This is a non-core endpoint: only basic statistics are computed.
Osteosarcoma
C3_OSTEOSARCOMA
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
91 |
4. Check minimum number of eventsNone |
91 |
5. Include endpointsNone |
91 |
6. Filter based on genotype QC (FinnGen only) |
83 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Osteosarcoma
based on the number of shared cases.
Similar with more cases:
- Osteosarcoma, including Hilmo
- Malignant neoplasm of bone and articular cartilage
- Malignant neoplasm of bone and articular cartilage, including Hilmo
- Solid cancers
- Malignant neoplasm
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 83 | 35 | 48 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 23.33 | 17.39 | 27.66 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 85
- Matched controls
- 850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
63.8
53
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
62.3
52
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
51.3
44
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
270.3
44.6
42
*
N02AA05
ATC
oxycodone; systemic
17.1
37.7
41
44
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
25.3
23
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
87.0
23.3
25
*
NF3AA
NOMESCO Finland
Femur X-ray examination
82.2
22.2
24
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
49.6
21.3
25
7
L03AA02
ATC
filgrastim; parenteral
257.5
20.5
20
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.1
20.3
32
53
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
19.5
18
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
8.7
18.2
29
48
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
17.3
16
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
17.3
16
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.4
17.2
33
67
A04AA01
ATC
ondansetron; systemic, rectal
39.1
17.1
21
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.9
16.9
59
210
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.7
16.7
39
96
B01AB05
ATC
enoxaparin; parenteral
6.4
16.3
42
113
ZXE20
NOMESCO Finland
More than three and less than five hours
7.6
16.3
29
54
NG4AA
NOMESCO Finland
Lower leg X-ray examination
23.7
16.3
23
13
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
16.1
15
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
16.1
15
*
GD1AD
NOMESCO Finland
Thorax CT examination
18.1
16.0
25
19
N03AX16
ATC
[U] pregabalin
6.2
15.3
38
98
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
15.0
14
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
25.6
14.6
20
10
ZXA05
NOMESCO Finland
Left side
6.1
14.5
36
92
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
64.8
14.4
16
*
H02AB02
ATC
dexamethasone; systemic
64.8
14.4
16
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
13.9
13
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
13.9
13
*
L03AA13
ATC
pegfilgrastim; parenteral
165.3
13.9
14
*
WX402
NOMESCO Finland
General anaesthesia
5.7
13.4
35
93
TPH07
NOMESCO Finland
Cathetrisation of artery
7.9
13.2
21
34
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
7.9
13.2
21
34
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
38.8
13.1
16
5
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
82.6
13.0
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
5.2
12.8
41
129
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
+∞
12.8
12
*
JN4BD
NOMESCO Finland
Extensive body CT
15.9
12.4
20
16
R4110
NOMESCO Finland
Physiotherapy
4.9
11.9
41
136
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.9
11.8
21
21
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
11.7
11
*
WW500
NOMESCO Finland
Blood transfusion
29.8
11.6
15
6
ZXE10
NOMESCO Finland
More than one and less than three hours
4.7
11.6
45
163
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
10.6
10
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
10.6
10
*
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
10.6
10
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
10.6
10
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
10.6
10
*
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.6
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.3
10.3
49
203
JN4AD
NOMESCO Finland
Body CT examination
11.7
9.9
18
19
TPX15
NOMESCO Finland
Removal of vascular injection port
112.0
9.6
10
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.2
9.6
19
38
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
9.5
9
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
9.5
9
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
12.8
9.3
16
15
Z51.5
ICD-10 Finland
Palliative care
21.6
9.3
13
7
ZXA00
NOMESCO Finland
Right side
4.4
9.1
31
99
ZXE00
NOMESCO Finland
One hour or less
3.9
8.7
49
221
N02BF02
ATC
pregabalin; oral
11.3
8.7
16
17
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
14.9
8.7
14
11
J04AB02
ATC
rifampicin; systemic
99.5
8.6
9
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
16.8
8.5
13
9
Z89.6
ICD-10 Finland
Acquired absence of leg above knee
+∞
8.5
8
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
15.1
8.2
13
10
WZC30
NOMESCO Finland
Teaching
4.9
8.2
21
53
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
5.4
8.1
18
40
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.1
8.0
29
96
J01MA12
ATC
levofloxacin; systemic
4.5
7.8
23
65
WX306
NOMESCO Finland
Lumbar epidural anesthesy
7.6
7.8
18
29
N02AX02
ATC
tramadol; systemic, rectal
3.6
7.7
45
204
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
7.4
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.4
7
*
9101
FHL
Bone biopsy
+∞
7.4
7
*
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
7.4
7
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
+∞
7.4
7
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.9
7.2
18
44
ZXD10
NOMESCO Finland
Scheduled procedure
3.4
7.2
43
196
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
9.6
7.2
14
17
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
43.7
6.9
8
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
24.8
6.8
9
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.8
6.7
17
42
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.8
6.7
17
42
A04AA02
ATC
granisetron; systemic, transdermal
75.3
6.5
7
*
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
75.3
6.5
7
*
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
75.3
6.5
7
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
75.3
6.5
7
*
NB6AA
NOMESCO Finland
Humerus X-ray examination
19.9
6.4
9
5
J01FF01
ATC
clindamycin; systemic
3.4
6.4
31
123
ZZA00
NOMESCO Finland
Split skin graft
29.1
6.3
8
*
JN4CD
NOMESCO Finland
Very extensive body CT
29.1
6.3
8
*
GDA20
NOMESCO Finland
Excision of lesion of lung
+∞
6.3
6
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
6.3
6
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
+∞
6.3
6
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
+∞
6.3
6
*
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
9.1
6.1
12
15
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
16.5
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
0
+∞
18.38
32.5
0.0
0.37
—
umol/l
—
17
0
33
88
5.50
12.50
2.5
1.6
—
—
—
0
0
42
139
5.00
12.26
10.1
2.2
—
—
—
0
0
63
290
5.53
12.02
36.9
9.6
1.20
1.21
mmol/l
0.83
57
265
28
70
5.47
11.30
42.5
12.7
105.36
105.09
mmol/l
0.11
28
70
27
66
5.53
11.16
2.5
1.4
—
—
—
0
0
26
62
5.60
11.03
2.7
1.5
—
—
—
0
0
61
308
4.47
9.45
25.2
4.1
8.33
12.18
umol/l
3.32
61
295
20
29
8.67
9.24
25.5
14.9
24.17
23.98
mmol/l
0.08
20
29
21
33
8.09
9.23
25.6
15.2
0.85
0.64
%
1.13
21
33
21
33
8.09
9.23
25.5
15.2
1.19
1.43
%
0.73
21
33
55
273
3.87
8.40
7.6
2.5
—
—
estimate
—
0
0
16
21
9.11
7.82
10.1
3.9
3.66
4.03
g/l
0.32
16
21
12
11
12.46
7.05
2.4
1.8
—
—
—
0
0
64
381
3.75
6.82
38.9
8.6
3.82
4.02
e9/l
0.30
56
319
20
58
4.20
6.48
3.8
3.8
0.20
0.23
g/l
0.59
20
52
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
17
8.80
6.40
19.6
4.5
0.23
0.29
iu/ml
—
7
11
15
26
6.76
6.18
2.2
1.3
—
—
—
0
0
44
222
3.04
5.95
4.7
4.3
—
—
—
0
0
12
16
8.53
5.87
1.8
1.6
—
—
—
0
0
20
63
3.84
5.76
70.4
19.9
25.36
24.71
mmol/l
0.60
20
63
8
5
17.43
5.52
1.4
1.2
—
—
—
0
0
26
104
3.16
5.16
5.3
3.1
13.98
14.71
umol/l
0.14
26
97
11
16
7.71
5.14
1.9
1.5
—
—
—
0
0
11
17
7.25
4.96
1.8
1.3
—
—
—
0
0
9
10
9.90
4.91
1.6
1.3
—
—
—
0
0
13
27
5.49
4.73
6.8
3.1
220.23
182.96
%
0.88
13
27
36
184
2.66
4.49
3.3
4.1
0.28
0.19
e6/l
0.30
26
125
15
39
4.44
4.47
2.8
1.9
98.11
79.93
ml/min/173m2
—
9
14
7
8
9.40
3.85
1.1
1.3
—
—
—
0
0
20
81
2.92
3.81
7.5
3.9
4.08
9.34
umol/l
0.74
20
72
14
46
3.45
3.73
6.7
7.7
68.84
68.37
ng/l
0.01
14
41
14
46
3.45
3.73
5.4
2.9
—
—
—
0
0
12
34
3.94
3.36
1.8
1.6
—
—
—
0
0
7
11
6.82
3.25
1.1
1.2
—
—
—
0
0
9
20
4.90
3.21
2.1
3.2
—
—
—
0
0
8
16
5.40
3.13
1.5
1.2
—
—
—
0
0
6
8
7.96
3.10
1.8
1.6
—
—
—
0
0
5
7
7.49
2.58
1.2
1.0
—
—
—
0
0
8
23
3.73
2.33
1.9
1.6
—
—
—
0
0
13
54
2.66
2.33
15.9
5.4
—
—
—
0
0
6
13
4.88
2.31
1.3
1.2
—
—
—
0
0
6
13
4.88
2.31
1.5
2.0
—
—
—
0
0
8
24
3.57
2.24
79.4
15.0
0.55
0.60
%
—
8
24
8
24
3.57
2.24
79.4
15.0
1.29
1.23
%
—
8
24
6
14
4.52
2.19
2.7
2.6
—
—
—
0
0
7
20
3.72
2.10
2.0
1.9
—
—
—
0
0
5
10
5.23
2.10
1.8
1.1
—
—
—
0
0
33
213
1.90
2.05
3.8
3.1
13.18
50.51
ng/l
1.49
25
132
5
11
4.75
1.97
1.2
1.1
—
—
—
0
0
79
703
2.75
1.88
47.7
11.5
31.60
23.50
mg/l
1.04
74
523
6
20
3.15
1.61
1.0
1.1
—
—
—
0
0
6
20
3.15
1.61
2.2
1.8
—
—
—
0
0
6
20
3.15
1.61
1.0
1.1
—
—
—
0
0
11
53
2.24
1.46
78.0
11.7
24.76
23.66
mmol/l
0.65
11
53
44
344
1.58
1.24
6.3
3.8
0.00
0.00
estimate
—
8
71
5
19
2.73
1.23
1.0
1.0
—
—
—
0
0
5
20
2.59
1.17
1.0
1.3
—
—
—
0
0
19
123
1.70
1.12
2.9
3.4
1.16
0.75
e6/l
—
7
65
42
338
1.48
0.97
6.5
3.8
0.00
0.00
estimate
—
8
68
25
182
1.53
0.92
4.2
2.2
765.12
240.98
u/l
0.62
25
175
6
31
2.00
0.86
1.3
1.4
—
—
—
0
0
42
348
1.41
0.79
6.3
3.8
0.00
0.00
estimate
—
8
64
60
531
1.44
0.76
5.3
3.4
56.95
40.71
u/l
1.25
60
511
24
183
1.43
0.70
3.1
4.0
17.25
6.65
mg/mmol
0.40
15
132
30
245
1.35
0.58
2.0
1.8
100.03
93.08
pmol/l
0.22
12
134
25
200
1.35
0.55
1.4
1.8
—
—
—
0
0
7
45
1.60
0.50
1.0
1.2
—
—
—
0
0
12
160
0.71
0.45
1.8
2.4
—
—
—
0
0
22
178
1.32
0.45
8.0
3.6
0.00
0.00
estimate
—
8
69
11
147
0.71
0.41
1.8
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
53.92
—
0
19
0
19
0.00
0.39
0.0
2.3
—
—
—
0
0
29
255
1.21
0.29
7.3
3.5
0.00
0.00
estimate
—
8
59
6
81
0.72
0.25
1.3
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
206.38
—
0
10
0
12
0.00
0.21
0.0
1.4
—
8.53
—
0
12
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
21
191
1.13
0.13
6.5
2.8
0.00
0.00
estimate
—
7
60
66
677
0.89
0.11
5.3
4.3
4.68
4.61
mmol/l
0.25
61
646
5
47
1.07
0.09
1.0
1.4
—
—
—
0
0
55
564
0.93
0.07
3.9
3.6
—
—
—
0
0
9
104
0.85
0.06
1.7
1.6
—
—
—
0
0
13
127
1.03
0.00
1.9
2.9
0.56
0.79
ug/l
—
8
81
17
165
1.04
0.00
2.1
3.6
26.62
23.83
%
—
9
80
6
67
0.89
0.00
1.3
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
8.00
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
7.01
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
2.6
2.1
3.18
8.22
ug/l
—
5
44
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_OSTEOSARCOMA – Osteosarcoma
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).