brain neoplasm: A neoplasm (disease) that involves the brain.
Melanocytic naevi of scalp and neck
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_SCALPNECK
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1043 |
4. Check minimum number of eventsNone |
1043 |
5. Include endpointsNone |
1043 |
6. Filter based on genotype QC (FinnGen only) |
957 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D22
- Name in latin
- Naevus melanocyticus (cutis) verticis cranii
Melanocytic naevi of scalp and neck
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6814 | 3784 | 3011 |
| Only index persons | 6315 | 3553 | 2762 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.08 |
| Only index persons | 0.12 | 0.13 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 35.03 | 34.26 | 35.95 |
| Only index persons | 36.18 | 35.14 | 37.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 957 | 589 | 368 |
| Unadjusted period prevalence (%) | 0.19 | 0.21 | 0.17 |
| Median age at first event (years) | 47.90 | 42.22 | 56.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 981
- Matched controls
- 9810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
5571.8
307.7
945
46
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
18.4
307.7
425
391
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
7.0
108.1
186
318
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
5.5
77.6
167
350
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.1
76.9
184
423
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
10.8
70.8
79
79
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
9.2
49.2
61
70
TQW99
NOMESCO Finland
Other minor procedure on skin
5.3
46.4
100
207
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
7.4
42.4
63
90
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
4.1
38.4
115
309
2164A
ICD-9 Finland
Benign neoplasm of skin, Scalp and skin of neck[PÄÄN JA KAULAN IHON BEN KASV,NAEVUS PIGMENTOSUS]
+∞
37.7
36
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.4
30.7
282
1419
L57.0
ICD-10 Finland
Actinic keratosis
3.2
30.2
136
476
L82
ICD-10 Finland
Seborrhoeic keratosis
2.5
30.1
228
1049
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.6
28.8
101
302
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
3.6
27.6
95
280
XQ845
NOMESCO Finland
Dermatoscopy
6.4
26.4
44
71
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.0
26.0
57
119
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.7
25.3
48
88
XQ848
NOMESCO Finland
Dermatological photography
4.4
20.5
53
127
ZZR00
NOMESCO Finland
Flap of skin
6.0
20.2
36
62
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
4.9
19.1
42
88
9733
FHL
Excision of skin change in operating room or anesthesia
6.2
18.7
32
53
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.5
17.9
35
66
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
5.8
17.8
33
59
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.4
17.5
44
103
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.6
17.0
41
93
S82
ICPC
Naevus/mole
2.1
16.9
176
910
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.8
16.5
37
79
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.9
16.4
49
131
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.0
16.1
75
266
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
15.7
15
*
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
5.3
15.4
31
60
D23.4
ICD-10 Finland
Benign neoplasm: Skin of scalp and neck
5.5
15.0
29
54
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
152.2
14.5
15
*
Z94.0
ICD-10 Finland
Kidney transplant status
6.6
13.7
22
34
127
Kela drug reimbursment
Transplant complication
5.4
13.3
26
49
S18
ICPC
Laceration/cut
1.6
12.7
455
3389
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
11.2
12.6
23
21
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
17.6
12.5
19
11
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
5.3
11.6
23
44
L72.1
ICD-10 Finland
Trichilemmal cyst
2.4
11.2
78
339
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
4.6
11.0
26
58
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
15.7
10.8
17
11
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
4.4
10.6
26
60
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.4
9.9
35
105
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.5
9.8
65
276
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
4.6
9.8
23
51
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
17.7
9.4
14
8
C43.49
ICD-10 Finland
Malignant melanoma of the scalp and neck other or unspecified histology
+∞
9.4
9
*
SPAT1153
SPAT
Removal of sutures
1.6
9.4
275
1919
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
6.7
8.7
21
32
ZXC50
NOMESCO Finland
Cryotherapy
3.3
8.5
32
100
C43
ICD-10 Finland
Malignant melanoma of skin
27.8
8.5
11
*
PJA12
NOMESCO Finland
Sentinel node biopsy
2.2
8.5
73
348
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
9.5
8.3
16
17
D06BB10
ATC
imiquimod; topical
2.3
8.2
61
274
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
17.3
8.1
12
7
L91.0
ICD-10 Finland
Hypertrophic scar
3.9
8.0
23
60
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
7.3
8.0
18
25
L04AA01
ATC
[U] ciclosporin
6.0
7.7
20
34
ZXA00
NOMESCO Finland
Right side
1.6
7.7
213
1458
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.5
7.6
25
72
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
13.5
7.4
12
9
J01DB01
ATC
cefalexin; oral
1.6
7.3
792
7123
TQW40, ,
SPAT
1.9
7.3
100
565
C08CA02
ATC
felodipine; oral
2.0
7.0
73
375
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.6
6.9
15
20
D22
ICD-10 Finland
Melanocytic naevi
2.1
6.8
63
310
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.5
6.8
41
168
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
16.8
6.8
10
6
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
16.8
6.8
10
6
A54
ICPC
General and Unspecified, Repair/fix-suture/cast/prosth device
3.2
6.6
25
79
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
10.1
6.5
12
12
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
6.5
34
129
L04AD01
ATC
ciclosporin; systemic
3.6
6.5
21
60
L04AX01
ATC
azathioprine; systemic
2.4
6.4
42
179
A98
ICPC
Health maint/preventive medicine
2.8
6.4
957
9164
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
9.3
6.3
12
13
Z2221
NOMESCO Finland
Medical doctor
1.5
6.1
247
1824
TQW80
NOMESCO Finland
Local dermatologic skincare
2.9
6.1
27
94
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.1
221
1599
D22.1
ICD-10 Finland
Melanocytic naevi of eyelid, including canthus
10.1
6.0
11
11
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
10.1
6.0
11
11
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
6.0
79
440
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
443
3561
1.44
7.28
6.3
5.1
36.62
36.22
g/l
0.80
428
3360
905
8445
1.92
7.09
17.7
14.6
22.09
22.61
mg/l
0.18
736
6944
103
602
1.79
6.71
5.1
4.1
98.18
82.95
ng/l
0.87
98
538
755
6790
1.49
6.26
4.5
4.3
14.63
14.62
pmol/l
0.03
714
6295
53
252
2.17
6.25
1.2
1.2
—
—
—
0
0
858
7957
1.62
5.93
5.5
5.3
1.82
1.84
mu/l
0.22
820
7455
52
252
2.12
5.86
1.2
1.2
—
—
—
0
0
30
118
2.59
5.42
1.4
1.3
—
—
—
0
0
126
826
1.60
5.37
2.9
2.5
27.64
36.70
u/l
2.36
107
692
576
5004
1.37
5.32
11.0
9.2
4.02
4.05
e9/l
0.12
501
4382
512
4377
1.36
5.19
8.1
6.4
11.00
11.23
umol/l
0.18
492
4180
9
10
9.07
4.79
4.8
6.7
—
—
—
0
0
924
8824
1.81
4.63
13.7
11.2
25.10
26.17
u/l
1.38
910
8608
39
187
2.13
4.57
6.4
6.1
603.25
371.46
iu/ml
—
8
24
452
3859
1.32
4.34
2.5
2.5
74.86
75.08
nmol/l
0.06
420
3528
204
1542
1.41
4.33
3.6
3.8
339.58
349.43
ng/l
0.02
152
1093
468
4020
1.31
4.28
9.5
7.0
1.22
1.21
mmol/l
0.62
419
3505
701
6380
1.35
4.20
10.3
7.9
77.99
77.73
u/l
0.07
680
6060
846
7946
1.47
4.17
5.0
4.6
5.82
5.82
mmol/l
0.01
813
7390
361
3004
1.32
4.10
3.9
3.2
28.30
31.97
u/l
1.65
348
2849
954
9240
2.18
4.06
27.5
22.1
254.88
253.24
e9/l
0.34
946
9095
189
1426
1.40
4.04
3.1
2.8
0.69
0.89
e6/l
0.74
114
730
126
882
1.49
4.01
6.4
4.2
249.21
251.20
u/l
0.04
121
839
868
8207
1.50
4.00
4.9
4.7
4.63
4.64
mmol/l
0.13
839
7751
267
2133
1.35
4.00
6.0
3.9
93.27
91.53
%
0.54
261
2083
954
9245
2.16
3.96
27.4
22.1
4.53
4.52
e12/l
0.33
943
9080
15
48
3.16
3.94
1.9
2.9
—
—
—
0
0
876
8303
1.51
3.94
5.5
5.3
2.72
2.74
mmol/l
0.31
849
7816
102
691
1.53
3.79
12.1
7.6
9.71
8.89
mmol/l
0.58
96
667
864
8178
1.47
3.79
4.8
4.6
1.47
1.46
mmol/l
0.17
832
7685
32
154
2.11
3.76
1.2
1.1
—
—
—
0
0
46
257
1.83
3.56
3.0
2.8
—
—
—
0
0
88
588
1.55
3.50
1.4
1.7
—
—
—
0
0
414
3570
1.28
3.43
9.2
6.3
1.21
1.21
mmol/l
0.14
380
3302
882
8412
1.48
3.41
20.2
16.4
139.66
139.62
mmol/l
0.20
873
8246
41
226
1.85
3.33
1.2
1.3
—
—
—
0
0
80
533
1.55
3.23
3.0
3.1
218.71
176.70
ng/l
0.35
75
490
470
4137
1.26
3.22
3.2
2.8
—
—
estimate
—
0
0
548
4911
1.26
3.22
6.2
4.9
6.45
6.56
mmol/l
0.70
501
4599
10
24
4.20
3.20
3.3
3.0
0.62
0.61
mmol/l
—
10
24
68
438
1.59
3.18
1.4
1.4
223.24
244.24
miu/ml
0.21
41
213
821
7757
1.36
3.13
4.2
4.0
1.24
1.25
mmol/l
0.16
785
7246
154
1172
1.37
3.11
3.4
2.5
22.86
23.15
%
0.11
149
1101
881
8426
1.45
3.09
20.5
16.5
3.94
3.95
mmol/l
0.82
870
8240
109
783
1.44
3.07
4.7
3.7
1.69
1.83
mmol/l
0.18
98
665
663
6097
1.27
3.04
3.4
3.5
—
—
—
0
0
657
6039
1.27
3.01
3.6
3.3
41.31
43.11
u/l
0.31
638
5755
172
1341
1.34
2.98
3.1
2.9
2.02
2.61
e6/l
0.57
92
650
6
9
6.70
2.87
3.2
2.7
1.00
0.56
u/field
—
6
9
172
1349
1.33
2.86
2.0
1.9
—
—
—
0
0
173
1361
1.33
2.82
4.3
3.4
0.83
0.82
mmol/l
0.38
164
1300
254
2107
1.28
2.78
3.5
2.7
343.90
336.23
umol/l
0.54
231
1891
16
66
2.45
2.72
1.2
1.3
5.69
6.23
ug/l
0.22
16
56
116
862
1.39
2.72
8.1
6.7
—
—
—
0
0
258
2154
1.27
2.67
3.0
2.3
—
—
—
0
0
43
259
1.69
2.65
6.7
3.9
1.50
1.43
mg/l
0.31
38
231
102
750
1.40
2.55
8.7
9.1
116.75
121.27
g/l
1.34
97
736
15
62
2.44
2.55
1.2
1.1
5.98
6.32
umol/l
0.11
15
53
273
2308
1.25
2.53
3.6
3.1
0.23
0.43
e6/l
2.33
203
1665
89
640
1.43
2.52
1.7
1.5
—
—
—
0
0
132
1021
1.34
2.42
3.8
2.7
6.64
7.50
umol/l
0.41
113
895
270
2291
1.25
2.41
2.5
2.2
2.61
2.75
mg/l
0.47
238
1978
312
2691
1.23
2.40
3.8
3.2
47.17
84.86
e6/l
0.52
240
2035
325
2819
1.23
2.36
3.9
3.4
7.86
7.97
mmol/l
0.15
295
2417
172
1389
1.29
2.31
3.4
2.5
13.30
13.58
umol/l
0.21
163
1296
286
2454
1.23
2.29
2.3
2.1
160.58
244.31
u/l
1.18
271
2334
248
2096
1.25
2.28
3.9
3.7
1.02
1.02
kg/l
0.50
159
1385
212
1769
1.25
2.18
4.5
4.4
21.58
21.45
%
0.05
110
815
48
314
1.56
2.18
2.7
1.9
48.04
40.10
nmol/l
0.85
48
299
32
189
1.72
2.16
1.7
1.5
136.14
154.16
au/ml
—
7
51
5
10
5.02
2.07
1.0
1.0
—
—
—
0
0
5
10
5.02
2.07
1.0
1.0
—
—
—
0
0
51
343
1.51
2.06
1.7
1.4
—
—
—
0
0
64
454
1.44
1.99
1.9
1.6
—
—
—
0
0
115
899
1.32
1.98
8.0
8.5
5.04
5.09
kpa
0.27
107
868
21
112
1.89
1.97
2.0
1.3
—
—
—
0
0
115
900
1.31
1.97
8.0
8.5
12.45
12.41
kpa
0.03
107
871
26
149
1.77
1.96
1.5
1.2
2.75
5.30
u/ml
0.60
16
47
6
16
3.77
1.93
1.0
1.0
—
—
—
0
0
256
2207
1.22
1.93
5.5
5.4
2.08
2.41
ug/l
0.60
233
1987
189
1579
1.24
1.92
3.6
2.8
2.45
2.44
mmol/l
0.26
171
1417
40
260
1.56
1.89
1.2
1.3
—
—
—
0
0
799
7648
1.24
1.89
6.1
5.8
38.11
38.47
mmol/mol
0.62
766
7247
160
1317
1.26
1.85
3.1
3.1
0.70
0.75
ug/l
0.49
108
823
133
1071
1.28
1.85
10.0
5.8
1.07
1.05
mmol/l
0.59
125
998
113
891
1.30
1.84
8.2
8.5
0.10
0.87
mmol/l
1.57
91
734
833
8019
1.26
1.81
17.0
13.5
84.69
86.42
ml/min/173m2
1.48
774
7318
399
3604
1.18
1.78
15.2
12.6
1.20
1.21
inr
0.03
331
2999
5
135
0.37
1.76
3.4
6.0
288.00
366.57
umol/l
—
5
123
51
358
1.45
1.71
1.5
1.4
9.55
8.95
u/l
0.12
43
295
0
46
0.00
1.71
0.0
1.5
—
—
—
0
0
495
4562
1.17
1.71
3.6
3.2
87.99
103.97
ug/l
2.16
478
4308
84
643
1.34
1.70
2.4
2.6
67.16
70.28
ml/min/173m2
0.24
31
271
76
574
1.35
1.68
2.8
3.6
4.42
4.60
pmol/l
1.02
67
515
10
41
2.45
1.64
1.8
1.6
49.40
93.98
ng/l
—
10
41
25
150
1.68
1.64
1.6
1.3
2.06
7.86
u/ml
1.67
17
59
607
5697
1.17
1.63
4.8
4.5
18.40
1578.20
e6/l
—
5
79
21
120
1.77
1.63
1.1
1.2
—
—
—
0
0
663
6268
1.18
1.63
4.6
4.2
10.55
10.69
mm/h
0.10
633
5896
34
222
1.55
1.61
1.4
1.6
—
—
—
0
0
17
91
1.88
1.61
1.1
1.2
—
—
—
0
0
35
232
1.53
1.56
1.3
1.2
—
39.67
—
0
6
123
1004
1.26
1.55
2.0
1.8
—
—
—
0
0
69
522
1.35
1.53
10.9
9.8
1.12
1.33
%
1.30
69
517
38
258
1.49
1.52
1.3
1.4
330.53
302.78
ug/g
0.28
22
154
52
376
1.40
1.51
1.4
1.4
—
—
—
0
0
111
898
1.27
1.51
1.8
2.1
—
—
—
0
0
193
1662
1.20
1.47
1.6
1.5
—
—
—
0
0
43
303
1.44
1.45
2.3
2.0
—
—
—
0
0
117
958
1.25
1.45
2.0
1.9
—
—
—
0
0
5
16
3.14
1.44
1.8
2.9
—
—
—
0
0
70
538
1.32
1.41
1.3
1.4
—
—
—
0
0
84
663
1.29
1.40
1.3
1.3
189.20
231.10
u/ml
0.21
79
615
22
134
1.66
1.40
1.3
1.2
119.14
115.87
%
0.19
22
122
11
53
2.09
1.39
1.3
1.1
865.27
1566.09
miu/ml
2.11
11
53
502
4680
1.15
1.38
4.0
3.7
0.01
4.56
estimate
1.07
84
995
12
60
2.01
1.38
2.4
1.5
208.13
174.00
pmol/l
0.68
12
60
155
1316
1.21
1.37
2.4
2.5
121.09
113.76
ug/g
0.16
130
1047
5
17
2.95
1.36
1.0
1.2
1.19
1.17
mmol/l
—
5
17
0
38
0.00
1.34
0.0
1.6
—
—
—
0
0
23
144
1.61
1.33
1.3
1.4
476.71
341.29
mu/l
0.83
17
118
0
40
0.00
1.33
0.0
1.6
—
—
—
0
0
48
352
1.38
1.32
1.7
1.8
—
—
—
0
0
15
83
1.82
1.31
1.2
1.1
—
61.88
—
0
8
76
598
1.29
1.31
1.4
1.4
26.23
24.05
iu/l
0.23
66
515
504
4714
1.14
1.29
4.0
3.8
0.00
0.33
estimate
0.52
77
932
35
243
1.46
1.29
1.7
1.6
—
—
—
0
0
15
84
1.80
1.27
2.2
3.8
60.97
55.69
%
0.56
15
77
32
219
1.48
1.27
2.0
2.6
0.00
0.00
g/l
-0.00
27
196
389
3580
1.14
1.26
2.1
2.0
97.01
96.40
pmol/l
0.09
197
1938
26
171
1.53
1.24
1.7
1.4
—
—
—
0
0
32
221
1.46
1.22
1.3
1.3
249.57
244.00
u/ml
0.03
14
125
128
1080
1.21
1.22
2.0
2.2
—
—
—
0
0
5
19
2.64
1.21
1.2
1.3
—
—
—
0
0
78
623
1.27
1.21
2.3
2.4
11.57
18.41
au/ml
—
7
71
39
282
1.40
1.18
2.1
1.8
—
—
—
0
0
128
1087
1.20
1.15
2.0
1.9
3.58
3.49
ratio
0.35
98
826
493
4631
1.13
1.13
4.0
3.7
0.00
0.00
estimate
0.50
82
976
294
2674
1.14
1.12
3.5
2.6
56.92
61.78
u/l
0.91
276
2489
277
2512
1.14
1.10
4.7
4.2
12.60
8.69
mg/mmol
0.54
174
1595
24
160
1.51
1.10
1.7
1.5
—
—
—
0
0
72
578
1.27
1.09
2.8
2.3
10091.00
6370.74
u/l
0.28
32
251
30
211
1.44
1.07
1.3
1.2
—
6.37
—
0
15
10
52
1.93
1.06
1.4
1.3
—
25.71
—
0
7
7
33
2.13
1.05
2.4
1.4
—
—
—
0
0
54
423
1.29
1.01
1.6
1.5
—
—
—
0
0
74
603
1.25
1.01
3.0
3.0
66.41
66.98
g/l
0.27
66
564
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
7
35
2.01
1.00
1.3
1.2
128.14
118.51
%
—
7
35
13
76
1.72
0.99
2.4
2.4
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
0.04
11.94
u/ml
—
5
16
14
84
1.68
0.98
2.9
4.0
—
—
—
0
0
12
69
1.75
0.96
1.1
1.1
109.08
106.23
pmol/l
0.09
12
69
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
204
1835
1.14
0.92
3.3
2.6
3.74
6.76
e6/l
4.26
188
1668
16
102
1.58
0.91
1.9
1.5
—
—
—
0
0
29
211
1.39
0.89
1.3
1.2
—
—
—
0
0
240
2187
1.13
0.89
3.4
3.3
2533.14
1184.00
ng/l
1.23
215
1850
8
43
1.87
0.87
1.1
1.2
—
—
—
0
0
8
43
1.87
0.87
1.1
1.2
—
—
—
0
0
86
725
1.20
0.87
4.2
4.5
3.68
27.56
ug/l
1.38
67
597
242
2642
0.89
0.87
3.0
3.1
0.80
0.04
estimate
0.48
65
805
256
2346
1.12
0.86
1.7
1.6
20.06
20.30
nmol/l
0.09
234
2009
17
112
1.53
0.85
1.4
1.1
94.18
95.34
%
0.05
17
102
29
213
1.37
0.85
1.9
1.5
0.32
0.35
nmol/l
0.16
24
176
64
526
1.23
0.83
1.4
1.4
—
—
—
0
0
21
147
1.44
0.80
1.7
1.7
—
—
—
0
0
31
233
1.34
0.80
1.6
1.6
—
—
—
0
0
48
384
1.26
0.80
1.6
1.9
4.36
7.79
iu/ml
0.60
11
91
10
58
1.73
0.80
1.3
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
29
216
1.35
0.79
3.8
3.4
0.24
0.37
iu/ml
2.22
16
112
6
33
1.82
0.79
1.2
1.2
—
—
—
0
0
6
33
1.82
0.79
1.2
1.2
—
—
—
0
0
220
2009
1.12
0.79
1.9
1.7
1.25
1.11
mg/l
0.23
176
1528
14
90
1.56
0.78
1.2
1.8
—
—
—
0
0
21
149
1.42
0.76
1.3
1.1
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
72
609
1.20
0.73
2.8
2.5
9.28
6.75
ug/l
0.32
66
552
9
56
1.61
0.72
3.7
2.9
1827.44
1026.71
mg
—
9
56
28
366
0.76
0.72
1.1
1.1
1.53
1.54
g/l
0.07
28
366
7
40
1.76
0.71
1.1
1.1
—
—
—
0
0
9
57
1.58
0.71
1.1
1.5
0.49
0.51
e9/l
—
9
57
29
376
0.76
0.70
1.6
1.2
0.82
0.89
g/l
1.51
29
376
38
301
1.27
0.70
1.5
1.5
0.10
0.08
iu/ml
—
6
47
14
93
1.51
0.69
1.3
1.1
—
—
—
0
0
232
2143
1.11
0.68
1.8
1.7
—
—
—
0
0
304
2847
1.10
0.68
4.6
3.4
2.36
2.35
mmol/l
0.52
282
2604
27
205
1.33
0.67
1.6
1.5
—
—
—
0
0
23
171
1.35
0.66
5.3
3.3
42.44
33.20
umol/l
0.25
18
154
95
834
1.15
0.64
1.6
1.7
3.60
3.46
mmol/l
0.51
66
581
5
29
1.73
0.64
1.4
1.3
6.92
8.87
ug/l
—
5
29
56
470
1.20
0.63
5.3
8.0
23.68
24.35
mmol/l
0.64
51
449
131
1178
1.13
0.62
2.0
1.7
1.49
1.44
%
0.25
117
1053
23
173
1.34
0.62
1.3
1.6
—
—
—
0
0
8
50
1.60
0.61
1.0
1.2
—
—
—
0
0
19
139
1.37
0.60
1.0
1.1
—
1.11
—
0
7
16
221
0.72
0.60
1.0
1.1
1.16
1.80
u/ml
—
8
113
15
105
1.44
0.60
1.9
1.6
—
—
—
0
0
10
64
1.57
0.58
1.2
1.4
—
—
—
0
0
6
35
1.72
0.57
1.3
1.9
—
—
—
0
0
6
35
1.72
0.57
1.3
1.9
—
—
—
0
0
6
36
1.67
0.56
1.3
1.9
—
—
—
0
0
11
73
1.51
0.56
2.5
1.6
—
—
—
0
0
10
66
1.52
0.52
1.3
1.6
9.31
11.93
umol/l
—
10
61
10
66
1.52
0.52
1.1
1.4
81.00
77.36
umol/l
—
10
66
98
877
1.13
0.52
2.5
2.0
353.89
387.88
nmol/l
0.99
92
828
6
98
0.61
0.52
1.5
1.7
—
—
—
0
0
42
352
1.20
0.51
1.6
1.5
—
—
—
0
0
69
784
0.87
0.50
3.1
3.1
—
—
—
0
0
14
101
1.39
0.49
1.2
1.4
—
—
—
0
0
14
101
1.39
0.49
1.2
1.8
—
—
—
0
0
57
493
1.17
0.49
1.1
1.1
—
1.00
—
0
5
14
102
1.38
0.47
1.2
1.4
—
—
—
0
0
7
48
1.46
0.47
1.3
1.8
—
—
—
0
0
7
48
1.46
0.47
1.3
1.8
—
—
—
0
0
7
48
1.46
0.47
1.3
1.8
—
—
—
0
0
7
48
1.46
0.47
1.3
1.8
—
—
—
0
0
61
536
1.15
0.44
1.1
1.0
—
—
—
0
0
25
202
1.24
0.43
3.0
3.2
3.08
2.39
index
0.17
13
115
5
31
1.62
0.43
1.2
1.1
114.40
97.92
%
—
5
26
5
32
1.57
0.42
5.0
3.3
48.50
33.06
umol/l
—
5
23
26
213
1.23
0.41
4.0
3.5
1.10
2.51
ratio
2.25
12
126
11
79
1.40
0.41
1.9
1.7
—
—
—
0
0
34
288
1.19
0.39
1.6
1.6
58.73
56.61
ug/l
0.12
34
288
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
15
115
1.31
0.39
1.1
1.4
0.56
0.57
nmol/l
0.05
15
108
9
66
1.37
0.38
1.1
1.0
—
—
—
0
0
14
107
1.31
0.37
1.2
1.3
—
—
—
0
0
9
69
1.31
0.37
1.1
1.1
312.33
218.81
mg/l
—
9
58
6
43
1.40
0.35
4.8
3.8
811.50
613.86
u/ml
—
6
43
19
154
1.24
0.34
1.3
1.3
—
—
—
0
0
19
154
1.24
0.34
1.3
1.3
—
—
—
0
0
14
109
1.29
0.33
1.2
1.3
—
—
—
0
0
14
109
1.29
0.33
1.2
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
46
1.31
0.33
1.3
1.1
—
—
—
0
0
13
101
1.29
0.32
1.2
1.4
—
—
—
0
0
104
966
1.09
0.31
4.7
4.6
31.46
31.64
%
0.06
82
667
7
53
1.32
0.31
1.4
1.2
—
—
—
0
0
19
157
1.21
0.29
2.9
2.8
6.55
7.94
pmol/l
0.65
19
157
10
76
1.32
0.28
2.1
1.2
1.06
1.45
nmol/l
—
10
69
54
594
0.90
0.27
5.4
3.7
1.22
1.22
mmol/l
0.22
48
513
8
64
1.25
0.27
1.6
1.3
—
—
—
0
0
161
1692
0.94
0.27
2.8
2.4
—
—
—
0
0
22
187
1.18
0.26
1.3
1.6
—
—
—
0
0
5
74
0.67
0.26
1.0
1.3
—
—
—
0
0
5
75
0.66
0.26
1.0
1.3
—
—
—
0
0
69
746
0.92
0.25
1.3
1.3
62.02
145.80
u/ml
2.62
22
298
11
87
1.27
0.24
1.5
2.2
33.64
32.64
pg
0.36
11
87
243
2349
1.05
0.23
1.4
1.3
2.02
1.68
u/ml
0.15
70
654
5
41
1.22
0.22
1.6
3.4
0.30
1.27
%
—
5
41
5
42
1.19
0.21
1.0
1.5
—
—
—
0
0
5
42
1.19
0.21
1.0
1.5
—
—
—
0
0
21
182
1.16
0.21
1.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
10.02
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
15
177
0.85
0.21
1.8
1.9
—
—
—
0
0
26
230
1.13
0.20
1.2
1.2
—
—
—
0
0
36
397
0.90
0.20
3.5
3.3
1.02
1.02
ratio
0.21
31
371
261
2536
1.04
0.20
4.5
3.8
0.01
0.01
estimate
0.12
78
926
7
60
1.17
0.18
1.4
1.6
—
—
—
0
0
41
378
1.09
0.17
1.4
1.6
—
—
—
0
0
5
67
0.75
0.17
1.4
1.3
205.20
486.37
u/l
—
5
62
46
428
1.08
0.16
1.4
1.5
—
—
—
0
0
41
380
1.08
0.15
1.8
1.9
3.55
3.62
mg/l
0.03
29
273
6
77
0.78
0.15
1.0
1.0
—
—
—
0
0
6
77
0.78
0.15
1.0
1.1
—
—
—
0
0
6
77
0.78
0.15
1.0
1.1
—
—
—
0
0
10
83
1.21
0.15
1.2
1.6
—
—
—
0
0
10
83
1.21
0.15
1.2
1.6
—
—
—
0
0
10
83
1.21
0.15
1.2
1.6
—
—
—
0
0
42
451
0.93
0.15
1.5
1.6
0.30
0.31
mg/l
0.07
17
201
15
131
1.15
0.14
1.4
2.0
—
1885.71
—
0
7
340
3458
0.97
0.13
1.9
1.9
1.39
1.35
mmol/l
0.42
301
2959
22
199
1.11
0.13
1.6
2.1
4.48
5.00
umol/l
0.20
16
149
176
1716
1.03
0.12
1.3
1.3
39.97
29.19
iu/ml
0.39
49
512
5
45
1.11
0.10
1.6
1.1
—
—
—
0
0
5
46
1.09
0.09
1.8
2.6
46.60
46.88
umol/l
—
5
41
46
438
1.05
0.09
1.5
1.5
1.22
1.21
ratio
0.03
28
273
46
438
1.05
0.09
1.5
1.5
0.91
0.96
ratio
0.52
28
273
46
438
1.05
0.09
1.5
1.5
1.50
1.16
ratio
0.98
28
273
13
116
1.12
0.09
1.1
1.0
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
19
206
0.92
0.08
1.2
1.6
35837.45
14145.00
e6/l
0.37
11
149
153
1562
0.98
0.08
2.5
2.2
—
—
—
0
0
24
256
0.94
0.08
1.1
1.1
0.43
2.59
u/ml
3.10
12
140
351
3546
0.98
0.07
3.9
3.6
0.46
0.02
estimate
0.61
67
824
7
85
0.82
0.07
1.0
1.1
—
—
—
0
0
24
255
0.94
0.07
3.6
4.3
1.78
1.37
mmol/l
0.46
24
249
18
167
1.08
0.07
1.4
1.5
—
—
—
0
0
162
1644
0.98
0.06
1.5
1.7
46207352.88
29757221.99
pmol/l
0.14
145
1398
161
1587
1.02
0.05
1.3
1.3
19.78
10.74
u/ml
0.56
69
626
10
91
1.10
0.04
1.3
1.6
—
—
—
0
0
35
338
1.04
0.04
1.7
1.7
—
—
—
0
0
124
1225
1.01
0.03
1.7
1.7
1242.55
1160.51
nmol/l
0.38
91
940
16
169
0.95
0.03
1.2
1.3
—
—
—
0
0
299
3007
0.99
0.03
4.0
3.6
52.49
52.90
ng/l
0.01
183
1956
20
209
0.96
0.03
1.4
1.4
—
—
—
0
0
82
814
1.01
0.00
1.6
1.6
1212.82
1005.55
mu/l
0.50
71
691
14
138
1.01
0.00
1.1
1.6
—
—
—
0
0
29
292
0.99
0.00
1.2
1.3
—
—
—
0
0
36
358
1.01
0.00
1.7
1.7
3.95
8.33
u/ml
—
8
82
39
388
1.01
0.00
1.7
1.9
—
—
—
0
0
47
472
1.00
0.00
1.4
1.5
71.12
61.62
ug/l
0.51
39
401
206
2058
1.00
0.00
1.7
1.5
2.08
2.29
g/l
1.39
131
1312
45
447
1.01
0.00
4.7
3.7
1.28
1.78
mmol/l
0.35
38
327
18
175
1.03
0.00
2.1
2.4
46.82
109.37
ug/min
1.16
11
110
7
79
0.89
0.00
1.0
1.1
—
—
—
0
0
7
79
0.89
0.00
1.0
1.1
—
—
—
0
0
9
99
0.91
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
24.50
—
0
5
5
49
1.02
-0.00
2.8
3.6
0.60
0.86
index
—
5
49
9
93
0.97
-0.00
1.1
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
3.0
1.6
0.00
1.85
u/field
—
5
38
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
88
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
93
0.97
-0.00
1.0
1.1
—
—
—
0
0
9
94
0.96
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.1
1.13
1.06
ratio
—
5
42
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_SCALPNECK and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_SCALPNECK | 0.786 [0.65, 0.95] | 0.011 |
| Birth year | 0.992 [0.98, 1.0] | 0.06 |
During the follow-up period (1.1.1998 — 31.12.2019), 169 out of 3036 females with CD2_BENIGN_MELANOCYTIC_SCALPNECK died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_SCALPNECK | 1.089 [0.92, 1.3] | 0.336 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 295 out of 2431 males with CD2_BENIGN_MELANOCYTIC_SCALPNECK died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_SCALPNECK.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.068% | 0.168% |
| 5 | 0.421% | 1.092% |
| 10 | 1.019% | 2.71% |
| 15 | 1.971% | 5.418% |
| 20 | 3.539% | 9.434% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_SCALPNECK – Melanocytic naevi of scalp and neck
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data