No definition available.
Carcinoma in situ of middle ear and respiratory system
CD2_INSITU_EAR_RESP
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
95 |
4. Check minimum number of eventsNone |
95 |
5. Include endpoints |
182 |
6. Filter based on genotype QC (FinnGen only) |
161 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D00-D09
- Name in latin
- Carcinoma in situ auris mediae sive systematis respiratorii
Carcinoma in situ of middle ear and respiratory system
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 161 | 44 | 117 |
| Unadjusted period prevalence (%) | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | 68.80 | 67.26 | 69.39 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 165
- Matched controls
- 1650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D02.0
ICD-10 Finland
Carcinoma in situ: Larynx
+∞
58.9
53
*
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
118.3
48.0
50
6
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
130.1
45.6
47
5
UDQ12
NOMESCO Finland
Flexible laryngoscopy
9.7
31.8
43
58
DQA10
NOMESCO Finland
Biopsy of larynx
78.7
29.1
32
5
ZXC10
NOMESCO Finland
Use of laser
33.9
25.7
33
12
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
51.9
25.6
30
7
C32.9
ICD-10 Finland
Malignant neoplasm: Larynx, unspecified
+∞
22.4
21
*
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
252.0
22.2
22
*
UDQ22
NOMESCO Finland
Microlaryngoscopy
51.0
22.1
26
6
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
9.0
21.5
29
38
J38.3
ICD-10 Finland
Other diseases of vocal cords
31.9
20.8
27
10
8140/2-C34.1
ICD-O-3
Adenocarcinoma in situ, NOS, of upper lobe, lung
+∞
20.2
19
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.0
19.1
53
143
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
50.4
18.8
22
5
C320, 8077, 2
ICD-O-3
+∞
18.0
17
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.4
17.4
41
96
WF002
NOMESCO Finland
Radical radiotherapy
6.1
17.3
34
67
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
45.1
16.8
20
5
J37.0
ICD-10 Finland
Chronic laryngitis
13.8
16.3
28
24
EP1AE
NOMESCO Finland
Neck ultrasound examination
7.0
15.7
26
43
8070/2-C32.0
ICD-O-3
Squamous cell carcinoma in situ, NOS, of glottis
+∞
13.7
13
*
D02.2
ICD-10 Finland
Carcinoma in situ: Bronchus and lung
+∞
13.7
13
*
D02.3
ICD-10 Finland
Carcinoma in situ: Other parts of respiratory system
+∞
12.7
12
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.5
11.9
25
52
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
15.2
11.8
19
14
DQB30
NOMESCO Finland
Laryngectomy
70.1
11.8
13
*
WX734
NOMESCO Finland
JET-ventilation
+∞
11.6
11
*
UJC01
NOMESCO Finland
Scopy of lower throat
17.1
11.1
17
11
DQE00
NOMESCO Finland
Implantation of prosthetic replacement for larynx
64.3
10.8
12
*
DQB70
NOMESCO Finland
Total excision of vocal cord
117.2
10.5
11
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.9
10.4
78
387
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
+∞
9.5
9
*
130
Kela drug reimbursment
Malignant tumour
3.5
9.0
36
122
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.4
9.0
24
61
XX3DW
NOMESCO Finland
Time consuming IT work
3.4
9.0
38
134
8070/3-C32.0
ICD-O-3
Squamous cell carcinoma, NOS, of glottis
94.7
8.5
9
*
C32.1
ICD-10 Finland
Malignant neoplasm: Supraglottis
94.7
8.5
9
*
2310A
ICD-9 Finland
Carcinoma in situ of respiratory system, Larynx
+∞
8.4
8
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
14.0
8.0
13
10
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
11.6
7.4
13
12
8070/2-C32.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of larynx, NOS
+∞
7.3
7
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
31.5
7.2
9
*
A07AA02
ATC
nystatin; oral
4.3
6.9
19
49
R49.0
ICD-10 Finland
Dysphonia
13.0
6.7
11
9
WX402
NOMESCO Finland
General anaesthesia
2.7
6.7
42
184
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.9
6.5
20
56
C32.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of larynx
72.5
6.5
7
*
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
6.4
21
62
8140/2-C34.3
ICD-O-3
Adenocarcinoma in situ, NOS, of lower lobe, lung
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
13
23
6.04
5.18
1.4
1.3
—
—
—
0
0
11
20
5.81
4.37
1.2
1.1
—
—
—
0
0
14
43
3.46
4.01
1.4
1.3
—
—
—
0
0
69
478
1.76
3.08
4.0
3.3
2.35
2.35
mmol/l
0.11
64
422
12
40
3.15
2.76
1.5
1.5
—
—
—
0
0
7
15
4.82
2.62
1.9
1.5
—
—
—
0
0
82
624
1.62
2.43
3.2
3.1
—
—
estimate
—
0
0
9
28
3.34
2.34
1.8
2.1
—
—
—
0
0
8
23
3.60
2.30
1.8
1.3
—
—
—
0
0
92
734
1.57
2.15
7.0
7.6
1.20
1.20
mmol/l
0.03
82
631
5
11
4.65
1.95
2.4
1.3
—
—
—
0
0
91
737
1.52
1.90
11.9
10.7
4.42
4.34
e9/l
0.14
81
638
7
22
3.28
1.90
2.0
1.5
—
—
—
0
0
5
12
4.26
1.83
2.4
1.3
—
—
—
0
0
14
67
2.19
1.82
1.6
3.2
—
—
—
0
0
5
14
3.65
1.62
2.2
1.4
—
—
—
0
0
12
58
2.15
1.53
5.7
3.0
4.28
4.22
pmol/l
0.09
12
47
18
103
1.84
1.48
2.6
3.2
56.00
55.70
ml/min/173m2
—
7
44
19
112
1.79
1.43
1.5
1.3
—
—
—
0
0
46
345
1.46
1.32
3.0
3.0
—
—
—
0
0
8
35
2.35
1.29
1.8
1.1
—
—
—
0
0
6
121
0.48
1.10
1.3
1.5
—
—
—
0
0
9
48
1.92
1.02
1.7
1.8
—
—
—
0
0
9
50
1.85
0.98
1.8
1.7
—
—
—
0
0
28
204
1.45
0.93
4.8
5.2
33.18
32.40
%
0.13
17
131
63
528
1.31
0.90
3.1
3.4
—
—
—
0
0
24
173
1.45
0.85
6.3
3.7
—
—
—
0
0
34
278
1.28
0.57
2.1
2.1
—
—
—
0
0
26
206
1.31
0.55
1.6
1.9
—
—
—
0
0
35
291
1.26
0.52
1.9
1.7
1197.68
1130.57
nmol/l
0.22
30
216
64
569
1.20
0.51
2.2
2.4
79.42
77.06
nmol/l
0.31
59
489
104
1108
0.83
0.49
4.7
4.7
1.19
1.25
mmol/l
0.55
91
995
55
486
1.20
0.47
4.6
4.1
4.09
8.56
mg/mmol
1.61
30
317
82
751
1.18
0.46
4.8
3.4
58.91
58.63
u/l
0.01
74
696
19
148
1.32
0.46
4.2
6.5
9.63
10.93
mmol/l
0.32
19
143
25
304
0.79
0.46
4.4
4.6
1.02
1.02
kg/l
0.27
19
214
25
303
0.79
0.44
2.1
1.8
446.68
442.09
pmol/l
0.02
19
254
5
31
1.63
0.43
1.0
1.2
13.98
58.40
u/l
—
5
26
5
33
1.53
0.41
2.4
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
22
267
0.80
0.40
1.3
1.2
0.71
1.78
u/ml
—
7
64
95
890
1.16
0.38
5.8
4.1
15.32
15.06
pmol/l
0.44
86
772
42
474
0.85
0.37
1.8
2.1
1.32
1.26
mmol/l
0.22
33
379
23
190
1.24
0.37
1.7
2.0
—
—
—
0
0
15
188
0.78
0.35
1.8
1.3
43.16
37.85
iu/ml
—
7
68
12
91
1.34
0.35
2.3
4.0
24.35
23.95
mmol/l
0.24
12
91
46
411
1.17
0.34
3.2
3.4
0.59
0.53
e6/l
0.09
35
304
100
945
1.15
0.34
5.0
4.5
15.41
14.05
mm/h
0.30
91
864
88
935
0.87
0.34
34.8
25.6
14.20
13.98
%
0.78
88
925
20
165
1.24
0.33
2.4
4.0
6.07
5.76
kpa
0.72
20
156
73
678
1.14
0.32
3.5
4.2
0.00
0.00
estimate
-0.00
21
148
33
293
1.16
0.27
1.7
1.7
1.02
1.71
mg/l
1.32
24
234
8
67
1.20
0.26
1.3
2.2
—
—
—
0
0
5
74
0.67
0.26
2.8
2.0
3.36
3.58
g/l
—
5
68
5
74
0.67
0.26
2.8
2.0
6.10
7.31
g/l
—
5
68
5
74
0.67
0.26
2.8
2.0
4.08
4.07
g/l
—
5
68
14
170
0.81
0.26
1.4
1.3
45.38
8.06
u/ml
—
6
58
114
1182
0.89
0.26
5.9
6.5
2.31
2.51
mmol/l
1.59
102
1074
73
688
1.11
0.23
3.5
4.2
0.00
10.61
estimate
0.50
20
153
119
1151
1.12
0.23
25.9
20.2
74.07
73.50
ml/min/173m2
0.11
113
1066
5
39
1.29
0.23
2.2
1.5
—
—
—
0
0
11
135
0.80
0.23
2.5
2.9
0.58
0.25
e6/l
0.32
11
129
68
640
1.11
0.22
2.3
2.3
94.96
93.47
pmol/l
0.10
50
334
5
41
1.23
0.22
2.2
1.5
—
—
—
0
0
44
405
1.12
0.21
4.3
4.2
0.00
0.02
estimate
0.50
15
131
0
11
0.00
0.21
0.0
1.0
—
48.02
—
0
6
0
11
0.00
0.21
0.0
1.0
—
473.67
—
0
6
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
45
415
1.12
0.21
2.8
2.1
3.15
3.05
mg/l
0.08
39
354
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
11
133
0.81
0.20
1.1
1.3
—
—
—
0
0
16
137
1.19
0.19
2.3
3.2
4.80
4.31
kpa
0.59
16
129
49
459
1.10
0.17
1.7
1.9
26.54
20.87
nmol/l
0.28
42
373
5
67
0.74
0.17
2.8
2.0
9.28
10.93
g/l
—
5
60
5
69
0.72
0.17
2.8
2.0
2.76
3.03
g/l
—
5
63
112
1151
0.92
0.17
5.2
5.5
1.42
1.42
mmol/l
0.06
99
1040
123
1200
1.10
0.17
26.3
20.6
30.51
28.18
mg/l
0.32
111
1027
38
352
1.10
0.16
2.5
3.2
383.44
351.58
umol/l
0.74
27
303
73
698
1.08
0.16
3.5
4.3
0.00
0.00
estimate
-0.00
19
136
14
121
1.17
0.15
2.1
2.2
8.15
12.98
nmol/l
1.84
14
104
40
375
1.09
0.14
3.5
3.7
0.00
0.00
estimate
-0.00
15
116
10
117
0.85
0.13
6.7
10.9
94.97
93.94
%
—
10
117
65
626
1.06
0.11
6.8
4.8
37.11
48.19
ng/l
0.43
58
495
115
1172
0.94
0.10
6.2
5.7
6.21
6.16
mmol/l
0.16
102
1055
22
238
0.91
0.10
2.5
3.4
1.79
2.07
e6/l
—
10
124
15
135
1.12
0.10
1.7
3.0
67.13
66.31
g/l
0.16
15
126
28
262
1.08
0.10
2.4
1.9
28.89
29.50
s
0.23
28
250
5
46
1.09
0.09
2.2
1.5
—
—
—
0
0
23
247
0.92
0.09
2.7
3.2
0.69
0.95
e6/l
0.38
11
129
5
62
0.80
0.08
1.0
1.0
—
—
—
0
0
39
408
0.94
0.08
3.8
3.4
0.92
0.82
ug/l
0.48
32
292
10
88
1.15
0.08
1.1
1.5
—
—
—
0
0
114
1158
0.95
0.08
5.1
5.6
4.26
4.36
mmol/l
0.44
103
1054
9
84
1.08
0.07
2.3
1.3
—
—
—
0
0
8
90
0.88
0.07
2.9
4.5
53.50
46.19
%
—
8
85
53
516
1.04
0.05
4.0
4.4
0.00
0.03
estimate
0.50
17
120
18
169
1.07
0.05
4.6
9.5
—
—
—
0
0
112
1107
1.04
0.04
7.1
5.1
1.98
2.01
mu/l
0.10
101
972
54
551
0.97
0.03
3.9
3.6
783.94
1548.03
ng/l
2.18
48
464
54
549
0.98
0.02
6.0
5.1
21.96
22.18
%
0.04
37
296
26
254
1.03
0.00
2.5
2.5
2.26
2.22
g/l
0.17
26
236
114
1144
0.99
0.00
8.7
7.4
40.38
40.87
mmol/mol
0.28
104
1055
59
594
0.99
0.00
2.2
2.5
—
—
—
0
0
29
285
1.02
0.00
5.5
3.9
156.03
303.96
ng/l
0.46
23
241
70
703
0.99
0.00
6.7
6.1
3.26
2.75
ug/l
0.23
62
611
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.31
—
0
5
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
9.44
—
0
5
6
64
0.94
-0.00
1.3
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
97
0.92
-0.00
1.3
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
17.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
4.65
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_EAR_RESP – Carcinoma in situ of middle ear and respiratory system
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).