No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
377 |
4. Check minimum number of eventsNone |
377 |
5. Include endpointsNone |
377 |
6. Filter based on genotype QC (FinnGen only) |
334 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
- Parent code in ICD-10
- H70
- Name in latin
- Mastoiditis acuta
Similar endpoints
↥List of similar endpoints to
Acute mastoiditis
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3448 | 1399 | 2033 |
| Only index persons | 3116 | 1283 | 1833 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.04 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 20.70 | 22.79 | 19.10 |
| Only index persons | 20.06 | 21.89 | 18.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 334 | 177 | 157 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.07 |
| Median age at first event (years) | 25.74 | 30.47 | 20.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 352
- Matched controls
- 3520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
199.6
172
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
147.6
131
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
12.5
90.8
104
114
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
702.9
61.7
59
*
DFF00
NOMESCO Finland
Pure tone audiometry
6.7
42.5
78
144
DC1AD
NOMESCO Finland
Temporalbone CT
122.1
40.7
43
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
32.8
31
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
121.0
31.2
33
*
H66.9
ICD-10 Finland
Otitis media, unspecified
6.6
29.8
52
90
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
+∞
29.6
28
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
37.4
27.0
34
10
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
25.3
24
*
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
24.2
23
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
23.2
22
*
UDC00
NOMESCO Finland
Ear microscopy
5.3
23.0
51
110
H60.9
ICD-10 Finland
Otitis externa, unspecified
4.6
21.7
58
146
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.9
21.2
74
227
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
21.0
20
*
38300
ICD-8 Finland
Mastoiditis without mention of otitis media, Acute
+∞
20.0
19
*
H02AB04
ATC
methylprednisolone; systemic
3.5
19.3
78
263
H60.3
ICD-10 Finland
Other infective otitis externa
8.2
17.6
24
31
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
16.8
16
*
H65.0
ICD-10 Finland
Acute serous otitis media
24.5
16.6
23
10
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
167.1
15.6
16
*
3830A
ICD-9 Finland
Mastoiditis and related conditions, Acute mastoiditis
+∞
14.7
14
*
DC1BD
NOMESCO Finland
Temporal bone extensive CT
+∞
14.7
14
*
H92.0
ICD-10 Finland
Otalgia
4.2
14.5
41
107
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
13.6
13
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
12.6
12
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
12.1
106
532
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
11.5
11
*
H65.2
ICD-10 Finland
Chronic serous otitis media
+∞
11.5
11
*
DCD00
NOMESCO Finland
Myringoplasty
+∞
11.5
11
*
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
11.5
11
*
J01MA02
ATC
ciprofloxacin; systemic
2.2
11.4
145
849
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
44.8
11.0
13
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
10.7
215
1488
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
18.2
9.5
14
8
DEB30
NOMESCO Finland
Radical mastoidectomy
102.7
9.5
10
*
4122
FHL
Tympanostomy (tympanic tube)
102.7
9.5
10
*
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
9.4
9
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
9.4
9
*
J01FF01
ATC
clindamycin; systemic
2.1
9.1
107
597
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
19.2
9.0
13
7
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
8.9
53
219
J01DC02
ATC
cefuroxime; systemic
3.4
8.9
33
104
TDA90
NOMESCO Finland
Removal wax from ear
11.1
8.9
16
15
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.8
8.9
49
195
AA1AD
NOMESCO Finland
CT of head and brain
2.1
8.6
102
570
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
13.2
8.4
14
11
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.5
8.4
56
245
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
8.4
8
*
38204, ,
ICD-8 Finland
+∞
8.4
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
8.3
161
1069
H01
ICPC
Ear pain/earache
2.5
8.0
57
257
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
7.7
125
778
D07AB08
ATC
desonide; topical
2.6
7.5
46
193
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.9
7.5
22
59
H66
ICD-10 Finland
Suppurative and unspecified otitis media
6.5
7.3
18
29
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
7.3
7
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
7.3
7
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
7.1
118
736
S02CA02
ATC
flumetasone and antiinfectives; otic
3.6
7.1
24
71
G51.0
ICD-10 Finland
Bell palsy
6.1
7.0
18
31
N02AX02
ATC
tramadol; systemic, rectal
1.8
7.0
152
1032
J01MA12
ATC
levofloxacin; systemic
2.2
7.0
68
350
J01DB01
ATC
cefalexin; oral
2.2
6.8
299
2527
H02AB06
ATC
prednisolone; systemic
1.8
6.7
170
1204
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
12.6
6.6
11
9
ZXA05
NOMESCO Finland
Left side
2.0
6.5
78
433
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
6.5
46
206
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
11.3
6.3
11
10
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
+∞
6.3
6
*
DCD10
NOMESCO Finland
Tympanoplasty
+∞
6.3
6
*
38202, ,
ICD-8 Finland
+∞
6.3
6
*
WX402
NOMESCO Finland
General anaesthesia
1.9
6.2
86
503
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
47
4.69
8.96
1.6
1.4
—
—
—
0
0
23
63
3.84
7.59
1.2
1.5
798.21
16.90
e6/l
0.64
14
50
23
64
3.78
7.43
1.2
1.6
6220.86
119.67
e6/l
0.47
14
54
26
83
3.30
6.86
2.0
2.5
—
—
—
0
0
73
426
1.90
5.22
2.7
1.8
—
—
—
0
0
33
141
2.48
5.17
2.8
1.5
—
—
—
0
0
23
91
2.63
4.22
1.4
1.3
—
—
—
0
0
121
862
1.62
4.20
2.7
2.2
194.80
194.71
u/l
0.00
114
829
8
10
8.15
4.08
1.3
1.5
—
—
—
0
0
101
696
1.63
3.98
2.7
2.2
2.95
2.81
mg/l
0.13
88
611
26
113
2.40
3.95
1.5
1.6
—
—
—
0
0
41
217
2.01
3.88
1.2
1.3
—
34.42
—
0
21
54
320
1.81
3.65
2.8
1.7
—
—
—
0
0
14
40
3.60
3.65
1.1
1.1
—
—
—
0
0
14
40
3.60
3.65
1.1
1.1
—
—
—
0
0
28
131
2.24
3.62
8.5
3.9
24.05
24.69
mmol/l
0.37
28
131
29
139
2.18
3.55
12.2
11.9
15.89
15.88
%
0.00
29
133
22
94
2.43
3.48
4.8
3.5
24.43
25.08
mmol/l
0.62
22
89
169
1342
1.50
3.44
12.9
7.2
1.21
1.21
mmol/l
0.03
148
1182
8
14
5.82
3.36
1.0
1.2
—
—
—
0
0
252
2182
1.55
3.33
3.7
3.4
—
—
—
0
0
46
272
1.80
3.14
11.1
9.1
0.73
1.11
mmol/l
0.39
40
225
51
311
1.75
3.14
2.9
1.7
—
—
—
0
0
57
359
1.70
3.13
1.9
1.6
985.87
1282.93
nmol/l
1.74
48
292
150
1180
1.47
3.12
8.3
5.2
35.98
36.47
g/l
0.49
141
1130
36
198
1.91
3.07
2.2
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
16
5.09
3.06
1.0
1.3
—
—
—
0
0
94
675
1.54
3.02
4.2
2.2
—
—
—
0
0
92
664
1.52
2.88
2.0
1.8
0.69
1.21
mg/l
2.16
74
518
12
39
3.15
2.80
1.7
1.4
—
—
—
0
0
40
235
1.79
2.80
12.8
9.8
118.30
121.00
g/l
0.44
40
229
14
54
2.66
2.73
1.7
1.6
—
—
—
0
0
45
276
1.72
2.72
12.1
8.9
5.14
5.13
kpa
0.02
45
266
45
276
1.72
2.72
12.1
8.9
13.40
12.43
kpa
0.48
45
268
12
40
3.07
2.72
1.7
1.4
—
—
—
0
0
12
40
3.07
2.72
1.7
1.4
—
—
—
0
0
12
40
3.07
2.72
1.7
1.4
—
—
—
0
0
12
40
3.07
2.72
1.7
1.4
—
—
—
0
0
150
1206
1.42
2.67
2.5
1.9
98.20
96.79
pmol/l
0.11
80
638
43
264
1.72
2.60
3.9
3.2
—
—
—
0
0
64
436
1.57
2.58
4.2
2.5
2.25
2.70
e6/l
0.16
28
193
8
20
4.07
2.58
1.1
1.2
89.25
98.05
pmol/l
—
8
20
152
1233
1.41
2.55
21.6
10.9
1.25
1.17
inr
0.89
129
1045
16
69
2.38
2.52
2.4
2.9
1.67
1.88
index
—
6
41
9
26
3.52
2.50
1.3
1.8
0.01
0.64
mmol/l
—
9
26
17
76
2.30
2.48
1.2
1.4
—
—
—
0
0
55
367
1.59
2.42
9.9
7.1
104.20
104.10
mmol/l
0.05
55
367
312
2901
1.66
2.41
19.0
12.7
86.78
87.01
ml/min/173m2
0.07
290
2661
98
744
1.44
2.35
1.8
1.6
18.97
21.45
nmol/l
1.31
89
649
10
34
3.00
2.30
1.2
1.8
—
—
—
0
0
11
40
2.81
2.29
1.7
1.4
—
—
—
0
0
119
941
1.40
2.26
4.0
3.3
2.35
2.35
mmol/l
0.06
108
874
69
493
1.50
2.24
3.1
2.6
2.46
2.43
mmol/l
0.88
58
441
73
528
1.48
2.24
5.9
3.4
202.76
425.66
ng/l
0.47
54
378
101
779
1.42
2.20
4.6
2.7
0.60
0.50
e6/l
0.11
71
553
9
30
3.05
2.16
1.2
1.9
—
—
—
0
0
7
19
3.74
2.16
1.4
1.3
5.19
1.97
mmol/l
—
7
19
27
153
1.83
2.15
4.8
3.1
0.73
1.55
mmol/l
0.58
22
110
15
69
2.23
2.07
3.2
3.8
1.51
3.25
ratio
—
7
39
13
56
2.37
2.07
1.5
1.7
—
—
—
0
0
158
1324
1.35
2.05
2.7
2.5
74.72
74.88
nmol/l
0.03
144
1224
14
63
2.27
2.03
1.3
1.4
—
—
—
0
0
35
219
1.66
2.00
18.4
8.7
8.60
8.32
mmol/l
0.10
35
212
17
84
2.08
1.99
1.3
1.5
—
—
—
0
0
14
64
2.24
1.97
1.1
1.5
—
—
—
0
0
10
39
2.61
1.95
1.4
1.1
—
—
—
0
0
18
92
2.01
1.93
1.9
2.0
—
—
—
0
0
65
474
1.46
1.91
4.3
2.4
1.28
1.24
e6/l
0.02
30
230
7
22
3.22
1.89
1.1
1.6
83.57
78.00
umol/l
—
7
22
12
53
2.31
1.82
1.2
1.5
—
—
—
0
0
132
1093
1.33
1.81
3.7
3.5
29.14
32.81
u/l
0.99
127
1042
90
707
1.37
1.73
2.0
1.6
—
—
—
0
0
15
75
2.04
1.72
3.7
1.5
—
—
—
0
0
5
13
3.88
1.72
1.2
1.8
—
—
—
0
0
5
13
3.88
1.72
1.2
1.8
—
—
—
0
0
5
13
3.88
1.72
1.2
1.8
—
—
—
0
0
255
2329
1.34
1.70
4.3
4.3
14.55
14.55
pmol/l
0.00
240
2176
8
31
2.62
1.67
1.0
1.0
—
—
—
0
0
7
25
2.84
1.66
1.3
1.1
—
—
—
0
0
158
1355
1.30
1.65
4.4
2.7
—
—
estimate
—
0
0
16
84
1.95
1.62
1.9
1.9
—
—
—
0
0
29
184
1.63
1.60
4.9
3.0
5.00
5.08
kpa
0.23
29
177
23
138
1.71
1.56
1.5
1.7
11.86
5.71
iu/ml
—
5
38
89
710
1.34
1.55
3.7
3.4
989.32
992.45
ng/l
0.00
83
592
16
86
1.90
1.53
1.4
1.6
—
—
—
0
0
125
1048
1.30
1.53
4.9
3.5
44.63
35.40
ng/l
0.14
84
676
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
65
2.04
1.50
3.2
4.1
0.27
0.36
iu/ml
—
8
33
315
2996
1.49
1.49
23.8
13.7
22.71
22.42
mg/l
0.06
276
2429
9
37
2.47
1.49
1.0
1.1
—
—
—
0
0
24
148
1.67
1.48
2.2
1.3
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
5
16
3.15
1.44
1.2
1.8
—
—
—
0
0
5
16
3.15
1.44
1.4
1.7
—
—
—
0
0
5
16
3.15
1.44
1.2
1.8
—
—
—
0
0
5
16
3.15
1.44
1.2
1.8
—
—
—
0
0
5
16
3.15
1.44
1.2
1.8
—
—
—
0
0
195
1740
1.27
1.42
12.4
10.4
4.21
4.01
e9/l
0.59
167
1542
7
29
2.44
1.40
1.0
1.1
—
—
—
0
0
6
23
2.64
1.37
3.5
2.4
—
—
—
0
0
6
23
2.64
1.37
1.2
1.7
—
—
—
0
0
6
23
2.64
1.37
1.2
1.7
—
—
—
0
0
6
23
2.64
1.37
1.2
1.7
—
—
—
0
0
169
1489
1.26
1.35
4.4
3.1
130.27
116.88
ug/l
0.32
157
1425
44
321
1.42
1.32
5.3
4.1
31.89
30.90
%
0.25
38
221
248
2291
1.28
1.30
3.6
3.5
51.96
46.30
u/l
0.29
236
2211
94
774
1.29
1.30
3.6
2.7
353.20
340.14
umol/l
0.66
86
702
113
954
1.27
1.28
4.3
3.3
7.42
8.22
mmol/l
1.00
100
823
8
35
2.31
1.27
1.0
1.1
—
—
—
0
0
6
25
2.42
1.25
1.2
2.1
20.25
23.92
ug/l
—
6
25
5
19
2.65
1.22
1.2
1.2
—
—
—
0
0
5
19
2.65
1.22
1.0
1.0
—
—
—
0
0
96
799
1.28
1.22
1.3
1.3
0.98
1.16
u/ml
0.19
26
218
23
149
1.58
1.20
15.2
6.4
24.12
24.72
mmol/l
0.52
23
142
8
40
2.02
1.12
7.0
5.2
428.25
332.09
umol/l
—
8
32
38
279
1.41
1.12
4.3
2.6
30.91
32.44
u/l
0.07
32
235
240
2228
1.24
1.11
5.5
4.0
10.19
9.87
mm/h
0.17
230
2115
11
59
1.89
1.08
2.3
1.3
—
—
—
0
0
7
33
2.14
1.06
1.0
1.1
—
—
—
0
0
12
70
1.74
0.93
1.2
2.6
0.00
0.00
g/l
-0.00
12
63
13
78
1.69
0.93
2.2
2.4
261.02
293.72
ug/l
0.07
13
73
5
104
0.47
0.90
1.2
1.4
—
—
—
0
0
6
29
2.09
0.89
1.0
1.3
—
—
—
0
0
290
2774
1.26
0.88
5.7
5.1
2.01
1.81
mu/l
0.60
274
2617
6
30
2.02
0.87
1.5
1.1
—
94.40
—
0
5
6
30
2.02
0.87
1.0
1.3
—
—
—
0
0
100
869
1.21
0.85
5.2
4.0
7.73
12.04
mg/mmol
0.55
53
550
6
31
1.95
0.84
1.0
1.3
—
—
—
0
0
6
31
1.95
0.84
1.0
1.3
—
—
—
0
0
175
1602
1.18
0.84
4.1
3.3
0.00
8.97
estimate
0.80
40
338
58
477
1.26
0.82
2.1
2.0
3.58
3.62
ratio
0.09
48
391
99
863
1.20
0.82
3.8
3.4
0.00
0.02
estimate
0.96
37
310
14
90
1.58
0.79
1.2
1.4
274.72
283.19
ug/g
—
6
51
173
1590
1.17
0.77
4.0
3.3
0.00
0.00
estimate
0.50
39
336
239
2259
1.18
0.74
11.2
8.1
79.50
76.29
u/l
0.47
226
2160
7
38
1.86
0.74
1.0
1.2
—
—
—
0
0
12
76
1.60
0.72
1.5
1.3
—
—
—
0
0
72
616
1.21
0.72
1.5
1.3
14.88
28.04
iu/ml
2.06
22
194
15
102
1.49
0.68
1.2
1.4
—
—
—
0
0
19
136
1.42
0.68
5.7
2.7
0.66
0.64
%
0.08
19
136
10
62
1.63
0.65
1.4
1.9
—
—
—
0
0
169
1565
1.15
0.65
8.0
6.8
10.13
11.20
umol/l
0.99
162
1509
7
44
1.60
0.65
1.6
1.5
—
—
—
0
0
5
29
1.73
0.64
4.2
3.7
—
—
—
0
0
5
29
1.73
0.64
1.4
1.2
—
—
—
0
0
174
1617
1.15
0.64
4.1
3.4
0.00
0.00
estimate
-0.00
37
311
60
511
1.21
0.64
1.3
1.5
—
—
—
0
0
19
139
1.39
0.62
5.8
2.7
1.25
1.33
%
0.10
19
139
5
30
1.68
0.61
21.2
10.7
0.61
0.58
mmol/l
—
5
30
326
3188
1.31
0.61
14.5
11.3
27.64
27.82
u/l
0.06
321
3132
0
21
0.00
0.60
0.0
9.7
—
38.13
—
0
8
0
21
0.00
0.60
0.0
1.0
—
44.92
—
0
11
0
21
0.00
0.60
0.0
1.0
—
650.55
—
0
11
65
563
1.19
0.58
1.4
1.3
33.56
10.49
u/ml
0.81
24
235
6
36
1.68
0.57
1.0
1.2
—
—
—
0
0
337
3315
1.39
0.56
31.8
20.7
90.58
90.65
fl
0.10
337
3293
79
699
1.17
0.56
3.4
3.5
1.02
1.02
kg/l
0.24
53
461
337
3317
1.37
0.53
32.5
21.2
53.17
41.15
%
0.48
337
3290
337
3317
1.37
0.53
31.9
20.8
4.53
4.58
e12/l
0.85
331
3255
42
496
0.83
0.52
1.4
1.8
1.38
1.45
%
0.25
34
443
106
964
1.14
0.52
4.2
2.7
52.22
59.85
u/l
0.81
98
913
337
3318
1.37
0.52
32.2
20.9
136.14
137.94
g/l
1.32
337
3295
7
45
1.57
0.49
1.3
1.5
—
—
—
0
0
66
588
1.15
0.44
2.4
2.7
0.72
0.73
ug/l
0.04
32
313
5
31
1.62
0.43
2.0
1.4
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
u/ml
—
0
0
136
1273
1.11
0.41
1.9
2.0
1.44
1.42
mmol/l
0.14
117
1107
8
60
1.34
0.40
6.9
2.6
9.61
7.25
pmol/l
—
8
60
59
526
1.15
0.39
1.8
1.7
460.08
43196980.71
pmol/l
0.79
51
463
17
133
1.29
0.39
1.6
1.7
—
—
—
0
0
28
234
1.21
0.38
1.2
1.2
151.36
166.77
u/ml
0.06
11
94
12
158
0.75
0.38
1.2
1.1
1.46
1.51
g/l
0.37
12
158
19
154
1.25
0.34
3.3
2.4
1990.40
3527.88
u/l
—
10
51
100
930
1.11
0.34
4.1
4.3
1.45
1.76
ug/l
0.97
90
858
16
127
1.27
0.34
15.1
4.4
1.86
1.53
%
0.45
16
118
26
220
1.20
0.33
1.7
1.4
—
—
—
0
0
47
525
0.88
0.32
2.6
2.2
—
—
—
0
0
81
749
1.11
0.31
3.0
3.8
21.36
21.66
%
0.05
27
303
17
138
1.24
0.31
1.2
1.4
204.63
260.01
miu/ml
—
8
69
7
53
1.33
0.31
1.9
1.6
—
—
—
0
0
13
163
0.79
0.30
1.2
1.1
0.88
0.91
g/l
0.21
13
163
40
358
1.13
0.27
1.9
1.7
3.45
3.53
mmol/l
0.19
31
268
9
77
1.17
0.24
1.9
1.6
—
—
—
0
0
9
77
1.17
0.24
1.8
1.2
—
—
—
0
0
10
78
1.29
0.24
1.3
1.2
—
—
—
0
0
19
222
0.85
0.24
2.2
2.3
—
—
—
0
0
287
2821
1.09
0.24
6.3
5.6
39.39
38.64
mmol/mol
0.61
273
2699
25
218
1.16
0.24
1.2
1.4
15.69
25.15
iu/l
1.25
20
183
130
1243
1.07
0.23
3.4
3.2
0.06
0.02
estimate
0.24
34
281
5
38
1.32
0.23
1.8
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
207.10
—
0
14
9
114
0.78
0.20
1.3
1.2
—
—
—
0
0
293
2889
1.08
0.20
4.4
4.0
1.37
1.31
mmol/l
0.74
281
2728
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
6
51
1.18
0.19
2.0
1.5
—
—
—
0
0
45
485
0.92
0.18
2.4
2.1
—
—
—
0
0
21
186
1.14
0.17
1.1
1.0
—
—
—
0
0
7
63
1.11
0.17
1.0
1.1
—
—
—
0
0
11
92
1.20
0.16
1.4
1.2
—
—
—
0
0
25
227
1.11
0.14
2.6
2.5
0.08
0.16
e6/l
0.85
25
217
26
283
0.91
0.13
5.9
6.7
—
—
—
0
0
289
2867
1.04
0.09
5.4
4.5
5.92
5.87
mmol/l
0.25
272
2696
96
936
1.04
0.08
3.1
2.7
0.03
0.01
estimate
0.33
33
262
6
74
0.81
0.07
1.2
1.2
—
72.74
—
0
9
300
3016
0.96
0.06
5.3
4.8
4.66
4.71
mmol/l
0.43
291
2876
303
3044
0.97
0.05
5.8
5.3
2.78
2.80
mmol/l
0.14
292
2889
12
111
1.08
0.04
1.4
1.5
—
—
—
0
0
26
270
0.96
0.03
2.3
2.3
—
—
—
0
0
10
92
1.09
0.03
1.4
1.2
—
—
—
0
0
300
3010
0.98
0.02
5.1
4.7
1.41
1.44
mmol/l
0.70
287
2852
22
226
0.97
0.00
3.2
2.5
71.00
68.53
ml/min/173m2
—
10
99
17
172
0.99
0.00
1.2
1.6
0.62
0.34
mg/l
—
7
80
11
109
1.01
0.00
1.4
1.4
1.63
1.21
ratio
—
5
73
11
107
1.03
0.00
1.4
1.4
—
—
—
0
0
18
176
1.02
0.00
1.3
1.4
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.4
0.38
0.40
nmol/l
—
7
57
5
59
0.85
-0.00
2.0
1.5
54.76
45.04
ug/l
—
5
59
5
50
1.00
-0.00
3.0
2.4
22.78
6.85
umol/l
—
5
36
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
35.52
—
0
5
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.0
—
0.02
—
0
15
Mortality – FinRegistry
↥Association
Association between endpoint H8_MASTACU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MASTACU | 1.511 [1.14, 2.01] | 0.004 |
| Birth year | 0.996 [0.99, 1.0] | 0.347 |
During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 695 females with H8_MASTACU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MASTACU | 1.681 [1.23, 2.29] | 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 630 males with H8_MASTACU died.
Mortality risk
Mortality risk for people of age
years, who have H8_MASTACU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.291% |
| 5 | 0.85% | 1.9% |
| 10 | 2.049% | 4.692% |
| 15 | 4.027% | 8.837% |
| 20 | 7.316% | 14.976% |
Relationships between endpoints
↥Index endpoint: H8_MASTACU – Acute mastoiditis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data