No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
746 |
4. Check minimum number of eventsNone |
746 |
5. Include endpointsNone |
746 |
6. Filter based on genotype QC (FinnGen only) |
653 |
Control definitions (FinnGen only)
- Control exclude
- H7_LENS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H27
- Name in latin
- Aphakia
Aphakia
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10286 | 5262 | 4814 |
| Only index persons | 5128 | 2468 | 2660 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.15 | 0.13 |
| Only index persons | 0.10 | 0.09 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 63.75 | 67.32 | 59.82 |
| Only index persons | 53.87 | 59.58 | 48.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 653 | 248 | 405 |
| Unadjusted period prevalence (%) | 0.15 | 0.09 | 0.19 |
| Median age at first event (years) | 57.56 | 57.83 | 57.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 677
- Matched controls
- 6764
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H27.0
ICD-10 Finland
Aphakia
+∞
307.7
442
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
60.1
307.7
215
52
Z96.1
ICD-10 Finland
Presence of intraocular lens
64.2
307.7
292
79
H25.1
ICD-10 Finland
Senile nuclear cataract
40.4
304.2
195
67
S01ED51
ATC
timolol, combinations; ophthalmic
22.7
280.2
232
152
WX140
NOMESCO Finland
Parabulbar anesthesy
41.5
247.7
155
48
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
209.5
190
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
49.8
208.2
123
30
S01ED01
ATC
timolol; ophthalmic
23.1
206.7
161
90
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
9.2
191.0
394
889
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
101.4
184.7
96
11
H33.0
ICD-10 Finland
Retinal detachment with retinal break
43.1
183.2
112
31
114
Kela drug reimbursment
Glaucoma
12.1
177.7
212
246
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
+∞
170.1
156
*
S01EC01
ATC
acetazolamide; systemic
35.5
147.7
95
31
CJB10
NOMESCO Finland
Laser discission of secondary cataract
81.6
136.4
73
10
S01EA05
ATC
brimonidine; ophthalmic
32.9
135.3
89
31
S01EE01
ATC
latanoprost; ophthalmic
12.1
120.9
133
134
CKD60
NOMESCO Finland
Anterior vitrectomy
408.7
105.3
103
*
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
1073.3
97.5
93
*
37402
ICD-8 Finland
Cataract, Senilis
+∞
92.9
87
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.4
92.3
135
195
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
35.1
90.7
58
18
H26.4
ICD-10 Finland
After-cataract
188.6
81.1
83
5
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.4
79.6
195
468
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
+∞
78.7
74
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
106.3
77.9
84
9
S01EC04
ATC
brinzolamide; ophthalmic
13.8
74.6
72
58
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
185.4
65.2
67
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
31.9
63.9
42
14
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.6
61.3
108
188
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
12.3
61.2
63
56
H25.8
ICD-10 Finland
Other senile cataract
226.9
61.2
62
*
S01EX03, ,
ATC
13.4
60.5
59
48
3631
FHL
Setting up an artificial lens as the only procedure
+∞
59.2
56
*
3661A
ICD-9 Finland
Cataract, Senile cataract
+∞
58.1
55
*
37401
ICD-8 Finland
Cataract, Praesenilis
+∞
57.1
54
*
S01BC05
ATC
ketorolac; ophthalmic
16.4
56.7
49
32
XCH00
NOMESCO Finland
Eye pressure measurement
11.4
56.6
61
58
XCK00
NOMESCO Finland
Perimetry
8.7
55.9
75
96
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.5
55.3
337
1506
37403
ICD-8 Finland
Cataract, Complicata
299.5
55.0
55
*
37404
ICD-8 Finland
Cataract, Secundaria
+∞
52.8
50
*
S01BA07
ATC
fluorometholone; ophthalmic
18.3
52.7
43
25
H43.1
ICD-10 Finland
Vitreous haemorrhage
16.9
50.7
43
27
S01BC03
ATC
diclofenac; ophthalmic
15.5
50.6
45
31
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
8.0
49.1
70
96
H27.1
ICD-10 Finland
Dislocation of lens
+∞
48.5
46
*
S01BA04
ATC
prednisolone; ophthalmic
12.2
47.8
49
43
S01BA01
ATC
dexamethasone; ophthalmic
8.7
46.3
61
76
H40.0
ICD-10 Finland
Glaucoma suspect
5.9
45.0
88
168
TCG10
NOMESCO Finland
Removal of sutures from cornea
+∞
43.2
41
*
S01EE03
ATC
bimatoprost; ophthalmic
14.2
41.9
39
29
S01EA03
ATC
apraclonidine; ophthalmic
57.2
41.0
48
9
XCK10
NOMESCO Finland
Photography of fundus of eye
5.0
40.6
97
221
37405
ICD-8 Finland
Cataract, Traumatica
+∞
40.0
38
*
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
15.3
39.3
35
24
Z94.7
ICD-10 Finland
Corneal transplant status
212.0
39.2
40
*
S01AX11
ATC
[U] ofloxacin
7.8
38.2
55
76
S01EE05
ATC
tafluprost; ophthalmic
8.4
36.6
49
62
37520
ICD-8 Finland
Glaucoma, Secondary
195.2
36.1
37
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
7.5
35.6
53
76
Q12.0
ICD-10 Finland
Congenital cataract
365.0
35.3
35
*
S01EC03
ATC
dorzolamide; ophthalmic
13.8
35.0
33
25
H20.1
ICD-10 Finland
Chronic iridocyclitis
97.7
34.1
37
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
97.7
34.1
37
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
39.5
32.8
41
11
H25.0
ICD-10 Finland
Senile incipient cataract
10.8
32.7
36
35
WX142
NOMESCO Finland
Sub-tenon anesthesy
57.3
32.6
38
7
H16.0
ICD-10 Finland
Corneal ulcer
6.1
32.6
59
104
S01FA01
ATC
atropine; ophthalmic
41.3
31.5
39
10
H26.2
ICD-10 Finland
Complicated cataract
+∞
31.5
30
*
H18.1
ICD-10 Finland
Bullous keratopathy
327.0
31.1
31
*
ZXA05
NOMESCO Finland
Left side
2.9
30.3
182
762
Z3229
NOMESCO Finland
Other healthcare associate professional
4.0
30.0
93
258
CKD20
NOMESCO Finland
Removal of vitreous body substitute
111.7
29.9
32
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
162.0
29.9
31
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
162.0
29.9
31
*
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
+∞
29.4
28
*
3625
FHL
Extracapsular nuclear cataract removal
+∞
29.4
28
*
WX002
NOMESCO Finland
Sedation and analgesia
3.1
28.8
144
543
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
37.9
28.6
36
10
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
10.1
27.8
32
33
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
10.8
27.3
30
29
3642
FHL
Anterior vitrectomy
+∞
27.3
26
*
CJW99
NOMESCO Finland
Other operation on lens
+∞
27.3
26
*
S01EE04
ATC
travoprost; ophthalmic
10.1
26.9
31
32
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.5
26.6
53
102
ZXA00
NOMESCO Finland
Right side
2.7
26.6
193
884
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
+∞
26.2
25
*
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
+∞
26.2
25
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
75.4
26.0
29
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
270.2
25.9
26
*
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
97.2
25.8
28
*
ZXA10
NOMESCO Finland
Bilateral
3.3
25.7
109
371
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
+∞
25.1
24
*
3643
FHL
Vitrectomy through pars Plana
259.0
24.8
25
*
ZXD20
NOMESCO Finland
Day surgery
3.4
24.2
96
313
CG2T4
NOMESCO Finland
Topography assessment of cornea
70.0
24.0
27
*
H54.4
ICD-10 Finland
Blindness, monocular
129.5
23.7
25
*
S01EB01
ATC
pilocarpine; ophthalmic
24.7
23.7
33
14
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
226.8
21.7
22
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.0
21.6
27
31
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
24.1
21.4
30
13
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.5
21.0
53
125
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
79.3
20.8
23
*
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
79.3
20.8
23
*
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
113.4
20.7
22
*
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
113.4
20.7
22
*
3639
FHL
Other measure in this category
+∞
19.9
19
*
CGF10
NOMESCO Finland
Suture of laceration of cornea
+∞
19.9
19
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
19.9
19
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
19.9
19
*
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
+∞
18.8
18
*
3745
FHL
Hard membrane girding, cerclage with coagulation
71.9
18.8
21
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
71.9
18.8
21
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
19.4
18.8
28
15
CKD15
NOMESCO Finland
Injection of vitreous substitute
102.8
18.6
20
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
195.0
18.6
19
*
H17.8
ICD-10 Finland
Other corneal scars and opacities
195.0
18.6
19
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
22.4
18.3
26
12
37601
ICD-8 Finland
Detachment of retina, Secundaria
+∞
17.8
17
*
CKC70
NOMESCO Finland
Circular buckling of sclera
97.6
17.6
19
*
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
184.5
17.6
18
*
H57.1
ICD-10 Finland
Ocular pain
5.2
17.3
36
72
H26.02
ICD-10 Finland
Presenil cataract
+∞
16.7
16
*
H26.1
ICD-10 Finland
Traumatic cataract
92.3
16.6
18
*
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
7.3
16.2
24
34
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
15.8
73
259
H17.1
ICD-10 Finland
Other central corneal opacity
61.5
15.8
18
*
CJE00
NOMESCO Finland
Phakoemulsification
+∞
15.7
15
*
3665A
ICD-9 Finland
Cataract, After-cataract
+∞
15.7
15
*
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
+∞
15.7
15
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
6.2
15.7
27
45
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
87.1
15.6
17
*
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
87.1
15.6
17
*
37600
ICD-8 Finland
Detachment of retina, Primaria
87.1
15.6
17
*
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
163.5
15.5
16
*
XCW10
NOMESCO Finland
Assessment of vision
16.5
15.3
24
15
H50.1
ICD-10 Finland
Divergent concomitant strabismus
29.3
15.3
20
7
37400
ICD-8 Finland
Cataract, Infantilis, juvenilis
+∞
14.6
14
*
CJF20
NOMESCO Finland
Removal of artificial lens
+∞
14.6
14
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
81.9
14.6
16
*
H3603, E103,
ICD-10 Finland
81.9
14.6
16
*
S01AD03
ATC
aciclovir; ophthalmic
5.0
14.6
32
67
H40.9
ICD-10 Finland
Glaucoma, unspecified
10.4
14.1
27
27
S01FA04
ATC
cyclopentolate; ophthalmic
13.0
14.0
24
19
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
76.7
13.6
15
*
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
13.6
13
*
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
+∞
13.6
13
*
3660C
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA PRAESENILIS]
+∞
13.6
13
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
13.6
13
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
142.6
13.5
14
*
S01ED02
ATC
betaxolol; ophthalmic
14.2
13.3
22
16
S01AA01
ATC
chloramphenicol; ophthalmic
3.6
13.3
44
127
CKC30
NOMESCO Finland
Cryopexy of detached retina
40.9
13.2
16
*
S01FA02
ATC
scopolamine; ophthalmic
15.4
13.2
21
14
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
23.0
12.9
18
8
CG2S4
NOMESCO Finland
Photography of cornea
51.0
12.9
15
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
12.8
78
321
A10AA01, ,
ATC
5.3
12.8
26
51
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
12.7
224
1403
3621
FHL
In the aftermath of the dissection
+∞
12.5
12
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
18.4
12.1
18
10
CKC60
NOMESCO Finland
Local buckling of sclera using implant
27.2
12.1
16
6
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
27.2
12.1
16
6
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
9.2
11.8
24
27
CFD10
NOMESCO Finland
Repair of conjunctiva
66.1
11.6
13
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
66.1
11.6
13
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
11.6
88
401
3624
FHL
Extracapsular soft cataract removal
+∞
11.5
11
*
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
+∞
11.5
11
*
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
11.5
11
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
121.9
11.5
12
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
11.4
228
1477
H16.9
ICD-10 Finland
Keratitis, unspecified
8.5
11.4
24
29
ZXE00
NOMESCO Finland
One hour or less
1.8
11.3
222
1429
H18.6
ICD-10 Finland
Keratoconus
35.6
11.3
14
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
17.4
11.2
17
10
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
3.6
11.1
37
107
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
5.7
10.7
20
36
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
60.9
10.6
12
*
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
60.9
10.6
12
*
36409
ICD-8 Finland
Iritis, Unspecified
60.9
10.6
12
*
H18.4
ICD-10 Finland
Corneal degeneration
60.9
10.6
12
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
60.9
10.6
12
*
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
111.6
10.4
11
*
3604
FHL
Penetration of the cornea
111.6
10.4
11
*
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
+∞
10.4
10
*
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
10.4
10
*
3627
FHL
Intracapsular cataract surgery
+∞
10.4
10
*
37409
ICD-8 Finland
Cataract, Unspecified
+∞
10.4
10
*
A10AB01
ATC
insulin (human); parenteral
4.0
10.4
29
74
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.4
10.4
22
27
Z3231
NOMESCO Finland
Registered nurse
1.9
10.3
171
1040
H40
ICD-10 Finland
Glaucoma
12.4
9.9
17
14
H25.9
ICD-10 Finland
Senile cataract, unspecified
20.4
9.8
14
7
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
20.4
9.8
14
7
H44.2
ICD-10 Finland
Degenerative myopia
55.8
9.7
11
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
4.5
9.6
23
52
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
15.3
9.5
15
10
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
9.4
42
146
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
101.3
9.4
10
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
101.3
9.4
10
*
H33.5
ICD-10 Finland
Other retinal detachments
17.8
9.4
14
8
H33.4
ICD-10 Finland
Traction detachment of retina
30.5
9.4
12
*
3768
FHL
Eye examination under general anesthesia
+∞
9.4
9
*
CGF45
NOMESCO Finland
Suture of laceration of sclera
+∞
9.4
9
*
Q87.4
ICD-10 Finland
Marfan syndrome
+∞
9.4
9
*
CHE30
NOMESCO Finland
Suture of iris
+∞
9.4
9
*
H17.0
ICD-10 Finland
Adherent leukoma
+∞
9.4
9
*
3623
FHL
Extracapsular cataract aspiration
+∞
9.4
9
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.1
9.4
26
66
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
22.0
9.4
13
6
CHC05
NOMESCO Finland
Iridotomy
11.7
9.1
16
14
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.7
9.1
28
77
J01MA02
ATC
ciprofloxacin; systemic
1.7
9.0
250
1752
H33.2
ICD-10 Finland
Serous retinal detachment
37.2
9.0
11
*
3503
FHL
Single muscle retroposition
37.2
9.0
11
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
24.4
8.9
12
5
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
8.8
357
2748
H54.0
ICD-10 Finland
Blindness, binocular
50.6
8.7
10
*
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
50.6
8.7
10
*
H18.8
ICD-10 Finland
Other specified disorders of cornea
16.5
8.6
13
8
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
27.9
8.5
11
*
Z97.0
ICD-10 Finland
Presence of artificial eye
91.1
8.4
9
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
91.1
8.4
9
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
91.1
8.4
9
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
8.3
124
725
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
8.3
8
*
3662A
ICD-9 Finland
Cataract, Traumatic cataract
+∞
8.3
8
*
CJF99
NOMESCO Finland
Other operation on artificial lens
+∞
8.3
8
*
3714A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal degenerations
+∞
8.3
8
*
37100
ICD-8 Finland
Corneal opacity, Cicatrix (nubecula, macula, leucoma) cornea
+∞
8.3
8
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
8.3
8
*
3649
FHL
Other measure in this category
+∞
8.3
8
*
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
+∞
8.3
8
*
3719
FHL
Other measure in this category
+∞
8.3
8
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
8.3
8
*
E9179
ICD-8 Finland
Striking against or struck accidentally by objects
4.6
8.2
19
42
CKC10
NOMESCO Finland
Local photocoagulation of retina
6.9
8.1
19
28
87001
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Non complicata (sive NUD)
33.7
8.1
10
*
37898
ICD-8 Finland
Other diseases of eye, Disease of eyeball, ocular muscle and orbit NEC
22.3
8.0
11
5
A10AE04
ATC
insulin glargine; parenteral
2.3
7.8
63
294
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
7.8
207
1424
XCH05
NOMESCO Finland
Eye pressure longterm registration
11.0
7.8
14
13
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
6.0
7.7
20
34
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
45.5
7.7
9
*
H54.7
ICD-10 Finland
Unspecified visual loss
18.6
7.6
11
6
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
18.6
7.6
11
6
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
3.5
7.6
26
77
L84
ICD-10 Finland
Corns and callosities
3.6
7.5
24
68
3700A
ICD-9 Finland
Keratitis, Corneal ulcer
80.9
7.4
8
*
A10AC01
ATC
insulin (human); parenteral
2.2
7.4
60
281
WX402
NOMESCO Finland
General anaesthesia
1.8
7.3
112
659
3711
FHL
Cyclodiateria or cryocoagulation
+∞
7.3
7
*
H26.00
ICD-10 Finland
Infantile, juvenile and presenile cataract
+∞
7.3
7
*
3660A
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA INFANTILIS]
+∞
7.3
7
*
3606
FHL
Keratophakic corneal surgery
+∞
7.3
7
*
T85.3
ICD-10 Finland
Mechanical complication of other ocular prosthetic devices, implants and grafts
+∞
7.3
7
*
3660B
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA JUVENILIS]
+∞
7.3
7
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
7.3
7
*
3793B
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[DISLOCATIO LENTIS]
+∞
7.3
7
*
CJD30
NOMESCO Finland
Pars plana lensectomy
+∞
7.3
7
*
H02AB06
ATC
prednisolone; systemic
1.6
7.3
273
2035
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
15.9
7.2
11
7
127
Kela drug reimbursment
Transplant complication
7.4
7.2
16
22
H21.0
ICD-10 Finland
Hyphaema
30.3
7.2
9
*
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
12.2
7.1
12
10
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
8.9
7.1
14
16
WX199
NOMESCO Finland
Other local analgesia
4.3
7.0
18
43
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.0
6.9
30
103
CKC12
NOMESCO Finland
Photocoagulation of retina
3.6
6.9
22
62
ZXD05
NOMESCO Finland
Urgent procedure
1.6
6.9
177
1203
A10AB05
ATC
insulin aspart; parenteral
2.4
6.9
45
192
C03CA01
ATC
furosemide; systemic
1.6
6.8
252
1865
S01AA12
ATC
tobramycin; ophthalmic
11.1
6.8
12
11
H26.9
ICD-10 Finland
Cataract, unspecified
11.1
6.8
12
11
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
6.8
88
491
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
40.4
6.8
8
*
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
40.4
6.8
8
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
16.9
6.8
10
6
A10AB04
ATC
insulin lispro; parenteral
3.6
6.8
22
63
N02BE01
ATC
paracetamol; systemic, rectal
1.6
6.7
505
4368
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
12.4
6.6
11
9
CD2S4
NOMESCO Finland
Photography of eye
12.4
6.6
11
9
3852
FHL
Reoperation for another reason
70.4
6.4
7
*
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
70.4
6.4
7
*
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.4
162
1096
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.6
6.3
17
31
A46
ICD-10 Finland
Erysipelas
1.8
6.3
97
571
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
6.3
6
*
25001
ICD-8 Finland
Diabetes mellitus, Cataracta diabetica
+∞
6.3
6
*
CJG00
NOMESCO Finland
Extraction of dislocated lens
+∞
6.3
6
*
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
6.3
6
*
3633
FHL
Cataract removal through pars Plana
+∞
6.3
6
*
37408
ICD-8 Finland
Cataract, Alia
+∞
6.3
6
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
6.3
6
*
3632
FHL
Artificial lens removal
+∞
6.3
6
*
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
+∞
6.3
6
*
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
+∞
6.3
6
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
+∞
6.3
6
*
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
+∞
6.3
6
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
+∞
6.3
6
*
H44.5
ICD-10 Finland
Degenerated conditions of globe
26.9
6.2
8
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
26.9
6.2
8
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
26.9
6.2
8
*
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.2
137
893
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
6.2
195
1388
L04AA06
ATC
mycophenolic acid; systemic
5.8
6.2
16
28
EBA00
NOMESCO Finland
Extraction of tooth
1.6
6.1
180
1259
XCD20
NOMESCO Finland
Photoangiography of eye
7.8
6.1
13
17
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.5
6.1
36
146
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
366
2685
1.79
12.24
7.6
5.1
7.26
6.77
mmol/l
2.78
348
2550
136
781
1.93
9.77
3.1
2.4
12.72
12.70
umol/l
0.01
120
723
170
1092
1.74
8.37
3.3
2.7
7.54
4.70
e6/l
1.02
161
990
306
2291
1.61
8.32
11.9
7.2
1.21
1.21
mmol/l
0.14
264
1974
115
665
1.88
7.99
3.2
2.4
22.75
22.79
%
0.01
105
617
109
640
1.84
7.19
9.7
5.4
1.11
1.02
mmol/l
2.35
102
589
178
1205
1.65
7.07
2.5
2.1
2.75
3.00
mg/l
0.77
154
1020
293
2235
1.55
6.98
18.3
16.1
1.32
1.31
inr
0.06
247
1850
276
2078
1.55
6.97
6.4
5.0
34.93
35.10
g/l
0.18
256
1933
196
1379
1.59
6.59
2.6
2.1
194.86
262.20
u/l
0.56
181
1298
117
722
1.75
6.51
3.3
2.4
2.21
2.27
g/l
0.46
103
665
215
1555
1.56
6.38
4.7
3.5
140.50
74.40
e6/l
0.27
178
1190
267
2033
1.52
6.23
10.3
6.6
1.20
1.21
mmol/l
1.05
248
1865
196
1396
1.57
6.20
3.5
2.6
93.71
117.33
u/l
0.14
187
1288
379
3107
1.50
6.14
4.3
4.0
15.15
15.00
pmol/l
0.53
337
2833
208
1505
1.55
6.12
5.2
3.9
16.07
9.15
mg/mmol
0.82
146
940
210
1527
1.54
6.03
4.6
3.2
6.53
7.76
mmol/l
4.54
184
1287
406
3384
1.50
6.00
9.8
8.1
85.55
80.71
u/l
0.64
380
3184
318
2525
1.49
5.98
10.5
9.4
4.53
4.21
e9/l
1.23
279
2185
358
2915
1.48
5.91
5.9
4.8
94.56
4242.81
e6/l
—
9
53
237
1786
1.50
5.69
4.3
3.8
97.06
92.86
ng/l
0.02
175
1326
295
2332
1.47
5.54
4.9
3.9
0.06
0.65
estimate
0.44
68
464
293
2314
1.47
5.53
4.9
3.9
0.00
3.30
estimate
0.50
73
492
126
828
1.64
5.51
1.8
1.7
1071.52
1131.06
nmol/l
0.33
98
629
289
2282
1.46
5.43
4.9
3.9
0.00
0.00
estimate
-0.00
68
483
483
4218
1.50
5.33
22.4
16.6
31.07
27.08
mg/l
0.81
424
3514
119
783
1.63
5.17
3.9
3.3
0.82
0.82
mmol/l
0.18
112
734
496
4369
1.50
5.13
27.7
20.0
139.53
139.66
mmol/l
0.51
490
4264
496
4379
1.49
4.98
28.2
20.1
4.00
3.99
mmol/l
0.11
487
4262
374
3132
1.43
4.97
5.4
4.1
14.95
13.09
mm/h
1.23
347
2913
16
46
3.54
4.91
1.3
1.4
—
—
—
0
0
442
3823
1.45
4.88
5.7
4.9
2.01
2.01
mu/l
0.00
398
3501
225
1726
1.45
4.78
5.5
4.0
237.49
138.79
e6/l
0.30
177
1230
29
120
2.48
4.77
1.6
1.8
—
—
—
0
0
244
1906
1.44
4.69
3.4
2.9
161.18
146.75
ug/l
0.31
220
1751
296
2405
1.41
4.52
7.1
6.6
14.67
11.92
umol/l
1.10
284
2297
194
1460
1.46
4.52
3.5
3.5
31.42
33.70
u/l
0.62
186
1391
180
1339
1.47
4.44
4.3
3.5
1.03
0.53
e6/l
0.63
141
978
60
340
1.84
4.44
4.5
3.8
1.22
1.23
mmol/l
0.07
53
288
452
3968
1.42
4.29
8.0
6.3
41.68
39.76
mmol/mol
3.54
414
3681
501
4482
1.45
4.27
29.6
22.0
89.32
81.76
umol/l
2.38
495
4412
87
557
1.64
4.20
2.6
4.5
223.71
258.01
u/l
2.37
82
533
195
1492
1.43
4.10
3.4
3.2
1732.88
1501.45
ng/l
0.40
171
1286
79
499
1.66
4.02
8.1
3.2
1.47
2.00
mmol/l
0.60
73
410
129
918
1.50
3.93
1.7
1.6
1.61
1.34
mg/l
0.26
100
732
69
423
1.70
3.93
4.0
2.6
66.70
66.09
g/l
0.31
64
399
260
2109
1.38
3.85
3.1
2.7
—
—
estimate
—
0
0
88
578
1.60
3.84
8.8
8.0
-0.15
0.94
mmol/l
0.99
78
476
26
114
2.33
3.82
2.0
1.2
—
—
—
0
0
220
1744
1.39
3.72
5.1
3.9
8.82
0.03
estimate
0.49
57
400
488
4393
1.39
3.64
14.8
11.8
26.63
26.47
u/l
0.05
472
4251
169
1285
1.42
3.63
5.4
4.0
0.03
0.01
estimate
0.36
59
424
64
397
1.67
3.51
2.8
2.3
7.14
7.13
ug/l
0.00
54
347
162
1236
1.41
3.40
4.3
3.2
0.04
0.13
estimate
0.55
54
376
502
4561
1.39
3.38
33.5
25.1
91.55
91.37
fl
0.39
496
4488
502
4561
1.39
3.38
33.6
25.2
245.45
243.33
e9/l
0.27
489
4443
81
538
1.57
3.38
2.1
2.6
11.26
8.59
umol/l
0.28
72
482
502
4562
1.38
3.37
34.6
25.7
39.27
40.08
%
2.28
496
4483
502
4562
1.38
3.37
33.6
25.1
4.37
4.47
e12/l
3.82
489
4429
461
4134
1.36
3.36
6.5
5.7
2.50
2.65
mmol/l
3.12
423
3807
502
4563
1.38
3.36
33.9
25.3
131.34
134.74
g/l
4.95
497
4490
74
482
1.60
3.35
9.8
8.8
119.07
120.33
g/l
0.18
74
466
200
1584
1.37
3.35
4.2
3.5
2.35
2.35
mmol/l
0.12
178
1425
69
445
1.61
3.26
2.1
2.2
0.21
0.21
g/l
0.18
64
412
447
4003
1.34
3.21
23.3
16.5
74.73
77.45
ml/min/173m2
1.74
418
3706
452
4056
1.34
3.19
5.6
5.1
4.33
4.53
mmol/l
3.85
416
3754
90
623
1.51
3.13
2.0
1.8
—
—
—
0
0
227
1850
1.34
3.13
3.3
2.3
75.74
77.00
nmol/l
0.27
205
1650
448
4032
1.33
2.99
5.5
5.0
1.38
1.43
mmol/l
1.68
408
3714
10
26
3.88
2.98
1.5
1.3
—
—
—
0
0
114
836
1.44
2.97
2.0
1.9
—
—
—
0
0
16
63
2.57
2.97
1.4
1.6
—
—
—
0
0
32
171
1.91
2.90
2.3
2.6
—
—
—
0
0
6
9
6.71
2.87
1.0
1.0
—
—
—
0
0
40
231
1.78
2.85
4.9
4.6
1.57
1.53
%
0.14
40
214
130
984
1.40
2.83
3.3
3.0
2.46
2.46
mmol/l
0.00
106
874
27
140
1.97
2.68
1.7
1.4
201.41
262.88
ug/g
0.84
20
85
54
351
1.58
2.51
2.8
3.0
65.15
64.61
ml/min/173m2
0.04
27
147
164
1316
1.32
2.45
1.9
1.7
18.95
20.10
nmol/l
0.47
142
1119
190
1557
1.30
2.44
4.4
4.6
22.90
20.95
%
1.25
110
777
82
588
1.45
2.42
2.0
1.8
—
—
—
0
0
67
462
1.50
2.40
3.5
3.4
—
—
—
0
0
27
146
1.88
2.40
3.8
3.1
5.53
2.61
ratio
0.50
12
85
9
27
3.36
2.39
1.1
1.5
—
—
—
0
0
230
1938
1.28
2.37
5.8
5.5
7.17
3.94
ug/l
0.30
206
1735
239
2024
1.28
2.37
2.4
2.1
92.33
93.91
pmol/l
0.22
140
1082
51
335
1.56
2.29
6.6
3.9
120.98
93.75
ng/l
0.61
44
288
16
72
2.25
2.28
1.4
1.3
—
—
—
0
0
444
4061
1.27
2.26
6.0
5.1
6.21
6.00
mmol/l
2.07
398
3685
425
3873
1.26
2.20
4.7
4.2
1.30
1.29
mmol/l
0.15
382
3539
39
243
1.64
2.17
7.4
3.1
25.98
25.12
mmol/l
0.64
39
230
128
1009
1.33
2.15
5.5
4.2
1.02
1.02
kg/l
0.55
90
653
7
19
3.71
2.15
3.0
4.9
—
—
—
0
0
112
866
1.35
2.14
1.3
1.3
3.22
1.12
u/ml
0.36
38
220
41
260
1.61
2.14
1.4
1.4
—
—
—
0
0
19
354
0.52
2.12
2.1
2.0
3.43
3.55
ratio
0.20
13
287
142
1140
1.31
2.10
3.4
3.3
0.80
0.80
ug/l
0.02
107
762
13
56
2.35
2.05
3.2
1.9
9.85
10.19
mmol/l
0.13
13
56
120
944
1.33
2.05
4.5
4.1
482.34
408.75
ng/l
0.16
102
781
10
38
2.65
2.01
1.3
1.3
63.00
49.64
u/l
—
10
33
28
163
1.75
2.01
4.0
3.1
75.46
78.22
mg/l
0.02
22
144
28
163
1.75
2.01
4.0
3.1
39.50
104.36
mg/l
0.47
22
145
11
46
2.41
1.85
1.5
1.6
—
—
—
0
0
107
841
1.32
1.84
4.1
3.1
1.67
1.15
e6/l
0.37
57
450
19
101
1.90
1.82
1.5
3.1
30.26
34.36
umol/l
0.34
19
92
19
101
1.90
1.82
1.3
1.6
—
—
—
0
0
100
780
1.33
1.82
4.4
3.3
2.02
2.11
e6/l
0.04
49
389
118
944
1.30
1.79
1.9
1.7
98958729.19
14942944.25
pmol/l
0.39
96
783
8
29
2.78
1.79
1.4
1.5
—
—
—
0
0
22
124
1.80
1.77
1.3
1.4
0.11
0.07
iu/ml
—
6
21
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
171
1.66
1.72
2.3
2.4
0.29
0.36
iu/ml
0.34
13
91
19
104
1.85
1.68
1.2
1.7
—
—
—
0
0
257
2265
1.22
1.67
2.9
2.8
—
—
—
0
0
14
257
0.53
1.54
1.4
1.8
3.74
3.51
mmol/l
—
7
191
20
115
1.76
1.53
2.8
2.2
128.40
130.33
g/l
0.12
15
89
41
285
1.47
1.48
12.2
10.2
15.50
15.70
%
0.17
41
272
135
1127
1.25
1.46
3.9
2.8
362.20
353.48
umol/l
0.41
115
985
33
221
1.52
1.43
1.1
1.2
243.19
148.85
u/ml
0.24
15
82
9
40
2.26
1.40
1.1
1.1
—
—
—
0
0
5
17
2.95
1.36
2.0
3.4
4.34
5.34
kpa
—
5
17
5
17
2.95
1.36
2.0
3.4
10.80
9.64
kpa
—
5
17
31
212
1.48
1.24
1.5
1.9
1.69
1.59
ug/l
0.03
25
181
13
70
1.87
1.24
2.5
2.0
964.00
5959.58
u/l
—
5
23
36
255
1.43
1.22
4.4
2.4
0.56
0.61
%
0.39
36
255
134
1141
1.22
1.21
3.0
2.3
—
—
—
0
0
55
420
1.34
1.20
3.3
3.0
272.94
201.87
ng/l
0.79
50
386
42
309
1.38
1.16
6.8
6.5
24.39
24.42
mmol/l
0.01
42
290
297
2733
1.15
1.06
3.5
3.3
58.77
52.15
u/l
0.61
284
2561
38
280
1.38
1.06
4.1
3.6
2.63
1.88
mmol/l
0.36
26
202
15
90
1.68
1.04
2.3
1.6
—
—
—
0
0
13
75
1.75
1.03
4.7
2.7
11.37
8.04
pmol/l
0.84
13
75
51
641
0.78
0.95
1.4
1.3
13.70
11.43
u/ml
0.11
22
234
19
125
1.53
0.94
2.1
1.3
1.18
1.18
g/l
0.00
19
120
7
37
1.90
0.94
1.3
1.7
—
—
—
0
0
7
37
1.90
0.94
1.3
1.7
—
—
—
0
0
7
37
1.90
0.94
1.3
1.7
—
—
—
0
0
58
466
1.27
0.91
1.8
1.8
1.51
1.54
%
0.12
52
405
18
118
1.54
0.91
1.3
1.5
—
—
—
0
0
6
29
2.08
0.89
1.2
1.3
—
—
—
0
0
6
29
2.08
0.89
1.2
1.3
—
—
—
0
0
42
325
1.31
0.88
1.7
1.7
—
—
—
0
0
43
334
1.31
0.88
2.1
1.5
—
—
—
0
0
6
31
1.94
0.84
1.2
1.4
—
—
—
0
0
31
231
1.36
0.84
1.7
1.8
1.54
1.51
g/l
0.06
26
205
19
129
1.49
0.84
1.1
1.4
—
—
—
0
0
40
312
1.30
0.81
1.5
1.5
—
—
—
0
0
32
243
1.33
0.78
2.5
3.7
1.02
1.02
ratio
0.50
23
229
18
123
1.47
0.78
1.6
1.5
—
—
—
0
0
5
24
2.09
0.74
1.2
1.8
—
—
—
0
0
7
38
1.85
0.73
1.3
1.7
—
—
—
0
0
52
426
1.24
0.73
2.7
2.5
46.95
33.21
u/l
0.50
44
357
41
327
1.27
0.72
5.1
2.9
128.95
128.79
g/l
0.02
41
315
5
26
1.93
0.70
3.0
1.3
131.60
85.11
ng/l
—
5
26
5
26
1.93
0.70
1.8
2.8
—
—
—
0
0
23
170
1.36
0.68
2.0
1.9
—
—
—
0
0
17
119
1.44
0.67
5.4
3.1
1.00
2.02
index
—
6
58
7
43
1.63
0.67
1.1
1.3
—
—
—
0
0
20
146
1.38
0.64
1.8
1.2
—
—
—
0
0
15
104
1.45
0.62
1.9
1.3
—
—
—
0
0
5
30
1.67
0.61
2.4
2.4
13.54
13.24
%
—
5
30
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
182
1679
1.11
0.59
2.1
1.9
1.34
1.34
mmol/l
0.02
155
1409
24
185
1.31
0.56
2.0
2.0
—
—
—
0
0
23
177
1.31
0.55
1.1
1.1
—
—
—
0
0
9
61
1.48
0.54
1.3
1.6
—
—
—
0
0
9
63
1.43
0.52
1.1
1.8
—
—
—
0
0
19
144
1.33
0.51
1.7
1.6
4.02
9.65
iu/ml
—
5
33
7
45
1.56
0.49
1.3
1.6
—
—
—
0
0
7
46
1.53
0.48
1.3
1.7
—
—
—
0
0
10
68
1.48
0.47
1.4
1.5
—
—
—
0
0
7
48
1.46
0.47
1.9
2.7
1463.29
1330.90
mg
—
7
48
22
174
1.27
0.45
1.4
1.5
0.44
0.35
mg/l
—
8
79
7
51
1.38
0.44
1.4
1.1
—
—
—
0
0
25
306
0.81
0.44
1.6
2.0
—
—
—
0
0
5
31
1.62
0.43
1.0
1.5
14.38
18.08
u/l
—
5
26
12
87
1.38
0.42
1.4
1.5
—
—
—
0
0
5
33
1.52
0.41
1.2
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.4
1.5
72.09
52.88
ug/l
—
5
36
8
111
0.72
0.37
3.1
1.6
—
—
—
0
0
14
107
1.31
0.37
7.0
2.1
75.89
61.12
%
1.91
14
107
9
70
1.29
0.36
1.6
2.6
105.89
105.04
mmol/l
—
9
70
9
70
1.29
0.36
1.6
2.6
1.21
1.19
mmol/l
—
9
70
23
277
0.82
0.36
1.6
1.9
—
—
—
0
0
9
71
1.27
0.36
1.1
1.2
—
—
—
0
0
22
180
1.23
0.36
5.7
3.4
50.68
101.29
u/ml
0.58
22
171
51
573
0.88
0.35
1.4
1.5
—
—
—
0
0
6
42
1.43
0.35
1.0
1.0
—
—
—
0
0
58
520
1.13
0.34
3.4
4.4
6.95
21.68
ug/l
0.87
52
439
6
45
1.34
0.34
1.2
1.7
—
—
—
0
0
47
416
1.14
0.33
1.3
1.5
—
—
—
0
0
14
109
1.29
0.33
1.4
1.3
468.50
557.56
mg/l
0.53
14
104
7
100
0.70
0.30
1.0
1.3
—
—
—
0
0
10
76
1.32
0.28
1.4
1.6
—
—
—
0
0
48
531
0.90
0.28
5.1
4.8
32.17
32.01
%
0.03
30
339
13
161
0.80
0.27
1.6
1.3
—
—
—
0
0
8
64
1.25
0.27
3.3
3.9
124.88
17.99
u/ml
—
8
64
13
106
1.23
0.23
2.5
1.5
14731.50
18278.12
e6/l
—
8
73
12
97
1.24
0.23
1.4
1.2
—
—
—
0
0
5
40
1.25
0.22
1.0
1.9
—
—
—
0
0
48
440
1.10
0.21
2.5
2.3
12.01
13.21
nmol/l
0.47
41
391
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
8
105
0.76
0.21
1.1
1.1
1.44
1.51
g/l
—
8
105
5
43
1.16
0.21
1.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
13
153
0.85
0.18
2.1
1.8
50.00
39.90
nmol/l
0.63
13
147
12
142
0.84
0.17
1.8
2.1
—
—
—
0
0
10
120
0.83
0.17
2.6
1.8
179.70
226.48
pmol/l
—
10
113
8
69
1.16
0.16
1.3
1.4
—
—
—
0
0
9
78
1.15
0.15
1.6
1.5
—
—
—
0
0
14
122
1.15
0.13
2.4
2.2
11.06
12.23
mg/l
0.17
14
115
9
109
0.82
0.13
1.3
1.1
0.84
0.88
g/l
—
9
109
9
109
0.82
0.13
1.0
1.1
—
15.36
—
0
11
55
523
1.06
0.11
9.7
7.5
—
—
—
0
0
11
96
1.15
0.10
2.0
3.5
4.56
28.56
mg/l
—
5
76
6
55
1.09
0.09
1.0
1.5
—
—
—
0
0
6
55
1.09
0.09
1.0
1.5
—
—
—
0
0
6
55
1.09
0.09
1.0
1.5
—
—
—
0
0
6
57
1.05
0.08
2.5
1.2
224.00
257.80
pmol/l
—
6
50
6
57
1.05
0.08
1.0
1.5
—
—
—
0
0
7
68
1.03
0.08
1.3
1.3
—
—
—
0
0
11
122
0.90
0.07
1.7
2.0
—
—
—
0
0
12
131
0.91
0.06
1.7
1.7
—
—
—
0
0
11
101
1.09
0.04
1.5
1.3
—
—
—
0
0
11
101
1.09
0.04
1.5
1.3
—
—
—
0
0
69
677
1.02
0.03
1.3
1.3
26.98
38.78
iu/ml
0.73
18
200
11
111
0.99
0.00
1.4
1.1
—
—
—
0
0
11
111
0.99
0.00
1.4
1.1
—
—
—
0
0
10
105
0.95
0.00
3.5
2.5
965.84
81.90
ug/min
—
5
64
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
97.83
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
69
1.01
-0.00
1.3
1.3
—
133.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
56
0.89
-0.00
1.2
1.6
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_APHAKIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_APHAKIA | 1.166 [1.01, 1.34] | 0.033 |
| Birth year | 0.994 [0.99, 1.0] | 0.218 |
During the follow-up period (1.1.1998 — 31.12.2019), 474 out of 1272 females with H7_APHAKIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_APHAKIA | 1.201 [1.03, 1.4] | 0.021 |
| Birth year | 0.985 [0.97, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 1466 males with H7_APHAKIA died.
Mortality risk
Mortality risk for people of age
years, who have H7_APHAKIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.206% |
| 5 | 0.591% | 1.283% |
| 10 | 1.564% | 3.269% |
| 15 | 2.999% | 6.2% |
| 20 | 5.598% | 10.411% |
Relationships between endpoints
↥Index endpoint: H7_APHAKIA – Aphakia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data