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This is a non-core endpoint: only basic statistics are computed.

Chondrosarcoma

C3_CHONDROSARCOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C40.2|C4104|C4106|C4114|C4122|C4132|C4142|C4182|C4192
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9220|9230|9231
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

116

4. Check minimum number of events

None

116

5. Include endpoints

None

116

6. Filter based on genotype QC (FinnGen only)

111

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 111 50 61
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 56.23 54.63 57.55

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
113
Matched controls
1130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
130.2
35.1
36
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
30.6
28
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
28.3
26
*
130
Kela drug reimbursment
Malignant tumour
+∞
22.7
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.4
21.6
56
151
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
18.2
17
*
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
18.2
17
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
17.1
16
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
14.9
14
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
13.8
13
*
H02AB02
ATC
dexamethasone; systemic
57.1
13.2
15
*
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
12.7
12
*
XX3DW
NOMESCO Finland
Time consuming IT work
13.4
12.7
22
20
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
72.7
11.9
13
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
11.7
11
*
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
11.7
11
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
9.8
11.0
22
27
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.6
10
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
10.6
10
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.8
10.5
19
19
WX402
NOMESCO Finland
General anaesthesia
4.1
10.5
38
125
ZXE30
NOMESCO Finland
More than five and less than seven hours
19.0
10.2
15
9
B01AB05
ATC
enoxaparin; parenteral
3.6
9.9
51
212
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
60.3
9.8
11
*
B01AB10
ATC
tinzaparin; parenteral
5.7
9.7
20
41
L03AA13
ATC
pegfilgrastim; parenteral
108.8
9.6
10
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
+∞
9.5
9
*
C32.3
ICD-10 Finland
Malignant neoplasm: Laryngeal cartilage
+∞
9.5
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
9.5
9
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
15.5
9.5
15
11
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
26.6
9.1
12
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
9.0
71
378
R4110
NOMESCO Finland
Physiotherapy
3.3
8.6
47
199
WF002
NOMESCO Finland
Radical radiotherapy
97.0
8.5
9
*
JN4BD
NOMESCO Finland
Extensive body CT
7.9
8.5
19
28
ZXE20
NOMESCO Finland
More than three and less than five hours
4.1
8.4
27
80
C41.06
ICD-10 Finland
Chondrosarcoma of the skull or facial bones except maxilla
+∞
8.4
8
*
C41.3
ICD-10 Finland
Malignant neoplasm: Ribs, sternum and clavicle
+∞
8.4
8
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
8.4
8
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
8.4
8
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
8.4
8
*
ZXE10
NOMESCO Finland
More than one and less than three hours
3.1
8.1
51
234
JN4AD
NOMESCO Finland
Body CT examination
7.2
7.6
18
29
A03FA01
ATC
metoclopramide; systemic, rectal
3.9
7.5
26
81
ZXB10
NOMESCO Finland
Medial
85.5
7.5
8
*
A04AA02
ATC
granisetron; systemic, transdermal
85.5
7.5
8
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
85.5
7.5
8
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
17.2
7.4
11
7
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
7.4
7
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
7.4
7
*
9220/3-C32.3
ICD-O-3
Chondrosarcoma, NOS, of laryngeal cartilage
+∞
7.4
7
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
7.4
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.4
7
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
7.4
7
*
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
7.4
7
*
DQB20
NOMESCO Finland
Partial excision of larynx
+∞
7.4
7
*
115
Kela drug reimbursment
Breast cancer
+∞
7.4
7
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
7.4
7
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
7.4
7
*
TPH07
NOMESCO Finland
Cathetrisation of artery
4.0
7.3
24
72
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.5
7.3
31
111
GBB00
NOMESCO Finland
Tracheostomy
21.7
7.3
10
5
ZXE40
NOMESCO Finland
More than seven and less than nine hours
42.7
6.8
8
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
6.7
54
278
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
73.8
6.5
7
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
73.8
6.5
7
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
73.8
6.5
7
*
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
73.8
6.5
7
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
73.8
6.5
7
*
NF3AA
NOMESCO Finland
Femur X-ray examination
8.5
6.3
13
17
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
DQD50
NOMESCO Finland
Endoscopic insertion of stent in larynx
+∞
6.3
6
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
6.3
6
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
6.3
6
*
WZC30
NOMESCO Finland
Teaching
3.4
6.2
25
86
NG4AA
NOMESCO Finland
Lower leg X-ray examination
10.9
6.2
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
64
283
3.91
11.68
2.9
1.6
—
—
—
0
0
64
285
3.87
11.52
3.8
2.1
—
—
—
0
0
20
19
12.52
11.32
1.2
1.4
—
—
—
0
0
77
395
3.98
11.07
3.9
2.5
—
—
estimate
—
0
0
24
65
4.42
8.43
1.3
1.1
—
—
—
0
0
20
47
4.96
8.33
2.3
2.0
1.83
2.95
ug/l
1.90
15
35
30
112
3.29
6.57
8.8
9.0
0.34
1.32
mmol/l
0.97
25
93
30
116
3.16
6.18
8.8
8.8
7.40
7.42
ph
0.72
13
68
75
512
2.38
4.53
9.0
6.6
4.87
4.28
e9/l
0.27
67
436
46
266
2.23
4.02
5.2
4.6
—
—
—
0
0
72
504
2.18
3.82
5.2
5.7
0.21
0.20
e9/l
0.06
61
436
23
102
2.58
3.59
2.1
1.9
—
—
—
0
0
69
485
2.09
3.50
5.3
5.7
0.57
0.57
e9/l
0.02
60
413
62
421
2.05
3.43
7.3
6.4
1.20
1.21
mmol/l
0.64
55
386
70
498
2.07
3.39
5.6
5.7
1.74
1.84
e9/l
0.53
61
437
69
489
2.06
3.37
5.3
5.7
0.04
0.04
e9/l
0.05
60
416
48
302
2.02
3.24
4.9
5.7
—
—
—
0
0
42
252
2.06
3.22
5.2
4.0
—
—
—
0
0
59
411
1.91
2.88
4.3
3.9
34.94
35.94
g/l
0.67
54
392
8
19
4.45
2.73
1.0
1.1
—
—
—
0
0
65
474
1.87
2.69
7.1
7.1
1.21
1.21
mmol/l
0.05
55
424
63
461
1.83
2.53
15.2
13.3
1.27
1.27
inr
0.01
49
376
55
389
1.81
2.44
9.4
10.4
0.00
0.00
e9/l
0.49
42
310
8
24
3.51
2.22
1.1
1.1
—
—
—
0
0
17
82
2.26
2.20
14.4
10.6
—
—
—
0
0
7
19
3.85
2.19
1.6
1.3
—
—
—
0
0
6
14
4.46
2.18
2.5
2.6
69.83
62.24
%
—
6
14
74
588
1.75
2.07
6.6
4.8
6.42
6.72
mmol/l
0.77
68
557
35
234
1.72
1.79
1.4
1.3
—
—
—
0
0
5
13
3.97
1.73
2.8
3.2
12.14
12.78
mg/l
—
5
13
0
42
0.00
1.56
0.0
2.8
—
288.40
—
0
15
0
44
0.00
1.55
0.0
1.1
—
—
—
0
0
12
59
2.16
1.50
2.6
5.7
—
—
—
0
0
5
16
3.22
1.45
1.2
1.3
—
—
—
0
0
5
16
3.22
1.45
1.8
1.4
—
—
—
0
0
104
955
2.12
1.44
18.8
12.9
—
—
—
0
0
17
98
1.86
1.40
1.8
1.4
—
—
—
0
0
13
68
2.03
1.40
1.7
2.4
0.19
0.21
g/l
0.75
13
61
38
276
1.57
1.38
2.2
3.6
7.42
7.39
ph
2.67
26
183
23
147
1.71
1.37
2.0
2.5
0.82
0.83
mmol/l
0.26
23
141
101
918
1.94
1.36
20.6
14.2
31.97
23.73
mg/l
1.63
89
736
96
860
1.77
1.35
4.9
5.1
2.03
1.92
mu/l
0.36
84
786
11
196
0.51
1.28
1.5
1.4
1.78
2.68
g/l
—
6
110
20
126
1.71
1.25
2.4
6.6
0.98
1.07
mmol/l
0.85
20
117
18
110
1.76
1.24
1.6
2.3
4.33
5.70
umol/l
1.28
18
99
22
143
1.67
1.23
2.3
1.7
—
—
—
0
0
0
33
0.00
1.18
0.0
1.4
—
—
—
0
0
72
613
1.48
1.17
4.7
4.5
—
399.56
—
0
9
11
59
1.96
1.12
6.5
2.7
—
—
—
0
0
21
139
1.63
1.10
9.6
7.3
103.76
104.24
mmol/l
0.16
21
139
0
29
0.00
0.99
0.0
1.2
—
0.79
—
0
29
0
29
0.00
0.99
0.0
1.2
—
1.56
—
0
29
8
44
1.88
0.88
3.0
4.6
—
—
—
0
0
106
1008
1.83
0.84
32.4
21.6
90.77
91.32
fl
0.49
106
997
106
1009
1.82
0.84
33.8
22.2
39.25
40.79
%
2.87
106
998
106
1009
1.82
0.84
32.4
21.6
30.10
30.44
pg
1.17
106
998
18
124
1.54
0.81
1.6
1.5
—
—
—
0
0
0
25
0.00
0.80
0.0
1.3
—
—
—
0
0
16
227
0.66
0.78
1.1
1.3
1.48
1.20
u/ml
—
5
64
0
27
0.00
0.78
0.0
1.1
—
0.51
—
0
5
104
988
1.66
0.76
13.8
10.3
25.49
25.59
u/l
0.02
99
957
9
56
1.66
0.74
1.2
1.6
—
—
—
0
0
32
252
1.38
0.74
2.6
2.9
0.34
0.35
e6/l
0.02
24
173
5
25
2.04
0.73
1.8
1.2
353.80
3.35
e6/l
—
5
20
5
25
2.04
0.73
1.8
1.4
351.80
425.05
e6/l
—
5
20
106
1010
1.80
0.72
32.8
21.7
130.07
136.65
g/l
4.03
106
998
10
61
1.70
0.71
3.2
4.0
7.44
7.43
ph
—
10
50
34
279
1.31
0.60
5.7
3.8
0.00
0.00
estimate
-0.00
12
87
0
23
0.00
0.59
0.0
1.3
—
—
—
0
0
57
504
1.26
0.56
4.8
4.0
0.00
0.00
estimate
-0.00
12
97
85
904
0.76
0.55
6.4
6.9
38.20
40.03
mmol/mol
1.02
73
847
6
96
0.60
0.55
2.2
2.6
0.10
0.31
e6/l
—
6
90
12
84
1.48
0.52
1.8
2.1
—
0.00
estimate
—
0
22
57
510
1.24
0.49
4.7
4.0
0.00
0.00
estimate
-0.00
11
87
10
68
1.52
0.49
6.8
4.0
1.40
0.47
%
—
5
15
88
927
0.77
0.47
4.7
5.6
4.33
4.50
mmol/l
0.82
76
870
9
128
0.68
0.46
1.4
1.4
—
365.56
—
0
36
7
50
1.43
0.46
2.0
2.1
—
0.00
estimate
—
0
18
14
104
1.40
0.46
1.3
1.5
—
—
—
0
0
33
280
1.25
0.45
3.6
3.3
—
—
—
0
0
88
925
0.78
0.44
4.7
5.4
1.48
1.46
mmol/l
0.13
76
862
0
16
0.00
0.41
0.0
3.6
—
1.12
—
0
16
0
16
0.00
0.41
0.0
1.7
—
105.94
—
0
16
0
16
0.00
0.41
0.0
1.7
—
1.20
—
0
16
0
16
0.00
0.41
0.0
1.7
—
4.06
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
90
941
0.79
0.40
5.3
6.3
2.40
2.60
mmol/l
1.42
79
879
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
55
498
1.20
0.40
4.7
3.9
0.00
0.00
estimate
-0.00
11
90
13
98
1.37
0.39
1.5
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
35
306
1.21
0.36
2.7
3.1
29.73
250.76
e6/l
0.51
26
228
12
92
1.34
0.33
2.3
3.9
7.38
7.34
ph
—
6
62
43
387
1.18
0.32
5.2
3.8
0.00
0.01
estimate
0.49
11
74
38
421
0.85
0.29
1.7
2.0
1.14
1.32
mmol/l
1.18
31
369
74
700
1.17
0.28
4.5
4.0
14.49
14.96
pmol/l
0.75
65
642
17
141
1.24
0.28
1.9
1.6
—
—
—
0
0
52
480
1.15
0.27
2.0
2.1
86.77
95.31
pmol/l
0.61
27
240
8
67
1.21
0.27
1.8
1.4
—
—
—
0
0
44
404
1.15
0.25
4.3
3.6
6.20
6.19
ph
0.02
25
228
27
240
1.16
0.23
4.7
4.4
1.02
1.02
kg/l
0.97
20
159
12
145
0.81
0.22
1.1
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
11.90
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
48.50
—
0
10
0
10
0.00
0.21
0.0
1.3
—
7.97
—
0
10
0
10
0.00
0.21
0.0
1.2
—
2.85
—
0
10
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
5.87
—
0
10
0
10
0.00
0.21
0.0
1.6
—
3.18
—
0
5
0
10
0.00
0.21
0.0
1.2
—
0.37
—
0
10
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
27.92
—
0
12
0
12
0.00
0.21
0.0
1.5
—
310.95
—
0
12
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.49
—
0
8
6
51
1.19
0.20
2.5
2.4
—
—
—
0
0
37
341
1.13
0.19
3.2
3.9
11.50
122.94
e6/l
1.96
27
233
22
196
1.15
0.18
7.9
4.5
—
—
—
0
0
34
368
0.89
0.18
2.5
3.4
7.62
7.63
mmol/l
0.00
23
315
6
75
0.79
0.16
1.5
1.5
—
—
—
0
0
86
883
0.89
0.15
3.9
4.6
1.15
1.26
mmol/l
1.34
75
820
10
84
1.21
0.14
1.7
4.6
342.60
231.83
ng/l
—
10
75
34
361
0.92
0.12
3.1
4.2
3.19
9.67
mg/mmol
1.93
16
231
90
918
0.90
0.11
4.6
5.3
5.75
6.01
mmol/l
2.00
74
835
5
45
1.12
0.10
2.0
1.9
—
—
—
0
0
5
60
0.83
0.08
1.0
1.3
—
—
—
0
0
9
84
1.08
0.07
1.3
1.4
—
—
—
0
0
29
277
1.06
0.06
4.6
3.5
0.00
0.00
estimate
-0.00
11
70
34
352
0.95
0.05
2.6
3.5
24.68
62.16
mg/l
1.68
17
232
28
272
1.04
0.02
2.6
3.3
—
0.33
—
0
6
36
368
0.97
0.02
2.5
3.3
—
—
—
0
0
40
405
0.98
0.00
4.3
4.0
31.23
41.74
ng/l
0.42
30
291
18
181
0.99
0.00
1.5
1.7
1438.27
1173.60
nmol/l
0.40
11
136
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
11.18
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
82
0.97
-0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.92
-0.00
2.7
1.7
319.67
389.10
nmol/l
—
9
88
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
97.75
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
80.67
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
86.05
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
14.68
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
153.67
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
0.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_CHONDROSARCOMA – Chondrosarcoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).