auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1463 |
4. Check minimum number of eventsNone |
1463 |
5. Include endpointsNone |
1463 |
6. Filter based on genotype QC (FinnGen only) |
1328 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Disorder of external ear, unspecified
based on the number of shared cases.
Similar with more cases:
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7369 | 3573 | 3766 |
| Only index persons | 7023 | 3453 | 3570 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | 0.11 |
| Only index persons | 0.13 | 0.13 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 57.40 | 57.69 | 57.22 |
| Only index persons | 57.52 | 57.75 | 57.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1328 | 706 | 622 |
| Unadjusted period prevalence (%) | 0.27 | 0.25 | 0.29 |
| Median age at first event (years) | 59.32 | 57.08 | 61.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1369
- Matched controls
- 13690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.9
ICD-10 Finland
Otitis externa, unspecified
13.6
307.7
399
402
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
2326.0
307.7
1032
18
A46
ICD-10 Finland
Erysipelas
10.0
307.7
671
1197
H60.3
ICD-10 Finland
Other infective otitis externa
27.3
226.8
158
65
H60.8
ICD-10 Finland
Other otitis externa
17.9
212.5
179
114
H60.1
ICD-10 Finland
Cellulitis of external ear
29.3
174.7
118
44
H62.0
ICD-10 Finland
Otitis externa in bacterial diseases classified elsewhere
621.9
170.1
165
*
H60
ICD-10 Finland
Otitis externa
7.3
124.0
198
310
H62.1*B02.8
ICD-10 Finland
Otitis externa in zoster
+∞
102.4
97
*
H01
ICPC
Ear pain/earache
4.1
89.3
288
829
H70
ICPC
Otitis externa
10.2
82.4
95
99
S76
ICPC
Skin infection other
5.3
81.5
178
374
H29
ICPC
Ear symptom/complaint other
3.7
75.2
287
921
J01DB01
ATC
cefalexin; oral
5.4
63.9
1277
9878
J01CE08
ATC
benzathine benzylpenicillin; parenteral
12.9
57.5
56
45
H04
ICPC
Ear discharge
5.7
55.3
107
200
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
9.2
53.5
66
75
D07AB02
ATC
hydrocortisone butyrate; topical
2.4
48.5
510
2741
UDC00
NOMESCO Finland
Ear microscopy
3.7
46.3
162
483
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
+∞
42.9
41
*
H62.2
ICD-10 Finland
Otitis externa in mycoses
430.5
42.4
42
*
J01FF01
ATC
clindamycin; systemic
2.3
41.9
467
2541
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
14.1
40.0
37
27
H62.2*B37.2
ICD-10 Finland
Otitis externa in candidiasis
398.5
39.3
39
*
H66.9
ICD-10 Finland
Otitis media, unspecified
3.7
38.8
130
375
D07AC01
ATC
betamethasone; topical
2.1
37.7
576
3516
B02.8
ICD-10 Finland
Zoster with other complications
12.6
37.6
37
30
H62.2*B36.9
ICD-10 Finland
Otomycosis NOS
190.0
35.9
37
*
H61.2
ICD-10 Finland
Impacted cerumen
3.6
35.9
126
375
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.3
35.6
142
459
D07XC01
ATC
betamethasone; topical
2.7
35.1
223
933
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.6
34.4
239
1044
H62.1*B00.19
ICD-10 Finland
Otitis externa in herpesviral [herpes simplex] infection
+∞
30.3
29
*
S02CA02
ATC
flumetasone and antiinfectives; otic
3.4
28.9
107
329
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
28.7
710
4974
L03.2
ICD-10 Finland
Cellulitis of face
9.6
27.1
32
34
S29
ICPC
Skin symptom/complaint other
2.1
26.6
321
1756
J01DA01
ATC
[U] cefalexin
1.9
26.5
880
6698
E0000UV, ,
ATC
1.8
25.4
604
4128
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
25.1
328
1843
G51.0
ICD-10 Finland
Bell palsy
4.4
25.0
63
147
SPAT1255
SPAT
Intravenous administration of medicine
2.8
23.0
122
462
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
4.4
22.7
58
137
TDA90
NOMESCO Finland
Removal wax from ear
6.6
22.3
36
56
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.4
21.4
157
697
D07AA02
ATC
hydrocortisone; topical
2.1
21.1
214
1087
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.6
21.1
71
205
J01CE02
ATC
phenoxymethylpenicillin; oral
1.8
20.6
951
7683
J05AB11
ATC
valaciclovir; oral
2.1
20.5
234
1243
H60.0
ICD-10 Finland
Abscess of external ear
25.9
20.5
28
11
H61.0
ICD-10 Finland
Perichondritis of external ear
202.8
19.6
20
*
J01MA02
ATC
ciprofloxacin; systemic
1.7
19.6
539
3766
D07AC13
ATC
mometasone; topical
1.8
19.3
415
2703
J01CF05
ATC
flucloxacillin; systemic
2.4
18.8
132
573
D11AH01
ATC
tacrolimus; topical
7.8
18.7
26
34
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
18.6
330
2026
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
4.5
18.6
46
106
H92.0
ICD-10 Finland
Otalgia
2.7
18.6
103
399
H13
ICPC
Plugged feeling ear
1.9
18.3
278
1626
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.9
17.8
249
1415
H81
ICPC
Excessive ear wax
1.9
17.6
251
1436
D07CC01
ATC
betamethasone and antibiotics; topical
2.1
17.4
194
1018
D07AB08
ATC
desonide; topical
2.2
17.4
164
808
Z3231
NOMESCO Finland
Registered nurse
1.7
17.3
376
2445
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.0
17.2
77
265
H65.0
ICD-10 Finland
Acute serous otitis media
4.9
17.1
38
80
R50.9
ICD-10 Finland
Fever, unspecified
1.9
17.1
227
1267
D07BC01
ATC
betamethasone and antiseptics; topical
2.1
16.9
179
922
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.0
16.8
202
1088
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
16.5
721
5588
N02BE01
ATC
paracetamol; systemic, rectal
2.2
16.5
1232
11044
D07AD01
ATC
clobetasol; topical
1.9
16.4
242
1398
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
16.1
122
548
SPAT1263
SPAT
Sampling
1.6
16.0
557
4077
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
15.9
15.7
25
16
E000001, ,
ATC
1.8
15.6
265
1597
Z71.8
ICD-10 Finland
Other specified counselling
1.6
15.6
471
3324
D05AX52
ATC
calcipotriol, combinations; topical
2.7
15.3
86
335
D05AX02
ATC
calcipotriol; topical
3.1
15.2
65
218
AA1AD
NOMESCO Finland
CT of head and brain
1.7
15.1
399
2717
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.0
14.8
186
1016
S01
ICPC
Pain/tenderness of skin
2.7
14.7
79
301
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
4.9
14.5
32
67
DC1AD
NOMESCO Finland
Temporalbone CT
6.5
14.1
23
36
D06AX01
ATC
fusidic acid; topical
2.1
14.0
137
683
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
13.9
485
3523
H62.4*L01.0
ICD-10 Finland
Otitis externa in impetigo
+∞
13.6
13
*
DFF00
NOMESCO Finland
Pure tone audiometry
2.0
13.5
148
770
R60.0
ICD-10 Finland
Localized oedema
1.9
13.4
175
968
H02AB06
ATC
prednisolone; systemic
1.5
13.1
632
4917
H71
ICD-10 Finland
Cholesteatoma of middle ear
6.0
13.1
23
39
H61.8
ICD-10 Finland
Other specified disorders of external ear
11.1
13.0
24
22
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
13.0
242
1494
R06AE07
ATC
cetirizine; oral
1.5
12.8
571
4363
L20.0
ICD-10 Finland
Besnier prurigo
2.2
12.7
105
489
Z2221
NOMESCO Finland
Medical doctor
1.6
12.7
356
2445
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
12.5
168
936
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
12.5
187
1079
S06
ICPC
Rash localized
2.5
12.5
82
345
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.3
12.5
32
76
J01CA04
ATC
amoxicillin; systemic
1.7
12.4
1094
9661
N03AX09
ATC
lamotrigine; oral
2.5
12.3
77
317
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
12.3
182
1048
B02.9
ICD-10 Finland
Zoster without complication
2.2
12.2
104
490
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.7
11.9
38
106
T90
ICPC
Diabetes non-insulin dependent
1.6
11.7
329
2255
G47.3
ICD-10 Finland
Sleep apnoea
1.6
11.7
331
2274
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
11.6
175
1012
L21.0
ICD-10 Finland
Seborrhoea capitis
4.9
11.5
25
52
Z3226
NOMESCO Finland
Physiotherapist
1.7
11.4
235
1489
R42
ICD-10 Finland
Dizziness and giddiness
1.6
11.3
304
2059
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.9
11.1
53
190
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
11.1
162
927
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
11.1
296
2002
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
11.0
96
457
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
10.9
325
2254
T82
ICPC
Obesity
2.5
10.9
68
280
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
10.8
100
488
S18
ICPC
Laceration/cut
1.5
10.8
620
4933
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.7
10.7
216
1357
A04
ICPC
Weakness/tiredness general
1.7
10.7
204
1262
H02AB07
ATC
prednisone; oral
1.8
10.5
175
1043
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.5
10.5
36
106
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
10.4
258
1710
E000003, ,
ATC
2.6
10.4
62
250
S70
ICPC
Herpes zoster
2.9
10.2
47
165
M79.6
ICD-10 Finland
Pain in limb
1.5
10.2
582
4610
L73.2
ICD-10 Finland
Hidradenitis suppurativa
4.4
10.1
25
58
H65.2
ICD-10 Finland
Chronic serous otitis media
4.5
10.0
24
54
R02
ICPC
Shortness of breath/dyspnoea
1.7
10.0
177
1072
N02AX02
ATC
tramadol; systemic, rectal
1.5
10.0
566
4470
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
3.9
10.0
29
76
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
3.9
10.0
29
76
E66.8
ICD-10 Finland
Other obesity
2.2
9.9
83
389
J01DA09
ATC
[U] cefadroxil
1.5
9.9
341
2436
SPAT1254
SPAT
Administration of medicine
1.7
9.9
179
1091
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
4.3
9.9
25
59
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
9.8
322
2275
H60.4
ICD-10 Finland
Cholesteatoma of external ear
26.2
9.8
13
5
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
4.0
9.8
27
68
J02AC01
ATC
fluconazole; systemic
1.5
9.8
477
3657
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
9.8
784
6596
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
9.7
148
857
N05AA02
ATC
levomepromazine; systemic
2.5
9.7
62
258
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
9.7
508
3949
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.7
9.7
52
199
L17
ICPC
Foot/toe symptom/complaint
1.5
9.7
395
2924
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
9.6
137
777
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
9.6
218
1412
L04AA01
ATC
[U] ciclosporin
4.5
9.6
23
52
J01DA06
ATC
[U] cefuroxime
1.7
9.5
184
1143
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
9.5
480
3702
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
9.4
93
466
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
21.9
9.4
13
6
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.7
9.3
50
191
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
4.9
9.3
20
41
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.1
9.3
39
130
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
9.3
574
4588
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.3
9.3
70
314
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
9.3
460
3530
P01AB01
ATC
metronidazole; oral, rectal
1.4
9.3
510
3991
L40.9
ICD-10 Finland
Psoriasis, unspecified
3.6
9.3
30
85
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.2
307
2174
C03CA01
ATC
furosemide; systemic
1.5
9.2
351
2557
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.6
9.1
52
205
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
9.1
944
8271
L04AD01
ATC
ciclosporin; systemic
3.5
9.1
31
91
ZXA10
NOMESCO Finland
Bilateral
1.6
9.1
227
1505
L21
ICD-10 Finland
Seborrhoeic dermatitis
3.3
9.1
33
101
J05AB01
ATC
aciclovir; systemic
1.5
9.1
281
1958
A10BA02
ATC
metformin; oral
1.5
9.1
367
2706
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.2
9.0
72
332
N06AX12
ATC
bupropion; oral
2.0
9.0
99
516
J01MA12
ATC
levofloxacin; systemic
1.6
9.0
236
1584
SPAT1260
SPAT
Consultation of another employee
1.6
8.9
214
1403
R74
ICPC
Upper respiratory infection acute
1.5
8.9
414
3132
E66.01
ICD-10 Finland
Obesity due to excess calories
1.8
8.9
133
765
R03AC02
ATC
salbutamol; inhalant
1.4
8.9
708
5905
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
8.9
162
990
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
8.8
164
1006
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
8.8
76
362
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
8.7
120
673
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.3
8.7
63
278
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
8.7
166
1026
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
8.6
146
872
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.3
8.6
65
292
R60.9
ICD-10 Finland
Oedema, unspecified
2.1
8.6
77
371
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
8.5
215
1428
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.5
8.5
53
219
A03
ICPC
Fever
1.6
8.4
218
1456
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
3.5
8.4
28
81
J01FA06
ATC
roxithromycin; oral
1.4
8.4
492
3879
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
8.4
336
2467
N05AF03
ATC
chlorprothixene; systemic
2.9
8.4
38
133
J01AA02
ATC
doxycycline; systemic
1.5
8.4
1015
9073
TQW80
NOMESCO Finland
Local dermatologic skincare
2.9
8.3
39
139
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
8.3
119
677
F29
ICPC
Eye symptom/complaint other
1.8
8.3
138
822
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
8.2
103
561
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
3.6
8.1
26
73
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
8.1
78
387
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.8
8.1
40
147
SPAT1310
SPAT
Counselling related to known health issue
1.4
8.1
381
2884
Z2446
NOMESCO Finland
Social worker
2.0
8.0
88
458
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
6.3
8.0
20
32
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
8.0
76
375
H71
ICPC
Acute otitis media/myringitis
4.2
8.0
21
51
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.0
7.9
33
110
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
7.9
302
2193
D05AX03
ATC
calcitriol; topical
4.0
7.9
22
56
R4110
NOMESCO Finland
Physiotherapy
1.5
7.9
345
2572
R5120
NOMESCO Finland
Preparation of an aid
2.6
7.8
44
173
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.1
7.8
32
106
A02BC02
ATC
pantoprazole; systemic
1.4
7.7
889
7806
E000002, ,
ATC
1.8
7.7
126
745
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
7.7
113
647
L30.3
ICD-10 Finland
Infective dermatitis
2.4
7.7
51
217
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.7
361
2727
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
7.6
85
445
D05BB02
ATC
acitretin; oral
2.8
7.6
36
129
N05AH02
ATC
clozapine; systemic
3.1
7.6
31
102
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.5
634
5284
D02AE01
ATC
carbamide; topical
2.0
7.5
81
420
A02BC01
ATC
omeprazole; systemic
1.5
7.5
325
2418
SPAT1301
SPAT
No procedures
1.4
7.5
368
2802
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
7.5
186
1230
D01AC02
ATC
miconazole; topical
1.9
7.5
99
550
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.4
168
1084
E66.00
ICD-10 Finland
Metabolic syndrome
2.0
7.4
82
428
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
7.4
89
478
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.8
7.4
117
685
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.4
522
4225
C09CA01
ATC
losartan; oral
1.4
7.4
322
2396
S97
ICPC
Chronic ulcer skin
1.9
7.4
85
451
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.3
323
2407
H620, A499,
ICD-10 Finland
+∞
7.3
7
*
H62.1
ICD-10 Finland
Otitis externa in viral diseases classified elsewhere
+∞
7.3
7
*
RD210, ,
NOMESCO Finland
3.3
7.3
26
79
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
7.2
106
607
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
4.5
7.2
17
38
D09AB01
ATC
zinc bandage without supplements; topical
3.2
7.2
28
90
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.2
7.2
59
276
N06AB04
ATC
citalopram; systemic
1.5
7.1
242
1714
N03AX16
ATC
[U] pregabalin
1.5
7.0
284
2082
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.9
7.0
20
52
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.4
7.0
45
189
SPAT1234
SPAT
Support of social functional capacity
2.1
7.0
62
299
SPAT1241
SPAT
Extensive assessment of psychosocial situation
4.4
7.0
17
39
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
6.9
244
1742
A98
ICPC
Health maint/preventive medicine
2.1
6.9
1313
12577
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
6.9
111
655
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
6.9
125
763
K10.3
ICD-10 Finland
Alveolitis of jaws
2.0
6.8
67
336
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
6.8
180
1207
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.7
6.8
21
58
ZY010
NOMESCO Finland
Hospital outpatient
2.0
6.8
67
337
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.7
233
1654
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.7
370
2863
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.1
6.7
64
317
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
6.7
147
942
R06AX27
ATC
desloratadine; oral
1.4
6.7
349
2677
L04AC16
ATC
guselkumab; systemic
22.6
6.7
9
*
N06AX16
ATC
venlafaxine; oral
1.6
6.6
180
1214
R06.0
ICD-10 Finland
Dyspnoea
1.4
6.6
336
2565
ZXE00
NOMESCO Finland
One hour or less
1.4
6.6
465
3747
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.9
6.6
78
418
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
6.6
56
266
E000007, ,
ATC
2.0
6.6
66
334
EBA10
NOMESCO Finland
Operative extraction of tooth
1.6
6.5
153
996
H61.9
ICD-10 Finland
Disorder of external ear, unspecified
10.1
6.5
12
12
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
10.1
6.5
12
12
G53.0*B02.20
ICD-10 Finland
Trigeminal neuralgia after shingles
10.1
6.5
12
12
H02AB04
ATC
methylprednisolone; systemic
1.6
6.5
170
1135
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
2.7
6.5
34
129
C07AB07
ATC
bisoprolol; oral
1.3
6.5
587
4910
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
6.2
6.5
16
26
E000006, ,
ATC
1.9
6.5
80
435
D50.8
ICD-10 Finland
Other iron deficiency anaemias
3.5
6.4
21
60
J01FA09
ATC
clarithromycin; systemic
1.4
6.4
380
2974
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
2.9
6.4
29
102
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
6.4
86
481
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
6.6
6.3
15
23
N05BA04
ATC
oxazepam; oral
1.4
6.3
315
2393
N05AH04
ATC
quetiapine; oral
1.5
6.3
218
1546
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.3
361
2809
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.2
6.3
52
244
U71
ICPC
Cystitis/urinary infection other
1.9
6.3
79
432
N05AX12
ATC
aripiprazole; systemic
2.2
6.2
52
245
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
1.9
6.2
73
390
K08.3
ICD-10 Finland
Retained dental root
1.7
6.2
104
620
N02BF02
ATC
pregabalin; oral
1.8
6.2
89
507
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.2
230
1655
L40.8
ICD-10 Finland
Other psoriasis
5.1
6.2
18
36
J01FA10
ATC
azithromycin; systemic
1.3
6.2
708
6114
N05AN01
ATC
lithium; oral
2.6
6.1
34
133
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
6.1
109
661
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
6.1
30
110
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
6.1
70
371
M04AA01
ATC
allopurinol; systemic
1.6
6.1
150
988
N05AH03
ATC
olanzapine; systemic
1.8
6.1
83
466
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.3
6.1
45
202
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
6.0
304
2312
H70.1
ICD-10 Finland
Chronic mastoiditis
10.1
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1316
11691
4.25
27.38
24.5
16.0
26.04
24.13
mg/l
1.57
1228
9639
905
7024
1.85
24.73
13.5
9.7
4.19
4.11
e9/l
0.61
793
6151
913
7157
1.83
23.55
5.7
5.4
6.79
6.69
mmol/l
0.84
878
6810
706
5284
1.69
19.94
2.4
2.1
94.15
95.37
pmol/l
0.28
415
2870
1095
9286
1.90
19.59
10.2
8.4
80.41
78.14
u/l
0.45
1041
8860
1313
11982
3.34
19.26
26.9
18.7
139.66
139.67
mmol/l
0.05
1292
11757
1314
12007
3.35
19.02
27.2
18.9
3.98
3.98
mmol/l
0.04
1291
11765
715
5430
1.66
18.61
7.6
6.9
1.21
1.21
mmol/l
0.47
668
5059
706
5434
1.62
16.71
6.6
5.2
35.47
35.75
g/l
0.62
671
5129
770
6081
1.61
16.16
9.2
7.6
1.21
1.21
mmol/l
0.59
672
5279
321
2036
1.75
15.94
2.2
1.9
—
—
—
0
0
34
70
4.96
15.73
1.1
1.2
—
—
—
0
0
1220
10953
2.05
15.36
6.1
5.3
2.20
1.89
mu/l
0.54
1132
10210
324
2100
1.71
14.75
3.2
2.9
1.11
1.00
e6/l
0.25
174
1102
429
3006
1.62
14.39
2.8
2.4
—
—
—
0
0
928
7775
1.60
14.29
5.6
4.6
1506.83
1762.82
e6/l
—
6
117
433
3065
1.60
13.82
4.8
4.1
88.80
90.38
%
0.68
424
3007
400
2778
1.62
13.81
1.7
1.7
0.93
1.20
mg/l
2.29
318
2135
565
4257
1.56
13.74
4.0
3.5
7.71
7.72
mmol/l
0.03
489
3649
1332
12503
3.42
13.71
29.7
20.6
80.92
77.52
umol/l
2.43
1321
12366
205
1207
1.82
12.88
4.6
3.6
1.46
1.91
mmol/l
0.98
181
1033
1025
8887
1.61
12.79
5.2
4.3
13.57
11.74
mm/h
3.67
967
8354
1241
11364
1.98
12.41
21.5
15.2
81.21
81.99
ml/min/173m2
0.62
1170
10551
1057
9259
1.62
12.36
4.9
4.4
14.51
14.77
pmol/l
3.07
981
8577
435
3153
1.56
12.24
2.7
2.3
2.91
2.86
mg/l
0.16
381
2706
535
4079
1.51
11.82
4.4
4.2
8.24
8.76
mg/mmol
0.13
361
2596
792
6543
1.50
11.81
7.5
6.8
11.99
11.55
umol/l
0.19
765
6264
581
4507
1.50
11.81
4.6
4.0
73.20
102.82
e6/l
0.52
419
3165
304
2049
1.62
11.57
3.2
2.6
13.00
13.34
umol/l
0.32
278
1914
464
3454
1.52
11.39
1.8
1.7
18.95
20.13
nmol/l
0.90
391
2963
550
4243
1.50
11.36
3.8
3.6
2.36
2.35
mmol/l
1.13
502
3891
1223
11205
1.86
11.34
7.6
6.3
40.46
39.15
mmol/mol
4.56
1129
10566
42
131
3.28
11.15
1.2
1.2
—
—
—
0
0
189
1136
1.77
11.01
6.9
8.1
1.33
1.33
mmol/l
0.01
183
1116
694
5635
1.47
10.93
19.6
14.8
1.26
1.24
inr
0.47
591
4698
125
660
1.98
10.91
1.4
1.5
—
—
—
0
0
287
1933
1.61
10.89
3.3
3.1
2.93
2.38
e6/l
0.29
137
938
455
3399
1.51
10.87
3.7
3.2
0.54
0.43
e6/l
0.35
347
2472
594
4691
1.47
10.72
4.7
3.8
30.34
52.49
ng/l
1.03
437
3270
230
1471
1.68
10.69
2.1
1.8
—
—
—
0
0
156
893
1.84
10.67
1.9
1.7
—
—
—
0
0
283
1909
1.61
10.65
3.2
2.6
2.41
2.30
g/l
2.09
255
1772
1317
12434
2.56
10.63
15.9
12.1
27.79
26.62
u/l
1.54
1282
12120
263
1751
1.62
10.42
3.3
2.6
21.79
23.36
%
1.16
243
1643
238
1547
1.65
10.38
2.0
1.8
—
—
—
0
0
1342
12806
3.43
10.32
36.4
24.2
249.51
250.29
e9/l
0.16
1324
12567
1342
12811
3.41
10.21
36.3
24.1
91.07
91.12
fl
0.18
1335
12677
1342
12812
3.41
10.19
36.8
24.7
40.41
40.90
%
0.71
1335
12670
1342
12812
3.41
10.19
36.3
24.2
4.48
4.51
e12/l
1.15
1320
12540
1342
12814
3.40
10.15
36.4
24.2
6.98
6.72
e9/l
5.48
1320
12535
1342
12817
3.39
10.08
36.7
24.4
134.69
136.01
g/l
2.70
1335
12682
492
3798
1.46
9.74
2.4
2.2
171.74
232.19
u/l
1.13
472
3617
224
1458
1.64
9.67
6.6
8.8
0.69
0.98
mmol/l
0.59
187
1203
226
1475
1.64
9.66
6.7
8.8
11.67
12.18
kpa
0.98
217
1430
226
1475
1.64
9.66
6.7
8.8
5.13
5.11
kpa
0.10
216
1427
209
1339
1.66
9.60
10.0
7.1
—
—
—
0
0
279
1929
1.56
9.34
1.9
2.1
29.23
29.48
s
0.31
271
1878
506
3954
1.44
9.28
3.9
3.4
150.23
71.84
e6/l
0.50
398
3002
130
734
1.85
9.28
1.9
1.6
—
—
—
0
0
206
1330
1.65
9.16
6.8
9.2
95.80
95.70
%
0.13
199
1288
278
1933
1.55
9.05
1.8
1.7
1232.09
1195.87
nmol/l
0.24
203
1495
181
1134
1.69
9.03
8.8
7.7
10.83
9.70
mmol/l
1.23
176
1091
862
7434
1.43
9.02
3.3
3.0
—
—
—
0
0
765
6481
1.41
8.71
4.5
3.9
0.00
2.20
estimate
0.80
146
1381
427
3280
1.44
8.41
3.4
2.7
363.95
344.95
umol/l
2.73
376
2919
462
3601
1.43
8.40
3.3
3.2
1478.58
1256.13
ng/l
0.56
391
3103
128
750
1.78
8.10
8.2
10.9
24.24
24.30
mmol/l
0.08
122
741
655
5447
1.39
8.08
2.8
2.5
74.03
76.61
nmol/l
1.63
607
4966
685
5740
1.39
8.06
3.1
2.8
—
—
estimate
—
0
0
753
6410
1.39
8.05
4.5
3.8
0.00
0.00
estimate
0.50
141
1360
1268
11947
1.83
7.97
6.4
5.7
2.63
2.73
mmol/l
3.11
1183
11191
532
4281
1.40
7.95
3.5
3.3
33.35
32.65
u/l
0.16
492
4049
162
1028
1.65
7.67
2.5
2.4
7.86
7.52
ug/l
0.07
146
934
761
6520
1.38
7.65
4.6
3.9
0.00
0.25
estimate
0.54
134
1291
158
997
1.66
7.65
2.7
2.8
10.00
10.80
g/l
1.97
147
925
360
2723
1.44
7.58
3.0
2.7
6.56
5.56
e6/l
0.36
336
2489
943
8389
1.40
7.41
4.2
3.4
51.31
49.45
u/l
0.27
887
7939
291
2127
1.47
7.32
4.0
3.4
0.80
0.82
mmol/l
2.10
278
2026
128
774
1.72
7.26
1.2
1.3
32.20
53.06
au/ml
—
9
62
617
5143
1.36
7.22
2.1
1.9
1.51
1.38
mmol/l
2.86
523
4365
321
2400
1.44
7.15
3.3
3.0
2.46
2.45
mmol/l
1.78
288
2178
1218
11409
1.61
7.08
6.1
5.1
6.14
5.94
mmol/l
4.65
1122
10562
1250
11790
1.69
7.00
5.6
5.1
4.47
4.64
mmol/l
7.16
1169
11096
314
2348
1.44
6.97
4.3
3.8
894.70
429.45
ng/l
0.49
242
1793
136
847
1.67
6.92
2.4
2.5
10.69
20.34
au/ml
1.96
13
89
34
125
2.76
6.89
3.9
3.6
—
—
—
0
0
493
3990
1.37
6.86
3.0
2.7
63.72
62.13
u/l
0.09
468
3724
671
5714
1.34
6.62
3.7
3.1
124.65
131.19
ug/l
0.33
619
5365
49
221
2.26
6.51
1.4
1.3
—
—
—
0
0
49
221
2.26
6.51
1.4
1.3
—
—
—
0
0
1243
11744
1.63
6.45
5.5
5.0
1.36
1.45
mmol/l
13.08
1159
10984
1195
11203
1.52
6.26
4.7
4.3
1.42
1.30
mmol/l
5.34
1098
10403
61
308
2.03
6.11
3.3
3.3
1.59
1.70
index
0.06
32
172
140
910
1.60
6.02
3.3
3.0
218.82
195.99
ng/l
0.22
130
834
230
1665
1.46
6.00
8.1
6.1
1.06
1.03
mmol/l
1.16
223
1560
34
136
2.54
5.89
2.0
1.7
25.50
33.44
ng/l
0.41
34
136
176
1212
1.52
5.87
2.8
2.2
369.82
378.71
nmol/l
0.27
167
1135
172
1184
1.52
5.75
2.7
2.5
31.69
83.97
u/l
0.69
147
998
321
2491
1.38
5.62
1.5
1.5
2.53
2.46
g/l
0.25
195
1605
199
1429
1.46
5.40
4.6
4.6
247.29
249.64
u/l
0.07
189
1361
72
403
1.83
5.36
2.2
1.8
—
—
—
0
0
279
2135
1.39
5.30
1.6
1.5
—
—
—
0
0
13
22
5.96
5.22
1.2
1.0
—
—
—
0
0
76
440
1.77
5.08
2.5
2.0
—
—
—
0
0
150
1031
1.51
5.05
2.6
3.0
65.92
66.72
g/l
0.59
133
959
33
141
2.37
5.02
1.1
1.1
—
—
—
0
0
21
71
2.99
5.00
1.1
1.1
—
—
—
0
0
354
2837
1.33
4.96
1.4
1.3
2.10
1.62
u/ml
0.25
96
806
72
425
1.73
4.53
2.7
2.7
9.23
10.45
g/l
2.13
61
389
135
930
1.50
4.51
1.6
1.4
—
—
—
0
0
193
1430
1.41
4.40
2.5
2.8
11.17
7.99
umol/l
0.47
170
1274
76
462
1.68
4.31
2.3
2.2
463.78
440.46
ug/l
0.04
71
439
316
2539
1.32
4.28
1.7
1.7
44867341.90
33380710.99
pmol/l
0.14
263
2130
353
2881
1.30
4.27
5.0
4.0
1.02
1.54
kg/l
0.50
215
1925
85
540
1.61
4.08
1.8
1.9
6.69
1.81
ug/l
0.84
72
488
59
340
1.77
4.06
1.3
1.2
—
—
—
0
0
78
488
1.63
3.98
2.7
2.6
3.82
3.75
g/l
0.10
69
455
10
18
5.59
3.97
1.1
1.3
—
—
—
0
0
78
489
1.63
3.95
2.7
2.6
4.23
4.22
g/l
0.01
69
455
78
489
1.63
3.95
2.7
2.6
7.42
7.35
g/l
0.15
69
455
71
435
1.67
3.93
5.4
3.9
24.86
24.89
mmol/l
0.03
63
410
58
336
1.76
3.93
1.7
1.4
—
—
—
0
0
58
338
1.75
3.85
1.3
1.2
—
—
—
0
0
74
463
1.63
3.79
2.8
2.7
2.92
2.94
g/l
0.06
65
429
118
821
1.48
3.78
5.1
3.6
5.29
5.13
kpa
1.19
112
798
83
535
1.59
3.77
1.4
1.8
4.75
7.24
iu/ml
0.61
17
126
12
29
4.17
3.70
1.0
1.1
—
—
—
0
0
69
427
1.65
3.70
1.5
1.7
—
—
—
0
0
65
399
1.66
3.60
1.6
1.5
0.25
0.09
iu/ml
0.63
16
61
12
30
4.03
3.60
1.7
2.3
16.40
17.85
umol/l
0.25
12
30
69
432
1.63
3.54
2.0
2.9
1.06
1.18
g/l
0.10
58
380
55
324
1.73
3.54
2.0
1.6
9727.89
12041.40
e6/l
0.29
36
234
121
863
1.44
3.43
1.4
1.3
640.24
217.28
u/ml
1.54
112
806
101
696
1.49
3.42
5.1
3.5
1.70
1.80
mmol/l
0.11
80
521
12
32
3.77
3.39
1.1
1.2
—
—
—
0
0
57
347
1.67
3.28
1.4
1.8
—
—
—
0
0
137
1009
1.40
3.26
2.2
2.7
66.47
67.04
ml/min/173m2
0.06
58
428
143
1062
1.39
3.24
2.9
3.0
68.72
70.19
e9/l
0.23
107
795
27
130
2.10
3.19
1.1
1.6
—
—
—
0
0
287
2361
1.27
3.18
1.3
1.3
24.65
33.27
iu/ml
0.77
65
713
556
4919
1.22
3.18
4.5
3.8
0.02
0.03
estimate
0.41
118
1145
24
111
2.18
3.13
2.7
2.8
—
—
—
0
0
18
73
2.49
3.13
2.2
2.3
514.15
580.31
e6/l
0.14
13
62
12
35
3.45
3.11
1.2
1.2
—
—
—
0
0
126
923
1.40
3.10
5.1
4.0
110.16
88.30
ng/l
1.21
115
822
137
1020
1.38
3.07
2.7
2.6
0.54
0.42
e6/l
0.26
128
969
415
3578
1.23
3.03
4.8
4.0
0.00
0.01
estimate
1.34
132
1269
58
363
1.62
3.02
1.5
1.3
—
—
—
0
0
15
57
2.65
2.97
1.0
3.4
42.80
105.20
umol/l
—
5
30
8
17
4.73
2.92
1.1
1.4
—
—
—
0
0
155
1189
1.34
2.88
2.5
2.3
0.21
0.22
g/l
0.15
143
1111
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
71
2.41
2.80
1.1
1.1
—
—
—
0
0
47
286
1.67
2.75
4.6
3.2
39.49
33.48
umol/l
0.90
41
258
11
34
3.25
2.73
1.2
1.1
—
—
—
0
0
15
60
2.52
2.70
1.2
2.1
—
—
—
0
0
6
10
6.02
2.70
1.0
1.2
—
—
—
0
0
26
133
1.97
2.66
1.4
1.3
—
—
—
0
0
56
360
1.58
2.65
2.0
1.3
11.36
10.02
u/l
0.30
49
292
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
59
384
1.56
2.65
3.7
2.7
0.26
0.36
iu/ml
2.81
31
204
25
127
1.99
2.61
1.5
1.3
13307.75
115557.60
e6/l
1.13
16
87
26
135
1.94
2.56
1.8
1.6
372.67
351.79
mu/l
0.12
21
110
16
68
2.37
2.56
1.3
1.4
—
82.22
—
0
9
55
356
1.57
2.54
1.3
1.2
8.51
7.72
u/ml
—
8
53
58
382
1.54
2.49
1.6
1.5
252.89
272.20
ug/g
0.27
35
224
57
374
1.55
2.49
3.5
3.7
4.66
3.14
ratio
0.36
37
215
47
296
1.61
2.44
1.2
1.2
51.15
54.83
u/ml
0.05
11
30
159
1258
1.30
2.40
4.7
3.3
—
—
—
0
0
78
552
1.44
2.38
2.0
2.0
1.71
1.54
g/l
0.72
67
491
21
104
2.04
2.37
1.1
1.1
104.62
107.09
pmol/l
0.10
21
104
260
2187
1.23
2.35
1.3
1.3
4.76
10.85
u/ml
1.61
84
862
15
65
2.32
2.32
6.1
1.8
—
—
—
0
0
18
85
2.13
2.29
1.4
1.5
—
—
—
0
0
45
286
1.59
2.27
1.2
1.3
8.16
40.79
e6/l
0.85
32
216
12
47
2.57
2.27
1.1
1.3
4.72
4.72
umol/l
0.00
12
40
176
1422
1.27
2.27
5.3
4.8
31.39
31.86
%
0.24
117
967
23
120
1.93
2.26
1.1
1.1
—
—
—
0
0
7
18
3.90
2.25
1.1
1.3
—
—
—
0
0
15
66
2.29
2.25
1.4
2.8
1256.20
1196.03
u/ml
0.03
15
66
65
450
1.47
2.24
1.5
1.6
55.00
13.24
u/ml
—
8
108
195
1602
1.25
2.19
2.2
1.9
1.52
1.49
%
0.17
179
1393
61
419
1.48
2.19
3.8
3.9
36.06
41.57
mg/l
0.19
55
355
61
420
1.47
2.16
3.8
3.9
62.41
62.05
mg/l
0.01
56
355
43
274
1.59
2.16
8.1
6.1
244.40
383.68
iu/ml
—
10
37
10
36
2.79
2.14
1.2
1.2
—
—
—
0
0
45
291
1.56
2.13
1.3
1.4
155.18
411.39
e6/l
0.46
34
228
54
366
1.49
2.08
1.8
2.7
0.00
0.00
g/l
-0.00
49
318
55
375
1.49
2.06
1.7
2.7
0.01
0.01
g/l
0.01
50
337
9
32
2.82
2.00
1.2
1.1
—
—
—
0
0
9
32
2.82
2.00
1.2
1.1
—
—
—
0
0
461
4145
1.17
1.99
5.2
5.3
3.13
2.50
ug/l
0.32
412
3767
21
112
1.89
1.96
1.1
1.0
—
—
—
0
0
79
584
1.37
1.93
2.0
1.7
0.33
0.34
mg/l
0.04
37
289
7
22
3.19
1.88
1.0
1.1
110.86
101.00
%
—
7
22
56
392
1.45
1.86
1.5
1.3
—
—
—
0
0
40
261
1.55
1.85
1.2
1.3
175.24
250.67
u/ml
1.34
24
158
71
520
1.39
1.84
1.2
1.2
0.30
1.11
u/ml
—
6
38
60
427
1.42
1.83
1.7
1.6
333.56
297.88
mu/l
0.29
55
394
190
1590
1.23
1.82
3.0
2.4
137.26
120.77
ug/g
0.24
161
1287
7
23
3.05
1.80
1.1
1.2
—
—
—
0
0
11
47
2.35
1.78
1.0
1.0
—
—
—
0
0
53
372
1.44
1.75
1.5
1.4
—
—
—
0
0
9
36
2.51
1.74
1.2
1.4
—
—
—
0
0
43
291
1.49
1.71
1.6
1.6
—
—
—
0
0
23
133
1.74
1.70
2.0
1.8
—
—
—
0
0
16
82
1.96
1.70
1.3
1.7
—
—
—
0
0
80
607
1.34
1.69
1.1
1.0
—
—
—
0
0
24
144
1.68
1.58
2.0
1.8
—
—
—
0
0
35
233
1.52
1.53
2.0
1.8
—
—
—
0
0
96
761
1.28
1.50
2.7
3.5
4.47
4.54
pmol/l
0.35
90
681
59
440
1.36
1.43
2.5
2.6
—
—
—
0
0
17
98
1.74
1.31
4.0
3.7
15.08
12.28
index
1.03
12
64
16
92
1.75
1.25
1.0
1.1
—
—
—
0
0
6
25
2.41
1.24
1.2
1.2
—
—
—
0
0
13
70
1.87
1.24
1.8
1.3
11.05
29.40
umol/l
4.15
13
63
24
155
1.56
1.23
1.2
1.3
0.20
0.18
nmol/l
0.40
19
121
100
819
1.24
1.23
1.3
1.2
147.09
139.68
u/ml
0.08
38
333
71
560
1.28
1.20
2.0
2.1
38.59
39.38
u/l
0.14
63
506
13
71
1.84
1.19
1.6
2.2
—
—
—
0
0
12
64
1.88
1.18
4.4
4.2
0.58
0.89
index
1.04
12
64
37
265
1.41
1.17
1.3
1.4
—
13.18
—
0
5
11
57
1.94
1.17
1.9
1.7
—
—
—
0
0
11
57
1.94
1.17
1.9
1.7
—
—
—
0
0
15
87
1.73
1.15
1.1
1.3
—
—
—
0
0
15
87
1.73
1.15
1.1
1.3
—
—
—
0
0
12
65
1.85
1.13
1.1
1.1
2659.33
1539.66
miu/ml
2.29
12
65
34
242
1.42
1.12
1.4
1.4
162.00
160.30
au/ml
—
9
71
11
58
1.90
1.12
1.1
1.1
—
77.43
%
—
0
7
29
201
1.45
1.10
1.6
1.5
0.32
0.32
nmol/l
0.01
20
158
69
550
1.27
1.09
2.1
1.9
—
—
—
0
0
49
374
1.32
1.07
1.8
2.2
196.57
190.72
%
0.21
49
359
40
296
1.36
1.07
1.4
1.5
—
—
—
0
0
36
262
1.38
1.06
1.8
1.6
—
—
—
0
0
5
22
2.28
1.03
1.2
1.3
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
23.36
33.75
mg/l
—
5
17
11
60
1.84
1.03
2.3
2.5
—
—
—
0
0
9
48
1.88
1.00
1.4
1.0
—
—
—
0
0
19
123
1.55
1.00
1.5
1.5
—
—
—
0
0
49
379
1.30
0.99
2.5
2.2
16521.75
3989.92
u/l
0.47
12
156
131
1129
1.18
0.99
2.8
2.4
11.84
13.38
nmol/l
1.33
116
1036
27
190
1.43
0.97
1.1
1.3
—
—
—
0
0
24
165
1.46
0.97
1.1
1.1
—
—
—
0
0
361
3336
1.11
0.97
4.3
4.4
21.67
21.25
%
0.20
165
1554
9
50
1.81
0.96
2.8
2.0
—
—
—
0
0
9
50
1.81
0.96
2.8
2.0
—
—
—
0
0
9
50
1.81
0.96
2.8
2.0
—
—
—
0
0
18
117
1.55
0.94
2.1
1.7
—
—
—
0
0
18
117
1.55
0.94
2.1
1.7
—
—
—
0
0
18
117
1.55
0.94
2.1
1.7
—
—
—
0
0
75
617
1.23
0.93
1.7
1.4
29.74
28.65
iu/l
0.10
63
527
55
437
1.27
0.92
2.3
1.9
40.78
39.58
nmol/l
0.09
50
425
41
313
1.32
0.92
1.2
1.1
4.00
3.82
—
7
45
13
78
1.67
0.91
1.2
1.3
5.92
5.95
ug/l
0.01
13
66
80
665
1.22
0.91
2.3
2.0
—
—
—
0
0
87
1032
0.83
0.91
1.7
1.8
3.64
3.47
mmol/l
0.66
62
742
34
253
1.35
0.90
1.4
1.5
—
—
—
0
0
8
42
1.91
0.88
2.4
1.5
—
—
—
0
0
8
42
1.91
0.88
1.5
1.4
—
—
—
0
0
14
87
1.62
0.87
1.1
1.0
680.56
688.81
ng/l
—
9
58
26
187
1.40
0.85
1.2
1.3
—
0.43
—
0
14
44
344
1.29
0.85
1.3
1.3
—
—
—
0
0
17
112
1.52
0.85
1.4
1.2
—
—
—
0
0
122
1393
0.86
0.82
2.0
2.0
3.63
3.51
ratio
0.53
102
1101
50
400
1.26
0.82
2.2
2.0
96.00
93.02
%
0.38
50
391
15
97
1.55
0.81
1.2
1.1
—
—
—
0
0
15
97
1.55
0.81
1.2
1.1
—
—
—
0
0
18
258
0.69
0.79
1.9
3.6
20.64
26.50
mg/l
0.43
12
176
34
260
1.32
0.78
1.4
1.4
—
—
—
0
0
17
115
1.48
0.77
1.2
1.3
413052.86
83407.16
e6/l
—
7
63
31
235
1.33
0.76
5.3
3.4
12.04
8.72
pmol/l
0.77
31
235
15
99
1.52
0.75
1.7
2.2
1.56
1.67
u/field
—
9
58
18
124
1.46
0.75
1.3
2.1
7.63
5.55
umol/l
0.21
11
88
44
351
1.26
0.75
1.9
1.7
—
—
—
0
0
12
75
1.61
0.75
1.2
1.2
—
—
—
0
0
5
24
2.09
0.74
1.0
1.3
—
87.83
—
0
6
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
5
24
2.09
0.74
1.0
1.3
—
73.67
—
0
6
43
343
1.26
0.74
1.9
1.6
—
—
—
0
0
14
92
1.53
0.72
1.2
1.1
—
—
—
0
0
5
27
1.85
0.68
2.2
1.6
0.46
0.42
e9/l
—
5
27
14
94
1.49
0.67
1.2
1.1
—
—
—
0
0
15
103
1.46
0.65
1.2
1.1
—
—
—
0
0
22
163
1.36
0.64
1.9
1.7
—
—
—
0
0
16
112
1.43
0.63
1.1
1.2
—
—
—
0
0
35
279
1.26
0.62
1.5
2.3
0.87
0.86
nmol/l
0.03
30
240
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
191.80
308.72
pmol/l
—
5
18
37
298
1.25
0.61
2.6
2.2
133.81
129.62
g/l
0.56
27
243
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
22
167
1.32
0.57
2.0
2.6
31.64
32.66
pg
0.47
22
167
6
38
1.58
0.54
2.0
1.4
8.62
9.08
ug/l
—
6
38
138
1256
1.11
0.53
2.2
2.0
—
—
—
0
0
17
125
1.36
0.53
1.2
1.3
55.32
53.72
u/l
0.05
17
113
11
74
1.49
0.53
1.1
1.3
12.55
13.81
u/l
0.26
11
69
10
66
1.52
0.52
2.7
1.9
—
—
—
0
0
10
66
1.52
0.52
2.7
1.9
—
—
—
0
0
10
66
1.52
0.52
2.7
1.9
—
—
—
0
0
6
40
1.50
0.51
1.2
1.1
—
—
—
0
0
11
75
1.47
0.50
2.5
1.6
118.27
99.29
ng/l
0.28
11
75
11
75
1.47
0.50
1.1
1.2
0.54
0.52
ratio
—
6
43
6
41
1.47
0.50
1.2
1.3
—
—
—
0
0
23
180
1.28
0.49
1.2
1.3
0.64
10.57
nmol/l
0.50
23
171
14
101
1.39
0.49
2.1
1.6
0.48
1.13
promille
—
9
84
7
45
1.56
0.49
2.0
1.7
42.43
41.15
g/l
—
7
45
163
1760
0.92
0.47
1.7
1.5
—
—
—
0
0
18
137
1.32
0.47
2.7
2.3
12.00
19.89
mg/l
—
7
54
15
199
0.75
0.46
1.9
1.6
—
—
—
0
0
44
375
1.18
0.45
1.6
1.5
—
—
—
0
0
43
502
0.85
0.45
1.2
1.1
1.49
1.53
g/l
0.50
43
502
0
15
0.00
0.41
0.0
1.1
—
72.00
—
0
15
0
15
0.00
0.41
0.0
1.0
—
0.10
—
0
9
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
263
2498
1.07
0.40
3.2
3.2
0.77
0.75
ug/l
0.08
179
1556
0
18
0.00
0.40
0.0
1.1
—
28.33
—
0
10
125
1154
1.09
0.39
2.1
1.9
—
—
—
0
0
10
71
1.41
0.39
2.1
1.4
—
—
—
0
0
10
71
1.41
0.39
2.1
1.4
—
—
—
0
0
68
609
1.12
0.38
1.5
1.3
—
—
—
0
0
9
66
1.37
0.38
2.9
1.9
—
—
—
0
0
31
261
1.19
0.38
1.5
1.5
—
—
—
0
0
5
36
1.39
0.38
1.2
1.3
—
—
—
0
0
14
181
0.77
0.38
1.1
1.0
—
—
—
0
0
9
68
1.33
0.37
1.2
1.2
26.33
19.40
u/l
—
9
57
9
68
1.33
0.37
1.0
1.1
—
—
—
0
0
37
318
1.17
0.37
1.4
1.2
—
—
—
0
0
17
134
1.27
0.37
1.2
1.3
756.45
1721.80
e6/l
2.06
11
90
9
70
1.29
0.36
1.2
1.2
106.11
78.85
u/l
—
9
60
24
288
0.83
0.35
1.5
1.5
—
—
—
0
0
6
42
1.43
0.35
2.3
1.2
93.50
109.94
%
—
6
35
46
520
0.88
0.34
1.3
1.2
0.88
0.90
g/l
0.21
46
520
15
118
1.27
0.33
1.2
1.2
—
—
—
0
0
21
173
1.22
0.33
1.7
1.6
—
—
—
0
0
369
3563
1.05
0.32
3.7
3.3
0.03
0.04
estimate
0.19
116
1087
10
74
1.35
0.32
2.1
1.8
—
—
—
0
0
26
220
1.19
0.32
1.2
1.1
7.53
18.77
au/ml
—
7
60
7
100
0.70
0.30
1.9
1.4
—
—
—
0
0
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
8
109
0.73
0.29
2.4
3.9
18.81
51.09
u/ml
—
8
109
7
57
1.23
0.29
2.6
1.4
—
—
—
0
0
7
57
1.23
0.29
2.6
1.4
—
—
—
0
0
14
112
1.25
0.28
1.6
1.5
—
—
—
0
0
8
63
1.27
0.27
1.4
1.3
165.50
472.03
u/l
—
8
58
13
161
0.81
0.27
1.1
1.0
0.35
0.31
u/ml
—
7
54
9
74
1.22
0.25
1.3
1.6
5.33
6.40
u/l
—
9
62
104
979
1.07
0.24
6.2
3.9
1.23
1.23
mmol/l
0.31
90
844
35
391
0.89
0.24
1.5
1.5
—
—
—
0
0
5
38
1.32
0.23
1.6
1.7
65.80
100.47
nmol/24h
—
5
38
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
772.90
—
0
10
8
101
0.79
0.21
2.5
1.5
17.63
13.12
umol/l
—
8
96
5
43
1.16
0.21
4.0
2.7
0.59
0.61
mmol/l
—
5
43
0
14
0.00
0.20
0.0
1.4
—
14.50
—
0
14
20
174
1.15
0.19
1.1
1.1
17.63
4.85
u/ml
0.95
11
72
23
203
1.14
0.19
1.1
1.1
2.22
1.75
u/ml
0.17
15
99
6
52
1.15
0.19
1.3
1.3
—
—
—
0
0
19
217
0.87
0.18
1.2
1.0
7.82
4.58
u/ml
0.37
13
112
10
83
1.21
0.15
1.3
1.5
122.72
161.04
pmol/l
—
10
83
9
80
1.13
0.15
1.6
1.6
—
—
—
0
0
27
247
1.09
0.13
1.3
1.1
4.33
2.27
u/ml
0.32
20
133
22
199
1.11
0.13
1.3
1.2
1.80
5.82
u/ml
1.64
15
82
15
132
1.14
0.13
2.8
2.5
1.18
1.20
mmol/l
1.54
15
132
43
404
1.07
0.12
1.2
1.3
344.91
233.31
miu/ml
0.79
14
190
16
178
0.90
0.11
1.8
1.8
—
—
—
0
0
12
105
1.14
0.11
2.0
1.7
—
—
—
0
0
13
146
0.89
0.10
1.3
1.5
60.46
55.86
ug/l
0.10
13
146
39
413
0.94
0.10
1.5
1.6
781.97
987.92
mu/l
1.10
28
340
17
154
1.11
0.10
2.2
1.5
—
—
—
0
0
17
155
1.10
0.09
2.2
1.5
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
15
136
1.10
0.08
2.8
2.5
105.73
105.68
mmol/l
0.02
15
136
15
136
1.10
0.08
2.8
2.5
4.03
4.07
mmol/l
0.18
15
136
6
57
1.05
0.08
1.2
1.1
—
—
—
0
0
5
60
0.83
0.08
1.0
1.8
—
0.66
—
0
12
8
74
1.08
0.07
1.3
1.1
—
—
—
0
0
8
76
1.05
0.07
1.4
1.6
4.81
6.22
u/l
—
8
60
16
147
1.09
0.07
2.3
1.5
—
—
—
0
0
16
147
1.09
0.07
2.3
1.5
—
—
—
0
0
9
84
1.07
0.07
1.6
1.6
—
—
—
0
0
35
334
1.05
0.06
1.9
1.9
12.24
20.80
iu/l
0.19
13
139
16
148
1.08
0.06
2.3
1.5
—
—
—
0
0
18
192
0.94
0.05
1.1
1.0
17.86
2.82
u/ml
—
10
97
10
90
1.11
0.05
1.6
1.4
78.90
78.48
umol/l
—
10
90
47
482
0.97
0.03
3.5
3.5
489.28
2888.64
u/ml
0.60
40
415
124
1255
0.99
0.03
3.8
4.5
5.31
22.76
ug/l
1.70
93
1038
25
241
1.04
0.02
1.5
1.6
51.11
61.34
ug/l
0.48
15
200
28
289
0.97
0.02
2.6
2.4
141.69
123.99
ug/min
0.11
19
179
46
469
0.98
0.02
1.7
1.8
8.74
3.88
mg/l
0.65
38
345
22
227
0.97
0.01
1.5
1.5
1.01
0.98
ratio
—
8
146
22
227
0.97
0.01
1.5
1.5
0.73
1.15
ratio
—
8
146
22
227
0.97
0.01
1.5
1.5
0.73
1.17
ratio
—
9
146
58
576
1.01
0.00
4.6
3.5
1.02
1.02
ratio
0.21
49
537
22
218
1.01
0.00
1.5
1.5
—
—
—
0
0
14
141
0.99
0.00
1.1
1.3
7.25
7.33
mmol/l
—
8
122
22
225
0.98
0.00
1.5
1.5
—
—
—
0
0
20
205
0.98
0.00
1.3
1.2
2.10
3.69
u/ml
—
10
64
19
195
0.97
0.00
1.2
1.1
—
—
—
0
0
20
205
0.98
0.00
1.5
1.6
—
—
—
0
0
11
105
1.05
0.00
1.5
1.2
—
—
—
0
0
16
155
1.03
0.00
2.3
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1745.20
—
0
5
0
6
0.00
0.00
0.0
1.0
—
0.01
—
0
6
5
59
0.85
0.00
7.6
2.9
1.10
1.25
%
—
5
59
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
2.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.1
—
19.83
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
7.70
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
2.88
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.6
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXTDISINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXTDISINOTH | 1.404 [1.19, 1.66] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.619 |
During the follow-up period (1.1.1998 — 31.12.2019), 419 out of 2954 females with H8_EXTDISINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXTDISINOTH | 1.515 [1.27, 1.8] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 517 out of 3092 males with H8_EXTDISINOTH died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXTDISINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.167% | 0.355% |
| 5 | 0.973% | 1.728% |
| 10 | 2.414% | 4.346% |
| 15 | 4.32% | 8.045% |
| 20 | 7.788% | 13.438% |
Relationships between endpoints
↥Index endpoint: H8_EXTDISINOTH – Disorder of external ear, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data