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Malignant neoplasm of bone and articular cartilage of other and unspecified sites, including Hilmo

C3_BONE_CARTILAGE_NAS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C41
  • Hospital discharge: ICD-9 170
  • Hospital discharge: ICD-8 170
  • Cause of death: ICD-10 C41
  • Cause of death: ICD-9 170
  • Cause of death: ICD-8 170
  • Cause of death: excluded ICD-9 170[4-5]|170[7-8]
  • Cause of death: excluded ICD-8 170[4-5]|170[7-8]
  • Cancer registry: Topography ICD-O-3 C41
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

521

4. Check minimum number of events

None

521

5. Include endpoints

None

521

6. Filter based on genotype QC (FinnGen only)

451

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of bone and articular cartilage of other and unspecified sites, including Hilmo based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 451 206 245
Unadjusted period prevalence (%) 0.09 0.07 0.11
Median age at first event (years) 57.72 56.71 58.57

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
466
Matched controls
4660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
128.5
281.3
143
16
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
97.7
190.9
100
13
XX3DW
NOMESCO Finland
Time consuming IT work
19.3
140.9
121
83
130
Kela drug reimbursment
Malignant tumour
+∞
134.0
122
*
JN4AD
NOMESCO Finland
Body CT examination
13.5
123.1
133
134
JN4BD
NOMESCO Finland
Extensive body CT
15.6
122.3
118
99
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
721.3
117.5
111
*
A04AA01
ATC
ondansetron; systemic, rectal
21.5
111.4
88
50
XW000
NOMESCO Finland
Bone marrow biopsy
25.8
107.7
78
36
N02AA05
ATC
oxycodone; systemic
7.3
93.1
188
396
A03FA01
ATC
metoclopramide; systemic, rectal
7.3
85.6
161
313
WF049
NOMESCO Finland
Radiotherapy of metastasis
975.2
85.4
81
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
20.3
78.0
62
35
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
74.0
69
*
Z51.5
ICD-10 Finland
Palliative care
11.3
72.6
83
88
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
70.6
66
*
L03AA02
ATC
filgrastim; parenteral
777.8
70.0
67
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
19.2
68.9
56
33
WZC00
NOMESCO Finland
Treatment plan or consultation
5.0
66.6
245
841
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
195.0
65.9
67
*
A04AA02
ATC
granisetron; systemic, transdermal
723.9
65.6
63
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
59.7
56
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
13.7
58.4
57
47
L03AA13
ATC
pegfilgrastim; parenteral
632.0
58.0
56
*
WF002
NOMESCO Finland
Radical radiotherapy
215.9
56.3
57
*
C90.0
ICD-10 Finland
Multiple myeloma
580.9
53.6
52
*
JN4CD
NOMESCO Finland
Very extensive body CT
19.4
51.3
41
23
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
543.2
50.4
49
*
WW500
NOMESCO Finland
Blood transfusion
13.3
48.7
48
40
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
46.7
44
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
45.6
43
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
41.3
39
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
15.5
40.3
36
25
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
39.1
37
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
37.0
35
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
37.0
35
*
C41.20
ICD-10 Finland
Malignant tumor of the spine without histology
+∞
35.9
34
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
10.8
35.9
40
40
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.7
35.6
61
103
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
374.0
35.4
35
*
N03AX16
ATC
[U] pregabalin
3.5
35.0
166
631
WX302
NOMESCO Finland
Thoracal epidural anesthesy
10.8
34.9
39
39
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.1
34.5
55
86
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
33.8
32
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
33.3
164
636
B01AB10
ATC
tinzaparin; parenteral
4.9
33.0
82
195
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
32.7
31
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.5
32.3
92
244
115
Kela drug reimbursment
Breast cancer
+∞
31.6
30
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
11.0
31.0
34
33
C41.49
ICD-10 Finland
Malignant tumor of the pelvic bones, sacrum and coccyx other or unspecified histology
+∞
30.6
29
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
29.9
133
480
153
Kela drug reimbursment
Lenalidomid
+∞
29.5
28
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
29.5
28
*
WZC30
NOMESCO Finland
Teaching
3.9
29.4
104
322
B01AB05
ATC
enoxaparin; parenteral
3.0
28.6
190
865
ZXE30
NOMESCO Finland
More than five and less than seven hours
7.6
28.4
42
60
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
27.7
283
1615
ZX120
NOMESCO Finland
Intravenous
5.1
27.5
62
135
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
27.4
26
*
L04AX04
ATC
lenalidomide; oral
+∞
27.4
26
*
329
Kela drug reimbursment
Lenalidomide
+∞
27.4
26
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
27.4
26
*
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
27.4
26
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
27.4
26
*
HA1AA
NOMESCO Finland
X-ray mammography
8.0
27.1
38
51
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
26.3
25
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
26.3
25
*
C41.29
ICD-10 Finland
Malignant tumor of the spine other or unspecified histology
+∞
26.3
25
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
99.1
25.9
28
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
25.2
24
*
C41.40
ICD-10 Finland
Pelvic bones, sacrum and coccyx
+∞
25.2
24
*
WX402
NOMESCO Finland
General anaesthesia
3.1
24.9
134
536
GD1AD
NOMESCO Finland
Thorax CT examination
5.1
24.5
55
119
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
24.2
23
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.2
23.2
41
71
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
23.1
22
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
23.1
22
*
M05BX04
ATC
denosumab; parenteral
4.9
22.4
53
120
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
54.9
22.3
26
5
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
22.1
21
*
116
Kela drug reimbursment
Prostate cancer
+∞
22.1
21
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
22.1
21
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
22.1
21
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
22.1
21
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.8
21.9
53
122
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.7
21.8
42
79
D70.82
ICD-10 Finland
Drug-induced neutropenia
120.7
21.8
23
*
JN6AD
NOMESCO Finland
CT of torso and neck
35.7
21.4
27
8
NF3AA
NOMESCO Finland
Femur X-ray examination
6.8
21.2
34
53
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
21.0
20
*
9101
FHL
Bone biopsy
+∞
21.0
20
*
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
21.0
20
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
219.4
20.7
21
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
219.4
20.7
21
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
219.4
20.7
21
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.4
20.6
35
58
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
20.5
82
272
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.1
20.3
61
166
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
19.9
19
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
19.9
19
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
19.9
19
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
76.9
19.9
22
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
19.1
88
318
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
29.2
18.9
25
9
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
+∞
18.9
18
*
A79
ICPC
Malignancy NOS
+∞
18.9
18
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
18.9
18
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
18.9
18
*
R4110
NOMESCO Finland
Physiotherapy
2.5
18.2
157
785
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
18.2
81
286
A06AH03
ATC
naloxegol; oral
34.5
18.1
23
7
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
28.0
18.0
24
9
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
23.9
17.9
25
11
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.0
17.9
40
86
HAC20
NOMESCO Finland
Total mastectomy
+∞
17.8
17
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
17.8
17
*
C41.4
ICD-10 Finland
Malignant neoplasm: Pelvic bones, sacrum and coccyx
+∞
17.8
17
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
17.8
17
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
17.6
177
946
R50.9
ICD-10 Finland
Fever, unspecified
2.9
16.8
90
353
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
16.8
16
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
16.8
16
*
C41.00
ICD-10 Finland
Malignant tumor of the skull or facial bone without histology
+∞
16.8
16
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
16.8
16
*
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
16.8
16
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
16.8
16
*
N02BF02
ATC
pregabalin; oral
3.9
16.2
51
143
C41.09
ICD-10 Finland
Malignant tumor of the skull or facial bones other or unspecified histology
+∞
15.7
15
*
L01BC06
ATC
capecitabine; oral
+∞
15.7
15
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.3
15.7
65
219
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
88.1
15.7
17
*
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
88.1
15.7
17
*
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
5.5
15.5
31
60
ZXE40
NOMESCO Finland
More than seven and less than nine hours
13.7
15.4
26
20
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.6
15.3
37
85
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
15.2
74
274
A04AA55
ATC
palonosetron, combinations; systemic
+∞
14.7
14
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
14.7
14
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
14.7
14
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
14.7
14
*
9370/3-C41.4
ICD-O-3
Chordoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
14.7
14
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
14.7
14
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
14.7
14
*
B01AB04
ATC
dalteparin; parenteral
4.8
14.2
33
73
L02BG04
ATC
letrozole; oral
18.3
14.0
21
12
HAB40
NOMESCO Finland
Wedge excision of mammary gland
77.5
13.7
15
*
L02BA01
ATC
tamoxifen; oral
77.5
13.7
15
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
13.6
179
1048
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
13.6
13
*
C41.3
ICD-10 Finland
Malignant neoplasm: Ribs, sternum and clavicle
+∞
13.6
13
*
L71
ICPC
Malignant neoplasm musculoskeletal
+∞
13.6
13
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
13.6
13
*
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
+∞
13.6
13
*
C41.30
ICD-10 Finland
Malignant tumor of the ribs, sternum and clavicle without histology
+∞
13.6
13
*
ZX112
NOMESCO Finland
Subcutaneous
16.8
13.6
21
13
WZC15, ,
NOMESCO Finland
144.0
13.5
14
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.1
13.1
37
96
H02AB09
ATC
hydrocortisone; systemic
6.4
13.0
22
36
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.5
13.0
46
140
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
13.0
96
440
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
12.9
61
222
1700A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Bones of skull and face, except mandible[KALLON JA KASVOJEN LUUSYÖPÄ, OSTEOSARCOMA]
+∞
12.6
12
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
12.6
12
*
M05BA02
ATC
clodronic acid; systemic
+∞
12.6
12
*
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
12.6
12
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
12.6
12
*
9731/3-C41.2
ICD-O-3
Plasmacytoma, NOS, of vertebral column
+∞
12.6
12
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
12.6
12
*
A04AD12
ATC
aprepitant; systemic
+∞
12.6
12
*
9680/3-C41.4
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
12.6
12
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
133.5
12.5
13
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.7
12.2
23
42
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
12.2
69
276
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
13.9
12.0
20
15
ZZR00
NOMESCO Finland
Flap of skin
48.0
11.9
14
*
A02BC02
ATC
pantoprazole; systemic
2.1
11.8
325
2446
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
30.9
11.7
15
5
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
30.9
11.7
15
5
XX2RW, ,
NOMESCO Finland
19.5
11.7
17
9
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.0
11.6
25
52
C41.99
ICD-10 Finland
Malignant tumor in unspecified localization in bone and articular cartilage other or unspecified histology
+∞
11.5
11
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
11.5
11
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
11.5
11
*
C41.06
ICD-10 Finland
Chondrosarcoma of the skull or facial bones except maxilla
+∞
11.5
11
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
11.5
11
*
NAR00
NOMESCO Finland
Complete excision of tumour of bone or cartilage of spine, unspecified
+∞
11.5
11
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
11.5
11
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
11.5
11
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
11.5
11
*
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
11.5
11
*
9731/3-C41.3
ICD-O-3
Plasmacytoma, NOS, of rib, sternum, clavicle and associated joints
+∞
11.5
11
*
C41.90
ICD-10 Finland
Malignant tumor in unspecified localization in bone and articular cartilage without histology
+∞
11.5
11
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
11.5
11
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
11.5
11
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
11.5
11
*
WW409
NOMESCO Finland
Other aferesis
+∞
11.5
11
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
122.9
11.5
12
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
122.9
11.5
12
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.1
11.3
24
49
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.8
11.0
34
94
ZZA00
NOMESCO Finland
Split skin graft
5.6
11.0
21
39
J01MA12
ATC
levofloxacin; systemic
2.3
10.9
95
465
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
16.0
10.9
17
11
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
10.7
47
163
N02AX02
ATC
tramadol; systemic, rectal
1.9
10.7
216
1443
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
10.7
70
301
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
10.4
10.6
20
20
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
5.0
10.6
23
48
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.8
10.6
33
92
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
8.0
10.5
23
30
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
112.5
10.5
11
*
XX1AD
NOMESCO Finland
Other CT-examination
112.5
10.5
11
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
10.5
10
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
10.5
10
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
10.5
10
*
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
+∞
10.5
10
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
10.5
10
*
9680/3-C41.2
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of vertebral column
+∞
10.5
10
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
10.5
10
*
C41.41
ICD-10 Finland
Osteosarcoma of the pelvic bones, sacrum and coccyx
+∞
10.5
10
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
33.3
10.4
13
*
M04AA01
ATC
allopurinol; systemic
2.4
10.2
82
388
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.6
10.1
24
54
J05AB01
ATC
aciclovir; systemic
2.1
10.1
112
605
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
10.0
67
291
L02AE02
ATC
leuprorelin; implant, parenteral
17.2
9.9
15
9
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
9.5
61
259
JAG60
NOMESCO Finland
Reconstruction of abdominal wall using prosthetic material
102.0
9.4
10
*
A06AD11
ATC
lactulose; oral
2.3
9.4
84
414
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
30.7
9.4
12
*
AA1AA
NOMESCO Finland
Head X-ray examination
12.7
9.4
16
13
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
9.4
9
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
9.4
9
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.0
9.4
43
153
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
22.2
9.4
13
6
ZXE00
NOMESCO Finland
One hour or less
1.9
9.2
175
1135
R4190
NOMESCO Finland
Nutritional therapy
4.2
9.1
24
59
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
16.0
9.1
14
9
GA1CG
NOMESCO Finland
Extensive MRI of chest
37.5
9.1
11
*
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
37.5
9.1
11
*
9102
FHL
Trepanation or removal of the local bone process
19.1
9.0
13
7
N07BC02
ATC
methadone; systemic
51.0
8.7
10
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.7
8.7
28
80
GBB00
NOMESCO Finland
Tracheostomy
11.9
8.6
15
13
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
7.6
8.5
19
26
ED1AA
NOMESCO Finland
Mandibular X-ray examination
28.1
8.5
11
*
L02BG06
ATC
exemestane; oral
91.7
8.4
9
*
ZX121
NOMESCO Finland
Central venous catheter
91.7
8.4
9
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
91.7
8.4
9
*
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
5.0
8.4
18
37
C41.39
ICD-10 Finland
Malignant tumor of the ribs, sternum and clavicle other or unspecified histology
+∞
8.4
8
*
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
+∞
8.4
8
*
17041
ICD-8 Finland
Malignant neoplasm of bone, Long bones of upper limb and scapula
+∞
8.4
8
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
8.4
8
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
+∞
8.4
8
*
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
+∞
8.4
8
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
8.4
8
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
8.4
8
*
C41.89
ICD-10 Finland
Malignant overall tumor of bone and articular cartilage other or unspecified histology
+∞
8.4
8
*
WW402
NOMESCO Finland
Leucoferesis
+∞
8.4
8
*
17001
ICD-8 Finland
Malignant neoplasm of bone, Bones of skull and face
+∞
8.4
8
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
8.4
8
*
9731/3-C41.4
ICD-O-3
Plasmacytoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
8.4
8
*
C41.2
ICD-10 Finland
Malignant neoplasm: Vertebral column
+∞
8.4
8
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
8.4
8
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
8.4
8
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
8.4
8
*
ZXA05
NOMESCO Finland
Left side
1.9
8.3
121
715
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.1
8.2
22
55
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
12.0
8.1
14
12
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
8.1
106
604
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
22.5
8.0
11
5
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
22.5
8.0
11
5
ZXD05
NOMESCO Finland
Urgent procedure
1.8
7.9
140
879
B03XA02
ATC
darbepoetin alfa; parenteral
8.7
7.9
16
19
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
15.3
7.7
12
8
JDB10
NOMESCO Finland
Percutaneous gastrostomy
15.3
7.7
12
8
H02AB06
ATC
prednisolone; systemic
1.7
7.7
217
1558
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
45.8
7.7
9
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
45.8
7.7
9
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.5
7.6
26
77
WX610
NOMESCO Finland
Patient controlled analgesia
18.7
7.6
11
6
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
25.5
7.6
10
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
25.5
7.6
10
*
JN5JR
NOMESCO Finland
Extensive PET-CT of upper body metabolism (eyebrows to thighs)
25.5
7.6
10
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
9.1
7.6
15
17
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
7.6
170
1144
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
81.3
7.4
8
*
ZZR10
NOMESCO Finland
Flap of skin and muscle
81.3
7.4
8
*
GA5AA
NOMESCO Finland
Rib X-ray examination
81.3
7.4
8
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.0
7.4
17
25
AA1BD
NOMESCO Finland
Extensive CT of head and brain
6.4
7.3
18
29
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
7.3
7
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
7.3
7
*
C49.39
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax other or unspecified tumor
+∞
7.3
7
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
7.3
7
*
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
+∞
7.3
7
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
7.3
7
*
L02BB03
ATC
bicalutamide; oral
+∞
7.3
7
*
C41.10
ICD-10 Finland
Malignant tumor of the lower jaw without histology
+∞
7.3
7
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
7.3
7
*
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
7.3
7
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
7.3
7
*
C41.91
ICD-10 Finland
Osteosarcoma in unspecified localization in bone and articular cartilage
+∞
7.3
7
*
C49.30
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax without histology
+∞
7.3
7
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
7.3
7
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
7.3
7
*
X76
ICPC
Malignant neoplasm breast female
+∞
7.3
7
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
7.3
7
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
7.3
7
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
7.3
7
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
7.3
7
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
7.3
7
*
C41.0
ICD-10 Finland
Malignant neoplasm: Bones of skull and face
+∞
7.3
7
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
30.5
7.2
9
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
20.4
7.2
10
5
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
12.3
7.1
12
10
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.3
7.1
26
81
G82.2
ICD-10 Finland
Paraplegia, unspecified
14.0
6.9
11
8
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
6.9
80
435
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
40.7
6.8
8
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
6.7
60
295
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.1
6.7
18
45
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
8.0
6.7
14
18
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
6.6
42
178
ZXC95
NOMESCO Finland
Use of surgical navigator
10.2
6.6
12
12
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.0
6.5
18
46
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.0
6.5
29
102
TPX15
NOMESCO Finland
Removal of vascular injection port
70.8
6.4
7
*
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
70.8
6.4
7
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
70.8
6.4
7
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
70.8
6.4
7
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
70.8
6.4
7
*
Y77
ICPC
Malignant neoplasm prostate
70.8
6.4
7
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
9.4
6.3
12
13
D70.89
ICD-10 Finland
Neutropenic splenomegaly
18.3
6.3
9
5
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
6.3
6
*
AAP00
NOMESCO Finland
Biopsy of skull
+∞
6.3
6
*
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
+∞
6.3
6
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
6.3
6
*
NK6AT
NOMESCO Finland
Bone biopsy with ultrasound guidance
+∞
6.3
6
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
+∞
6.3
6
*
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
+∞
6.3
6
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
6.3
6
*
17061
ICD-8 Finland
Malignant neoplasm of bone, Pelvic bones, sacrum, coccyx
+∞
6.3
6
*
L02BG03
ATC
anastrozole; oral
+∞
6.3
6
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
6.3
6
*
C49.29
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip other or unspecified tumor
+∞
6.3
6
*
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
+∞
6.3
6
*
9731/3-C41.9
ICD-O-3
Plasmacytoma, NOS, of bone, NOS
+∞
6.3
6
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
6.3
6
*
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
+∞
6.3
6
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
6.3
6
*
C41.92
ICD-10 Finland
Chondrosarcoma in unspecified localization in bone and articular cartilage
+∞
6.3
6
*
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
6.3
6
*
L02BA03
ATC
fulvestrant; parenteral
+∞
6.3
6
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
7.2
6.3
14
20
ZX108
NOMESCO Finland
Inhalation
27.1
6.2
8
*
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
27.1
6.2
8
*
JFF23
NOMESCO Finland
Transversostomy
27.1
6.2
8
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
3.6
6.2
20
57
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.5
6.2
17
32
N02BE01
ATC
paracetamol; systemic, rectal
2.0
6.2
407
3598
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.1
6.2
25
83
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.8
6.2
13
17
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
6.1
130
854
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
12.7
6.1
10
8
J01FF01
ATC
clindamycin; systemic
1.7
6.1
123
796
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
6.0
194
1418
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
6.0
78
440

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
139
95
20.43
163.22
1.6
1.3
—
—
—
0
0
90
120
9.06
66.01
11.0
1.2
39.21
45.82
mg/l
0.44
79
104
90
120
9.06
66.01
10.9
1.2
34.67
33.78
mg/l
0.02
79
105
84
105
9.54
64.82
9.7
1.2
4.17
1.33
ratio
0.61
54
62
50
35
15.88
56.15
3.2
1.1
—
—
—
0
0
110
253
5.38
46.85
9.3
1.4
—
—
—
0
0
40
30
14.49
43.03
1.5
1.2
—
—
—
0
0
90
205
5.20
38.35
4.4
1.6
42.44
2.58
ug/l
0.84
68
151
50
62
8.91
38.29
4.5
1.3
—
—
—
0
0
309
1678
3.50
36.51
7.7
4.1
34.36
36.02
g/l
5.00
296
1568
40
43
10.08
34.05
3.1
1.8
0.49
1.50
g/24h
1.37
22
27
238
1143
3.21
33.83
3.1
1.6
—
—
—
0
0
344
2057
3.57
33.47
20.7
6.3
4.28
4.31
e9/l
0.06
314
1782
329
1918
3.43
33.32
13.9
4.1
10.81
12.23
umol/l
0.57
318
1822
218
1041
3.06
30.54
6.4
3.9
—
—
—
0
0
96
281
4.04
29.36
1.4
1.1
—
—
—
0
0
300
1739
3.04
29.03
14.1
6.6
1.20
1.21
mmol/l
0.43
283
1593
292
1668
3.01
29.03
4.6
2.5
—
—
estimate
—
0
0
318
1927
3.05
27.93
9.2
5.5
0.58
0.59
e9/l
0.36
288
1654
322
1965
3.07
27.91
18.9
6.6
1.21
1.21
mmol/l
0.61
282
1724
225
1135
2.90
27.90
4.6
2.1
—
—
—
0
0
321
1963
3.04
27.57
9.3
5.6
1.58
1.85
e9/l
8.65
292
1723
324
1995
3.05
27.41
9.5
5.7
0.19
0.20
e9/l
0.80
293
1743
317
1940
2.98
26.91
9.2
5.5
0.03
0.04
e9/l
2.82
286
1671
296
1753
2.89
26.62
9.0
5.5
2.70
3.03
%
1.29
290
1647
295
1752
2.86
26.25
9.2
5.6
9.14
8.84
%
0.77
289
1650
85
247
3.99
26.10
1.4
1.5
—
—
—
0
0
292
1751
2.79
25.05
9.1
5.6
0.61
0.68
%
1.45
286
1646
91
286
3.71
24.90
5.2
3.9
1.02
0.39
%
2.61
46
57
229
1224
2.71
24.58
8.4
5.4
—
—
—
0
0
93
300
3.62
24.46
5.9
4.0
1.92
0.80
%
3.20
49
58
294
1790
2.74
24.11
9.2
5.6
23.60
27.56
%
7.38
289
1705
234
1275
2.68
24.01
7.5
2.1
2.34
2.35
mmol/l
0.62
219
1117
88
289
3.52
22.41
6.1
4.1
0.23
0.06
%
1.39
43
48
178
873
2.68
22.22
4.8
2.2
—
—
—
0
0
30
12
26.59
22.03
2.2
1.0
—
—
—
0
0
105
396
3.13
21.29
1.7
1.6
—
—
—
0
0
117
485
2.89
19.94
10.3
9.3
5.34
5.14
kpa
1.35
112
468
117
485
2.89
19.94
10.3
9.3
13.80
11.76
kpa
2.61
112
469
112
456
2.92
19.71
1.7
1.6
—
—
—
0
0
288
1860
2.44
18.97
13.3
16.7
1.19
1.30
inr
3.63
252
1553
203
1126
2.42
18.87
9.8
3.3
7.40
7.40
ph
0.60
159
799
114
479
2.83
18.85
10.5
9.3
1.37
1.15
mmol/l
0.27
94
396
115
488
2.80
18.65
10.5
9.2
7.41
7.41
ph
0.09
67
284
84
302
3.17
18.30
6.6
4.2
0.37
0.00
%
0.54
38
45
26
37
7.38
17.55
3.7
1.6
374.73
1222.97
mg
0.98
26
37
385
2901
2.88
17.43
17.5
5.6
91.27
76.96
u/l
3.90
376
2716
23
9
26.78
17.06
1.4
1.0
—
—
—
0
0
330
2324
2.44
17.02
9.2
5.1
6.59
6.73
mmol/l
0.71
322
2214
24
13
19.39
16.17
1.3
1.0
—
—
—
0
0
179
1020
2.23
14.82
4.4
2.5
323.26
351.94
umol/l
3.32
169
897
86
351
2.78
14.78
5.4
2.0
80.76
66.82
e9/l
1.51
67
260
48
139
3.73
14.57
1.9
1.7
2.57
1.87
ug/l
0.17
41
122
18
5
37.34
14.54
8.0
1.0
25.89
16.20
u/ml
—
18
5
68
257
2.93
13.42
8.9
2.9
1.22
1.22
mmol/l
0.06
63
216
117
578
2.37
13.42
2.5
2.0
—
—
—
0
0
22
17
13.52
13.04
1.5
2.4
15.59
10.82
%
0.69
22
17
22
17
13.52
13.04
1.7
2.5
70.86
70.47
%
0.02
22
17
21
16
13.68
12.54
1.1
1.0
—
—
—
0
0
113
572
2.29
12.13
1.8
1.9
—
—
—
0
0
22
21
10.93
11.88
1.9
2.5
30.66
44.09
%
2.18
22
21
11
0
+∞
11.50
13.2
0.0
0.26
—
umol/l
—
11
0
197
1277
1.94
10.71
4.0
3.2
46.77
104.83
e6/l
0.55
158
960
160
970
1.99
10.54
1.5
1.4
—
—
—
0
0
244
1705
1.90
10.50
21.0
9.6
0.01
0.00
e9/l
0.72
205
1382
137
788
2.05
10.45
4.6
2.1
2.47
2.44
mmol/l
1.63
126
698
146
861
2.01
10.38
3.1
2.6
5.11
5.41
e6/l
0.10
133
778
174
1093
1.94
10.29
3.6
3.1
0.79
0.37
e6/l
0.50
130
777
211
1432
1.87
9.71
4.8
3.9
80.63
101.09
e6/l
0.24
164
991
114
628
2.08
9.69
3.3
2.0
29.29
29.44
s
0.12
109
609
139
826
1.97
9.56
8.1
4.2
—
—
—
0
0
13
6
22.23
9.39
1.6
3.2
4.38
3.17
%
—
13
6
13
6
22.23
9.39
1.7
3.2
41.00
22.17
%
—
13
6
20
41
5.05
9.39
3.0
1.3
32.20
33.17
pg
0.37
20
41
19
22
8.95
9.37
4.6
3.5
—
—
—
0
0
19
24
8.20
8.93
3.4
1.2
—
—
—
0
0
15
12
12.87
8.92
1.9
2.1
33.00
173.25
e6/l
1.51
15
12
126
745
1.95
8.68
4.1
2.9
547.29
529.65
mosm/kgh2o
0.42
114
645
89
465
2.13
8.62
1.9
1.7
—
—
—
0
0
26
71
3.82
8.57
4.7
2.6
59.76
58.67
%
0.15
26
71
31
96
3.39
8.50
2.1
1.6
10.03
7.34
u/l
0.55
23
79
169
1108
1.82
8.41
4.9
3.8
0.00
0.00
estimate
-0.00
57
366
313
2472
1.81
8.14
5.9
4.7
12.17
1697.02
e6/l
—
6
42
171
1135
1.80
8.11
4.0
3.3
—
—
—
0
0
19
43
4.56
7.97
2.1
2.8
—
—
—
0
0
62
293
2.29
7.65
3.6
4.8
7.42
7.42
ph
0.57
51
235
54
245
2.36
7.31
3.8
6.2
—
—
—
0
0
109
649
1.89
7.22
3.6
2.5
11.86
13.25
umol/l
1.10
101
598
10
5
20.39
7.16
2.0
1.0
—
—
—
0
0
95
543
1.94
7.11
3.3
2.6
22.18
23.35
%
0.32
89
506
73
383
2.07
6.93
15.3
9.9
—
—
—
0
0
80
435
2.01
6.89
3.3
2.4
5.68
6.60
umol/l
0.65
73
378
100
594
1.87
6.63
3.5
2.5
2.22
2.30
g/l
0.72
94
549
20
55
3.75
6.54
1.4
1.5
—
—
—
0
0
19
51
3.84
6.42
4.9
3.0
4.19
4.27
e9/l
0.05
19
51
84
477
1.93
6.37
3.9
2.6
3.65
4.72
e9/l
2.37
78
414
151
1032
1.69
6.14
2.4
2.3
3.01
2.81
mg/l
0.38
132
882
158
1097
1.67
6.03
14.6
4.4
—
—
—
0
0
69
380
1.96
5.71
15.6
9.0
1.14
1.43
mmol/l
2.60
69
372
13
21
6.33
5.42
1.7
1.6
485.75
567.33
e6/l
—
8
15
16
43
3.82
5.41
1.4
1.3
—
—
—
0
0
16
43
3.82
5.41
1.4
1.3
—
—
—
0
0
16
43
3.82
5.41
1.4
1.3
—
—
—
0
0
16
43
3.82
5.41
1.4
1.3
—
—
—
0
0
5
0
+∞
5.22
1.0
0.0
—
—
—
0
0
212
1625
1.56
5.19
4.5
3.9
28.71
62.96
ng/l
1.00
174
1209
18
56
3.30
4.94
1.1
1.1
—
—
—
0
0
11
18
6.23
4.63
4.2
1.1
41.88
39.94
g/l
0.51
11
18
60
341
1.87
4.52
13.7
4.1
7.39
7.36
ph
0.98
48
237
166
1238
1.53
4.43
2.5
2.3
51.11
61.52
u/l
1.65
161
1151
179
1357
1.52
4.42
4.0
3.3
1085.00
1550.42
ng/l
1.56
162
1158
310
2635
1.53
4.39
5.5
4.5
—
3.91
—
0
5
9
12
7.62
4.37
1.6
2.1
14.33
21.17
%
—
9
12
7
6
11.82
4.29
1.1
1.0
—
—
—
0
0
120
838
1.58
4.27
2.8
1.8
2.05
1.20
mg/l
0.50
102
656
9
13
7.03
4.18
1.6
2.1
29.00
20.31
%
—
9
13
9
13
7.03
4.18
3.6
1.3
71.78
78.85
nmol/l
—
9
13
357
3149
1.57
4.10
37.5
17.2
14.24
13.54
%
14.21
351
3112
14
42
3.41
4.07
1.3
1.2
—
—
—
0
0
77
492
1.68
3.89
1.4
1.5
—
—
—
0
0
47
261
1.89
3.81
5.7
3.5
—
—
—
0
0
14
44
3.25
3.80
4.3
1.8
3.62
95.38
u/ml
0.55
14
44
7
8
8.86
3.78
2.0
1.3
0.67
0.61
mmol/l
—
7
8
115
816
1.54
3.78
3.8
1.3
2.28
2.50
g/l
0.46
90
489
247
2045
1.44
3.71
4.9
3.8
0.00
0.00
estimate
-0.00
60
396
25
110
2.34
3.68
2.6
1.4
20.21
26.90
iu/l
0.46
20
92
19
73
2.67
3.68
5.2
4.3
—
—
—
0
0
250
2079
1.44
3.64
5.0
3.9
0.00
0.00
estimate
-0.00
61
403
11
25
4.48
3.64
1.5
1.1
—
—
—
0
0
215
1741
1.44
3.61
2.6
2.7
78.10
78.25
nmol/l
0.03
204
1569
20
81
2.54
3.51
1.4
1.4
—
—
—
0
0
39
211
1.93
3.43
3.7
5.1
—
—
—
0
0
409
3786
1.66
3.20
34.8
14.1
28.38
24.02
mg/l
2.04
383
3049
248
2090
1.40
3.19
4.9
3.9
0.00
0.01
estimate
0.50
58
375
93
655
1.52
3.13
3.7
2.9
2.91
2.15
e6/l
0.32
46
310
6
8
7.58
3.06
3.5
1.4
13.12
25.51
u/l
—
6
8
72
483
1.58
3.00
7.6
3.7
7.38
7.38
ph
0.21
45
288
70
472
1.57
2.86
7.5
3.6
2.50
1.85
mmol/l
0.86
63
404
31
166
1.93
2.84
2.4
1.6
1.34
1.52
g/l
0.61
25
149
21
412
0.49
2.74
1.5
1.5
—
—
—
0
0
191
1571
1.37
2.72
5.2
3.8
0.04
0.00
estimate
0.44
53
326
8
19
4.26
2.69
1.4
1.2
—
—
—
0
0
160
1281
1.38
2.68
4.3
2.7
35.90
33.58
u/l
0.32
153
1208
12
45
2.71
2.47
1.4
1.6
16.23
29.60
ng/l
1.82
12
45
22
114
1.98
2.24
1.2
1.1
—
—
—
0
0
10
35
2.90
2.22
1.0
1.1
88.00
103.54
pmol/l
—
10
35
17
80
2.17
2.21
1.9
1.4
43.18
58.63
mmol/l
1.42
11
70
362
3861
0.72
2.20
5.4
6.1
2.58
2.65
mmol/l
0.75
329
3593
31
182
1.75
2.17
1.3
1.3
—
—
—
0
0
14
61
2.34
2.16
1.1
1.1
—
—
—
0
0
20
102
2.00
2.13
1.2
2.0
12.13
11.23
mg/l
0.17
20
96
25
139
1.84
2.09
5.2
2.8
154.50
284.04
mg/l
1.47
16
51
13
273
0.46
2.09
1.0
1.3
—
—
—
0
0
9
31
2.94
2.08
1.1
1.2
—
—
—
0
0
7
21
3.37
1.97
1.0
1.3
—
—
—
0
0
196
1687
1.28
1.85
4.1
3.5
6.40
6.22
ph
1.37
113
953
19
101
1.92
1.83
1.4
1.3
322.00
332.25
ug/g
—
7
57
414
3937
1.46
1.83
39.1
17.9
139.06
139.76
mmol/l
5.59
408
3866
358
3800
0.75
1.81
5.0
5.4
4.43
4.54
mmol/l
1.17
326
3547
9
35
2.60
1.81
3.1
1.6
17.11
16.82
%
—
9
35
414
3940
1.45
1.79
39.6
18.0
3.99
4.00
mmol/l
0.24
408
3856
14
67
2.12
1.77
2.5
3.8
8.54
10.33
pmol/l
0.29
14
67
22
125
1.80
1.75
3.4
1.7
—
—
—
0
0
91
710
1.35
1.75
1.8
1.8
1356.14
1183.03
nmol/l
0.62
70
535
56
402
1.45
1.74
1.4
1.4
—
—
—
0
0
8
30
2.70
1.73
1.1
1.2
—
—
—
0
0
5
13
3.87
1.72
1.4
1.5
—
—
—
0
0
56
758
0.70
1.70
1.5
1.3
78.81
35.77
iu/ml
0.46
20
233
6
19
3.18
1.66
1.0
1.1
7.45
7.39
ph
—
6
11
49
347
1.46
1.64
2.1
2.0
0.00
0.00
estimate
—
9
72
6
20
3.03
1.58
1.0
1.2
—
—
—
0
0
12
57
2.13
1.56
4.3
2.9
—
—
—
0
0
49
351
1.44
1.55
3.6
2.3
0.32
0.34
e6/l
0.04
49
331
148
1724
0.79
1.54
1.9
1.9
1.44
1.32
mmol/l
0.84
122
1451
8
33
2.45
1.54
2.1
1.1
—
—
—
0
0
105
854
1.30
1.51
1.7
1.8
470.74
27143285.96
pmol/l
0.77
87
700
358
3778
0.77
1.51
4.9
5.3
1.37
1.45
mmol/l
2.98
325
3502
13
65
2.03
1.50
1.6
1.3
—
—
—
0
0
9
37
2.46
1.48
1.1
1.2
—
—
—
0
0
9
37
2.46
1.48
4.6
1.6
83.60
91.05
%
—
9
37
27
172
1.60
1.46
2.5
2.0
0.00
0.00
estimate
—
5
57
7
28
2.52
1.45
2.6
3.0
17.86
22.51
nmol/l
—
7
23
6
22
2.75
1.44
2.5
1.5
118.83
162.26
mmol/24h
—
6
22
49
357
1.42
1.43
2.9
2.5
10.81
15.46
nmol/l
3.83
44
329
19
111
1.74
1.41
1.4
1.5
17011.17
15151.74
e6/l
0.10
12
82
6
23
2.63
1.37
2.0
2.6
—
—
—
0
0
70
547
1.33
1.34
1.4
1.2
—
—
—
0
0
12
61
1.99
1.34
1.4
1.5
289.43
201.52
u/ml
—
7
29
146
1254
1.24
1.33
1.8
1.7
20.28
20.06
nmol/l
0.06
136
1062
200
1776
1.22
1.32
3.7
3.1
361.93
120.25
ug/l
1.31
187
1660
16
91
1.79
1.30
1.7
1.2
—
—
—
0
0
49
364
1.39
1.30
2.7
1.9
46.36
33.58
u/l
0.62
33
297
10
48
2.11
1.28
2.0
1.9
—
—
—
0
0
117
988
1.25
1.24
4.7
3.9
1.02
1.02
kg/l
0.35
81
646
23
346
0.65
1.23
1.1
1.5
—
—
—
0
0
5
19
2.65
1.22
1.0
1.1
—
—
—
0
0
125
1450
0.81
1.20
3.2
3.4
—
—
—
0
0
22
142
1.58
1.16
1.4
1.2
—
—
—
0
0
54
679
0.77
1.04
1.3
1.3
41.57
11.83
u/ml
0.66
18
262
36
265
1.39
1.03
1.7
1.7
—
—
—
0
0
344
3601
0.83
0.99
4.3
4.5
1.33
1.28
mmol/l
0.64
317
3305
5
23
2.19
0.98
1.4
2.4
56.00
66.67
ug/l
—
5
23
21
303
0.68
0.95
1.5
1.3
—
—
—
0
0
150
1332
1.19
0.95
2.3
2.2
173.01
297.12
u/l
1.14
143
1258
6
27
2.24
0.93
1.0
1.2
—
—
—
0
0
6
28
2.16
0.92
1.2
1.1
2268.17
1724.14
miu/ml
—
6
28
414
4015
1.28
0.91
22.3
10.2
26.12
26.02
u/l
0.04
403
3880
315
2980
1.18
0.89
4.9
4.0
14.97
14.90
pmol/l
0.17
285
2720
205
1879
1.16
0.86
2.1
2.1
88.89
96.80
pmol/l
1.60
123
965
165
1495
1.16
0.80
4.7
4.2
6.01
1.92
ug/l
0.77
149
1341
0
24
0.00
0.79
0.0
1.1
—
10.20
—
0
5
0
24
0.00
0.79
0.0
1.3
—
144.54
—
0
24
8
48
1.68
0.79
1.1
1.1
—
—
—
0
0
353
3663
0.85
0.77
6.5
6.8
39.07
39.76
mmol/mol
0.77
328
3446
9
55
1.65
0.74
1.1
1.1
—
—
—
0
0
7
38
1.85
0.74
1.6
1.5
6.74
8.28
mmol/l
—
7
38
271
2555
1.14
0.73
3.4
3.2
54.62
46.22
u/l
0.86
258
2406
7
41
1.72
0.70
2.3
2.0
—
—
—
0
0
15
102
1.49
0.68
1.3
1.2
3.69
3.95
mmol/l
0.46
15
97
32
250
1.30
0.67
5.3
2.9
0.64
0.63
%
0.10
32
250
32
251
1.30
0.66
5.2
2.9
1.20
1.15
%
0.16
32
251
16
113
1.43
0.62
1.4
1.2
—
—
—
0
0
8
50
1.61
0.61
12.3
3.4
8.34
11.31
%
—
8
50
8
53
1.52
0.58
1.5
1.1
—
—
—
0
0
122
1106
1.14
0.58
5.2
3.3
0.00
0.00
estimate
-0.00
54
307
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
8
54
1.49
0.57
1.8
1.2
—
—
—
0
0
6
36
1.68
0.57
1.3
1.2
—
—
—
0
0
10
65
1.55
0.56
1.6
1.3
44.09
93.93
mu/l
—
10
59
8
124
0.64
0.55
2.4
1.4
—
—
—
0
0
14
100
1.41
0.52
1.2
1.4
—
—
—
0
0
5
81
0.61
0.46
1.2
1.8
—
—
—
0
0
9
131
0.68
0.43
2.3
1.4
—
—
—
0
0
9
131
0.68
0.43
2.2
1.4
—
—
—
0
0
11
150
0.73
0.42
1.5
1.6
—
15.73
—
0
33
17
215
0.78
0.40
1.1
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
15
115
1.31
0.39
4.7
4.8
—
—
—
0
0
10
136
0.73
0.38
6.8
11.0
—
—
—
0
0
8
113
0.70
0.37
1.0
1.1
1.33
1.53
g/l
—
8
113
17
213
0.79
0.37
2.5
2.5
—
—
—
0
0
8
116
0.68
0.37
1.0
1.1
0.90
0.91
g/l
—
8
116
14
108
1.31
0.35
2.3
2.8
0.87
1.71
index
—
8
51
20
163
1.24
0.34
1.9
2.2
397.04
631.48
ug/l
0.33
20
155
92
849
1.10
0.34
3.7
4.2
60.19
437.56
ng/l
3.57
72
669
15
118
1.28
0.34
1.5
1.3
448.47
517.77
mg/l
0.45
15
111
22
182
1.22
0.33
1.5
2.1
1.15
8.57
iu/ml
—
6
44
6
46
1.31
0.33
1.0
1.1
—
—
—
0
0
85
920
0.91
0.33
1.3
1.3
1.43
1.98
u/ml
0.31
24
250
10
132
0.75
0.32
1.4
1.4
—
—
—
0
0
11
83
1.33
0.32
1.3
1.2
—
—
—
0
0
10
131
0.76
0.31
2.1
1.4
—
—
—
0
0
7
100
0.70
0.31
2.6
1.3
—
—
—
0
0
8
63
1.27
0.28
2.4
1.5
—
—
—
0
0
31
272
1.15
0.27
1.4
1.3
551.00
283.99
u/ml
0.27
31
254
139
1459
0.93
0.26
3.7
4.2
14.44
8.20
mg/mmol
0.83
87
923
29
330
0.87
0.26
1.1
1.2
—
—
—
0
0
16
191
0.83
0.25
1.8
1.9
—
—
—
0
0
419
4147
1.10
0.23
50.2
21.5
248.16
245.69
e9/l
0.28
409
4060
419
4148
1.10
0.22
50.1
21.5
4.26
4.53
e12/l
17.84
407
4045
419
4148
1.10
0.22
50.2
21.5
6.86
6.70
e9/l
0.31
408
4047
0
10
0.00
0.21
0.0
8.5
—
25.98
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
8
101
0.79
0.21
1.0
1.1
—
0.67
—
0
13
0
12
0.00
0.21
0.0
1.5
—
9.39
—
0
12
0
13
0.00
0.21
0.0
1.8
—
17.82
—
0
13
138
1436
0.94
0.20
3.2
3.5
116.53
46.19
mg/l
0.86
87
923
6
48
1.25
0.20
1.2
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
36
330
1.10
0.17
2.2
3.6
111.37
201.89
ng/l
1.93
30
304
11
131
0.84
0.17
1.5
1.1
—
—
—
0
0
7
63
1.11
0.17
1.1
1.5
—
—
nmol/l
—
0
0
51
483
1.06
0.12
3.0
2.5
120.30
116.61
ug/g
0.04
40
385
149
1528
0.96
0.12
3.1
3.4
7.38
7.61
mmol/l
0.23
121
1300
85
878
0.96
0.10
2.8
2.9
0.90
0.74
ug/l
0.50
56
558
371
3738
0.96
0.10
5.1
5.3
5.96
6.01
mmol/l
0.29
336
3419
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
60
0.83
0.08
2.4
2.2
1.21
1.20
mmol/l
—
5
60
5
62
0.80
0.08
2.4
2.2
104.40
106.13
mmol/l
—
5
62
5
62
0.80
0.08
2.4
2.2
4.04
4.15
mmol/l
—
5
62
15
163
0.92
0.07
1.1
1.3
—
—
—
0
0
16
149
1.08
0.05
1.8
1.5
1.16
1.16
g/l
0.01
16
140
30
309
0.97
0.02
5.3
2.6
6.28
6.05
ph
0.78
23
210
56
552
1.02
0.01
1.4
1.4
274.29
510.24
titre
1.38
14
123
38
373
1.02
0.01
1.4
1.5
—
—
—
0
0
13
125
1.04
0.00
1.2
1.1
—
—
—
0
0
14
138
1.01
0.00
1.9
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
358
3580
1.00
-0.00
5.8
5.1
1.88
1.93
mu/l
0.30
330
3288
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
35.85
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
0.00
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
0.48
—
0
5
5
50
1.00
-0.00
1.0
1.2
—
—
—
0
0
7
76
0.92
-0.00
1.1
1.5
—
0.59
nmol/l
—
0
9
0
8
0.00
-0.00
0.0
2.0
—
1.17
—
0
8
0
9
0.00
-0.00
0.0
1.4
—
66.67
—
0
9
8
88
0.91
-0.00
3.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.48
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
36.43
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
80.00
—
0
6

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_BONE_CARTILAGE_NAS_WIDE – Malignant neoplasm of bone and articular cartilage of other and unspecified sites, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).