≡ Risteys
R14

Documentation Changelog GitHub Contact & Feedback

Other specified/unspecified nutritional deficiencies

EFO MESH Endpoint Browser PheWeb

E4_NUTRI_DEF_NAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E63.8, E63.9, E63.9+I43.2
  • Hospital discharge: ICD-9 — 269[3-9]
  • Hospital discharge: ICD-8 — 2699
  • Hospital discharge: excluded ICD-8 — 26990
  • Cause of death: ICD-10 — E63.8, E63.9, E63.9+I43.2
  • Cause of death: ICD-9 — 269[3-9]
  • Cause of death: ICD-8 — 2699
  • Cause of death: excluded ICD-8 — 26990

2 out of 7 registries used, show all original rules.

289

4. Check minimum number of events

None

289

5. Include endpoints

None

289

6. Filter based on genotype QC (FinnGen only)

260

Control definitions (FinnGen only)

Control exclude
E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2818 1684 1106
Only index persons 2159 1300 859
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 33.04 38.23 24.56
Only index persons 25.04 32.24 14.14

-FinnGen-

Key figures

All Female Male
Number of individuals 260 158 102
Unadjusted period prevalence (%) 0.05 0.06 0.05
Median age at first event (years) 26.07 24.36 28.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
272
Matched controls
2720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
26998
ICD-8 Finland
Other nutritional deficiency, Aliae definitae
+∞
225.7
184
*
K90.0
ICD-10 Finland
Coeliac disease
18.3
65.0
56
38
26999
ICD-8 Finland
Other nutritional deficiency, Other and unspecified
+∞
47.3
44
*
E63.9
ICD-10 Finland
Nutritional deficiency, unspecified
+∞
23.3
22
*
Y0599
ICD-8 Finland
Investigation of digestive system
19.3
22.5
34
20
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
79.3
20.0
22
*
26900
ICD-8 Finland
Other nutritional deficiency, Sprue and steatorrhoea
+∞
16.8
16
*
E63.8
ICD-10 Finland
Other specified nutritional deficiencies
+∞
15.8
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
14.1
106
511
26910
ICD-8 Finland
Other nutritional deficiency, Malabsorption syndrome, unspecified
136.0
12.5
13
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
9.3
46
174
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
8.4
8
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.5
8.4
21
50
A03CA02
ATC
clidinium and psycholeptics; oral
3.9
8.2
25
69
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
7.8
69
347
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
4.7
7.3
17
38
56419
ICD-8 Finland
Functional disorders of intestines, Colon irritabile aliud sive NUD
30.9
7.2
9
*
A07EC02
ATC
mesalazine; oral, rectal
3.6
7.0
24
72
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
6.7
38
154
127
Kela drug reimbursment
Transplant complication
10.4
6.6
12
12
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.5
67
357
55130
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Diaphragmatic
71.5
6.5
7
*
28009
ICD-8 Finland
Iron deficiency anaemias, Unspecified
18.5
6.3
9
5
B01AA03
ATC
warfarin; systemic
2.2
6.2
56
282
UJF32
NOMESCO Finland
Coloscopy
2.0
6.0
75
428

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
100
567
2.21
8.54
3.1
2.1
2.62
2.91
mg/l
0.74
83
497
149
1036
1.97
6.94
3.5
2.5
74.76
76.60
nmol/l
0.37
138
941
51
241
2.37
6.55
3.5
2.7
1.73
1.72
%
0.02
40
224
63
349
2.05
5.42
3.2
2.6
2.37
2.30
g/l
0.39
58
327
39
178
2.39
5.38
3.6
2.4
71.28
68.45
e9/l
0.21
29
131
87
545
1.88
5.22
4.1
2.7
339.68
335.70
umol/l
0.12
77
476
149
1114
1.75
4.84
14.8
7.0
1.22
1.22
mmol/l
0.04
127
956
104
712
1.75
4.55
8.3
4.3
7.40
7.40
ph
0.30
90
513
137
1014
1.71
4.51
25.6
12.5
1.36
1.21
inr
2.13
126
849
137
1023
1.68
4.29
8.3
4.3
35.47
35.99
g/l
0.59
126
957
36
179
2.17
4.07
13.3
7.9
—
—
—
0
0
56
328
1.89
4.04
1.7
1.3
—
—
—
0
0
59
352
1.86
4.03
2.3
1.7
1095.05
1169.62
nmol/l
0.25
42
261
35
175
2.15
3.90
5.6
4.4
105.63
95.03
ng/l
0.23
30
155
87
594
1.68
3.72
1.7
1.3
3.04
1.63
u/ml
0.35
24
162
150
1178
1.61
3.64
8.5
5.9
0.58
0.56
e9/l
0.43
130
1014
39
210
2.00
3.59
5.8
3.6
7.38
7.39
ph
0.19
24
129
150
1184
1.60
3.52
8.6
5.9
0.04
0.04
e9/l
0.14
129
1018
94
663
1.64
3.51
2.0
1.7
18.11
22.04
nmol/l
1.71
84
570
42
235
1.93
3.46
5.1
2.4
32.97
34.82
u/l
0.11
35
197
96
683
1.63
3.46
4.2
3.0
—
—
—
0
0
138
1071
1.59
3.46
9.1
6.0
2.81
2.81
%
0.01
130
1002
138
1073
1.58
3.42
9.1
6.1
8.60
8.73
%
0.23
130
1009
46
268
1.86
3.36
1.6
1.3
—
—
—
0
0
204
1745
1.68
3.35
12.8
7.9
83.35
76.56
u/l
1.01
196
1655
10
23
4.47
3.34
5.7
4.4
—
—
—
0
0
46
269
1.85
3.32
2.3
2.2
11.58
7.65
umol/l
0.45
38
239
162
1313
1.58
3.31
13.3
10.0
4.05
4.02
e9/l
0.08
140
1149
67
439
1.70
3.30
5.6
3.4
1858.21
221.73
ng/l
0.72
54
334
153
1225
1.57
3.29
8.9
6.2
0.19
0.19
e9/l
0.22
137
1070
137
1073
1.56
3.23
9.2
6.0
0.68
0.68
%
0.06
129
1001
101
740
1.58
3.17
10.8
5.5
—
—
—
0
0
139
1095
1.55
3.17
9.1
6.1
26.33
27.44
%
0.56
132
1038
45
266
1.83
3.14
2.1
1.7
—
—
—
0
0
138
1087
1.55
3.14
3.9
3.0
118.67
118.81
ug/l
0.00
130
1022
51
314
1.77
3.12
2.7
2.4
66.77
113.28
ug/g
1.69
39
259
137
1080
1.54
3.09
8.2
6.0
57.54
57.68
%
0.05
130
1029
12
36
3.44
3.06
2.4
1.2
—
—
—
0
0
76
532
1.59
2.86
1.7
1.4
2.50
2.47
g/l
0.05
40
331
148
1200
1.51
2.85
8.8
5.9
1.82
1.79
e9/l
0.15
136
1061
128
1008
1.51
2.82
12.7
6.0
1.21
1.21
mmol/l
0.01
120
923
64
432
1.63
2.78
3.1
2.8
518.07
529.68
mosm/kgh2o
0.16
57
381
25
128
2.05
2.65
6.3
3.4
7.42
7.42
ph
0.07
19
106
123
971
1.49
2.63
4.7
3.6
6.36
6.21
ph
0.66
69
561
111
859
1.49
2.61
6.6
4.1
124.30
99.11
e6/l
0.08
84
602
99
749
1.51
2.60
5.8
3.3
31.30
136.06
e6/l
0.63
81
575
73
517
1.56
2.59
4.4
2.7
5.52
5.68
e6/l
0.04
66
475
93
699
1.50
2.50
2.9
2.0
120.95
214.42
u/l
1.87
85
666
17
76
2.32
2.50
4.6
4.0
515.20
297.69
mg/l
—
5
35
82
601
1.52
2.48
5.8
4.2
—
—
—
0
0
19
90
2.19
2.45
1.2
1.3
—
—
—
0
0
24
126
1.99
2.39
1.1
1.3
—
—
—
0
0
8
22
3.71
2.38
2.4
1.5
17.70
41.03
ng/l
—
8
22
22
112
2.05
2.38
2.6
2.4
0.61
0.64
%
0.18
22
112
18
85
2.20
2.34
6.6
3.6
—
—
—
0
0
33
195
1.79
2.32
4.9
4.5
1.93
0.54
%
0.58
14
52
33
196
1.78
2.28
4.9
4.8
0.00
0.12
%
1.49
13
50
53
360
1.59
2.23
5.1
3.1
2.88
2.60
e6/l
0.08
27
185
34
206
1.74
2.20
4.9
4.6
1.14
0.83
%
0.24
14
60
146
1219
1.43
2.20
5.2
4.0
0.00
0.01
estimate
0.50
32
261
35
214
1.73
2.20
10.7
7.5
95.98
95.97
%
0.01
35
207
9
30
3.07
2.17
1.7
1.1
—
—
—
0
0
90
691
1.45
2.13
10.4
6.1
—
—
—
0
0
38
240
1.68
2.13
10.5
6.9
1.69
0.95
mmol/l
0.73
33
196
15
69
2.24
2.08
1.7
2.6
—
—
—
0
0
171
1478
1.42
2.07
7.3
4.7
4363.60
605.70
e6/l
—
5
37
84
640
1.45
2.06
5.6
3.1
0.18
0.42
e6/l
1.94
64
466
13
267
0.46
2.04
1.0
1.6
—
—
—
0
0
38
243
1.66
2.04
10.4
6.9
5.43
5.04
kpa
1.87
38
232
10
38
2.69
2.02
3.8
3.3
4.52
4.48
e9/l
—
10
38
7
21
3.39
1.98
1.7
1.8
—
—
—
0
0
11
45
2.51
1.95
3.0
1.9
62.27
61.92
%
0.02
11
45
143
1208
1.39
1.92
5.2
3.9
0.00
0.00
estimate
0.50
32
259
37
239
1.63
1.91
10.7
7.0
7.40
7.42
ph
0.60
22
142
33
208
1.67
1.88
1.5
1.2
—
—
—
0
0
20
108
1.92
1.87
15.3
6.5
15.24
15.97
%
0.49
20
102
6
17
3.58
1.84
1.2
1.0
—
—
—
0
0
194
1734
1.41
1.81
5.7
4.4
14.93
14.71
pmol/l
0.50
179
1605
13
60
2.23
1.81
2.4
2.4
2.71
1.82
index
—
7
33
17
88
1.99
1.79
2.4
1.7
18.34
4.14
ug/l
0.55
17
81
119
984
1.37
1.79
2.9
2.0
94.11
96.43
pmol/l
0.21
76
499
177
1561
1.38
1.77
4.4
3.2
64.71
43.68
u/l
1.38
167
1475
62
459
1.45
1.75
1.8
1.7
122449376.22
442.67
pmol/l
0.49
49
388
59
435
1.46
1.70
1.3
1.3
4.39
7.92
u/ml
0.47
17
173
143
1224
1.35
1.70
5.3
4.0
0.00
0.00
estimate
-0.00
30
239
7
25
2.85
1.66
1.3
1.6
31.43
32.08
pg
—
7
25
14
70
2.05
1.62
1.4
1.2
212.84
284.31
miu/ml
—
7
32
5
14
3.62
1.62
1.4
1.3
158.20
97.07
pmol/l
—
5
14
122
1032
1.33
1.52
3.6
2.6
—
—
estimate
—
0
0
88
710
1.35
1.50
3.6
2.3
—
—
—
0
0
122
1034
1.33
1.49
14.7
11.0
0.00
0.00
e9/l
0.63
97
841
41
289
1.49
1.48
12.4
6.5
103.83
104.20
mmol/l
0.23
41
289
104
864
1.33
1.45
4.4
3.7
27.18
32.90
ng/l
0.45
69
589
55
413
1.42
1.44
1.9
1.8
—
—
—
0
0
23
142
1.68
1.44
4.1
3.2
4.24
4.48
pmol/l
0.87
23
128
25
158
1.64
1.43
2.8
2.1
—
—
—
0
0
44
317
1.46
1.43
2.8
1.7
—
—
—
0
0
15
81
1.90
1.43
4.5
2.6
1.70
1.41
mg/l
0.57
15
67
26
167
1.62
1.40
4.0
2.5
6.06
6.19
ph
0.30
17
113
237
2229
1.49
1.40
31.7
17.1
139.39
139.66
mmol/l
0.94
231
2181
5
17
2.98
1.36
1.0
1.0
—
—
—
0
0
17
98
1.78
1.34
2.1
1.9
—
—
—
0
0
237
2234
1.47
1.33
32.1
17.2
3.97
3.96
mmol/l
0.03
232
2180
109
923
1.30
1.31
2.2
2.2
—
—
—
0
0
66
520
1.36
1.30
1.8
1.6
0.69
1.38
mg/l
3.09
55
409
5
18
2.81
1.29
1.4
1.4
—
—
—
0
0
34
239
1.48
1.26
2.1
1.5
—
—
—
0
0
234
2207
1.43
1.24
27.9
14.9
20.95
23.01
mg/l
0.55
200
1796
61
479
1.35
1.23
1.3
1.3
19.32
31.58
iu/ml
0.96
20
152
30
208
1.50
1.19
5.7
5.0
0.00
0.20
%
—
10
51
5
20
2.53
1.15
2.2
1.8
11.84
10.85
%
—
5
20
36
262
1.43
1.13
1.7
1.6
—
—
—
0
0
7
30
2.37
1.13
1.3
1.2
—
—
—
0
0
5
21
2.41
1.09
3.6
1.6
80.66
89.56
%
—
5
21
5
21
2.41
1.09
1.4
1.7
—
—
—
0
0
7
32
2.22
1.09
1.0
1.1
—
—
—
0
0
95
808
1.27
1.07
3.7
3.2
2.35
2.36
mmol/l
0.16
84
736
29
205
1.46
1.06
12.1
7.3
118.21
121.50
g/l
0.39
29
200
18
114
1.62
1.05
2.7
2.4
—
—
—
0
0
45
347
1.36
1.02
1.4
1.3
448.00
516.59
titre
—
5
82
28
199
1.45
1.00
4.1
2.8
0.05
0.83
e6/l
0.96
28
189
26
361
0.69
1.00
2.6
3.0
0.56
0.84
ug/l
1.64
15
227
43
331
1.36
0.99
1.6
1.6
—
—
—
0
0
5
23
2.20
0.98
1.2
1.3
—
—
—
0
0
10
54
1.88
0.98
4.0
4.2
1.61
1.20
mmol/l
—
10
45
239
2283
1.39
0.97
22.1
13.4
—
—
—
0
0
19
125
1.56
0.97
3.4
4.2
—
—
—
0
0
24
167
1.48
0.96
1.4
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
—
—
0
0
6
28
2.17
0.92
2.5
2.7
—
—
—
0
0
6
28
2.17
0.92
3.8
2.3
—
—
—
0
0
6
30
2.02
0.87
1.3
1.4
—
—
—
0
0
6
30
2.02
0.87
1.3
1.4
—
—
—
0
0
6
30
2.02
0.87
1.3
1.4
—
—
—
0
0
6
30
2.02
0.87
1.3
1.4
—
—
—
0
0
216
2045
1.27
0.85
7.0
5.4
1.87
1.85
mu/l
0.07
201
1901
8
45
1.80
0.85
8.4
2.2
—
—
—
0
0
6
31
1.96
0.85
1.2
1.5
—
—
—
0
0
10
57
1.78
0.85
3.8
2.9
60.80
60.99
%
—
10
57
25
181
1.42
0.83
13.9
4.2
7.39
7.33
ph
1.39
20
125
8
46
1.76
0.83
2.3
1.6
—
—
—
0
0
86
744
1.23
0.81
5.7
3.2
6.70
7.61
mmol/l
1.09
75
631
8
47
1.72
0.81
3.8
2.6
10.82
6.91
pmol/l
—
8
47
37
288
1.33
0.81
1.4
1.4
—
—
—
0
0
65
546
1.25
0.80
4.4
5.0
—
—
—
0
0
64
537
1.25
0.80
5.3
4.2
1.01
1.02
kg/l
2.71
47
363
13
82
1.61
0.79
2.4
1.6
—
7.89
—
0
17
82
708
1.23
0.79
5.9
4.0
11.09
6.58
mg/mmol
0.41
50
434
0
26
0.00
0.79
0.0
1.5
—
0.31
—
0
19
0
26
0.00
0.79
0.0
1.5
—
6.49
—
0
19
0
26
0.00
0.79
0.0
1.5
—
2.83
—
0
18
0
27
0.00
0.78
0.0
1.5
—
—
—
0
0
5
24
2.10
0.75
2.2
2.1
—
—
—
0
0
58
485
1.25
0.75
3.4
2.8
2.45
2.45
mmol/l
0.00
46
437
80
694
1.22
0.73
5.6
3.3
44.02
40.30
mg/l
0.07
53
443
5
25
2.02
0.73
2.0
2.4
—
—
—
0
0
13
193
0.66
0.72
1.5
1.8
3.51
3.49
mmol/l
—
7
138
7
40
1.77
0.72
7.4
2.2
2.07
2.48
mmol/l
—
7
25
24
178
1.38
0.71
4.1
3.6
—
—
—
0
0
243
2348
1.33
0.71
33.9
19.1
80.18
76.29
umol/l
0.75
238
2320
104
928
1.20
0.71
4.8
3.8
0.04
0.05
estimate
0.04
25
221
5
93
0.53
0.68
3.6
3.1
163.80
2606.73
u/ml
—
5
84
242
2340
1.31
0.68
17.7
11.4
26.65
25.57
u/l
0.47
236
2282
15
104
1.47
0.64
3.1
2.1
0.50
0.00
estimate
—
6
41
36
291
1.27
0.62
1.9
1.4
—
—
—
0
0
8
50
1.62
0.62
1.4
1.6
—
—
—
0
0
18
131
1.40
0.61
1.3
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
79.00
—
0
21
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
18
133
1.38
0.56
3.2
7.1
24.20
24.84
mmol/l
0.40
18
126
6
37
1.64
0.56
4.7
4.3
104.17
105.37
mmol/l
—
6
32
6
37
1.64
0.56
4.7
4.3
12.83
10.62
mmol/l
—
6
32
8
126
0.62
0.55
1.4
1.9
—
—
—
0
0
15
109
1.40
0.52
1.1
1.1
—
—
—
0
0
76
678
1.17
0.51
5.9
4.0
0.00
0.01
estimate
0.74
27
244
215
2074
1.17
0.47
7.5
6.0
40.31
38.91
mmol/mol
1.27
200
1964
7
48
1.47
0.47
2.6
1.8
—
—
—
0
0
7
51
1.38
0.44
1.1
1.2
—
—
—
0
0
76
686
1.15
0.44
4.0
3.4
0.00
0.01
estimate
0.74
27
203
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
5.4
—
8.22
—
0
18
88
953
0.89
0.38
2.2
1.9
1.40
1.35
mmol/l
0.23
71
811
20
161
1.26
0.38
1.2
1.2
—
—
—
0
0
13
98
1.34
0.38
1.2
1.2
—
—
—
0
0
245
2400
1.21
0.37
40.1
23.0
252.73
250.09
e9/l
0.23
240
2359
245
2401
1.21
0.36
40.0
23.1
6.75
6.59
e9/l
0.63
239
2349
245
2401
1.21
0.36
40.0
23.0
4.39
4.48
e12/l
2.33
239
2352
10
134
0.74
0.36
1.2
1.1
—
—
—
0
0
12
91
1.33
0.34
8.3
3.4
25.04
24.89
mmol/l
0.08
12
91
24
201
1.21
0.33
3.4
2.1
0.00
0.00
estimate
—
5
52
20
241
0.82
0.33
1.1
1.4
—
—
—
0
0
14
111
1.28
0.30
1.5
1.5
0.48
0.28
mg/l
—
6
51
215
2099
1.12
0.28
5.8
4.8
5.99
5.88
mmol/l
0.52
198
1951
8
64
1.26
0.27
1.3
1.1
—
—
—
0
0
9
77
1.17
0.24
2.6
1.5
—
—
—
0
0
212
2073
1.10
0.24
4.9
4.1
1.33
1.24
mmol/l
0.67
199
1923
20
173
1.17
0.21
1.2
1.3
397.80
126.52
u/ml
—
5
76
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
8.54
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
55
589
0.92
0.20
4.0
5.0
1.70
2.75
ug/l
1.03
47
530
6
51
1.18
0.19
3.2
1.6
4.58
4.90
mmol/24h
—
6
45
7
58
1.21
0.18
1.7
1.9
—
—
—
0
0
7
63
1.11
0.17
3.0
2.7
1.39
1.68
mmol/l
—
7
63
8
68
1.18
0.16
1.3
1.2
—
—
—
0
0
8
71
1.13
0.16
1.0
1.3
515.50
476.06
mg/l
—
8
65
6
78
0.76
0.16
1.2
1.3
—
—
—
0
0
9
79
1.14
0.15
1.4
1.2
—
—
—
0
0
7
87
0.80
0.15
5.0
4.1
1.19
0.81
%
—
7
81
21
189
1.12
0.14
1.4
1.3
—
—
—
0
0
89
924
0.95
0.14
3.3
3.1
—
—
—
0
0
59
616
0.95
0.11
1.4
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.10
1.0
1.0
12.34
0.34
u/ml
—
5
16
5
45
1.11
0.10
1.2
1.2
154.00
234.75
u/ml
—
5
26
5
46
1.09
0.09
1.2
1.1
—
15.31
—
0
16
6
55
1.09
0.09
3.0
5.0
—
—
—
0
0
21
195
1.08
0.08
1.7
1.7
—
—
—
0
0
7
64
1.10
0.08
1.0
1.2
5.24
3.68
mmol/l
—
7
56
7
65
1.08
0.08
3.1
2.0
—
—
—
0
0
7
84
0.83
0.07
1.0
1.1
1.49
1.53
g/l
—
7
84
224
2226
1.04
0.05
6.2
5.5
2.69
2.76
mmol/l
0.54
213
2082
218
2194
0.97
0.05
5.7
4.9
4.63
4.69
mmol/l
0.40
209
2060
24
233
1.03
0.01
1.7
1.7
—
—
—
0
0
10
98
1.02
0.00
2.4
1.5
—
—
—
0
0
10
99
1.01
0.00
5.5
3.9
1.71
1.43
%
—
10
93
219
2189
1.00
0.00
5.5
4.8
1.45
1.48
mmol/l
0.53
208
2049
10
97
1.03
0.00
2.4
1.5
—
—
—
0
0
10
97
1.03
0.00
2.4
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
45.50
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
6.0
—
10.67
—
0
6
0
6
0.00
0.00
0.0
2.7
—
3100.67
—
0
6
0
6
0.00
0.00
0.0
2.8
—
1.82
—
0
6
0
6
0.00
0.00
0.0
1.0
—
0.02
—
0
6
6
63
0.95
-0.00
1.2
1.2
0.67
13.72
e6/l
—
6
46
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
98
0.92
-0.00
2.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
10.54
—
0
5
8
87
0.92
-0.00
1.0
1.1
1.05
0.91
g/l
—
8
87
7
73
0.96
-0.00
1.1
1.3
—
2.66
—
0
9
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.2
22.00
186.86
e6/l
—
6
49
9
92
0.98
-0.00
2.6
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.16
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
57.60
—
0
5
7
78
0.89
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.20
—
0
5
5
49
1.02
-0.00
2.4
2.8
6.66
7.76
mmol/l
—
5
49
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.22
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint E4_NUTRI_DEF_NAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_NUTRI_DEF_NAS 3.366 [2.28, 4.96] < 0.001
Birth year 0.992 [0.98, 1.0] 0.064

During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 230 females with E4_NUTRI_DEF_NAS died.

Males

Parameter HR [95% CI] p-value
E4_NUTRI_DEF_NAS 4.555 [2.46, 8.43] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 157 males with E4_NUTRI_DEF_NAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_NUTRI_DEF_NAS.

N-year risk Females Males
1 0.247% 0.866%
5 1.609% 5.4%
10 4.136% 12.203%
15 8.068% 22.754%
20 14.903% 35.897%

Relationships between endpoints

↥

Index endpoint: E4_NUTRI_DEF_NAS – Other specified/unspecified nutritional deficiencies

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data