Sequelae of tuberculosis, including avohilmo

AB1_SEQULAE_TUBERCU_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 B90
  • Hospital discharge: ICD-10 B90
  • Hospital discharge: ICD-9 137
  • Hospital discharge: ICD-8 01[9]
  • Cause of death: ICD-10 B90
  • Cause of death: ICD-9 137
  • Cause of death: ICD-8 01[9]

3 out of 7 registries used, show all original rules.

874

4. Check minimum number of events

None

874

5. Include endpoints

None

874

6. Filter based on genotype QC (FinnGen only)

758

Control definitions (FinnGen only)

Control exclude
AB1_SEQULEAE_OF_INFECTIONS_AND_PARASITES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 758 288 470
Unadjusted period prevalence (%) 0.17 0.10 0.22
Median age at first event (years) 66.77 64.26 68.30

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
788
Matched controls
7880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
+∞
307.7
535
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
59.1
97.6
55
10
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.1
77.7
324
1157
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
+∞
75.2
71
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
37.8
69.0
43
12
J96.1
ICD-10 Finland
Chronic respiratory failure
7.9
63.5
92
129
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.3
55.7
170
473
1370X
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,MUU JÄLKITILA]
+∞
53.8
51
*
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
+∞
52.7
50
*
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
+∞
52.7
50
*
J47
ICD-10 Finland
Bronchiectasis
8.9
52.1
67
81
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.8
51.4
195
631
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.4
51.0
251
960
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.5
50.9
229
828
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
21.5
49.0
37
18
R03BB01
ATC
ipratropium bromide; inhalant
4.0
44.3
142
406
R03DA04
ATC
theophylline; systemic, rectal
3.6
43.0
166
539
R03AC02
ATC
salbutamol; inhalant
2.8
42.4
468
2719
B90.2
ICD-10 Finland
Sequelae of tuberculosis of bones and joints
+∞
41.0
39
*
R03BB04
ATC
tiotropium bromide; inhalant
3.2
40.5
195
725
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.3
36.7
161
563
J45.1
ICD-10 Finland
Nonallergic asthma
4.0
34.2
107
298
J45.9
ICD-10 Finland
Asthma, unspecified
2.8
33.4
213
917
R03AC12
ATC
salmeterol; inhalant
3.8
32.6
109
318
R03BA01
ATC
beclometasone; inhalant
2.9
30.7
173
694
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
30.4
188
793
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
28.9
398
2416
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
66.6
28.1
32
5
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
6.8
27.5
44
68
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.3
26.1
108
361
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
5.7
25.5
49
91
R03BA05
ATC
fluticasone; inhalant
2.6
25.1
174
771
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.1
24.6
70
181
H02AB06
ATC
prednisolone; systemic
2.1
23.2
423
2789
R04.2
ICD-10 Finland
Haemoptysis
4.0
22.9
69
186
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
7.3
20.9
31
44
R03BA02
ATC
budesonide; inhalant
2.4
20.0
169
814
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.8
19.8
106
408
J45.8
ICD-10 Finland
Mixed asthma
4.7
19.6
46
102
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.4
19.4
74
234
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
5.5
18.4
36
68
R03AC13
ATC
formoterol; inhalant
3.2
17.5
72
238
01904
ICD-8 Finland
Late effects of tuberculosis, Adhaesiones pleurae
+∞
16.7
16
*
H02AB04
ATC
methylprednisolone; systemic
2.3
15.8
141
689
TGC00
NOMESCO Finland
Bronchial lavation
4.6
15.8
38
86
J01AA02
ATC
doxycycline; systemic
2.0
15.7
593
4748
01909
ICD-8 Finland
Late effects of tuberculosis, Sequelae NUD o tuberculosis organorum respirationis
+∞
15.7
15
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.0
14.8
70
251
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
21.5
14.7
21
10
B90.8
ICD-10 Finland
Sequelae of tuberculosis of other organs
+∞
14.6
14
*
R03AK07
ATC
formoterol and budesonide; inhalant
2.2
14.2
138
697
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
13.8
180
1015
R03DC03
ATC
montelukast; oral
2.3
13.7
112
526
B90.1
ICD-10 Finland
Sequelae of genitourinary tuberculosis
+∞
13.6
13
*
J01FA06
ATC
roxithromycin; oral
1.8
13.5
319
2172
R03BB02
ATC
oxitropium bromide; inhalant
4.7
13.4
31
68
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
40.8
13.2
16
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.1
13.0
56
190
R03AC03
ATC
terbutaline; inhalant
2.2
12.5
115
567
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
132.0
12.5
13
*
J01MA14
ATC
moxifloxacin; systemic
2.4
12.5
94
426
R06.0
ICD-10 Finland
Dyspnoea
1.8
12.3
256
1671
49300
ICD-8 Finland
Asthma, bronchiale
3.7
12.1
39
110
01901
ICD-8 Finland
Late effects of tuberculosis, Emphysema
+∞
11.5
11
*
01930
ICD-8 Finland
Late effects of tuberculosis, Columnae vertebralis
+∞
11.5
11
*
R95
ICPC
Chron obstructive pulmonary disease
3.3
11.4
44
140
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
11.3
45
146
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
25.4
11.2
15
6
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.6
11.1
37
107
R05CB01
ATC
acetylcysteine; inhalant, oral
3.4
10.5
37
111
1370D
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,PLEURAFIBROOSI]
+∞
10.4
10
*
A15.3
ICD-10 Finland
Tuberculosis of lung, confirmed by unspecified means
+∞
10.4
10
*
1373X
ICD-9 Finland
Late effects of tuberculosis of bones and joints
+∞
10.4
10
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
12.2
10.4
18
15
7863A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Haemoptysis
9.3
10.1
20
22
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
40.6
10.0
12
*
H02AB07
ATC
prednisone; oral
1.9
9.7
141
817
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
4.9
9.6
21
44
78310
ICD-8 Finland
Symptoms referable to respiratory system, Haemoptysis
10.2
9.6
18
18
J01MA12
ATC
levofloxacin; systemic
1.8
9.4
180
1134
01106
ICD-8 Finland
Pulmonary tuberculosis, Pulmonum alia sive NUD
+∞
9.4
9
*
01903
ICD-8 Finland
Late effects of tuberculosis, Fibrosis pulmonum
+∞
9.4
9
*
R03AK08
ATC
formoterol and beclometasone; inhalant
3.2
9.0
35
112
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.5
9.0
30
87
1240
FHL
Bronchoscopy
3.5
9.0
31
92
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
50.6
8.7
10
*
01510
ICD-8 Finland
Tuberculosis of bones and joints, Of hip
+∞
8.3
8
*
01931
ICD-8 Finland
Late effects of tuberculosis, Coxae
+∞
8.3
8
*
01900
ICD-8 Finland
Late effects of tuberculosis, Bronchiectasia
+∞
8.3
8
*
J46
ICD-10 Finland
Status asthmaticus
3.3
8.2
31
98
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
10.2
7.6
14
14
R05
ICD-10 Finland
Cough
1.8
7.5
130
791
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.4
146
922
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
13.5
7.4
12
9
1370C
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,BRONKIEKTASIAT]
+∞
7.3
7
*
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
10.1
7.0
13
13
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.8
6.9
33
120
J96.0
ICD-10 Finland
Acute respiratory failure
3.4
6.9
24
72
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.8
295
2240
M16.7
ICD-10 Finland
Other secondary coxarthrosis
9.4
6.8
13
14
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
6.8
51
231
0110K, ,
ICD-8 Finland
40.4
6.8
8
*
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
40.4
6.8
8
*
Y3429
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Other inactive tuberculosis cases
40.4
6.8
8
*
J01FA10
ATC
azithromycin; systemic
1.5
6.5
283
2147
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.6
6.4
36
142
R96
ICPC
Asthma
2.0
6.4
71
374
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
70.4
6.4
7
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
6.0
6.3
16
27
51899
ICD-8 Finland
Bronchiectasis
11.1
6.3
11
10
R02
ICPC
Shortness of breath/dyspnoea
1.7
6.3
110
671
J42
ICD-10 Finland
Unspecified chronic bronchitis
3.9
6.3
18
47
1374X
ICD-9 Finland
Late effects of tuberculosis of other specified organs
+∞
6.3
6
*
A70
ICPC
Tuberculosis
26.9
6.2
8
*
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.0
6.2
17
43
J01CA04
ATC
amoxicillin; systemic
1.5
6.2
509
4359
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.2
6.2
48
221
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
12.6
6.1
10
8
XG466
NOMESCO Finland
Sleep oxymetry
2.8
6.1
30
111
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
8.7
6.1
12
14
R03BA08
ATC
ciclesonide; inhalant
2.2
6.1
50
236
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
6.0
101
1586

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
81
5.42
21.00
3.7
2.8
—
—
—
0
0
40
99
4.20
14.87
4.5
3.3
—
—
—
0
0
91
455
2.13
9.48
3.7
3.7
—
—
—
0
0
79
458
1.81
5.37
6.0
3.7
0.92
0.89
%
0.05
36
160
21
69
3.10
5.25
1.2
1.4
—
—
—
0
0
21
69
3.10
5.25
1.2
1.4
—
—
—
0
0
21
69
3.10
5.25
1.2
1.4
—
—
—
0
0
21
69
3.10
5.25
1.2
1.4
—
—
—
0
0
14
29
4.90
4.82
1.2
1.3
8.65
0.10
u/ml
—
9
19
137
953
1.53
4.60
7.2
4.6
—
—
—
0
0
121
821
1.56
4.55
7.0
6.1
2.85
1.14
mmol/l
3.78
108
653
71
431
1.71
4.16
6.5
3.8
0.07
0.12
%
0.36
28
133
83
526
1.65
4.14
1.3
1.3
346.67
460.48
titre
0.59
21
125
71
434
1.70
4.06
1.5
1.5
—
—
—
0
0
119
825
1.52
4.05
7.1
6.2
7.41
7.42
ph
0.52
81
490
69
420
1.70
4.01
6.1
3.7
0.98
0.58
%
0.60
28
140
9
14
6.49
3.99
1.2
1.4
—
—
—
0
0
310
2560
1.35
3.94
8.7
5.2
0.64
0.63
e9/l
0.34
281
2131
311
2575
1.34
3.87
8.8
5.2
0.04
0.04
e9/l
0.01
283
2151
319
2653
1.34
3.85
9.0
5.3
0.19
0.20
e9/l
0.46
290
2251
70
434
1.67
3.81
6.7
4.0
0.04
0.17
%
0.85
24
129
367
4231
0.75
3.81
4.9
5.0
1.45
1.44
mmol/l
0.29
330
3704
373
4284
0.75
3.73
4.9
5.1
4.25
4.29
mmol/l
0.29
337
3795
290
2388
1.34
3.71
9.4
5.4
61.26
59.81
%
1.16
277
2250
55
325
1.74
3.57
1.8
1.8
2.51
2.58
ug/l
0.01
48
266
44
243
1.86
3.56
1.3
1.3
—
—
—
0
0
31
152
2.08
3.50
4.8
4.1
—
—
—
0
0
312
2613
1.32
3.50
9.1
5.3
1.63
1.81
e9/l
1.84
286
2258
286
2380
1.32
3.32
4.1
3.6
1994.97
2312.45
ng/l
0.59
261
2081
14
48
2.95
3.31
1.9
3.1
16.01
15.28
%
0.43
14
48
287
2402
1.31
3.17
9.8
5.3
0.64
0.60
%
0.66
273
2216
356
4061
0.77
3.12
4.2
4.3
1.19
1.23
mmol/l
0.62
318
3501
389
4388
0.78
3.11
7.7
7.3
40.96
41.16
mmol/mol
0.16
354
3944
287
2411
1.30
3.06
9.8
5.4
9.21
9.16
%
0.08
272
2228
7
12
5.87
3.02
1.1
1.1
—
—
—
0
0
285
2407
1.29
2.88
9.8
5.3
2.73
2.78
%
0.17
270
2222
287
2434
1.28
2.79
9.9
5.5
23.27
24.55
%
1.17
275
2279
26
131
2.02
2.78
1.2
1.2
—
—
—
0
0
396
4421
0.79
2.73
5.5
6.0
2.36
2.41
mmol/l
0.59
358
3892
65
432
1.55
2.72
4.7
3.8
7.41
7.41
ph
0.47
57
359
216
1777
1.30
2.64
8.1
5.1
—
—
—
0
0
335
2913
1.26
2.61
12.3
8.2
4.57
4.48
e9/l
0.26
306
2490
24
121
2.01
2.58
2.1
1.6
—
—
—
0
0
458
5007
0.80
2.52
44.2
31.8
7.36
7.18
e9/l
0.91
448
4834
458
5005
0.80
2.50
44.5
32.1
126.59
128.26
g/l
1.63
450
4893
458
5004
0.80
2.49
44.2
31.8
4.21
4.26
e12/l
1.11
446
4834
458
5004
0.80
2.49
44.1
31.7
30.36
30.41
pg
0.20
451
4892
458
5004
0.80
2.49
45.0
32.3
38.34
38.36
%
0.03
449
4887
458
5004
0.80
2.49
44.6
31.8
242.95
234.90
e9/l
1.76
450
4852
458
5003
0.80
2.48
44.1
31.8
92.31
92.10
fl
0.42
451
4892
457
4986
0.80
2.41
38.5
29.0
88.36
89.03
umol/l
0.10
450
4867
7
17
4.14
2.36
1.1
1.1
—
—
—
0
0
126
1599
0.75
2.34
2.0
1.9
1.23
1.23
mmol/l
0.01
109
1282
454
4949
0.81
2.33
36.5
27.0
4.04
4.03
mmol/l
0.25
447
4803
82
592
1.43
2.32
8.5
5.6
12.22
12.57
mmol/l
0.14
71
555
454
4947
0.81
2.31
36.0
26.8
139.00
139.43
mmol/l
2.27
448
4808
9
28
3.24
2.31
1.3
1.3
—
—
—
0
0
76
1042
0.70
2.29
4.5
3.6
3.05
2.50
e6/l
0.17
41
564
27
150
1.83
2.22
3.7
2.5
86.95
88.16
%
0.39
27
145
37
226
1.67
2.21
1.1
1.1
—
—
—
0
0
31
181
1.74
2.18
1.1
1.2
—
—
—
0
0
130
1026
1.32
2.14
3.3
2.6
20.36
20.76
%
0.12
125
943
311
3506
0.81
2.12
5.5
4.8
—
0.40
—
0
10
137
1094
1.31
2.07
3.3
2.5
2.27
2.20
g/l
0.75
130
996
241
2064
1.24
2.05
5.6
4.4
—
—
—
0
0
439
4762
0.82
1.96
27.4
19.5
—
—
—
0
0
445
4819
0.82
1.94
16.1
12.4
21.50
22.71
u/l
1.23
431
4603
24
135
1.80
1.93
4.9
5.0
101.79
104.93
mmol/l
1.97
24
122
24
135
1.80
1.93
4.9
5.0
9.79
11.31
mmol/l
1.58
24
122
398
4354
0.83
1.92
5.6
5.3
2.02
2.08
mu/l
0.44
367
3837
23
128
1.82
1.91
1.3
1.3
1.15
1.15
g/l
0.01
23
123
144
1173
1.28
1.87
3.3
2.5
11.16
11.29
umol/l
0.09
135
1074
87
662
1.35
1.84
8.4
6.8
120.77
118.25
g/l
0.55
87
647
25
145
1.75
1.83
6.4
4.8
3.14
3.00
mmol/l
0.11
20
93
25
145
1.75
1.83
6.4
4.8
5.20
5.09
kpa
0.26
25
140
25
145
1.75
1.83
6.4
4.8
8.26
7.91
kpa
0.31
25
140
13
60
2.19
1.78
1.2
1.2
302.00
328.15
nmol/l
—
6
53
6
18
3.35
1.75
2.0
2.4
—
—
—
0
0
413
4480
0.84
1.74
5.4
5.6
6.10
6.18
mmol/l
0.56
365
3898
5
14
3.59
1.61
1.2
1.1
—
—
—
0
0
122
995
1.27
1.58
4.5
2.7
0.81
0.82
mmol/l
0.36
113
919
108
870
1.28
1.55
6.8
4.6
1.08
1.04
mmol/l
0.64
97
781
87
681
1.31
1.55
1.9
1.8
—
—
—
0
0
52
375
1.41
1.54
1.5
1.5
—
—
—
0
0
35
233
1.53
1.54
3.1
3.4
4.33
2.68
ratio
0.46
27
142
179
1534
1.22
1.49
3.1
2.9
29.46
34.85
u/l
1.34
173
1438
117
1415
0.80
1.48
3.1
3.2
2.46
2.47
mmol/l
0.35
101
1245
328
3596
0.85
1.47
4.5
4.1
15.66
15.25
pmol/l
1.94
302
3136
202
1754
1.20
1.46
2.8
2.5
63.67
62.22
u/l
0.07
189
1616
48
346
1.41
1.44
1.6
1.5
—
—
—
0
0
43
304
1.44
1.43
4.8
3.9
—
—
—
0
0
26
165
1.60
1.42
1.7
1.5
—
—
—
0
0
449
4789
0.85
1.38
32.1
21.6
29.60
29.68
mg/l
0.02
417
4198
46
332
1.41
1.38
1.4
1.4
—
—
—
0
0
90
1112
0.78
1.37
3.8
3.5
0.75
0.88
ug/l
1.02
66
795
9
43
2.11
1.30
1.2
1.4
—
—
—
0
0
73
573
1.30
1.30
2.3
1.4
—
—
—
0
0
79
627
1.29
1.30
3.3
2.6
65.68
65.52
g/l
0.06
70
555
8
34
2.37
1.29
1.1
1.2
—
—
—
0
0
33
227
1.47
1.28
1.2
1.3
—
—
—
0
0
11
55
2.01
1.27
1.8
1.5
65.83
72.42
%
—
6
38
9
44
2.06
1.27
1.2
1.4
—
—
—
0
0
36
254
1.44
1.24
3.0
3.6
60.18
76.94
mg/l
0.29
30
218
32
221
1.47
1.23
6.4
4.1
7.41
7.41
ph
0.27
32
216
36
255
1.43
1.22
3.0
3.6
34.58
49.64
mg/l
0.72
30
220
5
19
2.64
1.21
1.2
1.6
0.96
0.89
nmol/l
—
5
14
80
643
1.27
1.20
5.0
3.4
281.33
313.46
ng/l
0.34
73
592
175
1992
0.84
1.20
5.3
6.1
3.25
6.34
ug/l
0.71
156
1719
6
26
2.32
1.19
1.0
3.5
77.67
171.35
nmol/l
—
6
26
22
141
1.58
1.18
1.2
1.6
9505.86
16347.69
e6/l
0.58
14
94
48
361
1.35
1.16
11.2
7.8
15.31
15.40
%
0.09
48
346
5
20
2.51
1.15
1.6
1.4
0.32
0.15
nmol/l
—
5
12
11
58
1.91
1.12
3.9
3.8
—
—
—
0
0
43
320
1.36
1.12
5.2
4.0
1.74
1.54
%
0.72
43
300
5
21
2.39
1.09
2.4
1.0
6.54
6.87
u/l
—
5
21
80
654
1.25
1.06
1.4
1.3
17.25
8.58
u/ml
0.46
35
216
9
47
1.93
1.02
1.2
1.4
—
—
nmol/l
—
0
0
109
926
1.21
1.01
3.4
2.3
1.78
1.78
%
0.02
99
817
96
807
1.22
1.00
1.6
1.4
2.72
2.79
g/l
0.12
62
424
55
690
0.78
0.99
1.5
1.4
—
—
—
0
0
101
1186
0.83
0.99
1.4
1.3
—
—
—
0
0
17
108
1.59
0.97
1.8
1.4
—
—
—
0
0
14
85
1.66
0.94
2.9
3.0
4.99
4.71
e9/l
0.12
14
85
170
1904
0.86
0.94
2.8
2.4
—
—
—
0
0
7
37
1.90
0.94
1.4
1.3
20.96
30.02
ng/l
—
7
37
205
2262
0.87
0.92
5.0
4.5
122.15
136.76
e6/l
0.10
167
1702
160
1796
0.86
0.91
4.5
3.8
0.80
0.47
e6/l
0.50
138
1399
26
185
1.42
0.90
1.1
1.1
—
—
—
0
0
5
102
0.49
0.90
1.2
1.4
—
—
—
0
0
33
246
1.36
0.88
2.2
2.1
0.00
0.00
estimate
—
7
67
39
299
1.32
0.87
5.3
4.1
0.84
0.88
%
0.29
39
280
11
64
1.73
0.86
1.2
1.0
—
—
u/ml
—
0
0
189
2087
0.88
0.86
4.5
3.8
18.91
129.44
e6/l
2.77
165
1662
169
1880
0.87
0.85
2.7
2.1
210.34
275.88
u/l
0.48
161
1754
20
137
1.47
0.84
2.7
2.5
54.00
89.55
ug/min
0.58
14
83
79
668
1.20
0.80
1.3
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
11
66
1.68
0.79
1.1
1.2
—
—
—
0
0
84
718
1.19
0.76
1.4
1.3
31.73
35.42
iu/ml
0.16
31
234
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
6
34
1.77
0.76
1.3
1.3
106.00
91.21
pmol/l
—
6
34
180
1979
0.88
0.76
2.0
1.9
20.59
19.83
nmol/l
0.22
157
1648
15
99
1.53
0.76
1.7
1.6
3.46
68.87
iu/l
—
5
36
5
25
2.01
0.72
3.4
1.7
38.94
40.50
%
—
5
25
9
56
1.61
0.72
1.1
1.1
—
—
—
0
0
10
60
1.68
0.72
1.8
1.3
—
—
—
0
0
46
374
1.24
0.69
1.9
1.7
1.45
1.53
g/l
0.22
39
339
336
3172
1.10
0.68
9.6
6.7
1.21
1.21
mmol/l
0.05
295
2680
32
407
0.78
0.68
4.5
3.3
25.44
24.04
mmol/l
1.54
32
401
11
69
1.60
0.68
1.5
1.3
—
—
—
0
0
36
450
0.79
0.67
3.8
3.7
6.23
6.12
ph
0.37
30
343
17
119
1.44
0.67
1.8
1.9
1.07
0.85
%
—
10
85
5
28
1.79
0.66
2.4
2.1
—
—
—
0
0
318
3000
1.10
0.65
7.5
5.9
10.77
12.82
umol/l
3.28
307
2827
66
562
1.19
0.65
2.9
3.3
4.68
5.11
e9/l
0.33
56
460
152
1380
1.13
0.64
3.9
3.3
523.44
532.96
mosm/kgh2o
0.23
140
1210
81
704
1.17
0.63
2.9
2.4
67.06
66.62
e9/l
0.04
68
544
27
346
0.77
0.62
1.4
1.5
—
—
—
0
0
11
163
0.67
0.60
2.5
2.1
2.17
1.93
mg/l
0.34
11
134
15
105
1.44
0.60
3.3
3.1
61.47
61.95
%
0.05
15
105
169
1838
0.90
0.60
3.6
2.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
9.89
—
0
9
197
2123
0.90
0.59
3.3
3.3
2.32
2.35
mmol/l
3.33
176
1876
6
35
1.72
0.57
1.5
1.1
—
—
—
0
0
53
449
1.19
0.57
4.7
2.9
120.02
124.06
g/l
0.77
53
435
38
311
1.23
0.56
1.2
1.2
—
—
—
0
0
265
2810
0.91
0.56
2.5
2.4
89.58
92.34
pmol/l
0.40
142
1486
32
258
1.25
0.54
1.3
1.2
—
—
—
0
0
6
38
1.58
0.54
3.0
1.1
—
—
—
0
0
62
536
1.17
0.53
3.0
3.6
89.58
96.39
ng/l
0.28
46
452
167
1805
0.91
0.53
3.4
3.3
49.68
56.53
mg/l
0.16
120
1198
20
260
0.76
0.53
1.4
3.2
297.64
12061.87
u/ml
0.61
14
218
101
906
1.13
0.53
1.3
1.2
1.04
1.07
u/ml
0.03
29
207
124
1359
0.90
0.51
3.4
2.5
—
—
—
0
0
188
2016
0.91
0.51
5.4
4.4
—
0.75
—
0
8
11
75
1.47
0.51
2.5
2.0
89.39
88.52
%
0.24
11
75
107
1181
0.89
0.50
3.8
3.8
—
—
—
0
0
41
344
1.20
0.50
2.9
2.6
—
—
—
0
0
14
101
1.39
0.49
1.4
1.4
—
—
—
0
0
24
300
0.79
0.48
1.3
2.2
9.50
11.09
nmol/l
0.39
19
257
174
1866
0.91
0.48
4.3
4.0
10.45
9.57
mg/mmol
0.08
124
1197
98
885
1.12
0.47
2.4
1.9
—
—
—
0
0
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
366
3803
0.93
0.46
6.6
5.9
29.22
3216.79
e6/l
—
9
78
208
1956
1.09
0.45
5.5
4.0
7.40
7.40
ph
1.06
178
1421
5
32
1.57
0.42
12.0
3.8
1.20
0.84
index
—
5
32
6
95
0.63
0.42
1.0
1.1
—
—
—
0
0
222
2101
1.08
0.42
5.7
5.0
0.03
0.07
estimate
0.38
58
529
13
96
1.36
0.41
2.0
1.3
—
—
—
0
0
53
464
1.15
0.41
2.1
1.8
378.91
399.22
nmol/l
0.27
47
414
8
58
1.38
0.41
1.1
1.0
—
—
—
0
0
5
33
1.52
0.41
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.4
—
368.10
—
0
10
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
170
1810
0.92
0.40
3.5
3.3
6.49
6.75
mmol/l
0.40
143
1474
272
2598
1.07
0.40
5.7
4.7
71.69
85.00
ng/l
0.16
238
2099
174
1634
1.08
0.40
5.1
4.8
0.00
0.00
estimate
0.50
66
555
56
496
1.14
0.38
1.3
1.3
—
—
—
0
0
233
2218
1.07
0.37
4.8
4.2
6.35
6.34
ph
0.08
133
1204
20
161
1.25
0.37
1.6
1.4
5.42
10.32
iu/ml
—
5
41
24
198
1.22
0.36
1.1
1.1
214.46
125.60
u/ml
—
7
63
58
517
1.13
0.36
3.1
2.4
—
—
—
0
0
134
1250
1.09
0.36
5.3
5.2
1.02
1.02
kg/l
0.70
97
861
70
632
1.12
0.36
3.1
2.6
10.92
6.20
ug/l
0.35
56
526
5
79
0.63
0.35
1.0
1.1
—
—
—
0
0
21
172
1.23
0.34
6.7
4.1
1.08
1.51
index
0.31
12
91
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
39
445
0.87
0.33
1.5
2.0
134.31
162.79
ug/g
0.39
32
347
156
1473
1.07
0.32
5.3
4.4
0.00
0.10
estimate
1.19
57
488
26
220
1.19
0.32
6.2
5.3
—
—
—
0
0
11
83
1.33
0.32
6.2
5.5
12.99
13.43
mg/l
0.12
11
75
29
248
1.18
0.32
4.4
3.4
1.63
1.45
mmol/l
0.32
29
243
251
2410
1.06
0.31
3.0
2.4
83.48
79.94
nmol/l
0.96
220
2074
120
1123
1.08
0.31
2.4
1.7
1.68
1.60
mg/l
0.09
104
908
45
401
1.13
0.30
9.4
7.2
25.97
24.87
mmol/l
1.12
45
396
77
710
1.09
0.28
3.8
3.9
72.29
29.72
ug/l
0.40
71
608
195
1865
1.06
0.28
2.5
2.4
3.25
3.12
mg/l
0.30
173
1570
235
2436
0.95
0.26
3.6
2.9
—
—
estimate
—
0
0
56
512
1.10
0.25
2.4
2.2
0.00
0.00
estimate
—
10
89
14
170
0.82
0.25
2.9
2.2
52.05
58.33
%
0.51
14
165
241
2330
1.05
0.24
3.9
3.1
165.71
147.86
ug/l
0.44
226
2089
5
38
1.32
0.23
2.4
2.6
—
—
—
0
0
22
253
0.87
0.23
1.2
1.3
—
—
—
0
0
68
633
1.08
0.22
4.4
2.9
4.16
4.27
kpa
0.25
63
611
229
2217
1.05
0.21
18.7
12.6
0.00
0.00
e9/l
0.11
188
1789
10
124
0.80
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
132.57
—
0
11
5
43
1.16
0.21
5.6
3.7
85.40
108.40
u/ml
—
5
43
159
1528
1.05
0.20
9.4
6.2
—
—
—
0
0
326
3185
1.04
0.20
21.4
21.9
1.38
1.44
inr
0.88
285
2710
0
14
0.00
0.20
0.0
1.1
—
102.96
—
0
14
233
2261
1.04
0.20
4.4
3.9
—
—
—
0
0
6
50
1.20
0.19
1.5
1.2
—
—
—
0
0
6
53
1.13
0.18
2.7
2.8
8.07
8.12
mmol/l
—
6
53
7
62
1.13
0.17
1.1
1.1
—
—
—
0
0
5
70
0.71
0.16
1.8
2.1
—
—
—
0
0
284
2778
1.03
0.16
5.5
4.8
0.00
0.00
estimate
-0.00
75
634
157
1518
1.04
0.16
3.2
2.9
6.72
5.22
e6/l
0.52
149
1385
16
182
0.88
0.15
5.3
3.5
8.84
7.95
mmol/l
0.70
16
177
31
285
1.09
0.14
2.8
3.2
—
—
—
0
0
8
98
0.81
0.13
2.1
1.2
348.25
524.08
mg/l
—
8
93
24
218
1.10
0.13
5.0
2.7
333.75
289.62
mg/l
0.12
12
85
288
2828
1.03
0.13
5.5
4.8
0.00
0.49
estimate
0.51
76
626
49
518
0.94
0.12
2.3
2.4
28.93
33.05
u/l
0.72
43
429
147
1432
1.03
0.11
1.9
1.8
471.55
5040236.58
pmol/l
0.50
122
1131
15
167
0.90
0.10
4.3
1.8
20.20
20.84
s
0.41
15
157
12
106
1.13
0.10
6.4
2.6
16.26
12.50
pmol/l
0.40
12
106
13
116
1.12
0.09
1.9
1.6
—
—
—
0
0
288
2841
1.02
0.09
9.4
6.1
1.21
1.21
mmol/l
0.36
270
2567
11
124
0.89
0.09
1.2
1.3
—
—
—
0
0
6
55
1.09
0.09
1.8
1.8
—
—
—
0
0
12
134
0.89
0.08
1.9
1.4
—
—
—
0
0
285
2813
1.02
0.08
5.5
4.8
0.00
5.28
estimate
0.80
80
664
7
65
1.08
0.08
2.7
2.2
—
—
—
0
0
75
727
1.03
0.08
4.9
3.4
3.16
1.98
mmol/l
1.88
70
597
134
1312
1.03
0.08
6.4
4.5
122.77
253.52
ng/l
0.79
120
1184
8
75
1.07
0.07
2.9
1.2
—
—
—
0
0
60
580
1.04
0.07
10.7
7.3
—
—
—
0
0
10
89
1.13
0.07
1.3
1.1
—
—
—
0
0
28
295
0.95
0.06
2.5
2.1
—
—
—
0
0
10
110
0.91
0.05
2.4
1.4
—
—
—
0
0
136
1380
0.98
0.05
4.9
3.8
0.00
0.09
—
5
69
144
1421
1.02
0.04
4.2
2.9
356.72
368.49
umol/l
0.58
127
1183
146
1479
0.98
0.04
2.0
1.8
1178.31
1159.24
nmol/l
0.09
113
1092
12
111
1.08
0.04
1.3
1.2
27.74
42.26
u/l
0.52
12
97
15
159
0.94
0.03
1.1
1.2
—
—
—
0
0
404
4023
1.01
0.03
10.8
7.8
79.90
84.19
u/l
1.29
388
3747
16
168
0.95
0.02
11.8
14.2
—
—
—
0
0
26
252
1.03
0.02
2.8
2.0
279.40
417.02
ug/l
0.46
26
238
11
103
1.07
0.02
1.2
1.1
—
—
—
0
0
59
582
1.01
0.01
6.3
4.3
7.39
7.35
ph
3.43
40
401
280
2791
1.01
0.01
5.5
4.7
33.05
34.02
g/l
2.14
259
2559
273
2722
1.00
0.01
3.7
3.1
43.62
58.23
u/l
2.22
256
2463
15
156
0.96
0.00
2.2
1.4
253.22
273.09
ug/g
—
9
91
43
436
0.99
0.00
1.4
1.4
—
—
—
0
0
74
743
1.00
0.00
4.9
3.4
7.35
7.38
ph
1.32
43
468
45
448
1.00
0.00
6.2
4.5
—
—
—
0
0
340
3398
1.00
0.00
7.4
5.0
6.93
6.93
mmol/l
0.00
330
3253
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
43.00
—
0
5
0
5
0.00
0.00
0.0
5.2
—
0.78
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
90.67
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
54.00
—
0
9
5
49
1.02
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
0.02
—
0
9
5
52
0.96
-0.00
1.2
1.1
39.60
33.51
mmol/l
—
5
46
0
9
0.00
-0.00
0.0
1.1
—
7.22
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
70.57
—
0
7
5
57
0.88
-0.00
1.2
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_SEQULAE_TUBERCU_WIDE – Sequelae of tuberculosis, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).