Benign neoplasm: Respiratory system, unspecified

CD2_BENIGN_RESPIRATORY_NOS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D14.4& Hospital discharge: ICD-8 — 21299 Cause of death: ICD-10 — D14.4& Cause of death: ICD-8 — 21299 2 out of 7 registries used, show all original rules.	95
4. Check minimum number of events None	95
5. Include endpoints None	95
6. Filter based on genotype QC (FinnGen only)	76

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D14
Name in latin: Neoplasma benignum organi respiratorii non specificati

NAME	CD2_BENIGN_RESPIRATORY_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D144
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	21299
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D144
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	21299
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Respiratory system, unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	588	308	276
Only index persons	477	253	224
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	53.81	51.97	55.67
Only index persons	51.51	50.21	52.97

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	76	38	38
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	56.31	53.30	59.32

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
82: Matched controls
820

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D14.4

ICD-10 Finland

Benign neoplasm: Respiratory system, unspecified

+∞

93.5

21299

ICD-8 Finland

Benign neoplasm of respiratory system, Unspecified site

+∞

11.7

B97.7

ICD-10 Finland

Papillomavirus as the cause of diseases classified to other chapters

112.5

9.6

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

5.7

9.5

DHB10

NOMESCO Finland

Excision of lesion of internal nose

+∞

8.5

DQB10

NOMESCO Finland

Endoscopic excision of lesion of larynx

87.7

7.5

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3021589) Normoblasts [#/volume] in Blood

315

2.50

3.93

11.0

13.7

0.00

e9/l

0.50

250

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

350

2.33

3.31

9.0

6.5

1.20

1.21

mmol/l

0.87

293

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

4.68

3.10

1.7

1.6

—

(3001604) Monocytes [#/volume] in Blood

370

2.22

2.95

5.4

6.0

0.58

0.59

e9/l

0.10

314

(3013115) Eosinophils [#/volume] in Blood

382

2.21

2.88

6.0

6.1

0.19

0.20

e9/l

0.07

337

(3006315) Basophils [#/volume] in Blood

373

2.19

2.85

5.4

6.0

0.04

e9/l

0.11

315

(3019198) Lymphocytes [#/volume] in Blood

378

2.14

2.70

4.8

6.0

1.88

1.91

e9/l

0.06

337

(40758558) Short blood count panel - Blood

215

2.10

2.64

4.8

5.3

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

404

2.10

2.51

8.5

10.6

3.99

4.37

e9/l

0.60

352

(3021788) Differential panel - Synovial fluid

5.30

2.45

1.0

1.2

—

(3006504) Eosinophils/Leukocytes in Blood

340

1.99

2.37

5.5

5.9

2.48

2.86

0.56

315

(42870588) Differential panel, method unspecified - Blood

231

2.00

2.36

6.9

5.7

—

(40768804) Tissue Pathology biopsy report

278

1.95

2.27

2.9

2.1

—

(3023368) Bacteria identified in Blood by Culture

209

1.97

2.22

6.1

4.4

—

(3035715) Granulocytes [#/volume] in Blood

4.23

2.08

2.2

6.47

5.11

e9/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.31

2.08

1.9

1.7

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

2.43

1.96

1.4

—

(3042936) Bacteria identified in Isolate by Culture

103

2.10

1.92

1.8

2.2

—

(3035933) Granulocytes/Leukocytes in Blood

3.72

1.87

2.3

2.2

62.17

59.06

—

(3012544) pH of Venous blood

2.18

1.85

4.2

3.6

7.39

—

(3044941) Cell count panel - Synovial fluid

4.36

1.85

1.0

1.1

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

536

2.03

1.81

8.1

8.2

82.53

79.20

u/l

0.26

500

(3013512) EKG study

252

1.76

1.69

2.7

4.2

—

(3018418) pH of Serum or Plasma

217

1.78

1.66

5.2

4.0

7.39

7.40

0.21

156

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

2.85

1.62

1.1

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.15

1.61

2.2

1.4

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

698

2.69

1.53

25.5

19.1

3.98

3.99

mmol/l

0.15

689

(3019550) Sodium [Moles/volume] in Serum or Plasma

696

2.74

1.52

25.1

19.1

139.47

139.67

mmol/l

0.28

687

(3010421) pH of Blood

2.64

1.49

1.4

3.1

7.41

7.42

—

(3029937) Albumin [Presence] in Urine by Test strip

215

1.71

1.46

3.3

4.3

0.00

estimate

-0.00

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.28

1.40

5.7

3.0

24.48

24.31

mmol/l

—

(1616796) Gas panel - Central venous blood

3.06

1.38

4.8

2.6

—

(3005719) IgG [Mass/volume] in Serum or Plasma

2.10

1.36

1.4

1.9

11.38

10.63

g/l

0.23

(3002582) Erythrocytes [#/volume] in Urine

247

1.64

1.33

2.9

3.3

12.20

316.23

e6/l

0.59

184

(3019060) Gas panel - Arterial blood

2.17

1.31

1.6

3.9

—

(3037756) Immunofixation for Serum or Plasma

2.89

1.30

1.0

1.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

474

1.66

1.28

4.0

5.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.85

1.25

1.6

1.7

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

709

2.41

1.24

25.8

21.9

89.31

76.98

umol/l

0.46

704

(3027315) Oxygen [Partial pressure] in Blood

2.73

1.23

1.6

3.5

7.76

8.39

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

2.73

1.23

1.6

3.5

4.56

4.94

kpa

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

540

1.72

1.23

4.5

4.3

13.07

11.66

mm/h

0.20

497

(3009261) Glucose [Presence] in Urine by Test strip

395

1.60

1.23

3.4

4.4

0.00

estimate

-0.00

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.59

1.17

1.0

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

388

1.57

1.17

3.3

4.4

0.00

estimate

-0.00

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.11

1.15

23.3

7.3

25.01

24.06

mmol/l

—

(3025941) Bacteria identified in Stool by Culture

2.11

1.15

2.0

1.5

—

(3000991) Gas panel - Venous blood

1.93

1.11

19.3

6.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.98

1.04

21.0

6.8

23.66

24.56

mmol/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

169

1.59

1.03

1.8

1.7

2.02

1.26

mg/l

0.23

136

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

126

1.66

1.03

1.4

0.92

10.85

u/ml

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.94

1.02

1.3

1.7

1.09

1.15

g/l

—

(3035350) Ketones [Presence] in Urine by Test strip

397

1.50

0.99

3.4

4.4

0.00

estimate

-0.00

(40761511) CBC panel - Blood by Automated count

694

1.94

0.98

19.6

15.5

—

(3037121) Protein [Mass/volume] in Urine

0.00

0.97

0.0

3.0

—

157.92

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.97

0.96

2.0

1.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

121

1.62

0.93

1.7

2.0

—

(3019150) Specific gravity of Urine by Refractometry

166

1.54

0.89

3.3

3.9

1.02

kg/l

0.32

106

(3015736) pH of Urine

316

1.45

0.85

2.8

4.0

6.15

6.19

0.08

175

(3010813) Leukocytes [#/volume] in Blood

723

2.06

0.84

32.6

25.8

6.92

6.80

e9/l

0.17

710

(3026361) Erythrocytes [#/volume] in Blood

723

2.06

0.84

32.7

25.6

4.50

e12/l

0.04

710

(3007461) Platelets [#/volume] in Blood

723

2.06

0.84

32.8

25.6

235.17

248.67

e9/l

1.25

715

(3026008) Bacteria identified in Urine by Culture

213

1.48

0.84

3.4

3.5

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.94

0.83

1.8

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.88

0.81

2.2

1.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.70

0.80

8.3

6.8

—

(3045414) Leukocytes [Presence] in Urine

1.74

0.80

1.8

1.9

—

0.00

estimate

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.75

0.78

1.8

1.6

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.25

0.77

1.4

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.25

0.77

1.4

1.1

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

654

1.64

0.74

20.5

17.1

81.81

80.99

ml/min/173m2

0.12

604

(3028626) Oxygen [Partial pressure] in Capillary blood

2.06

0.74

4.4

2.0

8.02

7.87

kpa

—

(3018095) Leukocytes [#/volume] in Urine

285

1.40

0.72

3.9

4.2

37.00

76.70

e6/l

0.51

191

(3007164) IgA [Mass/volume] in Serum or Plasma

156

1.47

0.70

1.5

1.75

2.87

g/l

1.95

(40768443) Skin Pathology biopsy report

1.91

0.69

1.0

1.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

669

1.63

0.68

22.6

17.3

27.90

23.81

mg/l

0.52

566

(3008898) HLA-B27 [Presence]

1.84

0.67

1.0

1.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.61

0.67

4.6

4.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.64

0.67

2.3

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.55

0.62

1.6

1.8

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.71

0.62

2.8

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

215

1.38

0.62

3.1

3.0

0.23

0.37

e6/l

0.45

152

(46235355) HIV 1 and 2 tests - Meaningful Use set

124

1.47

0.62

2.9

1.9

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.61

0.0

1.5

—

(40768793) Breast Pathology biopsy report

0.00

0.61

0.0

1.4

—

(3027008) Opiates [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3016879) Cocaine [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.61

0.0

1.5

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.61

0.0

1.4

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.60

0.0

1.4

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.60

0.0

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.77

0.59

1.5

1.1

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

1.77

0.59

1.5

0.90

8.84

ug/l

—

(4035726) Immunohistochemistry procedure

1.59

0.55

1.3

1.4

—

(40768797) Stomach Pathology biopsy report

102

1.45

0.51

1.2

—

(3002256) Pathology report gross observation

1.44

0.47

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.50

0.44

1.3

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.49

0.44

2.2

2.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.45

0.44

1.3

2.2

0.19

0.22

g/l

—

(40761536) Microorganisms panel - Urine sediment

1.42

0.43

4.1

4.4

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

189

1.30

0.42

1.5

1.3

0.97

1.73

u/ml

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.41

0.0

1.3

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.0

—

2.20

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

3.6

—

4.04

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

3.6

—

106.19

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

3.6

—

1.19

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

295

1.26

0.41

3.4

4.4

0.00

estimate

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.41

0.0

1.4

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

2.3

—

6.52

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

162

1.31

0.40

4.0

2.9

2.47

2.45

mmol/l

0.33

146

(3020630) Protein [Mass/volume] in Serum or Plasma

1.41

0.40

1.3

1.8

70.61

67.39

g/l

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.39

0.0

4.7

—

99.16

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

527

1.27

0.39

4.0

4.6

14.91

14.87

pmol/l

0.04

473

(1761868) Lipid panel - Serum or Plasma

282

0.79

0.38

3.0

3.5

—

(3020891) Body temperature

1.50

0.37

1.5

4.0

37.00

36.89

°c

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.43

0.36

1.0

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

138

1.29

0.34

1.6

1.3

33.14

39.88

iu/ml

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

340

1.22

0.34

3.2

2.4

—

estimate

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

111

1.32

0.32

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

292

1.22

0.32

4.8

4.5

17.11

41.39

ng/l

1.57

215

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.34

0.30

1.8

1.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

171

0.78

0.30

2.9

1.9

—

(3022145) Colonoscopy Study observation

1.31

0.28

1.6

1.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.28

0.27

2.6

1.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.26

0.26

1.6

1.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

117

1.24

0.22

2.1

3.1

0.20

3.06

e6/l

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

2.2

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

1.1

—

110.91

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.2

—

4.51

—

(4268621) Lupus anticoagulant assay

0.00

0.21

0.0

1.9

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

63.32

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

2.3

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.1

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.9

—

72.65

—

(3009343) pH of Capillary blood

1.24

0.20

4.3

2.5

7.38

7.43

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

224

1.17

0.20

3.2

4.0

0.00

estimate

-0.00

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.19

0.20

4.3

2.5

4.95

4.97

kpa

—

(3000494) Fungus identified in Specimen by Culture

1.24

0.18

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

110

1.22

0.18

1.9

1.6

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

679

1.21

0.18

6.1

2.65

2.62

mmol/l

0.07

623

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

315

0.88

0.17

2.9

2.1

88.47

96.89

pmol/l

0.53

165

(40760892) CBC W Ordered Manual Differential panel - Blood

182

1.13

0.12

4.0

5.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

213

1.11

0.11

5.2

4.7

20.09

22.24

0.29

104

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.17

0.10

1.2

1.1

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.04

0.09

4.0

2.7

0.36

0.65

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.82

0.08

2.4

1.5

—

(36660697) Celiac disease serology panel - Serum

0.79

0.08

1.2

1.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.08

0.08

2.4

1.9

—

(3000492) Spirometry study

1.11

0.08

1.5

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

253

0.93

0.06

3.3

3.9

2.87

7.49

mg/mmol

1.02

154

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

132

1.07

0.03

4.9

3.4

434.88

317.69

ng/l

—

102

(3003694) ABO and Rh group [Type] in Blood

203

1.05

0.01

1.5

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

234

1.04

0.00

2.9

2.0

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

266

0.97

0.00

6.7

5.2

3.60

1.80

ug/l

1.25

238

(3012516) Albumin [Mass/volume] in Urine

242

0.99

0.00

2.9

3.3

23.13

47.62

mg/l

0.87

160

(3003458) Phosphate [Moles/volume] in Serum or Plasma

107

1.03

0.00

9.5

3.8

1.23

1.02

mmol/l

0.82

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

637

1.02

0.00

5.2

5.6

1.84

2.00

mu/l

0.40

579

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

653

0.98

0.00

6.5

6.8

38.83

40.02

mmol/mol

0.60

615

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

415

1.02

0.00

4.0

3.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

125

1.05

0.00

2.2

2.8

0.82

0.96

e6/l

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

90.75

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.00

0.00

4.0

2.8

0.78

1.43

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

1.4

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

72.40

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

12.0

—

9.23

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3013727) Leukocytes other/Leukocytes in Blood

0.00

-0.00

0.0

4.4

—

51.00

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

6.2

—

201.20

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.4

—

0.20

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.00

-0.00

1.7

1.4

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.2

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

2.0

—

(4195642) Thrombophilia screening test

0.00

-0.00

0.0

1.1

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.5

—

6.78

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

11.86

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

1.4

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

215.29

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

7.1

—

136.19

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

2.4

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.2

—

20.02

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

43.24

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

10.13

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

1.4

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

12.0

—

16.52

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.91

-0.00

1.3

1.4

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RESPIRATORY_NOS and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RESPIRATORY_NOS	1.947 [1.32, 2.87]	< 0.001
Birth year	0.987 [0.98, 1.0]	0.006

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 183 males with CD2_BENIGN_RESPIRATORY_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RESPIRATORY_NOS.

N-year risk	Females	Males
1	No data	0.295%
5	No data	2.14%
10	No data	5.616%
15	No data	10.662%
20	No data	17.775%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RESPIRATORY_NOS – Benign neoplasm: Respiratory system, unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Respiratory system, unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints