No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1443 |
4. Check minimum number of eventsNone |
1443 |
5. Include endpointsNone |
1443 |
6. Filter based on genotype QC (FinnGen only) |
1279 |
Control definitions (FinnGen only)
- Control exclude
- I9_CEREBVASC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I60-I69
- Name in latin
- Alia haemorrhagia intracranialis non traumatica
Similar endpoints
↥List of similar endpoints to
Other intracranial haemorrhages
based on the number of shared cases.
Similar with more cases:
- Cerebrovascular diseases
- Bleeding
- STROKE
- Neurological diseases, wide definition
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10757 | 4015 | 6617 |
| Only index persons | 8357 | 3132 | 5225 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.12 | 0.18 |
| Only index persons | 0.17 | 0.12 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 74.17 | 76.06 | 73.01 |
| Only index persons | 73.90 | 75.44 | 72.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1279 | 404 | 875 |
| Unadjusted period prevalence (%) | 0.32 | 0.14 | 0.40 |
| Median age at first event (years) | 73.07 | 70.10 | 74.44 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1311
- Matched controls
- 13110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
56.6
317.6
181
37
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
59.8
307.7
659
218
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
136.6
307.7
550
69
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
16343.6
307.7
1007
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
129.9
307.7
269
26
AA1AD
NOMESCO Finland
CT of head and brain
7.6
293.4
859
2626
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
+∞
293.0
270
*
K90
ICPC
Stroke/cerebrovascular accident
27.1
151.5
105
42
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
20.1
147.9
116
63
I62.1
ICD-10 Finland
Nontraumatic extradural haemorrhage
+∞
145.6
137
*
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
53.9
141.6
81
16
N03AX14
ATC
levetiracetam; systemic
12.3
121.7
125
111
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
538.2
102.0
100
*
W19
ICD-10 Finland
Unspecified fall
4.5
101.7
292
777
X59
ICD-10 Finland
Exposure to unspecified factor
3.7
96.3
403
1399
ZXD05
NOMESCO Finland
Urgent procedure
3.2
93.1
591
2648
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
37.5
86.7
54
15
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.0
83.4
650
3223
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
9.9
80.1
95
103
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
79.0
75
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
280.4
78.4
79
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
793.2
77.1
75
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.2
73.9
135
240
K91
ICPC
Cerebrovascular disease
29.9
73.6
49
17
G91.0
ICD-10 Finland
Communicating hydrocephalus
30.4
71.0
47
16
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
67.3
64
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
62.9
445
2033
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
+∞
57.7
55
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
52.4
50
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
6.2
51.9
92
158
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
12.3
51.7
52
44
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
271.0
51.5
52
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
180.3
50.3
52
*
R51.80
ICD-10 Finland
Headache
3.2
48.0
219
774
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
+∞
46.1
44
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
11.9
45.8
47
41
XA800
NOMESCO Finland
Neuropsychological investigation
7.2
45.7
69
100
ZXD35
NOMESCO Finland
Usual procedure
5.5
45.5
91
175
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.6
43.0
153
461
PA6AD
NOMESCO Finland
CT of neck arteries
5.9
42.9
80
144
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
7.6
40.9
59
81
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
14.1
40.0
37
27
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.3
39.9
162
531
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
108.4
38.9
42
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
38.8
292
1334
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.3
38.4
105
262
AAD12
NOMESCO Finland
Drainage of subdural fluid
72.1
37.1
42
6
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.5
37.1
54
75
B01AA03
ATC
warfarin; systemic
2.2
37.0
439
2436
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.1
36.0
77
157
N18
ICPC
Paralysis/weakness
8.2
35.1
47
59
AA1AA
NOMESCO Finland
Head X-ray examination
9.6
34.6
41
44
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
34.5
146
489
R41.0
ICD-10 Finland
Disorientation, unspecified
4.1
33.4
95
244
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.6
33.1
54
85
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
32.4
31
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
32.2
127
407
N03AF02
ATC
oxcarbazepine; oral
5.3
31.6
65
128
AAF00
NOMESCO Finland
Ventriculostomy
32.5
31.4
41
13
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
31.4
30
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
31.2
318
1644
N03AB02
ATC
phenytoin; systemic
8.6
31.0
40
48
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
5.1
29.6
63
128
R42
ICD-10 Finland
Dizziness and giddiness
2.1
29.5
375
2106
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
+∞
29.3
28
*
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
58.1
29.2
34
6
R4120
NOMESCO Finland
Occupational therapy
3.7
28.6
94
267
PA2AD
NOMESCO Finland
CT angiography of brain
27.1
27.2
37
14
Y96.9
ICD-10 Finland
Unspecified type of accident
5.7
26.0
49
89
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.5
25.5
90
268
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
71.3
24.9
28
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.9
24.6
461
2929
S06.3
ICD-10 Finland
Focal brain injury
6.7
24.4
39
60
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.2
24.3
100
328
WX002
NOMESCO Finland
Sedation and analgesia
2.0
23.6
299
1661
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
+∞
23.0
22
*
N19
ICPC
Speech disorder
7.3
22.5
33
46
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
35.7
22.1
28
8
N80
ICPC
Head injury other
4.7
22.1
51
111
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
21.9
21
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
21.1
1139
9827
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
213.2
20.6
21
*
R53
ICD-10 Finland
Malaise and fatigue
1.9
20.5
350
2139
Z2445
NOMESCO Finland
Psychologist
5.3
19.7
40
78
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
7.6
19.1
27
36
H53.4
ICD-10 Finland
Visual field defects
5.1
19.1
40
80
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
18.7
903
7328
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
18.6
814
6430
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.2
18.1
49
121
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
15.6
18.0
29
19
S06.0
ICD-10 Finland
Concussion
2.2
17.7
153
728
N05AH04
ATC
quetiapine; oral
2.0
17.7
205
1093
C07AB07
ATC
bisoprolol; oral
1.7
17.5
757
5914
N03AG01
ATC
valproic acid; systemic, rectal
3.0
17.3
80
281
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
172.1
16.5
17
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
23.4
16.5
23
10
F05.9
ICD-10 Finland
Delirium, unspecified
3.7
16.4
52
144
N29
ICPC
Neurological sympt/complt other
4.5
16.4
40
91
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
16.3
685
5275
Z3231
NOMESCO Finland
Registered nurse
1.7
15.9
366
2415
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
60.8
15.8
18
*
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
+∞
15.7
15
*
I63.8
ICD-10 Finland
Other cerebral infarction
+∞
15.7
15
*
N28
ICPC
Limited function/disability (N)
4.2
15.6
41
99
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
15.4
253
1512
SPAT1216
SPAT
Assessment of functional ability
1.8
15.4
263
1591
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
15.2
245
1455
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.3
15.2
58
182
L28
ICPC
Limited function/disability (L)
1.7
14.8
314
2020
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
14.4
14.6
24
17
R47.0
ICD-10 Finland
Dysphasia and aphasia
11.0
14.5
27
25
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
151.6
14.5
15
*
SPAT1229
SPAT
Assessment of need for aid
2.2
14.4
135
662
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
14.4
201
1138
PA7BD
NOMESCO Finland
CT angiography of neck and brain
5.3
14.4
29
56
SPAT1234
SPAT
Support of social functional capacity
2.4
14.2
104
460
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
14.2
172
929
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
30.4
13.9
18
6
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
30.4
13.9
18
6
SPAT1053
SPAT
Memory test
1.7
13.6
282
1797
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
13.5
88
369
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.8
13.3
65
236
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
15.2
13.1
21
14
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.9
13.0
61
216
A28
ICPC
Limited function/disability NOS
1.7
12.8
321
2147
N06AX11
ATC
mirtazapine; oral
1.6
12.6
398
2817
FFW96
NOMESCO Finland
Other operation on atria
70.6
12.6
14
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
32.4
12.6
16
5
X58
ICD-10 Finland
Exposure to other specified factors
1.9
12.6
164
907
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
+∞
12.5
12
*
P20
ICPC
Memory disturbance
1.7
12.5
273
1762
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
12.2
369
2581
R55
ICD-10 Finland
Syncope and collapse
1.8
12.2
182
1051
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.5
12.1
41
119
N05CF01
ATC
zopiclone; oral
1.6
12.1
435
3168
N05AX08
ATC
risperidone; systemic
2.0
12.1
140
743
WX882
NOMESCO Finland
High dependency care
3.1
11.9
49
161
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
5.1
11.5
24
48
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
+∞
11.5
11
*
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
+∞
11.5
11
*
AA5PD
NOMESCO Finland
CT examination of brain pefusion
13.8
11.5
19
14
B01AC04
ATC
clopidogrel; oral
1.7
11.4
249
1602
ZXA05
NOMESCO Finland
Left side
1.6
11.4
340
2367
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
8.4
11.3
24
29
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
14.0
11.0
18
13
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.9
533
4120
WX892
NOMESCO Finland
Monitored bed care
2.1
10.9
110
555
J01DB01
ATC
cefalexin; oral
1.6
10.9
967
8442
B01AB05
ATC
enoxaparin; parenteral
1.5
10.8
409
2996
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
10.8
442
3292
SPAT1254
SPAT
Administration of medicine
1.7
10.8
218
1372
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.2
10.8
94
448
G41.9
ICD-10 Finland
Status epilepticus, unspecified
9.7
10.8
21
22
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.9
10.7
31
81
R50.9
ICD-10 Finland
Fever, unspecified
1.7
10.7
207
1289
C03CA01
ATC
furosemide; systemic
1.5
10.6
557
4361
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
10.5
209
1309
ABB40
NOMESCO Finland
Evacuation of spontaneous haematoma of spinal canal
110.9
10.4
11
*
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
+∞
10.4
10
*
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
+∞
10.4
10
*
I62
ICD-10 Finland
Other nontraumatic intracranial haemorrhage
+∞
10.4
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
10.4
440
3297
B01AC07
ATC
dipyridamole; systemic
2.3
10.3
82
377
C10AA01
ATC
simvastatin; oral
1.5
10.2
632
5102
K78
ICPC
Atrial fibrillation/flutter
1.8
10.2
148
847
ZXE00
NOMESCO Finland
One hour or less
1.5
10.1
455
3449
N03AX18
ATC
lacosamide; systemic
10.1
10.0
19
19
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.0
10.0
112
588
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
9.9
213
1362
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
9.9
98
491
SPAT1153
SPAT
Removal of sutures
1.5
9.9
423
3169
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
9.8
90
438
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
9.6
182
1126
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
9.5
227
1491
WX872
NOMESCO Finland
Intensive care
2.2
9.4
79
371
I61.6
ICD-10 Finland
Intracerebral haemorrhage, multiple localized
+∞
9.4
9
*
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
9.4
9
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
9.4
9
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
21.9
9.4
13
6
S06.9
ICD-10 Finland
Intracranial injury, unspecified
7.0
9.3
22
32
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
10.7
9.3
17
16
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.7
9.1
167
1021
C09AA02
ATC
enalapril; systemic
1.5
9.1
303
2148
S18
ICPC
Laceration/cut
1.4
9.1
597
4835
G40.10
ICD-10 Finland
Simple partial seizures
8.4
9.1
19
23
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
15.7
9.0
14
9
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
18.7
8.9
13
7
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.2
8.9
23
55
Y94.0
ICD-10 Finland
Accident at home
3.4
8.9
32
97
TKC20
NOMESCO Finland
Catheterisation of bladder
1.9
8.9
116
640
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
8.9
101
532
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
8.9
86
428
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
8.8
368
2734
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
8.8
76
362
X57
ICD-10 Finland
Unspecified privation
3.2
8.7
34
109
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
50.3
8.7
10
*
N03AF01
ATC
carbamazepine; oral, rectal
2.2
8.6
70
325
F80.1
ICD-10 Finland
Expressive language disorder
9.0
8.5
17
19
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
27.7
8.5
11
*
R1250
NOMESCO Finland
Evaluation of functional capability
2.9
8.5
38
132
N99
ICPC
Neurological disease other
3.9
8.4
24
62
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
90.6
8.4
9
*
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
+∞
8.3
8
*
A02BC02
ATC
pantoprazole; systemic
1.4
8.3
825
7139
R4110
NOMESCO Finland
Physiotherapy
1.5
8.3
317
2307
SPAT1252
SPAT
Overall medication plan or its review
1.9
8.3
109
603
WYA20
NOMESCO Finland
Home visit
2.7
8.3
42
156
S01.0
ICD-10 Finland
Open wound of scalp
1.8
8.3
119
678
F03
ICD-10 Finland
Unspecified dementia
2.0
8.2
91
475
R51
ICD-10 Finland
Headache
2.5
8.2
50
204
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
14.6
8.2
13
9
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.8
8.1
24
64
C08CA01
ATC
amlodipine; oral
1.4
8.1
533
4292
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
8.0
169
1073
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
8.0
170
1082
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.0
8.0
83
424
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.1
8.0
71
342
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.3
8.0
18
25
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
4.5
7.9
19
43
SPAT1360
SPAT
Extensive global examination
1.9
7.9
95
511
E86
ICD-10 Finland
Volume depletion
2.5
7.9
49
202
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.5
7.8
15
16
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.8
279
2003
SPAT1301
SPAT
No procedures
1.4
7.7
400
3080
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.0
7.7
33
112
XX2BT
NOMESCO Finland
Other injection with X-ray guidance
18.5
7.6
11
6
R11
ICD-10 Finland
Nausea and vomiting
1.8
7.6
107
606
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
25.2
7.6
10
*
S06.4
ICD-10 Finland
Epidural haemorrhage
25.2
7.6
10
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.5
209
1419
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
7.5
101
564
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.5
356
2698
N05BA04
ATC
oxazepam; oral
1.5
7.5
299
2193
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.4
7.4
49
208
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.4
294
2152
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
7.7
7.4
16
21
N01
ICPC
Headache
1.9
7.4
86
458
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
7.4
63
299
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
7.4
111
642
N88
ICPC
Epilepsy
8.4
7.3
15
18
SPAT1263
SPAT
Sampling
1.4
7.3
480
3846
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
7.3
80
417
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
+∞
7.3
7
*
PA5HT
NOMESCO Finland
Embolisation of extensive arterio-venous malformation of carotis externa area
+∞
7.3
7
*
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
+∞
7.3
7
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.7
7.2
139
862
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.1
7.2
66
322
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
3.7
7.2
22
60
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
7.1
366
2808
C09AA05
ATC
ramipril; oral
1.4
7.1
365
2801
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
7.0
108
628
R06AE07
ATC
cetirizine; oral
1.4
6.9
404
3165
N30.0
ICD-10 Finland
Acute cystitis
1.6
6.9
172
1137
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
6.9
80
425
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.9
259
1872
G44.2
ICD-10 Finland
Tension-type headache
1.7
6.9
115
685
WX704
NOMESCO Finland
Intubation
1.9
6.8
90
500
205
Kela drug reimbursment
Chronic hypertension
1.4
6.8
419
3313
S06.8
ICD-10 Finland
Other intracranial injuries
40.3
6.8
8
*
R4130
NOMESCO Finland
Speech therapy
3.0
6.7
29
99
XF404
NOMESCO Finland
Ambulatory ECG
1.7
6.7
117
707
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
22.6
6.7
9
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.6
6.7
36
139
A10AB05
ATC
insulin aspart; parenteral
1.8
6.7
98
563
C10AA05
ATC
atorvastatin; oral
1.4
6.6
533
4393
WX730
NOMESCO Finland
Conventional respirator
3.2
6.6
25
79
K99
ICPC
Cardiovascular disease other
2.3
6.6
49
220
XA400
NOMESCO Finland
EEG
8.7
6.6
13
15
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.5
92
522
Z43.0
ICD-10 Finland
Attention to tracheostomy
14.4
6.4
10
7
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
14.4
6.4
10
7
H3603, E103,
ICD-10 Finland
14.4
6.4
10
7
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
6.4
53
249
NFQ20
NOMESCO Finland
Amputation of femur
4.1
6.4
17
42
K27
ICPC
Fear cardiovascular disease other
3.6
6.3
20
56
NF3AA
NOMESCO Finland
Femur X-ray examination
2.6
6.3
36
143
G41.0
ICD-10 Finland
Grand mal status epilepticus
18.1
6.3
9
5
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
+∞
6.3
6
*
PA2PT
NOMESCO Finland
Permanent closure of brain artery
+∞
6.3
6
*
C08CA06
ATC
nimodipine; systemic
+∞
6.3
6
*
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
6.3
6
*
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
6.3
6
*
G04CA02
ATC
tamsulosin; oral
1.4
6.2
459
3723
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
6.2
37
150
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.0
6.2
61
306
S06.2
ICD-10 Finland
Diffuse brain injury
5.1
6.2
18
36
G72.8
ICD-10 Finland
Other specified myopathies
2.7
6.1
31
116
TFP20
NOMESCO Finland
Cardiodefibrillation
1.7
6.1
112
686
AAF15
NOMESCO Finland
Ventriculoatrial shunt
8.6
6.1
12
14
F05.1
ICD-10 Finland
Delirium superimposed on dementia
3.6
6.0
19
53
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.0
190
1323
XCK00
NOMESCO Finland
Perimetry
1.8
6.0
80
446
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
423
1638
3.34
83.63
2.5
2.0
30.31
29.96
s
0.42
414
1584
637
3298
2.81
72.72
3.0
2.1
244.53
275.88
u/l
0.24
621
3081
854
5845
2.32
45.04
26.7
19.9
1.41
1.37
inr
1.00
766
4949
64
90
7.42
43.50
2.2
1.3
—
—
—
0
0
930
6713
2.33
41.52
8.2
5.1
6.93
6.89
mmol/l
0.24
906
6413
87
181
5.08
39.79
2.4
1.3
44.72
62.08
e6/l
0.16
72
133
88
185
5.03
39.77
2.4
1.4
25510.34
308.08
e6/l
0.57
77
142
742
5035
2.09
36.71
3.7
2.9
—
—
estimate
—
0
0
469
2764
2.08
33.12
3.3
2.5
—
—
—
0
0
357
1950
2.14
30.37
3.3
3.0
0.82
0.82
mmol/l
0.16
341
1822
300
1559
2.20
28.79
8.9
6.8
0.72
1.04
mmol/l
0.65
246
1261
299
1561
2.19
28.31
9.1
6.8
4.93
5.09
kpa
2.19
289
1493
671
4665
1.90
28.02
5.5
4.4
67.26
90.80
ng/l
0.30
582
3725
297
1560
2.17
27.62
9.1
6.8
13.19
11.64
kpa
4.76
286
1494
38
50
7.80
27.29
1.9
2.3
—
—
—
0
0
807
6048
1.87
25.68
10.1
7.5
1.20
1.21
mmol/l
1.84
714
5144
237
1209
2.17
23.39
7.2
6.6
10.33
11.87
mmol/l
2.24
231
1156
244
1284
2.11
22.14
10.0
7.5
117.71
120.02
g/l
1.03
238
1247
257
1412
2.02
20.62
9.5
7.0
96.73
95.14
%
8.33
251
1361
717
5410
1.72
20.04
9.3
6.7
1.20
1.21
mmol/l
2.75
667
4946
30
43
7.12
19.98
2.2
1.2
—
—
—
0
0
286
1653
1.93
19.75
5.9
5.6
1.02
1.04
mmol/l
0.90
273
1532
174
857
2.19
18.52
10.6
8.5
1.30
1.31
%
0.08
174
851
82
283
3.02
18.30
3.0
2.3
3.79
3.64
g/l
0.37
77
267
885
7226
1.69
17.07
6.3
5.1
1594.90
2009.41
e6/l
0.16
21
128
71
241
3.06
16.31
2.5
2.5
28.30
34.91
umol/l
1.83
66
212
169
864
2.10
16.27
9.8
5.9
24.66
24.40
mmol/l
0.38
163
825
755
5979
1.62
15.85
8.6
6.7
12.58
12.95
umol/l
0.33
711
5712
209
1175
1.93
15.37
4.4
3.1
4.66
4.37
kpa
0.91
204
1138
237
1418
1.82
14.28
5.1
3.5
5.73
5.81
kpa
0.56
230
1371
351
2347
1.68
14.26
2.2
2.0
—
—
—
0
0
354
2439
1.62
12.54
2.0
1.8
1171.18
1184.51
nmol/l
0.10
278
1816
666
5293
1.52
12.48
6.0
5.1
34.05
34.56
g/l
1.50
630
4909
223
1381
1.74
11.79
5.2
3.5
1.35
1.86
mmol/l
1.06
189
1158
266
1740
1.66
11.46
2.0
1.9
—
—
—
0
0
475
3572
1.52
11.20
3.2
2.6
59.06
82.86
u/l
0.53
449
3299
156
883
1.87
11.10
4.6
3.2
126.69
127.54
g/l
0.17
150
860
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
95
451
2.19
11.01
3.4
2.4
0.36
0.32
iu/ml
0.48
50
229
161
926
1.84
10.88
4.2
4.3
5.12
5.16
kpa
0.25
153
885
194
1187
1.74
10.65
9.7
6.9
1.32
1.38
mmol/l
0.52
189
1165
28
68
4.19
10.64
1.8
1.4
1.13
0.95
promille
0.22
23
48
127
687
1.94
10.36
1.6
1.5
—
—
—
0
0
724
6016
1.45
9.90
11.8
9.3
4.40
4.37
e9/l
0.13
635
5152
20
23
8.81
9.79
1.1
1.3
92.14
82.81
%
—
7
16
449
3424
1.47
9.53
2.4
2.4
3.32
2.96
mg/l
1.71
384
2917
156
928
1.77
9.41
1.7
1.6
—
—
—
0
0
332
2388
1.52
9.35
4.9
4.3
142.63
408.40
ng/l
4.31
287
2094
506
3965
1.45
9.26
4.2
3.6
57.56
103.80
e6/l
1.02
421
3139
138
796
1.82
9.22
4.1
4.1
1.55
2.12
mmol/l
0.81
96
596
79
376
2.17
9.12
3.7
4.0
8.06
7.84
kpa
0.56
74
370
937
8241
1.48
9.11
11.1
8.4
84.33
82.51
u/l
0.47
885
7762
242
1633
1.59
9.03
2.0
1.9
—
—
—
0
0
19
24
8.02
8.86
1.1
2.2
104.67
78.76
%
—
6
17
128
738
1.81
8.56
11.5
9.0
15.66
15.77
%
0.16
123
705
1073
9760
1.55
8.37
30.0
19.4
26.92
29.11
mg/l
1.59
986
8314
112
624
1.87
8.36
6.5
4.3
1.53
1.57
%
0.31
106
585
359
2698
1.46
7.95
1.8
1.8
426.39
14833839.78
pmol/l
1.26
289
2191
112
639
1.82
7.76
2.0
1.8
2.67
2.72
ug/l
0.01
92
566
371
2819
1.44
7.71
3.3
2.8
3.55
4.17
e6/l
0.77
347
2577
204
1382
1.56
7.40
3.2
2.7
65.26
67.54
e9/l
0.49
160
1054
698
5945
1.37
7.27
4.2
3.3
68.43
58.29
u/l
0.94
644
5416
235
1654
1.51
7.15
6.0
4.1
243.76
248.30
u/l
0.24
222
1558
532
4347
1.38
7.14
4.2
3.4
1885.52
1886.42
ng/l
0.00
482
3829
27
85
3.22
7.14
1.6
1.2
3.10
1.61
u/ml
0.71
20
23
124
748
1.73
7.12
4.4
2.8
1.37
1.16
%
1.19
124
742
658
5577
1.36
6.94
5.1
4.1
0.00
0.00
estimate
0.50
141
1234
667
5676
1.36
6.80
5.2
4.2
9.65
5.38
estimate
0.17
141
1272
115
696
1.72
6.53
3.8
3.4
24.99
25.04
mmol/l
0.06
109
668
56
268
2.14
6.45
1.5
1.5
—
—
—
0
0
120
738
1.69
6.43
4.5
2.8
0.65
0.61
%
0.86
120
732
282
2099
1.44
6.41
2.9
2.7
2.20
2.22
g/l
0.28
257
1931
18
47
3.87
6.27
1.0
1.1
—
—
—
0
0
665
5700
1.34
6.26
5.2
4.2
0.02
0.26
estimate
0.45
131
1188
412
3286
1.37
6.23
3.7
3.1
33.24
36.49
u/l
0.69
394
3081
68
356
1.96
6.16
2.8
3.3
0.91
0.82
nmol/l
0.66
48
281
297
2246
1.42
6.16
3.0
2.7
11.89
11.91
umol/l
0.02
276
2074
562
4709
1.34
6.13
3.3
3.1
178.12
157.86
ug/l
0.89
516
4287
173
1179
1.54
6.08
2.9
2.6
4.03
6.33
ug/l
4.10
151
1030
26
89
2.96
6.02
1.7
1.1
9.11
2.61
u/ml
0.88
18
38
422
3401
1.36
5.92
4.0
3.5
0.51
0.45
e6/l
0.15
340
2594
294
2236
1.41
5.88
2.9
1.6
2.18
1.73
mg/l
0.77
240
1776
482
4004
1.32
5.40
3.9
3.5
2.35
2.35
mmol/l
0.02
444
3583
134
887
1.57
5.36
1.9
1.7
—
—
—
0
0
137
918
1.55
5.20
2.5
2.2
382.69
376.11
nmol/l
0.15
126
836
404
3291
1.33
5.14
5.1
4.2
0.00
0.00
estimate
0.78
122
1108
457
3790
1.32
5.12
2.0
1.8
19.31
19.65
nmol/l
0.15
395
3151
501
4209
1.31
5.10
5.4
4.3
0.02
0.05
estimate
0.39
121
1033
1091
10207
1.41
5.08
36.2
24.0
139.32
139.58
mmol/l
2.18
1076
9980
318
2505
1.36
5.05
5.8
4.4
1.02
1.02
kg/l
0.26
220
1707
257
1964
1.38
4.93
3.0
2.7
21.96
21.68
%
0.12
240
1818
1091
10221
1.40
4.92
36.0
24.2
4.02
4.02
mmol/l
0.20
1076
9974
84
508
1.70
4.83
2.1
1.8
—
—
—
0
0
109
709
1.59
4.72
1.8
1.8
1.45
1.54
g/l
0.43
93
623
88
550
1.64
4.49
2.2
1.9
—
—
—
0
0
253
1967
1.35
4.32
3.6
3.4
2.86
1.83
e6/l
0.87
140
1055
269
2113
1.34
4.30
3.5
3.3
1.47
1.05
e6/l
0.41
157
1204
35
165
2.15
4.28
8.5
6.9
6.70
7.36
mmol/l
0.83
28
139
834
7590
1.27
4.16
36.5
25.9
331.09
331.42
g/l
0.45
828
7532
540
4669
1.27
4.16
2.6
2.4
76.14
78.80
nmol/l
1.40
485
4062
62
364
1.74
4.01
1.5
1.6
—
—
—
0
0
186
1402
1.38
3.85
9.8
8.5
—
—
—
0
0
612
5412
1.25
3.75
2.5
2.3
87.60
93.06
pmol/l
2.48
381
2958
30
141
2.15
3.73
1.1
1.4
149.27
150.76
au/ml
0.02
11
32
1092
10342
1.33
3.70
38.0
26.4
90.21
87.22
umol/l
1.33
1077
10180
10
20
5.03
3.69
1.1
1.1
—
—
—
0
0
116
810
1.47
3.67
1.9
1.7
1.81
1.55
%
1.76
99
669
59
352
1.71
3.63
1.7
1.8
—
—
—
0
0
10
22
4.57
3.43
1.1
1.1
—
—
—
0
0
10
22
4.57
3.43
1.0
1.1
—
—
—
0
0
537
4722
1.23
3.36
2.7
2.5
—
—
—
0
0
10
23
4.37
3.31
1.0
1.1
—
—
—
0
0
30
149
2.04
3.27
1.0
1.2
238.74
306.14
u/ml
0.80
19
73
6
7
8.60
3.26
1.0
1.1
—
—
—
0
0
9
19
4.76
3.24
1.0
1.1
—
—
—
0
0
10
24
4.19
3.19
1.1
1.2
—
—
—
0
0
1070
10159
1.29
3.17
16.6
12.8
25.35
24.80
u/l
0.36
1035
9760
830
7660
1.23
3.16
5.2
4.4
15.84
14.51
mm/h
1.33
776
7018
1094
10419
1.30
3.14
43.3
29.5
7.19
7.00
e9/l
1.85
1072
10089
78
519
1.53
3.14
4.3
3.6
54.85
63.68
mg/l
0.30
66
440
1093
10417
1.30
3.06
43.2
29.4
92.04
91.93
fl
0.30
1078
10238
1093
10417
1.30
3.06
43.4
29.5
230.15
236.02
e9/l
1.73
1071
10131
6
8
7.53
3.05
1.0
1.3
—
—
—
0
0
1093
10418
1.30
3.05
43.3
29.5
4.28
4.38
e12/l
7.57
1071
10090
1093
10418
1.30
3.05
44.5
30.0
38.77
39.55
%
4.49
1078
10232
123
901
1.40
3.04
3.2
3.2
55.15
58.89
ml/min/173m2
0.48
52
414
1093
10420
1.29
3.03
43.7
29.7
129.02
132.43
g/l
9.64
1080
10242
77
518
1.52
2.96
4.3
3.6
39.30
92.17
mg/l
1.02
66
442
295
2461
1.26
2.92
3.2
3.1
2.47
2.46
mmol/l
0.43
271
2197
157
1205
1.34
2.92
3.3
2.8
65.12
66.01
g/l
0.68
143
1101
19
82
2.34
2.92
1.1
1.0
178.83
333.08
ng/l
—
6
51
19
82
2.34
2.92
1.1
1.0
25.17
44.22
ng/l
—
6
50
19
82
2.34
2.92
1.1
1.0
625.00
601.52
ng/l
—
6
50
128
952
1.38
2.90
3.7
3.8
107.79
101.06
ng/l
0.28
106
815
74
499
1.51
2.82
5.4
4.7
24.25
24.97
mmol/l
1.29
69
458
17
71
2.41
2.80
2.4
2.3
—
—
—
0
0
38
217
1.77
2.78
1.7
1.9
1.94
1.68
mmol/l
0.57
33
210
53
332
1.62
2.78
2.1
2.3
130.51
127.60
g/l
0.39
45
260
7
14
5.02
2.73
1.6
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
48
2.73
2.72
1.0
1.1
—
—
—
0
0
13
48
2.73
2.72
12.6
8.1
68.69
72.74
%
0.20
13
39
67
448
1.52
2.67
1.4
1.3
—
—
—
0
0
12
43
2.81
2.65
1.5
2.8
5.49
4.90
kpa
0.32
12
43
12
43
2.81
2.65
1.5
2.8
10.16
10.05
kpa
0.04
12
43
70
474
1.50
2.64
3.9
3.4
3.32
4.08
ratio
0.15
42
294
163
1278
1.31
2.63
3.8
3.9
—
—
—
0
0
7
15
4.69
2.60
1.6
1.1
—
—
—
0
0
12
44
2.74
2.55
1.7
1.3
11.36
20.99
umol/l
1.37
12
38
6
11
5.47
2.54
1.2
1.3
—
—
—
0
0
6
11
5.47
2.54
1.2
1.4
—
—
—
0
0
13
50
2.62
2.53
1.9
1.7
65.75
65.12
umol/l
—
8
33
50
318
1.60
2.49
2.1
1.6
0.43
0.32
mg/l
0.37
20
147
159
1253
1.31
2.48
3.8
2.7
8.63
10.16
umol/l
0.56
145
1125
19
89
2.15
2.45
1.6
1.3
—
—
—
0
0
19
89
2.15
2.45
2.1
2.6
8.87
7.51
mmol/l
0.63
19
89
18
84
2.16
2.35
1.2
1.1
108.39
110.31
%
0.08
18
71
44
276
1.61
2.34
10.0
5.7
11.38
11.39
mmol/l
0.00
39
242
44
276
1.61
2.34
10.0
5.7
105.72
105.10
mmol/l
0.30
39
242
19
91
2.10
2.33
1.6
1.3
—
—
—
0
0
15
65
2.32
2.32
1.1
1.1
97.33
98.47
%
0.05
15
59
42
261
1.63
2.32
4.7
4.3
1.12
1.66
%
0.67
33
230
6
13
4.63
2.27
1.0
1.1
—
—
—
0
0
7
18
3.90
2.25
2.6
2.3
—
—
—
0
0
9
29
3.12
2.22
1.2
1.1
1.08
1.11
ratio
—
9
22
124
961
1.32
2.20
4.3
4.0
1.21
1.22
mmol/l
0.50
113
822
105
795
1.35
2.18
3.4
3.0
11.05
11.00
g/l
0.03
97
722
55
371
1.50
2.16
1.6
1.7
9.62
7.27
iu/ml
0.25
13
83
976
9292
1.20
2.15
7.8
7.3
41.24
40.49
mmol/mol
1.62
897
8492
68
480
1.44
2.13
2.8
2.6
0.71
1.44
g/l
1.61
55
401
24
130
1.86
2.13
3.2
2.7
—
—
—
0
0
148
1182
1.28
2.11
2.6
2.2
0.20
0.20
g/l
0.08
141
1096
943
8957
1.19
2.10
5.5
5.0
2.10
2.08
mu/l
0.13
854
8024
8
25
3.21
2.09
11.0
16.2
644.38
793.96
nmol/l
—
8
25
348
3049
1.19
2.08
4.0
3.0
370.82
365.05
umol/l
0.39
299
2616
69
491
1.43
2.08
1.3
1.4
108.00
53.46
au/ml
—
5
45
57
391
1.48
2.07
2.1
2.4
0.00
0.04
g/l
1.75
48
348
9
31
2.92
2.07
1.3
1.1
—
—
—
0
0
5
10
5.01
2.07
1.2
1.3
—
—
—
0
0
15
69
2.19
2.05
2.0
2.2
—
—
—
0
0
977
9321
1.19
2.01
28.0
19.5
70.39
71.88
ml/min/173m2
1.42
932
8717
11
44
2.51
2.01
1.0
1.2
—
—
—
0
0
14
63
2.24
2.01
1.8
1.3
—
—
—
0
0
14
63
2.24
2.01
1.4
1.4
—
—
—
0
0
14
63
2.24
2.01
1.4
1.4
—
—
—
0
0
14
63
2.24
2.01
1.8
1.3
—
—
—
0
0
8
27
2.97
1.93
2.1
1.1
—
—
—
0
0
30
180
1.68
1.93
5.2
4.4
53.46
57.72
%
0.40
24
158
17
86
1.99
1.85
1.2
1.1
—
—
—
0
0
70
513
1.39
1.82
2.2
2.5
2.96
3.01
g/l
0.15
59
457
75
560
1.36
1.75
2.1
2.5
3.74
3.81
g/l
0.13
64
504
75
561
1.36
1.73
2.1
2.5
4.21
4.13
g/l
0.32
64
506
75
561
1.36
1.73
2.1
2.5
7.34
7.43
g/l
0.17
64
505
8
30
2.68
1.72
2.0
1.6
0.61
0.62
mmol/l
—
8
30
32
202
1.60
1.72
4.1
3.3
12.13
11.59
pmol/l
0.08
32
202
35
226
1.56
1.72
4.4
5.5
520.80
430.84
iu/ml
—
5
31
330
2927
1.17
1.69
4.7
3.8
0.03
0.05
estimate
0.12
115
954
22
126
1.76
1.68
1.9
1.6
—
—
—
0
0
6
19
3.17
1.66
1.0
1.2
—
—
—
0
0
46
319
1.46
1.64
1.3
1.3
—
—
—
0
0
348
3877
0.86
1.63
2.1
1.9
1.38
1.29
mmol/l
1.10
290
3143
777
7341
1.14
1.61
4.4
3.9
15.06
15.09
pmol/l
0.10
706
6534
22
128
1.73
1.61
1.5
1.2
283.06
275.58
mosm/kgh2o
0.61
17
91
926
8858
1.15
1.60
4.6
4.5
1.29
1.26
mmol/l
0.58
835
7865
48
338
1.44
1.59
1.7
1.5
253.24
271.79
ug/g
0.26
29
215
6
20
3.01
1.58
2.8
2.3
—
—
—
0
0
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
9
38
2.38
1.45
3.3
2.2
21.22
16.89
nmol/l
—
9
33
13
67
1.95
1.38
2.2
1.5
105.46
91.96
umol/l
0.26
13
67
6
23
2.62
1.37
1.2
1.3
—
—
—
0
0
18
105
1.72
1.33
1.3
1.4
—
—
—
0
0
12
61
1.98
1.33
1.7
1.4
1.14
2.86
u/field
—
7
42
64
490
1.32
1.32
2.0
2.6
10.37
10.75
g/l
0.25
51
432
444
4091
1.13
1.29
4.5
4.3
13.48
8.37
mg/mmol
1.29
311
2664
51
379
1.36
1.28
2.6
2.5
0.00
0.00
g/l
-0.00
41
329
5
18
2.78
1.28
1.2
2.1
42.00
38.33
u/l
—
5
18
5
18
2.78
1.28
1.0
1.2
1.21
1.17
mmol/l
—
5
18
63
490
1.30
1.19
3.4
3.2
4.28
4.39
pmol/l
0.36
56
422
6
26
2.31
1.18
1.3
1.2
—
—
—
0
0
42
308
1.38
1.17
2.4
2.4
121.71
123.58
ug/min
0.01
27
178
978
9469
1.13
1.14
5.9
5.7
6.19
6.12
mmol/l
0.97
877
8440
30
208
1.45
1.13
1.4
1.4
—
—
—
0
0
7
31
2.26
1.10
1.1
1.0
173.00
158.94
iu/ml
—
7
31
26
179
1.46
1.03
3.3
3.2
—
2483.28
—
0
18
80
655
1.24
1.02
3.8
3.8
1.02
1.02
ratio
0.61
72
605
45
342
1.33
1.02
1.6
1.6
—
—
—
0
0
71
872
0.80
1.02
1.3
1.5
—
—
—
0
0
10
53
1.89
1.01
1.6
1.2
73.30
88.63
u/l
—
10
46
29
206
1.42
0.99
1.5
1.2
—
—
—
0
0
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
8
142
0.56
0.93
1.1
1.2
1.43
1.51
g/l
—
8
142
128
1472
0.86
0.93
1.2
1.3
21.05
12.68
u/ml
0.46
45
498
19
126
1.52
0.91
1.3
1.8
—
—
—
0
0
18
118
1.53
0.91
1.3
1.8
—
—
—
0
0
803
7744
1.10
0.88
35.0
24.0
14.19
13.96
%
3.90
798
7631
12
193
0.62
0.88
1.0
1.1
—
—
—
0
0
11
64
1.72
0.86
1.1
1.1
—
—
—
0
0
8
44
1.82
0.86
3.4
2.1
788.50
1467.30
u/ml
—
8
44
17
112
1.52
0.85
1.2
1.3
—
—
—
0
0
8
45
1.78
0.84
1.3
5.5
—
38.71
—
0
7
17
113
1.51
0.82
2.4
2.0
2.14
1.59
u/field
—
7
59
39
302
1.30
0.82
4.0
3.6
2.08
1.75
index
0.12
25
153
8
47
1.71
0.80
1.3
1.3
165.34
173.87
pmol/l
—
8
47
6
33
1.82
0.79
1.3
1.0
1422.17
1285.58
miu/ml
—
6
33
45
358
1.27
0.78
1.0
1.0
—
—
—
0
0
31
235
1.33
0.76
1.8
1.7
—
—
—
0
0
9
53
1.70
0.75
1.1
1.0
—
—
—
0
0
63
524
1.21
0.74
3.1
2.7
—
—
—
0
0
141
1580
0.88
0.74
1.2
1.3
67.60
37.12
iu/ml
0.92
47
485
569
5436
1.08
0.73
6.5
6.4
7.39
4.32
ug/l
0.39
512
4825
428
4042
1.09
0.73
3.7
3.5
7.14
7.38
mmol/l
0.59
362
3356
7
39
1.80
0.72
1.3
1.5
—
—
—
0
0
7
39
1.80
0.72
1.1
1.0
—
—
—
0
0
132
1173
1.14
0.71
4.4
3.2
311.61
247.41
ng/l
0.50
124
1082
21
151
1.40
0.71
1.5
1.4
—
—
—
0
0
21
151
1.40
0.71
1.5
1.4
—
—
—
0
0
9
58
1.56
0.70
1.0
1.2
195.67
597.72
u/l
—
9
53
21
152
1.39
0.69
1.5
1.4
—
—
—
0
0
33
257
1.29
0.69
1.4
1.2
3.28
5.95
u/ml
—
5
33
11
69
1.60
0.68
1.6
1.6
2757.09
6571.29
u/l
—
5
17
955
9331
1.09
0.67
5.4
5.3
4.12
4.37
mmol/l
11.04
873
8439
21
153
1.38
0.67
1.5
1.4
—
—
—
0
0
36
285
1.27
0.67
1.6
1.4
—
—
—
0
0
976
9551
1.09
0.64
6.2
6.2
2.32
2.51
mmol/l
9.63
886
8609
10
154
0.65
0.64
1.1
1.2
0.86
0.89
g/l
—
10
154
21
155
1.36
0.63
1.5
1.4
—
—
—
0
0
12
79
1.52
0.62
1.0
1.0
—
—
—
0
0
22
164
1.35
0.62
1.7
1.4
9.79
8.76
u/l
0.18
16
131
17
121
1.41
0.62
1.6
1.3
0.74
15.43
nmol/l
0.49
17
115
460
4386
1.08
0.61
5.2
5.2
22.88
22.03
%
0.59
262
2426
16
113
1.42
0.61
1.4
1.6
21.72
37.99
ng/l
0.86
16
113
21
156
1.35
0.61
1.5
1.4
—
—
—
0
0
50
417
1.21
0.60
2.1
2.0
37.34
38.48
u/l
0.17
42
363
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
51.51
—
0
21
36
291
1.24
0.58
1.3
1.6
16466.29
17289.52
e6/l
0.05
24
202
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
30
238
1.27
0.57
1.5
1.7
8.23
4.35
mg/l
0.52
24
192
6
36
1.67
0.56
1.2
1.1
—
—
—
0
0
11
73
1.51
0.56
3.1
3.1
44.60
67.67
u/ml
0.28
11
73
11
73
1.51
0.56
4.0
3.5
1.64
0.99
%
0.41
11
73
5
90
0.55
0.55
2.8
2.8
31.60
32.29
mg/l
—
5
63
89
1004
0.88
0.55
1.3
1.4
—
—
—
0
0
14
99
1.42
0.54
1.7
1.6
—
—
—
0
0
6
39
1.54
0.53
1.2
1.2
—
—
—
0
0
31
250
1.25
0.52
1.4
1.4
—
—
—
0
0
29
232
1.26
0.52
1.6
1.4
1241.22
5620.96
e6/l
0.60
23
160
26
326
0.79
0.52
1.6
1.7
—
—
—
0
0
941
9231
1.07
0.50
5.4
5.2
1.33
1.42
mmol/l
8.32
851
8282
17
127
1.34
0.49
1.2
1.4
15.88
13.58
u/l
0.60
17
118
29
356
0.81
0.49
1.6
1.8
—
—
—
0
0
40
335
1.20
0.49
1.6
1.6
—
—
—
0
0
26
208
1.26
0.48
1.5
1.3
46901.44
101082.00
e6/l
0.55
18
118
34
282
1.21
0.46
1.5
1.5
0.15
21.99
iu/ml
—
10
55
10
142
0.70
0.46
3.3
3.3
—
—
—
0
0
22
175
1.26
0.43
1.6
1.3
—
—
—
0
0
6
95
0.63
0.42
1.0
1.0
—
1.44
—
0
31
8
60
1.34
0.40
1.3
1.4
0.15
0.25
nmol/l
—
8
40
25
205
1.22
0.39
1.6
1.7
3.55
5.36
iu/l
—
9
75
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
30
254
1.19
0.35
1.6
1.3
—
—
—
0
0
30
254
1.19
0.35
1.6
1.3
—
—
—
0
0
33
282
1.17
0.35
2.4
3.4
460.11
1262.84
u/ml
0.39
28
259
14
108
1.30
0.35
1.4
1.3
23181.11
54464.64
e6/l
—
9
74
25
209
1.20
0.34
1.0
1.1
—
6.93
—
0
14
15
118
1.27
0.33
1.3
1.6
—
—
—
0
0
15
118
1.27
0.33
1.3
1.6
—
—
—
0
0
15
118
1.27
0.33
1.3
1.6
—
—
—
0
0
10
76
1.32
0.28
1.3
1.2
—
—
—
0
0
17
203
0.84
0.26
1.4
1.3
—
—
—
0
0
35
311
1.13
0.25
1.3
1.3
—
—
—
0
0
53
484
1.10
0.24
4.4
3.3
568.52
3645.23
u/ml
0.82
46
410
6
82
0.73
0.24
1.0
1.1
—
—
—
0
0
323
3136
1.04
0.23
3.7
3.6
1.20
0.81
ug/l
1.30
230
2271
182
1747
1.05
0.22
1.8
1.5
2.91
2.81
g/l
0.24
111
1013
5
41
1.22
0.22
2.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
5.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
55.05
—
0
12
0
12
0.00
0.21
0.0
1.8
—
0.75
—
0
12
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.7
1.8
—
—
—
0
0
6
48
1.25
0.20
1.7
1.8
—
—
—
0
0
6
50
1.20
0.19
1.7
1.8
—
—
—
0
0
109
1037
1.06
0.19
2.3
2.2
142.91
144.59
ug/g
0.02
79
810
6
52
1.15
0.19
3.2
1.9
38.53
38.92
g/l
—
6
52
198
1916
1.04
0.18
1.2
1.2
0.82
1.22
u/ml
1.31
48
474
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
7
63
1.11
0.17
1.9
1.5
4.71
7.98
u/l
—
7
53
8
71
1.13
0.16
2.5
4.0
148.13
128.00
nmol/l
—
8
71
11
92
1.20
0.16
2.4
1.9
106.73
119.88
ng/l
0.28
11
92
47
438
1.08
0.16
1.1
1.2
89.52
144.72
u/ml
0.75
16
147
8
73
1.10
0.15
1.4
1.1
—
—
—
0
0
29
317
0.91
0.15
1.5
1.5
—
—
—
0
0
100
960
1.05
0.14
2.6
2.3
11.23
12.62
nmol/l
0.65
90
825
30
326
0.92
0.14
1.3
1.2
—
—
—
0
0
29
266
1.09
0.14
1.3
1.3
—
—
—
0
0
137
1414
0.97
0.13
4.0
4.2
43.89
27.66
ug/l
0.24
120
1188
11
94
1.17
0.13
1.7
1.4
—
—
—
0
0
96
996
0.96
0.12
3.7
2.6
29.58
40.83
u/l
1.52
83
814
27
249
1.09
0.12
1.7
1.4
—
—
—
0
0
27
251
1.08
0.10
1.2
1.1
—
—
—
0
0
27
252
1.07
0.09
1.2
1.1
—
—
—
0
0
6
55
1.09
0.09
3.0
3.6
0.83
0.91
index
—
6
55
19
175
1.09
0.08
2.1
1.6
—
—
—
0
0
8
77
1.04
0.07
2.0
1.5
—
—
—
0
0
13
118
1.10
0.07
1.8
1.6
—
—
—
0
0
20
214
0.93
0.07
1.1
1.4
1.31
0.82
nmol/l
0.92
14
176
9
103
0.87
0.06
1.3
2.1
—
—
—
0
0
67
688
0.97
0.05
1.4
1.4
—
—
—
0
0
17
182
0.93
0.05
1.4
1.4
7.27
6.14
mmol/l
0.95
17
171
18
169
1.07
0.05
2.1
1.6
—
—
—
0
0
10
108
0.93
0.03
1.4
1.4
—
—
—
0
0
14
132
1.06
0.02
1.1
1.0
—
—
—
0
0
13
126
1.03
0.00
1.5
2.0
—
—
—
0
0
27
266
1.02
0.00
1.4
1.6
—
—
—
0
0
14
139
1.01
0.00
1.3
1.4
—
—
—
0
0
137
1368
1.00
0.00
5.5
5.2
33.22
33.04
%
0.05
89
833
27
265
1.02
0.00
3.0
3.6
28.89
32.03
mg/l
0.15
19
185
10
95
1.05
0.00
1.1
1.2
—
—
—
0
0
7
70
1.00
-0.00
1.6
1.7
—
—
—
0
0
8
81
0.99
-0.00
2.0
1.5
—
—
—
0
0
7
70
1.00
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
7
70
1.00
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
70
1.00
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2.40
—
0
5
9
92
0.98
-0.00
1.2
1.2
102.89
97.57
pmol/l
—
9
92
8
81
0.99
-0.00
2.6
3.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
6.23
—
0
6
8
89
0.90
-0.00
1.1
1.4
—
60.00
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_OTHINTRACRA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_OTHINTRACRA | 2.148 [1.85, 2.49] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.346 |
During the follow-up period (1.1.1998 — 31.12.2019), 1445 out of 2816 females with I9_OTHINTRACRA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_OTHINTRACRA | 2.024 [1.74, 2.35] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 2569 out of 4843 males with I9_OTHINTRACRA died.
Mortality risk
Mortality risk for people of age
years, who have I9_OTHINTRACRA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.205% | 0.342% |
| 5 | 1.286% | 2.021% |
| 10 | 3.13% | 5.194% |
| 15 | 6.112% | 10.143% |
| 20 | 10.484% | 17.079% |
Relationships between endpoints
↥Index endpoint: I9_OTHINTRACRA – Other intracranial haemorrhages
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data