Chondrosarcoma

C3_CHONDROSARCOMA

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519870
1. Apply sex-specific rule None	519870
2. Check conditions None	519870
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Cause of death: ICD-10 — C40.2\|C4104\|C4106\|C4114\|C4122\|C4132\|C4142\|C4182\|C4192 Cancer registry: Topography ICD-O-3 — ANY Cancer registry: Morphology ICD-O-3 — 9220\|9230\|9231 Cancer registry: Behaviour codes — 3 2 out of 7 registries used, show all original rules.	113
4. Check minimum number of events None	113
5. Include endpoints None	113
6. Filter based on genotype QC (FinnGen only)	111

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze: DF8

NAME	C3_CHONDROSARCOMA
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C40.2\|C4104\|C4106\|C4114\|C4122\|C4132\|C4142\|C4182\|C4192
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	ANY
CANC_TOPO_EXCL
CANC_MORPH	9220\|9230\|9231
CANC_MORPH_EXCL
CANC_BEHAV	3

Similar endpoints

↥

List of similar endpoints to Chondrosarcoma based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	111	50	61
Unadjusted period prevalence (%)	0.02	0.02	0.03
Median age at first event (years)	56.23	54.63	57.55

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
113: Matched controls
1130

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D48.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage

130.2

35.1

C40.22

ICD-10 Finland

Chondrosarcoma of the long bones of the lower extremity

+∞

30.6

9220/3-C40.2

ICD-O-3

Chondrosarcoma, NOS, of long bones of lower limb and associated joints

+∞

28.3

130

Kela drug reimbursment

Malignant tumour

+∞

22.7

WX408

NOMESCO Finland

General anesthesy, balanced

6.4

21.6

151

C41.32

ICD-10 Finland

Chondrosarcoma of the ribs, sternum and clavicle

+∞

18.2

C40.20

ICD-10 Finland

Malignant tumor of the long bones of the lower extremity without histology

+∞

18.2

9220/3-C41.3

ICD-O-3

Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints

+∞

17.1

C40.02

ICD-10 Finland

Chondrosarcoma of the scapula and long bones of the upper extremity

+∞

14.9

GAE06

NOMESCO Finland

Excision of lesion of chest wall

+∞

13.8

H02AB02

ATC

dexamethasone; systemic

57.1

13.2

C41.82

ICD-10 Finland

Overall chondrosarcoma in bone and articular cartilage

+∞

12.7

XX3DW

NOMESCO Finland

Time consuming IT work

13.4

12.7

D16.2

ICD-10 Finland

Benign neoplasm: Long bones of lower limb

72.7

11.9

9220/3-C41.4

ICD-O-3

Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints

+∞

11.7

NFR30

NOMESCO Finland

Extended excision of soft tissue tumour of hip or thigh

+∞

11.7

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

9.8

11.0

C41.42

ICD-10 Finland

Chondrosarcoma of the pelvic bones, sacrum and coccyx

+∞

10.6

9220/3-C40.0

ICD-O-3

Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints

+∞

10.6

GD1BD

NOMESCO Finland

Thorax extensive CT-examination

11.8

10.5

WX402

NOMESCO Finland

General anaesthesia

4.1

10.5

125

ZXE30

NOMESCO Finland

More than five and less than seven hours

19.0

10.2

B01AB05

ATC

enoxaparin; parenteral

3.6

9.9

212

EN1BD

NOMESCO Finland

Very extensive CT examination of mouth and soft tissues of neck

60.3

9.8

B01AB10

ATC

tinzaparin; parenteral

5.7

9.7

L03AA13

ATC

pegfilgrastim; parenteral

108.8

9.6

WF049

NOMESCO Finland

Radiotherapy of metastasis

+∞

9.5

C32.3

ICD-10 Finland

Malignant neoplasm: Laryngeal cartilage

+∞

9.5

NK6BN

NOMESCO Finland

Bone dynamic isotope examination

+∞

9.5

WX302

NOMESCO Finland

Thoracal epidural anesthesy

15.5

9.5

NE1CG

NOMESCO Finland

Pelvic, hip and femur extensive MRI examination with high intensity magnet

26.6

9.1

GD1AA

NOMESCO Finland

Thorax X-ray examination

3.4

9.0

378

R4110

NOMESCO Finland

Physiotherapy

3.3

8.6

199

WF002

NOMESCO Finland

Radical radiotherapy

97.0

8.5

JN4BD

NOMESCO Finland

Extensive body CT

7.9

8.5

ZXE20

NOMESCO Finland

More than three and less than five hours

4.1

8.4

9220/3-C41.0

ICD-O-3

Chondrosarcoma, NOS, of bones of skull and face and associated joints

+∞

8.4

NK6CT

NOMESCO Finland

Bone biopsy with CT guidance

+∞

8.4

GAE23

NOMESCO Finland

Resection of chest wall and prosthetic repair

+∞

8.4

C41.3

ICD-10 Finland

Malignant neoplasm: Ribs, sternum and clavicle

+∞

8.4

C41.06

ICD-10 Finland

Chondrosarcoma of the skull or facial bones except maxilla

+∞

8.4

ZXE10

NOMESCO Finland

More than one and less than three hours

3.1

8.1

234

JN4AD

NOMESCO Finland

Body CT examination

7.2

7.6

A03FA01

ATC

metoclopramide; systemic, rectal

3.9

7.5

D38.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Larynx

85.5

7.5

A04AA02

ATC

granisetron; systemic, transdermal

85.5

7.5

ZXB10

NOMESCO Finland

Medial

85.5

7.5

QAE10

NOMESCO Finland

Excision of other lesion extending through all layers of skin in head or neck

17.2

7.4

C78.0

ICD-10 Finland

Secondary malignant neoplasm of lung

+∞

7.4

WF004

NOMESCO Finland

Palliative radiotherapy

+∞

7.4

115

Kela drug reimbursment

Breast cancer

+∞

7.4

DQB20

NOMESCO Finland

Partial excision of larynx

+∞

7.4

C40.2

ICD-10 Finland

Malignant neoplasm: Long bones of lower limb

+∞

7.4

WF003

NOMESCO Finland

Adjuvant radiotherapy

+∞

7.4

C79.8

ICD-10 Finland

Secondary malignant neoplasm of other specified sites

+∞

7.4

NER30

NOMESCO Finland

Extended excision of soft tissue tumour of pelvis

+∞

7.4

9220/3-C32.3

ICD-O-3

Chondrosarcoma, NOS, of laryngeal cartilage

+∞

7.4

C41.22

ICD-10 Finland

Chondrosarcoma of the spine

+∞

7.4

PJA12

NOMESCO Finland

Sentinel node biopsy

+∞

7.4

TPH07

NOMESCO Finland

Cathetrisation of artery

4.0

7.3

WX404

NOMESCO Finland

Intravenous generell anesthesy

3.5

7.3

111

GBB00

NOMESCO Finland

Tracheostomy

21.7

7.3

ZXE40

NOMESCO Finland

More than seven and less than nine hours

42.7

6.8

ZXD10

NOMESCO Finland

Scheduled procedure

2.8

6.7

278

C61

ICD-10 Finland

Malignant neoplasm of prostate

73.8

6.5

NFB60

NOMESCO Finland

Demanding prosthetic replacement of hip

73.8

6.5

ZX012

NOMESCO Finland

Radiotherapy with large shaped fields - isocentric therapy

73.8

6.5

NGR20

NOMESCO Finland

Intralesional or marginal excision of tumor of knee or lower leg

73.8

6.5

QA1S1

NOMESCO Finland

Photography of skin or subcutaneous tissue in head

73.8

6.5

NF3AA

NOMESCO Finland

Femur X-ray examination

8.5

6.3

17071

ICD-8 Finland

Malignant neoplasm of bone, Lower limb, long bones

+∞

6.3

WD125

NOMESCO Finland

Demanding cystostatic therapy of methastized malignancy

+∞

6.3

C40.00

ICD-10 Finland

Malignant tumor of the scapula and the long bones of the upper extremity without histology

+∞

6.3

8500/3-C50.9

ICD-O-3

Infiltrating duct carcinoma, NOS, of breast, NOS

+∞

6.3

DQD50

NOMESCO Finland

Endoscopic insertion of stent in larynx

+∞

6.3

8090/3-C44.9

ICD-O-3

Basal cell carcinoma, NOS, of skin, NOS

+∞

6.3

NBR20

NOMESCO Finland

Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm

+∞

6.3

WZC30

NOMESCO Finland

Teaching

3.4

6.2

NG4AA

NOMESCO Finland

Lower leg X-ray examination

10.9

6.2

TimeCodeWAS

↥

TODO / Current known limitations:

Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
Legend / how to read the glyphs.
Proper column names.
Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
Download CSV not working.
No filters and sorters.
Limited amount of endpoints with TimeCodeWAS data.
Cross-links to Risteys lab test pages for lab test codes.

OMOP Concept

ln(OR) -5y

ln(OR) -1y

ln(OR) -1m

ln(OR) d0

ln(OR) +1m

ln(OR) +1y

ln(OR) +5y

MCC -5y

MCC -1y

MCC -1m

MCC d0

MCC +1m

MCC +1y

MCC +5y

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
D48.0 (45586112)

Chondrosarcoma of the long bones of the lower extremity
C40.22 (2000500655)

Physiotherapy
R4110 (2001310233)

General anesthesia, balanced
WX408 (2001310808)

Medical Oncology
90 (38004507)

Chondrosarcoma of the ribs, sternum and clavicle
C41.32 (2000500699)

Body height measure
50373000 (4177340)

Body mass index
60621009 (4245997)

Scheduled procedure
ZXD10 (2001311387)

Blood group antibody screen [Presence] in Serum or Plasma
890-4 (3001079)

Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
9220/3-C41.3 (36526470)

Chondrosarcoma, NOS, of long bones of lower limb and associated joints
9220/3-C40.2 (36548029)

Oncology Clinic/Center
261QX0200X (38004268)

Otolaryngology
4 (38004449)

Orthopedic Surgery
20 (38004465)

Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M
62238-1 (40764999)

Tissue Pathology biopsy report
66121-5 (40768804)

Inpatient Hospital
21 (8717)

Outpatient Hospital
22 (8756)

Inpatient Visit
IP (9201)

Outpatient Visit
OP (9202)

General Surgery
2 (38004447)

Emergency Room Visit
ER (9203)

Sodium [Moles/volume] in Serum or Plasma
2951-2 (3019550)

Potassium [Moles/volume] in Serum or Plasma
2823-3 (3023103)

Creatinine [Moles/volume] in Serum or Plasma
14682-9 (3020564)

C reactive protein [Mass/volume] in Serum or Plasma
1988-5 (3020460)

Erythrocyte [DistWidth] in Red Blood Cells
30385-9 (3002385)

paracetamol; oral, parenteral, rectal
N02BE01 (21604344)

CBC panel - Blood by Automated count
58410-2 (40761511)

Platelets [#/volume] in Blood
26515-7 (3007461)

MCV [Entitic mean volume] in Red Blood Cells
30428-7 (3024731)

MCH [Entitic mass]
28539-5 (3035941)

Leukocytes [#/volume] in Blood
26464-8 (3010813)

Hematocrit [Volume Fraction] of Blood by calculation
20570-8 (3009542)

Hemoglobin [Mass/volume] in Blood
718-7 (3000963)

Erythrocytes [#/volume] in Blood
26453-1 (3026361)

Thorax X-ray examination
GD1AA (2001303617)

MCHC [Entitic Mass/volume] in Red Blood Cells
28540-3 (3003338)

Laboratory Visit
OMOP4822461 (32036)

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768804) Tissue Pathology biopsy report

283

3.91

11.68

2.9

1.6

—

(3044640) Blood type and Crossmatch panel - Blood

285

3.87

11.52

3.8

2.1

—

(4035726) Immunohistochemistry procedure

12.52

11.32

1.2

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

395

3.98

11.07

3.9

2.5

—

estimate

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

216

3.61

10.13

3.8

2.1

—

(3002256) Pathology report gross observation

4.42

8.43

1.3

1.1

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

4.96

8.33

2.3

2.0

1.83

2.95

ug/l

1.90

(3003396) Base excess in Arterial blood by calculation

112

3.29

6.57

8.8

9.0

0.34

1.32

mmol/l

0.97

(3019977) pH of Arterial blood

116

3.16

6.18

8.8

7.40

7.42

0.72

(3013650) Neutrophils [#/volume] in Blood by Automated count

512

2.38

4.53

9.0

6.6

4.87

4.28

e9/l

0.27

436

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

5.03

4.20

2.0

2.5

0.30

0.38

iu/ml

—

(40758558) Short blood count panel - Blood

266

2.23

4.02

5.2

4.6

—

(3013115) Eosinophils [#/volume] in Blood

504

2.18

3.82

5.2

5.7

0.21

0.20

e9/l

0.06

436

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.80

3.60

2.7

3.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

102

2.58

3.59

2.1

1.9

—

(3001604) Monocytes [#/volume] in Blood

485

2.09

3.50

5.3

5.7

0.57

e9/l

0.02

413

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

5.33

3.45

1.4

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

421

2.05

3.43

7.3

6.4

1.20

1.21

mmol/l

0.64

386

(3019198) Lymphocytes [#/volume] in Blood

498

2.07

3.39

5.6

5.7

1.74

1.84

e9/l

0.53

437

(3006315) Basophils [#/volume] in Blood

489

2.06

3.37

5.3

5.7

0.04

e9/l

0.05

416

(42870588) Differential panel, method unspecified - Blood

302

2.02

3.24

4.9

5.7

—

(3023368) Bacteria identified in Blood by Culture

252

2.06

3.22

5.2

4.0

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

6.14

3.07

1.0

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

6.14

3.07

1.0

1.2

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

411

1.91

2.88

4.3

3.9

34.94

35.94

g/l

0.67

392

(3024891) Influenza virus A+B Ag [Presence] in Specimen

4.45

2.73

1.0

1.1

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

474

1.87

2.69

7.1

1.21

mmol/l

0.05

424

(3032080) INR in Blood by Coagulation assay

461

1.83

2.53

15.2

13.3

1.27

inr

0.01

376

(3021589) Normoblasts [#/volume] in Blood

389

1.81

2.44

9.4

10.4

0.00

e9/l

0.49

310

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

6.47

2.39

1.8

1.4

—

(4094501) Cardiovascular stress test using bicycle ergometer

3.51

2.22

1.1

—

(3000991) Gas panel - Venous blood

2.26

2.20

14.4

10.6

—

(3021788) Differential panel - Synovial fluid

3.85

2.19

1.6

1.3

—

(3035933) Granulocytes/Leukocytes in Blood

4.46

2.18

2.5

2.6

69.83

62.24

—

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

2.44

2.18

2.9

1.9

69.00

62.17

ml/min/173m2

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

588

1.75

2.07

6.6

4.8

6.42

6.72

mmol/l

0.77

557

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.11

1.98

4.7

2.1

265.17

235.85

u/l

0.37

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

108

2.04

1.97

1.3

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

119

1.94

1.82

1.5

1.7

—

(3003694) ABO and Rh group [Type] in Blood

234

1.72

1.79

1.4

1.3

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

1.75

0.0

1.0

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

3.97

1.73

2.8

3.2

12.14

12.78

mg/l

—

(3037121) Protein [Mass/volume] in Urine

0.00

1.56

0.0

2.8

—

288.40

—

(3025941) Bacteria identified in Stool by Culture

0.00

1.55

0.0

1.1

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.96

1.52

1.3

2.8

4.40

3.96

g/l

—

(3019060) Gas panel - Arterial blood

2.16

1.50

2.6

5.7

—

(3044941) Cell count panel - Synovial fluid

3.22

1.45

1.8

1.4

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

3.22

1.45

1.2

1.3

—

(40761511) CBC panel - Blood by Automated count

104

955

2.12

1.44

18.8

12.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

153

1.72

1.44

1.7

1.8

—

(3022145) Colonoscopy Study observation

1.86

1.40

1.8

1.4

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.03

1.40

1.7

2.4

0.19

0.21

g/l

0.75

(3018418) pH of Serum or Plasma

276

1.57

1.38

2.2

3.6

7.42

7.39

2.67

183

(3012095) Magnesium [Moles/volume] in Serum or Plasma

147

1.71

1.37

2.0

2.5

0.82

0.83

mmol/l

0.26

141

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

101

918

1.94

1.36

20.6

14.2

31.97

23.73

mg/l

1.63

736

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

860

1.77

1.35

4.9

5.1

2.03

1.92

mu/l

0.36

786

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.86

1.30

1.4

2.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

196

0.51

1.28

1.5

1.4

1.78

2.68

g/l

—

110

(3003458) Phosphate [Moles/volume] in Serum or Plasma

126

1.71

1.25

2.4

6.6

0.98

1.07

mmol/l

0.85

117

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

110

1.76

1.24

1.6

2.3

4.33

5.70

umol/l

1.28

(3042936) Bacteria identified in Isolate by Culture

143

1.67

1.23

2.3

1.7

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

0.00

1.18

0.0

1.4

—

(3031040) Bacteria [#/volume] in Urine by Automated count

613

1.48

1.17

4.7

4.5

—

399.56

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.57

1.16

1.8

1.1

—

(40761536) Microorganisms panel - Urine sediment

1.96

1.12

6.5

2.7

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

139

1.63

1.10

9.6

7.3

103.76

104.24

mmol/l

0.16

139

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

2.01

1.10

2.6

4.2

2.00

2.14

mmol/l

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

886

1.67

1.08

20.2

13.6

83.76

77.84

ml/min/173m2

1.75

816

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.99

0.0

1.2

—

1.56

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.99

0.0

1.2

—

0.79

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.21

0.93

1.7

1.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.13

0.91

2.0

3.9

—

(3022313) Gas panel - Capillary blood

1.88

0.88

3.0

4.6

—

(3024731) MCV [Entitic mean volume] in Red Blood Cells

106

1008

1.83

0.84

32.4

21.6

90.77

91.32

0.49

106

997

(3035941) MCH [Entitic mass]

106

1009

1.82

0.84

32.4

21.6

30.10

30.44

1.17

106

998

(3009542) Hematocrit [Volume Fraction] of Blood by calculation

106

1009

1.82

0.84

33.8

22.2

39.25

40.79

2.87

106

998

(3000494) Fungus identified in Specimen by Culture

124

1.54

0.81

1.6

1.5

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.80

0.0

1.3

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

227

0.66

0.78

1.1

1.3

1.48

1.20

u/ml

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.78

0.0

1.1

—

0.51

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

104

988

1.66

0.76

13.8

10.3

25.49

25.59

u/l

0.02

957

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.13

0.75

1.6

1.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

2.13

0.75

1.2

2.7

91.40

91.00

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.66

0.74

1.2

1.6

—

(3030467) Casts [#/volume] in Urine by Automated count

252

1.38

0.74

2.6

2.9

0.34

0.35

e6/l

0.02

173

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

127

1.50

0.73

4.8

5.2

33.00

32.67

0.06

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

2.04

0.73

1.8

1.4

351.80

425.05

e6/l

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

2.04

0.73

1.8

1.2

353.80

3.35

e6/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.63

0.73

1.4

1.5

—

(3000963) Hemoglobin [Mass/volume] in Blood

106

1010

1.80

0.72

32.8

21.7

130.07

136.65

g/l

4.03

106

998

(3009343) pH of Capillary blood

1.70

0.71

3.2

4.0

7.44

7.43

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

716

1.34

0.70

4.5

15.91

11.55

mm/h

1.04

660

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.61

0.0

1.1

—

0.18

—

(3029937) Albumin [Presence] in Urine by Test strip

279

1.31

0.60

5.7

3.8

0.00

estimate

-0.00

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.55

0.60

1.5

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

133

1.42

0.59

1.4

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.59

0.0

1.3

—

(3035350) Ketones [Presence] in Urine by Test strip

504

1.26

0.56

4.8

4.0

0.00

estimate

-0.00

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

904

0.76

0.55

6.4

6.9

38.20

40.03

mmol/mol

1.02

847

(3030981) Hyaline casts [#/volume] in Urine by Automated count

0.60

0.55

2.2

2.6

0.10

0.31

e6/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

330

1.28

0.55

2.9

3.2

—

(3045414) Leukocytes [Presence] in Urine

1.48

0.52

1.8

2.1

—

0.00

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

510

1.24

0.49

4.7

4.0

0.00

estimate

-0.00

(3017181) Myelocytes/Leukocytes in Blood

1.52

0.49

6.8

4.0

1.40

0.47

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

927

0.77

0.47

4.7

5.6

4.33

4.50

mmol/l

0.82

870

(3037522) Nuclear Ab [Titer] in Serum

128

0.68

0.46

1.4

—

365.56

—

(3045424) Erythrocytes [Presence] in Urine

1.43

0.46

2.0

2.1

—

0.00

estimate

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

104

1.40

0.46

1.3

1.5

—

(3026008) Bacteria identified in Urine by Culture

280

1.25

0.45

3.6

3.3

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

925

0.78

0.44

4.7

5.4

1.48

1.46

mmol/l

0.13

862

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.54

0.42

1.4

1.5

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

1.7

—

4.06

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

1.7

—

1.20

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

1.7

—

105.94

—

(3024980) IgG subclass 4 [Mass/volume] in Serum

0.00

0.41

0.0

3.6

—

1.12

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.41

0.0

1.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

941

0.79

0.40

5.3

6.3

2.40

2.60

mmol/l

1.42

879

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.0

—

1.61

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.40

0.0

1.1

—

(3021601) Nitrite [Presence] in Urine by Test strip

498

1.20

0.40

4.7

3.9

0.00

estimate

-0.00

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.37

0.39

1.5

1.6

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.39

0.0

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.39

0.0

1.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.41

0.38

1.4

1.6

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.43

0.38

1.0

1.4

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

640

0.84

0.38

2.7

3.2

41.62

44.70

u/l

0.23

604

(3002582) Erythrocytes [#/volume] in Urine

306

1.21

0.36

2.7

3.1

29.73

250.76

e6/l

0.51

228

(3019225) pH of Specimen

1.34

0.33

2.3

3.9

7.38

7.34

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

387

1.18

0.32

5.2

3.8

0.00

0.01

estimate

0.49

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

167

1.24

0.31

2.6

2.9

0.54

1.13

e6/l

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

421

0.85

0.29

1.7

2.0

1.14

1.32

mmol/l

1.18

369

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

700

1.17

0.28

4.5

4.0

14.49

14.96

pmol/l

0.75

642

(46235355) HIV 1 and 2 tests - Meaningful Use set

141

1.24

0.28

1.9

1.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

480

1.15

0.27

2.0

2.1

86.77

95.31

pmol/l

0.61

240

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

441

1.15

0.27

2.0

2.6

84.16

76.13

nmol/l

1.31

386

(3004588) Protein electrophoresis panel - Serum or Plasma

1.21

0.27

1.8

1.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.23

0.26

1.7

1.8

—

(3015736) pH of Urine

404

1.15

0.25

4.3

3.6

6.20

6.19

0.02

228

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

1.37

0.24

2.0

1.3

0.00

g/l

—

(3019150) Specific gravity of Urine by Refractometry

240

1.16

0.23

4.7

4.4

1.02

kg/l

0.97

159

(40768797) Stomach Pathology biopsy report

145

0.81

0.22

1.1

1.2

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.23

0.22

1.6

2.0

35.00

46.40

u/l

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.21

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

0.21

0.0

2.0

—

11.90

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.21

0.0

1.5

—

935.36

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(4062490) Immunoglobulin typing, IgG

0.00

0.21

0.0

1.2

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

2.8

—

(3024139) IgG subclass 3 [Mass/volume] in Serum

0.00

0.21

0.0

1.2

—

0.37

—

(3034274) Bile acid [Moles/volume] in Serum --fasting

0.00

0.21

0.0

1.6

—

3.18

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.6

—

(3027135) IgG subclass 1 [Mass/volume] in Serum

0.00

0.21

0.0

1.2

—

5.87

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

2.0

—

(3028192) IgG subclass 2 [Mass/volume] in Serum

0.00

0.21

0.0

1.2

—

2.85

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.21

0.0

1.3

—

7.97

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.21

0.0

1.7

—

48.50

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

310.95

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.21

0.0

1.1

—

27.92

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.5

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

310

1.14

0.21

2.9

2.7

33.21

37.82

u/l

0.24

295

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.0

—

0.49

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.20

0.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.19

0.20

2.5

2.4

—

(3018095) Leukocytes [#/volume] in Urine

341

1.13

0.19

3.2

3.9

11.50

122.94

e6/l

1.96

233

(40760892) CBC W Ordered Manual Differential panel - Blood

196

1.15

0.18

7.9

4.5

—

(3009508) Creatinine [Moles/volume] in Urine

368

0.89

0.18

2.5

3.4

7.62

7.63

mmol/l

0.00

315

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.79

0.16

1.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

883

0.89

0.15

3.9

4.6

1.15

1.26

mmol/l

1.34

820

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.21

0.14

1.7

4.6

342.60

231.83

ng/l

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

327

1.10

0.14

2.7

3.2

1832.28

1406.62

ng/l

0.15

271

(3020682) Albumin/Creatinine [Ratio] in Urine

361

0.92

0.12

3.1

4.2

3.19

9.67

mg/mmol

1.93

231

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

918

0.90

0.11

4.6

5.3

5.75

6.01

mmol/l

2.00

835

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

125

1.14

0.10

5.9

6.5

—

(4024509) Urine culture

1.12

0.10

2.0

1.9

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.83

0.08

1.0

1.3

—

(3000492) Spirometry study

1.08

0.07

1.3

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.04

0.07

1.8

1.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

277

1.06

0.06

4.6

3.5

0.00

estimate

-0.00

(3012516) Albumin [Mass/volume] in Urine

352

0.95

0.05

2.6

3.5

24.68

62.16

mg/l

1.68

232

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

311

0.95

0.04

5.0

3.8

23.67

24.77

0.14

137

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

109

0.91

0.04

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

272

1.04

0.02

2.6

3.3

—

0.33

—

(1761868) Lipid panel - Serum or Plasma

368

0.97

0.02

2.5

3.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

158

1.01

0.00

2.5

3.2

4.80

2.61

e6/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

405

0.98

0.00

4.3

4.0

31.23

41.74

ng/l

0.42

291

(3019309) Folate [Moles/volume] in Red Blood Cells

181

0.99

0.00

1.5

1.7

1438.27

1173.60

nmol/l

0.40

136

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.0

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3022689) Creatine [Moles/volume] in Urine

0.00

0.0

1.8

—

11.18

—

(3024263) Appearance of Synovial fluid

0.00

0.0

1.2

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

30.76

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.4

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.4

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

38.60

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.4

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

1.3

—

0.67

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

-0.00

0.0

1.0

—

153.67

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

2.5

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

1.2

—

14.68

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.3

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

1.1

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.6

—

86.05

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.2

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

80.67

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

97.75

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

540

1.00

-0.00

3.7

2.7

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.5

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.84

-0.00

2.0

1.5

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.92

-0.00

2.7

1.7

319.67

389.10

nmol/l

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

851.83

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(36660697) Celiac disease serology panel - Serum

0.97

-0.00

1.1

1.2

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_CHONDROSARCOMA – Chondrosarcoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Chondrosarcoma

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Chondrosarcoma (C3_CHONDROSARCOMA)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

TimeCodeWAS

LabWAS

Mortality – FinRegistry

Relationships between endpoints