Other disorders affecting eyelid function

H7_EYELIDFUNC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H02.5
  • Hospital discharge: ICD-9 3744
  • Cause of death: ICD-10 H02.5
  • Cause of death: ICD-9 3744

2 out of 7 registries used, show all original rules.

389

4. Check minimum number of events

None

389

5. Include endpoints

None

389

6. Filter based on genotype QC (FinnGen only)

346

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Aliae morbositates functionem palpebrarum afficientes

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1353 726 623
Only index persons 1292 696 596
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 63.72 62.36 65.24
Only index persons 63.77 62.36 65.41

-FinnGen-

Key figures

All Female Male
Number of individuals 346 186 160
Unadjusted period prevalence (%) 0.07 0.07 0.07
Median age at first event (years) 64.64 61.50 68.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
358
Matched controls
3580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
307.7
351
*
H02.3
ICD-10 Finland
Blepharochalasis
313.8
307.7
191
13
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
1770.6
130.7
119
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
122.0
110
*
H02.4
ICD-10 Finland
Ptosis of eyelid
153.7
80.9
83
7
WX720
NOMESCO Finland
Own respiration
12.7
78.7
86
87
WX704
NOMESCO Finland
Intubation
8.5
63.0
96
148
WX725
NOMESCO Finland
Noninvasive ventilation
8.6
54.0
78
112
WX100
NOMESCO Finland
Conjunctival surface anesthesia
5.8
49.1
115
270
QAJ10
NOMESCO Finland
Browlift
+∞
44.7
42
*
H04.10
ICD-10 Finland
Dry eye syndrome
7.7
44.4
70
110
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.9
42.5
124
347
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
40.7
155
530
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
31.7
30
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
31.7
30
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
316.3
29.2
29
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
7.1
27.6
44
69
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
27.4
26
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
9.1
26.6
34
41
WX110
NOMESCO Finland
Infiltration anesthesia
4.7
26.2
308
2028
F16
ICPC
Eyelid symptom/complaint
6.9
24.1
39
62
WX400
NOMESCO Finland
Inhalation anesthesy
7.0
23.1
37
58
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.9
21.6
192
1024
F29
ICPC
Eye symptom/complaint other
4.0
21.3
70
206
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
20.7
75
236
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.0
20.3
65
187
ZXA10
NOMESCO Finland
Bilateral
3.2
19.9
98
374
SPAT1301
SPAT
No procedures
2.8
19.6
154
761
WX702
NOMESCO Finland
Supraglottic ventilation device
4.7
19.2
48
114
SPAT1153
SPAT
Removal of sutures
2.7
17.7
155
799
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
8.0
17.2
24
32
CD2S4
NOMESCO Finland
Photography of eye
37.0
16.9
21
6
H02.1
ICD-10 Finland
Ectropion of eyelid
+∞
16.8
16
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.0
16.3
51
144
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
7.0
16.0
25
38
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.9
15.9
95
400
H02.8
ICD-10 Finland
Other specified disorders of eyelid
167.0
15.6
16
*
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
4.7
15.4
38
89
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
14.9
112
528
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
14.7
14
*
H02.7
ICD-10 Finland
Other degenerative disorders of eyelid and periocular area
156.1
14.6
15
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
156.1
14.6
15
*
H03BB01
ATC
carbimazole; oral
5.4
14.4
29
57
N03AX12
ATC
[U] gabapentin; oral
2.8
14.1
89
383
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
13.6
13
*
CBJ41
NOMESCO Finland
Shortening of superior tarsal muscle (Müller's muscle)
+∞
13.6
13
*
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
5.4
13.4
27
53
-1, ,
ICPC
4.7
13.2
32
74
H02.2
ICD-10 Finland
Lagophthalmos
+∞
12.6
12
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.3
11.9
141
802
S18
ICPC
Laceration/cut
2.2
11.6
201
1327
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
11.5
11
*
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
11.5
11
*
XQ845
NOMESCO Finland
Dermatoscopy
9.7
11.2
22
24
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.1
11.1
51
183
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.7
11.0
36
104
H25.1
ICD-10 Finland
Senile nuclear cataract
2.2
10.9
125
697
SPAT1263
SPAT
Sampling
2.1
10.9
168
1053
WX402
NOMESCO Finland
General anaesthesia
2.3
10.8
106
555
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
113.2
10.5
11
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
10.5
10
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
10.5
10
*
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
10.5
10
*
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
10.5
10
*
DFF15
NOMESCO Finland
Speech audiometry
3.6
10.4
36
108
UDC00
NOMESCO Finland
Ear microscopy
3.1
10.2
45
158
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.4
10.1
38
121
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.9
10.0
51
194
WX872
NOMESCO Finland
Intensive care
3.7
9.7
32
93
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
9.0
64
288
H01.0
ICD-10 Finland
Blepharitis
3.8
8.9
28
79
K76
ICPC
Ischaemic heart dis without angina
5.0
8.7
19
40
TQW40, ,
SPAT
2.6
8.6
52
216
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.1
8.6
24
62
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
28.3
8.5
11
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
7.0
8.5
20
30
KMAK, ,
NOMESCO Finland
1.9
8.4
183
1262
H062, E050,
ICD-10 Finland
+∞
8.4
8
*
A02BC03
ATC
lansoprazole; oral
2.0
8.3
120
720
SAA03
NOMESCO Finland
Extended examination of mouth
1.9
8.2
148
956
L12
ICPC
Hand/finger symptom/complaint
2.2
8.2
76
384
T86
ICPC
Hypothyroidism/myxoedema
4.1
8.0
22
56
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
7.9
121
738
D06
ICPC
Abdominal pain localized other
2.7
7.8
43
170
R44
ICPC
Respiratory, Preventive immunization/medic
9.2
7.6
15
17
G44.2
ICD-10 Finland
Tension-type headache
2.3
7.6
62
297
R09
ICPC
Sinus symptom/complaint
2.8
7.5
38
144
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
7.5
68
340
ZXA05
NOMESCO Finland
Left side
2.0
7.5
99
572
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
7.3
7
*
3744A
ICD-9 Finland
Other disorders of eyelids, Other disorders affecting eyelid function
+∞
7.3
7
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
16.1
7.3
11
7
A78
ICPC
Infectious disease other/NOS
7.6
7.3
16
22
WX002
NOMESCO Finland
Sedation and analgesia
2.1
7.3
78
417
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
6.8
7.2
17
26
DFF00
NOMESCO Finland
Pure tone audiometry
2.4
7.2
51
229
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.0
7.1
99
582
R1100, ,
SPAT
7.2
7.1
16
23
R07.0
ICD-10 Finland
Pain in throat
3.1
7.0
30
103
BAA60
NOMESCO Finland
Total thyroidectomy
4.5
7.0
17
39
SPAT1260
SPAT
Consultation of another employee
2.1
6.9
74
394
SPAT1097
SPAT
Recording of ECG
2.2
6.9
65
329
R51.80
ICD-10 Finland
Headache
2.2
6.9
66
337
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
6.8
112
694
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
6.8
125
804
H57.1
ICD-10 Finland
Ocular pain
3.9
6.7
20
54
DAX08
NOMESCO Finland
Fitting of hearing aid
2.8
6.7
34
129
EB1VA, ,
NOMESCO Finland
2.1
6.6
73
394
L17
ICPC
Foot/toe symptom/complaint
1.8
6.6
124
802
G51.0
ICD-10 Finland
Bell palsy
5.9
6.5
17
30
M79.6
ICD-10 Finland
Pain in limb
1.8
6.5
163
1147
CEW99
NOMESCO Finland
Other operation on extraocular muscle
71.1
6.4
7
*
M03BX02
ATC
tizanidine; oral
1.8
6.4
227
1761
SCC01
NOMESCO Finland
Fluoride application or other respective small prophylactic procedure
5.4
6.4
18
35
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.3
99
603
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.3
116
743
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
+∞
6.3
6
*
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
6.3
6
*
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
6.3
6
*
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.1
6.2
61
314
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.9
6.2
30
111
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.0
6.1
28
100
H02AB06
ATC
prednisolone; systemic
1.7
6.1
178
1300
A02BC01
ATC
omeprazole; systemic
1.8
6.1
106
666
104
Kela drug reimbursment
Thyroid insufficiency
2.7
6.1
34
136
C01DA14
ATC
isosorbide mononitrate; oral
2.1
6.1
61
317

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
86
10.41
59.33
6.5
7.7
1.24
1.30
mmol/l
0.24
67
77
152
615
3.56
29.61
5.3
4.0
242.88
380.64
ng/l
0.42
121
493
153
754
2.80
19.53
4.3
4.1
1.02
1.02
kg/l
0.66
121
504
38
75
5.55
18.81
5.2
1.9
6.18
4.00
iu/l
0.50
26
28
61
201
3.45
15.47
6.9
4.7
—
—
—
0
0
94
399
2.84
15.45
8.1
7.5
7.41
7.41
ph
0.05
68
239
323
2530
3.83
14.32
28.5
21.0
334.03
331.94
g/l
4.09
323
2519
91
398
2.72
14.00
8.0
7.4
1.97
0.87
mmol/l
2.76
75
333
295
2274
2.69
11.89
5.0
4.3
—
16836.17
—
0
6
81
361
2.61
11.84
8.2
7.6
96.43
95.38
%
1.47
76
350
213
1441
2.18
11.53
5.5
4.9
35.98
35.52
g/l
0.65
203
1364
173
1101
2.11
10.73
3.7
3.1
29.24
33.16
u/l
0.56
165
1043
157
972
2.10
10.39
3.8
6.6
—
—
—
0
0
81
1449
0.43
10.24
9.2
11.4
0.00
0.00
e9/l
0.62
60
1189
21
43
5.13
9.91
2.4
1.7
12.33
10.92
mmol/l
1.15
21
43
159
1015
2.02
9.45
4.0
4.0
7.40
7.40
ph
0.54
133
713
229
1673
2.02
9.16
9.2
7.2
1.21
1.21
mmol/l
0.16
217
1446
17
17
10.44
9.12
1.4
1.8
—
—
—
0
0
174
1161
1.97
8.99
3.6
3.4
7.95
7.68
mmol/l
0.37
158
975
172
1146
1.96
8.90
3.8
4.2
3.68
7.46
mg/mmol
2.11
110
710
193
1345
1.94
8.67
2.5
1.9
1.37
1.34
mmol/l
0.21
186
1122
168
1118
1.95
8.65
3.5
3.4
21.11
46.19
mg/l
2.82
108
722
295
2395
2.32
8.58
5.9
4.1
14.75
14.84
pmol/l
0.26
285
2171
210
1510
1.95
8.54
7.2
6.2
1.20
1.21
mmol/l
1.12
205
1392
68
353
2.14
6.80
1.7
1.5
—
—
—
0
0
208
1558
1.80
6.78
10.8
13.2
1.21
1.23
inr
0.17
190
1283
196
1453
1.77
6.52
2.3
2.1
89.93
96.44
pmol/l
1.04
91
750
336
2986
3.04
6.50
7.3
6.6
39.05
39.56
mmol/mol
0.69
326
2802
256
2059
1.85
6.41
5.5
4.5
—
275.92
—
0
38
327
2873
2.60
6.37
7.2
5.1
1.93
1.95
mu/l
0.09
321
2619
151
1046
1.77
6.29
4.6
5.7
—
—
—
0
0
38
158
2.57
6.28
1.3
1.9
—
—
—
0
0
139
947
1.76
6.09
2.8
3.3
0.17
0.00
estimate
0.46
12
292
241
1918
1.78
6.08
6.7
4.7
6.69
6.74
mmol/l
0.12
230
1823
349
3246
3.99
5.98
13.5
12.3
25.69
25.88
u/l
0.09
344
3147
88
535
1.86
5.56
1.5
1.7
1028.64
1243.32
nmol/l
1.83
77
408
218
1735
1.66
5.03
4.1
3.9
0.00
0.02
estimate
0.79
15
336
196
1521
1.64
4.98
3.1
2.8
—
—
estimate
—
0
0
216
1719
1.65
4.95
4.0
3.9
0.00
0.00
estimate
-0.00
16
369
174
1313
1.63
4.93
3.7
3.8
0.36
0.02
estimate
0.44
11
304
288
2477
1.83
4.93
7.8
8.4
72.14
80.64
u/l
4.79
279
2338
342
3142
2.98
4.77
20.7
14.5
—
—
—
0
0
12
22
5.60
4.64
3.7
2.4
13.41
13.14
%
0.39
12
22
332
3017
2.38
4.58
5.9
5.3
5.86
6.00
mmol/l
1.43
323
2771
34
158
2.27
4.44
1.3
1.1
—
—
—
0
0
209
1677
1.59
4.40
4.9
6.2
0.20
0.20
e9/l
0.04
197
1460
212
1710
1.59
4.34
3.9
3.8
0.00
0.00
estimate
-0.00
16
354
203
1621
1.58
4.34
4.8
5.9
0.61
0.59
e9/l
0.62
190
1379
8
266
0.28
4.33
1.9
3.6
—
—
—
0
0
334
3057
2.38
4.28
17.5
16.1
25.60
23.90
mg/l
0.45
286
2517
139
1019
1.60
4.28
2.5
2.1
224.40
268.62
u/l
0.17
134
967
203
1628
1.57
4.21
4.8
5.9
0.04
0.04
e9/l
0.11
190
1387
350
3318
3.45
4.18
29.6
25.0
134.88
134.98
g/l
0.04
350
3283
35
169
2.19
4.18
6.6
3.6
4.27
4.52
pmol/l
0.94
35
151
350
3316
3.48
4.18
30.0
25.2
39.99
40.33
%
0.53
350
3278
350
3316
3.48
4.18
29.2
24.7
30.34
30.40
pg
0.31
350
3281
350
3315
3.50
4.17
29.2
24.8
90.74
91.42
fl
2.36
350
3280
15
47
3.29
4.10
1.1
1.1
—
—
—
0
0
205
1655
1.56
4.07
5.0
6.0
1.88
1.97
e9/l
0.52
194
1456
62
968
0.57
4.07
2.9
3.0
0.40
0.49
e6/l
0.24
39
705
173
1355
1.54
3.88
3.5
3.4
6.20
6.17
ph
0.17
115
769
131
970
1.55
3.76
4.3
3.1
—
—
—
0
0
332
3064
2.15
3.61
5.7
5.3
4.51
4.60
mmol/l
0.83
327
2842
336
3118
2.26
3.55
7.1
6.1
2.54
2.67
mmol/l
1.91
330
2881
115
838
1.55
3.51
2.4
2.2
1.90
3.01
mg/l
8.17
110
739
91
1251
0.63
3.44
3.4
3.9
58.40
90.80
e6/l
0.49
66
893
44
710
0.57
3.15
2.0
3.1
0.78
0.78
ug/l
0.00
23
464
31
161
2.01
3.10
2.2
2.4
—
—
—
0
0
18
77
2.41
2.87
1.8
1.7
—
—
—
0
0
328
3056
1.87
2.81
5.4
5.2
1.42
1.47
mmol/l
1.66
322
2817
10
265
0.36
2.79
1.8
3.8
1.24
1.23
mmol/l
—
10
227
5
6
8.43
2.75
8.6
6.0
4.80
4.90
kpa
—
5
6
42
254
1.74
2.67
3.5
3.7
73.60
78.75
ng/l
0.13
42
221
127
999
1.42
2.51
1.6
1.7
21.56
20.65
nmol/l
0.31
121
834
85
1124
0.68
2.47
2.9
3.2
65.19
57.15
e6/l
0.09
62
858
80
1066
0.68
2.41
2.0
2.5
—
—
—
0
0
211
1818
1.39
2.41
7.1
10.1
3.93
4.12
e9/l
0.67
200
1584
5
155
0.31
2.34
13.8
3.8
—
—
—
0
0
9
29
3.16
2.24
1.1
1.3
18.86
37.26
ng/l
—
9
29
14
291
0.46
2.22
4.3
5.1
0.20
0.05
%
—
5
84
99
1253
0.71
2.20
2.2
2.1
—
—
—
0
0
10
233
0.41
2.12
8.6
3.8
5.16
5.19
kpa
—
10
228
10
230
0.42
2.06
8.5
3.7
7.42
7.42
ph
—
10
193
202
1758
1.34
2.01
5.5
6.8
12.33
11.41
umol/l
0.54
196
1679
168
1424
1.34
2.00
2.8
2.5
80.30
77.49
nmol/l
0.67
161
1275
36
545
0.62
1.97
2.6
2.9
10.71
2.11
e6/l
—
10
264
15
290
0.50
1.95
2.3
4.6
7.35
7.35
ph
—
10
201
98
1222
0.73
1.94
2.7
3.3
—
—
—
0
0
74
552
1.43
1.92
1.3
1.3
22.85
14.63
u/ml
0.24
20
215
12
52
2.35
1.89
1.3
1.4
—
—
—
0
0
0
54
0.00
1.87
0.0
2.2
—
0.88
—
0
39
89
693
1.38
1.81
1.7
1.8
429.72
428.57
pmol/l
0.02
81
580
7
23
3.08
1.81
1.7
3.3
507.57
1004.74
mg
—
7
23
83
1052
0.73
1.80
3.4
3.3
1299.66
1267.14
ng/l
0.03
74
902
16
293
0.52
1.77
1.6
1.4
—
—
—
0
0
15
279
0.52
1.75
4.0
4.8
0.40
0.14
%
—
5
84
0
47
0.00
1.71
0.0
2.9
—
4.52
—
0
47
0
48
0.00
1.71
0.0
2.0
—
32.67
—
0
48
37
246
1.56
1.68
1.2
1.2
—
—
—
0
0
234
2111
1.31
1.66
3.5
3.2
45.66
50.19
u/l
0.46
229
1983
11
49
2.28
1.65
1.3
1.4
—
—
—
0
0
11
49
2.28
1.65
1.3
1.4
—
—
—
0
0
11
49
2.28
1.65
1.3
1.4
—
—
—
0
0
11
49
2.28
1.65
1.3
1.4
—
—
—
0
0
78
604
1.37
1.63
1.4
1.3
41.38
35.50
iu/ml
0.09
32
190
310
2928
1.44
1.55
4.0
4.5
1.32
1.29
mmol/l
0.38
299
2687
48
652
0.70
1.55
2.4
3.1
2.43
2.46
mmol/l
0.86
42
586
5
15
3.36
1.53
1.0
1.3
5.20
9.27
mm/h
—
5
15
24
149
1.65
1.45
1.3
1.9
1.44
1.49
g/l
0.16
24
136
28
181
1.59
1.45
1.3
1.2
207.32
138.43
u/ml
0.35
12
76
19
311
0.59
1.45
1.4
2.3
0.21
0.21
g/l
0.03
19
293
5
17
2.97
1.36
1.2
1.6
33.00
51.56
ug/l
—
5
17
50
371
1.40
1.36
2.0
1.6
—
—
—
0
0
6
131
0.45
1.31
1.8
2.9
23.67
24.97
mmol/l
—
6
131
91
745
1.30
1.31
1.6
1.7
0.86
1.32
mg/l
1.57
74
584
60
760
0.75
1.26
2.4
2.6
4.45
5.36
e6/l
0.32
51
695
12
63
1.94
1.24
1.1
1.1
—
—
—
0
0
61
476
1.34
1.23
6.0
6.2
104.08
103.96
mmol/l
0.07
61
476
35
248
1.46
1.22
1.8
1.4
—
—
—
0
0
58
452
1.34
1.18
4.9
5.2
1.05
1.05
mmol/l
0.01
58
415
0
35
0.00
1.15
0.0
1.2
—
—
—
0
0
16
256
0.61
1.14
4.9
3.5
—
—
—
0
0
42
313
1.39
1.13
1.6
2.8
61.87
71.12
e9/l
1.62
36
236
8
40
2.02
1.12
1.1
1.1
—
—
—
0
0
8
41
1.97
1.09
1.1
1.0
—
—
—
0
0
53
413
1.33
1.09
1.4
1.4
—
—
—
0
0
114
1311
0.81
1.08
3.7
3.9
42.68
80.88
ng/l
0.44
63
983
20
298
0.65
1.06
4.0
4.6
0.80
0.90
%
—
10
103
19
280
0.66
0.97
4.0
2.5
4.87
6.48
ug/l
0.23
19
260
58
467
1.29
0.95
2.2
1.9
—
—
—
0
0
84
978
0.82
0.88
3.9
4.0
0.00
0.02
estimate
0.78
14
333
108
943
1.21
0.87
3.4
4.1
—
—
—
0
0
20
280
0.70
0.80
3.0
4.7
0.91
0.49
%
0.57
11
92
53
433
1.26
0.79
1.1
1.4
300.00
516.70
titre
1.16
14
109
6
33
1.83
0.79
1.0
1.1
—
—
—
0
0
6
33
1.83
0.79
1.0
1.2
—
—
—
0
0
5
96
0.51
0.79
7.0
3.1
8.06
7.95
kpa
—
5
96
63
745
0.81
0.76
3.3
4.9
—
—
—
0
0
6
34
1.78
0.76
2.8
1.4
8.90
10.94
%
—
6
34
18
124
1.48
0.76
1.8
1.5
7.95
9.70
u/ml
—
8
22
12
75
1.62
0.76
4.9
4.8
—
—
—
0
0
97
850
1.19
0.75
2.8
2.9
348.24
344.10
umol/l
0.14
87
747
54
648
0.80
0.75
2.0
2.8
541.67
524.14
mosm/kgh2o
0.28
43
567
9
57
1.59
0.71
1.1
1.1
—
—
—
0
0
5
95
0.52
0.67
9.8
10.7
—
—
—
0
0
13
86
1.53
0.67
6.2
2.5
60.34
61.65
%
0.08
13
86
83
726
1.19
0.66
1.3
1.3
0.59
1.49
u/ml
1.80
15
201
25
190
1.34
0.64
2.5
1.6
—
—
—
0
0
36
442
0.79
0.62
1.1
1.3
—
—
—
0
0
5
30
1.68
0.61
3.6
3.2
—
—
—
0
0
25
192
1.32
0.61
1.4
1.2
442.97
301.27
u/ml
0.20
25
179
31
386
0.78
0.61
1.1
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
4.02
—
0
6
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
54
459
1.21
0.59
1.9
1.7
—
—
—
0
0
8
53
1.52
0.59
2.1
3.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.7
—
37.28
—
0
23
87
773
1.17
0.58
3.7
3.7
—
0.22
—
0
9
18
134
1.36
0.54
1.7
1.8
—
—
—
0
0
6
97
0.61
0.53
1.0
1.2
0.81
0.87
g/l
—
6
97
10
68
1.48
0.47
1.1
1.6
—
—
—
0
0
18
229
0.77
0.44
1.2
1.6
0.86
1.39
g/l
1.72
18
213
6
93
0.64
0.43
1.0
1.2
1.47
1.56
g/l
—
6
93
8
58
1.39
0.42
1.3
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
2.8
—
16.87
—
0
17
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
7
103
0.67
0.40
2.4
2.8
1.23
1.46
mg/l
—
7
91
9
67
1.35
0.38
1.1
1.1
—
—
—
0
0
13
98
1.34
0.38
1.7
1.9
49.62
41.24
nmol/l
0.57
13
93
13
169
0.76
0.38
1.0
1.3
—
—
—
0
0
5
37
1.36
0.37
1.0
1.2
—
—
—
0
0
5
37
1.36
0.37
1.8
2.6
—
—
—
0
0
36
415
0.85
0.36
1.4
1.3
—
—
—
0
0
36
412
0.86
0.34
1.4
1.5
—
—
—
0
0
17
209
0.80
0.33
1.2
1.4
—
—
—
0
0
24
284
0.83
0.33
2.7
2.9
65.67
66.78
g/l
0.44
24
262
7
53
1.33
0.31
1.7
1.9
—
—
—
0
0
7
55
1.28
0.30
1.0
1.0
—
—
—
0
0
7
56
1.25
0.29
1.0
1.8
—
—
—
0
0
10
77
1.31
0.26
1.1
1.6
—
—
—
0
0
10
77
1.31
0.26
2.3
1.5
263.90
279.38
mu/l
—
10
72
32
283
1.14
0.25
5.3
6.9
11.43
9.96
mmol/l
0.52
32
267
27
307
0.87
0.25
1.6
2.6
23.48
32.63
u/l
2.80
21
260
60
648
0.91
0.24
1.3
1.4
2.24
2.65
g/l
1.34
36
392
13
106
1.23
0.23
1.1
1.1
—
—
—
0
0
10
79
1.27
0.22
1.1
1.6
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
4.8
—
51.18
—
0
11
0
11
0.00
0.21
0.0
1.4
—
513.40
—
0
5
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
27.82
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
19
164
1.17
0.21
1.7
2.5
40.36
74.31
u/ml
0.46
19
158
10
80
1.26
0.20
1.1
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
69.34
—
0
5
33
363
0.90
0.19
4.9
4.7
2.90
37.18
ug/l
0.93
28
302
10
81
1.24
0.19
1.1
1.6
—
—
—
0
0
10
81
1.24
0.19
1.1
1.6
—
—
—
0
0
26
288
0.90
0.17
11.2
7.8
—
—
—
0
0
7
63
1.11
0.17
3.1
3.0
0.83
0.75
nmol/l
—
7
51
5
67
0.74
0.17
1.4
1.6
—
—
—
0
0
13
111
1.18
0.16
1.1
1.3
—
—
—
0
0
22
197
1.12
0.15
3.6
2.8
25.55
24.48
mmol/l
1.30
22
197
9
78
1.16
0.15
1.4
1.9
145.56
238.07
pmol/l
—
9
70
12
140
0.85
0.15
1.2
1.1
—
—
—
0
0
36
334
1.09
0.14
1.6
1.5
—
—
—
0
0
16
141
1.14
0.14
1.5
3.8
27.62
8543.83
u/ml
0.66
16
123
19
209
0.90
0.11
1.9
1.9
3.02
3.49
mmol/l
0.60
12
161
10
86
1.17
0.11
1.0
1.1
—
—
—
0
0
19
208
0.91
0.10
1.2
1.2
—
—
—
0
0
40
378
1.07
0.10
1.8
2.3
238.35
137.63
ug/g
0.27
34
306
5
45
1.11
0.10
1.2
1.9
—
—
—
0
0
6
58
1.04
0.08
1.5
1.3
—
—
—
0
0
7
83
0.84
0.07
1.0
1.2
—
—
—
0
0
13
118
1.11
0.07
2.7
2.2
8.95
10.69
g/l
1.35
13
106
28
265
1.06
0.07
1.5
1.4
—
—
—
0
0
10
90
1.11
0.05
1.3
1.3
—
—
—
0
0
13
140
0.93
0.04
1.2
1.6
0.37
0.38
mg/l
—
8
61
28
269
1.04
0.04
3.4
2.4
6.29
6.06
ph
0.58
14
181
29
279
1.04
0.04
2.0
2.6
10.65
10.73
g/l
0.03
29
257
22
229
0.96
0.03
2.5
2.7
—
—
—
0
0
12
127
0.94
0.01
1.3
1.3
—
—
—
0
0
112
1113
1.01
0.01
2.7
3.6
2.33
2.35
mmol/l
1.48
104
1007
11
113
0.97
0.00
2.8
2.7
—
—
—
0
0
35
347
1.01
0.00
4.5
3.3
7.39
7.38
ph
0.10
17
194
13
135
0.96
0.00
1.6
2.3
3.76
7.40
iu/ml
—
5
40
90
897
1.00
0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
9.06
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
0.00
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
17.50
—
0
5
0
8
0.00
-0.00
0.0
2.0
—
0.61
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
23.18
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
27.63
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
76.80
—
0
5
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
30
300
1.00
-0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
-0.00
1.4
1.3
15.78
8.88
u/l
—
7
61
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
33.25
—
0
8
6
63
0.95
-0.00
1.3
1.3
66.00
58.38
mmol/l
—
6
56
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
36.88
—
0
7

Mortality – FinRegistry

Association

Association between endpoint H7_EYELIDFUNC and mortality.

Females

Parameter HR [95% CI] p-value
H7_EYELIDFUNC 0.941 [0.68, 1.3] 0.712
Birth year 0.992 [0.98, 1.0] 0.079

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 514 females with H7_EYELIDFUNC died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_EYELIDFUNC.

N-year risk Females Males
1 0.081% No data
5 0.507% No data
10 1.238% No data
15 2.395% No data
20 4.239% No data

Relationships between endpoints

Index endpoint: H7_EYELIDFUNC – Other disorders affecting eyelid function

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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