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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Flatback syndrome

M13_FLATBACK

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M40.3
  • Cause of death: ICD-10 M40.3

2 out of 7 registries used, show all original rules.

39

4. Check minimum number of events

None

39

5. Include endpoints

None

39

6. Filter based on genotype QC (FinnGen only)

34

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M40
Name in latin
Syndroma dorsi plani

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 184 99 85
Only index persons 176 96 80
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 66.47 60.97
Only index persons 63.97 66.31 61.17

-FinnGen-

Key figures

All Female Male
Number of individuals 34 24 10
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 69.66 71.38 65.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
15
21
11.60
7.77
4.7
5.1
—
—
—
0
0
30
148
8.15
6.24
3.4
2.6
—
—
estimate
—
0
0
22
99
4.29
4.22
5.6
2.6
51.73
57.88
u/l
0.61
22
90
13
41
4.43
3.57
1.5
1.7
—
—
—
0
0
7
10
8.41
3.55
1.3
1.2
—
—
—
0
0
23
123
3.54
3.13
2.3
1.8
1.36
1.31
mmol/l
0.11
23
98
10
28
4.57
3.09
1.4
1.1
—
—
—
0
0
10
29
4.40
2.99
1.5
1.5
—
—
—
0
0
11
35
4.10
2.99
1.7
1.2
—
—
—
0
0
20
111
2.87
2.35
4.3
2.6
—
—
—
0
0
18
97
2.76
2.20
1.9
1.6
24.44
21.37
nmol/l
0.42
18
81
18
99
2.68
2.09
2.1
5.8
—
—
—
0
0
18
100
2.65
2.04
7.7
5.4
—
—
—
0
0
23
148
2.62
1.88
2.5
2.1
122.54
97.96
pmol/l
0.88
15
65
5
13
4.29
1.78
2.6
2.2
—
0.20
estimate
—
0
5
19
115
2.43
1.73
3.1
3.4
13.90
37.52
mg/l
—
10
75
6
20
3.40
1.66
1.7
1.6
—
—
—
0
0
16
91
2.40
1.65
5.1
3.7
—
—
—
0
0
19
117
2.36
1.64
3.3
4.1
2.02
8.50
mg/mmol
—
10
68
15
83
2.41
1.64
3.5
2.4
1.69
2.72
mg/l
2.01
15
70
7
27
2.98
1.61
1.9
1.7
0.20
0.22
g/l
—
7
27
7
29
2.76
1.48
1.1
1.4
—
—
—
0
0
35
312
+∞
1.45
32.9
14.7
—
—
—
0
0
35
311
+∞
1.44
6.9
5.6
5.95
5.99
mmol/l
0.08
35
278
21
141
2.22
1.42
5.8
3.8
6.30
6.10
ph
0.35
15
72
8
35
2.66
1.38
2.3
3.0
60.25
77.30
ng/l
—
8
29
23
163
2.20
1.32
10.0
4.0
33.16
35.47
g/l
1.31
23
153
6
116
0.42
1.24
1.8
3.8
—
—
—
0
0
0
35
0.00
1.23
0.0
1.4
—
—
—
0
0
20
137
2.07
1.23
3.6
3.2
88.15
119.11
ug/l
0.77
20
127
12
70
2.09
1.10
1.4
1.3
22.39
35.11
iu/ml
—
7
26
30
252
2.33
0.97
40.2
20.8
334.43
330.37
g/l
1.45
30
252
6
31
2.12
0.89
1.0
1.7
—
—
—
0
0
17
120
1.81
0.87
2.6
3.2
2.31
2.35
mmol/l
0.80
17
109
0
25
0.00
0.83
0.0
2.9
—
—
—
0
0
21
160
1.78
0.82
9.7
5.7
0.67
0.56
e9/l
1.32
21
134
9
55
1.85
0.82
2.6
2.5
2.69
2.34
g/l
—
9
50
21
161
1.76
0.80
9.8
6.0
2.02
2.20
e9/l
0.17
21
141
19
146
1.66
0.68
11.9
6.6
8.95
8.62
%
0.23
19
137
8
52
1.70
0.65
2.8
2.6
17.67
20.79
%
—
8
47
8
54
1.62
0.63
1.9
4.5
1.14
1.10
mmol/l
—
8
48
20
158
1.62
0.62
10.1
5.8
0.07
0.04
e9/l
2.11
20
132
0
19
0.00
0.62
0.0
1.7
—
—
—
0
0
9
59
1.70
0.62
2.6
2.5
13.00
11.64
umol/l
—
9
54
19
149
1.60
0.60
12.2
6.6
28.11
27.02
%
0.18
19
142
22
181
1.58
0.55
8.0
6.5
8.72
10.16
umol/l
0.91
22
165
5
30
1.77
0.46
2.6
2.0
—
0.50
estimate
—
0
6
18
146
1.48
0.45
12.6
6.5
2.59
2.72
%
0.12
18
137
18
146
1.48
0.45
12.5
6.5
0.94
0.67
%
1.36
18
136
20
166
1.48
0.45
10.6
6.0
0.21
0.19
e9/l
0.30
20
143
5
32
1.65
0.44
2.2
2.8
3.60
4.02
e9/l
—
5
26
5
32
1.65
0.44
1.2
1.9
—
—
—
0
0
0
15
0.00
0.42
0.0
1.0
—
—
—
0
0
0
15
0.00
0.42
0.0
3.3
—
19.87
—
0
15
0
16
0.00
0.42
0.0
2.9
—
0.69
—
0
16
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
0
17
0.00
0.42
0.0
2.8
—
25.58
—
0
17
0
17
0.00
0.42
0.0
1.4
—
—
—
0
0
15
119
1.46
0.41
2.5
3.9
—
—
—
0
0
35
332
+∞
0.41
43.0
24.1
7.30
6.70
e9/l
0.94
35
323
35
332
+∞
0.41
42.8
24.1
4.30
4.41
e12/l
0.63
35
324
5
36
1.45
0.40
1.2
4.0
57.40
65.01
e9/l
—
5
28
21
180
1.42
0.37
12.0
9.6
4.17
4.11
e9/l
0.05
21
153
10
129
0.69
0.37
1.7
2.3
—
—
—
0
0
6
46
1.37
0.35
1.3
1.3
—
—
—
0
0
8
63
1.35
0.31
1.4
1.5
0.79
1.11
mg/l
—
8
54
17
144
1.35
0.30
12.5
6.4
56.52
57.98
%
0.18
17
138
5
40
1.29
0.23
1.0
1.5
—
—
—
0
0
0
11
0.00
0.22
0.0
3.3
—
7.77
—
0
11
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
10.1
—
—
—
0
0
0
12
0.00
0.21
0.0
3.1
—
27.48
—
0
12
0
13
0.00
0.21
0.0
3.3
—
1.32
—
0
13
16
140
1.26
0.20
4.3
4.3
19.96
34.19
ng/l
—
9
107
8
69
1.21
0.18
6.8
5.1
0.49
1.99
ug/l
—
8
63
6
74
0.77
0.18
4.8
5.0
—
—
—
0
0
5
44
1.16
0.10
1.4
1.2
—
—
—
0
0
5
46
1.10
0.10
1.6
4.3
105.00
103.09
mmol/l
—
5
46
10
106
0.92
0.01
2.5
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
65.40
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
7.44
—
0
5
0
5
0.00
0.00
0.0
2.4
—
4.01
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
17.38
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
7.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
167.60
—
0
5
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
26.60
—
0
5
0
5
0.00
0.00
0.0
1.6
—
1.80
—
0
5
8
81
0.98
0.00
6.6
3.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
87
0.90
-0.00
1.1
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
4.07
—
0
7
0
7
0.00
-0.00
0.0
3.1
—
1.21
—
0
7
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
105.43
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
1.63
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_FLATBACK and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_FLATBACK.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_FLATBACK – Flatback syndrome

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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