Postinfectious hypothyroidism

E4_HYTHYPOSTINF

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E03.3
  • Hospital discharge: ICD-9 2448A
  • Cause of death: ICD-10 E03.3
  • Cause of death: ICD-9 2448A

2 out of 7 registries used, show all original rules.

233

4. Check minimum number of events

None

233

5. Include endpoints

None

233

6. Filter based on genotype QC (FinnGen only)

200

Control definitions (FinnGen only)

Control exclude
E4_THYROID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E03
Name in latin
Hypothyreosis postinfectiosa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2062 1681 349
Only index persons 1434 1198 236
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.01
Only index persons 0.04 0.04 0.01
Median age at first event (years)
Whole population 55.61 56.08 52.28
Only index persons 48.62 49.33 45.03

-FinnGen-

Key figures

All Female Male
Number of individuals 200 165 35
Unadjusted period prevalence (%) 0.05 0.06 0.02
Median age at first event (years) 41.77 40.41 48.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
208
Matched controls
2080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H03AA01
ATC
levothyroxine sodium; systemic
2048.7
245.8
201
28
104
Kela drug reimbursment
Thyroid insufficiency
1923.6
185.7
153
*
2448A
ICD-9 Finland
Acquired hypothyroidism, Other specified acquired hypothyroidism[HYPOTHYREOSIS POST THYREOIDITIDEM]
+∞
171.5
140
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
577.5
157.2
138
7
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
+∞
80.6
72
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
50.0
46
*
A10AA02, ,
ATC
18.2
45.4
39
26
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
17.7
43.6
38
26
E03
ICD-10 Finland
Other hypothyroidism
502.3
42.8
41
*
E03.89
ICD-10 Finland
Other specified hypothyroidism
487.0
41.7
40
*
A10AB01
ATC
insulin (human); parenteral
15.9
40.2
37
28
A10AA01, ,
ATC
18.3
40.0
34
22
A10AB04
ATC
insulin lispro; parenteral
16.7
38.3
34
24
T89
ICPC
Diabetes insulin dependent
13.0
35.7
37
34
A10AC01
ATC
insulin (human); parenteral
7.8
31.2
50
81
T86
ICPC
Hypothyroidism/myxoedema
167.5
28.4
29
*
A10AB05
ATC
insulin aspart; parenteral
7.3
26.9
45
76
A10AE04
ATC
insulin glargine; parenteral
6.2
25.0
50
101
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
25.9
23.9
33
15
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
23.1
21.1
30
15
A10AE05
ATC
insulin detemir; parenteral
7.9
21.0
31
45
H04AA01
ATC
glucagon; nasal, parenteral
31.3
19.2
25
9
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
18.0
17
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
69.3
17.0
19
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
15.6
15.5
25
18
103
Kela drug reimbursment
Diabetes, insulin-treated
3.3
14.9
83
351
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.2
13.9
76
315
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
13.7
13
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
149.3
13.6
14
*
XCK10
NOMESCO Finland
Photography of fundus of eye
4.5
13.5
37
96
A10AE06
ATC
insulin degludec; parenteral
11.1
12.9
24
24
A10AD01
ATC
insulin (human); parenteral
14.6
12.2
20
15
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
10.2
11.8
23
25
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.5
10.7
42
140
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
24.9
10.4
14
6
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
42.3
10.1
12
*
K29.4
ICD-10 Finland
Chronic atrophic gastritis
12.2
9.8
17
15
H3603, E103,
ICD-10 Finland
57.8
9.7
11
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
57.8
9.7
11
*
SPAT1262
SPAT
Handing over of treatment supplies
3.0
9.3
48
188
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
38.5
9.1
11
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
8.7
117
727
J01FF01
ATC
clindamycin; systemic
2.5
8.6
69
340
B03BA03
ATC
hydroxocobalamin; parenteral
4.3
8.4
23
59
A12AA04
ATC
calcium carbonate; oral
23.1
8.1
11
5
A11CC03
ATC
alfacalcidol; systemic
11.4
7.9
14
13
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
7.8
53
239
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
7.6
77
418
24409
ICD-8 Finland
Myxoedema, (hypothyreosis) NUD
82.9
7.5
8
*
4019X
ICD-9 Finland
Essential hypertension, Unspecified
7.3
7.5
17
25
A10AA03, ,
ATC
16.5
7.3
11
7
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
12.6
7.2
12
10
A12BA01
ATC
potassium chloride; oral
4.4
7.0
18
44
107
Kela drug reimbursment
Pernicious anaemia
9.8
6.9
13
14
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
9.8
6.9
13
14
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
41.4
6.8
8
*
N06AA09
ATC
amitriptyline; systemic
3.0
6.7
31
113
H02AB04
ATC
methylprednisolone; systemic
2.6
6.6
42
182
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
10.5
6.6
12
12
T90
ICPC
Diabetes non-insulin dependent
2.3
6.5
59
302
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
72.0
6.5
7
*
C03DA01
ATC
spironolactone; oral
2.8
6.4
36
147
SPAT1263
SPAT
Sampling
2.1
6.3
96
604
E03.1
ICD-10 Finland
Congenital hypothyroidism without goitre
+∞
6.3
6
*
H03BB01
ATC
carbimazole; oral
27.6
6.3
8
*
CKC12
NOMESCO Finland
Photocoagulation of retina
4.4
6.2
16
39
OAB50, ,
SPAT
3.4
6.1
23
74
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.2
6.1
63
340

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
68
6.40
20.13
2.8
1.5
3.76
4.29
pmol/l
2.35
32
59
185
1372
4.15
10.68
11.7
2.8
16.55
14.54
pmol/l
14.29
176
1260
55
238
2.78
8.88
2.1
2.1
—
—
—
0
0
131
853
2.45
8.78
9.0
5.9
57.02
57.76
%
0.31
123
817
131
871
2.36
8.12
9.1
5.8
27.81
27.94
%
0.05
123
830
129
857
2.33
7.94
9.2
5.9
9.20
8.55
%
1.92
121
812
101
613
2.26
7.63
3.2
3.1
—
—
—
0
0
128
857
2.28
7.60
8.8
5.8
2.95
2.71
%
0.59
118
808
136
938
2.30
7.46
8.9
6.0
1.81
1.83
e9/l
0.08
125
840
127
853
2.26
7.41
9.3
5.9
0.71
0.69
%
0.17
117
801
22
61
3.91
7.24
3.0
4.4
—
—
—
0
0
92
559
2.16
6.72
8.3
5.6
—
—
—
0
0
132
922
2.18
6.71
8.7
6.0
0.59
0.56
e9/l
0.86
118
806
43
192
2.56
6.38
2.3
1.5
—
—
—
0
0
131
927
2.12
6.25
8.8
6.0
0.04
0.04
e9/l
0.46
115
808
134
962
2.10
6.08
8.9
6.2
0.19
0.18
e9/l
0.71
122
856
91
573
2.05
5.86
7.6
3.8
15.04
5.36
mg/mmol
1.02
60
339
55
286
2.25
5.80
1.7
1.7
1362.24
1309.06
nmol/l
0.08
50
219
126
900
2.01
5.61
11.8
5.8
1.21
1.22
mmol/l
1.00
110
786
78
472
2.04
5.54
4.3
3.8
—
—
—
0
0
12
17
7.42
5.52
1.6
1.2
23.45
18.20
ng/l
0.48
12
17
88
560
1.99
5.40
6.4
3.2
68.78
27.47
mg/l
1.09
60
339
53
282
2.18
5.24
1.6
1.4
366.67
516.00
titre
0.27
12
60
114
801
1.94
5.17
10.2
5.1
1.21
1.22
mmol/l
0.87
105
746
137
1033
1.96
4.93
10.2
9.8
4.23
4.18
e9/l
0.09
127
910
89
588
1.90
4.76
6.3
3.1
6.03
6.93
mmol/l
1.52
74
494
64
379
1.99
4.72
2.1
1.8
1817.91
460.22
pmol/l
0.50
56
322
139
1063
1.93
4.68
7.3
4.2
7.84
6.57
mmol/l
4.93
131
1007
109
779
1.84
4.47
2.3
2.1
108.49
95.89
pmol/l
1.30
54
382
112
810
1.83
4.39
9.0
14.3
1.19
1.21
inr
0.23
101
659
129
980
1.83
4.25
5.0
4.3
0.03
0.00
estimate
0.38
34
204
100
704
1.81
4.24
4.1
4.0
46.14
28.65
ng/l
0.50
67
489
130
996
1.81
4.10
5.1
4.3
0.00
0.02
estimate
0.68
31
192
8
10
8.26
4.10
2.5
1.3
—
—
—
0
0
9
14
6.66
4.03
2.3
1.6
—
—
—
0
0
129
990
1.80
4.01
5.0
4.3
0.00
0.00
estimate
-0.00
35
207
30
141
2.32
3.94
6.4
4.2
7.39
7.32
ph
2.05
24
101
80
536
1.80
3.93
1.8
1.6
18.95
21.07
nmol/l
0.79
75
450
104
764
1.72
3.64
4.8
4.1
0.14
0.05
estimate
0.40
28
175
60
377
1.83
3.59
1.6
1.3
2.16
2.38
g/l
0.45
37
232
22
94
2.50
3.55
1.4
1.2
106.10
78.94
u/ml
0.17
13
31
56
351
1.81
3.36
3.2
2.9
502.77
494.16
mosm/kgh2o
0.10
48
303
39
218
1.97
3.31
1.7
1.3
—
—
—
0
0
63
413
1.75
3.24
3.3
2.5
6.20
5.47
e6/l
0.15
54
374
106
803
1.65
3.17
4.0
3.7
6.19
6.23
ph
0.13
63
462
186
1655
2.17
3.06
14.0
4.0
1.83
1.88
mu/l
0.05
176
1533
19
84
2.39
2.87
2.6
1.7
16.04
5.35
iu/ml
—
5
20
61
409
1.70
2.86
1.5
1.4
24.46
30.26
iu/ml
0.20
19
134
27
139
2.08
2.86
1.3
1.1
—
—
—
0
0
77
550
1.64
2.83
4.2
3.5
0.04
0.02
estimate
0.20
27
169
105
814
1.59
2.73
7.3
3.6
34.97
36.00
g/l
1.18
100
767
57
380
1.69
2.72
1.5
1.3
3.77
12.29
u/ml
1.58
25
144
18
80
2.37
2.69
1.2
1.3
—
—
—
0
0
33
187
1.91
2.69
5.8
2.9
7.38
7.39
ph
0.06
19
114
62
424
1.66
2.68
1.5
1.3
0.73
1.89
u/ml
—
9
122
29
158
1.97
2.64
6.9
4.9
1.06
0.76
%
—
8
48
76
552
1.59
2.57
5.1
4.3
0.00
0.01
estimate
0.50
31
191
14
58
2.52
2.42
1.2
1.3
—
—
—
0
0
27
150
1.92
2.34
6.9
5.0
0.00
0.08
%
—
6
40
5
9
5.66
2.22
1.6
1.1
23.40
22.96
nmol/l
—
5
9
8
24
3.42
2.20
2.3
1.2
—
—
—
0
0
59
420
1.57
2.12
1.7
1.6
1.29
1.24
mg/l
0.03
47
344
26
148
1.86
2.10
6.5
4.8
0.50
0.60
%
—
5
43
21
111
1.99
2.10
6.5
5.5
25.18
24.96
mmol/l
0.08
21
111
13
56
2.41
2.09
1.0
1.3
—
2.56
—
0
8
13
56
2.41
2.09
5.4
3.0
358.75
147.83
mg/l
—
8
18
11
44
2.58
2.04
1.2
1.2
—
—
—
0
0
99
792
1.48
2.04
14.1
11.7
0.00
0.00
e9/l
0.21
83
651
74
560
1.50
2.00
6.2
3.2
7.39
7.40
ph
0.88
49
386
9
33
2.80
1.95
2.4
2.0
8.46
8.45
pmol/l
—
9
33
6
16
3.83
1.95
2.2
2.1
—
—
—
0
0
22
122
1.90
1.93
8.8
2.6
141.92
76.86
ng/l
0.81
16
108
25
145
1.82
1.92
4.9
3.6
1.22
1.23
mmol/l
0.27
19
127
17
86
2.06
1.91
2.6
2.7
0.00
0.00
estimate
—
5
27
75
574
1.48
1.91
5.2
6.3
—
—
—
0
0
8
28
2.93
1.88
1.8
1.2
30.98
11.66
u/l
—
8
23
18
94
2.00
1.87
1.8
1.3
—
—
—
0
0
77
595
1.47
1.86
4.6
3.1
30.07
181.32
e6/l
0.74
61
452
85
672
1.45
1.81
2.7
3.0
2.34
2.36
mmol/l
1.07
75
612
6
18
3.40
1.76
1.7
1.0
281.33
276.77
mosm/kgh2o
—
6
13
31
197
1.67
1.75
11.4
6.4
7.42
7.41
ph
0.27
11
110
5
14
3.63
1.62
1.0
1.1
—
—
—
0
0
67
516
1.44
1.62
4.3
2.9
0.58
0.38
e6/l
0.26
52
369
189
1766
1.77
1.58
25.6
14.9
23.35
22.84
mg/l
0.07
170
1442
27
172
1.65
1.52
2.7
2.5
0.00
0.00
estimate
—
6
33
6
21
2.91
1.51
1.0
1.2
—
—
—
0
0
24
149
1.69
1.49
11.5
5.7
—
—
—
0
0
58
441
1.44
1.49
2.6
2.2
334.78
326.17
umol/l
0.17
46
397
85
692
1.39
1.48
5.3
3.9
118.20
76.12
e6/l
0.28
66
473
31
207
1.58
1.46
1.3
1.3
—
—
—
0
0
73
583
1.39
1.41
2.6
2.2
—
—
—
0
0
28
184
1.60
1.41
12.5
6.4
94.65
95.70
%
0.51
28
179
17
97
1.82
1.39
10.4
4.3
—
—
—
0
0
20
121
1.72
1.36
1.4
1.7
—
—
—
0
0
57
439
1.41
1.36
7.3
4.6
—
—
—
0
0
5
18
2.82
1.29
1.6
1.1
—
—
—
0
0
9
44
2.09
1.28
1.1
1.0
—
—
—
0
0
8
35
2.34
1.28
1.0
3.7
—
—
—
0
0
179
1670
1.52
1.26
10.3
6.3
45.15
38.94
mmol/mol
7.33
169
1580
8
36
2.27
1.25
1.1
1.3
—
—
—
0
0
34
242
1.48
1.22
1.8
1.5
—
—
—
0
0
5
20
2.54
1.16
1.6
1.5
—
—
—
0
0
5
20
2.54
1.16
1.6
1.5
—
—
—
0
0
5
20
2.54
1.16
1.6
1.5
—
—
—
0
0
5
20
2.54
1.16
1.6
1.5
—
—
—
0
0
5
20
2.54
1.16
1.6
1.1
—
—
—
0
0
5
20
2.54
1.16
1.6
1.4
—
—
—
0
0
58
715
0.74
1.15
4.2
3.1
—
—
—
0
0
10
51
2.01
1.13
1.0
3.0
1.40
2.01
ratio
—
5
26
7
32
2.23
1.09
3.9
2.0
—
—
—
0
0
36
266
1.43
1.08
4.5
3.0
2.49
3.15
e6/l
0.21
18
124
7
34
2.09
1.04
1.7
1.6
—
—
—
0
0
98
849
1.29
1.04
3.2
2.6
—
—
estimate
—
0
0
22
148
1.54
1.03
4.1
3.8
—
—
—
0
0
17
108
1.63
1.00
11.6
7.0
23.05
24.74
mmol/l
0.91
17
102
10
54
1.89
0.98
3.7
1.9
1.91
1.36
mg/l
—
10
47
35
262
1.40
0.98
1.3
1.2
—
—
—
0
0
7
36
1.98
0.98
1.0
1.2
—
—
—
0
0
12
193
0.60
0.93
1.4
1.7
—
—
—
0
0
18
119
1.56
0.91
1.3
1.4
—
—
—
0
0
17
111
1.58
0.91
1.3
1.8
—
—
—
0
0
6
29
2.10
0.90
4.3
3.3
—
—
—
0
0
6
29
2.10
0.90
1.7
2.1
3.34
6.03
e9/l
—
6
29
8
42
1.94
0.89
3.7
1.5
136.50
125.87
g/l
—
8
31
36
276
1.37
0.88
1.7
1.8
—
—
—
0
0
15
96
1.61
0.87
3.7
4.4
1.02
1.02
ratio
0.05
15
88
55
452
1.29
0.85
4.9
4.1
1.02
1.02
kg/l
0.33
38
290
42
336
1.31
0.79
6.4
3.6
493.52
277.81
ng/l
0.23
33
250
29
221
1.36
0.75
4.1
3.4
4.02
6.14
e9/l
0.78
24
199
5
24
2.11
0.75
1.0
1.0
—
2.11
u/ml
—
0
12
7
38
1.87
0.74
2.4
1.8
65.29
57.49
%
—
7
38
5
25
2.02
0.73
6.6
3.1
—
—
—
0
0
17
121
1.44
0.64
11.2
7.1
92.94
94.11
%
0.38
17
121
16
113
1.45
0.63
4.2
2.5
1.27
1.14
%
0.38
16
113
8
49
1.66
0.63
4.1
4.0
22.05
32.74
mg/l
—
8
33
8
50
1.62
0.62
2.6
2.4
7.40
7.42
ph
—
8
50
187
1805
1.36
0.62
23.0
13.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
8
52
1.56
0.60
4.0
5.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
6
40
1.51
0.52
1.7
2.4
53.50
64.47
%
—
6
40
7
45
1.57
0.49
2.0
2.2
—
—
—
0
0
13
94
1.41
0.47
2.5
2.0
—
—
—
0
0
22
175
1.29
0.45
2.0
1.4
—
—
—
0
0
12
86
1.42
0.45
5.5
4.7
37.12
36.96
°c
0.35
12
86
5
31
1.63
0.43
1.0
1.0
—
0.37
u/ml
—
0
17
14
105
1.36
0.42
1.4
1.2
—
—
—
0
0
5
33
1.53
0.41
2.6
2.5
5.34
5.08
kpa
—
5
33
5
33
1.53
0.41
2.6
2.5
2.82
2.74
mmol/l
—
5
25
5
33
1.53
0.41
2.6
2.5
8.66
8.80
kpa
—
5
33
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
82
752
1.15
0.41
2.2
2.1
—
—
—
0
0
21
257
0.80
0.40
1.1
1.3
—
—
—
0
0
13
169
0.75
0.38
1.5
1.3
—
—
—
0
0
21
171
1.25
0.37
1.4
1.4
—
—
—
0
0
5
37
1.36
0.37
1.6
1.4
—
—
—
0
0
44
392
1.16
0.32
2.4
2.4
2.44
2.45
mmol/l
0.33
38
351
7
97
0.71
0.31
1.1
1.1
—
—
—
0
0
12
94
1.29
0.28
2.1
2.3
—
—
—
0
0
49
450
1.12
0.24
5.4
4.0
—
0.14
—
0
7
5
41
1.22
0.22
1.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
8.2
—
9.37
—
0
10
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
3.2
—
1.00
—
0
13
0
14
0.00
0.20
0.0
1.3
—
100.71
—
0
14
174
1708
1.11
0.19
6.3
5.0
6.63
5.86
mmol/l
3.88
160
1576
7
62
1.13
0.17
6.9
11.5
—
—
—
0
0
12
141
0.84
0.17
1.0
1.3
—
—
—
0
0
82
785
1.07
0.16
2.4
1.9
1.35
1.34
mmol/l
0.03
70
677
127
1235
1.07
0.16
4.5
3.0
73.09
42.15
u/l
1.60
121
1175
51
480
1.08
0.15
1.4
1.4
—
—
—
0
0
21
193
1.10
0.10
1.4
1.5
—
—
—
0
0
6
70
0.85
0.08
2.0
1.6
—
8.61
—
0
14
9
85
1.06
0.07
1.1
1.4
—
—
—
0
0
20
187
1.08
0.06
1.4
1.3
—
—
—
0
0
168
1671
1.03
0.02
6.1
4.1
1.32
1.23
mmol/l
0.95
157
1548
175
1757
0.97
0.01
7.2
4.9
4.58
4.74
mmol/l
1.30
165
1644
178
1786
0.98
0.00
7.9
5.6
2.57
2.76
mmol/l
2.00
165
1664
175
1754
0.99
0.00
7.0
4.8
1.55
1.55
mmol/l
0.05
161
1633
0
8
0.00
0.00
0.0
9.5
—
16.14
—
0
8
5
49
1.02
0.00
1.8
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
5.0
—
44.00
—
0
8
9
91
0.99
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
141.71
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
0.00
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_HYTHYPOSTINF and mortality.

Females

Parameter HR [95% CI] p-value
E4_HYTHYPOSTINF 1.889 [1.3, 2.75] < 0.001
Birth year 0.995 [0.99, 1.0] 0.278

During the follow-up period (1.1.1998 — 31.12.2019), 115 out of 430 females with E4_HYTHYPOSTINF died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_HYTHYPOSTINF.

N-year risk Females Males
1 0.184% No data
5 1.234% No data
10 2.848% No data
15 5.051% No data
20 9.149% No data

Relationships between endpoints

Index endpoint: E4_HYTHYPOSTINF – Postinfectious hypothyroidism

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data