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Malignant neoplasm of bone and articular cartilage

DOID Endpoint Browser PheWeb

C3_BONE_CARTILAGE

bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

412

6. Filter based on genotype QC (FinnGen only)

362

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4

Case counts by codes

↥

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 362 160 202
Unadjusted period prevalence (%) 0.08 0.06 0.09
Median age at first event (years) 54.77 51.98 56.98

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
372
Matched controls
3720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
122.8
219.0
112
13
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
250.9
145.4
141
9
130
Kela drug reimbursment
Malignant tumour
+∞
130.0
117
*
A04AA01
ATC
ondansetron; systemic, rectal
28.4
127.0
91
42
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
+∞
114.7
104
*
JN4AD
NOMESCO Finland
Body CT examination
15.0
113.1
116
109
JN4BD
NOMESCO Finland
Extensive body CT
17.0
109.7
102
81
N02AA05
ATC
oxycodone; systemic
9.7
102.0
162
273
XX3DW
NOMESCO Finland
Time consuming IT work
16.4
97.6
91
72
XW000
NOMESCO Finland
Bone marrow biopsy
26.9
91.0
65
29
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
83.6
77
*
L03AA02
ATC
filgrastim; parenteral
485.8
81.3
78
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
79.0
73
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
72.3
67
*
A03FA01
ATC
metoclopramide; systemic, rectal
7.6
72.1
132
251
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
25.0
71.4
52
24
Z51.5
ICD-10 Finland
Palliative care
13.5
69.6
71
64
WW500
NOMESCO Finland
Blood transfusion
20.6
69.4
55
31
NF3AA
NOMESCO Finland
Femur X-ray examination
16.7
63.5
56
39
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.8
59.6
66
67
L03AA13
ATC
pegfilgrastim; parenteral
653.8
58.3
56
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
21.2
57.9
45
24
TPX10
NOMESCO Finland
Implantation of vascular injection port
21.2
57.9
45
24
A04AA02
ATC
granisetron; systemic, transdermal
626.4
56.1
54
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
55.6
52
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
53.4
50
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.4
52.5
69
88
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
150.6
50.2
52
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.8
49.5
201
737
C90.0
ICD-10 Finland
Multiple myeloma
+∞
48.0
45
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
17.1
46.7
40
26
GD1AD
NOMESCO Finland
Thorax CT examination
8.8
46.5
64
86
JN4CD
NOMESCO Finland
Very extensive body CT
20.9
46.3
36
19
WF002
NOMESCO Finland
Radical radiotherapy
137.3
46.0
48
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
8.0
45.8
69
103
B01AB10
ATC
tinzaparin; parenteral
6.7
44.8
82
151
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
12.7
43.9
45
40
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
43.6
41
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
468.4
43.1
42
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
42.5
40
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.5
41.4
257
1239
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
41.4
39
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
41.4
39
*
B01AB05
ATC
enoxaparin; parenteral
4.1
39.5
175
661
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
38.2
36
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
9.4
37.7
48
58
WX408
NOMESCO Finland
General anesthesy, balanced
4.1
37.7
152
535
WX302
NOMESCO Finland
Thoracal epidural anesthesy
12.7
37.5
38
33
WX402
NOMESCO Finland
General anaesthesia
4.3
37.1
131
418
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
37.1
35
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
37.1
35
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
9.4
36.4
46
55
N03AX16
ATC
[U] pregabalin
4.1
36.1
145
506
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
36.0
34
*
R4110
NOMESCO Finland
Physiotherapy
3.8
35.0
164
634
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
34.9
33
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
34.7
84
198
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
33.5
121
389
WZC30
NOMESCO Finland
Teaching
4.6
33.1
96
262
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
32.8
31
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
31.7
30
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
30.6
29
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
6.9
30.6
51
84
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
72.1
29.4
33
5
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
28.8
88
248
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
34.1
28.7
37
12
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
28.5
27
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
7.5
27.8
42
62
ZX120
NOMESCO Finland
Intravenous
5.5
27.5
58
120
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
27.4
26
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
27.4
26
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
27.4
26
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
26.4
25
*
153
Kela drug reimbursment
Lenalidomid
+∞
26.4
25
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
10.1
24.7
29
31
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
24.2
23
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
24.2
23
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
24.2
23
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
133.6
23.9
25
*
329
Kela drug reimbursment
Lenalidomide
+∞
23.2
22
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
23.2
22
*
L04AX04
ATC
lenalidomide; oral
+∞
23.2
22
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
23.2
22
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.1
22.2
50
109
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
22.1
21
*
C41.49
ICD-10 Finland
Malignant tumor of the pelvic bones, sacrum and coccyx other or unspecified histology
+∞
22.1
21
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
21.0
20
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.3
20.6
60
161
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
20.0
19
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
20.0
19
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
77.5
19.9
22
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
19.9
70
215
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
19.9
145
687
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
210.7
19.7
20
*
N02BF02
ATC
pregabalin; oral
5.0
19.7
45
99
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
7.7
19.3
28
39
R50.9
ICD-10 Finland
Fever, unspecified
3.3
19.3
89
325
HA1AA
NOMESCO Finland
X-ray mammography
7.5
18.9
28
40
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
18.9
18
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
18.9
18
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
73.8
18.9
21
*
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
46.5
18.4
22
5
115
Kela drug reimbursment
Breast cancer
+∞
17.9
17
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
17.9
17
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
17.9
17
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.0
17.7
28
43
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
7.8
17.6
25
34
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.5
17.3
35
69
JN6AD
NOMESCO Finland
CT of torso and neck
33.3
17.2
22
7
9101
FHL
Bone biopsy
+∞
16.8
16
*
L71
ICPC
Malignant neoplasm musculoskeletal
+∞
16.8
16
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
16.8
16
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
16.8
16
*
A04AD12
ATC
aprepitant; systemic
+∞
16.8
16
*
C41.4
ICD-10 Finland
Malignant neoplasm: Pelvic bones, sacrum and coccyx
+∞
16.8
16
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
16.8
16
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
177.6
16.6
17
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.2
16.6
78
287
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
31.7
16.3
21
7
M05BX04
ATC
denosumab; parenteral
5.0
16.0
36
78
NB6AA
NOMESCO Finland
Humerus X-ray examination
7.3
15.9
24
35
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
15.8
153
816
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
15.7
15
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
15.7
15
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
15.7
15
*
B01AB04
ATC
dalteparin; parenteral
5.5
15.6
31
60
J05AB01
ATC
aciclovir; systemic
2.7
15.4
102
451
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
30.1
15.3
20
7
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
59.2
14.9
17
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
14.8
68
246
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
14.7
61
207
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
83.5
14.7
16
*
9370/3-C41.4
ICD-O-3
Chordoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
14.7
14
*
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
14.7
14
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
155.9
14.6
15
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.3
14.3
39
99
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
44.3
14.2
17
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.3
14.1
58
196
ZXA05
NOMESCO Finland
Left side
2.5
14.0
114
556
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
55.5
13.9
16
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
55.5
13.9
16
*
M04AA01
ATC
allopurinol; systemic
3.0
13.8
69
261
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
78.1
13.7
15
*
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
13.6
13
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
13.6
13
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
13.6
13
*
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
13.6
13
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
13.6
13
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
13.6
13
*
A79
ICPC
Malignancy NOS
+∞
13.6
13
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
145.1
13.5
14
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
145.1
13.5
14
*
ZXE00
NOMESCO Finland
One hour or less
2.3
13.5
160
919
N02BE01
ATC
paracetamol; systemic, rectal
4.2
13.1
346
2824
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
13.0
86
378
ZXD05
NOMESCO Finland
Urgent procedure
2.3
12.8
132
711
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
12.8
59
213
J01MA12
ATC
levofloxacin; systemic
2.7
12.7
83
362
ZXE40
NOMESCO Finland
More than seven and less than nine hours
10.6
12.7
24
24
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
72.4
12.7
14
*
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
20.9
12.6
18
9
NK6AT
NOMESCO Finland
Bone biopsy with ultrasound guidance
+∞
12.6
12
*
9731/3-C41.2
ICD-O-3
Plasmacytoma, NOS, of vertebral column
+∞
12.6
12
*
9680/3-C41.4
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
12.6
12
*
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
+∞
12.6
12
*
R4190
NOMESCO Finland
Nutritional therapy
4.6
12.4
30
69
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.5
12.4
45
140
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.4
12.3
32
78
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
12.0
122
651
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
19.7
11.7
17
9
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.3
11.7
47
156
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.3
11.6
24
48
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
+∞
11.5
11
*
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
11.5
11
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
11.5
11
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
11.5
11
*
WW409
NOMESCO Finland
Other aferesis
+∞
11.5
11
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
11.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
C41.40
ICD-10 Finland
Pelvic bones, sacrum and coccyx
+∞
11.5
11
*
WZC15, ,
NOMESCO Finland
+∞
11.5
11
*
9731/3-C41.3
ICD-O-3
Plasmacytoma, NOS, of rib, sternum, clavicle and associated joints
+∞
11.5
11
*
C41.3
ICD-10 Finland
Malignant neoplasm: Ribs, sternum and clavicle
+∞
11.5
11
*
A06AH03
ATC
naloxegol; oral
36.3
11.3
14
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
11.1
153
916
D70.89
ICD-10 Finland
Neutropenic splenomegaly
44.7
11.0
13
*
TPX15
NOMESCO Finland
Removal of vascular injection port
44.7
11.0
13
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.4
10.8
41
131
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
10.8
77
349
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.5
10.7
27
64
J04AB02
ATC
rifampicin; systemic
14.8
10.6
17
12
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.6
10.6
36
107
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
113.1
10.5
11
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
113.1
10.5
11
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
113.1
10.5
11
*
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
10.5
10
*
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.5
10
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
10.5
10
*
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.5
10
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
10.5
10
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
10.5
10
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
10.5
10
*
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
10.5
10
*
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
+∞
10.5
10
*
159
Kela drug reimbursment
Pazopanib
+∞
10.5
10
*
9680/3-C41.2
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of vertebral column
+∞
10.5
10
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
10.5
10
*
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
10.5
10
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
10.5
10
*
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
12.5
10.5
18
15
WX002
NOMESCO Finland
Sedation and analgesia
2.4
10.3
85
410
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.7
10.2
24
54
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
10.1
57
229
N02AX02
ATC
tramadol; systemic, rectal
2.0
10.0
173
1117
A02BC02
ATC
pantoprazole; systemic
2.1
9.9
257
1916
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.3
9.9
26
64
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.5
9.9
35
107
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
8.2
9.8
21
27
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
11.8
9.7
17
15
NF1AA
NOMESCO Finland
Hip X-ray examination
2.9
9.6
49
187
NF3AD
NOMESCO Finland
Femur CT
30.9
9.5
12
*
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
+∞
9.4
9
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
9.4
9
*
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
9.4
9
*
M90.7*C90.0
ICD-10 Finland
Pathological fracture in multiple myeloma
+∞
9.4
9
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
9.4
9
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
9.4
9
*
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
9.4
9
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
9.4
9
*
ZX112
NOMESCO Finland
Subcutaneous
11.1
9.4
17
16
L28
ICPC
Limited function/disability (L)
2.3
9.3
88
449
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.0
9.2
27
72
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.0
9.2
43
156
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
37.7
9.1
11
*
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
37.7
9.1
11
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
37.7
9.1
11
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
37.7
9.1
11
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
37.7
9.1
11
*
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
6.9
8.8
21
32
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
8.7
90
476
B03XA02
ATC
darbepoetin alfa; parenteral
12.0
8.6
15
13
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.0
8.5
20
30
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
92.1
8.4
9
*
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
5.1
8.4
18
37
J01FF01
ATC
clindamycin; systemic
2.1
8.4
102
573
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.0
8.4
24
63
WW402
NOMESCO Finland
Leucoferesis
+∞
8.4
8
*
9731/3-C41.4
ICD-O-3
Plasmacytoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
8.4
8
*
Z89.6
ICD-10 Finland
Acquired absence of leg above knee
+∞
8.4
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
8.4
8
*
C41.2
ICD-10 Finland
Malignant neoplasm: Vertebral column
+∞
8.4
8
*
C41.20
ICD-10 Finland
Malignant tumor of the spine without histology
+∞
8.4
8
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
8.4
8
*
C40.10
ICD-10 Finland
Malignant tumor of the upper limb's short bones without histology
+∞
8.4
8
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
8.4
8
*
NFA20
NOMESCO Finland
Exploration of hip joint or femur
+∞
8.4
8
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
8.4
8
*
C41.41
ICD-10 Finland
Osteosarcoma of the pelvic bones, sacrum and coccyx
+∞
8.4
8
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
8.4
8
*
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
+∞
8.4
8
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
8.4
8
*
SPAT1153
SPAT
Removal of sutures
2.0
8.3
118
701
XX2RW, ,
NOMESCO Finland
17.7
8.1
12
7
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
8.0
34
116
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.9
8.0
24
65
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
8.0
30
95
R52.0
ICD-10 Finland
Acute pain
4.1
8.0
22
56
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
8.0
19
43
H02AB09
ATC
hydrocortisone; systemic
6.3
8.0
20
33
H02AB06
ATC
prednisolone; systemic
1.9
7.8
173
1187
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
46.0
7.7
9
*
ZZR30
NOMESCO Finland
Flap of muscle
46.0
7.7
9
*
ZXA00
NOMESCO Finland
Right side
2.0
7.7
104
605
9102
FHL
Trepanation or removal of the local bone process
18.8
7.6
11
6
L02BG04
ATC
letrozole; oral
12.2
7.6
13
11
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
12.2
7.6
13
11
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
7.6
54
242
HAB40
NOMESCO Finland
Wedge excision of mammary gland
25.6
7.6
10
*
R4120
NOMESCO Finland
Occupational therapy
3.0
7.6
34
120
AA1AA
NOMESCO Finland
Head X-ray examination
10.3
7.6
14
14
ZX121
NOMESCO Finland
Central venous catheter
81.7
7.4
8
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
8.6
7.4
15
18
C41.06
ICD-10 Finland
Chondrosarcoma of the skull or facial bones except maxilla
+∞
7.3
7
*
C49.29
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip other or unspecified tumor
+∞
7.3
7
*
C41.29
ICD-10 Finland
Malignant tumor of the spine other or unspecified histology
+∞
7.3
7
*
YN1AD
NOMESCO Finland
CT examination of extremities for dose design of radiotherapy
+∞
7.3
7
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
7.3
7
*
C40.0
ICD-10 Finland
Malignant neoplasm: Scapula and long bones of upper limb
+∞
7.3
7
*
C41.09
ICD-10 Finland
Malignant tumor of the skull or facial bones other or unspecified histology
+∞
7.3
7
*
C40.93
ICD-10 Finland
Malignant tumor in unspecified locations in the bones and articular cartilage of the extremities
+∞
7.3
7
*
343
Kela drug reimbursment
Pazopanib
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
7.3
7
*
WX1CG
NOMESCO Finland
Extensive total body MRI with high intensity magnet
+∞
7.3
7
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.3
7
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
7.3
7
*
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
+∞
7.3
7
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
7.3
7
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
+∞
7.3
7
*
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
16.1
7.3
11
7
NG4AD
NOMESCO Finland
Lower leg CT
30.7
7.2
9
*
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
30.7
7.2
9
*
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
20.5
7.2
10
5
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
7.1
164
1128
J05AB11
ATC
valaciclovir; oral
2.2
7.1
63
312
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.8
7.0
21
57
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
14.1
6.9
11
8
WX600
NOMESCO Finland
Single shot through catheter
14.1
6.9
11
8
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
6.9
162
1118
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.5
6.8
23
68
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
40.8
6.8
8
*
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
40.8
6.8
8
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
6.7
80
443
ZX108
NOMESCO Finland
Inhalation
23.0
6.7
9
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.7
6.7
38
153
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.6
6.7
22
64
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.8
6.6
33
124
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
8.9
6.6
13
15
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
10.3
6.6
12
12
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.4
6.5
24
75
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
6.5
21
60
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
5.9
6.5
17
30
S18
ICPC
Laceration/cut
1.8
6.5
177
1270
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
6.4
83
472
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
71.0
6.4
7
*
JAG60
NOMESCO Finland
Reconstruction of abdominal wall using prosthetic material
71.0
6.4
7
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
6.4
51
240
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
14.6
6.4
10
7
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
9.5
6.3
12
13
C41.0
ICD-10 Finland
Malignant neoplasm: Bones of skull and face
+∞
6.3
6
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
6.3
6
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
6.3
6
*
9731/3-C41.9
ICD-O-3
Plasmacytoma, NOS, of bone, NOS
+∞
6.3
6
*
XX1AD
NOMESCO Finland
Other CT-examination
+∞
6.3
6
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
6.3
6
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
6.3
6
*
116
Kela drug reimbursment
Prostate cancer
+∞
6.3
6
*
C40.23
ICD-10 Finland
Ewing's sarcoma in the long bones of the lower extremity
+∞
6.3
6
*
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
+∞
6.3
6
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
6.3
6
*
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
+∞
6.3
6
*
C40.12
ICD-10 Finland
Chondrosarcoma of the short bones of the upper extremity
+∞
6.3
6
*
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
+∞
6.3
6
*
C40.9
ICD-10 Finland
Malignant neoplasm: Bone and articular cartilage of limb, unspecified
+∞
6.3
6
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
6.3
6
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
6.3
6
*
NGR40
NOMESCO Finland
Extensive excision of tumor of knee or lower leg with repair
+∞
6.3
6
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
6.3
6
*
NBA20
NOMESCO Finland
Exploration of joint of shoulder or upper arm, open
+∞
6.3
6
*
C41.00
ICD-10 Finland
Malignant tumor of the skull or facial bone without histology
+∞
6.3
6
*
NK6DT
NOMESCO Finland
Bone biopsy with MRI guidance
+∞
6.3
6
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
27.2
6.3
8
*
N07BC02
ATC
methadone; systemic
27.2
6.3
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.8
6.2
140
949
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
6.1
158
1111
Z31.6
ICD-10 Finland
General counselling and advice on procreation
10.3
6.1
11
11
SPAT1229
SPAT
Assessment of need for aid
2.7
6.1
33
130

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
123
78
23.06
150.86
1.7
1.4
—
—
—
0
0
84
90
11.76
73.61
11.8
1.2
32.55
30.63
mg/l
0.05
76
80
84
90
11.76
73.61
11.9
1.2
38.79
42.96
mg/l
0.23
76
79
78
81
11.92
69.69
10.4
1.2
4.45
1.33
ratio
0.70
55
47
49
27
20.75
62.26
3.3
1.0
—
—
—
0
0
100
187
6.95
54.35
8.9
1.3
—
—
—
0
0
50
44
12.97
49.26
4.1
1.3
—
—
—
0
0
38
21
20.04
47.93
1.6
1.3
—
—
—
0
0
206
813
4.44
44.99
7.4
3.9
—
—
—
0
0
266
1283
4.77
43.68
9.5
4.4
34.10
36.15
g/l
6.27
258
1202
218
911
4.36
43.65
5.0
2.1
—
—
—
0
0
39
29
14.91
42.28
3.3
2.0
0.34
1.74
g/24h
1.30
23
18
215
918
4.18
41.10
3.2
1.7
—
—
—
0
0
181
686
4.19
40.99
5.4
2.1
—
—
—
0
0
286
1524
4.79
39.30
16.7
4.1
9.52
11.95
umol/l
6.37
279
1454
92
212
5.44
39.30
1.3
1.5
—
—
—
0
0
265
1366
4.27
37.40
18.4
7.0
1.21
1.21
mmol/l
0.21
251
1247
281
1530
4.42
36.14
21.4
7.1
1.20
1.21
mmol/l
0.91
248
1336
299
1702
4.86
36.13
27.1
6.8
4.13
4.25
e9/l
0.19
273
1476
259
1338
4.08
35.85
5.2
2.5
—
—
estimate
—
0
0
70
150
5.52
32.10
4.4
1.7
4.93
2.61
ug/l
1.17
53
111
209
997
3.50
31.37
13.0
6.0
—
—
—
0
0
278
1588
3.97
31.29
12.3
6.0
0.56
0.58
e9/l
0.86
253
1366
78
190
4.93
30.79
5.3
1.4
0.74
1.14
g/l
4.96
73
182
279
1623
3.88
29.94
12.5
6.1
1.57
1.87
e9/l
8.19
256
1431
276
1598
3.82
29.75
12.4
6.0
0.03
0.04
e9/l
4.95
250
1380
281
1650
3.87
29.54
13.9
6.2
0.18
0.21
e9/l
1.15
256
1440
88
244
4.41
29.46
1.4
1.1
—
—
—
0
0
259
1447
3.60
29.40
11.8
6.1
2.69
3.06
%
1.40
254
1364
259
1448
3.60
29.35
12.0
6.2
9.03
8.79
%
0.64
254
1369
125
450
3.68
28.89
2.6
1.9
—
—
—
0
0
108
365
3.76
27.27
11.8
9.1
0.82
1.12
mmol/l
0.35
90
306
255
1451
3.41
27.24
12.0
6.2
0.57
0.69
%
3.02
250
1366
109
372
3.73
27.11
11.7
9.0
7.41
7.41
ph
0.49
56
221
106
363
3.69
26.14
1.5
1.6
—
—
—
0
0
118
437
3.49
25.75
1.6
1.6
—
—
—
0
0
196
984
3.10
25.48
9.7
2.1
2.35
2.35
mmol/l
0.22
185
863
24
0
+∞
25.29
24.8
0.0
0.33
—
umol/l
—
24
0
31
9
37.40
24.69
2.3
1.0
—
—
—
0
0
331
2309
4.93
24.09
19.8
5.8
93.15
78.86
u/l
2.79
323
2153
178
879
2.97
23.32
10.0
3.4
7.40
7.40
ph
1.03
138
629
290
1881
3.46
22.99
12.6
5.2
6.56
6.72
mmol/l
0.81
281
1780
80
246
3.87
22.88
5.9
4.3
1.60
0.64
%
3.31
51
49
167
807
2.94
22.61
4.2
2.5
314.87
352.97
umol/l
4.59
156
708
74
229
3.79
20.86
5.7
4.2
0.96
0.43
%
1.82
45
44
238
1446
2.79
19.96
16.6
15.6
1.19
1.28
inr
2.23
211
1208
81
277
3.46
19.56
5.7
2.2
74.13
66.91
e9/l
1.13
67
201
71
237
3.47
17.71
6.2
4.4
0.20
0.08
%
0.93
41
40
23
9
27.11
17.11
1.2
1.8
—
—
—
0
0
125
589
2.69
16.87
6.1
2.0
2.48
2.43
mmol/l
3.24
118
517
26
16
17.37
16.80
3.5
3.1
33.03
39.72
%
0.87
26
16
111
500
2.74
16.29
5.6
2.1
29.79
29.61
s
0.12
106
487
42
102
4.51
16.29
18.1
9.2
1.23
1.46
mg/l
1.19
42
92
162
904
2.40
14.91
3.8
3.2
0.69
0.36
e6/l
0.35
122
644
20
8
26.30
14.84
1.4
1.0
—
—
—
0
0
23
15
16.25
14.60
3.7
3.2
14.83
12.07
%
0.32
23
15
23
15
16.25
14.60
3.8
3.3
73.35
69.33
%
0.25
23
15
99
448
2.65
14.19
18.3
6.9
104.30
104.45
mmol/l
0.10
99
448
78
317
2.85
13.73
19.6
9.2
—
—
—
0
0
85
368
2.70
13.22
2.0
1.7
—
—
—
0
0
65
244
3.02
13.17
7.0
4.6
0.37
0.00
%
0.49
35
32
217
1422
2.26
13.16
25.9
9.6
0.00
0.00
e9/l
1.11
184
1162
74
301
2.82
12.96
23.8
8.5
1.10
1.40
mmol/l
2.78
74
294
143
800
2.28
12.64
1.6
1.4
—
—
—
0
0
110
552
2.41
12.49
1.7
2.0
—
—
—
0
0
173
1053
2.20
12.37
4.4
3.3
44.65
98.50
e6/l
0.39
138
786
18
12
15.69
11.42
1.1
1.1
—
—
—
0
0
23
28
8.68
10.98
3.5
1.7
382.43
854.50
mg
1.06
23
28
182
1173
2.08
10.80
5.6
4.1
75.87
92.81
e6/l
0.21
142
809
151
911
2.11
10.66
20.5
4.5
—
—
—
0
0
61
249
2.73
10.51
5.5
5.5
7.43
7.41
ph
0.98
52
200
276
2105
2.21
10.12
5.6
4.5
—
3.91
—
0
5
109
606
2.13
9.33
4.6
2.9
558.17
548.75
mosm/kgh2o
0.18
103
522
124
724
2.07
9.32
3.5
2.6
4.86
5.24
e6/l
0.18
116
650
32
96
3.55
9.26
2.1
1.9
9.63
7.03
u/l
0.42
18
80
19
23
8.64
9.18
2.8
3.9
—
—
—
0
0
20
42
4.98
9.17
1.5
1.4
—
—
—
0
0
20
42
4.98
9.17
1.5
1.4
—
—
—
0
0
20
42
4.98
9.17
1.5
1.4
—
—
—
0
0
20
42
4.98
9.17
1.5
1.4
—
—
—
0
0
73
347
2.37
9.11
4.3
2.7
5.13
7.63
umol/l
1.46
67
307
12
5
24.72
8.96
1.7
3.8
37.67
26.80
%
—
12
5
12
5
24.72
8.96
1.7
3.8
4.75
6.00
%
—
12
5
14
10
14.49
8.76
1.9
2.4
30.36
209.80
e6/l
—
14
10
59
259
2.52
8.73
2.4
2.7
0.20
0.21
g/l
0.65
59
236
19
29
6.84
7.99
3.3
1.3
32.21
33.41
pg
0.46
19
29
23
62
3.89
7.75
5.1
2.7
59.25
58.03
%
0.16
23
62
15
18
8.63
7.39
5.0
2.1
700.30
552.46
e6/l
—
10
13
15
18
8.63
7.39
3.1
1.2
—
—
—
0
0
153
1023
1.84
7.37
5.0
3.3
1284.80
1336.11
ng/l
0.06
141
860
356
3175
3.82
7.31
45.3
17.3
139.18
139.79
mmol/l
4.22
351
3113
356
3177
3.80
7.26
45.9
17.3
3.94
3.99
mmol/l
2.68
350
3106
110
671
1.91
7.00
10.6
4.5
—
—
—
0
0
349
3094
3.07
6.90
40.4
13.7
30.17
23.79
mg/l
2.72
324
2449
178
1264
1.78
6.90
4.6
3.9
26.98
39.00
ng/l
1.47
148
908
22
63
3.65
6.82
1.4
1.4
—
—
—
0
0
18
33
5.68
6.69
1.8
3.2
—
—
—
0
0
137
907
1.81
6.67
4.1
3.2
—
—
—
0
0
145
981
1.78
6.54
3.3
2.4
50.79
62.08
u/l
1.39
140
914
17
42
4.19
6.42
5.2
3.2
3.95
4.40
e9/l
0.36
17
42
21
62
3.53
6.24
1.5
1.3
—
—
—
0
0
13
17
7.88
6.17
2.3
2.9
47.33
45.62
%
—
6
9
11
11
10.26
6.07
6.1
3.0
10.45
20.00
%
0.49
11
11
41
182
2.41
5.90
6.1
6.0
—
—
—
0
0
11
12
9.40
5.82
6.2
2.8
36.45
22.92
%
2.41
11
12
107
682
1.80
5.78
3.8
1.8
1.40
1.09
mg/l
0.64
89
517
88
528
1.87
5.78
4.0
3.1
3.30
1.92
e6/l
0.61
43
256
20
61
3.41
5.67
1.2
1.5
96.50
134.25
au/ml
—
8
22
213
1655
1.67
5.50
5.4
3.8
0.00
0.00
estimate
-0.00
48
323
124
837
1.72
5.45
2.3
2.4
2.63
2.75
mg/l
0.28
107
724
210
1635
1.65
5.30
5.4
3.8
0.00
0.00
estimate
-0.00
48
321
129
897
1.67
5.00
5.8
3.7
0.00
0.00
estimate
-0.00
46
299
68
396
1.88
4.85
4.1
2.7
3.35
4.56
e9/l
3.34
62
347
211
1668
1.61
4.83
5.4
3.8
0.00
0.01
estimate
0.50
47
303
40
193
2.20
4.76
4.6
6.8
—
—
—
0
0
106
708
1.70
4.75
4.5
1.4
2.21
2.45
g/l
0.50
86
421
49
259
2.03
4.62
11.5
3.6
7.38
7.35
ph
0.68
38
176
15
37
4.18
4.45
1.5
1.1
—
—
—
0
0
9
12
7.65
4.38
3.1
2.2
735.78
594.33
u/ml
—
9
12
67
403
1.81
4.30
1.5
1.5
—
—
—
0
0
16
51
3.23
4.26
1.6
1.2
—
—
—
0
0
64
383
1.81
4.17
22.0
4.9
1.79
1.70
mmol/l
0.08
59
325
65
391
1.80
4.17
21.8
5.0
7.38
7.38
ph
0.11
39
239
22
87
2.62
4.04
1.5
1.5
16236.37
10693.29
e6/l
0.49
16
66
11
22
5.12
4.03
1.3
1.1
—
—
—
0
0
11
23
4.89
3.90
1.1
1.1
—
—
—
0
0
9
15
6.12
3.84
4.7
1.0
41.21
40.56
g/l
—
9
15
6
5
12.16
3.77
1.2
1.0
—
—
—
0
0
13
34
3.92
3.73
1.2
1.2
31.19
25.37
g/l
0.70
13
27
171
1340
1.51
3.72
4.3
3.4
6.41
6.19
ph
1.81
97
748
53
311
1.82
3.68
4.0
1.9
370.53
379.32
nmol/l
0.15
53
290
352
3279
2.37
3.64
26.2
10.1
28.64
26.64
u/l
0.89
346
3167
161
1257
1.50
3.51
5.7
3.6
0.04
0.00
estimate
0.43
46
264
24
108
2.31
3.40
2.8
1.8
17.55
22.37
iu/l
0.29
15
94
15
53
2.91
3.40
3.1
1.6
—
—
—
0
0
13
38
3.51
3.34
1.7
1.5
17.06
27.41
ng/l
1.35
13
38
40
225
1.87
3.18
6.0
3.3
—
—
—
0
0
346
3226
2.04
3.16
29.3
12.3
—
—
—
0
0
20
86
2.40
3.13
1.4
1.1
—
—
—
0
0
9
20
4.58
3.13
1.2
1.2
—
—
—
0
0
19
82
2.39
2.96
1.5
1.3
246.56
321.60
ug/g
—
9
47
18
77
2.41
2.86
3.3
2.6
3.08
2.07
index
0.25
13
44
174
1423
1.42
2.80
2.7
2.8
77.70
76.68
nmol/l
0.19
162
1280
89
644
1.50
2.71
3.8
4.1
41.33
474.42
ng/l
2.90
72
505
30
162
1.93
2.71
1.3
1.3
—
—
—
0
0
11
36
3.12
2.58
2.0
1.9
3.19
107.64
u/ml
0.50
11
36
9
221
0.39
2.53
1.0
1.3
—
—
—
0
0
15
63
2.44
2.49
4.3
3.8
—
—
—
0
0
13
51
2.61
2.47
1.1
1.0
—
—
—
0
0
9
27
3.39
2.40
1.2
1.1
—
—
—
0
0
43
270
1.67
2.39
1.9
1.9
0.00
0.00
estimate
—
5
61
5
8
6.32
2.38
1.4
1.3
0.67
0.61
mmol/l
—
5
8
7
17
4.18
2.37
1.0
1.6
—
—
—
0
0
175
1463
1.37
2.35
4.0
3.0
371.43
114.99
ug/l
1.31
168
1368
16
73
2.25
2.24
1.6
1.2
—
—
—
0
0
13
54
2.46
2.22
2.8
4.1
8.52
10.50
pmol/l
0.28
13
54
5
9
5.61
2.22
1.2
1.0
—
—
—
0
0
5
9
5.61
2.22
6.4
1.3
8.56
23.34
u/l
—
5
9
47
310
1.59
2.17
1.5
1.4
—
—
—
0
0
16
75
2.18
2.11
1.1
1.2
—
—
—
0
0
357
3421
2.08
2.11
57.7
20.7
6.77
6.68
e9/l
0.12
349
3340
357
3421
2.08
2.11
57.6
20.7
245.20
246.44
e9/l
0.12
349
3349
357
3421
2.08
2.11
57.6
20.7
4.25
4.56
e12/l
17.85
349
3340
269
2429
1.39
2.11
4.9
4.0
15.00
14.86
pmol/l
0.40
247
2224
8
25
3.25
2.10
1.3
1.1
—
—
—
0
0
13
56
2.37
2.07
1.5
2.1
5.08
5.20
mmol/24h
0.05
13
51
43
281
1.60
2.07
2.4
2.0
44.33
35.48
u/l
0.42
30
229
45
299
1.57
2.02
2.6
2.4
11.06
15.50
nmol/l
2.98
39
278
6
16
3.79
1.94
2.5
1.1
141.33
168.73
mmol/24h
—
6
16
20
349
0.55
1.88
1.3
1.6
—
—
—
0
0
32
199
1.67
1.87
24.8
4.0
0.62
0.63
%
0.07
32
199
96
1197
0.73
1.86
3.3
3.3
—
—
—
0
0
22
123
1.84
1.84
5.5
3.4
137.15
258.23
mg/l
1.51
13
48
9
35
2.61
1.81
1.4
1.2
—
—
—
0
0
32
202
1.64
1.78
24.8
4.0
1.28
1.22
%
0.17
32
202
6
18
3.37
1.75
1.0
1.3
—
—
—
0
0
6
18
3.37
1.75
2.0
2.2
0.50
0.89
index
—
6
18
0
47
0.00
1.71
0.0
1.0
—
6.36
—
0
21
0
49
0.00
1.69
0.0
1.0
—
1.85
—
0
24
8
31
2.61
1.67
1.0
1.2
—
—
—
0
0
20
113
1.81
1.64
1.4
1.2
—
—
—
0
0
231
2079
1.29
1.61
3.6
3.4
54.09
45.46
u/l
0.84
221
1967
8
32
2.53
1.60
4.4
1.7
82.09
91.23
%
—
8
32
0
42
0.00
1.53
0.0
1.0
—
0.97
—
0
14
5
15
3.36
1.53
2.4
1.4
0.60
3.87
u/field
—
5
8
17
94
1.85
1.50
3.3
1.8
—
—
—
0
0
166
1445
1.27
1.47
2.0
2.1
89.80
95.82
pmol/l
0.74
92
747
9
38
2.40
1.46
69.4
9.5
8.76
11.44
%
—
9
38
7
28
2.53
1.46
1.3
1.2
83.57
107.18
pmol/l
—
7
28
7
28
2.53
1.46
1.0
1.2
—
—
—
0
0
117
980
1.28
1.40
1.8
1.6
19.88
19.92
nmol/l
0.01
108
838
139
1191
1.27
1.39
4.6
4.2
2.97
1.90
ug/l
0.63
127
1060
9
41
2.22
1.38
1.6
1.2
—
—
—
0
0
96
786
1.30
1.37
5.4
3.8
1.02
1.02
kg/l
0.49
69
516
5
18
2.80
1.29
1.4
3.8
56.20
101.25
ug/l
—
5
18
17
100
1.73
1.25
1.2
1.1
—
—
—
0
0
6
26
2.33
1.19
1.3
1.7
17.68
16.60
%
—
6
26
17
271
0.61
1.19
1.4
1.3
—
—
—
0
0
38
278
1.41
1.13
4.0
2.4
0.97
0.26
e6/l
0.97
38
264
106
900
1.25
1.12
5.3
3.2
0.00
0.00
estimate
-0.00
43
260
5
21
2.40
1.09
1.2
1.0
1735.40
1746.71
miu/ml
—
5
21
8
41
1.97
1.09
1.0
1.1
—
—
—
0
0
55
431
1.32
1.08
1.3
1.2
—
—
—
0
0
307
2924
1.29
1.05
5.8
5.0
2.03
1.91
mu/l
0.80
285
2695
67
544
1.28
1.02
1.6
1.7
1460.69
1205.95
nmol/l
0.95
49
413
14
84
1.69
0.99
4.6
4.4
—
—
—
0
0
120
1364
0.82
0.99
1.9
2.0
1.39
1.33
mmol/l
0.28
100
1163
0
31
0.00
0.97
0.0
1.3
—
—
—
0
0
0
31
0.00
0.97
0.0
1.2
—
10.16
—
0
5
26
351
0.72
0.84
1.4
1.6
—
—
—
0
0
6
114
0.52
0.84
3.7
1.7
—
—
—
0
0
43
536
0.78
0.81
1.2
1.3
40.43
9.27
u/ml
0.52
12
209
117
1045
1.17
0.72
2.8
2.3
327.51
306.65
u/l
0.06
110
990
283
2941
0.84
0.69
6.5
6.7
38.84
39.69
mmol/mol
0.88
260
2765
20
144
1.41
0.69
1.5
1.8
1.18
8.21
iu/ml
—
5
39
5
28
1.80
0.66
1.6
1.6
7.50
8.07
mmol/l
—
5
28
8
51
1.58
0.61
5.5
2.8
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
0.23
—
0
5
14
97
1.46
0.60
1.5
1.3
367.93
500.63
mg/l
1.10
14
90
8
53
1.52
0.58
1.0
1.1
—
—
—
0
0
8
53
1.52
0.58
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
0.27
—
0
10
0
23
0.00
0.58
0.0
1.0
—
0.20
—
0
5
14
99
1.43
0.55
1.4
1.7
228.21
307.60
mu/l
1.36
14
90
6
38
1.59
0.54
1.2
1.3
—
—
—
0
0
50
583
0.84
0.54
1.4
1.3
75.71
34.35
iu/ml
0.33
16
178
11
158
0.69
0.54
2.0
1.5
—
—
—
0
0
11
158
0.69
0.54
2.7
1.5
—
—
—
0
0
6
39
1.55
0.53
2.0
2.3
—
—
—
0
0
12
84
1.44
0.50
1.3
1.3
3.71
3.76
mmol/l
0.06
12
78
7
109
0.64
0.49
1.3
1.1
—
—
—
0
0
7
45
1.57
0.49
1.0
1.2
—
—
—
0
0
13
93
1.41
0.49
1.3
1.1
—
—
—
0
0
16
120
1.35
0.47
1.5
1.4
—
—
—
0
0
6
91
0.65
0.43
1.0
1.1
1.40
1.53
g/l
—
6
91
11
150
0.73
0.42
2.0
1.5
—
—
—
0
0
5
33
1.52
0.41
1.4
2.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
149.82
—
0
17
12
159
0.75
0.39
1.9
1.5
—
—
—
0
0
23
279
0.81
0.39
1.1
1.2
—
—
—
0
0
75
824
0.89
0.38
1.2
1.4
1.67
1.55
u/ml
0.06
22
222
12
158
0.75
0.38
1.9
1.5
—
—
—
0
0
49
436
1.14
0.34
1.2
1.4
232.00
508.69
titre
—
10
99
15
118
1.28
0.34
1.8
1.5
1.15
1.18
g/l
0.13
15
111
13
166
0.78
0.34
1.0
1.1
—
—
—
0
0
6
45
1.34
0.34
2.0
2.2
1.22
1.20
mmol/l
—
6
45
6
86
0.69
0.33
1.0
1.1
—
0.68
—
0
12
6
46
1.31
0.33
2.0
2.2
4.12
4.11
mmol/l
—
6
46
6
46
1.31
0.33
2.0
2.2
107.17
105.87
mmol/l
—
6
46
297
2906
1.11
0.32
4.2
4.4
1.27
1.28
mmol/l
0.03
271
2681
19
157
1.22
0.30
2.4
2.4
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
18.74
—
0
20
72
665
1.10
0.28
1.6
1.8
422.87
20893277.53
pmol/l
0.50
55
560
8
62
1.30
0.28
1.1
1.0
—
—
—
0
0
28
246
1.15
0.24
4.8
2.4
6.17
6.07
ph
0.28
23
160
7
93
0.75
0.22
1.7
1.1
0.98
0.88
g/l
—
7
93
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
9.24
—
0
11
0
10
0.00
0.21
0.0
9.3
—
26.31
—
0
10
0
10
0.00
0.21
0.0
1.1
—
38.23
—
0
10
0
10
0.00
0.21
0.0
3.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
132.20
—
0
10
10
123
0.81
0.20
2.1
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
9
113
0.79
0.20
5.2
8.8
—
—
—
0
0
305
3007
1.08
0.20
5.0
5.1
5.85
5.99
mmol/l
1.46
276
2744
109
1138
0.94
0.19
3.0
3.5
112.42
43.75
mg/l
0.64
68
741
32
290
1.11
0.19
1.5
1.9
—
—
—
0
0
72
682
1.07
0.17
2.6
2.8
0.97
0.74
ug/l
0.76
51
438
47
440
1.08
0.15
3.0
2.6
152.22
108.31
ug/g
0.56
37
340
34
314
1.09
0.14
1.4
1.5
—
—
—
0
0
309
3122
0.94
0.14
5.2
6.0
2.57
2.64
mmol/l
0.84
285
2910
17
152
1.12
0.12
1.8
2.0
—
—
—
0
0
112
1151
0.96
0.11
3.5
4.2
9.70
6.78
mg/mmol
0.37
66
741
305
3075
0.95
0.10
4.8
5.3
4.42
4.53
mmol/l
1.10
279
2873
305
3061
0.98
0.03
4.7
5.2
1.37
1.44
mmol/l
2.21
278
2842
124
1247
0.99
0.01
3.1
3.5
7.44
7.80
mmol/l
0.37
100
1079
12
126
0.95
0.00
1.1
1.3
—
—
—
0
0
12
118
1.02
0.00
1.8
1.6
—
—
—
0
0
13
128
1.02
0.00
1.3
1.6
—
10.03
—
0
28
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
23.52
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
71.86
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
10.1
—
1.20
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
12.41
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
74.67
—
0
6
7
77
0.91
-0.00
3.7
1.7
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_BONE_CARTILAGE – Malignant neoplasm of bone and articular cartilage

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).