Hepatic failure, not elsewhere classified

K11_HEPFAIL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K72
  • Hospital discharge: ICD-9 570
  • Hospital discharge: ICD-8 570
  • Hospital discharge: excluded ICD-8 57001
  • Cause of death: ICD-10 K72
  • Cause of death: ICD-9 570
  • Cause of death: ICD-8 570
  • Cause of death: excluded ICD-8 57001

2 out of 7 registries used, show all original rules.

1627

4. Check minimum number of events

None

1627

5. Include endpoints

None

1627

6. Filter based on genotype QC (FinnGen only)

1469

Control definitions (FinnGen only)

Control exclude
K11_LIVER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K70-K77
Name in latin
Insufficientia hepatis non alibi classificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13134 5721 7234
Only index persons 9949 4454 5495
Unadjusted period prevalence (%)
Whole population 0.19 0.16 0.20
Only index persons 0.19 0.16 0.21
Median age at first event (years)
Whole population 60.26 60.66 59.96
Only index persons 60.52 60.24 60.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1469 673 796
Unadjusted period prevalence (%) 0.31 0.24 0.36
Median age at first event (years) 61.02 58.39 63.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1502
Matched controls
15020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
34.6
315.6
204
68
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
+∞
313.9
290
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.7
310.5
593
1180
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
10.4
307.7
510
709
R18
ICD-10 Finland
Ascites
40.6
307.7
268
80
C03DA01
ATC
spironolactone; oral
8.2
307.7
592
1106
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
37.6
307.7
241
76
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
307.7
625
*
K72.9
ICD-10 Finland
Hepatic failure, unspecified
5656.5
307.7
681
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
3029.4
282.3
264
*
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
227.0
212
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
9.3
193.6
256
326
A06AD11
ATC
lactulose; oral
5.3
193.5
532
1417
A05AA02
ATC
ursodeoxycholic acid; oral
37.9
191.2
119
34
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
358.5
188.9
187
6
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
21.6
181.5
138
70
127
Kela drug reimbursment
Transplant complication
20.8
177.3
137
72
C03CA01
ATC
furosemide; systemic
4.3
170.8
834
3386
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.3
168.9
784
3065
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
69.9
168.7
92
14
K76.9
ICD-10 Finland
Liver disease, unspecified
92.3
166.0
87
10
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.3
148.7
542
1754
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
6.2
136.4
264
503
L04AA06
ATC
mycophenolic acid; systemic
14.3
131.9
123
93
Z94.4
ICD-10 Finland
Liver transplant status
466.9
131.1
129
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
27.3
130.8
90
35
L04AD02
ATC
tacrolimus; systemic
21.7
122.3
92
45
TK800
NOMESCO Finland
Hemodialysis
10.8
120.4
135
136
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
38.9
120.1
74
20
JJC00
NOMESCO Finland
Allogenic transplantation of liver
+∞
116.2
110
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.5
114.0
245
511
A07AA11
ATC
rifaximin; oral
303.5
111.6
112
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
+∞
105.5
100
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
+∞
102.3
97
*
K83.0
ICD-10 Finland
Cholangitis
14.8
101.3
92
66
JN3AD
NOMESCO Finland
Abdominal CT examination
3.9
100.8
369
1163
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
100.1
506
1965
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
17.2
99.2
83
51
D97
ICPC
Liver disease NOS
34.6
99.0
63
19
K70.1
ICD-10 Finland
Alcoholic hepatitis
+∞
96.9
92
*
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
27.8
93.9
64
24
L04AD01
ATC
ciclosporin; systemic
11.6
91.9
97
89
D64.9
ICD-10 Finland
Anaemia, unspecified
3.7
85.6
321
1019
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
85.2
81
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
419.3
80.7
80
*
K92.0
ICD-10 Finland
Haematemesis
8.2
79.0
108
140
A41.9
ICD-10 Finland
Sepsis, unspecified
6.1
78.5
143
253
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
278.3
78.3
79
*
P15
ICPC
Chronic alcohol abuse
6.9
75.4
121
188
WX872
NOMESCO Finland
Intensive care
4.8
75.3
183
419
UJK02
NOMESCO Finland
ERCP
7.1
68.5
106
158
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
68.2
65
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
8.8
67.9
87
104
JN4AD
NOMESCO Finland
Body CT examination
3.3
67.4
311
1114
N17.8
ICD-10 Finland
Other acute renal failure
10.9
67.0
73
70
A10AB05
ATC
insulin aspart; parenteral
4.0
66.3
212
597
57009
ICD-8 Finland
Acute and subacute necrosis of liver, Unspecified
+∞
65.1
62
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
64.6
924
5824
C07AA05
ATC
propranolol; systemic
2.8
60.2
399
1738
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
9.2
60.0
74
84
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
59.8
57
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
7.9
58.6
82
109
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.4
58.5
121
240
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.7
57.8
113
213
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
57.7
282
1038
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
8.3
57.5
77
97
AA1AD
NOMESCO Finland
CT of head and brain
2.4
57.5
603
3258
F10.20
ICD-10 Finland
Alcohol dependence currently independent
8.1
56.9
78
101
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
7.0
56.0
87
130
WW500
NOMESCO Finland
Blood transfusion
4.8
55.8
133
298
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
55.6
472
2310
K83.1
ICD-10 Finland
Obstruction of bile duct
8.7
54.3
70
84
L04AX01
ATC
azathioprine; systemic
5.0
54.1
121
257
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.8
52.8
85
132
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
52.7
232
801
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
52.2
179
526
C07AG02
ATC
carvedilol; oral
3.9
52.2
167
468
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
6.1
51.8
92
158
K70.0
ICD-10 Finland
Alcoholic fatty liver
95.1
50.2
55
6
I50.9
ICD-10 Finland
Heart failure, unspecified
2.7
50.1
330
1419
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.4
49.7
204
673
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.3
48.9
134
335
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.0
48.9
88
153
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.9
48.7
68
90
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.7
48.6
117
264
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.3
48.3
101
202
F10.24
ICD-10 Finland
Alcohol depence active use
8.1
47.9
65
83
WX892
NOMESCO Finland
Monitored bed care
3.2
46.2
199
675
JJ5AT, ,
NOMESCO Finland
+∞
46.1
44
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
45.9
268
1079
K92.1
ICD-10 Finland
Melaena
3.7
45.8
153
441
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
45.6
253
991
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
237.1
45.2
46
*
A10AE04
ATC
insulin glargine; parenteral
3.0
44.3
225
839
N19
ICD-10 Finland
Unspecified kidney failure
4.3
43.7
117
287
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
42.9
41
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
8.1
42.8
58
74
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.0
42.6
130
351
ZXD05
NOMESCO Finland
Urgent procedure
2.2
42.5
543
3102
WX882
NOMESCO Finland
High dependency care
5.1
42.1
91
187
G93.4
ICD-10 Finland
Encephalopathy, unspecified
80.9
42.1
47
6
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
9.7
41.7
49
52
R50.9
ICD-10 Finland
Fever, unspecified
2.5
40.6
307
1399
TK810
NOMESCO Finland
Hemofiltration
12.0
40.4
41
35
A41.8
ICD-10 Finland
Other specified sepsis
6.0
40.3
72
124
N07BB01
ATC
disulfiram; oral
4.2
40.2
112
283
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
210.6
40.0
41
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.1
39.7
86
177
B18.2
ICD-10 Finland
Chronic viral hepatitis C
9.9
39.6
46
48
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
9.7
39.0
46
49
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
12.1
38.6
39
33
Z51.5
ICD-10 Finland
Palliative care
2.8
37.4
209
818
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
37.4
594
3644
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
6.9
37.1
58
87
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.7
36.6
121
345
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.6
35.4
121
353
ZX120
NOMESCO Finland
Intravenous
2.8
35.2
199
782
N02AA05
ATC
oxycodone; systemic
2.2
34.9
373
1960
P19
ICPC
Drug abuse
14.2
34.9
32
23
UJF32
NOMESCO Finland
Coloscopy
2.1
34.9
474
2733
N02AX02
ATC
tramadol; systemic, rectal
2.0
34.7
742
5008
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
6.8
34.6
55
84
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
34.5
33
*
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
34.5
33
*
R11
ICD-10 Finland
Nausea and vomiting
2.8
33.9
183
701
A02BC02
ATC
pantoprazole; systemic
2.1
33.0
1093
8496
57008
ICD-8 Finland
Acute and subacute necrosis of liver, Alii definiti
+∞
32.4
31
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
13.2
32.3
31
24
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
5.0
32.3
71
148
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
32.2
483
2870
I50.0
ICD-10 Finland
Congestive heart failure
2.8
32.2
172
655
H02AB04
ATC
methylprednisolone; systemic
2.4
31.8
266
1258
F05.9
ICD-10 Finland
Delirium, unspecified
5.1
31.7
67
135
ZX108
NOMESCO Finland
Inhalation
9.7
31.6
37
39
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
8.4
31.3
41
50
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
31.2
489
2944
J01MA02
ATC
ciprofloxacin; systemic
1.9
30.3
654
4370
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
8.2
30.0
40
50
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
29.8
100
288
R41.0
ICD-10 Finland
Disorientation, unspecified
4.0
29.7
86
223
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.0
29.6
142
509
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.4
29.5
228
1039
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.1
29.3
63
129
A46
ICD-10 Finland
Erysipelas
2.2
29.0
289
1466
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
28.9
226
1035
Z2446
NOMESCO Finland
Social worker
3.0
28.8
139
500
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
28.3
440
2626
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
28.2
153
586
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
27.8
28.1
38
14
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
6.4
28.0
47
76
E87.5
ICD-10 Finland
Hyperkalaemia
5.1
27.9
59
119
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.9
27.8
30
28
A28
ICPC
Limited function/disability NOS
2.1
27.7
337
1844
P16
ICPC
Acute alcohol abuse
5.7
27.2
51
92
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.2
27.2
57
114
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
27.2
26
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
27.1
149
575
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
27.0
199
886
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.6
26.9
91
263
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
8.7
26.7
34
40
I81
ICD-10 Finland
Portal vein thrombosis
25.2
26.6
37
15
N05CF01
ATC
zopiclone; oral
1.9
26.6
529
3408
J01MA12
ATC
levofloxacin; systemic
2.0
26.5
335
1854
R4110
NOMESCO Finland
Physiotherapy
1.9
26.4
469
2916
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
5.8
26.1
48
85
E87.6
ICD-10 Finland
Hypokalaemia
3.6
25.9
88
255
H02AB06
ATC
prednisolone; systemic
1.8
25.9
752
5416
K29.6
ICD-10 Finland
Other gastritis
6.5
25.7
42
66
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.8
25.4
78
211
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.0
25.3
45
77
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
5.7
25.3
47
84
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
25.1
24
*
K76.6
ICD-10 Finland
Portal hypertension
+∞
25.1
24
*
N05BA04
ATC
oxazepam; oral
1.9
25.0
424
2588
JN4BD
NOMESCO Finland
Extensive body CT
2.3
25.0
202
935
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
24.9
293
1577
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
24.8
548
3629
N06AX11
ATC
mirtazapine; oral
1.8
24.8
543
3588
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
24.8
345
1972
UJD02
NOMESCO Finland
Gastroscopy
3.1
24.5
104
347
WX730
NOMESCO Finland
Conventional respirator
5.5
24.4
47
87
N05AH04
ATC
quetiapine; oral
2.1
24.2
288
1555
L04AA01
ATC
[U] ciclosporin
6.5
24.0
39
61
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.8
23.9
73
197
JN4CD
NOMESCO Finland
Very extensive body CT
3.4
23.8
87
265
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.6
23.4
33
44
WX002
NOMESCO Finland
Sedation and analgesia
2.0
23.3
332
1908
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
4.7
23.2
54
118
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
23.0
22
*
K86.1
ICD-10 Finland
Other chronic pancreatitis
7.2
22.9
34
48
A10AE05
ATC
insulin detemir; parenteral
2.9
22.9
111
400
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.6
22.5
43
79
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
22.5
90
290
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.6
22.5
134
538
N18.8
ICD-10 Finland
Other chronic renal failure
4.3
22.5
58
138
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
22.4
85
265
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
22.0
132
531
Z3231
NOMESCO Finland
Registered nurse
1.8
21.9
440
2811
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
21.9
196
946
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.6
21.8
35
54
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
6.6
21.8
35
54
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.7
21.3
34
52
XW000
NOMESCO Finland
Bone marrow biopsy
3.1
21.0
92
313
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
20.8
362
2211
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
5.6
20.6
39
71
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
6.2
20.4
35
58
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
20.3
230
1214
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
20.1
236
1261
R94.5
ICD-10 Finland
Abnormal results of liver function studies
6.0
20.0
35
59
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
20.0
273
1539
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.7
20.0
111
430
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
19.9
410
2628
A10AC01
ATC
insulin (human); parenteral
2.4
19.8
141
615
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
19.8
407
2607
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.4
19.7
71
214
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
19.7
273
1546
Z3226
NOMESCO Finland
Physiotherapist
1.9
19.6
295
1716
S97
ICPC
Chronic ulcer skin
2.5
19.6
129
543
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
4.9
19.5
43
90
K29.7
ICD-10 Finland
Gastritis, unspecified
3.2
19.4
78
252
V03AE01
ATC
polystyrene sulfonate; oral
5.2
19.4
40
79
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.0
19.3
87
301
ZXE90
NOMESCO Finland
More than 22 hours
8.0
19.2
26
33
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
6.8
19.2
30
45
R60.9
ICD-10 Finland
Oedema, unspecified
2.7
19.0
109
429
A98
ICPC
Health maint/preventive medicine
0.5
19.0
1210
13310
Z72.1
ICD-10 Finland
Alcohol use
5.0
18.8
40
81
N05BA01
ATC
diazepam; systemic, rectal
2.0
18.8
215
1137
SPAT1254
SPAT
Administration of medicine
2.0
18.8
240
1320
L28
ICPC
Limited function/disability (L)
1.8
18.7
320
1937
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.9
18.4
33
57
SPAT1262
SPAT
Handing over of treatment supplies
1.9
18.2
282
1652
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
18.2
502
3471
M04AA01
ATC
allopurinol; systemic
2.0
18.1
234
1292
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.9
18.1
53
139
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.6
18.0
108
435
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
5.9
17.9
32
55
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.1
17.9
182
920
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.2
17.9
37
73
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.3
17.8
135
606
T90
ICPC
Diabetes non-insulin dependent
1.7
17.8
401
2625
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
67.4
17.7
20
*
K76.89
ICD-10 Finland
Other specified diseases of liver
+∞
17.7
17
*
57309
ICD-8 Finland
Other diseases of liver, Unspecified
+∞
17.7
17
*
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.6
17.4
59
171
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
18.9
17.3
26
14
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
5.2
17.3
35
68
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.6
17.2
56
158
J01FF01
ATC
clindamycin; systemic
1.7
17.2
413
2747
OAB43, ,
SPAT
0.4
17.2
115
2417
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
3.5
16.8
58
170
JAH00
NOMESCO Finland
Laparotomy
3.4
16.8
61
185
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
5.5
16.7
32
59
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
35.5
16.7
21
6
K65.0
ICD-10 Finland
Acute peritonitis
5.9
16.7
30
52
A10BH05
ATC
linagliptin; oral
2.6
16.5
98
392
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
16.1
245
1425
A40.8
ICD-10 Finland
Other streptococcal sepsis
5.2
16.0
33
65
B01AA03
ATC
warfarin; systemic
1.7
16.0
315
1979
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
15.9
97
393
N05CD07
ATC
temazepam; oral
2.0
15.9
196
1062
N06AB04
ATC
citalopram; systemic
1.8
15.9
308
1925
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.5
15.7
54
158
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.6
15.7
37
82
A02BC01
ATC
omeprazole; systemic
1.7
15.6
410
2778
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
15.5
104
441
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
15.5
133
629
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
4.8
15.4
35
75
E86
ICD-10 Finland
Volume depletion
3.3
15.3
57
176
A10BH01
ATC
sitagliptin; oral
2.1
15.2
163
839
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
13.2
15.2
26
20
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
15.2
543
3962
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
15.1
598
4465
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
15.1
157
800
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.8
15.0
45
120
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
14.9
272
1667
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
32.0
14.8
19
6
3AC01, ,
NOMESCO Finland
6.0
14.8
26
44
SPAT1265
SPAT
Breathalyser
5.6
14.8
28
51
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
14.8
131
2501
A07EA06
ATC
budesonide; oral, local oral
3.0
14.7
67
233
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
5.4
14.7
29
55
N03AX14
ATC
levetiracetam; systemic
3.2
14.7
59
191
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.9
14.6
71
256
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
14.6
14
*
57300
ICD-8 Finland
Other diseases of liver, Hepatitis NUD
+∞
14.6
14
*
N06AX16
ATC
venlafaxine; oral
1.9
14.6
204
1152
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
5.9
14.5
26
45
R53
ICD-10 Finland
Malaise and fatigue
1.6
14.5
376
2535
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
14.5
274
1697
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.0
14.4
64
220
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.3
14.3
55
173
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.4
14.3
51
153
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.5
14.3
95
402
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.9
14.2
66
232
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
13.5
14.2
24
18
C10AC01
ATC
colestyramine; oral
3.4
14.2
52
159
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
14.6
14.1
23
16
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
3.5
14.0
49
145
WX419
NOMESCO Finland
Other general anesthesy
5.9
14.0
25
43
J94.8
ICD-10 Finland
Other specified pleural conditions
4.2
14.0
37
90
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
14.0
239
1436
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
13.9
106
477
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.4
13.8
34
78
C07AB07
ATC
bisoprolol; oral
1.5
13.8
754
5998
C01AA05
ATC
digoxin; systemic
2.1
13.8
142
721
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
13.6
380
2601
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
10.2
13.5
26
26
R60.0
ICD-10 Finland
Localized oedema
1.8
13.5
204
1181
Z94.0
ICD-10 Finland
Kidney transplant status
5.1
13.4
28
56
B01AB05
ATC
enoxaparin; parenteral
1.6
13.3
469
3387
A07AA09
ATC
vancomycin; oral
4.5
13.3
32
72
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
13.2
215
1271
RS220, ,
NOMESCO Finland
4.6
13.1
31
69
198
Kela drug reimbursment
Sorafenib
28.6
13.0
17
6
R40.2
ICD-10 Finland
Coma, unspecified
5.7
12.9
24
43
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
12.9
120
586
E66.8
ICD-10 Finland
Other obesity
2.5
12.9
81
334
TJA10
NOMESCO Finland
Laparocentesis
14.2
12.8
21
15
SPAT1263
SPAT
Sampling
1.5
12.7
574
4367
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.2
12.7
49
155
Z2221
NOMESCO Finland
Medical doctor
1.6
12.6
386
2694
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.7
12.5
70
272
K71.1
ICD-10 Finland
Toxic liver disease with hepatic necrosis
+∞
12.5
12
*
57000
ICD-8 Finland
Acute and subacute necrosis of liver, Hepatitis acuta degenerativa
+∞
12.5
12
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.6
12.4
41
117
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.6
12.4
29
64
N05BA02
ATC
chlordiazepoxide; systemic
3.2
12.3
49
158
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.8
12.3
62
229
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.4
12.2
82
348
H02AB09
ATC
hydrocortisone; systemic
3.3
12.2
46
143
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.3
12.2
45
138
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.0
12.2
34
86
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.8
12.2
62
230
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.5
12.1
78
325
T89
ICPC
Diabetes insulin dependent
2.6
12.1
69
271
N05AH03
ATC
olanzapine; systemic
2.3
12.1
97
446
Z72.2
ICD-10 Finland
Drug use
18.2
12.1
18
10
2BD01, ,
NOMESCO Finland
21.5
12.0
17
8
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
4.0
12.0
33
83
B01AB04
ATC
dalteparin; parenteral
2.4
11.9
84
365
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.0
11.9
51
172
A10BB12
ATC
glimepiride; oral
2.1
11.8
115
571
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
14.8
11.8
19
13
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
3.8
11.8
35
93
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
11.8
72
293
N03AX16
ATC
[U] pregabalin
1.6
11.7
334
2291
SPAT1216
SPAT
Assessment of functional ability
1.7
11.6
239
1509
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
19.1
11.6
17
9
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
5.3
11.6
23
44
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.7
11.5
36
99
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.6
11.5
66
260
SPAT1255
SPAT
Intravenous administration of medicine
2.1
11.5
111
549
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
10.1
11.5
22
22
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
11.5
11
*
WW408, ,
NOMESCO Finland
+∞
11.5
11
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
4.4
11.5
28
64
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
5.4
11.4
22
41
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
10.6
11.3
21
20
L04AA05
ATC
[U] tacrolimus
35.3
11.3
14
*
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
3.7
11.3
35
96
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.2
409
2958
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.2
330
2276
E000001, ,
ATC
1.6
11.2
265
1734
R4190
NOMESCO Finland
Nutritional therapy
2.5
11.2
69
282
K85.8
ICD-10 Finland
Other acute pancreatitis
5.6
11.2
21
38
OAA67, ,
SPAT
0.4
11.1
52
1285
RS221, ,
NOMESCO Finland
3.9
11.1
32
83
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
11.1
183
1084
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
11.1
342
2382
I50.1
ICD-10 Finland
Left ventricular failure
2.2
11.0
91
424
3A064, ,
NOMESCO Finland
14.0
11.0
18
13
JJA20
NOMESCO Finland
Open biopsy of liver
14.0
11.0
18
13
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.7
10.9
60
232
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.2
10.8
96
460
ZY010
NOMESCO Finland
Hospital outpatient
2.4
10.8
76
330
K81.9
ICD-10 Finland
Cholecystitis, unspecified
5.0
10.7
23
47
F61.0
ICD-10 Finland
Mixed personality disorders
4.2
10.6
28
68
3A422, ,
NOMESCO Finland
60.4
10.6
12
*
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.5
10.6
36
105
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
5.3
10.6
21
40
N05BA12
ATC
alprazolam; oral
1.9
10.6
144
804
K77
ICPC
Heart failure
3.0
10.6
45
151
K86.3
ICD-10 Finland
Pseudocyst of pancreas
11.3
10.6
19
17
N30.0
ICD-10 Finland
Acute cystitis
1.7
10.5
227
1448
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
10.5
56
213
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
10.5
165
964
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
10.5
100
493
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
10.4
10
*
I86.4
ICD-10 Finland
Gastric varices
+∞
10.4
10
*
UJK12
NOMESCO Finland
Peroral cholangioscopy
32.8
10.3
13
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.3
10.3
76
337
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.2
10.3
91
435
S01.0
ICD-10 Finland
Open wound of scalp
1.9
10.3
133
730
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.4
10.3
67
281
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
4.1
10.2
28
70
B03XA02
ATC
darbepoetin alfa; parenteral
2.9
10.2
47
165
N06AB10
ATC
escitalopram; oral
1.6
10.2
258
1715
C10AA07
ATC
rosuvastatin; oral
0.6
10.1
264
3785
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.5
10.1
65
271
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
5.3
10.1
20
38
UJC12
NOMESCO Finland
Flexible oesophagoscopy
5.1
10.1
21
42
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.8
10.0
49
178
A11CC03
ATC
alfacalcidol; systemic
2.9
10.0
45
156
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
4.7
10.0
23
50
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.4
10.0
71
310
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
40.3
10.0
12
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.9
10.0
29
76
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.4
10.0
69
298
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.6
9.9
58
231
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.0
9.9
44
152
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
8.8
9.8
20
23
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
10.7
9.8
18
17
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.2
9.7
78
359
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
7.4
9.7
22
30
K08.3
ICD-10 Finland
Retained dental root
1.9
9.7
126
694
R77.0
ICD-10 Finland
Abnormality of albumin
55.4
9.7
11
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.0
9.6
106
551
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.7
9.6
49
182
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.8
9.6
29
78
SPAT1240
SPAT
Therapeutic discussion
1.9
9.6
127
703
A04
ICPC
Weakness/tiredness general
1.6
9.6
221
1433
J96.0
ICD-10 Finland
Acute respiratory failure
3.7
9.6
30
83
K07
ICPC
Swollen ankles/oedema
2.2
9.5
80
375
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
15.1
9.5
15
10
N05AF03
ATC
chlorprothixene; systemic
3.0
9.5
41
139
N05AA02
ATC
levomepromazine; systemic
2.4
9.5
64
273
A10BA02
ATC
metformin; oral
1.5
9.5
424
3180
J01DB01
ATC
cefalexin; oral
1.5
9.4
1176
10601
N06AB06
ATC
sertraline; oral
1.8
9.4
150
879
B17.8
ICD-10 Finland
Other specified acute viral hepatitis
100.7
9.4
10
*
K70
ICD-10 Finland
Alcoholic liver disease
100.7
9.4
10
*
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
7.6
9.4
21
28
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
9.4
146
849
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
17.6
9.4
14
8
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
+∞
9.4
9
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
9.4
9
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
12.4
9.4
16
13
RS120, ,
NOMESCO Finland
12.4
9.4
16
13
A12BA01
ATC
potassium chloride; oral
2.3
9.3
72
326
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.2
9.3
74
339
ZXE00
NOMESCO Finland
One hour or less
1.4
9.3
530
4153
E83.1
ICD-10 Finland
Disorders of iron metabolism
10.7
9.3
17
16
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.1
9.3
92
461
B03BA03
ATC
hydroxocobalamin; parenteral
2.1
9.2
88
434
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.2
9.1
36
116
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
4.8
9.1
20
42
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
9.1
193
1226
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
9.0
269
1852
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
10.1
9.0
17
17
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.2
9.0
35
112
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.0
8.9
92
467
G41.9
ICD-10 Finland
Status epilepticus, unspecified
7.5
8.9
20
27
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
8.9
269
1857
A07EC02
ATC
mesalazine; oral, rectal
2.2
8.9
77
366
D64.8
ICD-10 Finland
Other specified anaemias
3.1
8.9
37
123
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.5
8.9
53
214
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
9.5
8.8
17
18
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.1
8.7
36
119
2BB01, ,
NOMESCO Finland
50.3
8.7
10
*
205
Kela drug reimbursment
Chronic hypertension
1.5
8.7
392
2938
H26.3
ICD-10 Finland
Drug-induced cataract
6.6
8.7
21
32
UJF92
NOMESCO Finland
Capsular endoscopy
3.0
8.6
36
120
A08
ICPC
Swelling
2.0
8.6
92
474
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.8
8.6
42
153
SPAT1247
SPAT
Outpatient detoxication and monitoring
11.6
8.6
15
13
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
11.6
8.6
15
13
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
8.6
189
1211
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
16.4
8.6
13
8
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
8.5
68
313
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
6.4
8.5
21
33
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
27.7
8.5
11
*
SPAT1229
SPAT
Assessment of need for aid
1.9
8.5
112
620
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
8.4
104
563
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.7
8.4
45
172
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.8
8.4
42
155
GBB00
NOMESCO Finland
Tracheostomy
3.8
8.4
25
67
N06AX17
ATC
milnacipran; oral
4.0
8.3
23
58
K72
ICD-10 Finland
Hepatic failure, not elsewhere classified
+∞
8.3
8
*
K76.1
ICD-10 Finland
Chronic passive congestion of liver
+∞
8.3
8
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
8.3
8
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
+∞
8.3
8
*
57308
ICD-8 Finland
Other diseases of liver, Alii definiti
+∞
8.3
8
*
5CM18, ,
NOMESCO Finland
8.6
8.3
17
20
E66.00
ICD-10 Finland
Metabolic syndrome
2.0
8.3
86
438
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
9.5
8.3
16
17
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
7.1
8.3
19
27
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.2
495
3900
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.2
8.2
71
338
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.9
8.2
109
605
M10.9
ICD-10 Finland
Gout, unspecified
1.8
8.2
114
642
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.4
8.2
55
235
N06AB03
ATC
fluoxetine; oral
1.7
8.2
162
1010
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.1
8.2
33
108
N30.2
ICD-10 Finland
Other chronic cystitis
4.8
8.1
18
38
E0000UV, ,
ATC
1.4
8.1
549
4409
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
8.2
8.1
17
21
N05AB01
ATC
dixyrazine; systemic
3.8
8.1
24
64
JDA22
NOMESCO Finland
Endoscopic ligature of varices of stomach
33.5
8.1
10
*
XF612
NOMESCO Finland
Measurement of central venous pressure
17.3
8.1
12
7
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
11.8
8.1
14
12
SPAT1272
SPAT
Drug screening
11.8
8.1
14
12
160
Kela drug reimbursment
exenatide
2.9
8.0
36
125
WX704
NOMESCO Finland
Intubation
1.8
8.0
116
662
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.9
207
1381
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
7.9
340
2518
A02BC05
ATC
esomeprazole; systemic
1.4
7.9
547
4404
I50
ICD-10 Finland
Heart failure
2.4
7.9
54
233
W19
ICD-10 Finland
Unspecified fall
1.7
7.9
142
863
D05AX52
ATC
calcipotriol, combinations; topical
2.1
7.8
75
371
RD210, ,
NOMESCO Finland
3.2
7.8
30
95
K80.8
ICD-10 Finland
Other cholelithiasis
3.0
7.8
33
111
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
10.9
7.8
14
13
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.6
7.8
213
3049
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
9.5
7.8
15
16
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.1
7.8
76
379
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.6
7.7
25
71
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.7
7.7
39
145
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
4.4
7.7
19
44
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.0
7.7
33
112
N06AB05
ATC
paroxetine; oral
2.0
7.7
77
388
PA2AD
NOMESCO Finland
CT angiography of brain
4.5
7.7
18
40
WW200, ,
SPAT
0.7
7.6
235
3285
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
4.0
7.6
21
53
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.5
7.6
46
187
D07AC01
ATC
betamethasone; topical
1.4
7.6
484
3838
Z02.7
ICD-10 Finland
Issue of medical certificate
1.8
7.6
106
597
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
8.1
7.6
16
20
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
11.9
7.6
13
11
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
11.9
7.6
13
11
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.1
7.6
30
97
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
8.9
7.5
15
17
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
7.5
117
681
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
7.5
101
562
F41.00
ICD-10 Finland
Moderate panic disorder
3.8
7.5
22
58
N06AX26
ATC
vortioxetine; oral
1.9
7.5
93
504
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.0
7.5
84
440
ZY000
NOMESCO Finland
Hospital inpatient
3.7
7.5
23
63
WW200
NOMESCO Finland
Immunization
2.6
7.5
42
165
D07AD01
ATC
clobetasol; topical
1.5
7.5
216
1475
OAA62, ,
SPAT
0.2
7.4
8
374
474, ,
NOMESCO Finland
80.5
7.4
8
*
RS321, ,
NOMESCO Finland
80.5
7.4
8
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.4
7.4
49
208
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.4
7.4
26
78
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
7.4
135
823
S72.0
ICD-10 Finland
Fracture of neck of femur
2.1
7.4
68
332
NB6AA
NOMESCO Finland
Humerus X-ray examination
2.7
7.4
38
143
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.3
224
1547
H02AB07
ATC
prednisone; oral
1.6
7.3
182
1201
F13.24
ICD-10 Finland
Addiction relationship caused by sedative and hypnotic active addiction
10.9
7.3
13
12
I85
ICD-10 Finland
Oesophageal varices
+∞
7.3
7
*
5700A
ICD-9 Finland
Acute and subacute necrosis of liver[NECROSIS HEPATIS TOXICA ACUTA, SINE COMATE HEPATICO]
+∞
7.3
7
*
OAA80, ,
SPAT
0.3
7.3
24
698
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.7
7.3
136
835
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
7.2
97
540
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
7.2
131
797
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.7
7.2
133
813
K86.0
ICD-10 Finland
Alcohol-induced chronic pancreatitis
30.2
7.2
9
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
20.1
7.1
10
5
B17.1
ICD-10 Finland
Acute hepatitis C
20.1
7.1
10
5
K50.8
ICD-10 Finland
Other Crohn disease
3.5
7.1
24
70
JKA20
NOMESCO Finland
Cholecystectomy
2.5
7.1
43
175
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.0
7.1
74
378
L01BB02
ATC
mercaptopurine; oral
4.1
7.1
19
47
ZXD35
NOMESCO Finland
Usual procedure
2.3
7.1
50
219
P03
ICPC
Feeling depressed
1.8
7.1
108
626
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.8
7.1
109
634
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
2.8
7.1
35
129
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.8
7.0
100
567
S76
ICPC
Skin infection other
1.9
7.0
82
436
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
10.1
7.0
13
13
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
10.1
7.0
13
13
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
10.1
7.0
13
13
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.4
7.0
24
71
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.0
503
4059
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.0
142
892
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
6.4
6.9
17
27
A10AB04
ATC
insulin lispro; parenteral
2.4
6.9
46
196
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
5.9
6.9
18
31
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.4
6.9
45
190
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.0
6.9
19
48
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
6.9
174
1153
M01AH05
ATC
etoricoxib; oral
0.7
6.8
633
7404
P29
ICPC
Psychological sympt/compl other
1.9
6.8
84
455
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
4.1
6.8
18
44
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
11.0
6.8
12
11
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.7
184
1240
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
6.7
112
666
WVA20
NOMESCO Finland
Medicine administration
2.4
6.7
46
199
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
7.8
6.6
14
18
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
7.8
6.6
14
18
V03AE02
ATC
sevelamer; oral
7.8
6.6
14
18
F11.20
ICD-10 Finland
Addiction-induced dependence caused by opiates currently independent
12.3
6.6
11
9
Z08
ICPC
Social welfare problem
3.3
6.6
24
74
K85
ICD-10 Finland
Acute pancreatitis
3.0
6.6
28
95
L76
ICPC
Fracture: other
2.3
6.5
48
214
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.5
496
4027
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
6.2
6.5
16
26
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.3
6.4
23
70
TPX15
NOMESCO Finland
Removal of vascular injection port
7.4
6.4
14
19
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.4
148
959
J01MA14
ATC
moxifloxacin; systemic
1.7
6.4
127
792
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
14.4
6.4
10
7
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.3
6.4
44
191
SPAT1227
SPAT
Substance abuse rehabilitation
6.6
6.3
15
23
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.2
6.3
53
250
SPAT1260
SPAT
Consultation of another employee
1.5
6.3
222
1578
D10
ICPC
Vomiting
2.0
6.3
65
332
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.1
6.3
59
291
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
18.1
6.3
9
5
D72
ICPC
Viral hepatitis
18.1
6.3
9
5
B81
ICPC
Anaemia vit B12/folate deficiency
2.1
6.3
56
271
Z944, K720,
ICD-10 Finland
+∞
6.3
6
*
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
6.3
6
*
K74
ICD-10 Finland
Fibrosis and cirrhosis of liver
+∞
6.3
6
*
GBB03
NOMESCO Finland
Percutaneous tracheostomy
+∞
6.3
6
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
6.2
130
821
N06AX03
ATC
mianserin; oral
2.0
6.2
65
333
323
Kela drug reimbursment
Sorafenib
26.8
6.2
8
*
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
26.8
6.2
8
*
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
5.0
6.2
18
36
E87.2
ICD-10 Finland
Acidosis
6.3
6.2
15
24
A10BG03
ATC
pioglitazone; oral
2.4
6.2
40
169
JLC30
NOMESCO Finland
Pancreatoduodenectomy
5.4
6.2
17
32
XPX08
NOMESCO Finland
Intraoperative flow measurement
3.4
6.1
21
62
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.5
6.1
38
157
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.3
6.1
45
201
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.9
6.1
28
99
R06AE07
ATC
cetirizine; oral
1.3
6.1
541
4482
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
4.1
6.1
16
39
WX890
NOMESCO Finland
Intesive care monitoring
4.1
6.1
16
39
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.0
6.1
64
329
742, ,
NOMESCO Finland
12.6
6.1
10
8
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
10.1
6.0
11
11
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
10.1
6.0
11
11
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.3
6.0
44
196
R60.1
ICD-10 Finland
Generalized oedema
5.2
6.0
17
33
A10BX07
ATC
[U] liraglutide
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
264
161
19.68
322.53
1.2
1.1
—
—
—
0
0
517
696
10.80
307.65
1.9
1.9
1.50
1.37
g/l
0.46
486
638
237
62
45.20
307.65
1.1
1.1
—
—
—
0
0
270
168
19.37
307.65
1.2
1.1
—
—
—
0
0
786
1219
12.43
307.65
5.9
2.0
0.16
0.21
g/l
47.08
709
1134
465
222
29.89
307.65
1.5
1.1
119.80
87.37
titre
0.47
51
19
560
905
9.27
307.65
2.9
3.0
12.49
10.58
g/l
9.73
532
831
614
243
42.05
307.65
8.3
1.8
48.21
29.98
umol/l
16.48
593
210
228
114
23.40
304.31
1.2
1.1
1.66
1.45
g/l
5.81
210
104
190
67
32.32
288.30
2.4
1.1
—
—
—
0
0
159
27
65.74
288.09
2.2
1.2
457.45
1588.33
e6/l
1.42
110
21
632
1475
6.67
278.31
10.8
2.5
32.37
7.61
umol/l
25.07
598
1315
562
1251
6.58
257.79
1.8
1.6
—
—
—
0
0
137
20
75.27
254.05
2.2
1.2
—
—
—
0
0
137
22
68.42
250.16
1.5
1.0
9.20
17.80
g/l
2.95
89
17
562
1297
6.33
246.97
13.9
7.5
11.67
10.00
mmol/l
4.13
544
1246
609
1532
6.00
243.12
1.7
1.6
—
—
—
0
0
131
25
57.31
231.67
2.2
1.2
13789.91
5895.31
e6/l
0.49
70
16
127
24
57.71
224.94
2.2
1.2
—
—
—
0
0
139
48
31.81
211.39
1.1
1.0
293.91
291.07
mg/l
0.08
130
43
140
54
28.49
205.11
1.8
2.0
142.32
98.74
umol/l
0.43
62
34
223
219
11.78
204.61
1.3
1.3
271.19
231.41
u/ml
0.82
144
124
316
503
7.69
197.70
3.2
1.6
0.41
0.34
mg/l
0.81
153
242
627
1966
4.76
185.10
3.5
2.7
27.44
22.35
%
7.40
597
1831
218
239
10.50
184.63
1.4
1.5
—
—
—
0
0
616
1912
4.77
184.09
10.5
6.0
1.08
1.04
mmol/l
2.00
593
1776
562
1640
4.88
181.29
1.6
1.3
416.71
478.33
titre
0.42
146
336
647
2123
4.60
179.08
3.5
2.6
2.10
2.29
g/l
9.39
606
1968
116
38
33.00
178.98
3.9
1.9
0.59
0.61
mmol/l
1.21
116
38
663
2283
4.41
170.62
3.6
2.7
12.97
12.76
umol/l
0.26
634
2128
243
339
8.36
169.74
1.3
1.3
—
—
—
0
0
667
2383
4.24
161.59
7.6
3.4
0.78
0.82
mmol/l
11.33
643
2259
137
88
17.03
160.96
1.4
1.1
175.63
88.57
titre
0.55
16
14
946
4334
4.20
160.01
12.4
3.0
93.36
32.15
u/l
11.62
911
4094
192
217
10.00
158.40
1.4
1.5
144.28
151.38
au/ml
0.23
50
58
246
396
7.23
150.64
6.0
2.5
2.66
3.67
g/l
16.38
238
377
889
4208
3.73
136.23
5.9
2.6
63.39
80.47
u/l
0.43
857
3909
1100
6035
4.07
133.25
16.1
5.0
31.07
35.51
g/l
82.05
1069
5656
846
3951
3.61
130.86
7.2
4.4
—
—
—
0
0
99
50
21.13
129.91
45.4
40.4
6.95
7.16
ug/l
0.29
93
45
347
880
4.83
129.18
1.5
1.5
—
—
—
0
0
294
654
5.35
127.86
2.0
1.9
1.10
1.56
g/l
11.01
226
581
1124
6430
3.97
123.72
29.4
16.0
1.41
1.28
inr
11.85
1010
5380
1182
7044
4.18
121.11
25.2
6.4
33.04
11.38
umol/l
43.91
1157
6735
575
2187
3.64
120.94
4.4
2.1
32.10
29.63
s
10.58
559
2125
88
41
22.74
119.33
34.3
28.6
128.42
125.90
ug/l
0.07
74
32
80
29
29.08
118.98
1.0
1.2
—
—
—
0
0
609
2439
3.52
117.56
1.9
1.5
4.04
2.41
g/l
26.77
517
1420
173
247
7.79
117.27
1.3
1.2
—
—
—
0
0
228
447
5.83
113.47
6.0
3.1
1.79
1.57
mg/l
2.80
219
403
80
35
24.09
111.14
1.6
5.7
—
—
—
0
0
438
1488
3.74
107.78
7.5
3.6
7.38
7.38
ph
0.11
284
862
208
410
5.73
102.57
4.7
2.4
60.27
91.88
%
30.95
201
398
426
1478
3.63
100.80
6.9
3.5
5.39
5.84
kpa
15.16
409
1436
511
1993
3.37
100.38
3.4
2.1
—
—
—
0
0
713
3399
3.09
99.01
17.8
4.0
68.65
88.18
%
54.60
702
3332
415
1436
3.61
98.34
7.0
3.5
0.75
1.80
mmol/l
4.36
339
1217
450
1652
3.46
97.06
3.2
2.7
2.50
1.77
%
12.72
411
1482
109
110
10.61
96.85
1.5
1.1
—
—
—
0
0
383
1287
3.65
94.55
3.4
2.7
84.88
68.92
e9/l
6.59
300
949
68
31
22.93
92.79
1.0
1.0
—
—
—
0
0
67
30
23.33
92.07
1.0
1.1
—
—
—
0
0
714
3527
2.95
91.05
3.3
2.3
3.51
2.88
mg/l
6.35
654
3011
223
523
4.83
89.66
3.3
3.5
123.27
2936.71
u/ml
0.86
196
454
60
26
24.00
83.42
1.0
1.2
921.05
1133.33
titre
—
19
6
284
849
3.89
82.50
7.2
3.7
23.03
24.18
mmol/l
5.82
279
841
822
4540
2.79
82.34
10.5
6.2
—
—
—
0
0
102
125
8.68
78.11
1.2
1.2
—
—
—
0
0
104
131
8.46
77.89
2.3
2.5
35.75
44.66
iu/ml
—
10
20
352
1262
3.34
77.02
5.2
2.4
35.77
42.99
u/l
0.86
312
1071
349
1263
3.30
75.03
22.0
9.9
—
—
—
0
0
1043
6862
2.70
68.19
18.9
7.6
1.19
1.21
mmol/l
16.59
939
5921
350
1337
3.11
68.07
18.8
8.5
2.32
1.32
mmol/l
8.60
340
1310
113
184
6.56
67.20
1.6
1.8
0.91
0.83
g/l
0.19
88
147
968
6182
2.59
66.64
18.2
7.1
1.18
1.21
mmol/l
21.74
937
5709
82
94
9.17
66.07
2.3
1.3
0.67
1.21
promille
1.90
72
73
403
1709
2.86
64.54
21.1
8.9
11.54
12.06
kpa
1.68
387
1650
403
1709
2.86
64.54
21.1
8.9
4.76
5.12
kpa
9.54
386
1648
114
197
6.18
63.87
7.2
6.6
12.87
12.02
mg/l
0.84
104
183
400
1701
2.84
63.61
21.3
8.9
7.42
7.41
ph
0.23
226
956
396
1692
2.82
62.26
21.0
8.9
-0.24
0.97
mmol/l
4.21
322
1406
190
518
4.05
62.04
3.2
2.2
1415.01
458.42
ug/l
1.24
179
489
352
1421
2.93
61.45
3.5
4.3
9.52
21.57
ug/l
0.97
304
1169
186
503
4.08
61.39
4.1
2.1
23.96
21.15
s
6.78
175
462
370
1540
2.86
60.99
21.8
9.3
95.88
95.50
%
0.78
362
1499
957
6235
2.47
60.59
11.8
6.5
9.57
8.98
%
6.70
927
5831
954
6219
2.46
60.13
11.7
6.5
0.71
0.68
%
0.78
925
5810
750
4398
2.41
60.07
4.9
2.6
—
—
—
0
0
954
6222
2.46
60.01
11.6
6.4
2.82
2.87
%
0.24
925
5817
953
6223
2.45
59.62
11.1
6.3
58.99
57.68
%
2.56
932
5943
424
1946
2.64
57.33
2.0
1.8
—
—
—
0
0
958
6354
2.40
56.56
11.5
6.4
24.57
27.14
%
10.16
935
6016
903
5870
2.35
55.37
5.0
3.0
357.74
137.73
ug/l
6.72
868
5449
989
6741
2.37
53.45
11.4
6.2
0.04
0.04
e9/l
0.59
886
5747
197
614
3.54
52.64
3.1
1.9
3.67
1.87
ug/l
1.06
180
548
985
6727
2.35
52.61
11.4
6.2
0.62
0.60
e9/l
1.97
880
5736
996
6847
2.35
52.18
11.5
6.3
1.61
1.93
e9/l
10.27
905
5989
332
1421
2.72
50.96
24.4
9.7
111.30
121.22
g/l
12.61
325
1395
258
967
3.01
50.75
6.0
3.8
7.41
7.41
ph
0.22
221
814
38
18
21.63
50.73
3.7
1.2
128.00
5.22
ug/l
0.68
38
18
1003
6962
2.33
50.65
12.0
6.5
0.18
0.20
e9/l
1.61
902
6051
260
990
2.97
49.66
6.1
3.7
4.86
5.17
kpa
7.07
246
957
45
32
14.47
49.48
1.1
1.1
—
—
—
0
0
593
3367
2.26
48.44
5.0
2.5
—
—
—
0
0
1144
8528
2.43
47.01
13.7
3.1
164.96
48.30
u/l
39.08
1108
8002
239
895
2.99
46.88
24.0
11.0
22.99
24.31
mmol/l
5.19
233
876
228
833
3.05
46.71
28.1
12.1
14.56
15.96
%
9.43
219
808
461
2387
2.34
46.56
2.1
1.7
1224.75
1186.44
nmol/l
0.35
366
1805
285
1185
2.73
45.91
2.4
3.0
63.84
66.60
g/l
4.57
258
1091
674
4105
2.16
45.46
7.6
4.4
7.41
7.40
ph
5.36
543
2979
293
1245
2.68
45.17
6.7
3.0
4.99
4.57
kpa
2.04
277
1209
1043
7559
2.24
44.49
16.7
9.6
4.14
4.18
e9/l
0.16
958
6567
1078
7976
2.25
42.80
16.8
5.4
7.31
6.73
mmol/l
8.85
1049
7634
111
275
4.28
40.86
1.5
1.3
49.12
61.18
mmol/l
2.32
74
222
489
2716
2.19
40.76
3.7
2.9
492.96
537.71
mosm/kgh2o
4.90
446
2386
892
6224
2.07
40.03
5.4
2.9
—
—
estimate
—
0
0
286
1270
2.55
39.91
2.2
2.2
364.26
378.69
nmol/l
0.58
268
1177
333
1589
2.41
39.73
2.2
1.8
—
—
—
0
0
641
4005
2.05
38.66
4.1
3.3
—
—
—
0
0
72
131
5.72
38.09
1.3
1.2
—
—
—
0
0
107
277
4.08
37.11
3.4
3.4
1001.81
1450.34
u/ml
0.15
93
259
497
2890
2.08
35.91
3.1
1.8
2.80
1.27
mg/l
9.07
434
2256
147
490
3.22
34.87
1.5
1.2
—
—
—
0
0
182
689
2.87
34.53
7.0
3.8
—
—
—
0
0
229
992
2.54
33.27
25.5
10.9
1.41
1.30
%
1.09
229
985
1238
10093
2.29
32.93
28.8
8.1
130.39
78.68
u/l
51.45
1220
9594
472
2784
2.01
32.13
1.4
1.3
3.24
1.64
u/ml
0.64
101
761
236
1053
2.47
32.13
5.4
4.0
97.31
92.14
ng/l
0.33
211
924
654
4314
1.91
32.00
2.9
2.3
345.55
225.26
u/l
1.61
631
4091
679
4544
1.90
31.69
4.8
3.4
132.50
94.89
e6/l
0.24
562
3538
151
543
2.98
31.37
7.4
3.9
24.22
24.93
mmol/l
1.60
143
507
341
1811
2.14
30.63
1.4
1.2
—
—
—
0
0
579
3715
1.91
30.43
4.4
3.2
—
0.00
estimate
—
0
18
214
935
2.50
30.39
7.5
3.0
115.59
129.06
g/l
10.34
202
910
654
4367
1.88
30.35
4.9
3.3
2983.13
1384.52
ng/l
3.53
575
3766
601
3910
1.90
30.21
4.5
3.3
1.02
0.42
e6/l
2.91
489
2933
395
2258
2.02
28.89
3.9
3.2
3.19
2.08
e6/l
1.29
231
1151
509
3188
1.90
28.37
3.5
2.7
6.90
5.29
e6/l
1.44
473
2924
162
656
2.65
26.80
5.8
3.0
24.00
25.17
mmol/l
3.59
149
629
412
2450
1.94
26.56
3.6
3.0
1.36
1.02
e6/l
0.99
245
1348
716
5077
1.78
26.05
5.8
4.0
92.03
113.69
e6/l
0.40
571
3679
238
1179
2.21
25.08
5.5
4.2
0.74
0.66
%
0.26
152
356
118
420
2.96
24.87
1.6
1.5
231.91
281.35
ug/g
1.44
62
259
547
3621
1.80
24.80
4.7
2.8
380.64
349.51
umol/l
6.48
492
3182
114
400
3.00
24.64
17.7
7.5
1.86
1.33
mmol/l
1.95
98
356
236
1173
2.20
24.64
1.7
1.4
—
—
—
0
0
155
642
2.58
24.43
15.7
5.7
1.90
1.57
%
3.24
141
612
796
5891
1.75
24.35
3.8
2.4
72.27
77.72
nmol/l
5.42
735
5296
78
218
3.72
24.25
3.8
4.3
2.52
1.48
%
0.70
72
199
244
1242
2.15
23.95
5.9
4.3
0.77
0.93
%
0.68
153
386
291
4826
0.51
23.55
3.5
3.3
—
—
—
0
0
1058
8536
1.81
23.54
6.9
4.8
5076.79
1793.61
e6/l
0.40
14
135
223
1104
2.20
23.45
3.7
3.1
310.70
216.96
ng/l
1.47
208
1014
128
492
2.75
23.39
3.5
3.5
394.54
271.85
mg/l
0.85
79
211
205
984
2.25
23.24
2.1
2.8
—
—
—
0
0
143
587
2.59
22.93
16.6
6.0
0.87
0.87
%
0.03
131
558
29
34
8.68
22.81
2.1
1.2
—
—
—
0
0
107
386
2.91
21.99
7.2
3.1
61.61
62.09
%
0.07
100
378
73
209
3.62
21.91
1.7
1.4
25.52
32.83
g/l
4.69
65
190
95
321
3.09
21.91
1.4
1.7
—
—
—
0
0
63
165
3.94
21.48
1.4
1.5
272.31
277.30
mosm/kgh2o
0.77
48
120
62
163
3.92
21.03
1.8
1.4
—
—
—
0
0
93
321
3.02
20.67
3.7
4.2
—
—
—
0
0
38
68
5.71
20.45
3.7
4.1
282.28
69.45
mg/l
0.47
29
51
185
901
2.20
20.13
16.7
7.5
23.17
24.62
mmol/l
4.25
177
868
237
1280
2.01
19.61
8.1
4.3
7.38
7.36
ph
1.44
209
921
124
512
2.55
19.60
3.3
2.9
23.17
24.79
mmol/l
3.27
119
505
795
6097
1.65
19.52
2.8
2.2
92.94
95.01
pmol/l
0.55
453
3272
571
4031
1.67
19.38
2.2
1.7
18.73
20.12
nmol/l
1.62
518
3414
223
1185
2.04
19.28
6.1
4.4
0.05
0.11
%
1.68
131
330
58
158
3.78
18.73
4.6
1.9
—
—
—
0
0
56
149
3.87
18.69
4.6
4.6
—
—
—
0
0
282
1654
1.87
18.16
2.2
1.4
—
—
—
0
0
410
2696
1.72
17.89
6.0
4.1
229.07
449.55
ng/l
1.74
355
2169
43
97
4.53
17.83
4.2
2.2
38.71
5.19
umol/l
3.36
38
67
97
374
2.70
17.59
5.1
3.6
2.56
2.00
index
0.48
57
201
62
185
3.45
17.51
1.8
1.3
1402.07
1777.02
e6/l
0.33
43
127
80
280
2.96
17.36
23.2
9.0
105.19
105.45
mmol/l
0.14
72
258
80
280
2.96
17.36
23.2
9.0
12.03
11.13
mmol/l
1.05
72
258
65
201
3.33
17.36
2.7
2.2
1.15
0.89
%
1.27
57
139
46
113
4.17
17.12
1.4
1.3
0.51
0.35
g/l
1.36
32
84
46
113
4.17
17.12
1.4
1.3
8.10
6.51
g/l
1.46
32
84
46
113
4.17
17.12
1.4
1.3
3.01
2.73
g/l
0.40
32
83
118
508
2.44
17.05
2.2
3.8
73.60
61.05
mg/l
0.37
99
437
118
510
2.43
16.91
2.2
3.8
57.43
72.10
mg/l
0.26
98
440
123
543
2.38
16.81
1.5
1.8
3.12
8.02
iu/ml
2.63
18
123
42
98
4.38
16.70
1.1
1.1
—
—
—
0
0
40
90
4.54
16.64
1.2
1.1
—
—
—
0
0
28
46
6.18
16.42
1.0
1.0
—
—
—
0
0
77
273
2.92
16.34
3.9
1.6
—
—
—
0
0
59
182
3.33
15.83
2.4
2.3
33.05
32.63
pg
0.27
59
182
77
279
2.85
15.71
6.1
5.0
2.94
2.66
mmol/l
0.31
51
186
213
1192
1.92
15.71
6.1
4.6
0.01
0.13
%
2.33
115
302
49
137
3.66
15.27
1.2
1.1
—
—
—
0
0
634
4802
1.55
14.99
4.4
3.4
6.93
7.76
mmol/l
5.35
568
4050
105
457
2.40
14.81
2.2
3.7
4.82
4.43
ratio
0.04
61
268
67
233
2.96
14.73
1.5
1.7
—
—
—
0
0
43
114
3.85
14.46
1.4
1.3
—
—
—
0
0
53
162
3.35
14.45
1.7
1.3
28067.27
112134.38
e6/l
1.09
30
92
49
145
3.46
14.05
4.2
4.2
62.20
55.63
%
1.21
44
128
683
5311
1.52
14.02
5.8
4.1
71.17
81.84
ng/l
0.16
581
3936
37
90
4.19
13.98
1.3
1.2
33.31
35.10
mmol/l
0.17
32
81
408
2849
1.59
13.46
1.9
1.7
565.99
28017305.20
pmol/l
2.35
349
2370
118
571
2.16
12.95
1.8
2.7
6.89
7.31
g/l
1.36
107
523
118
571
2.16
12.95
1.8
2.7
4.22
3.69
g/l
0.96
108
523
118
571
2.16
12.95
1.8
2.7
4.05
4.17
g/l
0.59
107
523
80
328
2.52
12.85
4.3
1.7
—
—
—
0
0
72
281
2.64
12.79
1.3
1.8
0.90
0.85
nmol/l
0.22
61
236
1156
12671
0.62
12.74
6.7
6.0
2.43
2.66
mmol/l
16.24
1072
11751
111
533
2.17
12.43
1.9
2.7
2.78
2.96
g/l
1.20
101
485
49
158
3.17
12.29
1.7
1.5
—
—
—
0
0
1136
12476
0.63
12.13
6.3
5.3
4.22
4.56
mmol/l
21.35
1059
11633
76
316
2.48
11.87
3.3
3.5
0.86
0.84
nmol/l
0.18
63
257
66
257
2.64
11.79
4.8
2.2
—
—
—
0
0
1130
12405
0.64
11.68
6.2
5.2
1.32
1.44
mmol/l
16.00
1046
11474
48
158
3.11
11.65
1.8
1.3
—
—
—
0
0
205
3203
0.58
11.52
2.8
3.3
0.71
0.76
ug/l
0.30
140
2091
80
355
2.32
10.84
4.4
1.7
—
—
—
0
0
30
76
4.01
10.78
1.5
1.4
1.29
1.12
nmol/l
0.44
21
55
202
1243
1.72
10.74
2.6
2.5
12.09
7.42
ug/l
0.93
172
1112
14
5
28.24
10.73
1.1
1.0
—
—
—
0
0
80
357
2.31
10.70
4.4
1.7
—
—
—
0
0
80
357
2.31
10.70
4.4
1.7
—
—
—
0
0
44
145
3.10
10.67
1.0
1.1
—
—
—
0
0
595
4679
1.45
10.62
4.6
4.2
20.78
7.94
mg/mmol
2.34
420
2953
76
336
2.33
10.39
2.3
2.3
117.47
131.23
g/l
4.19
60
269
30
79
3.85
10.24
1.2
1.2
7.44
7.39
ph
1.01
20
60
83
387
2.21
10.02
1.3
1.2
32.40
22.98
u/ml
—
6
17
37
115
3.27
9.89
1.5
1.2
14.41
11.73
u/l
0.23
32
103
45
158
2.91
9.80
1.2
1.7
20.06
34.19
ng/l
1.15
45
158
51
193
2.70
9.68
1.4
1.5
—
—
—
0
0
51
193
2.70
9.68
1.4
1.5
—
—
—
0
0
51
193
2.70
9.68
1.4
1.5
—
—
—
0
0
51
193
2.70
9.68
1.4
1.5
—
—
—
0
0
1282
13598
0.61
9.67
66.9
25.5
4.07
4.49
e12/l
88.36
1255
13308
1282
13597
0.61
9.65
66.7
25.4
30.78
30.41
pg
7.39
1269
13456
80
374
2.20
9.61
1.2
1.2
3.19
8.29
u/ml
0.73
15
49
1283
13601
0.61
9.53
67.6
25.7
122.85
135.46
g/l
106.19
1268
13459
1283
13598
0.61
9.45
71.1
26.1
36.92
40.40
%
87.07
1266
13452
71
318
2.29
9.45
1.1
1.1
—
—
—
0
0
39
129
3.08
9.43
6.7
3.6
14.97
11.46
index
0.56
33
82
164
987
1.74
9.41
1.2
1.2
—
—
—
0
0
1283
13595
0.61
9.36
66.7
25.5
92.58
91.33
fl
12.32
1269
13456
1283
13594
0.61
9.34
66.9
25.6
210.86
246.54
e9/l
42.16
1258
13344
1284
13600
0.61
9.28
66.9
25.6
7.01
6.78
e9/l
2.21
1260
13309
79
373
2.18
9.27
1.2
1.2
1.87
2.64
u/ml
—
10
27
76
354
2.21
9.22
4.0
1.7
—
—
—
0
0
576
4594
1.41
9.13
4.0
3.5
95.12
45.78
mg/l
2.87
418
2988
97
501
2.00
8.99
1.8
2.8
11.95
10.60
g/l
1.06
85
450
589
4727
1.40
8.96
4.9
3.5
2.30
2.35
mmol/l
13.92
542
4292
23
55
4.23
8.93
1.4
1.3
71.88
56.61
%
1.12
16
44
245
1662
1.57
8.77
4.1
3.4
5.66
4.91
e9/l
0.33
209
1432
42
152
2.81
8.69
1.4
1.1
—
—
—
0
0
19
40
4.80
8.60
1.4
1.4
—
—
—
0
0
172
1076
1.68
8.56
6.1
3.9
1.20
1.22
mmol/l
4.84
163
928
54
224
2.46
8.54
4.2
3.2
3.38
4.36
e9/l
2.76
54
224
43
1022
0.40
8.38
1.1
1.4
—
—
—
0
0
76
369
2.12
8.33
2.4
2.3
12.34
12.05
mg/l
0.10
70
339
44
169
2.65
8.15
1.4
1.3
—
—
—
0
0
38
135
2.86
8.15
1.1
1.2
—
—
—
0
0
59
1222
0.46
8.08
1.6
2.1
3.87
3.53
ratio
0.75
45
985
505
4005
1.39
8.03
11.6
6.3
—
—
—
0
0
114
655
1.80
7.67
1.3
1.2
—
—
—
0
0
1097
11899
0.71
7.53
5.5
4.4
1.35
1.30
mmol/l
1.17
1014
10909
697
5862
1.35
7.53
23.9
11.6
0.01
0.00
e9/l
0.71
587
4785
67
324
2.12
7.45
1.3
1.3
264.20
205.93
miu/ml
0.33
13
147
25
73
3.47
7.41
4.8
3.1
2780.32
1307.04
u/ml
0.98
25
73
20
52
3.88
6.99
1.7
1.6
3072.00
1828.57
titre
—
5
7
39
886
0.43
6.82
1.4
1.8
3.19
3.48
mmol/l
0.77
25
651
40
163
2.49
6.63
1.3
1.2
—
—
—
0
0
52
241
2.20
6.46
2.8
2.2
254.71
7856.23
u/l
2.56
21
96
30
107
2.84
6.44
1.7
2.2
1046.70
1236.26
e6/l
0.53
23
97
58
282
2.10
6.40
4.2
3.1
56.17
58.54
%
0.86
58
282
16
27
5.98
6.30
1.6
1.3
22.18
24.33
%
0.09
11
21
34
133
2.59
6.14
1.2
1.3
1.15
1.39
nmol/l
0.58
34
116
18
48
3.78
6.09
1.4
1.7
—
—
—
0
0
14
21
6.72
6.04
1.0
1.4
—
—
mmol/l
—
0
0
173
1180
1.53
5.99
3.4
2.5
1.10
0.49
e6/l
0.73
168
1125
450
3638
1.34
5.98
1.7
1.4
—
—
—
0
0
27
96
2.85
5.85
1.2
1.4
9.73
9.03
mmol/l
0.34
27
91
210
1498
1.47
5.84
1.5
1.4
—
—
—
0
0
10
9
11.18
5.79
1.4
1.0
—
—
—
0
0
38
162
2.38
5.76
2.0
2.6
1.71
1.38
g/24h
0.22
29
94
656
5612
1.30
5.75
4.9
3.5
6.34
6.22
ph
1.96
351
3166
74
409
1.85
5.70
6.3
4.3
3.90
3.94
mmol/l
0.19
74
404
1149
12241
0.74
5.54
6.4
5.3
6.40
6.00
mmol/l
11.36
1064
11200
15
28
5.40
5.54
1.7
1.9
—
—
—
0
0
22
72
3.09
5.50
4.0
2.9
—
—
—
0
0
16
35
4.61
5.18
14.3
7.6
5.91
5.18
kpa
0.50
16
35
442
5283
0.77
5.03
4.5
5.6
2.39
2.80
ug/l
0.41
400
4772
36
160
2.28
5.00
8.2
5.3
7.24
7.24
mmol/l
0.00
31
133
12
405
0.29
4.93
1.0
1.2
1.44
1.52
g/l
0.30
12
405
12
20
6.04
4.91
2.8
1.3
—
—
—
0
0
33
143
2.34
4.87
1.6
2.4
—
—
—
0
0
1280
13363
0.71
4.81
56.8
22.1
93.78
80.18
umol/l
11.53
1264
13219
207
1532
1.41
4.71
2.8
2.4
210.56
136.89
ug/g
1.43
179
1222
18
58
3.13
4.64
1.4
1.2
—
—
—
0
0
40
192
2.11
4.64
1.9
2.7
—
—
—
0
0
14
31
4.55
4.56
1.7
1.1
—
—
—
0
0
8
8
10.05
4.52
2.8
2.5
—
—
—
0
0
13
28
4.67
4.37
2.2
1.8
0.04
0.28
e9/l
—
6
12
29
125
2.35
4.35
1.1
1.2
—
—
—
0
0
40
198
2.05
4.30
1.1
1.1
20.34
106.67
iu/ml
—
5
40
31
139
2.26
4.26
2.4
2.2
—
—
—
0
0
49
262
1.90
4.25
1.6
1.3
73.70
38.30
u/l
0.62
41
220
23
528
0.43
4.21
1.8
1.7
—
—
—
0
0
21
80
2.65
4.07
1.8
2.3
448.93
604.03
e6/l
0.49
14
68
23
93
2.50
3.97
2.3
2.9
36.60
39.87
%
—
10
44
14
43
3.28
3.91
1.6
1.3
8.56
96.00
ug/l
—
8
16
39
199
1.99
3.89
1.3
1.2
3.96
5.76
u/ml
0.49
27
88
21
82
2.58
3.89
1.9
2.6
218.40
226.73
e6/l
0.05
15
74
10
19
5.29
3.83
2.0
1.5
—
—
—
0
0
779
7016
1.23
3.82
5.6
4.0
22.36
3.50
estimate
0.83
183
1503
21
83
2.55
3.80
1.0
1.2
148.63
143.14
nmol/l
0.16
21
83
1272
13228
0.75
3.79
35.4
12.2
57.34
26.17
u/l
10.46
1257
12866
109
748
1.49
3.72
2.9
3.7
4.17
4.51
pmol/l
1.94
91
669
53
304
1.77
3.72
1.4
1.4
2.87
40.10
e6/l
1.11
39
226
10
20
5.03
3.69
10.6
11.4
9.13
5.30
mmol/l
—
10
20
227
1774
1.33
3.66
1.3
1.3
—
—
—
0
0
15
51
2.96
3.58
2.1
1.6
36.41
39.76
g/l
0.96
15
51
13
352
0.36
3.54
1.2
1.2
—
—
—
0
0
6
6
10.03
3.50
3.7
2.7
4.52
4.27
mmol/l
—
6
6
17
63
2.72
3.49
1.2
1.0
1692.76
1666.57
miu/ml
0.03
17
63
49
281
1.77
3.46
1.5
1.4
—
—
—
0
0
24
106
2.28
3.46
1.5
2.1
38.88
38.34
%
0.06
24
106
210
1640
1.33
3.41
5.2
5.0
33.43
32.38
%
0.60
165
1075
33
167
2.00
3.40
1.4
1.2
—
—
—
0
0
7
10
7.03
3.36
1.0
1.0
—
—
—
0
0
52
308
1.71
3.30
1.5
1.5
531.39
543.44
e6/l
0.01
41
239
1145
12022
0.80
3.27
9.2
6.6
40.50
39.60
mmol/mol
2.07
1087
11218
1236
12862
0.78
3.26
39.5
15.2
—
—
—
0
0
762
6941
1.20
3.05
5.6
3.9
0.00
0.00
estimate
0.50
177
1474
424
3653
1.22
3.04
3.8
3.0
0.25
0.02
—
8
82
23
106
2.19
3.03
2.0
2.3
781.23
645.70
ml
0.50
13
67
772
7063
1.19
2.88
5.6
4.0
0.00
0.23
estimate
0.54
168
1402
7
13
5.40
2.87
1.3
1.4
—
—
—
0
0
485
5477
0.83
2.84
2.5
1.9
1.49
1.35
mmol/l
1.16
437
4591
19
84
2.28
2.77
1.2
1.5
—
—
—
0
0
973
10329
0.84
2.77
57.5
21.9
331.89
332.41
g/l
0.85
968
10278
572
5123
1.19
2.66
2.4
2.2
—
—
—
0
0
67
449
1.52
2.64
1.6
1.6
23.99
13.90
u/ml
—
8
102
52
329
1.60
2.63
2.2
2.4
205.42
97.70
ug/min
0.68
28
193
23
113
2.05
2.62
2.9
3.2
76.19
25.80
mg/l
0.54
17
84
8
20
4.02
2.57
1.0
1.4
50.50
66.90
ug/l
—
8
20
7
16
4.39
2.47
2.3
3.4
—
—
—
0
0
84
601
1.42
2.40
1.1
1.2
—
—
—
0
0
29
160
1.83
2.40
3.7
2.6
4.15
4.06
mmol/l
0.35
29
160
29
160
1.83
2.40
3.7
2.6
106.41
105.62
mmol/l
0.38
29
160
5
8
6.27
2.37
1.2
1.3
—
—
—
0
0
23
118
1.96
2.36
1.4
1.2
—
—
—
0
0
10
33
3.04
2.36
1.2
1.6
—
—
—
0
0
38
610
0.61
2.35
1.1
1.1
—
—
—
0
0
18
84
2.16
2.35
2.0
2.2
524.17
503.57
min
0.41
12
56
25
133
1.89
2.32
1.1
1.3
339324.31
118344.70
e6/l
0.31
13
90
8
23
3.49
2.27
1.0
1.0
—
—
—
0
0
25
137
1.84
2.14
1.6
1.5
0.15
0.33
nmol/l
2.73
19
102
89
661
1.37
2.08
2.6
2.2
0.00
1.34
estimate
0.51
17
189
14
62
2.27
2.08
1.2
1.1
1.10
1.07
ratio
0.30
14
53
323
2807
1.19
2.06
3.5
3.0
2.47
2.45
mmol/l
2.30
282
2533
439
3916
1.17
2.05
5.9
4.1
0.00
0.01
estimate
1.15
148
1355
51
344
1.50
2.01
1.5
1.2
—
—
—
0
0
27
156
1.74
1.97
3.9
2.6
1.19
1.20
mmol/l
0.36
27
156
5
11
4.56
1.94
1.0
1.0
—
—
—
0
0
19
99
1.93
1.90
1.9
1.5
491.67
295.40
mu/l
0.63
12
81
51
349
1.48
1.89
1.4
1.7
22239.72
15141.44
e6/l
0.37
39
252
23
394
0.58
1.89
23.9
10.2
—
—
—
0
0
27
159
1.71
1.86
1.4
1.4
—
—
—
0
0
19
101
1.89
1.81
2.8
1.1
78.05
108.86
pmol/l
1.88
19
101
49
338
1.46
1.77
1.5
1.4
9.24
9.02
u/l
0.04
37
274
14
68
2.07
1.70
1.6
1.9
—
—
—
0
0
47
325
1.46
1.68
6.2
4.7
—
—
—
0
0
88
678
1.32
1.67
2.5
2.4
—
—
—
0
0
10
40
2.51
1.66
1.3
1.2
30.60
28.18
s
—
10
40
7
25
2.81
1.65
1.0
2.0
16.94
17.60
umol/l
—
7
25
27
167
1.63
1.59
2.6
1.7
—
—
—
0
0
31
199
1.57
1.57
2.3
2.6
—
—
—
0
0
8
33
2.43
1.54
1.8
1.2
—
—
—
0
0
20
115
1.75
1.53
1.6
2.1
2.75
1.43
u/field
0.50
12
67
1127
11641
0.87
1.50
5.9
5.3
2.06
1.93
mu/l
2.19
1054
10715
129
1068
1.23
1.40
5.3
4.0
—
—
—
0
0
17
96
1.78
1.39
1.4
2.5
8.48
7.84
mmol/l
0.19
17
96
23
142
1.63
1.38
3.6
2.6
—
—
—
0
0
9
41
2.20
1.37
1.3
1.9
36.22
31.63
%
—
9
41
26
394
0.65
1.35
1.2
1.1
—
—
—
0
0
16
90
1.79
1.33
3.7
2.8
14.89
16.18
%
0.65
16
90
82
1024
0.79
1.29
1.4
1.4
—
—
—
0
0
5
18
2.78
1.28
1.0
1.2
0.01
0.12
u/ml
—
5
18
6
26
2.31
1.18
1.3
1.8
—
—
—
0
0
21
133
1.59
1.17
1.9
2.1
—
—
—
0
0
15
87
1.73
1.15
2.7
1.9
115.43
109.70
ng/l
0.07
15
87
23
151
1.53
1.12
1.0
1.1
2.08
2.40
eliau/ml
—
6
64
7
32
2.19
1.08
1.6
1.5
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
9
48
1.88
1.00
2.9
2.2
—
—
—
0
0
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
23
159
1.45
0.91
1.3
1.6
82.92
62.30
%
3.06
12
101
399
3717
1.10
0.89
4.9
3.5
0.00
0.05
estimate
1.23
142
1166
10
57
1.76
0.83
1.1
1.3
6.15
6.29
mmol/l
—
10
57
14
89
1.58
0.81
2.2
1.4
99.79
82.60
umol/l
0.84
14
89
332
3084
1.10
0.79
6.5
4.1
1.02
1.02
kg/l
0.24
253
2074
32
418
0.76
0.79
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
38.51
—
0
24
149
1323
1.14
0.79
1.6
1.5
—
—
—
0
0
145
1288
1.14
0.77
2.3
2.2
0.00
0.02
estimate
0.78
22
250
1012
10382
0.92
0.76
56.2
20.8
15.13
13.67
%
87.21
1005
10246
71
597
1.20
0.75
2.3
2.8
—
—
—
0
0
1276
12950
0.90
0.72
58.1
20.4
3.99
3.99
mmol/l
0.02
1258
12694
116
1022
1.15
0.70
3.6
2.7
5.96
6.09
ph
1.00
92
687
15
102
1.48
0.67
1.1
1.3
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
19
137
1.39
0.64
1.4
1.2
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
1277
12929
0.92
0.56
57.9
20.2
138.20
139.68
mmol/l
50.64
1260
12690
8
55
1.46
0.56
2.5
3.0
—
—
—
0
0
204
2194
0.92
0.52
1.3
1.3
10.29
11.56
u/ml
0.09
63
840
75
659
1.15
0.51
4.9
3.7
1.02
1.02
ratio
0.39
69
612
1268
12523
1.08
0.50
46.9
16.9
26.12
25.87
mg/l
0.11
1213
10391
955
9738
0.95
0.46
4.8
4.3
14.90
14.88
pmol/l
0.08
881
8893
7
49
1.43
0.46
2.7
3.2
—
—
—
0
0
20
156
1.29
0.45
1.3
1.5
—
—
—
0
0
5
32
1.56
0.42
1.8
1.3
8.46
8.00
mmol/l
—
5
32
23
283
0.81
0.41
1.4
1.3
—
—
—
0
0
119
1293
0.91
0.41
2.3
2.3
13.50
13.36
nmol/l
0.06
110
1161
8
61
1.31
0.39
1.1
1.1
470.46
205.22
iu/ml
—
8
61
92
845
1.09
0.34
1.4
1.3
229.12
234.44
u/ml
0.02
86
781
39
340
1.15
0.33
2.2
1.9
1.71
21.57
iu/l
0.60
12
135
11
144
0.76
0.33
5.3
2.8
13.55
13.24
%
0.65
11
144
18
146
1.24
0.32
1.4
1.3
—
—
nmol/l
—
0
0
11
83
1.33
0.32
1.1
1.0
—
—
—
0
0
15
119
1.26
0.31
1.2
1.1
—
—
—
0
0
87
804
1.09
0.29
1.1
1.2
102.21
140.35
u/ml
0.64
28
312
10
130
0.77
0.29
2.4
2.7
—
—
—
0
0
7
57
1.23
0.29
1.0
1.3
145.71
180.91
mmol/24h
—
7
57
69
632
1.10
0.28
2.3
1.9
—
—
—
0
0
8
63
1.27
0.27
1.3
1.1
—
—
—
0
0
537
5253
1.03
0.25
5.9
3.9
0.00
0.03
estimate
4.00
150
1228
5
38
1.32
0.23
2.4
2.2
—
—
—
0
0
13
106
1.23
0.23
1.0
1.0
524.00
293.53
ng/l
—
8
66
13
107
1.22
0.21
1.0
1.0
782.57
630.11
ng/l
—
7
66
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
8
104
0.77
0.21
5.9
2.5
25.25
34.46
mg/l
—
8
76
0
14
0.00
0.20
0.0
1.0
—
0.25
—
0
6
23
203
1.14
0.19
1.0
1.1
—
—
—
0
0
23
203
1.14
0.19
1.1
1.1
—
—
—
0
0
91
864
1.06
0.17
1.1
1.3
—
—
—
0
0
89
853
1.05
0.13
1.7
1.6
—
—
—
0
0
18
161
1.12
0.13
1.2
1.1
0.73
2.39
u/ml
1.67
13
79
42
445
0.94
0.11
1.6
1.4
26.99
27.14
iu/l
0.01
34
382
7
67
1.04
0.08
1.3
1.6
—
—
—
0
0
13
118
1.10
0.07
1.3
1.4
8.14
29.59
%
—
7
72
23
217
1.06
0.06
1.1
1.1
0.22
1.69
u/ml
2.32
12
121
19
178
1.07
0.05
1.2
1.1
0.30
1.52
u/ml
1.73
14
92
19
179
1.06
0.05
1.6
1.2
—
—
—
0
0
18
170
1.06
0.04
1.4
1.3
0.67
11.14
nmol/l
0.50
18
162
14
132
1.06
0.02
2.9
1.9
—
—
—
0
0
235
2344
1.00
0.00
1.3
1.3
60.42
30.97
iu/ml
1.66
79
722
18
184
0.98
0.00
1.1
1.0
5.42
4.40
u/ml
—
9
94
18
183
0.98
0.00
1.4
1.2
—
—
—
0
0
14
135
1.04
0.00
1.2
1.0
0.02
0.36
u/ml
—
8
50
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
30.86
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.2
—
—
—
0
0
18
180
1.00
-0.00
1.1
1.0
1.74
2.30
u/ml
—
8
79
5
58
0.86
-0.00
1.2
1.2
8.20
8.83
mm/h
—
5
58
0
8
0.00
-0.00
0.0
1.4
—
0.16
—
0
8
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
59
1.02
-0.00
1.3
1.1
—
294.21
—
0
14
0
6
0.00
-0.00
0.0
1.0
—
1484.17
—
0
6
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_HEPFAIL and mortality.

Females

Parameter HR [95% CI] p-value
K11_HEPFAIL 5.676 [4.64, 6.95] < 0.001
Birth year 0.999 [0.99, 1.01] 0.734

During the follow-up period (1.1.1998 — 31.12.2019), 1261 out of 2843 females with K11_HEPFAIL died.

Males

Parameter HR [95% CI] p-value
K11_HEPFAIL 8.309 [6.57, 10.51] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 1973 out of 3664 males with K11_HEPFAIL died.

Mortality risk

Mortality risk for people of age

years, who have K11_HEPFAIL.

N-year risk Females Males
1 0.605% 0.979%
5 3.398% 8.39%
10 9.095% 20.469%
15 16.851% 36.282%
20 27.438% 53.177%

Relationships between endpoints

Index endpoint: K11_HEPFAIL – Hepatic failure, not elsewhere classified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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