retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.
Other, unspecified and serous retinal detachments
DOID EFO Endpoint Browser PheWeb
H7_RETINALDETACHOTH
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1387 |
4. Check minimum number of eventsNone |
1387 |
5. Include endpointsNone |
1387 |
6. Filter based on genotype QC (FinnGen only) |
1257 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other, unspecified and serous retinal detachments
based on the number of shared cases.
Similar with more cases:
- Retinal detachments and breaks
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9905 | 4592 | 5209 |
| Only index persons | 7811 | 3666 | 4145 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.13 | 0.15 |
| Only index persons | 0.15 | 0.13 | 0.16 |
| Median age at first event (years) | |||
| Whole population | 59.61 | 61.44 | 58.09 |
| Only index persons | 58.28 | 60.41 | 56.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1257 | 577 | 680 |
| Unadjusted period prevalence (%) | 0.26 | 0.20 | 0.31 |
| Median age at first event (years) | 59.99 | 59.69 | 60.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1281
- Matched controls
- 12810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
154.7
307.7
229
18
CKC12
NOMESCO Finland
Photocoagulation of retina
256.0
307.7
248
12
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
307.7
316
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
192.7
307.7
196
12
H33.0
ICD-10 Finland
Retinal detachment with retinal break
9834.8
307.7
575
*
H33.5
ICD-10 Finland
Other retinal detachments
1784.8
307.7
746
10
WX140
NOMESCO Finland
Parabulbar anesthesy
45.8
307.7
352
105
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
11.5
283.5
338
387
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
251.6
233
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
1303.0
229.4
217
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
9.1
226.4
322
456
H43.1
ICD-10 Finland
Vitreous haemorrhage
34.2
214.1
138
45
Z96.1
ICD-10 Finland
Presence of intraocular lens
6.5
203.0
427
912
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
744.5
198.9
191
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
536.2
190.6
185
*
S01ED51
ATC
timolol, combinations; ophthalmic
7.8
181.0
288
458
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.0
178.5
750
2830
H26.4
ICD-10 Finland
After-cataract
6.5
160.4
313
611
CJB10
NOMESCO Finland
Laser discission of secondary cataract
7.0
153.3
269
471
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
54.8
152.6
87
17
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
144.6
136
*
H26.2
ICD-10 Finland
Complicated cataract
27.6
131.0
90
35
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.9
127.8
673
2817
H43.8
ICD-10 Finland
Other disorders of vitreous body
5.5
127.0
287
634
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
36.3
114.5
72
21
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.2
112.8
161
222
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
112.2
106
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.0
103.5
379
1210
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
102.5
97
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
40.7
101.7
62
16
XCH00
NOMESCO Finland
Eye pressure measurement
7.6
99.8
151
222
S01EC01
ATC
acetazolamide; systemic
12.7
98.0
98
83
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
265.0
97.1
98
*
S01ED01
ATC
timolol; ophthalmic
8.3
93.1
129
171
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
89.6
85
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
88.6
84
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
15.0
86.7
78
55
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
828.2
80.3
78
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
103.6
80.0
87
9
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
163.7
73.9
77
5
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
72.6
69
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
693.4
67.6
66
*
S01EA03
ATC
apraclonidine; ophthalmic
20.8
65.5
50
25
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
93.9
64.6
71
8
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
64.1
61
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
224.3
62.7
64
*
37601
ICD-8 Finland
Detachment of retina, Secundaria
+∞
62.0
59
*
XCK10
NOMESCO Finland
Photography of fundus of eye
4.2
61.5
183
491
S01EA05
ATC
brimonidine; ophthalmic
7.8
59.5
85
116
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
58.8
56
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.6
57.6
486
2412
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
13.6
53.9
51
39
H26.02
ICD-10 Finland
Presenil cataract
6.8
50.3
81
126
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
47.2
45
*
S01EE01
ATC
latanoprost; ophthalmic
4.0
46.4
144
396
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.0
45.5
242
933
114
Kela drug reimbursment
Glaucoma
3.3
41.7
180
613
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
39.9
619
3852
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.1
38.5
44
45
XCK00
NOMESCO Finland
Perimetry
4.0
38.2
113
299
S01BC03
ATC
diclofenac; ophthalmic
6.8
37.2
59
90
ZXA00
NOMESCO Finland
Right side
2.2
36.3
416
2277
S01BC05
ATC
ketorolac; ophthalmic
4.6
36.0
89
205
H3603, E103,
ICD-10 Finland
+∞
35.6
34
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
35.6
34
*
WX002
NOMESCO Finland
Sedation and analgesia
2.4
35.4
310
1514
H35.4
ICD-10 Finland
Peripheral retinal degeneration
126.9
34.9
37
*
A10AA01, ,
ATC
8.1
34.7
47
60
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
52.9
34.6
41
8
H53.1
ICD-10 Finland
Subjective visual disturbances
3.4
34.5
134
426
3745
FHL
Hard membrane girding, cerclage with coagulation
346.0
34.1
34
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.4
33.5
86
204
3643
FHL
Vitrectomy through pars Plana
335.4
33.0
33
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
36.1
32.9
42
12
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.3
32.1
55
91
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
31.4
30
*
A10AB01
ATC
insulin (human); parenteral
5.9
30.9
56
98
A10AA02, ,
ATC
6.0
30.7
55
95
H52.1
ICD-10 Finland
Myopia
4.9
30.7
69
147
S01EC04
ATC
brinzolamide; ophthalmic
4.1
30.5
87
224
3618X
ICD-9 Finland
Retinal detachments and defects, Other forms of retinal detachment
+∞
30.3
29
*
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
30.3
29
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
29.3
28
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.3
29.2
60
118
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
298.5
28.9
29
*
ZXA05
NOMESCO Finland
Left side
2.1
28.9
369
2078
3619X
ICD-9 Finland
Retinal detachments and defects, Unspecified retinal detachment
+∞
28.2
27
*
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
28.2
27
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
7.7
27.7
39
52
XCW10
NOMESCO Finland
Assessment of vision
7.6
27.2
39
53
H34.8
ICD-10 Finland
Other retinal vascular occlusions
76.9
26.9
30
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
276.6
26.8
27
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.0
26.2
76
198
37609
ICD-8 Finland
Detachment of retina, Unspecified
+∞
26.1
25
*
H35.37
ICD-10 Finland
Macular holes
265.8
25.8
26
*
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
6.9
25.2
39
58
XCD20
NOMESCO Finland
Photoangiography of eye
39.7
25.0
31
8
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
91.9
24.7
27
*
S01EC03
ATC
dorzolamide; ophthalmic
6.4
24.1
40
64
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
24.0
23
*
T89
ICPC
Diabetes insulin dependent
4.5
22.9
57
132
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
85.0
22.7
25
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
234.0
22.7
23
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.1
22.4
63
160
ZXA10
NOMESCO Finland
Bilateral
2.1
22.1
254
1360
H57.1
ICD-10 Finland
Ocular pain
3.8
22.0
69
190
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
21.9
21
*
37603
ICD-8 Finland
Detachment of retina, Retinoschisis
+∞
21.9
21
*
H40.0
ICD-10 Finland
Glaucoma suspect
2.7
21.3
126
505
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.1
21.3
32
46
H3603, E113,
ICD-10 Finland
+∞
20.9
20
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.5
20.8
30
41
H35.36
ICD-10 Finland
Macular cyst
213.3
20.6
21
*
CKA10
NOMESCO Finland
Biopsy of vitreous body
111.9
20.6
22
*
H27.0
ICD-10 Finland
Aphakia
30.6
20.6
27
9
H25.8
ICD-10 Finland
Other senile cataract
2.3
19.7
164
769
S01FA01
ATC
atropine; ophthalmic
29.4
19.7
26
9
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.3
19.0
38
73
H3600, E113,
ICD-10 Finland
+∞
18.8
18
*
H3601, E113,
ICD-10 Finland
+∞
18.8
18
*
H54.4
ICD-10 Finland
Blindness, monocular
30.5
18.4
24
8
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
17.9
18.3
28
16
CKC15
NOMESCO Finland
Panretinal photocoagulation
67.6
17.8
20
*
H3601, E103,
ICD-10 Finland
+∞
17.7
17
*
A10AB05
ATC
insulin aspart; parenteral
2.6
17.3
105
426
H20.1
ICD-10 Finland
Chronic iridocyclitis
12.8
17.2
30
24
A10AC01
ATC
insulin (human); parenteral
2.6
16.9
100
401
H33
ICD-10 Finland
Retinal detachments and breaks
35.5
16.7
21
6
H35.8
ICD-10 Finland
Other specified retinal disorders
172.2
16.5
17
*
H43.3
ICD-10 Finland
Other vitreous opacities
5.3
16.3
33
64
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
16.2
125
566
H53.4
ICD-10 Finland
Visual field defects
4.1
15.8
43
107
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
33.8
15.8
20
6
37002
ICD-8 Finland
Refractive errors, Myopia
33.8
15.8
20
6
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
15.7
15
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
16.3
15.3
24
15
3661A
ICD-9 Finland
Cataract, Senile cataract
6.2
15.2
26
43
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
15.1
456
3227
S01EE03
ATC
bimatoprost; ophthalmic
3.9
14.9
44
116
H36.00
ICD-10 Finland
Diabetic background retinopathy
57.4
14.8
17
*
H3600, E103,
ICD-10 Finland
+∞
14.6
14
*
ZXD05
NOMESCO Finland
Urgent procedure
1.7
14.6
382
2601
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
14.6
352
2346
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
81.1
14.6
16
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
81.1
14.6
16
*
A10AE05
ATC
insulin detemir; parenteral
2.8
14.2
72
266
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.7
14.0
75
286
S01EE05
ATC
tafluprost; ophthalmic
3.0
13.9
62
214
H36.01
ICD-10 Finland
Diabetic maculopathy
53.9
13.8
16
*
H44.0
ICD-10 Finland
Purulent endophthalmitis
53.9
13.8
16
*
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
+∞
13.6
13
*
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
+∞
13.6
13
*
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
13.6
13
*
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
11.1
13.5
25
23
H34.2
ICD-10 Finland
Other retinal artery occlusions
141.4
13.5
14
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
6.1
13.4
23
38
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
18.4
13.4
20
11
H54.1
ICD-10 Finland
Severe visual impairment, binocular
40.5
13.2
16
*
F05
ICPC
Visual disturbance other
3.2
13.2
53
172
H54.0
ICD-10 Finland
Blindness, binocular
50.5
12.9
15
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
17.5
12.5
19
11
S01EX03, ,
ATC
3.9
12.5
37
98
F29
ICPC
Eye symptom/complaint other
2.0
12.3
139
731
A10AB04
ATC
insulin lispro; parenteral
3.8
12.2
37
100
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
5.7
12.0
22
39
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
13.5
12.0
20
15
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.5
11.9
40
116
H04AA01
ATC
glucagon; nasal, parenteral
5.6
11.7
22
40
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
30.3
11.7
15
5
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
30.3
11.7
15
5
H44.2
ICD-10 Finland
Degenerative myopia
65.6
11.6
13
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
23.1
11.6
16
7
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
5.3
11.6
23
44
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
11.5
149
822
37403
ICD-8 Finland
Cataract, Complicata
+∞
11.5
11
*
3649
FHL
Other measure in this category
+∞
11.5
11
*
CKD25
NOMESCO Finland
External drainage of subretinal fluid
+∞
11.5
11
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
11.5
11
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
11.3
113
568
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.3
11.3
83
368
S01BA01
ATC
dexamethasone; ophthalmic
2.8
11.3
56
205
A10AE04
ATC
insulin glargine; parenteral
2.0
11.1
121
629
A10AD01
ATC
insulin (human); parenteral
4.9
11.0
24
50
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
43.7
10.9
13
*
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.5
10.8
36
104
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
60.5
10.6
12
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
60.5
10.6
12
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
11.3
10.6
19
17
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
10.5
83
380
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
10.4
10
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.1
10.4
97
475
WZC30
NOMESCO Finland
Teaching
1.7
10.4
216
1371
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
19.0
10.3
15
8
H44.5
ICD-10 Finland
Degenerated conditions of globe
20.2
9.8
14
7
H54.7
ICD-10 Finland
Unspecified visual loss
8.8
9.8
20
23
A10AE06
ATC
insulin degludec; parenteral
2.9
9.6
44
155
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.9
9.4
27
70
37520
ICD-8 Finland
Glaucoma, Secondary
100.8
9.4
10
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
100.8
9.4
10
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
100.8
9.4
10
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
9.4
9
*
3759
FHL
Other measure in this category
+∞
9.4
9
*
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
21.9
9.4
13
6
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
9.3
285
1984
H16.0
ICD-10 Finland
Corneal ulcer
2.3
9.3
68
302
H44.1
ICD-10 Finland
Other endophthalmitis
37.0
9.0
11
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
24.2
8.9
12
5
S01BA04
ATC
prednisolone; ophthalmic
3.3
8.8
33
103
S01AX11
ATC
[U] ofloxacin
2.6
8.6
47
182
H21.0
ICD-10 Finland
Hyphaema
11.7
8.6
15
13
H27.1
ICD-10 Finland
Dislocation of lens
11.7
8.6
15
13
H35.9
ICD-10 Finland
Retinal disorder, unspecified
20.2
8.5
12
6
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
90.6
8.4
9
*
H3603, E106,
ICD-10 Finland
+∞
8.3
8
*
3742
FHL
Cryocoagulation under general anesthesia
+∞
8.3
8
*
3852
FHL
Reoperation for another reason
+∞
8.3
8
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
8.3
8
*
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
+∞
8.3
8
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
8.3
95
503
S01EE04
ATC
travoprost; ophthalmic
3.3
8.2
30
92
Z3231
NOMESCO Finland
Registered nurse
1.5
8.2
318
2325
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
8.2
162
1013
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
17.3
8.1
12
7
S01EB01
ATC
pilocarpine; ophthalmic
7.3
8.0
18
25
ZXE00
NOMESCO Finland
One hour or less
1.4
7.9
444
3478
37405
ICD-8 Finland
Cataract, Traumatica
15.1
7.7
12
8
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.6
436
3420
TCG10
NOMESCO Finland
Removal of sutures from cornea
8.1
7.6
16
20
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
25.2
7.6
10
*
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.4
7.5
26
77
ZX198
NOMESCO Finland
Other local administration
7.2
7.5
17
24
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
7.7
7.4
16
21
D01
ICPC
Abdominal pain/cramps general
1.7
7.4
135
826
H26.1
ICD-10 Finland
Traumatic cataract
10.9
7.3
13
12
3626A
ICD-9 Finland
Other retinal disorders, Peripheral retinal degenerations
+∞
7.3
7
*
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
7.3
7
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.4
7.3
49
210
J01DB01
ATC
cefalexin; oral
1.5
7.2
983
8895
S01BA07
ATC
fluorometholone; ophthalmic
3.6
7.2
23
65
H25.0
ICD-10 Finland
Senile incipient cataract
2.0
7.2
78
406
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
30.2
7.2
9
*
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
20.1
7.1
10
5
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
20.1
7.1
10
5
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
20.1
7.1
10
5
37402
ICD-8 Finland
Cataract, Senilis
12.1
7.1
12
10
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.1
7.1
18
30
N02BE01
ATC
paracetamol; systemic, rectal
1.6
7.1
1097
10159
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
8.8
7.1
14
16
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
7.0
100
569
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
7.0
40
159
SFA10
NOMESCO Finland
One-surface restoration
1.4
6.9
607
5091
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.5
6.9
41
166
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.3
6.8
17
40
37404
ICD-8 Finland
Cataract, Secundaria
40.3
6.8
8
*
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
40.3
6.8
8
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.7
121
738
CFB00
NOMESCO Finland
Suture of conjunctiva
22.6
6.7
9
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.6
196
1348
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
12.3
6.6
11
9
Z94.0
ICD-10 Finland
Kidney transplant status
4.2
6.6
17
41
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
10.1
6.5
12
12
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
1.9
6.5
87
485
C10AA05
ATC
atorvastatin; oral
1.4
6.5
534
4418
CHC05
NOMESCO Finland
Iridotomy
3.4
6.4
22
65
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
70.2
6.4
7
*
Q14.10
ICD-10 Finland
Congenital retinoschis
70.2
6.4
7
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.9
6.3
80
438
37711
ICD-8 Finland
Other diseases of retina and optic nerve, Degeneratio retinae
+∞
6.3
6
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
6.3
6
*
CKD75
NOMESCO Finland
Retinotomy
+∞
6.3
6
*
H31.0
ICD-10 Finland
Chorioretinal scars
+∞
6.3
6
*
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
6.3
6
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
6.3
6
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
6.3
6
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
+∞
6.3
6
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
6.3
6
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
6.3
6
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
6.3
6
*
A02BC02
ATC
pantoprazole; systemic
1.4
6.2
822
7287
3639
FHL
Other measure in this category
26.8
6.2
8
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
6.2
51
239
H43.9
ICD-10 Finland
Disorder of vitreous body, unspecified
4.0
6.2
17
43
H02AB06
ATC
prednisolone; systemic
1.3
6.1
555
4647
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.0
803
7110
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.0
387
3072
S01FA04
ATC
cyclopentolate; ophthalmic
3.5
6.0
20
58
V03AE01
ATC
polystyrene sulfonate; oral
3.4
6.0
21
63
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
796
6784
1.46
9.40
6.3
5.3
7.00
6.70
mmol/l
2.92
765
6493
667
5571
1.41
8.35
20.0
16.1
1.32
1.28
inr
0.91
568
4653
915
8110
1.45
8.03
5.3
4.4
13.86
12.81
mm/h
1.07
859
7572
1134
10520
1.68
8.02
22.5
17.4
22.94
25.91
mg/l
2.37
972
8799
39
144
2.76
7.82
1.1
1.1
—
—
—
0
0
715
6086
1.40
7.78
7.8
6.8
12.26
11.93
umol/l
0.22
676
5840
745
6408
1.39
7.48
11.0
9.8
4.33
4.16
e9/l
0.94
660
5573
691
5880
1.38
7.35
10.0
7.5
1.21
1.21
mmol/l
1.03
603
5073
261
1875
1.49
7.22
3.7
2.7
2.18
2.28
g/l
2.28
247
1734
39
155
2.56
6.81
1.3
1.2
2.24
2.94
u/ml
0.38
17
50
950
8575
1.42
6.78
10.3
8.5
81.12
80.15
u/l
0.21
894
8154
614
5181
1.36
6.61
6.1
5.3
35.22
35.28
g/l
0.09
576
4879
1158
10894
1.66
6.59
26.7
20.8
139.56
139.66
mmol/l
0.71
1145
10691
1158
10909
1.64
6.37
27.0
21.0
4.00
3.99
mmol/l
0.89
1144
10689
36
148
2.47
5.90
1.3
1.2
2.95
6.61
u/ml
0.93
20
62
166
1131
1.54
5.85
3.1
2.8
72.77
69.55
e9/l
0.50
122
838
205
1464
1.48
5.77
6.4
4.6
242.81
251.39
u/l
0.40
190
1385
480
3960
1.34
5.77
4.7
4.0
14.75
8.38
mg/mmol
1.35
328
2508
466
3834
1.34
5.68
4.1
3.5
41.02
83.78
e6/l
1.15
380
2971
30
115
2.65
5.67
1.1
1.3
—
—
—
0
0
237
1746
1.44
5.67
4.0
2.7
23.75
22.82
%
0.48
227
1629
266
2001
1.42
5.67
3.8
2.7
12.86
12.84
umol/l
0.02
251
1865
619
5311
1.32
5.61
9.0
6.9
1.21
1.21
mmol/l
0.38
585
4919
86
502
1.76
5.58
2.2
2.7
4.24
4.18
g/l
0.28
80
463
86
502
1.76
5.58
2.2
2.7
7.59
7.41
g/l
0.44
80
463
22
72
3.09
5.51
1.0
1.2
—
—
—
0
0
1180
11232
1.64
5.43
29.0
22.8
85.44
80.37
umol/l
2.52
1168
11102
77
439
1.80
5.41
2.2
2.9
1.21
1.15
g/l
0.04
69
384
449
3696
1.33
5.39
2.8
2.2
254.85
222.52
u/l
0.27
425
3507
535
4522
1.31
5.31
4.8
4.1
88.56
78.96
ng/l
0.10
399
3350
85
502
1.74
5.30
2.2
2.7
3.74
3.69
g/l
0.14
80
463
1112
10459
1.48
5.28
5.8
5.3
4.52
4.57
mmol/l
0.81
1046
9750
251
1892
1.41
5.26
2.3
2.1
29.84
29.62
s
0.24
241
1838
162
1129
1.50
5.13
11.6
7.6
11.16
10.34
mmol/l
0.70
157
1082
68
380
1.83
5.11
2.0
2.8
0.00
0.02
g/l
0.89
62
344
1106
10410
1.46
5.05
5.7
5.1
1.43
1.44
mmol/l
0.45
1035
9645
336
2681
1.34
4.91
3.0
2.8
4.74
5.29
e6/l
0.36
309
2458
677
5946
1.29
4.90
4.4
4.0
0.00
0.26
estimate
0.52
137
1202
1088
10224
1.43
4.88
21.3
16.9
76.94
78.51
ml/min/173m2
1.74
1028
9533
402
3300
1.32
4.82
4.0
3.4
0.67
0.43
e6/l
0.65
318
2451
453
3785
1.30
4.76
3.6
3.3
31.52
38.30
u/l
0.90
421
3574
1124
10636
1.46
4.75
6.6
6.0
2.60
2.66
mmol/l
1.27
1052
9868
519
4420
1.29
4.71
4.0
3.9
0.09
0.05
estimate
0.33
117
1032
18
58
3.13
4.65
2.1
3.1
976.33
1068.47
u/ml
0.10
18
58
1165
11112
1.53
4.64
15.1
12.5
25.88
26.65
u/l
0.79
1131
10798
77
467
1.69
4.41
2.2
2.7
2.81
2.99
g/l
0.79
71
428
662
5848
1.27
4.38
4.3
3.9
0.01
0.00
estimate
0.42
144
1250
97
626
1.59
4.36
1.4
1.5
—
—
—
0
0
941
8694
1.31
4.33
27.0
21.4
13.73
13.72
%
0.10
936
8576
78
478
1.67
4.30
1.6
2.1
42.06
39.03
u/l
0.56
70
427
433
3637
1.29
4.27
3.1
2.6
61.14
84.23
u/l
0.52
401
3388
1042
9776
1.35
4.25
5.8
5.2
1.90
1.97
mu/l
1.04
968
8998
144
1020
1.46
4.22
2.4
2.4
0.31
0.52
e6/l
0.82
133
975
146
1037
1.46
4.22
2.7
3.0
67.11
66.53
g/l
0.40
136
965
1187
11400
1.56
4.21
33.3
26.2
244.15
245.55
e9/l
0.30
1171
11162
668
5924
1.27
4.21
4.3
4.0
8.73
2.64
estimate
0.30
152
1278
1187
11401
1.56
4.20
33.1
26.1
91.50
91.46
fl
0.15
1178
11274
1187
11403
1.56
4.17
33.9
26.8
40.08
40.27
%
0.56
1179
11268
1187
11403
1.56
4.17
33.3
26.3
6.86
6.77
e9/l
0.37
1166
11132
1187
11403
1.56
4.17
33.2
26.2
4.45
4.47
e12/l
0.62
1166
11135
1076
10153
1.37
4.17
7.7
6.5
41.13
39.41
mmol/mol
6.38
1024
9485
1187
11405
1.56
4.14
33.5
26.4
134.54
135.05
g/l
0.55
1180
11276
602
5283
1.26
4.11
3.5
2.9
—
—
estimate
—
0
0
472
4024
1.27
4.10
4.0
3.3
7.32
7.76
mmol/l
1.34
414
3408
168
1233
1.42
4.07
5.4
3.6
1.80
1.96
mmol/l
0.26
155
1055
173
1278
1.41
4.04
5.3
3.6
5.83
5.84
kpa
0.05
168
1237
72
442
1.67
3.97
2.0
2.7
11.01
10.68
g/l
0.22
65
400
1058
9980
1.35
3.92
4.9
4.4
1.31
1.31
mmol/l
0.03
982
9161
885
8160
1.27
3.85
4.6
4.2
14.95
14.88
pmol/l
0.39
810
7486
258
2052
1.32
3.77
3.5
3.1
1.05
0.98
e6/l
0.15
162
1114
372
3108
1.28
3.75
3.3
3.5
0.03
0.04
estimate
0.13
111
981
211
1631
1.35
3.74
9.0
6.0
1.06
1.03
mmol/l
1.11
200
1504
136
981
1.43
3.64
3.6
3.1
184.79
219.32
ng/l
0.55
126
915
101
687
1.51
3.63
3.7
2.8
1.15
1.19
%
0.18
101
681
99
678
1.50
3.46
3.8
2.8
0.63
0.62
%
0.06
99
673
44
245
1.82
3.43
2.3
2.3
249.67
111.02
ug/min
0.55
27
146
351
2941
1.27
3.41
4.7
4.2
85.76
88.04
%
0.87
337
2884
237
1888
1.31
3.41
3.8
3.3
2.94
2.09
e6/l
0.68
138
950
564
4985
1.23
3.40
2.8
2.4
78.41
77.92
nmol/l
0.15
515
4490
12
33
3.66
3.29
1.3
1.0
—
—
—
0
0
62
386
1.64
3.28
1.4
1.3
—
—
—
0
0
244
1964
1.30
3.25
1.3
1.3
30.35
32.98
iu/ml
0.13
81
607
60
372
1.64
3.23
2.1
2.8
0.00
0.00
g/l
-0.00
54
328
43
244
1.79
3.18
7.4
6.2
414.00
423.50
iu/ml
—
8
30
281
2311
1.28
3.16
4.3
4.1
428.92
433.40
ng/l
0.01
225
1886
47
275
1.74
3.14
1.6
1.5
—
—
—
0
0
17
67
2.56
3.13
2.6
3.1
325.00
222.02
e6/l
0.78
12
60
175
1354
1.34
3.08
8.4
8.3
95.16
95.39
%
0.15
167
1311
57
355
1.63
3.03
4.1
3.4
1.62
1.67
mg/l
0.19
52
325
248
2021
1.28
2.99
1.8
1.7
1180.13
1180.92
nmol/l
0.00
202
1536
190
1497
1.32
2.96
8.1
8.1
5.05
5.13
kpa
0.57
183
1444
199
1579
1.31
2.94
2.0
1.9
—
—
—
0
0
190
1498
1.32
2.94
8.1
8.1
12.97
12.02
kpa
1.19
184
1447
360
3077
1.24
2.88
3.2
2.9
356.84
351.66
umol/l
0.44
326
2726
553
4937
1.21
2.88
3.8
3.1
142.61
150.23
ug/l
0.29
517
4585
26
129
2.04
2.87
1.8
1.3
0.15
0.19
nmol/l
1.82
21
103
87
606
1.47
2.84
1.9
1.8
1.49
1.60
g/l
0.51
82
527
159
1230
1.33
2.81
3.4
3.6
—
—
—
0
0
26
131
2.01
2.76
1.4
1.3
49.50
86.77
u/ml
—
6
7
187
1489
1.30
2.70
8.2
8.1
0.55
0.87
mmol/l
0.63
161
1221
1080
10343
1.28
2.67
5.8
5.3
6.15
5.99
mmol/l
2.74
1000
9478
252
2087
1.26
2.66
2.2
2.0
—
—
—
0
0
19
86
2.23
2.64
1.1
1.1
101.11
109.90
pmol/l
0.42
19
86
10
30
3.35
2.60
1.0
1.1
81.40
85.58
%
—
5
19
11
36
3.07
2.56
1.0
1.2
—
—
—
0
0
16
68
2.37
2.56
2.6
2.9
687.70
614.72
e6/l
—
10
58
120
906
1.36
2.51
6.9
4.0
111.02
93.23
ng/l
1.07
101
782
18
82
2.21
2.48
2.2
2.2
776.08
633.17
ml
0.29
12
53
654
5993
1.19
2.41
2.8
2.7
—
—
—
0
0
916
8650
1.21
2.40
28.5
22.5
331.70
332.34
g/l
1.38
911
8601
780
7260
1.19
2.40
5.6
4.8
2.83
1632.91
e6/l
—
6
114
574
5207
1.19
2.37
2.3
2.2
96.73
94.71
pmol/l
0.44
309
2783
23
118
1.97
2.36
1.3
1.2
7.28
7.55
mmol/l
0.19
17
101
11
40
2.76
2.27
1.1
1.1
102.18
94.68
%
0.28
11
31
95
704
1.38
2.25
4.9
3.6
2.16
2.03
mmol/l
0.16
64
516
5
9
5.57
2.21
1.0
1.0
—
—
—
0
0
17
80
2.14
2.19
1.4
1.1
—
—
—
0
0
52
348
1.52
2.12
1.4
1.4
0.28
20.78
iu/ml
0.49
18
58
18
89
2.04
2.06
1.3
1.1
—
—
—
0
0
303
2625
1.20
2.06
4.3
4.1
1.02
1.02
kg/l
0.46
210
1764
22
118
1.88
2.02
1.4
1.4
—
—
—
0
0
17
83
2.06
2.01
1.4
1.1
—
—
—
0
0
17
83
2.06
2.01
1.4
1.1
—
—
—
0
0
19
97
1.97
2.00
1.3
1.1
—
—
—
0
0
46
304
1.53
2.00
1.5
1.6
—
—
—
0
0
419
3746
1.18
1.98
4.2
3.3
1995.17
1418.56
ng/l
1.37
372
3233
62
437
1.44
1.98
4.2
2.8
24.22
24.73
mmol/l
0.47
62
432
50
338
1.50
1.96
1.7
1.8
—
—
—
0
0
34
211
1.63
1.93
4.7
1.4
0.84
0.88
nmol/l
0.13
29
180
58
406
1.45
1.92
1.4
1.2
0.75
1.18
u/ml
0.23
12
26
180
1493
1.24
1.89
1.9
1.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
60
426
1.43
1.86
4.6
2.6
0.33
0.37
iu/ml
0.46
36
228
345
3050
1.18
1.85
2.7
2.3
2.96
2.87
mg/l
0.30
308
2607
160
1316
1.25
1.81
2.8
2.7
9.02
8.70
umol/l
0.08
140
1165
36
231
1.57
1.80
1.4
1.2
10.48
57.75
u/ml
—
5
25
16
80
2.01
1.80
1.3
1.1
—
—
—
0
0
56
396
1.43
1.78
2.4
3.5
1.26
2.47
ratio
2.82
24
226
79
593
1.35
1.78
3.8
3.7
4.42
4.50
pmol/l
0.18
72
527
11
47
2.35
1.78
1.1
1.0
2275.55
1421.62
miu/ml
1.19
11
47
24
139
1.74
1.76
1.3
1.1
2.61
1.89
—
5
18
0
47
0.00
1.70
0.0
1.3
—
—
—
0
0
14
68
2.07
1.70
2.6
1.6
110.79
99.45
ng/l
0.13
14
68
45
308
1.48
1.70
1.3
1.2
38.25
2.58
u/ml
—
6
12
37
243
1.54
1.69
1.3
1.2
1.03
6.91
u/ml
—
6
14
236
2043
1.19
1.62
3.7
3.5
0.82
0.82
mmol/l
0.42
229
1934
5
14
3.58
1.61
1.2
1.0
—
—
—
0
0
112
898
1.27
1.60
2.9
3.0
10.77
10.73
g/l
0.04
103
832
38
255
1.51
1.59
4.8
3.3
7.41
7.57
mmol/l
0.15
38
249
22
129
1.72
1.57
1.8
1.6
50.75
65.15
%
0.71
12
80
11
50
2.21
1.57
1.5
1.1
—
—
—
0
0
58
424
1.39
1.56
1.6
1.9
3.95
6.89
iu/ml
0.69
19
99
10
44
2.28
1.55
1.4
1.4
153.40
183.22
mmol/24h
—
10
44
134
1102
1.24
1.54
2.6
2.5
36.84
42.44
u/l
0.34
116
934
276
2432
1.17
1.53
1.8
1.7
458.72
24372661.26
pmol/l
1.91
224
2031
60
443
1.37
1.53
2.6
3.6
45.64
63.12
mg/l
0.61
53
378
42
292
1.45
1.50
1.4
1.2
1.15
2.54
u/ml
—
6
27
42
293
1.45
1.47
1.4
1.2
4.08
7.03
u/ml
—
8
38
42
294
1.44
1.45
1.1
1.1
—
—
—
0
0
42
294
1.44
1.45
1.1
1.1
—
—
—
0
0
11
52
2.13
1.44
1.5
1.4
19.13
25.38
umol/l
0.31
11
45
6
22
2.74
1.43
1.2
1.2
—
—
—
0
0
59
442
1.35
1.39
2.7
3.6
82.95
93.59
mg/l
0.08
51
376
100
806
1.26
1.39
7.1
7.0
24.41
24.46
mmol/l
0.06
95
769
5
17
2.95
1.36
1.0
1.1
22.22
40.41
iu/ml
—
5
17
17
97
1.76
1.35
1.2
1.1
110.00
154.12
titre
—
5
17
14
75
1.88
1.34
1.6
1.5
—
—
—
0
0
14
75
1.88
1.34
1.7
1.5
—
—
—
0
0
9
42
2.15
1.33
2.6
2.7
0.60
0.60
mmol/l
—
9
42
11
54
2.05
1.33
1.2
1.2
—
70.10
%
—
0
10
43
309
1.41
1.31
1.8
1.6
11206.43
14243.44
e6/l
0.32
28
217
43
309
1.41
1.31
1.5
1.3
—
—
—
0
0
9
45
2.01
1.23
3.3
2.0
42.89
41.04
g/l
—
9
45
88
711
1.26
1.22
1.4
1.3
558.31
233.51
u/ml
0.57
83
653
117
1394
0.82
1.22
6.0
4.9
32.66
32.12
%
0.22
88
918
436
4027
1.13
1.22
4.1
3.5
2.36
2.35
mmol/l
0.02
397
3661
125
1050
1.21
1.22
2.5
2.4
6.40
7.51
ug/l
0.37
107
934
5
19
2.64
1.21
1.0
1.1
114.20
97.11
%
—
5
19
266
2380
1.15
1.21
2.9
3.1
2.44
2.46
mmol/l
1.01
235
2144
108
895
1.23
1.20
1.8
1.6
—
—
—
0
0
13
71
1.84
1.19
1.1
1.0
—
—
—
0
0
44
324
1.37
1.19
1.5
1.4
—
—
—
0
0
376
3451
1.13
1.16
1.8
1.7
19.42
20.02
nmol/l
0.37
330
2927
25
166
1.52
1.15
1.2
1.1
3.19
16.62
au/ml
—
7
39
110
921
1.21
1.12
4.2
3.0
61.36
64.23
ml/min/173m2
0.38
56
400
28
192
1.47
1.12
1.3
1.3
—
—
—
0
0
13
74
1.76
1.07
1.0
1.2
—
—
—
0
0
488
4568
1.11
1.05
2.1
1.9
1.40
1.36
mmol/l
0.38
414
3826
135
1160
1.18
1.05
2.5
2.2
0.20
0.21
g/l
0.26
129
1074
269
2434
1.13
1.05
2.8
1.7
1.31
1.33
mg/l
0.01
217
1902
24
162
1.49
1.04
2.3
1.7
18.87
18.75
ug/l
0.01
24
157
68
545
1.26
1.04
2.3
2.0
0.81
1.66
ug/l
1.12
63
487
208
1851
1.15
1.04
1.3
1.3
6.05
12.15
u/ml
1.51
91
688
35
255
1.38
1.03
3.3
2.7
15.92
16.09
%
0.10
35
249
11
60
1.84
1.03
1.2
1.3
0.66
1.30
nmol/l
—
5
47
11
60
1.84
1.03
1.2
1.1
0.53
0.52
ratio
—
6
38
27
188
1.45
1.02
1.7
1.4
155.00
171.31
au/ml
—
9
55
113
960
1.19
1.01
3.3
4.1
1.23
1.23
mmol/l
0.07
100
841
105
886
1.20
1.01
1.7
1.5
—
—
—
0
0
58
460
1.27
0.98
1.2
1.3
—
—
—
0
0
0
30
0.00
0.97
0.0
4.5
—
72.88
—
0
24
35
262
1.35
0.90
1.4
1.5
619.79
912.17
e6/l
0.17
28
206
149
1311
1.15
0.89
4.1
4.2
13.78
16.41
ug/l
0.18
121
1080
36
272
1.33
0.88
1.3
1.3
—
—
—
0
0
10
56
1.79
0.88
1.9
1.4
—
—
—
0
0
8
43
1.87
0.87
1.1
1.1
175.38
243.20
iu/ml
—
8
43
478
4508
1.10
0.86
5.9
5.4
2.27
2.92
ug/l
1.31
435
4087
8
44
1.82
0.86
1.1
1.7
—
—
—
0
0
28
204
1.38
0.85
1.7
1.4
—
15.19
—
0
5
6
31
1.94
0.84
1.2
1.1
—
—
—
0
0
57
462
1.24
0.83
2.6
2.0
—
—
—
0
0
740
7127
1.09
0.82
3.7
3.4
54.16
53.21
u/l
0.09
696
6701
308
2850
1.11
0.82
3.8
2.5
—
—
—
0
0
24
172
1.40
0.81
1.4
1.5
—
—
—
0
0
42
330
1.28
0.80
3.5
3.4
1.32
1.87
index
0.34
25
174
24
173
1.39
0.79
1.2
1.1
2.44
1.99
u/ml
0.08
11
101
12
74
1.63
0.78
1.6
2.7
—
—
—
0
0
95
819
1.17
0.76
11.8
10.0
0.60
0.64
%
0.47
95
814
32
244
1.32
0.76
1.2
1.4
—
—
—
0
0
32
244
1.32
0.76
1.2
1.4
—
—
—
0
0
41
324
1.27
0.75
1.3
1.4
20.78
28.60
iu/l
0.95
35
274
355
3322
1.09
0.75
4.5
4.1
0.00
0.01
estimate
1.15
133
1146
9
53
1.70
0.75
1.0
1.1
—
—
—
0
0
98
849
1.17
0.74
11.4
9.7
1.26
1.26
%
0.03
98
843
9
55
1.64
0.73
1.4
1.4
—
—
—
0
0
9
55
1.64
0.73
1.4
1.4
—
—
—
0
0
92
794
1.17
0.73
1.8
1.7
—
—
—
0
0
59
708
0.83
0.73
1.8
1.8
3.50
3.48
mmol/l
0.03
42
525
5
25
2.00
0.72
1.0
1.4
—
—
—
0
0
43
344
1.26
0.72
1.7
1.4
—
—
—
0
0
37
291
1.28
0.71
3.1
2.2
124.41
127.65
g/l
0.34
32
232
44
354
1.25
0.71
1.5
1.5
272.00
279.18
ug/g
0.09
26
211
10
61
1.64
0.68
1.0
1.6
—
—
—
0
0
10
61
1.64
0.68
1.0
1.6
—
—
—
0
0
18
127
1.42
0.68
1.7
1.3
—
—
—
0
0
33
258
1.29
0.67
1.2
1.1
3.84
3.97
—
5
29
5
28
1.79
0.66
1.2
1.7
—
0.42
—
0
6
51
422
1.22
0.65
2.0
1.8
—
—
—
0
0
17
120
1.42
0.64
4.8
2.6
—
—
—
0
0
17
120
1.42
0.64
1.1
1.1
—
—
—
0
0
56
469
1.20
0.64
1.1
1.1
—
—
—
0
0
5
29
1.73
0.64
1.6
1.8
103.40
102.38
nmol/24h
—
5
29
15
104
1.45
0.62
1.1
1.1
—
—
—
0
0
10
63
1.59
0.62
3.6
1.3
5.64
6.96
u/l
—
10
50
17
122
1.40
0.60
3.8
1.9
—
—
—
0
0
140
1267
1.12
0.59
2.1
2.4
97.11
131.28
ug/g
1.34
101
1025
41
336
1.23
0.59
1.2
1.2
0.83
0.92
g/l
1.48
41
336
6
35
1.72
0.57
1.2
1.1
—
—
—
0
0
12
81
1.49
0.57
1.5
1.5
89.17
82.59
umol/l
0.37
12
81
248
2315
1.09
0.57
1.3
1.3
0.85
1.63
u/ml
1.86
79
628
19
141
1.35
0.56
3.0
2.1
0.58
0.15
mmol/l
0.19
19
135
39
320
1.23
0.56
1.1
1.2
1.54
1.54
g/l
0.06
39
320
8
55
1.46
0.56
5.6
1.9
—
—
—
0
0
8
55
1.46
0.56
5.6
1.9
—
—
—
0
0
8
55
1.46
0.56
5.6
1.9
—
—
—
0
0
8
55
1.46
0.56
5.6
1.9
—
—
—
0
0
224
2084
1.09
0.55
1.4
1.5
2.59
2.57
g/l
0.06
154
1258
10
65
1.54
0.55
1.4
1.1
48.88
15.32
u/ml
—
5
27
15
107
1.41
0.55
3.5
1.7
—
—
—
0
0
15
107
1.41
0.55
3.5
1.7
—
—
—
0
0
15
107
1.41
0.55
3.5
1.7
—
—
—
0
0
11
74
1.49
0.53
1.5
1.5
—
—
—
0
0
9
62
1.45
0.53
1.2
1.1
—
—
—
0
0
6
39
1.54
0.53
1.2
2.7
1190.23
17.98
ug/l
—
6
31
140
1277
1.11
0.53
1.8
1.8
1.61
1.53
%
0.49
121
1093
32
259
1.24
0.53
1.5
1.4
2.17
46.83
e6/l
1.20
24
199
10
66
1.52
0.52
1.8
2.4
—
—
—
0
0
30
242
1.25
0.51
1.4
1.5
—
—
—
0
0
18
136
1.33
0.49
2.2
1.6
—
—
—
0
0
18
136
1.33
0.49
2.2
1.6
—
—
—
0
0
17
128
1.33
0.47
1.0
1.1
0.98
2.01
eliau/ml
—
6
48
18
137
1.32
0.47
2.2
1.6
—
—
—
0
0
12
85
1.42
0.47
1.3
1.6
365.86
301.97
mu/l
—
7
68
137
1258
1.10
0.47
1.5
1.4
—
—
—
0
0
378
3617
1.06
0.45
4.8
4.5
23.54
21.31
%
1.84
196
1788
14
103
1.36
0.45
3.3
3.0
13.26
13.27
%
0.00
14
103
17
130
1.31
0.44
3.8
1.8
—
—
—
0
0
13
95
1.37
0.43
1.1
1.1
—
81.83
—
0
6
18
139
1.30
0.43
1.1
1.1
4.55
0.97
u/ml
—
10
71
20
252
0.79
0.43
1.6
1.5
—
—
—
0
0
30
360
0.83
0.42
1.5
1.9
4.38
4.81
mg/l
0.08
19
275
32
267
1.20
0.42
2.3
3.5
70.56
1467.93
u/ml
0.86
27
252
5
32
1.56
0.42
1.2
1.1
—
—
—
0
0
5
32
1.56
0.42
1.2
1.1
—
—
—
0
0
89
982
0.90
0.42
2.0
2.1
3.43
3.55
ratio
0.38
71
800
159
1480
1.08
0.41
1.4
1.5
—
—
—
0
0
5
33
1.52
0.41
1.6
1.1
—
—
—
0
0
12
161
0.74
0.41
1.2
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
18
141
1.28
0.40
2.2
1.5
—
—
—
0
0
18
141
1.28
0.40
3.4
2.2
27.38
20.95
mg/l
—
8
52
17
133
1.28
0.38
1.1
1.8
53.27
32.91
ng/l
0.39
17
133
13
170
0.76
0.38
1.3
1.7
—
—
—
0
0
5
36
1.39
0.38
1.0
1.4
8.04
9.01
ug/l
—
5
36
18
143
1.26
0.37
2.2
1.5
—
—
—
0
0
32
272
1.18
0.36
1.9
1.9
6.01
25.92
iu/l
0.43
14
106
21
171
1.23
0.36
1.0
1.1
—
—
—
0
0
6
42
1.43
0.35
7.2
2.1
—
—
—
0
0
6
42
1.43
0.35
1.3
1.1
—
—
—
0
0
6
42
1.43
0.35
7.2
2.1
—
—
—
0
0
14
108
1.30
0.35
1.3
1.3
—
—
—
0
0
6
43
1.40
0.35
7.2
2.1
—
—
—
0
0
24
200
1.20
0.33
1.5
1.5
—
—
—
0
0
33
284
1.17
0.33
1.3
1.2
—
—
—
0
0
40
351
1.14
0.32
1.6
1.7
—
—
—
0
0
7
54
1.30
0.30
1.3
1.2
—
—
—
0
0
123
1309
0.93
0.29
10.8
7.2
—
—
—
0
0
42
471
0.89
0.29
1.4
1.7
0.21
0.36
mg/l
1.42
17
229
61
669
0.91
0.28
1.1
1.2
114.93
151.79
u/ml
0.36
24
257
23
195
1.18
0.28
1.3
1.2
278.56
269.33
u/ml
0.07
18
115
114
1070
1.07
0.27
2.2
2.3
13.06
13.23
nmol/l
0.08
102
969
22
187
1.18
0.26
2.9
2.0
8241.14
6417.26
u/l
—
9
74
5
72
0.69
0.26
1.6
1.3
148.32
145.78
pmol/l
—
5
72
20
235
0.85
0.26
3.2
3.5
23.79
25.91
mg/l
0.09
14
172
9
74
1.22
0.25
1.1
1.5
—
—
—
0
0
14
114
1.23
0.25
1.2
1.8
—
—
—
0
0
17
143
1.19
0.23
2.3
1.5
—
—
—
0
0
5
39
1.28
0.23
1.6
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.4
—
—
—
0
0
25
220
1.14
0.21
2.8
1.8
—
—
—
0
0
38
345
1.10
0.20
2.1
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.08
—
0
8
14
119
1.18
0.17
1.4
1.3
12026.44
114785.83
e6/l
—
9
81
72
680
1.06
0.17
2.1
1.8
—
—
—
0
0
12
101
1.19
0.16
1.5
1.2
—
—
—
0
0
6
78
0.77
0.15
2.5
2.3
17.40
18.66
nmol/l
—
6
71
9
81
1.11
0.15
1.1
1.5
—
—
—
0
0
32
295
1.09
0.14
1.1
1.1
0.63
0.70
ratio
—
7
48
12
103
1.17
0.13
1.0
1.0
—
—
—
0
0
30
277
1.09
0.13
1.4
1.5
—
—
—
0
0
16
179
0.89
0.12
7.9
5.8
12.05
12.20
mg/l
0.06
16
164
25
272
0.92
0.12
1.8
1.5
—
—
—
0
0
26
240
1.09
0.11
1.3
1.5
—
—
—
0
0
31
289
1.07
0.11
2.0
2.1
—
—
—
0
0
10
115
0.87
0.10
2.6
3.6
12.40
11.82
index
—
5
68
5
63
0.79
0.08
1.4
1.3
—
—
—
0
0
23
246
0.93
0.08
1.1
1.4
211.11
201.07
miu/ml
—
10
106
15
137
1.10
0.07
5.2
3.9
—
—
—
0
0
8
76
1.05
0.07
2.0
1.9
—
—
—
0
0
77
748
1.03
0.07
2.1
1.9
—
—
—
0
0
7
81
0.86
0.07
1.7
1.2
—
—
—
0
0
7
81
0.86
0.07
1.7
1.2
—
—
—
0
0
7
82
0.85
0.07
1.3
1.6
—
—
—
0
0
9
84
1.07
0.07
1.2
1.5
—
21.83
—
0
12
47
452
1.04
0.07
3.2
2.9
—
—
—
0
0
8
93
0.86
0.06
1.1
1.1
283.00
280.73
mg/l
—
8
80
11
99
1.11
0.06
2.6
1.4
0.18
0.35
nmol/l
1.53
11
75
35
336
1.04
0.05
1.5
1.6
33.80
12.77
u/ml
—
8
71
14
130
1.08
0.04
1.3
1.5
—
—
—
0
0
29
278
1.04
0.04
2.4
1.5
—
—
—
0
0
18
170
1.06
0.04
5.8
5.7
329.72
358.87
umol/l
0.57
18
158
12
111
1.08
0.04
1.3
1.5
—
—
—
0
0
12
112
1.07
0.03
1.3
1.5
0.94
0.96
ratio
—
7
73
12
112
1.07
0.03
1.3
1.5
1.09
1.08
ratio
—
7
73
12
112
1.07
0.03
1.3
1.5
1.26
1.23
ratio
—
7
73
35
341
1.03
0.02
6.1
4.2
3.98
3.93
mmol/l
0.29
35
336
26
252
1.03
0.02
1.2
1.4
8.74
8.13
u/l
0.10
21
202
34
332
1.02
0.01
2.6
1.7
—
—
—
0
0
19
196
0.97
0.00
1.1
1.1
—
1.12
—
0
7
269
2683
1.00
0.00
3.7
3.3
0.74
0.77
ug/l
0.25
179
1784
50
496
1.01
0.00
3.3
3.5
54902.52
3116.29
u/ml
0.47
41
428
16
159
1.01
0.00
1.0
1.0
—
—
—
0
0
32
325
0.98
0.00
2.4
1.7
—
—
—
0
0
5
52
0.96
0.00
1.0
1.3
31.80
28.94
umol/l
—
5
47
6
64
0.94
0.00
2.3
2.4
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.4
—
78.33
—
0
6
0
7
0.00
-0.00
0.0
11.9
—
—
—
0
0
17
170
1.00
-0.00
1.1
1.1
1.52
1.52
g/l
0.01
17
153
10
100
1.00
-0.00
1.1
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
3.2
3.7
1.00
1.37
%
—
6
61
7
71
0.99
-0.00
1.1
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
0.44
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
1745.20
—
0
5
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
63
0.95
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.02
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
38.83
—
0
6
5
49
1.02
-0.00
2.4
3.1
19.80
29.90
umol/l
—
5
35
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
3.5
3.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINALDETACHOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINALDETACHOTH | 1.211 [1.03, 1.42] | 0.018 |
| Birth year | 0.992 [0.98, 1.0] | 0.08 |
During the follow-up period (1.1.1998 — 31.12.2019), 411 out of 2315 females with H7_RETINALDETACHOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINALDETACHOTH | 1.138 [0.98, 1.33] | 0.096 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 492 out of 2585 males with H7_RETINALDETACHOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINALDETACHOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | 0.207% |
| 5 | 0.699% | 1.414% |
| 10 | 1.675% | 3.391% |
| 15 | 3.173% | 6.485% |
| 20 | 5.648% | 10.842% |
Relationships between endpoints
↥Index endpoint: H7_RETINALDETACHOTH – Other, unspecified and serous retinal detachments
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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