obsolete_meningioma: ['A tumor of meningothelial cells that are manifested in the central nervous system and arise from the arachnoid "cap" cells of the arachnoid villi in the meninges.']
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
636 |
4. Check minimum number of eventsNone |
636 |
5. Include endpointsNone |
636 |
6. Filter based on genotype QC (FinnGen only) |
573 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D32
- Name in latin
- Neoplasma benignum meningum non specificatarum
Similar endpoints
↥List of similar endpoints to
Beningn neoplasm: Meninges, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of meninges
- Benign neoplasms
- Neoplasms
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4723 | 3470 | 1207 |
| Only index persons | 3764 | 2825 | 939 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.03 |
| Only index persons | 0.09 | 0.10 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 67.64 | 68.49 | 64.97 |
| Only index persons | 65.31 | 65.95 | 63.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 573 | 414 | 159 |
| Unadjusted period prevalence (%) | 0.13 | 0.15 | 0.07 |
| Median age at first event (years) | 63.66 | 62.26 | 67.31 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 593
- Matched controls
- 5930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
4503599627370496.0
307.7
589
*
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
125.0
307.7
170
19
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
111.4
307.7
190
25
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
152.2
307.7
238
26
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
178.8
307.7
301
34
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
13.4
202.6
244
295
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
59.8
153.9
87
17
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
38.3
108.6
68
20
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
9.4
86.8
115
148
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
132.3
85.6
90
8
N03AX14
ATC
levetiracetam; systemic
13.2
84.5
85
74
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.2
81.7
82
71
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
13.4
68.0
67
56
H02AB02
ATC
dexamethasone; systemic
4.9
59.5
164
431
G40.9
ICD-10 Finland
Epilepsy, unspecified
9.4
58.2
74
89
AA1AD
NOMESCO Finland
CT of head and brain
3.6
51.4
304
1347
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
12.0
50.0
52
47
XCK00
NOMESCO Finland
Perimetry
5.8
49.6
102
206
N03AB02
ATC
phenytoin; systemic
14.2
49.0
46
35
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
13.3
48.4
47
38
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
11.3
47.9
52
50
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
13.4
47.5
46
37
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.7
45.0
121
307
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
39.3
164
567
D32.03
ICD-10 Finland
Benign meningioma in ventricles
135.1
36.1
38
*
ZXC95
NOMESCO Finland
Use of surgical navigator
11.5
35.9
38
35
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
356.7
34.3
34
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
185.6
34.1
35
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
180.0
33.1
34
*
N03AF02
ATC
oxcarbazepine; oral
6.6
32.0
54
89
N03AF01
ATC
carbamazepine; oral, rectal
4.7
30.5
76
179
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
112.6
30.0
32
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
7.5
29.2
43
61
8000/0-C70.0
ICD-O-3
Neoplasm, benign of cerebral meninges
34.7
28.1
36
11
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
105.2
27.9
30
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.7
26.8
52
98
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.6
26.8
35
43
N03AG01
ATC
valproic acid; systemic, rectal
4.4
26.7
72
180
R51.80
ICD-10 Finland
Headache
2.9
24.2
140
573
D32.05
ICD-10 Finland
Cerebral meninges
47.0
22.5
27
6
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
22.0
166
774
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.4
21.6
87
287
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.5
20.9
53
126
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.4
20.5
54
132
H53.4
ICD-10 Finland
Visual field defects
6.4
20.0
34
56
9531/0-C70.0
ICD-O-3
Meningothelial meningioma of cerebral meninges
206.6
19.7
20
*
D32
ICD-10 Finland
Benign neoplasm of meninges
195.9
18.6
19
*
WX882
NOMESCO Finland
High dependency care
5.6
18.0
35
66
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
17.8
17
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
19.4
17.5
26
14
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
26.5
17.0
23
9
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
26.5
17.0
23
9
N75
ICPC
Benign neoplasm nervous system
+∞
16.7
16
*
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
92.7
16.6
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
16.0
183
1006
9539/1-C70.0
ICD-O-3
Atypical meningioma of cerebral meninges
+∞
15.7
15
*
8000/0-C70.9
ICD-O-3
Neoplasm, benign of meninges, NOS
+∞
15.7
15
*
ZXC40
NOMESCO Finland
Use of ultrasound
22.9
14.3
20
9
N03AX18
ATC
lacosamide; systemic
16.3
14.0
22
14
9532/0-C70.0
ICD-O-3
Fibrous meningioma of cerebral meninges
143.2
13.5
14
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
13.4
92
403
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
10.4
13.1
25
25
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
14.5
12.8
21
15
H53.2
ICD-10 Finland
Diplopia
4.0
12.5
36
94
AAK00
NOMESCO Finland
Cranioplasty
132.7
12.5
13
*
H47.2
ICD-10 Finland
Optic atrophy
27.3
12.1
16
6
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
+∞
11.5
11
*
Z2445
NOMESCO Finland
Psychologist
4.3
11.5
30
73
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
11.4
148
839
ZX050
NOMESCO Finland
Stereotactic radiotherapy
17.5
11.2
17
10
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
18.2
10.8
16
9
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
61.1
10.7
12
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
11.5
10.6
19
17
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
10.6
54
203
Z3231
NOMESCO Finland
Registered nurse
1.9
10.4
181
1130
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
23.8
10.3
14
6
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
23.8
10.3
14
6
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
11.6
10.1
18
16
G40.10
ICD-10 Finland
Simple partial seizures
11.6
10.1
18
16
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
9.9
245
1692
N18
ICPC
Paralysis/weakness
4.5
9.9
24
55
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.3
9.8
38
122
22520
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
55.9
9.7
11
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.5
97
500
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
101.6
9.4
10
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
101.6
9.4
10
*
N76
ICPC
Neoplasm nervous system unspecified
30.6
9.4
12
*
WF002
NOMESCO Finland
Radical radiotherapy
3.0
8.7
39
137
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
8.6
42
154
WF099
NOMESCO Finland
Other radiotherapy
16.6
8.6
13
8
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
10.2
8.6
16
16
9537/0-C70.0
ICD-O-3
Transitional meningioma of cerebral meninges
28.0
8.5
11
*
2152
FHL
Extraction, big brain
28.0
8.5
11
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.1
8.4
81
408
H02AB09
ATC
hydrocortisone; systemic
4.1
8.4
23
58
D33.0
ICD-10 Finland
Benign neoplasm: Brain, supratentorial
+∞
8.3
8
*
183
Kela drug reimbursment
Lamotrigin and topiramate
9.6
8.3
16
17
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.9
8.1
24
64
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.9
225
1593
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
7.8
76
384
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
8.2
7.6
16
20
G91.1
ICD-10 Finland
Obstructive hydrocephalus
18.6
7.6
11
6
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
9.0
7.6
15
17
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.4
7.5
51
222
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
7.4
109
637
C70.0
ICD-10 Finland
Malignant neoplasm: Cerebral meninges
81.1
7.4
8
*
N03AX09
ATC
lamotrigine; oral
3.0
7.4
32
110
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
7.3
7
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.2
7.3
29
95
F05.9
ICD-10 Finland
Delirium, unspecified
3.8
7.2
22
60
G93.0
ICD-10 Finland
Cerebral cysts
20.3
7.2
10
5
WX872
NOMESCO Finland
Intensive care
2.8
7.1
36
135
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.2
7.1
13
13
L28
ICPC
Limited function/disability (L)
1.7
6.9
143
926
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
6.8
52
238
G91.0
ICD-10 Finland
Communicating hydrocephalus
11.1
6.8
12
11
R4130
NOMESCO Finland
Speech therapy
3.5
6.8
23
68
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
6.7
171
1167
XKD00
NOMESCO Finland
Uroflowmetry
2.0
6.7
80
436
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
6.0
6.6
17
29
G50.1
ICD-10 Finland
Atypical facial pain
3.7
6.5
20
55
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
6.5
126
799
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
70.6
6.4
7
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
70.6
6.4
7
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
14.5
6.4
10
7
R4110
NOMESCO Finland
Physiotherapy
1.6
6.4
173
1197
A28
ICPC
Limited function/disability NOS
1.7
6.3
136
886
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
6.3
80
445
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.3
212
1545
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
6.3
6
*
N06AB04
ATC
citalopram; systemic
1.7
6.3
139
914
TAB00
NOMESCO Finland
Lumbar puncture
2.6
6.2
35
139
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
6.2
72
388
ZXD05
NOMESCO Finland
Urgent procedure
1.6
6.2
171
1189
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.8
6.1
18
48
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
46
37
13.39
47.45
1.5
2.1
—
—
—
0
0
157
824
2.23
15.30
2.2
1.8
28.65
29.19
s
0.69
152
795
29
56
5.39
14.52
2.3
1.2
—
—
—
0
0
269
1771
1.95
13.92
2.8
2.1
247.53
220.42
u/l
0.11
260
1685
386
2881
1.97
13.61
7.6
6.9
1.21
1.22
mmol/l
0.61
346
2482
42
116
3.82
13.54
1.8
1.2
267.88
12.49
e6/l
0.48
33
85
42
118
3.75
13.21
1.9
1.3
998.83
173.24
e6/l
0.79
36
90
44
137
3.39
11.88
1.6
1.2
1085.50
477.77
mg/l
1.75
44
129
403
3153
1.87
11.14
6.3
4.8
6.78
6.71
mmol/l
0.21
388
2996
103
524
2.17
10.53
2.4
1.9
373.19
385.81
nmol/l
0.21
96
485
21
24
9.03
10.35
2.3
2.3
60.00
53.24
umol/l
0.29
16
19
120
653
2.05
10.27
6.7
7.0
0.84
1.10
mmol/l
0.36
93
551
196
1293
1.77
9.17
2.4
2.4
—
—
—
0
0
199
1322
1.76
9.07
4.1
3.9
92.06
90.26
%
0.49
194
1292
336
2597
1.68
8.60
13.7
15.4
1.23
1.26
inr
0.44
293
2153
19
26
7.51
8.50
2.4
1.2
—
—
—
0
0
313
2407
1.64
7.92
2.9
2.8
—
—
estimate
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
153
2.73
7.62
2.2
2.4
0.39
0.35
iu/ml
0.29
23
87
45
187
2.52
7.28
1.7
1.8
—
—
—
0
0
330
2615
1.59
7.05
7.0
6.0
1.20
1.21
mmol/l
1.81
311
2385
46
203
2.37
6.56
1.7
1.9
—
—
—
0
0
227
1697
1.55
5.96
2.8
2.5
73.77
65.64
u/l
0.15
210
1558
279
2186
1.52
5.87
5.1
4.1
24.04
76.00
ng/l
1.14
222
1643
346
2863
1.50
5.44
6.7
6.3
12.63
11.20
umol/l
0.42
329
2717
353
2965
1.47
4.93
10.2
9.4
4.04
4.11
e9/l
0.24
319
2578
136
940
1.58
4.91
2.0
1.9
—
—
—
0
0
130
909
1.55
4.43
2.7
3.1
0.83
0.81
mmol/l
0.75
118
848
75
460
1.72
4.31
2.5
2.6
4.30
6.06
ug/l
0.78
61
402
57
333
1.79
3.88
1.6
1.7
—
—
—
0
0
67
418
1.68
3.63
2.6
3.4
178.18
223.56
ng/l
0.38
59
387
59
361
1.70
3.44
9.5
8.4
0.61
0.65
%
0.48
59
356
15
53
2.88
3.38
1.1
1.1
—
—
—
0
0
82
550
1.57
3.33
8.8
7.4
121.93
119.75
g/l
0.49
82
541
49
292
1.74
3.15
1.2
1.4
—
—
—
0
0
13
41
3.22
3.07
1.2
1.1
—
—
—
0
0
29
147
2.02
3.05
1.9
1.5
—
—
—
0
0
142
1084
1.41
3.03
5.0
4.1
271.51
304.28
ng/l
0.05
109
875
59
377
1.63
2.94
9.5
8.0
1.28
1.28
%
0.01
59
371
190
1537
1.35
2.82
3.7
3.3
0.38
0.48
e6/l
0.24
151
1139
289
2485
1.32
2.81
4.8
4.6
35.04
35.35
g/l
0.44
271
2320
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
28
3.61
2.79
1.1
1.1
—
—
—
0
0
310
2698
1.31
2.73
3.0
2.7
—
—
—
0
0
70
476
1.53
2.70
4.9
6.0
8.37
9.88
mmol/l
1.13
64
452
65
435
1.56
2.69
1.4
1.6
—
—
—
0
0
27
141
1.96
2.64
1.9
1.8
3.23
4.36
iu/l
0.61
12
51
14
55
2.58
2.63
2.0
2.3
—
—
—
0
0
34
194
1.80
2.56
1.2
1.2
—
—
—
0
0
100
739
1.42
2.55
4.2
4.9
1.00
1.04
mmol/l
0.74
89
670
11
37
3.01
2.50
1.2
1.3
—
—
—
0
0
11
37
3.01
2.50
1.2
1.3
—
—
—
0
0
215
1803
1.30
2.42
3.8
3.4
93.97
95.94
e6/l
0.01
177
1393
439
4043
1.33
2.41
9.8
8.0
78.85
79.12
u/l
0.04
418
3799
425
3899
1.32
2.38
5.6
4.7
12.56
13.45
mm/h
0.62
402
3608
289
2531
1.28
2.28
2.8
2.5
76.98
80.32
nmol/l
1.28
257
2238
13
54
2.44
2.21
1.2
1.3
—
—
—
0
0
231
1976
1.28
2.18
3.7
3.4
—
—
—
0
0
8
25
3.23
2.10
2.5
3.3
422.88
733.24
u/ml
—
8
25
9
31
2.93
2.08
1.2
1.1
—
—
—
0
0
171
1416
1.29
2.07
2.6
2.3
2.67
3.05
mg/l
1.46
146
1208
220
1883
1.27
2.04
3.6
3.1
1858.56
1362.66
ng/l
0.61
185
1608
6
15
4.03
2.04
1.0
1.3
—
—
—
0
0
94
715
1.37
2.04
1.9
1.8
—
—
—
0
0
12
50
2.43
2.03
1.2
1.1
—
—
—
0
0
154
1261
1.30
2.03
2.9
2.7
4.75
6.57
e6/l
1.19
144
1161
129
1034
1.32
1.98
1.7
1.7
942.06
1185.94
nmol/l
2.70
94
764
435
4050
1.28
1.89
5.8
4.5
14.85
14.96
pmol/l
0.35
409
3675
45
302
1.53
1.89
1.3
1.4
—
35.30
—
0
22
352
3206
1.24
1.82
3.6
3.3
58.76
48.24
u/l
0.64
329
2984
282
2509
1.24
1.81
2.4
2.2
100.36
97.88
pmol/l
0.33
135
1256
200
1714
1.25
1.80
1.7
1.7
19.22
21.05
nmol/l
1.03
169
1418
230
2004
1.24
1.78
3.3
3.3
2.35
2.36
mmol/l
1.16
209
1799
37
241
1.57
1.78
2.1
1.8
1.55
2.35
ug/l
0.22
31
215
79
599
1.37
1.76
2.7
2.6
5.26
7.22
umol/l
1.58
67
526
6
18
3.36
1.75
1.0
1.1
—
—
—
0
0
5
13
3.87
1.72
1.0
1.3
—
—
—
0
0
190
1636
1.24
1.62
5.0
4.4
0.00
0.00
estimate
0.50
71
563
73
556
1.36
1.59
3.5
3.5
—
—
—
0
0
24
146
1.67
1.53
3.8
2.1
3.27
3.74
g/l
1.19
24
141
177
1521
1.23
1.53
5.3
3.8
0.00
0.01
estimate
0.99
65
481
7
27
2.61
1.52
1.0
1.2
—
—
—
0
0
7
27
2.61
1.52
1.0
1.2
—
—
—
0
0
6
21
2.88
1.51
1.0
1.3
—
—
—
0
0
43
302
1.46
1.49
10.3
8.6
16.16
15.65
%
0.72
43
293
26
163
1.62
1.49
1.5
1.6
0.18
0.45
iu/ml
—
8
30
265
2384
1.20
1.42
3.3
3.0
114.30
119.43
ug/l
0.16
242
2198
107
875
1.27
1.42
3.3
3.1
2.26
2.88
e6/l
0.48
58
427
35
241
1.48
1.36
3.0
1.9
1.83
8.44
iu/ml
—
8
62
30
200
1.53
1.35
3.8
3.7
1.06
1.33
mmol/l
1.72
30
194
84
676
1.28
1.28
2.0
1.9
—
—
—
0
0
21
131
1.63
1.25
1.4
2.2
120.15
127.14
g/l
0.53
13
100
13
70
1.88
1.24
1.3
1.5
—
—
—
0
0
49
366
1.37
1.24
7.2
6.4
24.71
24.54
mmol/l
0.16
49
351
6
26
2.32
1.19
2.8
2.6
1.17
0.88
index
—
6
26
113
951
1.23
1.18
3.3
2.9
1.27
1.29
e6/l
0.02
64
506
21
134
1.59
1.16
3.1
3.1
12.09
1.61
index
0.47
11
71
7
30
2.35
1.12
2.6
2.1
—
—
—
0
0
312
2889
1.17
1.11
5.5
4.4
0.07
0.02
estimate
0.35
73
576
506
4884
1.25
1.11
24.3
17.1
23.15
23.75
mg/l
0.18
455
4075
306
2832
1.17
1.09
5.5
4.4
0.01
0.00
estimate
0.49
77
596
140
1219
1.19
1.04
1.8
1.7
439.79
24048548.01
pmol/l
0.99
120
998
9
46
1.97
1.04
1.2
1.2
—
—
—
0
0
308
2862
1.16
1.02
5.5
4.4
0.00
5.64
estimate
0.80
82
621
21
139
1.53
1.01
2.5
3.5
0.83
0.79
nmol/l
0.18
14
116
40
301
1.35
1.00
1.9
3.8
2.53
2.05
mmol/l
0.33
30
236
7
36
1.96
0.97
1.1
1.2
—
—
—
0
0
70
572
1.25
0.97
5.0
3.1
2.00
2.05
mmol/l
0.04
57
481
78
648
1.23
0.94
8.0
7.5
—
—
—
0
0
6
28
2.15
0.91
1.8
1.9
767.17
472.14
e6/l
—
6
22
61
495
1.26
0.90
2.4
3.0
65.17
66.75
g/l
0.78
54
455
234
2148
1.15
0.89
5.7
4.4
0.00
0.03
estimate
2.29
68
493
23
161
1.45
0.88
1.4
1.2
—
—
—
0
0
6
30
2.01
0.87
1.2
1.0
—
—
—
0
0
11
64
1.73
0.86
1.9
1.4
—
—
—
0
0
81
683
1.22
0.86
5.5
5.1
33.13
33.20
%
0.02
56
427
12
72
1.68
0.85
1.2
1.4
—
—
—
0
0
380
3982
0.87
0.85
29.9
21.5
13.81
13.78
%
0.16
380
3936
10
57
1.77
0.84
1.2
1.2
—
81.83
—
0
6
68
812
0.82
0.83
1.5
1.4
—
—
—
0
0
26
189
1.39
0.82
1.2
3.8
4.76
4.73
ratio
0.00
17
110
202
2199
0.88
0.80
1.9
2.0
1.40
1.32
mmol/l
0.92
175
1834
12
74
1.63
0.78
1.2
1.4
—
—
—
0
0
12
74
1.63
0.78
1.2
1.4
—
—
—
0
0
94
812
1.19
0.78
2.7
2.4
21.93
21.73
%
0.04
81
761
29
218
1.35
0.76
1.5
2.2
9.45
10.54
g/l
0.68
24
192
10
59
1.71
0.76
1.4
1.7
—
—
—
0
0
137
1225
1.15
0.75
3.0
2.8
2.45
2.46
mmol/l
1.34
116
1102
5
24
2.09
0.74
1.4
2.3
—
—
—
0
0
5
24
2.09
0.74
1.0
1.3
—
—
—
0
0
21
150
1.41
0.74
1.1
1.2
—
—
—
0
0
23
169
1.38
0.70
1.1
1.3
—
—
—
0
0
30
231
1.31
0.69
1.4
1.3
—
—
—
0
0
22
161
1.38
0.69
1.4
1.2
—
—
—
0
0
11
69
1.61
0.68
1.2
1.4
—
—
—
0
0
11
69
1.61
0.68
1.2
1.4
—
—
—
0
0
99
873
1.16
0.66
2.6
2.4
2.36
2.33
g/l
0.22
87
812
11
70
1.58
0.65
1.2
1.4
—
—
—
0
0
14
95
1.49
0.64
2.0
1.7
—
—
—
0
0
105
934
1.15
0.63
2.7
2.4
12.79
12.54
umol/l
0.13
92
867
480
4672
1.14
0.62
7.4
5.8
1.85
1.96
mu/l
0.97
449
4282
184
1700
1.12
0.61
3.5
3.1
26.80
31.52
u/l
2.61
174
1599
486
4736
1.15
0.61
22.6
16.9
77.05
76.17
ml/min/173m2
0.42
471
4425
10
64
1.57
0.59
1.4
1.6
—
—
—
0
0
6
35
1.72
0.58
7.7
3.2
0.67
1.06
%
—
6
35
6
37
1.63
0.55
3.5
1.8
—
—
—
0
0
20
151
1.34
0.54
2.6
2.3
11.25
12.91
mg/l
0.62
20
140
11
74
1.50
0.53
2.2
1.6
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
112
1016
1.13
0.51
6.4
5.6
3.12
2.78
ug/l
0.24
91
902
13
92
1.42
0.51
1.3
1.4
—
—
—
0
0
6
41
1.47
0.50
1.0
1.2
—
—
—
0
0
7
45
1.56
0.49
1.9
1.4
—
—
—
0
0
52
449
1.17
0.47
3.1
2.9
73.29
63.03
ml/min/173m2
0.58
17
196
132
1215
1.11
0.47
2.1
1.6
1.42
1.32
mg/l
0.16
100
956
103
936
1.12
0.46
1.4
1.3
3.96
14.45
u/ml
2.11
36
346
10
69
1.46
0.44
1.4
1.1
3.80
7.52
u/ml
—
5
27
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
2.74
—
0
5
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
5
36
1.39
0.38
1.2
1.3
87.20
77.19
umol/l
—
5
36
5
36
1.39
0.38
1.2
1.5
—
—
—
0
0
50
441
1.15
0.37
1.6
1.5
—
—
—
0
0
9
70
1.29
0.36
1.0
1.0
—
—
—
0
0
56
499
1.13
0.36
2.9
3.4
86.76
81.54
ng/l
0.17
51
436
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
55
492
1.13
0.34
2.5
2.4
29.85
35.98
u/l
0.76
47
407
14
177
0.79
0.33
1.3
1.6
—
—
—
0
0
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
14
176
0.79
0.32
1.1
1.5
—
—
—
0
0
6
47
1.28
0.32
1.2
1.2
—
—
—
0
0
16
129
1.25
0.30
1.9
1.6
—
—
—
0
0
14
111
1.27
0.30
8.6
6.8
107.50
105.07
mmol/l
1.10
14
103
10
130
0.77
0.29
1.0
1.2
0.82
0.89
g/l
—
10
130
29
251
1.16
0.29
1.1
1.0
—
—
—
0
0
25
214
1.18
0.28
1.3
2.5
0.37
1.20
g/l
0.97
20
182
16
194
0.82
0.28
2.6
3.0
—
—
—
0
0
8
64
1.25
0.27
1.4
1.1
—
—
—
0
0
14
113
1.24
0.27
1.5
1.3
—
—
—
0
0
14
113
1.24
0.27
1.5
1.3
—
—
—
0
0
143
1359
1.07
0.27
2.9
2.7
326.46
338.18
umol/l
0.73
123
1179
8
66
1.21
0.27
2.3
1.6
—
—
—
0
0
29
253
1.15
0.26
1.4
1.9
1.51
1.54
g/l
0.08
24
227
32
282
1.14
0.26
1.7
1.6
—
—
—
0
0
9
73
1.24
0.25
1.1
1.1
—
—
—
0
0
29
255
1.14
0.24
1.7
1.6
—
—
—
0
0
17
143
1.19
0.23
1.8
1.6
—
—
—
0
0
56
516
1.09
0.23
2.2
2.1
0.22
0.21
g/l
0.22
50
486
131
1249
1.06
0.23
5.5
4.7
1.02
1.02
kg/l
1.33
96
843
0
11
0.00
0.21
0.0
1.6
—
1.26
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
68
726
0.93
0.20
1.9
1.5
—
—
—
0
0
26
292
0.89
0.20
1.4
1.9
3.11
3.50
mmol/l
1.02
21
223
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.5
1.2
83.67
102.08
pmol/l
—
6
51
14
118
1.19
0.19
2.0
1.5
—
—
—
0
0
86
815
1.06
0.18
5.8
4.9
21.55
21.95
%
0.11
52
420
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
10
121
0.82
0.18
1.0
1.2
1.50
1.61
g/l
—
10
121
11
91
1.21
0.17
1.3
1.5
—
—
—
0
0
13
152
0.85
0.17
1.5
1.5
—
—
—
0
0
8
73
1.10
0.15
1.0
1.2
—
—
—
0
0
457
4613
0.96
0.14
4.8
4.4
1.29
1.27
mmol/l
0.21
420
4183
14
122
1.15
0.14
2.1
1.3
—
—
—
0
0
12
103
1.17
0.14
1.5
1.7
—
—
—
0
0
106
1022
1.05
0.13
1.5
1.3
61.21
36.39
iu/ml
0.46
37
335
520
5232
0.95
0.13
36.4
26.3
4.39
4.40
e12/l
0.30
514
5110
520
5232
0.95
0.13
36.5
26.3
256.31
251.09
e9/l
0.98
515
5128
11
127
0.86
0.12
1.7
1.7
—
—
—
0
0
10
85
1.18
0.12
1.1
1.3
0.52
22.42
nmol/l
—
10
78
63
603
1.05
0.11
3.2
4.2
12.55
15.33
ug/l
0.11
49
510
478
4808
0.97
0.09
6.0
5.6
5.92
5.99
mmol/l
0.50
441
4382
490
4926
0.97
0.08
6.5
6.3
2.60
2.68
mmol/l
0.72
457
4529
5
60
0.83
0.08
1.2
1.1
—
28.78
—
0
9
511
5133
0.97
0.08
15.8
12.7
25.79
24.21
u/l
0.61
499
4967
7
68
1.03
0.08
1.9
3.9
—
—
—
0
0
469
4716
0.97
0.07
7.9
6.9
40.25
39.72
mmol/mol
0.57
439
4381
8
75
1.07
0.07
3.5
2.9
—
1122.83
—
0
6
58
600
0.96
0.07
4.3
3.3
0.78
0.85
ug/l
0.37
42
408
484
4816
1.03
0.07
5.5
5.3
1.50
1.53
mmol/l
0.77
448
4413
123
1207
1.02
0.06
1.3
1.3
1.43
1.58
u/ml
0.06
24
324
16
148
1.08
0.06
1.9
1.7
—
—
—
0
0
182
1844
0.98
0.06
3.3
3.3
6.64
6.81
mmol/l
0.20
153
1557
13
121
1.08
0.03
1.3
1.1
—
—
—
0
0
485
4837
1.01
0.03
5.6
5.4
4.59
4.66
mmol/l
0.80
453
4459
13
122
1.07
0.02
2.5
2.2
12.89
60.39
ug/min
—
8
69
183
1839
0.99
0.01
4.0
4.1
8.06
7.60
mg/mmol
0.04
112
1115
10
106
0.94
0.01
2.4
1.5
—
—
—
0
0
12
126
0.95
0.00
2.2
1.5
—
—
—
0
0
14
136
1.03
0.00
1.4
1.3
—
—
—
0
0
19
194
0.98
0.00
1.5
1.3
272.05
296.48
ug/g
0.15
13
118
14
143
0.98
0.00
1.4
1.7
—
—
—
0
0
17
173
0.98
0.00
1.4
1.4
0.26
0.34
mg/l
—
10
71
11
112
0.98
0.00
5.1
1.9
75.88
59.22
%
1.36
11
112
34
342
0.99
0.00
1.1
1.2
139.72
146.34
u/ml
0.04
11
142
11
109
1.01
0.00
1.4
1.5
—
—
—
0
0
12
119
1.01
0.00
2.0
2.6
13.65
7.89
pmol/l
1.15
12
119
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
7.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
6.9
—
10.14
—
0
8
5
53
0.94
-0.00
1.6
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
53
0.94
-0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
106.47
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
6.44
—
0
5
5
53
0.94
-0.00
1.6
1.6
—
—
—
0
0
5
53
0.94
-0.00
3.2
1.6
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.4
0.19
0.20
nmol/l
—
5
37
6
61
0.98
-0.00
1.2
1.3
—
162.52
—
0
22
16
160
1.00
-0.00
2.1
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MENINGES_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MENINGES_NOS | 1.849 [1.64, 2.08] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.382 |
During the follow-up period (1.1.1998 — 31.12.2019), 1164 out of 2919 females with CD2_BENIGN_MENINGES_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MENINGES_NOS | 1.959 [1.64, 2.35] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.033 |
During the follow-up period (1.1.1998 — 31.12.2019), 447 out of 1022 males with CD2_BENIGN_MENINGES_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MENINGES_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.178% | 0.389% |
| 5 | 0.971% | 2.184% |
| 10 | 2.724% | 5.914% |
| 15 | 5.12% | 10.892% |
| 20 | 9.169% | 19.39% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MENINGES_NOS – Beningn neoplasm: Meninges, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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