This is a non-core endpoint: only basic statistics are computed.
Malignant neoplasm of bone and articular cartilage of limbs
C3_BONE_CARTILAGE_LIMBS
bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
178 |
4. Check minimum number of eventsNone |
178 |
5. Include endpointsNone |
178 |
6. Filter based on genotype QC (FinnGen only) |
160 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of bone and articular cartilage of limbs
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of bone and articular cartilage
- Malignant neoplasm of bone and articular cartilage of limbs, including Hilmo
- Malignant neoplasm of bone and articular cartilage, including Hilmo
- Solid cancers
- Malignant neoplasm
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 160 | 69 | 91 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.04 |
| Median age at first event (years) | 36.81 | 38.13 | 35.81 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 165
- Matched controls
- 1650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
292.3
82.7
78
5
NF3AA
NOMESCO Finland
Femur X-ray examination
51.2
74.9
45
12
130
Kela drug reimbursment
Malignant tumour
+∞
71.1
63
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
57.8
52
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
53.0
48
*
N02AA05
ATC
oxycodone; systemic
10.0
44.3
66
103
NG4AA
NOMESCO Finland
Lower leg X-ray examination
18.8
43.0
37
25
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
40.3
37
*
GD1AD
NOMESCO Finland
Thorax CT examination
15.6
37.9
36
29
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
36.9
34
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
16.2
36.8
34
26
JN4BD
NOMESCO Finland
Extensive body CT
14.1
34.8
35
31
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
34.6
32
*
JN4AD
NOMESCO Finland
Body CT examination
12.4
34.3
38
39
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
33.5
31
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
33.5
31
*
L03AA02
ATC
filgrastim; parenteral
397.1
33.1
32
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
7.6
32.2
59
113
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
31.2
29
*
A04AA01
ATC
ondansetron; systemic, rectal
32.5
29.1
38
15
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
29.0
27
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
27.9
26
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
27.9
26
*
H02AB02
ATC
dexamethasone; systemic
90.7
27.8
30
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
9.4
27.5
37
49
B01AB10
ATC
tinzaparin; parenteral
9.0
27.1
38
53
WX306
NOMESCO Finland
Lumbar epidural anesthesy
10.4
25.4
31
36
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
24.6
23
*
L03AA13
ATC
pegfilgrastim; parenteral
278.8
24.3
24
*
A03FA01
ATC
metoclopramide; systemic, rectal
6.1
24.0
52
115
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
+∞
23.5
22
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.2
23.1
113
487
ZXE20
NOMESCO Finland
More than three and less than five hours
6.1
22.5
48
104
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.2
22.5
30
39
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
+∞
22.4
21
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
51.0
22.1
26
6
TPX10
NOMESCO Finland
Implantation of vascular injection port
30.3
21.3
28
11
Z51.5
ICD-10 Finland
Palliative care
18.6
20.8
32
21
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
20.8
69
217
B01AB05
ATC
enoxaparin; parenteral
4.6
20.6
75
253
WW500
NOMESCO Finland
Blood transfusion
24.5
19.4
27
13
WX402
NOMESCO Finland
General anaesthesia
4.8
18.7
56
161
R4110
NOMESCO Finland
Physiotherapy
4.2
18.2
75
273
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
18.0
17
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
18.0
17
*
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
200.7
17.9
18
*
A04AA02
ATC
granisetron; systemic, transdermal
200.7
17.9
18
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
17.0
16
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
25.1
16.0
22
10
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
15.9
15
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
15.9
15
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
176.0
15.8
16
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
42.6
15.8
19
5
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
88.2
14.8
16
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.0
14.6
36
87
ZXE30
NOMESCO Finland
More than five and less than seven hours
12.1
14.4
26
25
N03AX16
ATC
[U] pregabalin
3.8
14.3
58
204
XX3DW
NOMESCO Finland
Time consuming IT work
7.3
14.0
22
34
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
13.7
13
*
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
13.7
13
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
13.7
13
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
23.6
13.7
19
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.0
13.7
48
152
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.5
13.5
66
261
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
12.7
12
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
12.7
12
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.0
11.7
22
41
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
13.2
11.7
20
17
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.6
11
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
11.6
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
11.6
11
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
+∞
11.6
11
*
NB6AA
NOMESCO Finland
Humerus X-ray examination
13.2
11.2
19
16
ZXA05
NOMESCO Finland
Left side
3.2
10.8
58
239
ZX090
NOMESCO Finland
Other technic of radiotherapy
117.2
10.5
11
*
TPX15
NOMESCO Finland
Removal of vascular injection port
117.2
10.5
11
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
117.2
10.5
11
*
ZX120
NOMESCO Finland
Intravenous
4.8
10.5
26
62
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.5
10
*
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
10.5
10
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
+∞
10.5
10
*
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.5
10
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.5
10
*
9101
FHL
Bone biopsy
+∞
10.5
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
3.0
10.4
72
342
J01FF01
ATC
clindamycin; systemic
3.2
10.2
54
220
ZXE10
NOMESCO Finland
More than one and less than three hours
2.9
9.9
68
320
NF1AA
NOMESCO Finland
Hip X-ray examination
4.6
9.6
25
62
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
5.7
9.6
19
37
NG1AD
NOMESCO Finland
Knee CT examination
13.5
9.6
16
13
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
32.1
9.5
12
*
J04AB02
ATC
rifampicin; systemic
32.1
9.5
12
*
NF3AD
NOMESCO Finland
Femur CT
105.8
9.5
10
*
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
105.8
9.5
10
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
105.8
9.5
10
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
105.8
9.5
10
*
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
105.8
9.5
10
*
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
9.5
9
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
9.5
9
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
9.5
9
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
9.5
9
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
9.5
9
*
A04AD12
ATC
aprepitant; systemic
+∞
9.5
9
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
9.5
9
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
9.5
9
*
L71
ICPC
Malignant neoplasm musculoskeletal
+∞
9.5
9
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.2
9.1
20
43
TPH07
NOMESCO Finland
Cathetrisation of artery
3.9
9.0
29
85
WZC30
NOMESCO Finland
Teaching
3.6
9.0
33
106
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
7.7
8.9
20
29
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
12.6
8.8
15
13
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
13.8
8.5
14
11
NK6AN
NOMESCO Finland
Total body bone isotope imaging
+∞
8.4
8
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
8.4
8
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
+∞
8.4
8
*
Z89.6
ICD-10 Finland
Acquired absence of leg above knee
+∞
8.4
8
*
159
Kela drug reimbursment
Pazopanib
+∞
8.4
8
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.4
8
*
NFA20
NOMESCO Finland
Exploration of hip joint or femur
+∞
8.4
8
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.7
8.2
20
47
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
8.1
28
86
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.5
8.1
21
52
N02AX02
ATC
tramadol; systemic, rectal
2.6
8.1
80
443
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
14.0
8.0
13
10
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
8.0
73
388
D70.82
ICD-10 Finland
Drug-induced neutropenia
47.3
7.8
9
*
NGQ20
NOMESCO Finland
Amputation of lower leg
47.3
7.8
9
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
19.5
7.7
11
6
NFQ20
NOMESCO Finland
Amputation of femur
26.4
7.7
10
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
7.6
58
281
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.1
7.6
22
59
ZXE40
NOMESCO Finland
More than seven and less than nine hours
14.3
7.5
12
9
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
9.0
7.5
15
18
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
83.7
7.5
8
*
XW000
NOMESCO Finland
Bone marrow biopsy
11.6
7.4
13
12
J01MA12
ATC
levofloxacin; systemic
3.0
7.4
39
156
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
7.3
7
*
C40.0
ICD-10 Finland
Malignant neoplasm: Scapula and long bones of upper limb
+∞
7.3
7
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
7.3
7
*
C40.10
ICD-10 Finland
Malignant tumor of the upper limb's short bones without histology
+∞
7.3
7
*
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
7.3
7
*
JN4CD
NOMESCO Finland
Very extensive body CT
16.7
7.3
11
7
ZXE00
NOMESCO Finland
One hour or less
2.5
7.2
74
411
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
31.5
7.2
9
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
21.1
7.2
10
5
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.7
7.0
24
73
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.9
7.0
14
17
R4120
NOMESCO Finland
Occupational therapy
4.3
6.9
19
49
N02BE01
ATC
paracetamol; systemic, rectal
4.5
6.9
153
1220
R50.9
ICD-10 Finland
Fever, unspecified
2.8
6.8
39
162
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.2
6.7
19
50
L28
ICPC
Limited function/disability (L)
2.7
6.7
43
190
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
72.5
6.5
7
*
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
72.5
6.5
7
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.5
6.5
24
77
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
6.5
29
105
ZXD05
NOMESCO Finland
Urgent procedure
2.4
6.4
58
303
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.3
6.3
17
43
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
18.9
6.3
9
5
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
6.2
6.3
16
28
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
27.8
6.3
8
*
C40.12
ICD-10 Finland
Chondrosarcoma of the short bones of the upper extremity
+∞
6.3
6
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
NGB99
NOMESCO Finland
Other primary prosthetic replacement of knee joint, other or unspecified
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
6.3
6
*
343
Kela drug reimbursment
Pazopanib
+∞
6.3
6
*
WX1DG
NOMESCO Finland
Very extensive total body MRI with high intensity magnet
+∞
6.3
6
*
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
+∞
6.3
6
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
6.3
6
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
6.3
6
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
6.3
6
*
C40.23
ICD-10 Finland
Ewing's sarcoma in the long bones of the lower extremity
+∞
6.3
6
*
NK6AT
NOMESCO Finland
Bone biopsy with ultrasound guidance
+∞
6.3
6
*
NGR40
NOMESCO Finland
Extensive excision of tumor of knee or lower leg with repair
+∞
6.3
6
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.7
6.2
21
63
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
6.2
38
164
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.4
6.0
23
75
WX002
NOMESCO Finland
Sedation and analgesia
2.7
6.0
38
166
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
119
5.76
22.04
8.5
2.5
252.86
226.67
u/l
0.90
51
114
82
284
4.75
22.01
7.0
2.2
—
—
—
0
0
114
561
4.34
17.89
21.3
8.9
1.21
1.21
mmol/l
0.23
105
515
107
512
4.10
17.29
11.3
5.0
34.46
36.35
g/l
2.72
101
485
16
0
+∞
16.96
31.9
0.0
0.37
—
umol/l
—
16
0
121
637
4.37
16.88
22.7
9.0
1.20
1.21
mmol/l
0.55
105
568
109
553
3.86
15.60
6.0
2.6
—
—
estimate
—
0
0
50
158
4.11
14.35
2.2
1.7
—
—
—
0
0
48
150
4.10
13.96
2.4
1.8
—
—
—
0
0
29
60
5.65
13.92
2.3
1.6
3.38
2.81
ug/l
0.17
21
45
126
737
4.00
13.84
28.5
7.1
3.91
4.21
e9/l
0.48
113
617
56
206
3.60
12.74
2.6
1.8
—
—
—
0
0
23
25
10.50
11.96
1.8
1.4
—
—
—
0
0
45
149
3.78
11.90
13.3
12.3
5.18
5.12
kpa
0.19
45
144
44
144
3.80
11.83
13.5
12.6
0.22
0.94
mmol/l
0.83
39
128
144
980
4.69
11.43
17.3
5.9
96.40
82.04
u/l
1.09
139
912
20
41
5.41
9.59
2.7
3.8
—
—
—
0
0
46
181
3.14
9.08
27.3
9.4
104.59
104.80
mmol/l
0.09
46
181
21
48
4.87
8.91
29.6
12.9
1.16
1.57
mg/l
2.02
21
42
21
33
7.13
8.83
1.5
1.3
—
—
—
0
0
84
463
2.66
8.73
4.4
3.7
—
—
—
0
0
13
9
15.54
8.35
1.2
1.1
—
—
—
0
0
18
40
4.93
7.86
8.2
3.3
3.93
3.65
g/l
0.31
18
40
19
31
6.78
7.82
1.5
1.2
—
—
—
0
0
15
17
9.58
7.73
1.3
1.2
—
—
—
0
0
17
24
7.76
7.71
5.2
1.1
3.28
1.42
ratio
0.37
11
15
24
69
3.90
7.60
2.5
1.6
—
—
—
0
0
63
332
2.45
6.85
3.6
2.6
320.95
349.64
umol/l
1.12
58
302
68
382
2.33
6.30
3.5
3.5
0.23
0.27
e6/l
0.21
49
273
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
34
5.45
6.07
15.8
3.3
0.31
0.29
iu/ml
—
10
17
16
30
5.79
6.02
1.6
1.4
—
—
—
0
0
12
15
8.53
5.95
1.4
1.3
—
—
—
0
0
16
31
5.60
5.88
1.3
1.2
—
—
—
0
0
44
214
2.44
5.56
3.4
3.1
12.02
14.03
umol/l
0.86
44
199
23
80
3.18
5.45
2.0
1.6
—
—
—
0
0
131
1003
2.49
5.42
6.3
4.5
14.74
10.24
mm/h
2.37
124
926
26
100
2.90
5.19
4.5
3.2
—
—
—
0
0
13
24
5.78
5.03
1.9
2.2
—
—
—
0
0
9
11
8.58
4.62
1.1
1.2
—
—
—
0
0
13
27
5.13
4.61
1.2
1.1
—
—
—
0
0
27
113
2.66
4.60
3.0
3.4
0.19
0.22
g/l
0.86
27
103
14
32
4.68
4.56
1.6
1.7
—
—
—
0
0
31
141
2.48
4.47
11.8
6.2
—
—
—
0
0
97
690
1.98
4.41
4.8
3.7
0.00
0.00
estimate
-0.00
16
150
37
185
2.29
4.32
3.2
3.1
22.79
24.55
%
0.27
37
172
9
13
7.25
4.22
1.1
1.2
—
—
—
0
0
10
17
6.19
4.20
1.1
1.1
—
—
—
0
0
65
412
1.95
4.05
4.8
3.3
1585.39
1095.41
ng/l
0.39
58
344
11
23
5.04
3.95
1.2
1.1
—
—
—
0
0
96
698
1.90
3.91
4.9
3.8
0.00
0.03
estimate
0.50
16
139
94
679
1.89
3.90
4.8
3.7
0.00
0.00
estimate
-0.00
16
147
7
8
9.07
3.81
8.6
3.1
10.00
15.25
%
—
7
8
7
8
9.07
3.81
8.6
3.1
—
—
—
0
0
21
87
2.62
3.64
2.5
1.9
84.90
71.12
ml/min/173m2
—
10
26
137
1138
2.20
3.63
43.6
16.7
14.25
13.42
%
7.36
137
1123
146
1245
2.50
3.62
28.0
11.9
87.18
83.30
ml/min/173m2
0.92
136
1123
6
6
10.31
3.52
1.2
1.0
—
—
—
0
0
8
14
5.94
3.38
1.0
1.1
—
—
—
0
0
41
245
1.90
2.94
3.0
3.1
1.34
0.97
e6/l
0.36
20
128
153
1362
2.70
2.93
38.3
13.2
30.68
22.91
mg/l
1.65
141
1046
7
13
5.57
2.90
1.3
1.2
—
—
—
0
0
7
14
5.17
2.76
2.9
2.0
310.71
958.71
mg
—
7
14
9
24
3.90
2.71
1.7
1.3
0.20
0.60
nmol/l
—
9
18
8
19
4.37
2.71
1.5
1.0
—
—
—
0
0
21
102
2.21
2.61
4.6
5.7
78.32
77.95
ng/l
0.01
21
91
12
44
2.86
2.61
5.8
2.8
218.25
177.50
%
0.92
12
44
44
279
1.79
2.59
3.8
3.9
33.30
378.39
ng/l
1.71
37
222
47
304
1.76
2.59
3.7
1.8
2.03
1.22
mg/l
0.91
40
234
24
124
2.09
2.56
9.3
5.9
5.15
5.02
kpa
0.64
24
119
6
11
5.61
2.56
1.2
1.3
—
—
—
0
0
5
7
7.32
2.56
3.6
3.0
821.80
704.29
u/ml
—
5
7
8
21
3.95
2.49
1.3
1.4
—
—
—
0
0
10
32
3.26
2.48
1.7
1.4
—
—
—
0
0
5
9
5.69
2.23
1.6
1.0
—
—
—
0
0
5
9
5.69
2.23
1.6
1.0
—
—
—
0
0
5
9
5.69
2.23
1.6
1.0
—
—
—
0
0
121
1028
1.66
2.18
5.2
4.0
15.08
14.69
pmol/l
0.86
112
940
52
365
1.62
2.08
5.9
3.8
0.00
0.00
estimate
-0.00
16
137
70
528
1.57
2.07
5.0
3.5
0.00
0.00
estimate
-0.00
15
120
12
51
2.46
2.00
2.7
2.2
8.43
18.10
iu/l
—
6
43
8
27
3.06
1.96
1.6
1.2
—
—
—
0
0
8
27
3.06
1.96
1.6
1.2
—
—
—
0
0
5
11
4.65
1.95
1.4
1.2
—
—
—
0
0
14
66
2.23
1.88
1.5
1.6
—
—
—
0
0
67
511
1.52
1.84
4.8
3.8
22.06
50.57
ng/l
1.97
55
351
5
12
4.26
1.83
1.4
1.2
—
—
—
0
0
5
12
4.26
1.83
1.4
1.2
—
—
—
0
0
6
18
3.42
1.76
2.8
1.7
3.21
6.97
u/ml
—
6
18
48
343
1.56
1.75
2.7
2.6
2.92
2.59
mg/l
0.50
40
294
34
223
1.66
1.75
3.9
3.3
2.70
3.10
e6/l
0.10
12
107
5
13
3.93
1.72
1.4
1.2
—
—
—
0
0
5
13
3.93
1.72
1.4
1.2
—
—
—
0
0
5
13
3.93
1.72
1.4
1.2
—
—
—
0
0
15
79
1.99
1.55
45.5
6.3
0.70
0.62
%
0.51
15
79
15
79
1.99
1.55
45.5
6.3
1.35
1.24
%
0.29
15
79
7
27
2.66
1.53
1.6
1.1
—
—
—
0
0
19
111
1.80
1.46
3.2
2.7
1.52
0.18
e6/l
0.91
19
104
138
1259
1.59
1.38
5.9
5.0
2.21
1.89
mu/l
1.59
128
1156
75
616
1.40
1.31
2.8
2.9
79.94
76.20
nmol/l
0.54
66
543
26
172
1.61
1.31
43.3
6.0
6.08
5.69
kpa
2.12
26
167
50
385
1.43
1.24
1.7
1.6
21.17
19.71
nmol/l
0.33
43
325
8
39
2.10
1.17
1.0
1.3
—
—
—
0
0
44
335
1.43
1.16
5.1
3.4
1.02
1.02
kg/l
0.22
31
212
59
475
1.38
1.13
4.4
4.2
2.05
2.01
ug/l
0.05
54
422
14
227
0.58
1.13
1.1
1.4
1.12
14.04
u/ml
—
5
90
5
106
0.46
1.05
1.8
1.7
3.66
3.53
mmol/l
—
5
77
14
222
0.60
1.04
2.0
2.4
—
—
—
0
0
22
149
1.55
1.02
44.7
6.2
4.15
4.84
kpa
1.29
22
143
8
42
1.95
0.90
3.0
1.8
—
—
—
0
0
13
201
0.62
0.88
2.1
2.3
—
—
—
0
0
8
44
1.86
0.87
3.0
1.8
—
—
—
0
0
21
148
1.48
0.83
4.2
2.0
348.48
378.54
nmol/l
0.36
21
138
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
0
28
0.00
0.77
0.0
1.2
—
1.44
—
0
6
0
20
0.00
0.61
0.0
1.8
—
—
—
0
0
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
8.56
—
0
17
7
107
0.64
0.50
2.3
2.1
—
—
—
0
0
10
138
0.71
0.42
2.2
2.0
3.67
3.63
ratio
—
10
109
20
247
0.78
0.42
1.6
1.3
117.93
30.52
iu/ml
—
9
79
5
33
1.53
0.41
1.4
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
99
927
1.17
0.41
4.1
3.6
51.05
45.07
u/l
0.47
94
881
0
17
0.00
0.41
0.0
1.2
—
170.13
—
0
17
0
17
0.00
0.41
0.0
1.2
—
13.19
—
0
7
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
51
568
0.85
0.39
2.0
2.0
1.28
1.33
mmol/l
0.14
43
497
66
605
1.15
0.35
2.0
2.0
95.15
94.23
pmol/l
0.04
31
301
6
89
0.66
0.34
2.3
2.1
—
—
—
0
0
124
1192
1.16
0.32
50.9
17.2
331.23
333.73
g/l
2.05
124
1185
34
382
0.86
0.28
1.1
1.6
1.24
2.24
u/ml
—
5
103
44
398
1.14
0.28
4.2
3.1
0.00
0.00
estimate
-0.00
13
116
5
37
1.36
0.24
1.0
1.5
1.13
0.75
nmol/l
—
5
32
5
37
1.36
0.24
1.0
1.1
—
2.98
—
0
5
20
173
1.18
0.22
5.2
4.5
29.38
31.26
%
0.32
13
114
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
49
1.23
0.20
1.7
1.6
0.16
0.21
g/l
—
6
49
94
904
1.09
0.19
4.1
3.3
—
—
—
0
0
33
302
1.12
0.18
1.3
1.7
—
—
—
0
0
120
1230
0.91
0.17
6.7
6.5
39.19
39.49
mmol/mol
0.12
108
1163
40
375
1.09
0.14
4.0
3.7
23.41
24.43
%
0.17
22
177
9
108
0.82
0.13
1.3
1.4
—
—
—
0
0
20
219
0.90
0.12
1.5
1.8
1351.54
1103.65
nmol/l
0.55
13
177
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
5
46
1.09
0.09
1.2
1.3
—
13.56
—
0
8
125
1235
1.05
0.06
4.7
4.2
1.24
1.28
mmol/l
0.30
111
1145
18
168
1.08
0.06
1.3
1.4
—
—
—
0
0
48
466
1.04
0.05
3.8
4.1
4.71
7.01
mg/mmol
0.49
29
313
26
251
1.04
0.03
1.7
1.8
397.95
433.88
pmol/l
0.45
21
219
131
1318
0.97
0.02
5.4
5.0
4.45
4.53
mmol/l
0.39
119
1240
133
1335
0.98
0.00
5.7
5.7
2.60
2.66
mmol/l
0.35
121
1252
129
1292
0.99
0.00
5.3
4.8
5.78
5.92
mmol/l
0.75
118
1181
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
17.55
—
0
8
5
54
0.92
0.00
1.4
1.3
—
291.47
—
0
30
0
9
0.00
-0.00
0.0
1.1
—
8.22
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
73.83
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.34
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
11.43
—
0
5
0
5
0.00
-0.00
0.0
9.2
—
5.98
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
188.33
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
395.33
—
0
6
5
49
1.02
-0.00
1.8
1.7
1.06
1.14
g/l
—
5
49
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
131
1310
1.00
-0.00
5.3
4.9
1.41
1.42
mmol/l
0.08
119
1223
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
27
270
1.00
-0.00
2.4
2.8
0.94
0.82
ug/l
0.26
20
168
0
6
0.00
-0.00
0.0
1.0
—
20.08
—
0
6
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_BONE_CARTILAGE_LIMBS – Malignant neoplasm of bone and articular cartilage of limbs
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).