No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519870 |
1. Apply sex-specific ruleNone |
519870 |
2. Check conditionsNone |
519870 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2167 |
4. Check minimum number of eventsNone |
2167 |
5. Include endpointsNone |
2167 |
6. Filter based on genotype QC (FinnGen only) |
2063 |
Control definitions (FinnGen only)
- Control exclude
- N14_UROLITHIASIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N20-N23
- Name in latin
- Urolithiasis viarum urinariarum inferiorum
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 15015 | 2873 | 11922 |
| Only index persons | 12181 | 2461 | 9720 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.28 | 0.08 | 0.33 |
| Only index persons | 0.31 | 0.09 | 0.37 |
| Median age at first event (years) | |||
| Whole population | 65.15 | 55.17 | 67.47 |
| Only index persons | 63.53 | 52.20 | 66.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2063 | 372 | 1691 |
| Unadjusted period prevalence (%) | 0.66 | 0.13 | 0.78 |
| Median age at first event (years) | 65.60 | 52.56 | 68.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2167
- Matched controls
- 21670
TimeCodeWAS
↥TODO / Current known limitations:
- Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
- Legend / how to read the glyphs.
- Proper column names.
- Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
- Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
- Download CSV not working.
- No filters and sorters.
- Limited amount of endpoints with TimeCodeWAS data.
- Cross-links to Risteys lab test pages for lab test codes.
N20.1 (45582395)
KAT00 (2001305749)
KBE12 (2001305847)
KBT00 (2001305887)
N20.2 (45534124)
N20.0 (45567830)
N21.0 (45582396)
KAE12 (2001305694)
KH1AA (2001306327)
N21.8 (45567831)
N21.1 (45577515)
N21.9 (45587238)
KBV02 (2001305891)
KBV12 (2001305895)
KCE00 (2001305951)
KCE02 (2001305953)
KDE12 (2001306046)
5941A (2000404672)
UKB02 (2001305907)
TKC10 (2001306019)
KDV10 (2001306084)
KDV12 (2001306085)
KH1BD (2001306330)
SMOKING-2-2-0 (2002330110)
SMOKING-2-3-0 (2002330113)
SMOKING-1-1-0 (2002330116)
50373000 (4177340)
60621009 (4245997)
N20.9 (45558141)
100906-7 (1761482)
1530 (2000100185)
7327 (2000101181)
59400 (2000303317)
59401 (2000303318)
6000A (2000404725)
XJH00 (2001305132)
JN3BD (2001305556)
KA1AE (2001305627)
KCD02 (2001305938)
TKC20 (2001306020)
UKD02 (2001306094)
KED22 (2001306138)
KED33 (2001306139)
KED52 (2001306140)
KED76 (2001306144)
KH1AD (2001306328)
KH1AE (2001306329)
R2130 (2001310196)
WX002 (2001310758)
WX320 (2001310799)
WX402 (2001310806)
WX404 (2001310807)
WX408 (2001310808)
WX700 (2001310817)
WX702 (2001310818)
ZXD10 (2001311387)
ZXE00 (2001311394)
ZXE10 (2001311401)
G04BE01 (21602646)
J01EA01 (21602931)
J01XE01 (21603058)
5811-5 (3000330)
1927-3 (3002032)
24419-4 (3002256)
882-1 (3003694)
14866-8 (3010566)
20454-5 (3014051)
1805-1 (3016417)
2021-4 (3021447)
2705-2 (3024354)
51484-4 (3030981)
58435-9 (40761536)
R10.3 (45534426)
R39.1 (45534441)
D41.4 (45537910)
N35.9 (45543870)
N99.1 (45543906)
N39.0 (45548665)
N13.3 (45553432)
R31 (45553726)
N32.0 (45567838)
C67.9 (45571528)
N30.0 (45601724)
N30.9 (45606488)
34 (38004474)
50554-5 (3029287)
51480-2 (3031040)
R33 (45587507)
UKC02 (2001306005)
22 (8756)
J01XX05 (21603065)
24357-6 (3037467)
21 (8717)
ER (9203)
J01MA02 (21603009)
630-4 (3026008)
SPAT1167 (2001700268)
890-4 (3001079)
U07 (2002001142)
N10 (45543856)
C61 (45547509)
J01EE02 (21602962)
44856007 (4261340)
KC1EE (2001305918)
93 (38004510)
Z43.5 (45556833)
T91.3 (45546766)
J01CA08 (21602827)
M03BX01 (21604115)
G04BD12 (43534790)
47525-1 (3049717)
30383-4 (3000850)
N40 (45563015)
J01MA12 (21603019)
30391-7 (3002582)
2695-5 (3026782)
C67.8 (45532924)
E21.09 (2000501463)
30405-5 (3018095)
OP (9202)
U08 (2002001143)
51486-9 (3029879)
OMOP5117446 (33004)
51483-6 (3030467)
ERIP (262)
87829-8 (36304419)
51485-1 (3030306)
JN3AD (2001305554)
53292-9 (3041096)
M01AB05 (21603945)
33052-2 (3045414)
N39.4 (45577525)
2 (38004447)
8140/3-C61.9 (44499685)
14749-6 (3013826)
R10.4 (45568113)
58434-2 (40761535)
13317-3 (3019902)
1 (38004446)
60026-2 (40763086)
U05 (2002001140)
50949-7 (3029937)
U01 (2002001137)
U13 (2002001144)
5802-4 (3021601)
2514-8 (3035350)
25428-4 (3009261)
U04 (2002001139)
2756-5 (3015736)
14637-3 (3010838)
KE1BE (2001306106)
1988-5 (3020460)
11524-6 (3013512)
G04BD08 (21602641)
N30 (45563012)
14631-6 (3006140)
62238-1 (40764999)
IP (9201)
G04CA02 (21602669)
U29 (2002001149)
14682-9 (3020564)
2951-2 (3019550)
N02AX02 (21604298)
TKC22 (2001306021)
N39.3 (45539046)
B02AA02 (21601036)
J01MA06 (21603013)
G04CA52 (21602673)
2823-3 (3023103)
58410-2 (40761511)
5810-7 (3019150)
34531-4 (3044640)
715-3 (3021589)
34534-8 (3044889)
U06 (2002001141)
6768-6 (3035995)
G04CA01 (21602668)
R30.0 (45592416)
26515-7 (3007461)
718-7 (3000963)
28539-5 (3035941)
26464-8 (3010813)
30428-7 (3024731)
26453-1 (3026361)
55429-5 (40758558)
20570-8 (3009542)
5794-3 (3011397)
19072-8 (3016431)
30385-9 (3002385)
OMOP4822461 (32036)
11 (38004456)
2075-0 (3014576)
J01MA01 (21603008)
39 (38004479)
600-7 (3023368)
E78.01 (2000501514)
U02 (2002001138)
1995-0 (3021347)
2857-1 (3013603)
ZXD05 (2001311386)
R35 (45539331)
751-8 (3013650)
261QX0200X (38004268)
2020-6 (3023024)
I10 (45591453)
JN4AD (2001310897)
77397-8 (46236098)
2745-8 (3009343)
BBA30 (2001300785)
WZC30 (2001310891)
28540-3 (3003338)
OMOP4822458 (581477)
106 (44777669)
14933-6 (3026493)
34714-6 (3032080)
90 (38004507)
N02AA05 (21604260)
251B00000X (38004193)
16 (38004461)
5894-1 (3033658)
J01CR02 (21602863)
L02AE02 (21603825)
5803-2 (3022621)
72720-6 (43055554)
Z2221 (2001311556)
N02BE01 (21604344)
WZC00 (2001310885)
10886-0 (3005013)
R02AX02 (1588667)
M01AE01 (21603967)
SPAT1262 (2001700363)
J01DB01 (21602870)
A12AA20 (21600872)
TPH04 (2001309597)
1742-6 (3006923)
Z09.0 (45576131)
OMOP4822462 (581458)
66121-5 (40768804)
24337-8 (3022313)
I48 (45596206)
12841-3 (3001784)
6598-7 (3019800)
10 (38004455)
J01CA04 (21602823)
1751-7 (3024561)
ZXE20 (2001311408)
19926-5 (3011505)
19870-5 (3020158)
20150-9 (3024653)
D11AX10 (21602350)
G04CB01 (21602675)
19875-4 (3001668)
20155-8 (3023550)
69970-2 (42868459)
69982-7 (42868471)
69983-5 (42868472)
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint N14_CALCULOWER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_CALCULOWER | 1.812 [1.52, 2.16] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 398 out of 1853 females with N14_CALCULOWER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_CALCULOWER | 1.241 [1.11, 1.38] | < 0.001 |
| Birth year | 0.98 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 2580 out of 8052 males with N14_CALCULOWER died.
Mortality risk
Mortality risk for people of age
years, who have N14_CALCULOWER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.133% | 0.16% |
| 5 | 0.89% | 1.114% |
| 10 | 2.155% | 2.884% |
| 15 | 4.038% | 5.312% |
| 20 | 6.862% | 8.746% |
Relationships between endpoints
↥Index endpoint: N14_CALCULOWER – Calculus of lower urinary tract
GWS hits: 1