Food allergy

FOOD_ALLERGY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L23.6
  • Cause of death: ICD-10 L23.6

2 out of 7 registries used, show all original rules.

117

4. Check minimum number of events

None

117

5. Include endpoints

None

117

6. Filter based on genotype QC (FinnGen only)

109

Control definitions (FinnGen only)

Control exclude
ASTHMA_ALLERG

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L23
Name in latin
Eczema allergicum ex contactu nutrimentorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1444 806 635
Only index persons 1161 681 480
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 15.11 23.09 4.90
Only index persons 19.59 26.47 9.83

-FinnGen-

Key figures

All Female Male
Number of individuals 109 83 26
Unadjusted period prevalence (%) 0.03 0.03 0.01
Median age at first event (years) 35.60 37.38 29.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
112
Matched controls
1120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L23.6
ICD-10 Finland
Allergic contact dermatitis due to food in contact with skin
+∞
161.6
112
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
12.5
38.2
50
68
XQ800
NOMESCO Finland
Prick test
11.0
28.6
37
48
C01CA24
ATC
epinephrine; parenteral
9.0
23.3
35
54
L20.0
ICD-10 Finland
Besnier prurigo
7.1
20.6
40
81
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
5.9
11.3
23
47
E0000UV, ,
ATC
3.9
10.9
73
365
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
8.8
10.3
22
30
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
44.3
10.2
12
*
E000002, ,
ATC
4.3
9.8
31
92
XQ802
NOMESCO Finland
Epicutan test
9.3
9.3
19
24
D07AC13
ATC
mometasone; topical
3.4
8.9
46
190
R06AE09
ATC
levocetirizine; oral
4.0
8.7
30
94
E000001, ,
ATC
3.3
7.9
40
161
H02AB06
ATC
prednisolone; systemic
3.1
7.8
63
332
T78.4
ICD-10 Finland
Allergy, unspecified
6.3
7.3
19
35
J45.9
ICD-10 Finland
Asthma, unspecified
3.4
7.2
31
112
J30.3
ICD-10 Finland
Other allergic rhinitis
7.3
6.9
16
25
R06AX27
ATC
desloratadine; oral
2.8
6.7
52
262
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
15.5
6.5
10
7
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.3
6.4
18
48
D07AD01
ATC
clobetasol; topical
3.4
6.3
27
97
R06AE07
ATC
cetirizine; oral
2.7
6.2
65
380
D07AB08
ATC
desonide; topical
3.5
6.0
24
82

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
0
+∞
5.24
1.2
0.0
0.55
—
u/ml
—
5
0
14
31
5.01
4.75
1.4
1.3
1.30
2.06
u/ml
—
9
21
8
16
5.29
3.11
3.9
2.4
1.43
1.09
mmol/l
—
8
16
7
13
5.66
2.91
6.6
2.8
—
—
—
0
0
5
6
8.64
2.77
1.2
1.2
—
—
—
0
0
10
30
3.56
2.68
4.5
2.3
24.56
24.05
mmol/l
—
10
30
7
15
4.90
2.64
4.3
2.3
6.20
6.58
mmol/l
—
7
15
11
38
3.10
2.49
3.5
2.7
0.72
0.58
%
1.04
11
38
17
79
2.36
2.39
2.4
1.4
381.19
394.17
u/ml
0.01
17
74
5
9
5.75
2.23
3.4
2.4
107.80
105.78
mmol/l
—
5
9
5
9
5.75
2.23
3.4
2.4
1.18
1.18
mmol/l
—
5
9
5
9
5.75
2.23
3.4
2.4
3.76
3.88
mmol/l
—
5
9
28
165
1.93
2.18
4.4
2.3
494.43
529.48
mosm/kgh2o
0.26
23
141
98
852
2.20
2.06
3.4
3.7
1.17
1.25
mmol/l
0.67
93
805
43
301
1.70
1.88
4.3
3.2
0.00
0.01
estimate
0.49
15
94
20
111
1.98
1.83
1.8
1.6
—
—
—
0
0
66
524
1.63
1.73
4.0
3.5
0.00
0.00
estimate
-0.00
17
112
52
392
1.61
1.67
4.0
3.4
0.00
0.01
estimate
0.50
15
98
66
528
1.61
1.65
4.0
3.6
0.00
0.00
estimate
-0.00
15
108
13
64
2.17
1.61
1.5
1.2
—
—
—
0
0
65
520
1.60
1.61
4.1
3.5
0.00
0.00
estimate
-0.00
17
112
8
33
2.53
1.57
1.1
1.3
—
—
—
0
0
112
1077
+∞
1.56
21.5
20.4
135.42
135.62
g/l
0.06
112
1069
112
1076
+∞
1.55
21.0
20.2
89.92
89.96
fl
0.03
112
1068
112
1076
+∞
1.55
21.2
20.7
39.71
40.55
%
0.61
112
1068
112
1076
+∞
1.55
21.1
20.2
30.04
30.05
pg
0.01
112
1068
19
110
1.88
1.55
1.8
1.7
—
—
—
0
0
64
517
1.56
1.47
6.8
6.5
0.55
0.54
e9/l
0.13
55
462
64
519
1.54
1.43
6.8
6.5
0.04
0.04
e9/l
0.44
56
462
58
465
1.51
1.34
11.7
9.4
0.00
0.00
e9/l
0.53
48
379
6
24
2.58
1.32
1.2
1.2
—
—
—
0
0
5
18
2.86
1.30
2.4
4.8
3.93
4.70
e9/l
—
5
18
65
538
1.50
1.26
7.0
6.6
1.92
2.14
e9/l
0.83
58
492
39
291
1.52
1.24
3.9
3.2
19.50
267.57
e6/l
0.57
29
219
31
220
1.57
1.23
1.7
3.6
1.02
1.02
kg/l
0.59
16
144
65
541
1.48
1.21
6.8
7.2
0.20
0.19
e9/l
0.22
58
490
32
230
1.55
1.20
1.8
1.6
19.56
21.74
nmol/l
0.40
26
204
15
89
1.79
1.14
3.5
7.9
104.27
104.84
mmol/l
0.19
15
89
18
113
1.71
1.14
1.0
1.2
—
—
—
0
0
15
90
1.77
1.10
5.4
4.2
7.38
7.38
ph
—
9
54
51
411
1.44
1.09
3.1
3.2
6.11
6.23
ph
0.36
27
221
89
800
1.55
1.05
5.0
4.6
14.37
14.52
pmol/l
0.28
84
750
104
977
1.90
1.02
15.7
13.3
18.75
19.99
mg/l
0.15
88
770
7
35
2.07
1.02
2.9
2.1
—
—
—
0
0
43
341
1.42
0.98
1.7
1.6
—
—
—
0
0
19
127
1.60
0.96
4.3
2.8
3.60
4.41
e6/l
0.15
11
65
33
251
1.45
0.94
4.3
2.8
0.34
0.29
e6/l
0.12
23
183
101
943
1.72
0.91
14.9
13.8
139.34
139.76
mmol/l
1.14
101
927
101
946
1.69
0.85
14.6
13.8
4.00
3.92
mmol/l
2.12
101
928
36
283
1.40
0.85
2.0
1.4
2.40
2.09
g/l
0.52
23
169
44
360
1.37
0.82
2.3
1.9
91.00
95.13
pmol/l
0.24
25
186
26
195
1.43
0.79
2.9
2.8
8.72
7.62
e6/l
0.08
20
174
18
125
1.52
0.79
1.2
1.1
—
—
—
0
0
5
23
2.23
0.77
1.0
1.2
—
—
—
0
0
32
251
1.38
0.76
4.2
4.7
—
—
—
0
0
5
24
2.13
0.75
3.8
6.2
—
—
—
0
0
7
38
1.90
0.75
2.3
2.2
—
4.64
—
0
8
39
319
1.34
0.71
6.7
8.0
1.05
1.08
inr
0.18
29
265
92
855
1.43
0.69
16.6
16.4
13.34
13.34
%
0.01
92
848
5
27
1.89
0.69
2.4
4.2
57.60
61.24
%
—
5
27
27
209
1.38
0.69
3.3
4.2
—
—
—
0
0
17
123
1.45
0.62
1.2
1.4
—
—
—
0
0
105
1006
1.70
0.62
12.4
11.6
—
—
—
0
0
15
106
1.48
0.61
1.2
1.4
—
—
—
0
0
20
151
1.40
0.59
1.9
1.5
496.00
489.33
titre
—
5
30
6
35
1.75
0.59
1.8
1.5
0.19
0.23
g/l
—
6
35
6
35
1.75
0.59
4.0
17.7
—
—
—
0
0
28
227
1.31
0.54
1.3
1.3
30.97
23.27
iu/ml
—
8
62
25
307
0.76
0.53
1.8
2.5
—
—
—
0
0
26
210
1.31
0.51
2.1
1.8
1.06
0.69
mg/l
0.63
21
167
7
45
1.59
0.50
2.3
1.2
—
—
—
0
0
30
252
1.26
0.44
4.4
2.9
—
—
—
0
0
64
584
1.22
0.44
9.7
10.8
3.72
3.94
e9/l
0.57
59
523
47
416
1.22
0.44
2.4
2.7
—
—
—
0
0
5
32
1.59
0.43
7.2
4.0
37.00
36.98
°c
—
5
32
41
359
1.22
0.42
1.9
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
105
1015
1.55
0.41
16.9
14.8
70.80
68.73
umol/l
0.46
105
1000
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
40
350
1.22
0.41
5.1
3.7
19.05
28.21
e6/l
0.39
30
231
37
322
1.22
0.40
6.4
6.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
41
365
1.19
0.35
5.8
8.4
1.22
1.22
mmol/l
0.00
41
342
10
74
1.39
0.33
2.3
2.0
—
—
—
0
0
18
147
1.27
0.33
1.7
4.3
0.83
0.81
mmol/l
0.28
18
136
7
51
1.40
0.32
1.7
1.9
—
—
—
0
0
7
53
1.34
0.31
1.6
1.5
—
—
—
0
0
7
55
1.29
0.30
1.6
1.6
—
—
—
0
0
35
312
1.18
0.29
1.3
1.3
5.26
1.54
u/ml
—
9
78
35
313
1.17
0.28
4.3
6.7
—
—
—
0
0
12
95
1.29
0.27
1.3
1.4
—
—
—
0
0
23
201
1.18
0.23
1.5
1.6
—
—
—
0
0
25
221
1.17
0.22
1.5
1.9
—
—
—
0
0
5
41
1.23
0.22
1.8
1.3
—
—
—
0
0
104
1018
1.30
0.22
11.0
10.6
26.09
25.90
u/l
0.05
104
999
5
42
1.20
0.22
1.6
8.9
24.06
24.46
mmol/l
—
5
42
0
10
0.00
0.21
0.0
1.5
—
92.43
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
153.38
—
0
12
30
271
1.15
0.21
1.6
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
9.93
—
0
14
24
214
1.15
0.19
5.2
3.2
23.71
60.27
mg/l
0.99
18
137
7
59
1.20
0.18
2.1
10.1
23.64
24.71
mmol/l
—
7
59
7
61
1.16
0.18
5.1
4.8
23.26
23.94
mmol/l
—
7
61
42
449
0.90
0.18
2.6
3.1
—
—
estimate
—
0
0
8
68
1.19
0.17
5.9
10.6
—
—
—
0
0
24
217
1.13
0.16
6.1
3.7
3.72
10.63
mg/mmol
1.18
16
134
11
93
1.20
0.15
2.4
3.2
—
—
—
0
0
10
118
0.83
0.15
2.0
2.1
—
—
—
0
0
15
133
1.15
0.12
1.9
2.4
—
—
—
0
0
5
43
1.17
0.10
1.2
1.7
1.40
2.58
ug/l
—
5
38
5
46
1.09
0.10
1.0
1.1
1.50
1.58
g/l
—
5
46
5
46
1.09
0.10
1.0
1.1
—
0.59
—
0
8
11
124
0.87
0.09
1.4
1.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.2
0.80
0.85
g/l
—
5
48
24
224
1.09
0.09
2.6
3.2
—
—
—
0
0
6
57
1.06
0.08
1.0
1.5
—
—
—
0
0
7
64
1.10
0.08
1.0
1.4
—
—
—
0
0
7
65
1.08
0.08
1.0
1.1
—
—
—
0
0
6
71
0.84
0.08
1.8
1.7
—
—
—
0
0
12
108
1.12
0.07
4.8
8.5
1.08
1.10
mmol/l
0.14
12
94
9
88
1.02
0.07
1.6
1.6
—
—
—
0
0
16
149
1.09
0.05
3.4
3.4
5.70
256.91
ng/l
—
10
87
18
189
0.94
0.03
1.4
1.6
—
—
—
0
0
25
241
1.05
0.03
4.9
4.1
7.41
7.40
ph
0.31
12
167
27
264
1.03
0.00
2.9
2.6
—
—
—
0
0
28
278
1.01
0.00
3.6
3.9
0.00
0.00
estimate
-0.00
16
107
34
343
0.99
0.00
1.9
2.2
—
—
—
0
0
29
285
1.02
0.00
5.0
2.8
10.10
20.34
ng/l
2.10
17
149
21
211
0.99
0.00
1.5
1.3
1.18
7.99
u/ml
1.87
12
86
5
58
0.86
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
46.18
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
130.17
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
-0.00
1.6
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
-0.00
1.6
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
90
1.00
-0.00
1.6
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
154.57
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
0.60
—
0
5
5
55
0.90
-0.00
6.6
4.9
1.23
1.22
mmol/l
—
5
48
40
400
1.00
-0.00
1.5
1.9
1.37
1.36
mmol/l
0.03
34
354
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
10.40
—
0
5
6
64
0.93
-0.00
1.5
1.9
—
—
—
0
0
5
50
1.00
-0.00
1.6
11.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
2.94
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
2259.00
—
0
5
8
85
0.94
-0.00
1.6
1.6
—
—
—
0
0
9
90
1.00
-0.00
1.6
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint FOOD_ALLERGY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have FOOD_ALLERGY.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: FOOD_ALLERGY – Food allergy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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