No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1141 |
4. Check minimum number of eventsNone |
1141 |
5. Include endpointsNone |
1141 |
6. Filter based on genotype QC (FinnGen only) |
1034 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF10
Major anomalies of jaw size
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13353 | 6803 | 6524 |
| Only index persons | 12168 | 6223 | 5945 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.19 | 0.18 |
| Only index persons | 0.23 | 0.23 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 16.68 | 17.52 | 15.76 |
| Only index persons | 17.56 | 18.45 | 16.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1034 | 612 | 422 |
| Unadjusted period prevalence (%) | 0.21 | 0.22 | 0.19 |
| Median age at first event (years) | 27.55 | 30.30 | 23.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1076
- Matched controls
- 10760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
83.6
307.7
187
27
K07.13
ICD-10 Finland
Retrognaty, mandibular
29.7
303.9
210
87
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
+∞
272.9
250
*
SBB10
NOMESCO Finland
Dental impressions
8.3
222.9
376
656
EEC05
NOMESCO Finland
Le Fort I osteotomy
95.1
212.4
111
13
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
14.6
207.2
201
167
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
12.1
204.3
227
233
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
11.9
204.1
230
241
K07.14
ICD-10 Finland
Retrognaty, maxillary
82.8
184.1
98
13
5240A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Major anomalies of jaw size
+∞
182.6
170
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
11.7
182.2
205
213
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
11.1
181.4
213
235
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
8.9
176.0
250
352
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
11.7
172.7
193
198
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
65.0
151.9
84
14
SJC10
NOMESCO Finland
Orthodontic band in one tooth
10.5
146.0
174
194
52430
ICD-8 Finland
Dento-facial anomalies including malocclusion, Anomalies of tooth position
+∞
145.2
136
*
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
15.4
143.9
131
96
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
+∞
139.7
131
*
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
9.0
133.8
181
237
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
+∞
132.1
124
*
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
35.9
131.2
83
25
SAA04
NOMESCO Finland
Special examination of mouth
6.9
129.6
229
404
K07.10
ICD-10 Finland
Asymmetry of jaw
55.0
126.3
72
14
K07.24
ICD-10 Finland
Open bite
17.1
125.6
107
69
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
8.4
120.6
172
239
4344
FHL
Osteotomy and shaping of the lower jaw (jaw deformities)
590.7
109.9
107
*
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
7.9
106.5
158
229
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
9.3
99.2
126
151
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
8.6
97.1
132
172
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
8.9
96.9
128
161
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
50.6
91.4
53
11
K07.23
ICD-10 Finland
Deep bite
7.1
88.4
144
230
K07.0
ICD-10 Finland
Major anomalies of jaw size
+∞
81.3
77
*
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
+∞
80.2
76
*
K07.60
ICD-10 Finland
Snapping jaw
5.6
78.8
167
344
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
36.6
78.1
49
14
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
7.1
77.7
124
193
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
101.2
77.2
84
9
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
+∞
74.9
71
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.0
73.5
119
188
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
7.1
73.3
117
182
EBB10
NOMESCO Finland
Insertion of dental implant
14.5
73.0
67
49
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.0
68.0
162
368
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
8.1
64.9
91
122
EBB15
NOMESCO Finland
Insertion of dental implant abutment
22.3
63.3
47
22
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
15.1
62.6
56
39
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
4.2
60.6
186
514
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
9.5
59.0
72
81
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.5
56.3
235
799
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
104.0
54.4
59
6
4347
FHL
Osteotomy of the upper jaw
189.3
52.4
54
*
4343
FHL
Lower jaw open osteotomy
181.9
50.3
52
*
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
5.3
49.5
105
214
SPC20
NOMESCO Finland
Implant borne crown
18.0
49.1
40
23
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.0
48.2
111
243
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
4.7
48.2
118
272
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
46.2
44
*
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
10.2
44.8
51
52
52400
ICD-8 Finland
Dento-facial anomalies including malocclusion, Major anomalies of jaw size
+∞
43.0
41
*
4305
FHL
Tooth extraction by cutting
14.4
42.7
39
28
K00.00
ICD-10 Finland
Hypodontia
8.1
40.3
55
71
K07.4
ICD-10 Finland
Malocclusion, unspecified
6.6
40.1
66
105
SXC05
NOMESCO Finland
Other oral or dental procedure
3.3
39.5
173
598
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
39.1
517
3075
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
10.4
38.2
43
43
SAA03
NOMESCO Finland
Extended examination of mouth
2.3
38.1
591
3743
SXC03
NOMESCO Finland
Other oral or dental procedure
11.5
37.3
39
35
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
9.9
34.3
40
42
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.8
33.2
106
297
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
46.0
33.0
40
9
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
6.9
33.0
52
79
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.9
31.5
97
265
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
45.1
28.8
35
8
EDC30
NOMESCO Finland
Genioplasty
106.3
28.8
31
*
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
5.9
28.4
52
92
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
8.0
27.8
38
49
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
8.5
26.2
34
41
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.7
26.0
154
623
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
5.8
25.9
48
86
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
10.2
24.8
28
28
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.8
24.8
57
124
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.0
23.6
110
390
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
23.5
529
3617
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
23.0
22
*
9165
FHL
Removal of osteosynthesis material
6.1
22.3
39
66
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
63.9
21.9
25
*
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
6.2
21.7
37
61
5241A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Anomalies of relationship of jaw to cranial base
44.3
21.5
26
6
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.8
20.9
33
50
ZXA10
NOMESCO Finland
Bilateral
2.2
20.5
201
1016
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
33.3
20.2
26
8
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
8.0
19.2
26
33
52410
ICD-8 Finland
Dento-facial anomalies including malocclusion, Anomalies of jaw-cranial base relationships
+∞
18.8
18
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
18.1
104
412
G50.1
ICD-10 Finland
Atypical facial pain
5.1
17.2
36
72
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
15.1
17.2
28
19
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
7.6
17.0
24
32
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
22.3
16.9
24
11
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
5.6
16.3
31
57
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.7
16.2
38
84
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.2
16.1
159
801
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.5
16.1
55
161
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
3.4
16.1
58
176
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
4.0
16.0
46
119
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.2
14.8
61
201
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
12.8
14.4
25
20
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
6.8
14.1
22
33
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
13.6
346
2354
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
14.9
13.6
22
15
52411, ,
ICD-8 Finland
+∞
13.6
13
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
13.0
376
2638
K01.0
ICD-10 Finland
Embedded teeth
3.7
12.8
41
115
EB1WA, ,
NOMESCO Finland
10.6
12.8
24
23
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
12.7
141
741
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
131.5
12.5
13
*
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
23.2
11.6
16
7
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
11.2
11.6
21
19
4839
FHL
Other measure in this category
+∞
11.5
11
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
11.4
414
3049
EB1S1
NOMESCO Finland
Photography of teeth
8.4
11.3
24
29
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
11.1
833
7226
EG1DG
NOMESCO Finland
Very extensive MRI examination of mandibular joint with high intensity magnet
43.8
10.9
13
*
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.0
10.9
31
80
SPC10
NOMESCO Finland
Standard dental crown
4.1
10.7
29
72
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
21.7
10.7
15
7
EEC02
NOMESCO Finland
Rapid expansion of maxilla
60.6
10.6
12
*
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
4.1
10.5
29
73
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
111.1
10.4
11
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.7
10.4
57
221
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
12.2
10.4
18
15
L01BA01
ATC
methotrexate; systemic
3.1
10.1
41
134
EMAK, ,
NOMESCO Finland
2.7
10.0
53
202
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
7.5
9.7
22
30
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
55.5
9.7
11
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
9.4
339
2469
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
9.2
109
585
Z01.2
ICD-10 Finland
Dental examination
1.5
9.2
543
4377
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
4.6
9.1
21
46
EBA10
NOMESCO Finland
Operative extraction of tooth
1.7
9.0
179
1125
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
9.0
783
6819
K03.30
ICD-10 Finland
Internal granuloma of pulp
9.6
8.8
17
18
K07.61
ICD-10 Finland
Cracking jaw joint
3.0
8.7
38
130
SCA01
NOMESCO Finland
Preventive oral health care, short
1.5
8.7
386
2929
G47.3
ICD-10 Finland
Sleep apnoea
1.6
8.7
248
1709
R51.81
ICD-10 Finland
Facial pain NOS
3.1
8.6
36
120
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.8
8.6
42
153
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
8.6
69
320
P01BA02
ATC
hydroxychloroquine; oral
2.1
8.5
84
422
K07.02
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
8.3
8
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
8.3
336
2495
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
9.5
8.3
16
17
L04AA13
ATC
[U] leflunomide
3.3
8.3
30
92
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.2
258
1816
ECA50
NOMESCO Finland
Periodontal flap surgery
4.6
8.1
19
42
SJE90
NOMESCO Finland
Orthodontic finishing
8.2
8.1
17
21
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.6
8.1
46
182
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
17.3
8.1
12
7
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
7.9
83
426
G44.2
ICD-10 Finland
Tension-type headache
1.7
7.9
157
985
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
13.1
7.9
13
10
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
7.9
395
3056
J34.2
ICD-10 Finland
Deviated nasal septum
2.2
7.8
67
319
T84.62
ICD-10 Finland
Osteitis associated with dental implants
9.5
7.8
15
16
-, ,
ICD-10 Finland
3.6
7.7
25
71
Z47.0
ICD-10 Finland
Follow-up care involving removal of fracture plate and other internal fixation device
7.5
7.7
17
23
N41.9
ICD-10 Finland
Inflammatory disease of prostate, unspecified
4.6
7.7
18
40
R06.5
ICD-10 Finland
Mouth breathing
1.9
7.6
103
579
H02AB06
ATC
prednisolone; systemic
1.4
7.5
443
3524
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.5
505
4118
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
7.7
7.4
16
21
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
8.4
7.3
15
18
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
9.4
7.3
14
15
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
4.3
7.2
18
42
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.1
353
2713
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
7.0
107
624
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
7.0
266
1943
M01CB01
ATC
sodium aurothiomalate; parenteral
6.4
7.0
17
27
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
5.9
6.9
18
31
R01AD09
ATC
mometasone; nasal
1.4
6.9
478
3896
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
7.6
6.9
15
20
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.2
6.9
27
87
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
6.8
139
879
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
40.3
6.8
8
*
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
40.3
6.8
8
*
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
40.3
6.8
8
*
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
40.3
6.8
8
*
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
40.3
6.8
8
*
SPF20
NOMESCO Finland
Temporary relining of dentures
7.9
6.6
14
18
K07.68
ICD-10 Finland
Other disorders of the jaw joint
5.5
6.6
18
33
OIKK, ,
NOMESCO Finland
2.2
6.5
51
234
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
6.5
199
1387
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.4
710
6233
7849C
ICD-9 Finland
Symptoms involving head and neck, Other symptoms involving head and neck[KUORSAUS]
14.4
6.4
10
7
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.4
218
1553
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.9
6.3
28
97
ZXE00
NOMESCO Finland
One hour or less
1.4
6.3
364
2863
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.3
247
1810
K07.28
ICD-10 Finland
Another anomaly in the relationship between the dental arches
18.1
6.3
9
5
4346
FHL
Jaw joint plastic (graft, ectomy)
+∞
6.3
6
*
52499
ICD-8 Finland
Dento-facial anomalies including malocclusion, Other and unspecified
+∞
6.3
6
*
4319
FHL
Other measure in this category
+∞
6.3
6
*
ECB10
NOMESCO Finland
Reconstruction of gingiva
26.8
6.2
8
*
ZXA00
NOMESCO Finland
Right side
1.5
6.2
215
1536
K07.6
ICD-10 Finland
Temporomandibular joint disorders
5.1
6.2
18
36
SPB20
NOMESCO Finland
Temporary bridge
7.7
6.1
13
17
UJF32
NOMESCO Finland
Coloscopy
1.5
6.1
211
1505
J01DA01
ATC
[U] cefalexin
1.4
6.1
583
4976
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
4.1
6.1
16
39
N06AB10
ATC
escitalopram; oral
1.5
6.1
229
1663
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.1
386
3084
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
6.0
47
216
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.0
367
2911
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
563
4334
1.63
13.58
11.9
10.8
0.01
0.00
e9/l
0.38
479
3549
618
4950
1.58
12.00
4.2
3.4
10.66
6.41
estimate
0.15
157
981
365
2615
1.60
11.27
4.2
3.5
0.01
0.01
estimate
0.02
143
929
606
4901
1.54
10.75
4.3
3.4
0.01
0.00
estimate
0.39
153
979
613
4980
1.54
10.57
4.3
3.4
0.00
0.01
estimate
1.08
144
923
835
7404
1.57
8.55
5.3
4.3
14.53
14.53
pmol/l
0.01
787
6890
475
3768
1.47
8.49
4.2
3.2
3.74
0.02
estimate
0.50
135
817
794
6968
1.53
8.47
8.9
8.2
76.30
80.26
u/l
2.07
760
6653
677
5784
1.46
7.98
4.6
4.0
128.62
743.16
e6/l
0.75
13
82
648
5498
1.45
7.87
10.4
10.2
3.90
3.96
e9/l
0.26
564
4809
780
6876
1.49
7.63
5.2
4.3
9.73
10.06
mm/h
0.34
740
6502
464
3738
1.42
7.29
5.1
5.4
36.89
36.74
g/l
0.24
442
3543
321
2444
1.45
6.76
3.6
3.2
0.34
0.34
e6/l
0.01
253
1743
514
4260
1.40
6.66
6.3
7.9
1.21
1.21
mmol/l
0.13
451
3717
259
1907
1.47
6.45
2.8
2.6
5.28
6.38
e6/l
0.66
236
1733
360
2819
1.42
6.44
3.6
3.2
32.70
70.57
e6/l
0.69
291
2112
53
249
2.19
6.42
1.3
1.2
—
—
—
0
0
561
4759
1.37
6.11
3.7
3.1
105.70
105.31
ug/l
0.02
538
4515
150
994
1.59
6.07
2.6
2.3
373.38
374.58
nmol/l
0.03
140
938
52
250
2.13
5.96
1.3
1.2
—
—
—
0
0
392
3157
1.38
5.81
3.3
3.2
65.52
58.49
ng/l
0.07
240
1961
307
2389
1.40
5.55
1.7
1.7
—
—
—
0
0
53
984
0.51
5.40
4.2
4.3
30.88
31.34
%
0.10
41
690
282
2172
1.40
5.39
2.0
2.0
1.12
1.12
mg/l
0.01
214
1651
62
332
1.92
5.33
1.6
1.5
0.13
0.05
iu/ml
—
7
40
101
631
1.66
5.18
2.9
3.7
1.23
1.23
mmol/l
0.30
89
545
886
8214
1.45
5.00
19.2
16.9
13.40
13.42
%
0.19
881
8118
133
899
1.55
4.93
4.2
5.1
246.66
242.63
u/l
0.12
125
864
300
2375
1.36
4.78
4.5
4.4
91.29
92.89
%
0.57
291
2326
133
907
1.53
4.74
5.8
5.6
—
—
—
0
0
287
2259
1.37
4.73
2.6
2.2
2.70
2.72
mg/l
0.08
254
1971
496
4243
1.31
4.61
2.8
2.6
74.86
74.30
nmol/l
0.18
467
3932
343
2786
1.34
4.59
3.6
2.8
1.83
0.02
estimate
0.50
138
794
79
478
1.70
4.59
2.0
1.7
317.38
296.02
mu/l
0.18
72
436
983
9354
1.59
4.41
16.6
13.7
21.43
21.98
mg/l
0.20
809
7505
924
8693
1.45
4.26
6.1
5.2
1.84
1.83
mu/l
0.03
877
8201
292
2341
1.34
4.21
1.5
1.5
2.21
2.28
g/l
0.28
188
1501
90
577
1.61
4.20
1.4
1.3
—
—
—
0
0
246
1925
1.36
4.16
1.4
1.3
19.60
27.90
iu/ml
1.50
84
572
981
9350
1.56
4.14
17.0
15.4
3.94
3.95
mmol/l
0.13
970
9168
120
828
1.51
4.06
2.9
3.0
9.87
10.39
g/l
1.05
109
776
979
9333
1.54
4.05
16.9
15.2
139.73
139.72
mmol/l
0.04
971
9178
176
1313
1.41
3.96
2.3
2.6
2.43
2.39
g/l
0.58
160
1219
350
2904
1.30
3.92
2.9
2.7
55.01
60.84
u/l
0.66
328
2729
178
1335
1.40
3.89
2.4
2.6
30.26
29.36
s
0.98
172
1302
320
2626
1.31
3.88
2.1
2.2
190.77
209.55
u/l
0.22
304
2506
42
222
1.93
3.82
4.2
4.1
1.44
1.38
mmol/l
0.13
42
216
588
5235
1.27
3.70
5.0
5.4
6.47
6.54
mmol/l
0.36
560
4929
441
3792
1.28
3.69
6.0
7.5
1.21
1.21
mmol/l
0.76
414
3540
213
1665
1.35
3.59
2.3
2.2
—
—
—
0
0
535
4722
1.26
3.57
6.9
7.0
10.78
11.35
umol/l
0.89
519
4514
65
403
1.65
3.50
1.8
1.6
11.18
8.69
u/l
0.61
43
327
275
2239
1.31
3.48
4.5
3.3
1.02
1.71
kg/l
0.50
187
1463
423
3651
1.26
3.35
2.1
1.9
98.53
97.10
pmol/l
0.26
241
1941
197
1542
1.34
3.28
3.1
2.7
2.43
2.43
mmol/l
0.21
182
1393
182
1413
1.35
3.20
2.4
2.7
15.67
14.06
umol/l
1.94
169
1327
186
1461
1.33
3.02
2.7
2.7
116.03
102.28
ug/g
0.28
155
1177
313
2638
1.26
2.97
1.5
1.4
0.91
1.59
u/ml
1.47
91
715
78
530
1.51
2.89
2.8
2.4
4590.49
5572.96
u/l
0.17
31
214
33
178
1.88
2.89
3.0
2.4
63.88
108.82
ug/min
0.41
17
109
58
369
1.60
2.87
1.5
1.5
—
—
—
0
0
155
1196
1.35
2.84
2.4
2.7
25.88
23.90
%
0.96
142
1127
83
574
1.48
2.83
1.9
1.7
—
—
—
0
0
190
1511
1.31
2.83
3.5
2.8
1.03
0.92
e6/l
0.19
108
763
922
8801
1.33
2.77
14.8
12.6
88.82
88.38
ml/min/173m2
0.30
868
7991
18
78
2.33
2.75
2.0
2.9
—
—
—
0
0
276
2310
1.26
2.75
2.4
2.8
325.92
335.10
umol/l
0.83
259
2097
32
174
1.86
2.75
1.5
1.6
—
—
—
0
0
91
652
1.43
2.61
3.6
3.6
4.54
4.65
pmol/l
0.51
83
586
347
2997
1.23
2.59
3.2
3.5
2.36
2.36
mmol/l
0.05
328
2781
1054
10337
1.96
2.59
24.5
20.8
255.80
256.30
e9/l
0.09
1049
10168
17
74
2.32
2.59
2.2
1.6
—
—
—
0
0
44
269
1.66
2.57
1.4
1.5
290.18
298.84
ug/g
0.11
30
156
202
1643
1.28
2.54
1.9
1.7
453.03
36421482.29
pmol/l
1.90
175
1425
38
224
1.72
2.53
1.9
1.4
—
—
—
0
0
40
240
1.69
2.50
2.0
1.7
—
—
—
0
0
1054
10344
1.93
2.47
24.5
20.7
4.57
4.58
e12/l
0.13
1049
10150
1054
10346
1.92
2.44
24.5
20.8
6.49
6.64
e9/l
1.80
1048
10145
185
1500
1.28
2.38
4.1
4.6
0.84
0.82
mmol/l
1.82
172
1440
214
1768
1.26
2.36
1.4
1.3
6.15
10.17
u/ml
0.63
109
708
144
1132
1.31
2.34
1.8
1.7
1271.83
1178.45
nmol/l
0.58
114
867
189
1541
1.27
2.33
2.4
2.1
—
—
—
0
0
267
2281
1.23
2.17
1.8
1.6
20.54
20.23
nmol/l
0.14
241
1988
108
825
1.34
2.15
1.3
1.2
116.98
136.66
u/ml
0.23
48
329
47
307
1.56
2.14
1.5
2.2
1.28
1.40
g/l
0.32
41
271
56
382
1.49
2.10
5.0
2.7
1.02
1.02
ratio
0.61
49
355
90
672
1.37
2.08
2.5
2.3
0.13
0.24
e6/l
0.97
85
637
910
8747
1.26
2.04
4.9
4.5
5.80
5.83
mmol/l
0.27
866
8194
46
305
1.53
1.98
1.2
1.1
2.59
2.20
u/ml
0.10
29
177
410
3679
1.18
1.95
12.3
10.1
1.19
1.14
inr
1.07
347
3035
383
3417
1.19
1.95
3.6
3.5
31.31
31.41
u/l
0.02
371
3247
30
180
1.69
1.93
4.8
2.8
1.33
1.48
mmol/l
0.66
30
175
70
511
1.40
1.87
2.8
3.1
111.81
131.28
ng/l
0.37
62
468
117
924
1.30
1.87
3.0
2.3
12.11
13.24
nmol/l
0.84
106
860
16
302
0.52
1.85
2.4
1.9
—
—
—
0
0
139
1125
1.27
1.84
2.4
3.4
7.72
7.32
umol/l
0.07
119
988
733
6931
1.18
1.78
3.5
3.4
—
—
—
0
0
41
275
1.51
1.71
1.1
1.1
7.77
6.98
u/ml
0.07
24
164
110
873
1.29
1.71
7.9
10.7
1.58
0.74
mmol/l
1.03
86
738
1008
9854
1.36
1.71
13.4
11.4
27.77
27.50
u/l
0.19
989
9652
11
48
2.31
1.71
1.2
1.1
204.36
529.86
u/l
0.75
11
42
30
188
1.61
1.67
1.1
1.3
2.00
4.18
u/ml
0.83
13
66
5
14
3.58
1.61
1.4
2.4
—
—
—
0
0
21
121
1.75
1.59
1.5
1.3
—
—
—
0
0
39
264
1.50
1.58
1.1
1.1
0.61
1.26
u/ml
0.51
23
127
29
184
1.59
1.55
1.1
1.3
7.36
4.92
u/ml
0.23
11
78
88
689
1.30
1.53
1.6
1.5
—
—
—
0
0
23
138
1.68
1.52
3.9
3.4
20.69
23.70
nmol/l
0.80
23
132
881
8503
1.20
1.51
6.1
5.6
38.45
38.48
mmol/mol
0.02
840
8112
37
252
1.48
1.47
2.1
1.8
—
—
—
0
0
23
140
1.66
1.46
1.1
1.3
—
—
—
0
0
33
221
1.51
1.42
1.4
1.2
—
—
—
0
0
48
347
1.40
1.41
1.5
1.5
—
—
—
0
0
15
81
1.86
1.40
2.5
4.5
14.40
12.43
index
—
10
61
106
861
1.26
1.40
2.0
2.1
—
—
—
0
0
38
264
1.46
1.38
1.3
1.2
57.36
56.48
u/ml
—
5
25
237
2088
1.17
1.37
3.3
3.2
477.85
780.96
ng/l
2.87
202
1730
38
266
1.44
1.34
2.3
2.9
—
—
—
0
0
81
641
1.29
1.33
1.5
1.5
19.32
25.49
iu/l
0.93
61
536
6
24
2.51
1.30
1.7
1.2
—
—
—
0
0
24
153
1.58
1.29
1.4
1.4
—
—
—
0
0
24
153
1.58
1.29
1.4
1.4
—
—
—
0
0
17
280
0.60
1.28
2.2
1.7
—
—
—
0
0
894
8675
1.18
1.26
4.6
4.0
1.29
1.30
mmol/l
0.18
847
8185
120
1002
1.22
1.25
2.3
2.2
—
—
—
0
0
33
228
1.46
1.25
1.5
1.5
0.54
0.31
nmol/l
0.77
22
181
9
45
2.01
1.23
1.4
2.1
—
—
—
0
0
9
45
2.01
1.23
1.4
2.1
—
—
—
0
0
86
698
1.25
1.17
2.5
2.4
25.14
18.46
au/ml
—
9
81
27
182
1.50
1.16
1.1
1.1
—
—
—
0
0
26
175
1.50
1.13
3.7
3.5
9.05
7.75
pmol/l
0.22
26
175
21
318
0.65
1.13
1.4
1.4
—
—
—
0
0
32
225
1.44
1.13
1.3
1.1
3.57
4.60
u/ml
0.18
23
116
14
80
1.76
1.13
4.4
2.5
1.20
1.20
mmol/l
0.09
14
80
936
9138
1.19
1.11
5.3
4.8
4.72
4.72
mmol/l
0.04
899
8712
10
51
1.97
1.11
2.2
2.4
868.80
571.30
ml
—
5
30
14
81
1.74
1.09
4.4
2.5
3.97
3.99
mmol/l
0.06
14
81
14
81
1.74
1.09
4.4
2.5
106.64
105.68
mmol/l
0.37
14
81
52
400
1.32
1.08
1.6
1.7
—
—
—
0
0
160
1395
1.17
1.07
3.7
3.0
4.49
2.44
e6/l
0.71
80
650
75
609
1.25
1.04
2.0
3.0
67.12
67.40
g/l
0.13
68
576
22
323
0.67
1.04
1.4
1.4
1.78
1.20
ratio
—
9
204
22
323
0.67
1.04
1.4
1.4
1.44
1.23
ratio
—
9
204
22
323
0.67
1.04
1.4
1.4
0.93
0.94
ratio
—
9
204
56
440
1.29
1.01
1.5
1.8
5.26
4.65
iu/ml
0.12
19
92
5
106
0.47
1.01
1.8
1.5
—
—
—
0
0
5
106
0.47
1.01
1.8
1.5
—
—
—
0
0
13
76
1.72
0.99
1.2
1.5
161.00
172.14
pmol/l
0.17
13
76
36
267
1.36
0.97
1.3
1.1
0.76
1.93
u/ml
1.58
21
148
37
489
0.75
0.96
1.2
1.2
0.86
0.89
g/l
0.45
37
489
456
4285
1.11
0.96
2.7
2.8
—
—
estimate
—
0
0
941
9213
1.17
0.96
5.7
5.3
2.80
2.80
mmol/l
0.07
903
8757
25
174
1.45
0.95
1.6
1.8
—
—
—
0
0
27
192
1.42
0.93
1.6
1.4
31.00
23.13
u/l
0.53
21
162
26
184
1.42
0.92
1.2
1.1
—
—
—
0
0
104
888
1.19
0.91
4.6
5.2
2.35
1.78
mmol/l
0.95
95
758
106
908
1.19
0.89
2.6
2.6
37.61
94.21
u/l
0.53
94
764
5
105
0.47
0.89
1.8
1.5
—
—
—
0
0
709
6839
1.11
0.86
3.7
3.5
49.23
46.62
u/l
0.33
680
6561
6
111
0.54
0.83
1.7
1.4
—
—
—
0
0
6
111
0.54
0.83
1.7
1.4
—
—
—
0
0
6
114
0.52
0.83
12.8
1.7
—
—
—
0
0
11
65
1.70
0.82
1.4
1.4
—
—
—
0
0
11
65
1.70
0.82
1.5
1.6
—
1020533.17
—
0
6
37
476
0.77
0.82
1.2
1.1
1.45
1.52
g/l
1.28
37
476
84
712
1.19
0.81
1.8
2.5
78.55
73.27
ml/min/173m2
0.42
33
296
31
233
1.34
0.80
2.8
3.6
2.73
2.22
index
0.13
15
135
17
114
1.50
0.79
8.4
6.0
11.15
10.78
mg/l
0.18
17
105
378
4016
0.91
0.78
2.0
1.9
1.34
1.40
mmol/l
0.78
324
3515
26
349
0.74
0.78
1.3
1.5
76.28
64.98
ug/l
0.41
20
298
110
960
1.16
0.76
1.7
1.9
—
—
—
0
0
6
34
1.77
0.76
1.0
1.7
—
—
—
0
0
6
34
1.77
0.76
1.5
2.2
123.50
120.67
ng/l
—
6
34
9
55
1.64
0.73
10.1
3.2
527.33
624.69
u/ml
—
9
55
9
56
1.61
0.72
1.3
1.8
—
—
—
0
0
9
56
1.61
0.72
1.0
1.0
2326.78
1671.79
miu/ml
—
9
56
6
110
0.54
0.72
1.7
1.4
—
—
—
0
0
40
318
1.27
0.71
1.2
1.1
3.68
3.73
—
5
53
167
1510
1.13
0.70
2.2
1.8
1.42
1.43
%
0.11
141
1344
22
160
1.38
0.70
2.5
3.4
29.91
26.72
mg/l
0.11
15
107
10
61
1.65
0.68
2.7
4.9
0.70
0.82
index
—
10
61
16
110
1.46
0.68
1.3
1.9
—
—
—
0
0
5
27
1.86
0.68
2.4
4.1
7.98
10.46
kpa
—
5
27
5
27
1.86
0.68
2.4
4.1
5.27
4.77
kpa
—
5
27
11
69
1.60
0.68
1.2
1.2
—
—
—
0
0
112
991
1.15
0.66
1.8
1.9
—
—
—
0
0
25
189
1.33
0.65
1.2
1.1
0.76
0.33
u/ml
—
10
64
43
352
1.23
0.62
1.2
1.3
—
—
—
0
0
8
49
1.64
0.62
1.0
1.1
—
—
—
0
0
8
49
1.64
0.62
1.0
1.1
—
—
—
0
0
5
30
1.67
0.61
1.0
1.7
—
—
—
0
0
8
51
1.57
0.60
1.0
1.2
11.75
13.55
u/l
—
8
42
30
236
1.28
0.60
1.3
1.8
3.96
9.73
e6/l
0.85
24
172
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
8
52
1.54
0.59
1.0
1.2
64.63
71.68
u/l
—
8
44
259
2422
1.09
0.59
4.8
4.3
1.79
1.79
ug/l
0.01
237
2224
20
265
0.75
0.59
1.4
1.8
—
—
—
0
0
91
802
1.15
0.59
2.6
3.0
—
—
—
0
0
926
9117
1.11
0.58
5.2
4.7
1.47
1.45
mmol/l
0.57
888
8649
30
239
1.26
0.55
1.3
1.9
132.08
942.67
e6/l
0.77
25
180
23
177
1.31
0.55
1.4
1.6
—
—
—
0
0
12
82
1.47
0.54
4.0
3.7
—
—
—
0
0
6
38
1.58
0.54
1.8
2.5
—
—
—
0
0
18
134
1.35
0.53
1.0
1.1
—
—
—
0
0
26
205
1.27
0.53
1.2
1.1
4.72
8.18
u/ml
0.66
15
92
6
40
1.50
0.51
1.2
1.2
87.50
107.32
%
—
6
34
37
306
1.22
0.51
1.8
2.0
3.07
3.76
iu/l
0.37
19
128
13
92
1.42
0.50
1.0
1.1
—
—
—
0
0
13
92
1.42
0.50
1.0
1.1
—
—
—
0
0
6
41
1.47
0.50
1.3
1.2
0.30
0.29
g/l
—
6
35
6
41
1.47
0.50
1.0
1.0
—
—
—
0
0
27
216
1.26
0.49
1.1
1.2
—
—
—
0
0
28
226
1.25
0.48
1.3
1.6
65.33
54.07
ug/l
0.70
28
226
39
460
0.84
0.45
1.3
1.3
143.28
236.06
miu/ml
1.59
18
226
35
292
1.21
0.45
1.7
1.7
—
—
—
0
0
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
6
92
0.65
0.42
1.3
1.1
—
68.00
—
0
7
13
96
1.36
0.41
1.1
1.4
6.76
3.29
u/ml
—
6
51
46
398
1.16
0.41
1.3
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
3.3
—
0.56
—
0
16
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
8.17
—
0
6
5
34
1.47
0.40
1.0
1.1
33.68
43.66
iu/ml
—
5
34
13
97
1.34
0.39
1.0
1.1
—
—
—
0
0
13
97
1.34
0.39
1.0
1.1
—
—
—
0
0
131
1214
1.09
0.39
5.9
7.3
1.06
1.07
mmol/l
0.14
118
1145
0
19
0.00
0.39
0.0
7.6
—
11.07
—
0
19
0
19
0.00
0.39
0.0
1.8
—
2.04
—
0
8
5
37
1.35
0.37
1.0
1.4
87.20
96.62
%
—
5
37
12
90
1.34
0.36
1.2
1.1
176.00
241.47
mg/l
2.51
12
75
5
79
0.63
0.35
1.2
1.8
—
—
—
0
0
5
79
0.63
0.35
1.2
1.8
—
—
—
0
0
5
79
0.63
0.35
1.2
1.8
—
—
—
0
0
19
154
1.24
0.34
1.1
1.3
—
—
—
0
0
6
45
1.34
0.33
1.2
1.1
—
—
—
0
0
6
46
1.31
0.33
1.0
1.3
—
—
—
0
0
24
201
1.20
0.32
2.7
2.1
138.67
133.07
g/l
0.36
18
167
6
47
1.28
0.32
1.5
1.5
4.82
6.18
mmol/l
—
6
47
128
1366
0.93
0.32
2.0
2.0
3.59
3.53
ratio
0.19
91
1067
13
101
1.29
0.31
1.0
1.1
—
—
—
0
0
23
273
0.84
0.31
1.3
1.3
—
—
—
0
0
31
267
1.17
0.31
1.3
1.7
388.97
481.88
mg/l
1.84
31
252
14
111
1.26
0.30
1.1
1.2
—
—
—
0
0
10
130
0.77
0.29
1.0
1.1
—
—
—
0
0
12
151
0.79
0.28
2.3
2.1
—
2752.00
—
0
5
12
94
1.28
0.28
1.3
1.4
2.00
1.47
nmol/l
0.76
12
87
50
553
0.90
0.28
2.4
1.7
0.36
0.33
mg/l
0.16
21
271
8
64
1.25
0.27
1.6
2.6
—
—
—
0
0
11
86
1.28
0.26
1.5
1.9
—
—
—
0
0
35
310
1.13
0.26
1.4
1.2
5.48
11.49
u/ml
—
5
42
23
197
1.17
0.26
1.2
3.6
1.29
1.75
ratio
0.79
16
105
18
151
1.20
0.25
1.8
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
25
217
1.16
0.24
7.4
4.3
0.55
0.34
iu/ml
0.98
12
109
19
161
1.18
0.24
5.1
4.0
141.39
263.16
u/ml
0.27
19
149
24
275
0.87
0.23
1.5
1.9
—
—
—
0
0
230
2220
1.05
0.23
2.2
2.3
—
—
—
0
0
12
97
1.24
0.23
1.4
2.0
—
—
—
0
0
5
40
1.25
0.22
1.2
1.2
—
—
—
0
0
171
1642
1.05
0.21
4.1
3.5
438.79
485.54
ng/l
0.07
131
1136
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
7.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
8
105
0.76
0.21
1.5
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
21
183
1.15
0.20
2.3
3.1
3.88
8.40
umol/l
1.68
14
135
0
14
0.00
0.20
0.0
6.4
—
122771.43
—
0
7
0
14
0.00
0.20
0.0
6.2
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
137.00
231.59
iu/ml
—
6
48
6
48
1.25
0.20
1.5
1.6
0.70
0.50
e9/l
—
6
48
6
49
1.23
0.20
1.0
1.4
—
—
—
0
0
9
114
0.79
0.20
1.0
1.1
—
—
—
0
0
19
165
1.15
0.19
1.3
1.2
—
—
—
0
0
48
445
1.08
0.18
1.9
1.8
4.81
3.67
mg/l
0.24
34
320
5
69
0.72
0.17
1.0
1.2
7.40
8.67
mm/h
—
5
69
12
101
1.19
0.16
1.1
1.2
49.58
56.35
u/l
0.50
12
92
8
69
1.16
0.16
1.0
1.4
62.75
75.71
umol/l
—
8
69
16
183
0.87
0.16
1.1
1.1
1.00
1.83
eliau/ml
—
9
82
169
1637
1.04
0.15
1.6
1.5
—
—
—
0
0
6
77
0.78
0.15
1.0
1.5
—
—
—
0
0
28
255
1.10
0.15
1.4
1.6
129.00
143.67
au/ml
—
5
89
43
461
0.93
0.15
1.9
1.7
—
—
—
0
0
9
83
1.09
0.14
1.1
1.2
100.00
113.27
pmol/l
—
9
83
47
440
1.07
0.14
1.6
1.8
—
—
—
0
0
11
93
1.18
0.14
1.3
1.2
36.00
34.33
mg/l
0.06
11
73
61
577
1.06
0.14
1.2
1.2
—
0.90
—
0
5
40
373
1.08
0.13
1.8
1.7
8.51
9.13
u/ml
—
10
93
191
1960
0.97
0.13
4.3
3.7
21.88
21.54
%
0.13
79
788
21
190
1.11
0.12
1.3
1.3
—
—
—
0
0
34
316
1.08
0.12
2.4
3.4
2612.75
1032.51
u/ml
0.29
27
273
43
404
1.07
0.12
1.5
1.5
—
—
—
0
0
12
137
0.87
0.12
1.4
1.8
—
—
—
0
0
19
172
1.11
0.11
1.4
2.0
—
—
—
0
0
21
229
0.92
0.11
1.5
1.6
—
—
—
0
0
73
759
0.96
0.10
4.4
4.6
3.51
16.53
ug/l
1.23
55
604
5
46
1.09
0.09
1.2
2.4
77.20
88.01
ug/l
—
5
46
61
586
1.04
0.09
2.7
4.7
1.75
1.64
mmol/l
0.15
41
427
18
196
0.92
0.09
1.4
1.5
—
—
—
0
0
14
126
1.11
0.09
5.4
4.0
1.07
1.32
%
0.21
14
118
6
56
1.07
0.08
1.3
1.7
—
—
—
0
0
59
613
0.96
0.08
1.4
1.6
936.00
988.26
mu/l
0.27
48
526
6
57
1.05
0.08
1.0
1.3
—
19.70
—
0
10
10
88
1.14
0.08
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
1.4
1.7
—
—
—
0
0
66
640
1.03
0.07
2.8
4.8
77.68
77.95
ng/l
0.01
60
582
45
434
1.04
0.06
1.5
1.4
—
—
—
0
0
65
633
1.03
0.05
1.1
1.0
—
—
—
0
0
11
101
1.09
0.04
1.1
1.1
—
—
—
0
0
12
111
1.08
0.04
1.0
1.4
—
—
—
0
0
17
161
1.06
0.03
1.0
1.1
1.48
1.45
g/l
0.11
17
149
29
300
0.97
0.03
1.3
1.5
284.90
224.35
u/ml
0.58
21
171
13
138
0.94
0.02
1.5
1.9
—
—
—
0
0
23
238
0.97
0.02
1.6
1.6
—
—
—
0
0
31
318
0.97
0.02
1.2
1.4
—
29.54
—
0
5
20
193
1.04
0.01
1.6
1.6
—
—
—
0
0
20
206
0.97
0.00
3.5
3.8
35.55
34.28
umol/l
0.10
20
194
266
2653
1.00
0.00
4.1
4.1
7.70
8.51
mg/mmol
0.14
160
1673
26
254
1.02
0.00
6.7
8.0
1853.00
332.65
iu/ml
—
5
34
10
96
1.04
0.00
1.1
1.1
284.90
281.84
mg/l
—
10
86
10
96
1.04
0.00
1.4
1.1
—
—
—
0
0
15
152
0.99
0.00
1.5
1.6
—
—
—
0
0
134
1342
1.00
0.00
1.9
1.9
—
—
—
0
0
307
3072
1.00
0.00
3.7
3.5
8.34
8.27
mmol/l
0.10
269
2678
149
1493
1.00
0.00
2.9
2.7
0.73
0.68
ug/l
0.28
93
829
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
26.90
—
0
5
6
65
0.92
0.00
4.3
7.8
—
66.00
—
0
19
0
6
0.00
0.00
0.0
1.2
—
11.83
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
58.86
—
0
7
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
8
89
0.90
0.00
1.0
1.3
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
62
0.97
-0.00
3.5
3.1
468.00
1030.84
mg
—
6
62
5
50
1.00
-0.00
1.2
1.2
—
—
—
0
0
7
78
0.90
-0.00
1.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
10.33
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
59
0.85
-0.00
1.2
1.1
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.1
—
—
—
0
0
9
90
1.00
-0.00
1.0
1.3
—
—
—
0
0
102
1020
1.00
-0.00
1.7
1.7
3.42
3.47
mmol/l
0.16
66
726
Mortality – FinRegistry
↥Association
Association between endpoint K11_MAJOR_ANOMALI_JAW_SIZE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_MAJOR_ANOMALI_JAW_SIZE | 1.127 [0.86, 1.48] | 0.383 |
| Birth year | 0.992 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 4789 females with K11_MAJOR_ANOMALI_JAW_SIZE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_MAJOR_ANOMALI_JAW_SIZE | 0.887 [0.69, 1.14] | 0.353 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 4404 males with K11_MAJOR_ANOMALI_JAW_SIZE died.
Mortality risk
Mortality risk for people of age
years, who have K11_MAJOR_ANOMALI_JAW_SIZE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.115% | 0.146% |
| 5 | 0.521% | 1.032% |
| 10 | 1.407% | 2.595% |
| 15 | 2.921% | 4.935% |
| 20 | 5.07% | 8.565% |
Relationships between endpoints
↥Index endpoint: K11_MAJOR_ANOMALI_JAW_SIZE – Major anomalies of jaw size
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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