-10 Finland
Subjective visual disturbances
3.1
6.1
26
90
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.1
6.0
25
85
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
185
1128
2.94
15.98
30.2
14.8
1.42
1.28
inr
2.27
165
940
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
72
4.55
11.86
6.4
2.7
0.26
0.33
iu/ml
0.74
20
34
119
652
2.45
11.66
2.6
2.3
2.52
3.05
mg/l
1.83
107
571
164
1086
2.26
9.80
5.0
3.2
154.84
120.72
ug/l
0.56
154
1012
163
1087
2.22
9.44
8.3
5.5
35.71
35.39
g/l
0.30
154
1036
167
1125
2.23
9.42
14.3
7.8
1.20
1.21
mmol/l
1.62
158
1048
128
785
2.18
9.05
5.0
3.2
2141.63
1569.66
ng/l
0.51
115
677
90
485
2.27
8.70
6.7
3.7
150.58
247.63
ng/l
0.50
71
404
180
1274
2.19
8.65
8.3
7.1
15.52
14.48
umol/l
0.24
175
1214
84
442
2.29
8.58
2.6
1.9
—
—
—
0
0
156
1058
2.09
8.22
3.9
2.9
—
—
estimate
—
0
0
99
568
2.16
8.11
4.0
2.6
—
—
—
0
0
193
1427
2.17
7.98
10.4
6.1
6.90
6.71
mmol/l
0.49
184
1349
174
1240
2.09
7.89
15.9
8.3
1.19
1.21
mmol/l
2.46
159
1090
44
178
2.75
7.81
4.9
2.7
49.95
64.88
ml/min/173m2
1.58
19
78
118
735
2.06
7.70
2.5
2.1
163.91
390.73
u/l
1.00
112
696
153
1049
2.03
7.62
3.4
2.6
77.16
76.60
nmol/l
0.09
138
950
227
1809
2.44
7.57
11.6
8.3
84.03
84.05
u/l
0.00
221
1705
151
1036
2.01
7.45
2.7
2.2
91.08
95.26
pmol/l
0.56
78
536
69
353
2.27
7.42
2.4
1.8
—
—
—
0
0
72
379
2.22
7.21
13.2
6.8
1.14
1.11
mmol/l
0.32
66
349
41
167
2.71
7.17
2.3
1.6
—
—
—
0
0
95
562
2.05
7.01
2.9
2.0
0.99
1.60
mg/l
1.67
73
440
185
1400
1.97
6.49
12.0
10.8
4.08
4.17
e9/l
0.22
157
1189
133
913
1.88
6.17
6.2
4.0
27.43
46.12
ng/l
1.96
99
683
110
717
1.89
5.94
2.0
1.7
20.70
20.70
nmol/l
0.00
97
604
99
630
1.89
5.72
3.9
3.1
358.93
353.97
umol/l
0.15
91
555
111
734
1.86
5.68
3.7
2.6
57.75
70.34
u/l
0.76
104
687
49
243
2.24
5.59
3.3
2.5
29.55
38.01
u/l
0.89
40
194
214
1747
2.00
5.48
4.9
4.2
14.99
14.93
pmol/l
0.13
203
1585
28
108
2.77
5.41
3.7
1.5
0.20
0.25
mg/l
0.23
12
41
77
463
1.92
5.22
4.2
3.2
2.00
2.99
e6/l
0.65
47
218
62
349
2.00
5.07
2.6
1.8
—
—
—
0
0
57
315
2.02
4.90
11.2
8.3
0.87
0.87
mmol/l
0.00
51
263
54
294
2.04
4.83
4.4
4.0
10.09
7.49
umol/l
0.36
49
264
120
847
1.74
4.73
4.2
3.4
2.35
2.35
mmol/l
0.01
111
781
241
2091
2.20
4.70
6.3
5.2
2.03
1.94
mu/l
0.56
227
1924
210
1739
1.87
4.68
5.1
4.3
13.51
12.31
mm/h
0.47
196
1624
175
1374
1.75
4.68
3.5
3.0
—
—
—
0
0
78
490
1.82
4.55
3.7
3.2
1.28
1.11
e6/l
0.14
48
244
83
532
1.80
4.53
1.4
1.4
3.25
1.17
u/ml
0.52
17
138
255
2280
2.56
4.36
30.8
17.1
24.68
26.62
mg/l
0.46
229
1868
21
79
2.79
4.26
2.1
1.6
—
—
—
0
0
65
394
1.85
4.22
12.7
8.3
103.68
104.16
mmol/l
0.34
65
394
17
58
3.06
4.08
1.5
1.5
333.80
300.01
ug/g
—
10
33
113
819
1.64
3.84
4.5
3.5
7.70
7.70
mmol/l
0.00
100
684
7
8
8.94
3.79
2.4
4.4
323.57
247.00
nmol/l
—
7
8
18
67
2.80
3.74
2.1
1.3
—
—
—
0
0
63
398
1.76
3.53
1.9
1.8
1090.79
1182.87
nmol/l
0.37
47
310
241
2146
1.97
3.53
5.7
5.0
6.00
6.02
mmol/l
0.08
227
1973
29
140
2.20
3.53
2.2
1.3
—
—
—
0
0
234
2068
1.86
3.45
5.1
4.3
1.26
1.28
mmol/l
0.25
215
1898
9
18
5.13
3.40
1.1
1.1
—
—
—
0
0
104
761
1.59
3.30
4.5
3.4
0.19
0.40
e6/l
2.38
78
548
18
72
2.60
3.28
2.4
1.8
—
—
—
0
0
6
7
8.73
3.28
2.8
2.1
0.62
0.63
mmol/l
—
6
7
7
11
6.50
3.20
1.1
1.3
—
—
—
0
0
154
1238
1.55
3.20
4.5
4.2
0.00
6.04
estimate
0.50
20
269
18
75
2.50
3.04
2.7
1.9
—
—
—
0
0
152
1229
1.53
3.00
4.6
4.1
0.00
0.00
estimate
-0.00
21
265
45
270
1.80
2.99
2.6
1.8
1.66
1.57
%
0.30
40
234
78
544
1.60
2.98
4.2
4.5
1.02
1.02
kg/l
0.24
54
373
240
2166
1.83
2.91
6.1
5.1
4.15
4.54
mmol/l
7.33
223
2016
154
1256
1.51
2.87
4.7
4.2
0.19
1.15
estimate
0.39
21
262
264
2469
2.59
2.82
45.1
25.6
4.38
4.49
e12/l
2.75
258
2407
35
198
1.88
2.80
1.5
1.6
—
—
—
0
0
243
2208
1.84
2.79
7.1
5.8
2.37
2.63
mmol/l
4.61
226
2049
11
34
3.33
2.76
1.7
1.4
—
—
—
0
0
238
2159
1.74
2.62
6.1
5.0
1.37
1.44
mmol/l
2.17
220
1997
17
75
2.35
2.56
1.6
1.5
—
—
—
0
0
263
2469
2.38
2.53
45.3
25.7
234.86
247.53
e9/l
2.24
258
2418
217
1929
1.58
2.52
39.8
22.3
330.11
332.55
g/l
3.24
217
1921
177
1517
1.46
2.37
4.5
3.4
53.68
50.51
u/l
0.20
169
1424
102
788
1.47
2.37
5.0
4.2
14.69
12.55
mg/mmol
0.12
72
495
19
92
2.14
2.33
2.4
4.3
23.07
24.22
mmol/l
0.87
19
92
234
2132
1.64
2.29
29.2
16.7
76.80
80.05
ml/min/173m2
1.19
221
1977
5
9
5.63
2.22
1.0
1.2
—
—
—
0
0
6
14
4.36
2.16
3.7
1.6
125.50
76.64
umol/l
—
6
14
231
2107
1.59
2.15
8.4
6.5
39.83
39.60
mmol/mol
0.13
217
1986
26
149
1.82
2.03
2.3
2.5
—
7.30
—
0
11
34
212
1.69
2.00
5.9
6.4
5.09
5.16
kpa
0.22
34
207
18
91
2.05
2.00
3.1
2.5
0.00
0.00
g/l
-0.00
18
84
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
11
4.61
1.95
1.6
1.0
96.60
145.00
%
—
5
11
6
16
3.81
1.94
1.8
1.9
15.02
13.06
umol/l
—
6
16
8
29
2.81
1.80
1.1
1.0
—
—
—
0
0
16
83
1.98
1.68
3.3
2.6
0.00
0.00
g/l
-0.00
16
77
8
32
2.54
1.61
1.4
1.6
—
—
—
0
0
15
78
1.98
1.57
1.7
1.6
—
—
—
0
0
38
261
1.53
1.54
3.3
4.3
2.85
49.67
ug/l
0.95
33
225
16
86
1.91
1.54
3.3
2.5
0.00
0.00
g/l
-0.00
16
77
6
21
2.90
1.51
1.3
1.5
—
—
—
0
0
6
21
2.90
1.51
1.3
1.5
—
—
—
0
0
6
21
2.90
1.51
1.3
1.5
—
—
—
0
0
9
37
2.48
1.49
1.2
1.1
—
—
—
0
0
29
190
1.59
1.44
6.2
6.7
0.57
1.58
mmol/l
0.96
18
140
6
22
2.76
1.44
1.3
1.3
128.00
700.79
u/l
—
6
22
9
40
2.29
1.41
2.1
1.3
—
—
—
0
0
35
241
1.52
1.41
12.1
7.7
—
—
—
0
0
18
105
1.76
1.37
3.1
2.8
1.18
1.39
g/l
0.10
18
93
103
864
1.31
1.32
5.3
5.2
1.92
2.39
ug/l
0.55
93
765
12
62
1.98
1.29
2.6
1.6
176.50
265.24
u/ml
—
6
34
5
18
2.81
1.29
2.2
1.6
664.80
1249.94
mg
—
5
18
5
18
2.81
1.29
1.6
3.4
94.40
103.50
%
—
5
18
6
25
2.43
1.25
2.8
2.8
4.00
9.78
nmol/l
—
6
25
212
1965
1.34
1.25
38.1
21.7
14.07
13.70
%
2.64
207
1946
16
94
1.75
1.20
1.3
1.2
—
—
—
0
0
6
26
2.34
1.19
1.3
1.2
—
—
—
0
0
5
20
2.53
1.15
1.0
1.7
—
—
—
0
0
7
32
2.22
1.09
1.9
3.5
—
18.08
—
0
12
10
52
1.96
1.07
1.9
1.3
—
—
—
0
0
10
52
1.96
1.07
2.3
1.2
—
—
—
0
0
7
34
2.09
1.03
1.0
1.4
0.69
50.59
nmol/l
—
7
34
11
61
1.84
1.00
1.7
1.4
—
—
—
0
0
11
61
1.84
1.00
1.7
1.4
—
—
—
0
0
9
49
1.86
0.99
1.6
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
1.8
—
—
—
0
0
14
85
1.68
0.96
5.5
3.0
1.02
2.76
ratio
—
6
44
0
32
0.00
0.95
0.0
1.9
—
—
—
0
0
6
27
2.25
0.94
1.7
1.6
—
—
—
0
0
59
480
1.29
0.93
1.8
1.8
136735215.00
28261318.55
pmol/l
0.36
49
414
6
28
2.17
0.92
1.2
1.5
5.78
3.23
mg/l
—
6
28
12
71
1.72
0.90
1.3
1.5
—
—
—
0
0
8
42
1.93
0.89
1.6
1.3
—
—
—
0
0
46
364
1.32
0.89
1.4
1.4
1.59
14.86
u/ml
2.38
19
143
8
43
1.89
0.88
7.4
3.5
13.64
8.78
pmol/l
—
8
43
6
30
2.02
0.87
1.2
1.3
—
—
—
0
0
106
931
1.22
0.87
2.2
2.0
1.33
1.37
mmol/l
0.18
96
787
6
31
1.96
0.85
1.3
1.3
—
—
—
0
0
6
31
1.96
0.85
1.8
1.5
—
—
—
0
0
80
684
1.24
0.84
3.9
4.3
0.00
0.00
estimate
-0.00
19
240
10
58
1.75
0.80
2.3
1.8
1.98
4.33
iu/l
—
5
22
79
678
1.23
0.80
4.5
4.4
25.27
21.83
%
0.74
35
327
0
24
0.00
0.79
0.0
1.7
—
58.01
—
0
24
6
33
1.84
0.79
1.5
1.8
93.65
66.25
ug/l
—
6
27
10
59
1.72
0.77
1.3
1.3
—
11.54
—
0
7
5
24
2.10
0.75
1.4
1.3
—
—
—
0
0
5
24
2.10
0.75
1.0
1.2
—
—
—
0
0
5
25
2.02
0.73
1.4
1.2
—
—
—
0
0
5
25
2.02
0.73
1.4
1.2
—
—
—
0
0
5
25
2.02
0.73
1.6
1.6
0.77
0.28
nmol/l
—
5
16
5
25
2.02
0.73
1.4
1.2
—
—
—
0
0
11
68
1.64
0.73
1.2
1.4
—
—
—
0
0
5
26
1.94
0.71
1.6
1.6
—
—
—
0
0
9
58
1.57
0.70
1.3
1.3
—
—
—
0
0
104
929
1.19
0.70
4.2
4.2
0.00
0.01
estimate
0.80
18
224
9
59
1.54
0.69
1.1
1.3
—
1.04
—
0
5
11
70
1.60
0.66
1.3
2.5
19675.60
5511.71
u/l
—
5
30
10
63
1.61
0.62
1.2
1.2
—
—
—
0
0
11
76
1.47
0.49
4.3
3.5
0.80
2.24
index
—
5
49
7
46
1.54
0.48
1.0
1.7
—
—
—
0
0
24
191
1.28
0.48
1.7
1.5
—
—
—
0
0
15
113
1.35
0.43
1.4
1.3
—
—
—
0
0
8
58
1.39
0.42
1.0
1.6
—
—
—
0
0
12
88
1.38
0.40
2.6
2.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
11
80
1.39
0.39
1.4
1.1
—
—
—
0
0
11
80
1.39
0.39
1.4
1.1
—
—
—
0
0
8
115
0.69
0.38
2.1
2.3
—
—
—
0
0
11
81
1.37
0.37
1.5
1.7
—
—
—
0
0
30
255
1.20
0.36
1.7
1.5
—
—
—
0
0
5
78
0.63
0.36
1.0
1.2
1.34
1.51
g/l
—
5
78
16
199
0.79
0.34
1.4
2.1
3.05
3.52
ratio
0.53
11
163
7
99
0.70
0.31
1.9
2.1
—
—
—
0
0
19
157
1.23
0.30
1.1
1.2
119.20
442.03
u/ml
1.01
19
146
8
62
1.30
0.28
1.5
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
104.02
—
0
10
0
12
0.00
0.21
0.0
3.7
—
4.63
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
3.7
—
9.88
—
0
12
18
155
1.17
0.20
1.3
1.2
133.53
113.04
u/ml
—
10
60
0
14
0.00
0.20
0.0
2.8
—
3.46
—
0
5
6
50
1.20
0.20
1.0
1.2
—
14.87
—
0
7
15
129
1.17
0.17
1.1
1.0
—
—
—
0
0
5
66
0.75
0.17
1.2
1.1
—
3.94
—
0
5
6
80
0.74
0.15
1.7
1.5
—
—
—
0
0
9
80
1.13
0.15
1.0
1.4
—
—
—
0
0
27
249
1.09
0.12
2.3
3.4
—
—
—
0
0
42
396
1.07
0.12
1.4
1.7
—
—
—
0
0
25
230
1.10
0.12
2.0
2.1
—
—
—
0
0
13
145
0.89
0.09
1.3
1.9
2.52
3.58
mmol/l
—
8
110
28
262
1.08
0.09
5.7
4.5
34.36
31.35
%
0.65
22
159
7
80
0.87
0.07
2.0
1.2
0.83
0.90
g/l
—
7
80
51
524
0.97
0.05
3.1
3.0
0.67
0.82
ug/l
0.60
39
332
41
402
1.02
0.01
1.5
1.3
83.43
30.88
iu/ml
—
10
139
21
213
0.98
0.00
2.0
2.0
—
—
—
0
0
69
685
1.01
0.00
4.0
3.5
0.00
0.12
estimate
0.50
19
217
0
5
0.00
-0.00
0.0
1.4
—
0.74
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_OTORRHAGIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHAGIA | 1.65 [1.23, 2.22] | 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.45 |
During the follow-up period (1.1.1998 — 31.12.2019), 153 out of 677 females with H8_OTORRHAGIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHAGIA | 2.165 [1.52, 3.07] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 847 males with H8_OTORRHAGIA died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTORRHAGIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.191% | 0.416% |
| 5 | 0.975% | 2.488% |
| 10 | 2.277% | 5.739% |
| 15 | 4.61% | 10.897% |
| 20 | 8.497% | 17.972% |
Relationships between endpoints
↥Index endpoint: H8_OTORRHAGIA – Otorrhagia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data