Calcific tendinitis

M13_CALCTENDINITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M65.2
  • Cause of death: ICD-10 M65.2

2 out of 7 registries used, show all original rules.

399

4. Check minimum number of events

None

399

5. Include endpoints

None

399

6. Filter based on genotype QC (FinnGen only)

364

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65
Name in latin
Tendinitis calcificans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2142 1286 852
Only index persons 2086 1262 824
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 50.24 50.75 49.52
Only index persons 50.18 50.65 49.47

-FinnGen-

Key figures

All Female Male
Number of individuals 364 228 136
Unadjusted period prevalence (%) 0.07 0.08 0.06
Median age at first event (years) 52.67 50.31 56.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
373
Matched controls
3730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M65.2
ICD-10 Finland
Calcific tendinitis
4503599627370496.0
307.7
372
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
53.1
125.0
73
17
M75.1
ICD-10 Finland
Rotator cuff syndrome
8.3
92.6
180
375
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
33.0
92.0
61
22
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
314.7
54.7
54
*
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
10.8
39.4
45
47
M79.6
ICD-10 Finland
Pain in limb
3.8
36.4
207
915
N02AX02
ATC
tramadol; systemic, rectal
3.6
33.6
208
958
M65.3
ICD-10 Finland
Trigger finger
12.0
32.4
34
31
NBG10
NOMESCO Finland
Acromioplastia
76.9
31.5
35
5
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
174.5
31.2
32
*
N03AX12
ATC
[U] gabapentin; oral
4.2
27.3
87
252
N03AX16
ATC
[U] pregabalin
3.5
25.8
115
418
M54.4
ICD-10 Finland
Lumbago with sciatica
3.7
24.9
96
317
M70.6
ICD-10 Finland
Trochanteric bursitis
4.2
23.3
71
198
M01AH05
ATC
etoricoxib; oral
3.3
22.9
283
1809
G56.0
ICD-10 Finland
Carpal tunnel syndrome
4.0
22.6
75
222
M03BX02
ATC
tizanidine; oral
3.2
22.0
280
1801
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.5
21.6
59
151
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
20.8
195
1056
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.1
20.3
62
172
L08
ICPC
Shoulder symptom/complaint
3.1
19.9
108
435
M01AH01
ATC
celecoxib; oral
3.3
19.8
90
326
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.6
19.6
74
238
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
24.1
19.4
27
12
M25.5
ICD-10 Finland
Pain in joint
2.7
19.3
154
762
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
20.1
18.9
28
15
M79.0
ICD-10 Finland
Rheumatism, unspecified
73.8
18.9
21
*
M02AA07
ATC
piroxicam; topical
2.7
18.6
155
780
M67.4
ICD-10 Finland
Ganglion
6.4
18.1
31
52
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
7.0
17.7
28
43
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
36.9
16.8
21
6
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
+∞
16.8
16
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.3
16.8
35
71
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
16.7
109
481
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
16.3
184
1055
M01AX17
ATC
nimesulide; oral
2.7
15.9
106
471
M01AB05
ATC
diclofenac; systemic, rectal
2.7
15.9
277
1929
M54.5
ICD-10 Finland
Low back pain
2.5
15.7
154
824
H02AB06
ATC
prednisolone; systemic
2.4
15.4
198
1193
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
15.3
150
801
A02BC03
ATC
lansoprazole; oral
2.5
15.3
129
643
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.9
15.0
47
132
M48.0
ICD-10 Finland
Spinal stenosis
3.5
14.7
56
180
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
5.9
14.5
27
49
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.3
14.4
62
215
M01AE02
ATC
naproxen; oral, rectal
2.4
14.3
230
1511
ACC51
NOMESCO Finland
Release of median nerve
4.3
14.2
38
95
L03
ICPC
Low back symptom/complaint
2.5
13.8
119
594
N06AX21
ATC
duloxetine; oral
3.3
13.4
55
185
M03BC01
ATC
orphenadrine (citrate); systemic
2.5
13.2
102
483
A02BC01
ATC
omeprazole; systemic
2.4
13.0
114
572
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.4
12.9
121
625
M01AB55
ATC
diclofenac, combinations; oral
4.2
12.9
36
93
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.0
12.6
38
104
M01AC06
ATC
meloxicam; systemic, rectal
2.2
12.5
152
874
UJF32
NOMESCO Finland
Coloscopy
2.4
12.3
114
585
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
12.1
151
875
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.4
12.0
47
153
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
9.7
11.7
23
25
M75.2
ICD-10 Finland
Bicipital tendinitis
10.6
11.7
22
22
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.1
11.4
185
1182
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
36.2
11.3
14
*
M54.2
ICD-10 Finland
Cervicalgia
3.4
11.1
41
129
M77.1
ICD-10 Finland
Lateral epicondylitis
3.7
11.0
37
109
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
10.9
75
334
N02BE01
ATC
paracetamol; systemic, rectal
3.8
10.9
347
2911
A02BC02
ATC
pantoprazole; systemic
2.2
10.8
272
2039
M13.9
ICD-10 Finland
Arthritis, unspecified
3.7
10.7
35
101
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.4
10.7
41
132
L17
ICPC
Foot/toe symptom/complaint
2.2
10.6
121
671
J01FA06
ATC
roxithromycin; oral
2.1
10.6
161
997
R52.9
ICD-10 Finland
Pain, unspecified
3.0
10.5
49
177
L13
ICPC
Hip symptom/complaint
2.4
10.5
83
393
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
113.1
10.5
11
*
NB1ZT
NOMESCO Finland
Crushing of soft tissue calcifications in shoulder wiht ultrasound quidance
+∞
10.5
10
*
M79.1
ICD-10 Finland
Myalgia
2.8
10.5
57
225
M02AA10
ATC
ketoprofen; topical
2.6
10.5
70
307
SPAT1263
SPAT
Sampling
2.1
10.4
160
993
WX400
NOMESCO Finland
Inhalation anesthesy
4.2
10.2
28
71
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.5
10.2
25
58
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.3
10.1
88
435
N02BF02
ATC
pregabalin; oral
3.7
10.0
33
96
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
10.0
105
562
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
10.0
113
623
M47.82
ICD-10 Finland
Other spondylosis, cervical region
5.4
9.9
20
39
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.6
9.8
34
102
N06AA09
ATC
amitriptyline; systemic
3.1
9.8
43
150
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.1
9.8
27
69
M54.6
ICD-10 Finland
Pain in thoracic spine
3.2
9.8
40
134
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
56.5
9.7
11
*
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.0
9.7
44
157
N02BF01
ATC
gabapentin; oral
3.1
9.5
42
147
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
9.5
112
626
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
9.5
41
142
M79.7
ICD-10 Finland
Fibromyalgia
12.8
9.4
16
13
A02BC05
ATC
esomeprazole; systemic
2.0
9.3
158
1006
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
9.3
30
86
R01AD09
ATC
mometasone; nasal
2.0
9.2
185
1249
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
9.1
163
1055
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.3
9.1
77
375
S18
ICPC
Laceration/cut
1.9
9.1
187
1270
J01AA02
ATC
doxycycline; systemic
2.3
9.0
303
2441
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.9
8.9
20
43
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
8.9
37
125
P01AB01
ATC
metronidazole; oral, rectal
1.9
8.9
166
1089
R01AD08
ATC
fluticasone; nasal
2.0
8.7
118
691
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
8.7
74
361
SPAT1260
SPAT
Consultation of another employee
2.3
8.6
71
341
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
8.6
100
553
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.3
8.6
22
53
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.8
8.6
27
76
J01FF01
ATC
clindamycin; systemic
2.1
8.5
107
608
M54.8
ICD-10 Finland
Other dorsalgia
4.5
8.5
21
49
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
8.5
72
350
J01DB01
ATC
cefalexin; oral
2.3
8.3
313
2585
J01DA01
ATC
[U] cefalexin
1.9
8.2
231
1717
SFA10
NOMESCO Finland
One-surface restoration
1.9
8.2
217
1581
SPAT1153
SPAT
Removal of sutures
2.0
8.2
120
720
XA402
NOMESCO Finland
ENMG
9.2
8.1
16
18
C10AX09
ATC
ezetimibe; oral
2.2
8.1
75
378
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
8.1
275
2171
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
8.1
167
1122
WX204
NOMESCO Finland
Axillary plexus blockaced
4.6
8.0
19
43
WX720
NOMESCO Finland
Own respiration
3.6
8.0
27
80
H02BX01
ATC
methylprednisolone, combinations; systemic
4.0
7.9
23
61
SPAT1216
SPAT
Assessment of functional ability
2.4
7.9
56
251
M70.7
ICD-10 Finland
Other bursitis of hip
8.7
7.9
16
19
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
7.9
115
688
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
7.9
113
672
WX200
NOMESCO Finland
Interscalenous plexus blockade
11.1
7.9
14
13
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.4
7.9
58
265
R06AE07
ATC
cetirizine; oral
1.9
7.8
166
1123
R42
ICD-10 Finland
Dizziness and giddiness
2.1
7.8
90
495
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
7.7
77
400
R03AC02
ATC
salbutamol; inhalant
1.8
7.7
209
1523
SPAT1254
SPAT
Administration of medicine
2.5
7.7
53
235
M01AX01
ATC
nabumetone; oral
4.4
7.6
19
45
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
7.5
46
192
SPAT1325
SPAT
Vaccination
1.9
7.5
118
722
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
7.5
140
906
G01AF01
ATC
metronidazole; vaginal
2.5
7.5
50
218
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
3.1
7.5
32
110
M76.6
ICD-10 Finland
Achilles tendinitis
3.9
7.5
22
59
M76.0
ICD-10 Finland
Gluteal tendinitis
7.9
7.5
16
21
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
7.4
253
1969
M75.5
ICD-10 Finland
Bursitis of shoulder
7.1
7.4
17
25
SFA00
NOMESCO Finland
Small restoration
2.3
7.4
61
293
M01AE11
ATC
tiaprofenic acid; oral, rectal
4.3
7.4
19
46
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.1
7.3
82
444
RF410, ,
NOMESCO Finland
11.2
7.3
13
12
SFA20
NOMESCO Finland
Two-surface restoration
1.8
7.3
230
1741
7261A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[TENDINITIS CALCIFICANS HUMEROSCAPULARIS]
+∞
7.3
7
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
7.3
212
1567
R01AD58
ATC
fluticasone, combinations; nasal
2.0
7.3
103
607
R03BA01
ATC
beclometasone; inhalant
2.3
7.2
56
262
Z01.2
ICD-10 Finland
Dental examination
1.8
7.2
173
1208
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
20.5
7.2
10
5
A02BA02
ATC
ranitidine; systemic
2.1
7.1
74
390
RF420, ,
NOMESCO Finland
10.3
7.1
13
13
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
7.1
148
989
M01AB08
ATC
etodolac; oral
3.0
7.0
32
114
L12
ICPC
Hand/finger symptom/complaint
2.2
7.0
67
341
J01CA04
ATC
amoxicillin; systemic
2.1
7.0
305
2549
L15
ICPC
Knee symptom/complaint
1.9
7.0
99
584
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.7
6.9
37
144
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.5
6.9
46
200
J01FA09
ATC
clarithromycin; systemic
1.9
6.9
120
757
R51.80
ICD-10 Finland
Headache
2.3
6.8
58
281
EB1VA, ,
NOMESCO Finland
2.1
6.8
78
425
SPAT1310
SPAT
Counselling related to known health issue
1.9
6.8
113
700
R06AX27
ATC
desloratadine; oral
1.9
6.8
111
684
RF210, ,
NOMESCO Finland
4.4
6.8
17
40
C10AA04
ATC
fluvastatin; oral
2.9
6.8
33
122
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
6.8
123
784
B01AC04
ATC
clopidogrel; oral
2.2
6.8
61
303
R02
ICPC
Shortness of breath/dyspnoea
2.3
6.7
52
242
R03DC03
ATC
montelukast; oral
2.1
6.7
68
354
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.8
6.6
122
781
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
4.3
6.6
17
41
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
7.1
6.6
15
22
XCK00
NOMESCO Finland
Perimetry
3.1
6.5
27
91
M54.1
ICD-10 Finland
Radiculopathy
4.1
6.5
18
46
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
6.5
94
556
R05DA01
ATC
ethylmorphine; oral
2.7
6.5
36
143
R03BA08
ATC
ciclesonide; inhalant
2.5
6.5
41
174
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.7
6.4
34
132
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
6.4
31
115
NF1AA
NOMESCO Finland
Hip X-ray examination
2.7
6.3
34
133
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
6.3
267
2164
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.8
6.3
19
52
NBL50
NOMESCO Finland
Tenolysis or tenosynovectomy of shoulder or upper arm
+∞
6.3
6
*
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
27.2
6.3
8
*
M01AH02
ATC
rofecoxib; oral
2.4
6.2
43
190
E0000UV, ,
ATC
1.7
6.2
154
1071
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.5
6.2
21
62
R05FB02
ATC
cough suppressants and expectorants; systemic
1.8
6.2
137
922
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
6.2
37
153
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.8
6.2
31
117
-1, ,
NOMESCO Finland
1.8
6.1
122
796
R74
ICPC
Upper respiratory infection acute
1.8
6.1
123
805
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
6.1
43
192
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
6.9
6.1
14
21
J02AC01
ATC
fluconazole; systemic
1.7
6.1
152
1059
C05AA08
ATC
fluocortolone; rectal, topical
2.2
6.1
57
288
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
6.1
104
649
R21
ICPC
Throat symptom/complaint
2.0
6.1
73
405
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.9
6.0
94
569

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
100
502
2.36
11.20
1.5
1.2
4.31
20.15
u/ml
2.29
52
192
135
795
2.09
10.04
3.0
2.7
333.20
340.68
umol/l
0.38
123
706
103
562
2.15
9.24
1.4
1.2
30.73
37.30
iu/ml
0.26
27
190
63
289
2.42
8.48
3.7
5.2
0.00
0.19
%
1.18
12
74
139
880
1.92
8.09
4.8
3.5
0.00
0.01
estimate
0.74
52
302
183
1273
1.86
7.90
4.2
3.3
0.00
0.03
estimate
1.34
44
269
152
1004
1.87
7.67
3.2
2.4
53.10
72.19
u/l
2.20
142
938
306
2538
2.15
7.49
5.0
4.2
14.84
14.69
pmol/l
0.44
287
2340
303
2506
2.11
7.44
7.7
8.6
72.38
80.65
u/l
4.56
293
2389
215
1599
1.81
7.23
7.8
7.5
1.22
1.21
mmol/l
0.32
184
1398
355
3166
3.51
7.07
17.4
14.3
20.07
24.71
mg/l
1.92
304
2531
223
1694
1.79
6.82
5.9
5.9
2.04
1.89
e9/l
1.17
207
1492
219
1670
1.75
6.46
5.7
5.9
0.05
0.04
e9/l
1.81
201
1429
219
1671
1.75
6.44
4.5
3.4
0.00
0.00
estimate
-0.00
53
321
218
1667
1.74
6.30
5.8
5.9
0.60
0.58
e9/l
0.72
199
1426
217
1660
1.73
6.24
4.5
3.4
0.00
0.00
estimate
-0.00
53
313
348
3117
2.74
5.95
8.1
6.0
40.55
39.01
mmol/mol
2.11
329
2927
221
1714
1.71
5.91
6.0
6.4
0.22
0.18
e9/l
2.04
205
1500
219
1698
1.70
5.83
4.5
3.4
0.06
0.01
estimate
0.35
51
302
179
1317
1.69
5.79
3.7
3.1
6.23
6.17
ph
0.29
102
771
264
2160
1.76
5.72
4.9
4.1
—
1.91
—
0
5
233
1843
1.70
5.70
5.6
5.0
6.67
6.68
mmol/l
0.02
222
1753
339
3019
2.35
5.54
6.2
5.1
1.93
1.92
mu/l
0.08
318
2787
54
278
2.10
5.47
3.8
4.9
0.00
0.15
%
—
10
75
131
897
1.71
5.46
3.3
3.2
749.29
1124.89
ng/l
0.97
118
769
74
429
1.90
5.37
1.2
1.2
—
—
—
0
0
351
3185
2.73
5.31
5.6
5.0
6.18
5.92
mmol/l
1.97
328
2953
135
939
1.69
5.28
2.5
2.1
169.58
268.09
u/l
0.59
125
888
68
386
1.93
5.25
2.0
2.5
218.35
146.67
ug/g
0.30
51
321
56
298
2.03
5.19
3.7
4.8
0.46
1.25
%
1.58
12
95
54
285
2.05
5.11
3.3
4.8
0.38
0.78
%
1.13
13
88
190
1452
1.63
5.08
4.7
5.0
36.41
35.94
g/l
0.65
178
1383
362
3350
3.73
5.06
16.8
12.9
—
—
—
0
0
107
706
1.72
5.05
4.5
3.5
1.02
1.02
kg/l
0.74
63
478
220
1746
1.63
5.03
5.4
7.4
10.19
11.63
umol/l
1.93
212
1681
358
3299
3.12
4.90
6.0
5.1
4.60
4.75
mmol/l
2.06
336
3098
153
1116
1.63
4.89
4.2
3.5
—
0.83
—
0
6
357
3289
2.99
4.81
5.8
5.0
1.44
1.50
mmol/l
2.15
337
3066
365
3449
3.72
4.76
13.4
11.7
27.15
25.98
u/l
0.57
358
3350
70
414
1.85
4.75
1.4
1.3
886.67
436.24
titre
0.48
12
85
185
1423
1.60
4.69
5.9
6.7
1.22
1.21
mmol/l
0.12
166
1325
196
1535
1.58
4.56
5.9
6.0
56.47
57.50
%
0.67
187
1469
360
3345
3.19
4.50
6.6
5.7
2.65
2.78
mmol/l
2.11
339
3127
32
145
2.32
4.42
1.2
1.2
—
—
—
0
0
187
1456
1.57
4.41
8.0
11.2
1.15
1.20
inr
0.78
155
1186
49
265
1.98
4.34
2.7
2.1
0.00
0.06
estimate
0.49
14
48
193
1524
1.55
4.21
5.8
6.1
0.79
0.71
%
1.32
181
1422
38
191
2.10
4.10
3.5
3.5
—
—
—
0
0
155
1171
1.55
4.09
5.1
3.4
81.54
33.30
ng/l
0.41
111
817
66
403
1.77
4.02
3.1
3.8
4.11
6.06
e9/l
0.77
57
354
344
3155
2.16
4.01
5.0
4.2
1.42
1.28
mmol/l
2.03
323
2929
196
1566
1.53
3.97
5.9
6.1
29.75
27.64
%
2.14
185
1480
106
741
1.60
3.88
4.8
5.0
—
—
—
0
0
34
168
2.13
3.84
4.0
8.1
—
—
—
0
0
94
645
1.61
3.70
1.8
1.7
85897866.44
42115122.43
pmol/l
0.20
78
558
58
350
1.78
3.67
2.1
1.5
—
—
—
0
0
101
713
1.57
3.51
1.3
1.2
3.69
1.88
u/ml
0.30
39
186
96
670
1.58
3.50
1.9
1.7
0.90
1.37
mg/l
1.49
79
521
57
350
1.74
3.40
4.9
9.6
7.41
7.41
ph
0.18
35
199
189
1531
1.48
3.39
5.9
6.0
2.93
2.79
%
0.44
177
1434
29
142
2.13
3.37
3.0
2.2
0.00
6.12
estimate
0.49
13
41
189
1536
1.47
3.31
6.0
6.1
8.76
8.95
%
0.49
177
1440
182
1469
1.47
3.30
2.7
2.4
77.65
77.78
nmol/l
0.02
166
1337
56
346
1.73
3.27
5.0
9.6
1.36
0.83
mmol/l
0.46
47
286
179
1449
1.45
3.15
2.8
2.7
—
—
estimate
—
0
0
222
1876
1.45
3.08
7.6
10.6
4.35
4.02
e9/l
1.23
204
1636
20
89
2.32
2.92
1.2
1.1
—
—
—
0
0
33
180
1.91
2.89
2.8
2.4
32.54
6.52
au/ml
—
7
11
266
2350
1.46
2.75
4.4
3.8
—
12627.25
—
0
8
30
162
1.93
2.71
1.6
1.3
76.22
37.05
au/ml
—
5
14
15
61
2.52
2.65
2.4
1.8
102.25
1748.96
u/l
—
6
23
123
956
1.43
2.58
3.8
2.8
0.04
0.00
estimate
0.43
49
253
10
31
3.29
2.53
1.4
1.3
—
—
—
0
0
15
63
2.44
2.49
1.3
1.2
441.20
454.02
mg/l
0.07
15
58
232
2030
1.38
2.32
5.1
4.0
2768.83
1526.78
e6/l
—
6
27
68
483
1.50
2.26
1.9
1.7
1179.34
1176.55
nmol/l
0.01
56
364
9
29
3.15
2.24
1.0
1.0
—
—
—
0
0
89
672
1.43
2.16
3.3
2.4
7.36
6.79
e6/l
0.12
84
607
173
1458
1.35
2.14
2.0
1.9
1.40
1.33
mmol/l
0.41
151
1229
43
279
1.61
2.12
4.3
4.6
7.36
7.35
ph
0.29
27
207
133
1079
1.36
2.10
5.2
5.8
—
—
—
0
0
174
1473
1.34
2.07
13.8
10.9
0.00
0.00
e9/l
0.02
157
1203
19
97
2.01
2.04
1.3
1.5
369.08
300.58
ug/g
0.62
13
57
54
374
1.52
2.02
1.3
1.4
—
—
—
0
0
253
2271
1.35
2.00
3.5
3.2
51.01
52.44
u/l
0.08
236
2154
17
85
2.05
1.93
1.6
1.2
0.22
0.25
g/l
0.63
17
79
35
222
1.64
1.90
1.3
1.3
—
—
—
0
0
133
1094
1.34
1.89
4.0
3.3
68.49
44.73
mg/l
0.50
96
690
138
1144
1.33
1.85
3.8
3.2
7.73
7.72
mmol/l
0.01
125
969
22
123
1.84
1.84
1.7
1.4
6.72
4.74
iu/ml
—
5
28
17
89
1.95
1.73
1.6
1.2
1.23
1.23
g/l
0.00
17
84
5
13
3.88
1.72
1.0
1.6
128.60
198.77
mmol/24h
—
5
13
134
1117
1.31
1.71
4.5
4.0
18.41
7.70
mg/mmol
0.89
98
680
22
127
1.78
1.68
8.0
3.7
36.90
36.94
°c
0.14
22
127
38
255
1.55
1.66
3.4
2.2
0.16
0.52
e6/l
1.20
38
245
39
266
1.52
1.59
2.4
3.0
65.41
69.56
e9/l
0.37
31
195
11
50
2.24
1.58
1.1
1.3
—
—
—
0
0
0
42
0.00
1.53
0.0
1.2
—
—
—
0
0
9
38
2.40
1.46
3.0
3.1
3.41
4.12
e9/l
—
9
38
5
16
3.15
1.44
5.4
1.8
9.52
7.36
mmol/l
—
5
16
134
1139
1.28
1.43
3.1
4.0
2.35
2.36
mmol/l
0.53
124
1050
49
364
1.40
1.32
1.6
1.6
—
—
—
0
0
8
34
2.38
1.30
1.1
1.2
—
—
—
0
0
5
18
2.80
1.29
1.2
1.3
—
—
—
0
0
172
1523
1.24
1.26
3.4
2.8
137.33
132.79
ug/l
0.09
165
1425
18
108
1.70
1.24
3.2
4.2
220.71
258.44
mg/l
—
7
50
5
19
2.65
1.22
1.2
1.7
71.00
118.32
ng/l
—
5
19
34
240
1.46
1.21
1.2
1.1
—
—
—
0
0
6
26
2.33
1.19
1.8
4.2
2129.50
1285.23
mg
—
6
26
8
38
2.13
1.19
1.8
1.9
1.39
1.61
mmol/l
—
8
38
33
233
1.46
1.18
2.5
4.2
67.09
67.22
g/l
0.03
28
217
0
34
0.00
1.16
0.0
1.8
—
—
—
0
0
29
200
1.49
1.16
2.4
3.5
—
—
—
0
0
55
430
1.33
1.10
2.5
2.1
—
—
—
0
0
8
41
1.97
1.09
1.1
1.3
19.11
27.88
ng/l
—
8
41
106
903
1.24
1.08
2.9
2.8
—
—
—
0
0
7
32
2.21
1.08
3.6
2.7
—
—
—
0
0
20
129
1.58
1.08
1.2
1.2
—
—
—
0
0
7
33
2.14
1.06
1.1
1.2
—
—
—
0
0
21
138
1.55
1.05
3.3
4.0
—
—
—
0
0
27
188
1.47
1.05
6.3
10.1
94.93
93.05
%
1.72
27
188
70
570
1.28
1.04
3.4
2.6
531.31
542.09
mosm/kgh2o
0.17
64
495
5
22
2.29
1.03
1.8
1.9
13.84
16.78
mu/l
—
5
22
291
2757
1.25
1.02
19.3
17.8
13.62
13.62
%
0.02
291
2719
159
1426
1.20
0.97
2.1
2.0
106.51
95.56
pmol/l
2.09
96
752
39
296
1.35
0.96
1.5
1.4
—
—
—
0
0
72
597
1.26
0.93
3.7
3.6
303.16
410.49
ng/l
0.21
58
467
10
55
1.84
0.93
1.7
3.6
—
—
—
0
0
22
151
1.49
0.93
2.5
2.3
—
—
—
0
0
91
776
1.23
0.92
2.8
2.0
3.04
3.01
mg/l
0.06
86
665
117
1024
1.21
0.92
2.2
2.3
—
—
—
0
0
150
1346
1.19
0.89
1.8
2.1
—
—
—
0
0
114
998
1.20
0.89
3.8
2.9
57.03
128.53
e6/l
0.44
92
757
6
30
2.02
0.87
1.2
1.2
101.33
104.40
pmol/l
—
6
30
42
328
1.32
0.87
1.4
1.5
—
—
—
0
0
24
330
0.71
0.86
1.8
1.4
—
—
—
0
0
8
44
1.84
0.86
2.6
2.4
—
—
—
0
0
6
31
1.95
0.84
1.0
1.1
—
—
—
0
0
129
1148
1.19
0.84
3.2
3.2
26.69
33.71
u/l
2.43
123
1097
15
97
1.57
0.82
1.3
1.1
—
—
—
0
0
113
996
1.19
0.81
3.5
4.2
7.39
7.40
ph
0.90
83
712
12
74
1.64
0.79
1.6
1.7
—
—
—
0
0
104
913
1.19
0.78
1.7
1.6
18.59
20.19
nmol/l
0.58
92
769
98
857
1.19
0.77
3.0
2.8
0.51
0.64
e6/l
0.24
78
620
0
28
0.00
0.76
0.0
16.4
—
841.11
—
0
28
37
465
0.77
0.75
1.4
1.3
—
—
—
0
0
5
24
2.10
0.75
1.4
1.4
—
—
—
0
0
9
56
1.62
0.73
1.3
1.1
—
—
—
0
0
9
59
1.54
0.69
1.6
1.4
—
—
—
0
0
5
27
1.86
0.68
1.0
1.3
1.46
0.91
promille
—
5
21
5
27
1.86
0.68
2.6
1.6
10.66
10.88
%
—
5
27
7
44
1.60
0.65
1.0
1.6
—
—
—
0
0
23
173
1.35
0.63
3.9
2.2
0.68
0.64
%
0.29
23
173
8
50
1.61
0.61
1.3
1.6
—
—
—
0
0
5
30
1.68
0.61
1.2
1.2
—
—
—
0
0
5
30
1.68
0.61
1.4
4.3
—
—
—
0
0
8
51
1.58
0.61
4.2
4.2
6.59
9.74
pmol/l
—
8
51
12
80
1.52
0.60
2.8
4.2
—
—
—
0
0
108
973
1.15
0.59
5.2
5.3
14.77
2.65
ug/l
0.48
88
874
0
23
0.00
0.58
0.0
1.9
—
36.07
—
0
15
14
195
0.71
0.57
1.9
2.6
24.97
47.67
u/ml
0.71
14
189
6
36
1.68
0.57
1.2
1.3
—
—
nmol/l
—
0
0
6
36
1.68
0.57
3.7
3.9
3.02
151.24
nmol/l
—
6
36
14
99
1.43
0.55
1.3
1.2
—
—
—
0
0
9
61
1.49
0.54
3.8
2.6
54.00
58.05
%
—
9
61
126
1158
1.13
0.52
4.5
3.4
66.24
74.58
e6/l
0.13
98
803
73
647
1.16
0.50
1.5
1.6
2.55
2.40
g/l
0.22
51
425
12
84
1.44
0.50
1.8
3.0
1.00
3.23
index
—
5
47
7
106
0.65
0.49
1.3
1.3
—
—
—
0
0
13
93
1.41
0.49
2.2
5.0
1.13
2.67
ratio
—
8
52
153
1430
1.12
0.47
3.7
3.2
—
—
—
0
0
7
48
1.47
0.47
2.3
2.8
3.89
4.00
mmol/l
—
7
48
7
48
1.47
0.47
2.3
2.8
103.29
105.06
mmol/l
—
7
48
18
138
1.32
0.46
1.3
1.2
0.81
0.91
g/l
1.01
18
138
21
264
0.78
0.46
3.9
3.1
9.61
10.98
g/l
1.00
21
246
14
103
1.37
0.46
11.1
7.6
—
—
—
0
0
16
122
1.33
0.43
2.4
1.8
—
—
—
0
0
12
87
1.39
0.42
1.5
1.3
—
—
—
0
0
5
32
1.57
0.42
4.0
2.3
—
—
—
0
0
5
32
1.57
0.42
1.4
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
14
107
1.32
0.37
5.7
1.9
505.50
656.92
ug/l
0.11
14
102
9
69
1.31
0.37
2.6
5.8
—
—
—
0
0
5
37
1.36
0.37
2.0
2.0
2.02
1.42
mmol/l
—
5
37
32
371
0.85
0.35
1.8
2.4
15.48
7.82
umol/l
0.37
24
331
6
45
1.34
0.34
3.7
2.8
—
—
—
0
0
6
46
1.31
0.33
2.5
2.8
1.28
1.19
mmol/l
—
6
46
38
333
1.16
0.32
4.8
2.8
7.38
7.39
ph
0.08
24
194
17
137
1.25
0.32
1.4
1.2
1.44
1.61
g/l
2.15
17
137
17
208
0.81
0.32
1.8
1.8
—
—
—
0
0
53
481
1.12
0.28
2.2
1.8
—
—
—
0
0
91
851
1.09
0.28
4.6
4.1
—
—
—
0
0
8
67
1.20
0.26
1.7
2.1
5.93
4.95
mmol/24h
—
8
61
26
226
1.16
0.25
1.1
1.2
22.43
137.37
u/ml
—
8
95
33
369
0.88
0.24
1.4
1.4
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
46
421
1.11
0.22
1.7
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
3.1
—
8.07
—
0
11
0
10
0.00
0.21
0.0
1.8
—
0.58
—
0
10
0
12
0.00
0.21
0.0
1.7
—
4722.83
—
0
6
19
219
0.86
0.21
1.7
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
102
971
1.07
0.20
5.1
6.7
—
—
—
0
0
6
48
1.25
0.20
1.5
2.3
31.17
32.65
pg
—
6
48
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.8
1.6
—
—
—
0
0
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
7
63
1.11
0.17
2.4
1.6
56.06
62.65
%
—
7
63
30
273
1.11
0.16
14.7
7.8
10.65
9.69
mmol/l
0.28
30
261
11
92
1.20
0.16
3.1
1.5
—
—
—
0
0
11
92
1.20
0.16
2.6
1.5
—
—
—
0
0
11
92
1.20
0.16
2.6
1.5
—
—
—
0
0
11
92
1.20
0.16
2.7
1.5
—
—
—
0
0
26
235
1.11
0.16
2.3
2.3
5.94
6.07
ph
0.32
17
160
36
332
1.09
0.16
2.2
1.6
—
—
—
0
0
16
141
1.14
0.14
1.0
1.1
—
—
—
0
0
41
384
1.08
0.13
2.3
5.4
5.92
44.19
ug/l
1.10
35
321
11
94
1.18
0.13
2.9
2.0
2.83
5.02
iu/l
—
5
45
10
85
1.18
0.12
2.8
1.5
—
—
—
0
0
47
495
0.94
0.11
2.8
2.7
7.77
2.50
e6/l
0.80
26
243
56
583
0.95
0.09
2.9
3.1
0.70
0.75
ug/l
0.27
33
385
5
64
0.78
0.08
1.8
2.0
—
—
—
0
0
7
66
1.06
0.08
1.3
1.1
—
—
—
0
0
7
67
1.05
0.08
1.3
1.1
—
—
—
0
0
6
70
0.85
0.07
1.2
1.2
12.61
49.55
u/l
—
6
64
9
102
0.88
0.06
2.6
2.5
1.55
1.48
mg/l
—
9
93
23
243
0.94
0.06
4.9
3.1
—
—
—
0
0
28
268
1.05
0.05
5.7
8.2
—
—
—
0
0
27
277
0.97
0.01
2.0
1.8
3.30
3.56
mmol/l
0.71
22
208
19
185
1.03
0.00
1.2
1.1
—
—
—
0
0
90
905
0.99
0.00
1.4
1.4
—
—
—
0
0
12
124
0.97
0.00
2.8
2.6
—
—
—
0
0
42
425
0.99
0.00
2.1
1.6
—
—
—
0
0
23
234
0.98
0.00
1.6
1.5
—
—
—
0
0
8
86
0.93
0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
2.44
—
0
9
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
68
0.88
-0.00
3.7
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
6.04
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
31.89
—
0
9
6
63
0.95
-0.00
1.7
1.2
211.83
277.32
u/ml
—
6
34
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
2.6
3.1
25.57
35.39
umol/l
—
7
70
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
572.80
—
0
5
5
49
1.02
-0.00
2.4
3.0
0.86
0.77
nmol/l
—
5
41
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5

Mortality – FinRegistry

Association

Association between endpoint M13_CALCTENDINITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.851 [0.67, 1.07] 0.175
Birth year 0.995 [0.99, 1.0] 0.238

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 1127 females with M13_CALCTENDINITIS died.

Males

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.862 [0.68, 1.09] 0.209
Birth year 0.988 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 721 males with M13_CALCTENDINITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_CALCTENDINITIS.

N-year risk Females Males
1 0.077% 0.162%
5 0.494% 0.958%
10 1.316% 2.609%
15 2.429% 4.989%
20 4.252% 8.412%

Relationships between endpoints

Index endpoint: M13_CALCTENDINITIS – Calcific tendinitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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