Failed attempted abortion

O15_ABORT_FAILED

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O07
  • Hospital discharge: ICD-9 638
  • Cause of death: ICD-10 O07
  • Cause of death: ICD-9 638

2 out of 7 registries used, show all original rules.

520

4. Check minimum number of events

None

520

5. Include endpoints

None

520

6. Filter based on genotype QC (FinnGen only)

455

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O00-O08
Name in latin
Tentamen abortus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4502 4502 -
Only index persons 4450 4450 -
Unadjusted period prevalence (%)
Whole population 0.13 0.13 -
Only index persons 0.16 0.16 -
Median age at first event (years)
Whole population - 28.56 -
Only index persons - 28.54 -

-FinnGen-

Key figures

All Female Male
Number of individuals 455 455 -
Unadjusted period prevalence (%) 0.16 0.16 -
Median age at first event (years) 30.52 30.52 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
487
Matched controls
4870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
2680.8
307.7
369
6
LCH11
NOMESCO Finland
Pharmacologic abortion
390.6
307.7
217
10
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
125.2
226.2
115
12
O07.6
ICD-10 Finland
Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage
+∞
180.8
162
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
+∞
177.2
159
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
34.0
132.2
87
31
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
806.6
129.8
122
*
O07.4
ICD-10 Finland
Failed medical abortion, without complication
+∞
118.7
109
*
O07.1
ICD-10 Finland
Failed medical abortion, complicated by delayed or excessive haemorrhage
+∞
104.0
96
*
O02.1
ICD-10 Finland
Missed abortion
+∞
101.7
94
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
45.5
100.0
60
15
W79
ICPC
Unwanted pregnancy
44.6
97.9
59
15
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.4
70.5
196
536
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
82.9
58.7
65
9
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
55.3
52
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
53.1
50
*
O07.0
ICD-10 Finland
Failed medical abortion, complicated by genital tract and pelvic infection
+∞
46.6
44
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
46.6
44
*
R2110
NOMESCO Finland
Giving the first information
5.9
46.5
95
192
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
69.4
44.1
50
8
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
9.4
43.8
55
65
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.7
43.0
317
1622
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
40.2
38
*
WX400
NOMESCO Finland
Inhalation anesthesy
7.7
39.0
58
84
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
211.5
38.4
39
*
O20.0
ICD-10 Finland
Threatened abortion
8.6
37.3
50
64
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.7
37.1
160
572
ZXD05
NOMESCO Finland
Urgent procedure
3.2
35.6
239
1118
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.5
33.6
152
557
O07.9
ICD-10 Finland
Other and unspecified failed attempted abortion, without complication
+∞
32.7
31
*
P01AB01
ATC
metronidazole; oral, rectal
3.1
32.1
285
1537
8511
FHL
Cervical dilation and drainage with suction
+∞
31.6
30
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
333.2
31.2
31
*
O04.4
ICD-10 Finland
Medical abortion, incomplete, without complication
+∞
28.4
27
*
ZXE00
NOMESCO Finland
One hour or less
2.7
25.6
248
1351
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
4.8
25.2
62
145
W83
ICPC
Abortion induced
137.0
24.8
26
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
24.7
140
574
LCA10
NOMESCO Finland
Curettage of body of uterus
6.8
23.4
38
60
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
23.1
22
*
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
240.9
22.8
23
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
126.0
22.8
24
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
21.0
20
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
5.9
20.4
38
69
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
208.1
19.7
20
*
8502
FHL
Evacuation and abrasion
69.3
17.8
20
*
O07.3
ICD-10 Finland
Failed medical abortion, with other and unspecified complications
+∞
17.8
17
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
186.5
17.6
18
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
17.2
217
1270
ZXD20
NOMESCO Finland
Day surgery
3.0
16.8
84
316
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
88.0
15.7
17
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
15.7
127
610
6388X
ICD-9 Finland
Failed attempted abortion, With unspecified complication
+∞
14.7
14
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
14.6
211
1284
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.6
13.8
95
420
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
4.8
13.7
32
71
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
13.6
13
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
13.5
113
547
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
13.4
124
627
J01DB01
ATC
cefalexin; oral
3.0
13.2
437
3621
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.2
13.1
54
181
SPAT1260
SPAT
Consultation of another employee
2.5
12.9
93
420
SPAT1263
SPAT
Sampling
2.0
12.9
226
1459
N06AB10
ATC
escitalopram; oral
2.1
12.6
163
939
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
12.6
196
1210
O04.3
ICD-10 Finland
Medical abortion, incomplete, with other and unspecified complications
+∞
12.6
12
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.2
12.5
123
636
H01
ICPC
Ear pain/earache
2.4
12.1
99
472
SPAT1283
SPAT
Restricted health certificate
2.1
12.1
168
991
SPAT1371
SPAT
Assessment of need for induced abortion
47.9
11.9
14
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
11.7
172
1035
LCH96
NOMESCO Finland
Other termination of pregnancy
+∞
11.5
11
*
N06AX11
ATC
mirtazapine; oral
2.0
11.4
191
1200
ULC02
NOMESCO Finland
Hysteroscopy
3.4
11.4
43
136
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.2
11.2
110
566
D10
ICPC
Vomiting
2.8
11.2
62
245
D11
ICPC
Diarrhoea
2.3
11.0
96
471
N02AX02
ATC
tramadol; systemic, rectal
2.0
10.9
178
1106
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.9
10.9
184
1157
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
10.8
225
1515
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
4.4
10.7
27
64
SGC00
NOMESCO Finland
Medication, disinfection of root canals
2.4
10.6
79
360
O07.2
ICD-10 Finland
Failed medical abortion, complicated by embolism
+∞
10.5
10
*
6381A
ICD-9 Finland
Failed attempted abortion, Complicated by delayed or excessive haemorrhage
+∞
10.5
10
*
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
10.5
10
*
O07.8
ICD-10 Finland
Other and unspecified failed attempted abortion, with other and unspecified complications
+∞
10.5
10
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
10.4
134
764
Z2221
NOMESCO Finland
Medical doctor
2.0
10.3
164
1005
M54.5
ICD-10 Finland
Low back pain
1.9
10.3
219
1477
SPAT1301
SPAT
No procedures
2.0
10.2
145
855
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
3.6
9.9
33
96
N05BA04
ATC
oxazepam; oral
2.0
9.9
149
895
Z3232
NOMESCO Finland
Midwife
2.1
9.8
113
616
Z3231
NOMESCO Finland
Registered nurse
2.0
9.8
126
716
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
9.4
9
*
O04.8
ICD-10 Finland
Medical abortion, complete or unspecified, with other and unspecified complications
+∞
9.4
9
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.8
9.4
278
2058
XLA10, ,
NOMESCO Finland
3.5
9.3
32
95
W01
ICPC
Question of pregnancy
8.0
9.2
20
26
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
9.2
210
1434
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
9.1
223
1553
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.0
9.1
111
617
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.9
9.1
165
1049
S06.0
ICD-10 Finland
Concussion
2.5
9.1
59
252
M77.1
ICD-10 Finland
Lateral epicondylitis
2.4
9.0
68
311
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.7
9.0
28
78
N05CF02
ATC
zolpidem; oral
2.1
8.9
99
531
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
2.1
8.9
89
459
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.0
8.8
109
609
J01FF01
ATC
clindamycin; systemic
1.9
8.8
132
789
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
14.4
8.7
14
10
O04
ICD-10 Finland
Medical abortion
50.9
8.7
10
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.2
8.7
34
110
R42
ICD-10 Finland
Dizziness and giddiness
2.1
8.5
92
489
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.7
8.4
46
180
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
8.4
298
2293
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
8.4
8
*
O07.5
ICD-10 Finland
Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection
+∞
8.4
8
*
T74.1
ICD-10 Finland
Physical abuse
4.2
8.3
22
54
F43.0
ICD-10 Finland
Acute stress reaction
2.3
8.3
71
343
XMA22
NOMESCO Finland
General examination of pregnant woman
2.2
8.3
75
371
A03
ICPC
Fever
1.9
8.3
131
794
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
8.3
189
1282
J01AA02
ATC
doxycycline; systemic
1.9
8.2
369
3037
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.1
8.1
86
452
WX290
NOMESCO Finland
Other blockage of nerve
1.7
8.0
304
2372
Z87.4
ICD-10 Finland
Personal history of diseases of the genitourinary system
13.3
7.9
13
10
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
7.8
82
429
N05AH04
ATC
quetiapine; oral
1.9
7.8
113
664
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.1
7.8
83
438
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.6
91
500
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.5
7.6
50
215
Z37.0
ICD-10 Finland
Single live birth
1.9
7.6
117
701
R51.80
ICD-10 Finland
Headache
1.9
7.6
118
709
Z30.0
ICD-10 Finland
General counselling and advice on contraception
2.1
7.5
80
422
L12
ICPC
Hand/finger symptom/complaint
1.9
7.4
101
580
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
7.4
92
513
6380A
ICD-9 Finland
Failed attempted abortion, Complicated by genital tract and pelvic infection
+∞
7.3
7
*
8501
FHL
Emptying the uterus with suction
+∞
7.3
7
*
8519
FHL
Other measure in this category
+∞
7.3
7
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.7
7.3
262
1992
G02AB01
ATC
methylergometrine; systemic
16.0
7.3
11
7
X14
ICPC
Vaginal discharge
2.9
7.2
34
123
N96
ICD-10 Finland
Habitual aborter
30.5
7.2
9
*
Z09.7
ICD-10 Finland
Follow-up examination after combined treatment for other conditions
30.5
7.2
9
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.9
7.2
33
118
SGA02
NOMESCO Finland
Opening and preparing the root canals
2.1
7.1
70
358
D01
ICPC
Abdominal pain/cramps general
2.0
7.0
84
461
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
7.0
105
623
R74
ICPC
Upper respiratory infection acute
1.7
7.0
255
1940
J01DA01
ATC
[U] cefalexin
1.7
6.9
306
2443
I25.1
ICD-10 Finland
Atherosclerotic heart disease
4.4
6.8
17
40
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.8
106
636
SPAT1196
SPAT
Monitoring of normal pregnancy
1.9
6.7
91
521
SFA20
NOMESCO Finland
Two-surface restoration
1.7
6.6
328
2681
N01
ICPC
Headache
1.9
6.6
90
516
P01
ICPC
Feeling anxious/nervous/tense
1.8
6.6
124
786
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.8
6.6
106
641
LCA96
NOMESCO Finland
Other intrauterine operation
10.2
6.6
12
12
G02CB01
ATC
bromocriptine; systemic
3.7
6.5
20
55
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.8
6.5
109
667
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
6.5
191
1366
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
6.3
6.5
16
26
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
6.5
363
3055
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
6.5
102
612
N06AX21
ATC
duloxetine; oral
2.0
6.5
74
399
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.9
6.5
88
504
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
2.2
6.4
56
272
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
6.4
100
598
W17
ICD-10 Finland
Other fall from one level to another
3.1
6.4
26
86
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
6.4
136
891
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
6.4
58
286
WX702
NOMESCO Finland
Supraglottic ventilation device
2.8
6.4
31
114
G01AA10
ATC
clindamycin; vaginal
1.8
6.4
110
679
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
6.4
79
439
L03
ICPC
Low back symptom/complaint
1.7
6.4
163
1125
A01
ICPC
Pain general/multiple sites
2.3
6.3
51
240
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
6.3
59
295
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.9
6.3
86
493
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
6.3
93
547
N06AX16
ATC
venlafaxine; oral
1.8
6.3
96
571
K10.3
ICD-10 Finland
Alveolitis of jaws
2.5
6.3
38
157
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.6
6.3
179
1269
O06.1
ICD-10 Finland
Unspecified abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
O04.5
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by genital tract and pelvic infection
+∞
6.3
6
*
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
+∞
6.3
6
*
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.5
6.2
21
62
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.1
6.2
26
88
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
6.2
101
613
H92.0
ICD-10 Finland
Otalgia
2.3
6.2
49
229
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.7
6.2
163
1132
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.0
6.1
27
94
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
4.2
6.1
16
39
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.1
6.1
56
278
M03BX02
ATC
tizanidine; oral
1.6
6.1
323
2657
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.3
6.1
23
73
D06
ICPC
Abdominal pain localized other
2.1
6.1
59
300
N06AB04
ATC
citalopram; systemic
1.8
6.0
101
618

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
93
374
2.84
16.47
2.3
1.7
—
—
—
0
0
77
279
3.09
16.43
1.5
1.3
—
—
—
0
0
171
998
2.10
12.83
3.8
3.1
1.02
2.59
kg/l
0.50
108
642
102
491
2.36
12.25
2.5
2.5
8.87
4.65
e6/l
1.45
59
223
101
507
2.25
10.91
2.8
1.7
10979.44
10955.78
u/l
0.00
54
147
196
1317
1.82
9.02
5.9
6.5
—
—
—
0
0
170
1095
1.85
8.97
3.7
2.8
38.37
92.19
e6/l
0.89
132
819
348
2804
1.84
8.40
5.5
3.7
353.38
550.41
e6/l
—
8
29
148
931
1.85
8.32
3.1
2.6
0.20
0.31
e6/l
0.64
111
669
193
1318
1.77
8.24
2.3
1.9
—
—
—
0
0
109
623
1.97
8.19
2.5
2.6
530.51
513.89
mosm/kgh2o
0.31
93
564
432
3787
2.25
7.60
5.6
5.0
14.06
14.16
pmol/l
0.42
410
3650
86
468
2.02
7.38
2.0
1.5
—
—
—
0
0
202
1431
1.70
7.36
4.4
3.3
54.68
36.62
e6/l
0.29
140
923
39
155
2.65
6.95
3.3
2.2
—
—
—
0
0
116
718
1.81
6.70
3.3
2.4
10.09
8.99
e6/l
0.28
101
667
60
297
2.16
6.59
3.3
1.6
—
—
—
0
0
56
272
2.20
6.45
4.4
2.3
—
—
—
0
0
257
1989
1.62
6.33
3.2
2.5
—
—
estimate
—
0
0
263
2050
1.62
6.27
6.1
6.2
0.64
0.68
%
0.46
251
1937
68
364
2.01
6.08
3.2
1.7
—
—
—
0
0
445
4023
2.23
6.01
11.8
9.4
139.40
139.47
mmol/l
0.29
438
3944
261
2047
1.59
5.94
6.0
6.1
2.71
2.68
%
0.09
248
1946
68
367
1.99
5.94
3.4
1.7
—
—
—
0
0
262
2057
1.59
5.93
6.2
6.2
7.84
8.04
%
0.75
251
1959
64
340
2.02
5.84
3.3
1.7
—
—
—
0
0
67
362
1.99
5.83
3.2
1.7
—
—
—
0
0
67
364
1.97
5.74
3.2
1.7
—
—
—
0
0
281
2253
1.58
5.74
5.7
6.2
0.52
0.52
e9/l
0.07
250
2019
157
1097
1.64
5.74
2.7
2.2
—
—
—
0
0
14
23
6.23
5.73
1.6
2.5
—
—
—
0
0
345
2906
1.64
5.72
7.8
6.7
68.86
69.73
u/l
0.27
323
2784
281
2256
1.58
5.68
5.7
6.3
0.04
0.04
e9/l
0.19
247
2019
458
4209
2.48
5.61
6.6
5.8
1.59
1.70
mu/l
1.74
443
4112
464
4290
2.73
5.60
14.7
10.4
16.41
17.68
mg/l
0.48
387
3401
444
4031
2.15
5.59
11.9
9.4
3.88
3.89
mmol/l
0.41
436
3938
140
974
1.61
5.12
1.4
1.3
3.53
11.95
u/ml
2.65
66
437
264
2124
1.53
5.04
6.0
5.9
56.66
56.90
%
0.15
253
2046
159
1150
1.57
4.90
4.9
5.8
—
—
—
0
0
285
2342
1.52
4.85
5.8
6.5
0.18
0.18
e9/l
0.39
255
2126
237
1881
1.51
4.71
3.8
2.8
6.32
6.22
ph
0.70
133
1132
283
2332
1.51
4.68
5.8
6.2
2.03
2.00
e9/l
0.19
256
2140
181
1359
1.53
4.68
4.8
5.1
1.21
1.22
mmol/l
0.51
174
1266
264
2147
1.50
4.64
6.0
6.0
29.83
29.51
%
0.25
256
2066
283
2339
1.50
4.57
4.2
3.3
0.00
0.01
estimate
0.50
56
487
144
1036
1.55
4.49
1.9
1.7
0.98
0.78
mg/l
0.28
109
786
159
1172
1.53
4.43
6.1
5.1
1.05
1.03
inr
0.22
135
983
278
2300
1.49
4.39
4.1
3.2
0.00
0.00
estimate
0.50
59
499
281
2332
1.48
4.35
4.0
3.2
20.90
0.00
estimate
0.49
58
498
295
2476
1.49
4.29
8.2
8.8
3.98
4.00
e9/l
0.04
263
2201
130
936
1.53
3.98
3.8
3.5
7.40
7.39
ph
0.36
90
639
236
1916
1.45
3.95
8.8
8.9
0.00
0.00
e9/l
0.65
176
1572
150
1115
1.50
3.95
3.1
2.4
51.43
57.62
u/l
1.71
141
1052
224
1807
1.44
3.85
5.5
5.1
8.81
9.19
umol/l
0.49
210
1718
142
1050
1.50
3.82
1.5
1.3
15.67
21.07
iu/ml
0.90
46
333
75
480
1.66
3.75
2.3
1.8
—
—
—
0
0
111
782
1.54
3.73
1.4
1.4
848.00
585.03
titre
0.43
20
171
66
413
1.69
3.59
1.8
1.8
30.07
29.04
s
0.60
61
400
248
2057
1.42
3.57
4.0
4.1
6.02
6.24
mmol/l
1.04
226
1854
76
496
1.63
3.52
2.0
2.2
347.34
373.57
nmol/l
0.72
68
465
136
1013
1.48
3.49
2.7
2.3
23.62
21.72
ng/l
0.05
46
364
194
1545
1.42
3.49
6.1
5.7
1.22
1.22
mmol/l
0.46
175
1351
332
2909
1.44
3.47
3.8
3.3
58.80
56.71
ug/l
0.20
318
2814
70
451
1.64
3.42
1.2
1.2
—
—
—
0
0
82
557
1.57
3.22
1.2
1.2
—
—
—
0
0
95
670
1.52
3.16
3.7
3.7
—
—
—
0
0
468
4464
2.24
3.12
11.1
9.1
24.43
22.94
u/l
0.54
458
4393
419
3879
1.57
3.04
17.1
12.8
13.31
13.27
%
0.27
419
3829
199
1630
1.37
2.91
1.8
1.7
1.23
1.29
mmol/l
0.72
182
1497
182
1471
1.38
2.88
2.7
3.0
27.58
26.35
u/l
0.20
175
1410
418
3881
1.54
2.84
4.0
3.6
5.59
5.53
mmol/l
0.39
397
3742
184
1494
1.37
2.82
2.0
1.8
97.96
97.22
pmol/l
0.09
101
886
72
497
1.53
2.64
3.5
2.4
18.94
430.32
ng/l
1.10
32
204
53
342
1.62
2.59
4.6
4.9
0.00
1.40
%
0.56
11
62
51
327
1.63
2.56
3.7
4.5
0.64
0.74
%
0.07
11
73
209
1755
1.33
2.50
2.4
2.1
—
—
—
0
0
472
4549
2.22
2.50
12.9
9.5
—
—
—
0
0
53
346
1.60
2.48
4.1
4.6
0.58
0.89
%
0.29
12
81
95
705
1.43
2.43
1.5
1.4
18.82
23.56
iu/l
0.88
78
621
47
300
1.63
2.41
1.1
1.1
—
—
—
0
0
40
247
1.67
2.33
2.1
2.3
6.83
7.99
iu/ml
0.11
12
59
51
339
1.56
2.23
4.3
4.7
0.10
0.09
%
—
10
74
5
9
5.60
2.22
1.0
1.2
—
—
—
0
0
215
1837
1.31
2.20
4.0
2.9
0.00
0.04
estimate
2.03
46
424
12
48
2.54
2.20
1.1
1.5
—
—
—
0
0
28
159
1.81
2.18
1.6
1.9
19.09
19.64
s
0.70
22
133
156
1279
1.32
2.14
2.0
1.7
—
—
—
0
0
22
117
1.92
2.09
4.7
7.7
94.01
93.70
%
0.11
22
117
170
1416
1.31
2.08
1.4
1.4
2.65
1.37
u/ml
0.26
47
421
31
185
1.72
2.06
4.5
9.3
124.77
119.39
g/l
0.69
31
179
103
801
1.36
2.00
1.6
1.6
—
—
—
0
0
37
235
1.62
1.97
3.9
8.2
7.42
7.41
ph
0.24
18
135
28
165
1.74
1.95
3.4
2.1
5.70
4.83
umol/l
0.27
23
127
174
1464
1.29
1.95
1.8
1.7
—
—
—
0
0
5
11
4.58
1.94
1.2
2.5
11.46
23.59
ug/l
—
5
11
51
352
1.50
1.90
1.8
1.8
0.00
0.08
estimate
1.05
14
105
44
294
1.55
1.90
3.8
5.5
105.70
105.11
mmol/l
0.53
44
294
149
1232
1.30
1.90
4.4
3.3
0.00
0.00
estimate
0.80
56
492
31
191
1.67
1.86
4.2
9.1
95.45
96.24
%
0.26
31
183
5
12
4.20
1.82
2.2
1.0
104.80
76.08
ng/l
—
5
12
94
732
1.35
1.81
2.0
2.1
—
—
—
0
0
27
162
1.71
1.79
1.1
1.3
52.24
46.74
u/ml
—
5
18
122
993
1.31
1.73
4.4
3.3
7.85
8.12
mmol/l
0.22
103
900
35
228
1.58
1.70
1.3
1.3
—
—
—
0
0
30
190
1.62
1.64
2.5
3.6
2.19
3.96
ug/l
1.18
22
136
142
1188
1.28
1.63
1.5
1.4
2.01
2.06
g/l
0.29
85
846
10
42
2.41
1.62
1.0
1.1
—
—
—
0
0
353
3281
1.28
1.61
3.2
2.9
28.86
28.58
u/l
0.05
347
3195
47
332
1.46
1.59
1.3
1.3
235.35
234.99
miu/ml
0.00
23
176
217
1915
1.24
1.56
2.2
1.9
—
—
—
0
0
45
317
1.46
1.55
1.2
1.2
—
—
—
0
0
35
234
1.53
1.54
4.1
8.1
-0.66
0.42
mmol/l
0.58
26
176
72
554
1.35
1.51
1.4
1.2
129.45
151.28
u/ml
0.28
28
235
6
21
2.88
1.51
3.8
2.5
329.67
667.52
u/ml
—
6
21
168
1448
1.24
1.48
3.4
2.6
0.00
0.02
estimate
1.34
46
431
9
38
2.39
1.46
1.1
1.1
—
—
—
0
0
109
894
1.28
1.46
2.7
2.0
289.26
289.70
umol/l
0.02
99
827
104
850
1.28
1.43
2.8
2.2
—
—
—
0
0
15
81
1.88
1.41
1.7
1.5
0.30
0.53
g/l
—
10
60
67
516
1.35
1.40
1.3
1.5
—
—
—
0
0
10
47
2.15
1.34
1.0
1.2
0.64
0.44
nmol/l
—
10
47
33
226
1.49
1.33
2.5
2.9
—
—
—
0
0
31
210
1.51
1.31
1.7
1.3
22.72
23.54
u/l
0.05
25
176
165
1436
1.23
1.31
5.9
4.5
37.12
37.46
g/l
0.38
155
1368
50
372
1.38
1.31
1.5
1.4
—
—
—
0
0
6
24
2.52
1.30
5.0
3.8
—
—
—
0
0
132
1124
1.24
1.28
2.7
2.2
2.42
2.47
mg/l
0.13
110
1005
28
188
1.52
1.24
2.0
2.6
4.17
4.13
iu/l
0.01
16
96
51
665
0.74
1.24
1.4
1.6
3.35
3.38
mmol/l
0.07
32
435
9
45
2.02
1.24
1.6
2.0
—
—
—
0
0
50
376
1.37
1.23
1.6
1.5
—
—
—
0
0
49
368
1.37
1.22
1.2
1.2
—
—
—
0
0
49
368
1.37
1.22
1.5
1.4
1.32
1.26
mm
0.39
31
267
34
240
1.45
1.19
1.2
1.3
11.40
12.76
u/l
0.19
28
200
48
363
1.36
1.15
2.5
2.3
12.08
19.50
au/ml
—
5
61
0
35
0.00
1.15
0.0
1.4
—
64.74
—
0
35
60
472
1.31
1.11
1.5
1.4
56.88
62.25
ug/l
0.53
46
395
27
185
1.49
1.11
1.6
1.9
0.00
0.04
estimate
1.08
12
85
7
31
2.28
1.10
1.1
1.1
—
—
—
0
0
11
59
1.88
1.08
1.3
1.3
—
—
—
0
0
95
800
1.23
1.03
2.8
2.7
104.62
93.91
ug/g
0.17
73
632
430
4160
1.29
1.01
3.9
3.8
4.78
4.78
mmol/l
0.01
417
4060
31
224
1.41
0.99
1.4
1.4
0.22
0.22
mg/l
0.01
14
81
11
61
1.82
0.99
1.1
1.1
—
—
—
0
0
59
473
1.28
0.97
1.3
1.4
—
—
—
0
0
35
262
1.36
0.92
3.8
2.4
1.46
1.71
%
1.30
35
244
11
63
1.76
0.90
2.1
2.2
—
—
—
0
0
223
2049
1.16
0.90
2.5
2.6
72.35
73.77
nmol/l
0.37
218
1971
53
424
1.28
0.89
2.3
2.4
4.34
4.78
umol/l
0.42
48
354
19
128
1.50
0.87
2.6
9.0
23.91
24.01
mmol/l
0.06
19
120
54
435
1.27
0.87
1.8
1.6
1259.91
1180.77
nmol/l
0.26
45
347
24
170
1.43
0.87
2.9
2.6
59.20
74.79
e9/l
1.64
16
125
23
319
0.71
0.85
1.0
1.1
0.89
0.86
g/l
0.38
23
319
43
338
1.30
0.84
1.3
1.3
44.30
22.89
au/ml
—
5
22
8
46
1.75
0.83
1.3
1.2
—
—
—
0
0
8
46
1.75
0.83
1.3
1.2
—
—
—
0
0
8
46
1.75
0.83
1.3
1.2
—
—
—
0
0
8
46
1.75
0.83
1.3
1.2
—
—
—
0
0
16
105
1.54
0.82
1.1
1.4
185.50
182.00
u/ml
—
10
71
14
89
1.59
0.82
1.6
1.5
—
—
—
0
0
23
315
0.72
0.80
1.0
1.1
1.61
1.59
g/l
0.12
23
315
16
106
1.53
0.80
1.8
8.8
—
—
—
0
0
6
33
1.83
0.79
1.0
1.1
—
—
—
0
0
18
123
1.48
0.78
1.1
1.2
—
—
—
0
0
6
34
1.77
0.76
2.3
1.8
1.95
1.68
mmol/l
—
6
34
13
83
1.58
0.75
2.7
10.3
1.45
1.09
mmol/l
1.20
13
72
58
482
1.23
0.73
2.2
3.5
0.82
0.83
mmol/l
0.51
52
463
386
3725
1.17
0.73
4.6
4.2
36.83
36.65
mmol/mol
0.14
367
3625
427
4157
1.22
0.73
3.9
3.7
1.53
1.53
mmol/l
0.02
410
4048
18
126
1.45
0.71
7.0
6.9
—
—
—
0
0
92
803
1.18
0.71
1.6
1.4
1215.49
1051.10
mu/l
0.68
75
660
5
26
1.93
0.71
1.6
1.3
—
—
—
0
0
52
430
1.23
0.69
1.5
1.8
294.28
316.97
mu/l
0.27
47
392
22
295
0.73
0.69
1.0
1.1
—
0.57
—
0
27
19
136
1.41
0.68
1.1
1.2
—
—
—
0
0
136
1233
1.14
0.64
3.6
2.9
2.32
2.34
mmol/l
0.97
124
1159
16
222
0.71
0.63
1.8
1.6
9.73
8.16
u/ml
—
6
64
11
71
1.56
0.62
1.0
1.0
—
—
—
0
0
8
50
1.61
0.61
1.4
1.1
—
—
—
0
0
8
51
1.58
0.60
1.4
1.7
—
—
—
0
0
20
148
1.37
0.60
1.6
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
905.18
—
0
17
6
35
1.72
0.58
1.3
1.4
4.82
5.10
mmol/l
—
6
35
428
4186
1.19
0.57
4.2
4.0
2.85
2.85
mmol/l
0.01
413
4072
20
150
1.35
0.56
1.4
1.5
275.73
362.94
mu/l
0.88
15
118
8
55
1.46
0.56
1.9
2.8
—
—
—
0
0
13
90
1.46
0.56
1.1
1.0
—
—
—
0
0
43
510
0.83
0.54
1.6
1.7
—
—
—
0
0
11
74
1.50
0.54
1.9
2.3
0.00
1.88
index
—
5
33
42
351
1.22
0.53
2.8
2.5
30.43
35.22
u/l
0.67
35
291
13
91
1.44
0.53
1.2
1.1
—
—
—
0
0
21
161
1.32
0.52
1.2
1.1
—
—
—
0
0
103
930
1.14
0.52
1.6
1.5
19.32
20.58
nmol/l
0.49
94
848
16
118
1.37
0.51
2.4
3.0
276.50
364.29
mg/l
—
8
48
13
93
1.41
0.48
1.5
4.5
37.15
36.99
°c
0.80
13
93
7
47
1.50
0.47
2.0
1.8
56.71
65.22
%
—
7
47
19
146
1.31
0.47
5.1
5.3
23.13
24.13
mmol/l
0.76
19
146
7
49
1.43
0.46
4.3
2.1
9.56
9.57
kpa
—
7
49
7
49
1.43
0.46
4.3
2.1
4.86
4.87
kpa
—
7
49
18
138
1.32
0.46
1.2
1.1
—
—
—
0
0
18
138
1.32
0.46
1.2
1.1
—
—
—
0
0
22
174
1.28
0.45
1.0
1.1
0.27
1.03
u/ml
—
10
69
22
174
1.28
0.45
1.0
1.1
0.25
1.01
u/ml
2.13
11
78
7
50
1.41
0.45
2.9
15.2
107.86
104.98
mmol/l
—
7
45
7
50
1.41
0.45
2.9
15.2
11.71
11.22
mmol/l
—
7
45
23
184
1.26
0.44
7.7
7.3
—
—
—
0
0
113
1039
1.11
0.43
1.7
1.6
—
—
—
0
0
25
203
1.24
0.43
2.5
1.7
—
—
—
0
0
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.2
1.7
5.52
6.07
mmol/l
—
5
24
0
16
0.00
0.41
0.0
1.1
—
0.02
—
0
16
8
59
1.36
0.41
1.3
1.2
—
—
—
0
0
23
187
1.24
0.39
1.1
1.1
1.36
5.27
u/ml
—
9
95
6
42
1.43
0.35
1.0
1.5
11.83
34.16
umol/l
—
6
37
55
492
1.13
0.34
1.3
1.3
—
—
—
0
0
6
44
1.37
0.34
1.0
1.0
—
—
—
0
0
19
232
0.81
0.34
1.2
1.4
0.40
0.47
nmol/l
0.35
14
196
13
100
1.31
0.34
1.4
1.2
—
—
—
0
0
80
735
1.11
0.32
1.2
1.3
—
—
—
0
0
11
84
1.32
0.30
1.6
3.7
3.15
4.32
e9/l
1.46
11
84
61
555
1.11
0.30
2.8
3.0
4.24
4.82
e9/l
0.48
56
509
41
367
1.13
0.27
1.7
2.0
46.14
36.36
u/ml
0.16
41
352
24
206
1.17
0.26
1.1
1.1
2.66
1.82
u/ml
0.13
11
111
12
95
1.27
0.26
1.1
1.3
10.00
4.43
u/ml
—
5
42
40
358
1.13
0.26
2.6
2.0
6.22
6.15
ph
0.22
27
203
10
77
1.30
0.26
3.5
2.0
7.40
7.41
ph
—
10
77
5
74
0.67
0.26
1.6
1.9
0.18
1.50
ug/l
—
5
67
24
277
0.86
0.26
1.0
1.1
—
—
—
0
0
9
77
1.17
0.24
1.2
1.7
18.03
22.72
ng/l
—
9
77
18
153
1.18
0.22
1.2
1.2
—
—
—
0
0
43
392
1.11
0.22
4.2
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
3.9
—
16.11
—
0
11
0
11
0.00
0.21
0.0
1.0
—
3.39
—
0
5
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
6.10
—
0
13
0
13
0.00
0.21
0.0
2.7
—
0.62
—
0
13
13
155
0.83
0.20
2.4
2.6
5.17
5.14
kpa
0.07
13
147
16
136
1.18
0.20
1.0
1.1
2.20
6.44
u/ml
—
7
48
0
14
0.00
0.20
0.0
1.1
—
65.44
—
0
14
18
155
1.17
0.20
3.3
2.2
1.02
1.02
ratio
0.19
18
140
6
49
1.23
0.20
1.5
1.5
—
—
—
0
0
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
6
52
1.16
0.19
1.0
1.2
—
—
—
0
0
17
147
1.16
0.18
2.0
2.1
—
—
—
0
0
7
58
1.21
0.18
2.7
1.6
—
—
—
0
0
13
110
1.19
0.17
1.2
1.7
—
—
—
0
0
5
67
0.74
0.17
1.0
1.4
—
—
—
0
0
64
606
1.06
0.15
2.3
2.0
2.40
2.40
mmol/l
0.01
52
546
82
783
1.06
0.15
5.5
4.2
7.94
8.42
mg/mmol
0.04
47
506
9
82
1.10
0.15
1.7
1.8
—
—
—
0
0
9
83
1.09
0.14
1.0
1.2
—
—
—
0
0
13
113
1.15
0.13
2.0
3.0
0.68
0.66
%
0.13
13
113
9
108
0.83
0.13
1.2
1.1
—
—
—
0
0
18
161
1.12
0.13
1.1
1.3
—
—
—
0
0
9
110
0.81
0.13
1.1
1.3
—
—
—
0
0
30
278
1.08
0.12
1.6
1.4
—
—
—
0
0
19
172
1.11
0.11
1.2
1.3
—
—
—
0
0
392
3888
1.04
0.11
3.3
3.2
1.19
1.16
mmol/l
0.39
373
3765
165
1614
1.03
0.11
2.1
1.7
—
—
—
0
0
13
144
0.90
0.08
4.3
1.9
—
—
—
0
0
6
71
0.84
0.07
1.0
2.2
5.40
4.97
mmol/24h
—
6
65
8
92
0.87
0.07
2.3
2.9
—
—
—
0
0
52
504
1.04
0.05
1.2
1.2
—
—
—
0
0
42
433
0.97
0.04
1.4
1.4
—
—
—
0
0
75
736
1.02
0.04
1.7
1.6
398.01
33968202.85
pmol/l
1.08
70
683
23
220
1.05
0.03
6.8
4.1
7.37
7.39
ph
0.91
12
125
212
2131
0.99
0.02
2.4
2.3
—
—
—
0
0
10
96
1.04
0.00
13.7
3.6
23.47
24.83
mmol/l
—
10
90
15
153
0.98
0.00
1.0
1.0
1.15
2.93
u/ml
—
7
62
11
108
1.02
0.00
1.6
3.6
49.73
59.21
%
1.00
11
108
27
267
1.01
0.00
5.3
3.0
7.23
7.33
ph
0.64
22
195
126
1263
1.00
0.00
3.6
4.0
—
—
—
0
0
78
777
1.00
0.00
4.8
3.6
55.41
41.80
mg/l
0.18
45
521
0
7
0.00
0.00
0.0
1.9
—
2.34
—
0
7
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
27.86
—
0
7
0
8
0.00
0.00
0.0
1.3
—
33.81
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
1.19
—
0
8
0
7
0.00
0.00
0.0
4.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
13.23
—
0
6
7
69
1.01
0.00
2.3
1.9
13.33
5.46
pmol/l
—
7
69
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
96.04
—
0
5
7
76
0.92
-0.00
1.9
1.5
7.96
7.06
mmol/l
—
7
76
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
210.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
139.20
—
0
5
0
5
0.00
-0.00
0.0
5.8
—
0.22
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
410.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
32.40
—
0
5
5
59
0.85
-0.00
2.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.03
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_ABORT_FAILED and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_ABORT_FAILED.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_ABORT_FAILED – Failed attempted abortion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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