No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
233 |
4. Check minimum number of eventsNone |
233 |
5. Include endpointsNone |
233 |
6. Filter based on genotype QC (FinnGen only) |
201 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M72
Similar endpoints
↥List of similar endpoints to
Necrotizing fasciitis
based on the number of shared cases.
Similar with more cases:
- Fibroblastic disorders
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 969 | 395 | 574 |
| Only index persons | 953 | 390 | 563 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | - | 66.29 | 56.91 |
| Only index persons | 60.76 | 66.30 | 56.93 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 201 | 78 | 123 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 64.49 | 68.83 | 61.73 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 207
- Matched controls
- 2070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M72.6
ICD-10 Finland
Necrotizing fasciitis
+∞
296.4
206
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
72.1
167.5
97
25
TQW11
NOMESCO Finland
Vacuum treatment of wound
78.3
130.2
72
14
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
64.6
105.4
60
13
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
29.1
104.8
79
43
ZZA00
NOMESCO Finland
Split skin graft
34.0
99.7
69
30
A46
ICD-10 Finland
Erysipelas
17.1
99.5
132
193
S97
ICPC
Chronic ulcer skin
18.8
88.6
85
74
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
13.2
81.2
128
226
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
22.1
64.8
52
31
TPH07
NOMESCO Finland
Cathetrisation of artery
10.5
57.2
81
119
SPAT1148
SPAT
Treatment of chronic ulcer or burn
9.4
53.1
84
140
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
17.1
51.0
46
34
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.5
50.5
57
61
A41.9
ICD-10 Finland
Sepsis, unspecified
15.7
46.7
44
35
QDA10
NOMESCO Finland
Incision of skin of lower limb
120.9
44.9
47
5
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
16.3
43.8
40
30
ZXD05
NOMESCO Finland
Urgent procedure
5.9
36.7
120
390
WX402
NOMESCO Finland
General anaesthesia
5.9
35.4
98
274
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.9
34.3
90
239
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
7.8
33.5
55
92
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
9.6
32.8
43
55
S18
ICPC
Laceration/cut
6.1
31.9
156
688
A10AB05
ATC
insulin aspart; parenteral
7.9
31.1
49
78
WX872
NOMESCO Finland
Intensive care
9.0
30.0
41
55
N17.9
ICD-10 Finland
Acute renal failure, unspecified
12.0
29.7
32
31
J01FF01
ATC
clindamycin; systemic
4.9
28.4
98
320
QBA10
NOMESCO Finland
Incision of skin of trunk
55.7
28.4
33
7
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.1
28.4
61
133
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
9.9
26.5
33
39
C03CA01
ATC
furosemide; systemic
4.5
26.0
110
415
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
6.1
25.8
53
110
A10AE04
ATC
insulin glargine; parenteral
6.1
25.5
53
111
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
8.0
24.2
36
53
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
6.6
23.6
43
79
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.7
23.0
51
113
Z3231
NOMESCO Finland
Registered nurse
4.1
21.9
92
337
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
9.3
21.0
27
33
WX320
NOMESCO Finland
Spinalanesthesy
4.1
21.0
82
284
WX730
NOMESCO Finland
Conventional respirator
54.0
20.6
24
5
R4120
NOMESCO Finland
Occupational therapy
7.1
20.1
33
54
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.9
18.4
48
121
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.0
18.3
45
108
N03AX16
ATC
[U] pregabalin
3.9
17.7
68
229
R4110
NOMESCO Finland
Physiotherapy
3.6
17.7
90
366
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
6.3
17.6
32
58
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.0
17.5
43
103
N02AA05
ATC
oxycodone; systemic
3.9
17.4
65
215
NFQ20
NOMESCO Finland
Amputation of femur
69.3
17.0
19
*
L17
ICPC
Foot/toe symptom/complaint
3.5
16.8
87
356
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
16.5
52
151
T90
ICPC
Diabetes non-insulin dependent
3.5
16.4
82
327
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
16.2
52
153
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
16.2
81
323
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
7.6
16.1
24
35
L03.9
ICD-10 Finland
Cellulitis, unspecified
21.4
16.0
23
12
A40.0
ICD-10 Finland
Sepsis due to streptococcus, group A
+∞
15.8
15
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
15.7
132
714
SPAT1149
SPAT
Suture or treatment of traumatic wound
4.2
15.7
50
146
S76
ICPC
Skin infection other
6.0
15.7
30
57
SPAT1255
SPAT
Intravenous administration of medicine
5.8
15.6
31
61
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
31.4
15.5
20
7
NHQ40
NOMESCO Finland
Amputation of toe
25.8
15.5
21
9
L28
ICPC
Limited function/disability (L)
3.7
15.4
61
208
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
15.4
72
274
103
Kela drug reimbursment
Diabetes, insulin-treated
3.3
15.3
88
380
JFF23
NOMESCO Finland
Transversostomy
18.3
15.2
23
14
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
18.3
15.2
23
14
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.3
15.0
83
349
A28
ICPC
Limited function/disability NOS
3.6
14.9
62
218
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.2
14.7
27
49
ZXA05
NOMESCO Finland
Left side
3.4
14.7
70
268
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.8
14.6
29
57
ZXE10
NOMESCO Finland
More than one and less than three hours
3.1
14.4
100
479
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
46.1
14.3
17
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
17.4
14.3
22
14
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
5.3
14.1
31
67
ZXE00
NOMESCO Finland
One hour or less
3.0
13.8
102
503
N02AX02
ATC
tramadol; systemic, rectal
3.0
13.8
107
542
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.1
13.6
31
69
ZXA00
NOMESCO Finland
Right side
3.1
13.5
79
341
J01CF05
ATC
flucloxacillin; systemic
4.8
13.3
33
79
SPAT1151
SPAT
Treatment of major wounds
24.5
13.1
18
8
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.7
13.1
26
51
WX002
NOMESCO Finland
Sedation and analgesia
3.4
13.0
58
212
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.5
12.8
53
184
M79.6
ICD-10 Finland
Pain in limb
2.9
12.8
93
450
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
138.0
12.6
13
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
12.3
74
321
L03.3
ICD-10 Finland
Cellulitis of trunk
28.7
12.2
16
6
WX892
NOMESCO Finland
Monitored bed care
4.9
12.1
29
67
C03DA01
ATC
spironolactone; oral
3.7
12.1
44
140
WX213
NOMESCO Finland
Lower leg blockade
49.7
12.0
14
*
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
49.7
12.0
14
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.4
11.9
50
175
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
10.2
11.9
23
25
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
32.1
11.8
15
5
Z93.3
ICD-10 Finland
Colostomy status
20.4
11.8
17
9
SPAT1262
SPAT
Handing over of treatment supplies
3.2
11.6
56
213
I48.1
ICD-10 Finland
Persistent atrial fibrillation
5.9
11.6
22
41
C07AB07
ATC
bisoprolol; oral
2.8
11.5
127
752
I50.9
ICD-10 Finland
Heart failure, unspecified
3.4
11.5
49
173
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.0
11.4
21
38
T89
ICPC
Diabetes insulin dependent
6.0
11.4
21
38
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.4
11.3
31
80
A10AE05
ATC
insulin detemir; parenteral
5.1
11.3
25
54
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.9
11.1
73
330
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
5.5
10.8
22
44
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.4
10.7
29
74
TK800
NOMESCO Finland
Hemodialysis
11.5
10.5
19
18
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.3
10.5
45
159
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.8
10.4
25
58
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
5.5
10.3
21
42
C08CA01
ATC
amlodipine; oral
2.6
10.3
106
597
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
10.9
10.3
19
19
Z2221
NOMESCO Finland
Medical doctor
2.8
10.2
68
308
A10AC01
ATC
insulin (human); parenteral
4.2
10.2
29
77
N05AH04
ATC
quetiapine; oral
3.1
10.1
51
198
205
Kela drug reimbursment
Chronic hypertension
2.8
10.0
67
304
X59
ICD-10 Finland
Exposure to unspecified factor
3.0
10.0
53
212
Z3226
NOMESCO Finland
Physiotherapist
3.1
9.8
49
189
WX306
NOMESCO Finland
Lumbar epidural anesthesy
7.8
9.8
22
31
B01AB10
ATC
tinzaparin; parenteral
3.5
9.8
37
120
A10BJ06
ATC
semaglutide; parenteral
5.0
9.8
22
48
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
12.2
9.8
17
15
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
57.8
9.7
11
*
J01DB01
ATC
cefalexin; oral
3.8
9.7
183
1380
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.6
9.6
22
32
J01MA12
ATC
levofloxacin; systemic
2.9
9.6
55
229
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
5.6
9.6
19
37
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
18.6
9.5
14
8
A10BA02
ATC
metformin; oral
2.6
9.5
80
405
R60.0
ICD-10 Finland
Localized oedema
3.4
9.5
38
128
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
23.0
9.5
13
6
XF600
NOMESCO Finland
Bloodpressure measurement
4.5
9.5
24
58
A48.0
ICD-10 Finland
Gas gangrene
+∞
9.4
9
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.6
9.4
35
112
N02BF01
ATC
gabapentin; oral
4.4
9.4
25
63
E0000UV, ,
ATC
2.5
9.3
101
576
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
9.3
71
343
N03AX12
ATC
[U] gabapentin; oral
3.2
9.2
41
147
B01AB05
ATC
enoxaparin; parenteral
2.5
9.2
81
418
J01MA02
ATC
ciprofloxacin; systemic
2.5
9.2
95
528
WZC30
NOMESCO Finland
Teaching
2.9
9.2
51
208
N06AX21
ATC
duloxetine; oral
3.9
9.2
29
83
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.3
9.1
38
131
NGM10
NOMESCO Finland
Fasciotomy of of knee or lower leg
38.5
9.1
11
*
QCA10
NOMESCO Finland
Incision of skin of upper limb
38.5
9.1
11
*
A02BC02
ATC
pantoprazole; systemic
2.7
9.0
153
1064
B01AF02
ATC
apixaban; oral
3.1
8.9
42
156
AA1AD
NOMESCO Finland
CT of head and brain
2.5
8.9
79
409
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
8.3
8.9
19
25
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
7.9
8.7
19
26
TKC20
NOMESCO Finland
Catheterisation of bladder
4.0
8.5
25
68
A10BB12
ATC
glimepiride; oral
4.0
8.5
25
68
JN4AD
NOMESCO Finland
Body CT examination
3.1
8.4
40
149
QDB10, ,
SPAT
8.1
8.4
18
24
H02AB06
ATC
prednisolone; systemic
2.3
8.3
107
648
A06AD11
ATC
lactulose; oral
3.0
8.3
41
156
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
8.3
30
94
R02
ICPC
Shortness of breath/dyspnoea
3.2
8.2
36
128
Z2446
NOMESCO Finland
Social worker
4.0
8.2
24
65
TQW40
NOMESCO Finland
Remowal of suture of skin
4.0
8.2
24
65
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
34.8
8.2
10
*
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
34.8
8.2
10
*
PE1AT
NOMESCO Finland
Femoral artery PTA
23.1
8.1
11
5
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
8.1
98
577
N02BF02
ATC
pregabalin; oral
4.8
8.1
19
43
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.5
8.1
30
96
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.1
8.0
23
61
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
8.0
28
86
A10BJ02
ATC
liraglutide; parenteral
7.5
8.0
18
26
WX203
NOMESCO Finland
Infraclavicular plexus blockade
11.5
7.9
14
13
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
11.5
7.9
14
13
ZX120
NOMESCO Finland
Intravenous
3.5
7.9
29
92
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
4.7
7.9
19
44
XF400
NOMESCO Finland
ECG with 12 standard connections
2.8
7.9
45
186
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
46.8
7.8
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
7.7
85
479
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.6
7.7
52
234
A40.8
ICD-10 Finland
Other streptococcal sepsis
12.5
7.7
13
11
WX212
NOMESCO Finland
Femoral plexus blockade
10.6
7.7
14
14
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
26.1
7.6
10
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.2
7.6
32
111
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.6
7.5
26
79
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
7.5
42
171
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
14.1
7.5
12
9
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
14.1
7.5
12
9
ZXD35
NOMESCO Finland
Usual procedure
6.7
7.4
18
29
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
7.4
94
559
OAB50, ,
SPAT
3.5
7.4
27
85
WX750
NOMESCO Finland
Hyperbaric oxygen therapy
+∞
7.3
7
*
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
+∞
7.3
7
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.5
7.3
18
30
E66.01
ICD-10 Finland
Obesity due to excess calories
3.6
7.2
25
76
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
20.9
7.2
10
5
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
10.6
7.1
13
13
L89
ICD-10 Finland
Decubitus ulcer and pressure area
10.6
7.1
13
13
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.6
7.1
24
72
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
4.4
7.0
18
44
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
7.1
7.0
16
24
L14
ICPC
Leg/thigh symptom/complaint
3.6
6.9
24
73
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.8
6.9
22
63
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.4
6.9
59
295
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.3
6.9
27
89
ZXA10
NOMESCO Finland
Bilateral
2.6
6.9
46
205
N02BE01
ATC
paracetamol; systemic, rectal
3.8
6.9
191
1572
A41.8
ICD-10 Finland
Other specified sepsis
7.6
6.8
15
21
ZZR00
NOMESCO Finland
Flap of skin
7.6
6.8
15
21
NGQ20
NOMESCO Finland
Amputation of lower leg
17.4
6.8
10
6
ZZR30
NOMESCO Finland
Flap of muscle
41.4
6.8
8
*
SPAT1211
SPAT
Application of soft bandage
3.3
6.8
27
90
CKC12
NOMESCO Finland
Photocoagulation of retina
4.3
6.8
18
45
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.8
6.7
37
149
N18.8
ICD-10 Finland
Other chronic renal failure
8.3
6.7
14
18
R60.9
ICD-10 Finland
Oedema, unspecified
4.1
6.7
19
50
M04AA01
ATC
allopurinol; systemic
2.8
6.7
38
156
EBA15
NOMESCO Finland
Extraction of multiple teeth
5.7
6.6
18
34
A10BD07
ATC
metformin and sitagliptin; systemic
5.7
6.6
18
34
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
6.1
6.6
17
30
WX704
NOMESCO Finland
Intubation
3.4
6.5
24
76
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
6.5
73
409
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
6.5
44
197
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.9
6.5
15
23
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
14.9
6.5
10
7
TNG34
NOMESCO Finland
Major custom moulded orthopaedic cast, knee or lower leg
14.9
6.5
10
7
J96.0
ICD-10 Finland
Acute respiratory failure
14.9
6.5
10
7
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
14.9
6.5
10
7
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
72.0
6.5
7
*
H3603, E103,
ICD-10 Finland
72.0
6.5
7
*
R50.9
ICD-10 Finland
Fever, unspecified
2.6
6.4
41
178
WX882
NOMESCO Finland
High dependency care
8.6
6.4
13
16
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
6.4
26
88
A01
ICPC
Pain general/multiple sites
3.2
6.4
26
88
L04AA06
ATC
mycophenolic acid; systemic
11.5
6.4
11
10
GD1AD
NOMESCO Finland
Thorax CT examination
3.8
6.3
20
57
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
7.4
6.3
14
20
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
6.3
74
421
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
18.7
6.3
9
5
R4190
NOMESCO Finland
Nutritional therapy
6.1
6.3
16
28
S51.0
ICD-10 Finland
Open wound of elbow
27.6
6.3
8
*
I50.0
ICD-10 Finland
Congestive heart failure
3.3
6.3
24
78
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
8.1
6.2
13
17
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
7.1
6.1
14
21
P01AB01
ATC
metronidazole; oral, rectal
2.1
6.1
82
490
A10BX07
ATC
[U] liraglutide
13.1
6.1
10
8
GBB00
NOMESCO Finland
Tracheostomy
10.5
6.1
11
11
E66.00
ICD-10 Finland
Metabolic syndrome
3.9
6.1
18
49
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
6.1
42
190
B35.3
ICD-10 Finland
Tinea pedis
5.3
6.0
17
34
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.5
6.0
41
184
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
50
38
17.03
54.79
2.2
1.5
—
—
—
0
0
105
225
8.44
52.97
16.7
10.7
5.24
5.06
kpa
0.83
105
211
105
225
8.44
52.97
16.7
10.7
11.77
12.43
kpa
0.66
105
214
73
104
10.30
52.50
13.1
9.4
23.66
24.82
mmol/l
1.01
73
104
104
224
8.32
52.09
15.8
10.7
0.97
0.83
mmol/l
0.08
95
184
51
44
15.05
51.87
3.3
1.4
—
—
—
0
0
94
189
8.28
49.97
17.7
12.1
109.87
121.24
g/l
4.23
94
182
79
132
9.06
49.56
17.2
11.2
93.60
93.26
%
0.13
79
132
112
302
6.90
43.57
4.2
4.0
0.79
0.81
mmol/l
1.29
107
289
105
289
6.34
39.26
2.5
2.0
—
—
—
0
0
89
211
6.65
39.04
2.5
1.8
—
—
—
0
0
99
272
6.06
36.70
17.9
7.7
103.64
104.49
mmol/l
0.74
99
272
88
220
6.22
36.13
2.5
1.7
—
—
—
0
0
59
109
7.17
32.73
20.0
16.0
14.40
15.85
%
2.67
59
100
75
185
5.79
30.68
6.7
3.3
1.31
1.55
mmol/l
0.15
65
158
72
172
5.89
30.50
2.8
2.2
0.17
0.22
g/l
5.48
67
159
71
179
5.52
28.09
7.5
3.4
—
—
—
0
0
54
109
6.35
27.12
5.7
3.1
23.63
23.79
mmol/l
0.09
54
109
158
774
5.40
26.41
5.9
2.8
—
—
estimate
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
37
52
8.45
25.93
3.2
2.2
0.34
0.40
iu/ml
0.20
21
24
59
137
5.62
25.40
2.5
1.6
—
—
—
0
0
119
495
4.30
24.14
5.5
3.0
1.24
0.34
e6/l
1.52
96
365
105
412
4.14
22.84
5.1
2.5
—
—
—
0
0
133
633
4.08
21.52
6.3
3.1
—
—
—
0
0
103
424
3.84
20.41
3.2
2.1
3.49
3.07
mg/l
0.83
94
361
160
891
4.50
20.06
20.9
8.1
1.16
1.21
mmol/l
8.96
150
764
174
1058
5.04
18.63
18.1
5.5
8.06
6.73
mmol/l
7.03
174
1014
26
36
8.12
18.24
3.4
1.6
63.03
63.91
%
0.06
26
36
166
991
4.41
17.85
16.1
10.5
6.04
4.22
e9/l
5.58
148
872
45
113
4.81
17.27
5.1
2.5
0.61
0.65
%
0.28
45
113
45
115
4.72
16.88
5.0
2.6
1.34
1.12
%
0.86
45
115
46
129
4.30
15.25
16.5
9.7
25.11
24.35
mmol/l
0.54
46
119
29
55
5.97
15.15
1.3
1.2
—
—
—
0
0
170
1098
4.07
14.76
7.5
4.2
—
1021.11
—
0
19
96
449
3.12
14.38
3.6
2.9
396.58
357.85
umol/l
1.98
84
392
75
305
3.29
14.25
4.5
2.8
0.91
1.20
e6/l
0.47
43
163
25
24
11.68
13.68
1.5
1.0
—
—
—
0
0
25
24
11.68
13.68
1.5
1.0
—
—
—
0
0
37
95
4.52
13.67
1.8
1.3
—
—
—
0
0
37
95
4.52
13.67
2.0
1.8
—
—
—
0
0
25
29
9.65
12.43
4.1
2.6
15.08
16.54
%
1.00
25
29
126
725
2.89
12.39
5.0
2.8
267.09
148.22
ug/l
0.80
118
663
103
540
2.81
12.01
3.4
3.5
4275.92
1224.85
ng/l
2.29
98
461
111
612
2.75
11.63
5.9
3.3
6.10
8.13
mmol/l
6.99
103
515
67
283
3.02
11.62
4.7
2.9
2.71
2.47
e6/l
0.08
36
145
78
366
2.82
11.08
2.4
1.5
1.69
1.62
mg/l
0.07
67
280
144
921
2.85
11.04
6.2
3.5
30.86
0.00
estimate
0.49
43
187
144
926
2.82
10.84
6.2
3.5
0.00
0.02
estimate
0.50
38
176
22
28
8.66
10.42
5.7
3.8
4.83
5.00
kpa
0.40
22
28
141
909
2.73
10.35
6.2
3.5
0.00
0.00
estimate
-0.00
41
187
105
590
2.58
10.21
5.9
4.1
36.96
8.75
mg/mmol
2.05
82
372
68
321
2.67
9.32
6.0
3.8
168.92
429.18
ng/l
0.89
63
260
53
227
2.79
8.71
2.6
1.8
2.07
1.51
%
1.64
47
201
37
129
3.27
8.71
6.8
3.5
151.29
82.64
ng/l
2.03
32
114
116
728
2.35
8.31
2.4
2.1
91.77
96.00
pmol/l
0.37
73
384
22
55
4.36
8.30
2.0
1.2
—
—
—
0
0
17
23
7.95
7.85
2.7
2.0
2.04
1.50
mmol/l
1.48
17
23
19
46
4.45
7.45
4.4
3.4
2.36
3.74
index
0.38
11
27
21
56
4.06
7.28
1.5
1.8
—
—
—
0
0
20
52
4.15
7.17
1.5
1.6
—
—
—
0
0
21
57
3.99
7.11
1.9
2.8
1.48
3.29
ratio
—
9
32
22
63
3.79
6.93
1.9
3.0
35.33
58.75
mg/l
0.34
15
53
22
63
3.79
6.93
1.9
2.9
61.03
63.51
mg/l
0.03
16
53
17
40
4.54
6.89
1.4
1.1
—
—
—
0
0
17
40
4.54
6.89
4.2
2.0
115.41
135.44
g/l
2.65
17
32
112
734
2.15
6.74
3.0
2.4
70.82
77.57
nmol/l
1.60
105
653
17
41
4.43
6.69
1.4
1.1
—
—
—
0
0
18
36
5.37
6.35
1.6
1.3
—
—
—
0
0
13
17
8.08
6.22
2.3
2.8
89.45
89.79
%
0.08
13
17
11
11
10.48
6.11
1.8
1.3
—
—
—
0
0
28
103
2.99
5.98
5.0
4.2
3.67
1.68
mmol/l
2.21
16
83
14
22
6.74
5.97
2.5
3.4
30.43
33.23
pg
1.47
14
22
24
84
3.10
5.57
2.7
1.7
0.31
0.29
mg/l
0.08
14
42
19
60
3.39
5.18
2.7
2.5
—
—
—
0
0
53
286
2.15
5.05
2.0
1.6
1373.62
1166.86
nmol/l
0.61
46
212
81
512
1.96
5.00
7.5
3.8
0.00
0.02
estimate
0.74
37
177
19
63
3.22
4.81
1.4
1.3
—
—
—
0
0
91
607
1.89
4.72
3.8
3.5
2.30
2.35
mmol/l
1.85
85
555
60
348
2.02
4.69
1.3
1.3
0.70
1.41
u/ml
1.00
15
100
15
36
4.41
4.62
2.3
1.3
—
—
—
0
0
60
350
2.01
4.61
3.7
2.9
2.47
2.45
mmol/l
0.57
52
321
8
8
10.34
4.56
2.0
1.3
93.50
95.00
%
—
8
8
30
133
2.47
4.48
3.4
3.0
49.72
58.65
ml/min/173m2
0.45
18
54
10
16
6.51
4.35
1.2
1.1
—
—
—
0
0
39
198
2.19
4.29
6.4
2.8
5.67
7.12
umol/l
0.57
34
182
155
1255
1.94
4.11
7.5
3.8
25.17
12.03
mm/h
7.42
145
1152
7
7
10.29
4.04
1.9
2.3
9.14
13.57
%
—
7
7
14
37
3.98
3.98
1.4
2.0
—
—
—
0
0
8
11
7.51
3.89
3.6
2.6
1059.88
1019.27
u/ml
—
8
11
12
28
4.48
3.88
1.5
1.5
—
—
—
0
0
7
8
9.00
3.80
1.9
2.3
—
—
—
0
0
13
34
4.01
3.76
5.2
3.9
11.65
10.64
pmol/l
0.13
13
34
97
699
1.73
3.65
5.6
3.8
70.66
43.32
ng/l
0.95
86
517
10
21
4.95
3.60
1.3
1.1
—
—
u/ml
—
0
0
14
46
3.19
3.60
1.6
1.6
—
—
—
0
0
7
9
8.00
3.58
1.1
1.2
664.00
301.30
iu/ml
—
7
9
11
26
4.41
3.56
1.5
1.4
—
—
—
0
0
6
6
10.25
3.52
1.0
1.0
—
—
—
0
0
13
43
3.16
3.31
1.5
1.6
—
—
—
0
0
13
39
3.49
3.29
1.6
1.7
—
—
—
0
0
9
20
4.65
3.15
1.4
1.3
—
—
—
0
0
169
1455
1.88
3.11
65.3
18.9
14.80
13.62
%
16.24
169
1439
8
16
5.15
3.08
1.8
1.4
—
—
—
0
0
6
8
7.68
3.07
1.5
1.1
—
—
—
0
0
6
9
6.82
2.88
1.5
1.0
—
—
—
0
0
6
9
6.82
2.88
1.8
1.8
—
—
—
0
0
95
713
1.61
2.87
7.0
3.5
0.00
0.03
estimate
0.68
32
157
14
53
2.76
2.86
1.1
1.3
—
—
—
0
0
95
719
1.59
2.74
2.3
1.9
1.80
1.38
mmol/l
1.53
84
593
195
1793
2.51
2.59
72.1
18.3
138.15
139.69
mmol/l
11.20
195
1753
54
360
1.68
2.57
1.6
1.8
779.72
38361081.92
pmol/l
0.50
47
305
11
37
3.08
2.53
13.6
18.9
103.82
104.13
mmol/l
0.08
11
30
195
1796
2.48
2.53
72.6
18.5
4.06
3.99
mmol/l
2.80
195
1751
8
21
3.92
2.49
1.3
1.4
—
—
—
0
0
123
1004
1.55
2.46
3.5
2.8
—
—
—
0
0
35
209
1.81
2.43
21.3
8.0
—
—
—
0
0
6
12
5.11
2.42
3.2
1.3
143303.67
40411.43
e6/l
—
6
7
10
33
3.13
2.39
1.4
1.6
—
—
—
0
0
8
22
3.74
2.39
1.5
1.4
—
—
—
0
0
12
47
2.65
2.31
2.3
1.4
—
—
—
0
0
12
47
2.65
2.31
1.2
1.7
—
—
—
0
0
7
18
3.99
2.27
1.7
3.3
—
—
—
0
0
7
18
3.99
2.27
1.6
4.2
2559.00
996.72
mg
—
7
18
10
37
2.79
2.10
1.5
1.2
186.40
312.96
u/ml
—
5
23
6
15
4.09
2.05
1.8
1.0
—
—
—
0
0
56
397
1.56
2.05
9.4
3.8
1.02
1.02
kg/l
0.54
40
264
10
38
2.71
2.03
1.1
1.3
289.00
328.37
ug/g
—
5
25
9
196
0.43
1.97
2.3
2.1
3.72
3.65
ratio
—
9
160
10
39
2.64
1.97
1.4
1.2
—
—
—
0
0
5
11
4.63
1.95
1.2
1.8
—
—
—
0
0
6
16
3.83
1.95
1.7
2.3
0.50
0.88
index
—
6
16
36
238
1.62
1.75
1.2
1.2
1.53
18.92
u/ml
2.16
12
92
5
13
3.91
1.72
1.8
3.7
1.00
1.08
%
—
5
13
6
20
3.06
1.59
6.0
2.3
—
—
—
0
0
6
21
2.91
1.51
1.2
1.3
105.33
105.71
%
—
6
21
145
1290
1.41
1.47
4.2
3.9
14.92
14.98
pmol/l
0.12
139
1147
7
28
2.55
1.46
1.4
1.2
—
—
—
0
0
5
17
2.99
1.36
1.6
1.1
—
—
—
0
0
170
1566
1.48
1.34
5.4
4.8
1.98
1.98
mu/l
0.00
164
1408
9
43
2.14
1.32
2.0
1.4
—
—
—
0
0
6
24
2.54
1.31
1.2
1.2
—
—
—
0
0
33
454
0.68
1.26
2.8
3.1
0.67
0.85
ug/l
0.41
23
280
195
1860
1.83
1.23
69.4
20.2
95.23
81.32
umol/l
2.36
195
1838
5
19
2.67
1.22
2.4
1.2
—
—
—
0
0
5
19
2.67
1.22
1.4
2.1
—
—
—
0
0
5
19
2.67
1.22
1.4
2.1
—
—
—
0
0
5
19
2.67
1.22
1.4
2.1
—
—
—
0
0
180
1691
1.49
1.14
55.9
14.8
79.22
80.46
ml/min/173m2
0.22
174
1578
28
195
1.50
1.12
4.5
5.0
41.80
63.63
ug/l
0.16
22
164
7
31
2.30
1.11
1.6
1.1
—
—
—
0
0
7
31
2.30
1.11
1.1
1.0
—
1.25
—
0
6
64
522
1.33
1.05
5.6
2.9
0.00
0.01
estimate
0.50
33
145
49
612
0.74
1.05
4.0
4.6
22.82
21.16
%
0.22
18
276
7
135
0.50
1.02
1.9
1.9
2.69
3.64
mmol/l
—
7
100
5
23
2.20
0.98
1.0
2.3
—
—
—
0
0
5
23
2.20
0.98
1.0
2.3
—
—
—
0
0
6
27
2.26
0.94
1.3
1.1
—
—
—
0
0
6
29
2.10
0.90
1.7
1.2
—
—
—
0
0
6
30
2.03
0.87
1.0
1.2
—
8.67
—
0
6
34
261
1.36
0.83
1.4
1.2
49.27
43.99
iu/ml
—
9
77
9
56
1.63
0.73
3.7
2.1
—
—
—
0
0
191
1846
1.45
0.68
26.3
11.6
31.28
27.94
u/l
0.63
191
1790
5
28
1.80
0.66
1.0
1.3
—
1.00
—
0
5
33
265
1.29
0.62
1.3
1.4
—
—
—
0
0
12
80
1.53
0.61
1.4
2.7
35.58
38.21
u/l
0.16
12
71
0
23
0.00
0.58
0.0
1.3
—
184.01
—
0
23
18
133
1.39
0.57
2.1
1.9
—
—
—
0
0
19
145
1.34
0.51
1.6
1.4
—
—
—
0
0
195
1904
1.42
0.50
80.4
23.1
91.66
91.19
fl
0.65
195
1883
195
1904
1.42
0.50
85.4
23.7
36.66
40.93
%
18.89
195
1880
195
1904
1.42
0.50
80.6
23.1
4.11
4.55
e12/l
16.56
195
1858
195
1905
1.41
0.48
81.5
23.3
120.99
137.45
g/l
26.38
195
1882
68
756
0.85
0.48
4.7
5.3
2.21
2.68
ug/l
0.26
58
680
7
49
1.44
0.46
4.0
2.0
—
—
—
0
0
13
172
0.74
0.42
1.1
1.5
—
—
—
0
0
5
32
1.58
0.42
1.0
1.3
—
—
—
0
0
8
59
1.37
0.41
1.6
2.3
—
—
—
0
0
0
17
0.00
0.41
0.0
3.4
—
19.17
—
0
6
180
1752
1.21
0.36
5.6
5.0
4.23
4.59
mmol/l
4.47
163
1615
182
1776
1.21
0.34
6.6
5.7
2.37
2.70
mmol/l
5.33
165
1631
179
1746
1.19
0.32
5.4
5.0
1.28
1.42
mmol/l
3.94
161
1593
18
147
1.25
0.32
2.2
2.0
—
—
—
0
0
5
38
1.32
0.23
1.0
1.3
—
2.48
—
0
10
7
91
0.76
0.23
1.6
1.7
46.14
39.42
nmol/l
—
7
91
172
1685
1.12
0.21
4.9
4.3
1.55
1.31
mmol/l
2.23
154
1532
0
12
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
11.50
—
0
12
6
53
1.14
0.19
1.7
2.0
—
—
—
0
0
6
53
1.14
0.19
1.5
1.6
—
—
—
0
0
172
1690
1.10
0.17
5.8
5.0
7.40
6.02
mmol/l
6.55
158
1539
5
46
1.09
0.09
1.0
1.1
—
3.18
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
1.6
2.5
27.63
58.65
u/ml
—
8
76
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
69.83
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1.02
—
0
7
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_NECROFASC and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_NECROFASC | 4.252 [2.17, 8.33] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.118 |
During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 352 males with M13_NECROFASC died.
Mortality risk
Mortality risk for people of age
years, who have M13_NECROFASC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.782% |
| 5 | No data | 4.842% |
| 10 | No data | 13.347% |
| 15 | No data | 24.441% |
| 20 | No data | 38.97% |
Relationships between endpoints
↥Index endpoint: M13_NECROFASC – Necrotizing fasciitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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