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Congenital iodine-deficiency syndrome/hypothyroidism

DOID EFO Endpoint Browser PheWeb

E4_CONGEIOD

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E00, E03.0, E03.1
  • Hospital discharge: ICD-9 — 243
  • Hospital discharge: ICD-8 — 243
  • Cause of death: ICD-10 — E00, E03.0, E03.1
  • Cause of death: ICD-9 — 243
  • Cause of death: ICD-8 — 243

2 out of 7 registries used, show all original rules.

1267

4. Check minimum number of events

None

1267

5. Include endpoints

None

1267

6. Filter based on genotype QC (FinnGen only)

1123

Control definitions (FinnGen only)

Control exclude
E4_THYROID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11024 8810 2178
Only index persons 10110 8174 1936
Unadjusted period prevalence (%)
Whole population 0.21 0.25 0.06
Only index persons 0.26 0.30 0.07
Median age at first event (years)
Whole population 67.75 68.82 63.38
Only index persons 67.54 68.52 63.45

-FinnGen-

Key figures

All Female Male
Number of individuals 1123 906 217
Unadjusted period prevalence (%) 0.28 0.32 0.10
Median age at first event (years) 60.90 59.48 66.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1161
Matched controls
11610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T86
ICPC
Hypothyroidism/myxoedema
128.1
307.7
165
15
H03AA01
ATC
levothyroxine sodium; systemic
2501.6
307.7
1122
132
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
307.7
937
*
104
Kela drug reimbursment
Thyroid insufficiency
1999.5
307.7
475
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
984.5
307.7
834
30
E03
ICD-10 Finland
Other hypothyroidism
687.5
281.4
267
5
E03.89
ICD-10 Finland
Other specified hypothyroidism
455.7
256.7
248
7
E03.1
ICD-10 Finland
Congenital hypothyroidism without goitre
2568.8
211.0
198
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
67.9
160.4
88
14
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
126.4
119
*
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
35.7
76.0
48
14
H03BB01
ATC
carbimazole; oral
87.8
66.8
74
9
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
203.3
56.5
58
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
574.7
56.1
55
*
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
6.1
55.2
100
176
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
5.2
48.9
105
216
A10AB05
ATC
insulin aspart; parenteral
3.8
46.9
155
447
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.7
45.8
59
71
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.8
45.0
86
159
SPAT1254
SPAT
Administration of medicine
2.7
41.6
278
1211
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.3
41.2
55
69
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
40.9
39
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
+∞
40.9
39
*
T89
ICPC
Diabetes insulin dependent
5.3
39.5
83
167
A10AB01
ATC
insulin (human); parenteral
5.6
38.5
75
141
A10AE04
ATC
insulin glargine; parenteral
3.2
38.3
168
579
BAA60
NOMESCO Finland
Total thyroidectomy
389.7
38.3
38
*
A10AE05
ATC
insulin detemir; parenteral
4.1
36.7
106
276
J01MA12
ATC
levofloxacin; systemic
2.5
35.1
279
1310
C03CA01
ATC
furosemide; systemic
2.2
34.1
474
2812
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.3
34.0
330
1691
A10AB04
ATC
insulin lispro; parenteral
5.5
32.6
64
121
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
32.0
384
2140
H04AA01
ATC
glucagon; nasal, parenteral
7.0
31.2
48
71
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
9.5
31.0
37
40
A10AA01, ,
ATC
5.9
29.6
54
95
103
Kela drug reimbursment
Diabetes, insulin-treated
2.2
29.6
358
1991
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
+∞
29.3
28
*
SPAT1263
SPAT
Sampling
2.0
28.4
555
3662
A10AC01
ATC
insulin (human); parenteral
3.0
28.1
138
504
N03AX16
ATC
[U] pregabalin
2.1
27.7
326
1787
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
27.4
187
810
N05AH04
ATC
quetiapine; oral
2.3
27.3
250
1236
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.6
27.3
53
99
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
26.9
488
3121
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
26.8
351
1998
E66.00
ICD-10 Finland
Metabolic syndrome
3.7
26.7
88
251
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
26.4
398
2384
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
26.2
601
4148
A02BC02
ATC
pantoprazole; systemic
2.0
25.7
839
6504
SPAT1301
SPAT
No procedures
2.0
25.5
430
2672
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
25.3
272
1432
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
25.1
24
*
G47.3
ICD-10 Finland
Sleep apnoea
2.2
24.9
245
1244
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
24.9
297
1627
SPAT1262
SPAT
Handing over of treatment supplies
2.3
24.9
235
1174
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.8
24.7
79
221
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
43.9
24.7
30
7
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
24.2
249
1287
H02AB09
ATC
hydrocortisone; systemic
5.5
24.2
47
88
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
24.1
230
1152
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
24.1
307
1721
AA1AD
NOMESCO Finland
CT of head and brain
1.9
23.9
402
2484
N03AX09
ATC
lamotrigine; oral
3.7
23.7
76
213
N06AX11
ATC
mirtazapine; oral
1.9
23.6
450
2896
N05BA04
ATC
oxazepam; oral
2.0
23.3
370
2238
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
23.1
242
1257
A10AA02, ,
ATC
4.2
23.0
62
153
N05CF01
ATC
zopiclone; oral
1.9
23.0
434
2779
B03BA03
ATC
hydroxocobalamin; parenteral
3.2
22.6
94
311
N05AA02
ATC
levomepromazine; systemic
4.0
22.6
66
173
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
6.3
22.5
38
62
N06AX16
ATC
venlafaxine; oral
2.3
21.9
192
926
R06.0
ICD-10 Finland
Dyspnoea
1.9
21.8
366
2248
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.9
21.7
64
169
J01DB01
ATC
cefalexin; oral
2.2
21.5
973
8159
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
21.3
392
2476
N06AX21
ATC
duloxetine; oral
2.3
21.0
173
812
R42
ICD-10 Finland
Dizziness and giddiness
1.9
20.9
334
2013
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
20.7
482
3267
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
20.6
130
540
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
20.5
498
3418
T90
ICPC
Diabetes non-insulin dependent
2.0
20.2
295
1721
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
20.0
163
760
R53
ICD-10 Finland
Malaise and fatigue
1.9
20.0
357
2224
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.0
19.9
94
335
N06AB04
ATC
citalopram; systemic
2.0
19.9
277
1590
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
+∞
19.8
19
*
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
19.8
19
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
19.8
109
422
A06AD11
ATC
lactulose; oral
2.1
19.6
224
1196
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
18.1
19.6
30
17
N30.0
ICD-10 Finland
Acute cystitis
2.0
19.6
282
1635
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.6
19.6
66
191
ZXD05
NOMESCO Finland
Urgent procedure
1.8
19.6
384
2462
K29.4
ICD-10 Finland
Chronic atrophic gastritis
4.7
19.5
45
98
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
19.1
115
466
SPAT1229
SPAT
Assessment of need for aid
2.5
18.9
123
517
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
18.9
366
2332
XX9LA
NOMESCO Finland
Complementary kinetic X-ray examination without contrast
8.2
18.8
25
31
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
18.8
18
*
R4110, ,
SPAT
2.2
18.6
187
949
J01FF01
ATC
clindamycin; systemic
1.9
18.6
325
2003
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
193.0
18.6
19
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
18.6
108
430
A10AE06
ATC
insulin degludec; parenteral
3.9
18.5
55
146
E10
ICD-10 Finland
Type 1 diabetes mellitus
6.5
18.4
30
47
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
18.4
307
1865
R02
ICPC
Shortness of breath/dyspnoea
2.1
18.3
194
1005
R03AC02
ATC
salbutamol; inhalant
1.7
18.3
663
5041
N06AB03
ATC
fluoxetine; oral
2.2
18.3
166
809
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
25.5
18.3
25
10
N02BE01
ATC
paracetamol; systemic, rectal
2.5
18.2
1057
9327
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
18.2
741
5819
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
18.1
208
1110
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
18.1
244
1379
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
18.1
224
1229
H02AB06
ATC
prednisolone; systemic
1.7
18.0
565
4123
107
Kela drug reimbursment
Pernicious anaemia
5.1
17.9
38
77
SPAT1097
SPAT
Recording of ECG
2.1
17.8
196
1030
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
17.8
288
1730
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
17.8
478
3339
A28
ICPC
Limited function/disability NOS
1.9
17.7
282
1684
SPAT1216
SPAT
Assessment of functional ability
2.0
17.6
230
1285
24409
ICD-8 Finland
Myxoedema, (hypothyreosis) NUD
96.6
17.6
19
*
SPAT1255
SPAT
Intravenous administration of medicine
2.8
17.6
95
364
N03AE01
ATC
clonazepam; systemic
2.9
17.5
86
313
P29
ICPC
Psychological sympt/compl other
2.6
17.5
107
437
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.9
17.3
84
304
N06AA09
ATC
amitriptyline; systemic
2.3
17.2
141
658
B81
ICPC
Anaemia vit B12/folate deficiency
3.4
17.2
62
188
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
17.1
179
922
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
17.0
430
2942
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
16.9
232
1317
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.7
16.9
94
366
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.8
16.9
31
55
N03AX12
ATC
[U] gabapentin; oral
2.0
16.8
209
1146
N02AX02
ATC
tramadol; systemic, rectal
1.7
16.5
498
3569
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.1
16.5
71
240
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
16.4
345
2237
L28
ICPC
Limited function/disability (L)
1.8
16.3
281
1717
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.8
16.3
50
136
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
5.9
16.2
29
50
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
16.2
184
976
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
16.1
161
814
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
11.9
16.1
29
25
E06.3
ICD-10 Finland
Autoimmune thyroiditis
48.2
16.1
19
*
UJF32
NOMESCO Finland
Coloscopy
1.8
16.0
315
2000
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
13.8
16.0
27
20
N05AN01
ATC
lithium; oral
4.8
16.0
36
77
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
15.8
350
2299
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
15.8
253
1508
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
15.8
82
308
R11
ICD-10 Finland
Nausea and vomiting
2.2
15.7
142
689
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
15.7
124
569
24399
ICD-8 Finland
Cretinism of congenital origin
+∞
15.7
15
*
SPAT1104
SPAT
Monitoring of emergency patient
2.7
15.5
88
346
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
15.4
271
1661
N03AG01
ATC
valproic acid; systemic, rectal
2.7
15.4
86
335
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
15.3
468
3346
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
15.3
232
1358
A02BC05
ATC
esomeprazole; systemic
1.7
15.3
472
3385
K59.1
ICD-10 Finland
Functional diarrhoea
2.6
15.2
92
373
C10AA01
ATC
simvastatin; oral
1.7
15.1
486
3520
OAB50, ,
SPAT
2.4
15.1
106
462
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.5
15.0
37
85
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.1
15.0
146
730
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
14.9
62
205
R51.80
ICD-10 Finland
Headache
1.9
14.8
208
1186
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
14.7
340
2254
R60.0
ICD-10 Finland
Localized oedema
2.0
14.7
177
958
C07AB07
ATC
bisoprolol; oral
1.6
14.7
578
4393
R50.9
ICD-10 Finland
Fever, unspecified
2.0
14.6
189
1047
SPAT1153
SPAT
Removal of sutures
1.7
14.6
367
2486
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
14.6
14
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
14.6
145
731
C10AA05
ATC
atorvastatin; oral
1.6
14.5
474
3438
N06AB06
ATC
sertraline; oral
2.1
14.4
145
733
A10BA02
ATC
metformin; oral
1.7
14.4
329
2171
N02AA05
ATC
oxycodone; systemic
1.8
14.4
247
1501
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.8
14.3
75
283
G44.2
ICD-10 Finland
Tension-type headache
2.0
14.2
183
1012
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.7
14.1
75
285
ZX120
NOMESCO Finland
Intravenous
2.2
14.1
124
595
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
14.1
186
1038
E66.8
ICD-10 Finland
Other obesity
2.7
14.1
77
297
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
14.0
139
699
SPAT1240
SPAT
Therapeutic discussion
2.2
14.0
129
631
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.0
13.9
63
219
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
13.9
125
605
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
13.9
257
1595
A29
ICPC
General symptom/complaint other
1.9
13.8
187
1051
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
54.0
13.8
16
*
N30.9
ICD-10 Finland
Cystitis, unspecified
2.3
13.8
115
540
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
13.7
589
4544
E00.9
ICD-10 Finland
Congenital iodine-deficiency syndrome, unspecified
+∞
13.6
13
*
2430A
ICD-9 Finland
Congenital hypothyroidism[HYPOTHYREOSIS CONGENITA]
+∞
13.6
13
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
13.6
13
*
J01MA02
ATC
ciprofloxacin; systemic
1.6
13.6
442
3188
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
3.9
13.5
40
106
P03
ICPC
Feeling depressed
2.2
13.5
124
605
J01DA01
ATC
[U] cefalexin
1.6
13.5
703
5670
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
13.4
251
1560
SPAT1260
SPAT
Consultation of another employee
1.8
13.4
221
1323
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
13.4
128
635
N06AB10
ATC
escitalopram; oral
1.8
13.3
238
1460
E66.9
ICD-10 Finland
Obesity, unspecified
3.1
13.1
55
183
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.0
13.1
57
194
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
13.1
300
1974
A02BC01
ATC
omeprazole; systemic
1.7
13.1
334
2262
C09AA05
ATC
ramipril; oral
1.7
13.0
294
1926
N05AF03
ATC
chlorprothixene; systemic
3.9
12.9
37
96
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
12.8
252
1587
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
12.8
175
987
P01AB01
ATC
metronidazole; oral, rectal
1.6
12.8
473
3505
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
12.7
111
530
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
12.7
129
654
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
12.7
114
551
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.4
12.7
89
387
N05AH03
ATC
olanzapine; systemic
2.5
12.7
80
331
P99
ICPC
Psychological disorders other
3.4
12.7
45
135
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
5.5
12.6
24
44
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
12.6
179
1022
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.2
12.5
110
527
2449X
ICD-9 Finland
Acquired hypothyroidism, Unspecified hypothyroidism
+∞
12.5
12
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
12.5
12
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
12.5
231
1430
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
131.4
12.5
13
*
N06AX03
ATC
mianserin; oral
2.7
12.4
70
274
M01AH01
ATC
celecoxib; oral
1.8
12.4
224
1375
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
12.4
86
372
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
11.8
12.3
22
19
M79.7
ICD-10 Finland
Fibromyalgia
3.1
12.3
52
174
A46
ICD-10 Finland
Erysipelas
1.9
12.3
173
984
SPAT1251
SPAT
Organisation of medication
2.9
12.3
58
207
E0000UV, ,
ATC
1.6
12.2
492
3706
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.6
12.2
40
114
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
12.2
56
197
N05BA06
ATC
lorazepam; systemic, sublingual
2.5
12.1
78
326
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
12.0
120
604
H02AB04
ATC
methylprednisolone; systemic
1.9
12.0
177
1021
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
13.5
12.0
20
15
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.5
12.0
29
66
K02.1
ICD-10 Finland
Caries of dentine
1.5
11.9
626
4996
SPAT1281
SPAT
Other administrative function
2.2
11.9
100
471
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
11.9
180
1048
UKC02
NOMESCO Finland
Cystoscopy
1.9
11.9
166
942
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
11.8
122
623
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
11.8
417
3044
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
11.7
115
575
B01AB05
ATC
enoxaparin; parenteral
1.6
11.7
372
2645
N05CD07
ATC
temazepam; oral
1.9
11.7
159
894
SPAT1100
SPAT
Long-term monitoring of blood pressure
2.3
11.6
94
435
S97
ICPC
Chronic ulcer skin
2.3
11.6
90
409
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.6
11.6
67
266
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
11.6
136
727
N05BA01
ATC
diazepam; systemic, rectal
1.9
11.5
163
927
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.2
11.5
45
144
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
+∞
11.5
11
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
11.5
145
795
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
11.4
60
227
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
11.4
143
782
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
11.9
11.3
20
17
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
11.2
180
1065
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.0
11.2
132
707
H3600, E103,
ICD-10 Finland
10.2
11.0
21
21
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
43.7
10.9
13
*
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.5
10.9
37
108
M25.5
ICD-10 Finland
Pain in joint
1.6
10.9
381
2764
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
10.8
502
3874
N06AX12
ATC
bupropion; oral
2.4
10.7
76
332
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
10.7
126
673
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
10.7
120
630
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.3
10.7
83
378
SPAT1312
SPAT
General health counselling
1.6
10.6
358
2570
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
10.6
143
800
P28
ICPC
Limited function/disability (P)
5.3
10.6
21
40
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
10.6
139
771
RS221, ,
NOMESCO Finland
4.3
10.6
27
64
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.3
10.6
82
373
SPAT1325
SPAT
Vaccination
1.5
10.5
401
2958
A02BA02
ATC
ranitidine; systemic
1.7
10.5
232
1502
P06
ICPC
Sleep disturbance
1.9
10.5
146
826
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
10.5
101
502
A04
ICPC
Weakness/tiredness general
1.7
10.5
212
1341
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
10.4
93
448
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
10.4
10
*
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
10.4
10
*
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
+∞
10.4
10
*
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
10.4
10
*
N03AF02
ATC
oxcarbazepine; oral
3.0
10.4
45
153
N06AB05
ATC
paroxetine; oral
2.4
10.4
69
293
M79.6
ICD-10 Finland
Pain in limb
1.5
10.4
507
3942
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
10.4
211
1336
C07AB02
ATC
metoprolol; systemic
1.7
10.4
248
1639
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.0
10.3
115
603
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
10.3
98
485
L03
ICPC
Low back symptom/complaint
1.6
10.3
338
2411
A10BJ06
ATC
semaglutide; parenteral
2.6
10.2
61
246
C03DA01
ATC
spironolactone; oral
1.8
10.2
155
901
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
10.2
106
542
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.5
10.2
65
271
H3603, E103,
ICD-10 Finland
13.3
10.2
17
13
R32
ICD-10 Finland
Unspecified urinary incontinence
3.0
10.2
45
155
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
2.9
10.2
47
166
N06AX26
ATC
vortioxetine; oral
2.2
10.1
87
413
A05
ICPC
Feeling ill
2.2
10.1
85
400
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
10.1
56
218
D11
ICPC
Diarrhoea
1.8
10.1
148
851
R03BA05
ATC
fluticasone; inhalant
1.7
10.1
215
1378
A10BK01
ATC
dapagliflozin; oral
2.2
10.1
88
421
D09
ICPC
Nausea
2.4
10.1
67
285
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
10.0
108
559
H25.8
ICD-10 Finland
Other senile cataract
1.8
10.0
159
937
M54.5
ICD-10 Finland
Low back pain
1.5
9.9
413
3096
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.7
9.9
51
191
SPAT1310
SPAT
Counselling related to known health issue
1.5
9.9
354
2570
AN1
HP
Coronary angiography
1.9
9.8
128
708
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
9.8
577
4643
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
9.8
126
695
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
9.7
158
937
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.7
9.7
52
199
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
9.7
117
631
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.9
9.7
46
165
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
9.7
148
862
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
9.7
54
211
106
Kela drug reimbursment
Hypoparathyroidism
55.5
9.7
11
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.6
473
3666
A11CC03
ATC
alfacalcidol; systemic
3.7
9.6
30
83
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.6
9.6
54
212
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.6
273
1880
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
9.5
204
1307
J01EA01
ATC
trimethoprim; systemic
1.5
9.5
362
2659
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.0
9.5
112
599
XF402
NOMESCO Finland
ECG with work load test
1.9
9.5
116
628
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
9.5
87
424
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.6
9.5
54
213
E000001, ,
ATC
1.6
9.5
229
1514
K77
ICPC
Heart failure
3.1
9.5
39
129
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
7.6
9.4
21
28
R52.9
ICD-10 Finland
Pain, unspecified
1.9
9.4
121
666
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.1
9.4
92
460
MAA00
NOMESCO Finland
Amniocentesis
3.6
9.4
31
89
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.6
9.4
31
89
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
9.4
9
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.0
9.4
105
552
N05AH02
ATC
clozapine; systemic
4.6
9.3
22
49
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.6
9.3
22
49
Z01.2
ICD-10 Finland
Dental examination
1.5
9.3
498
3918
F32.8
ICD-10 Finland
Other depressive episodes
4.1
9.3
25
62
160
Kela drug reimbursment
exenatide
3.6
9.3
30
85
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.4
9.2
65
284
SPAT1252
SPAT
Overall medication plan or its review
2.1
9.2
89
443
M04AA01
ATC
allopurinol; systemic
1.8
9.2
140
814
WVA30, ,
SPAT
2.2
9.2
78
369
WX722
NOMESCO Finland
PEEP
2.6
9.2
52
205
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
9.1
269
1863
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.5
9.1
58
242
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.0
9.1
25
63
D07AC01
ATC
betamethasone; topical
1.5
9.0
387
2907
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.1
9.0
92
467
TK800
NOMESCO Finland
Hemodialysis
3.9
9.0
26
68
C08CA01
ATC
amlodipine; oral
1.5
9.0
446
3451
F60.8
ICD-10 Finland
Other specific personality disorders
18.8
8.9
13
7
Z2445
NOMESCO Finland
Psychologist
2.8
8.9
45
167
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
4.4
8.9
22
51
A02BC03
ATC
lansoprazole; oral
1.5
8.9
325
2362
C07AA05
ATC
propranolol; systemic
1.6
8.9
211
1388
Z25.1
ICD-10 Finland
Need for immunization against influenza
2.3
8.9
67
302
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
4.7
8.8
20
43
Z00.8
ICD-10 Finland
Other general examinations
2.0
8.8
98
513
N05AC02
ATC
thioridazine; oral
3.6
8.8
29
83
N05AX08
ATC
risperidone; systemic
1.9
8.8
117
651
K90
ICPC
Stroke/cerebrovascular accident
2.8
8.8
42
151
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
4.1
8.8
24
60
R5110, ,
SPAT
1.9
8.8
119
667
R05
ICPC
Cough
1.5
8.8
292
2078
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.9
8.8
115
638
J01AA02
ATC
doxycycline; systemic
1.5
8.7
856
7534
XF404
NOMESCO Finland
Ambulatory ECG
2.0
8.7
103
551
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.9
8.7
25
65
WX882
NOMESCO Finland
High dependency care
2.9
8.7
40
141
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.7
8.7
182
1158
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
8.7
261
1815
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.3
8.7
32
99
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.7
8.6
163
1008
A10BJ05
ATC
dulaglutide; parenteral
3.8
8.6
26
70
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
8.6
240
1639
SPAT1285
SPAT
Provision of consultation response
2.3
8.6
64
287
UJD02
NOMESCO Finland
Gastroscopy
2.3
8.6
61
268
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
8.5
71
333
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.7
8.5
160
989
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
27.7
8.5
11
*
WYA20
NOMESCO Finland
Home visit
3.1
8.5
35
116
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
8.5
122
697
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.4
8.5
56
238
RJ630, ,
NOMESCO Finland
90.7
8.4
9
*
A03
ICPC
Fever
1.7
8.4
185
1192
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.3
8.4
60
264
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
3.3
8.4
31
96
A10BH02
ATC
vildagliptin; oral
3.4
8.4
30
91
C01DA14
ATC
isosorbide mononitrate; oral
1.6
8.4
193
1258
F61.0
ICD-10 Finland
Mixed personality disorders
4.7
8.4
19
41
A12AA04
ATC
calcium carbonate; oral
4.7
8.4
19
41
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
1.9
8.4
102
552
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
8.4
55
233
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.4
771
6670
IHZ04, ,
SPAT
4.0
8.4
23
58
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
8.4
41
150
ZXA00
NOMESCO Finland
Right side
1.5
8.4
299
2158
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
8.3
45
173
N05BA12
ATC
alprazolam; oral
1.9
8.3
115
648
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.2
8.3
68
317
H02AB07
ATC
prednisone; oral
1.7
8.3
161
1003
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
10.8
8.3
15
14
N03AX14
ATC
levetiracetam; systemic
3.0
8.3
36
123
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
8.3
247
1713
J01CA04
ATC
amoxicillin; systemic
1.5
8.3
902
8061
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
8.2
174
1109
T82
ICPC
Obesity
2.6
8.2
48
192
SPAT1360
SPAT
Extensive global examination
2.0
8.2
85
434
EBA00
NOMESCO Finland
Extraction of tooth
1.5
8.2
384
2925
P76
ICPC
Depressive disorder
2.1
8.2
75
366
S06.0
ICD-10 Finland
Concussion
1.8
8.2
134
796
R39.1
ICD-10 Finland
Other difficulties with micturition
3.0
8.2
36
124
J01CA08
ATC
pivmecillinam; oral
1.4
8.2
570
4676
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
8.1
73
354
N05AB03
ATC
perphenazine; systemic, rectal
2.7
8.1
44
170
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.7
8.0
25
69
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
8.0
280
2008
C02AC05
ATC
moxonidine; oral
2.4
8.0
55
238
A07AA02
ATC
nystatin; oral
2.1
8.0
79
397
N04BC05
ATC
pramipexole; oral
1.9
8.0
97
525
H36.01
ICD-10 Finland
Diabetic maculopathy
4.3
8.0
20
47
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.5
7.9
47
190
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
6.6
7.9
19
29
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
7.9
76
378
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
13.1
7.9
13
10
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
7.9
299
2181
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.2
7.9
31
100
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
2.8
7.9
38
138
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.2
7.8
62
285
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.0
7.8
80
407
K11.2
ICD-10 Finland
Sialoadenitis
2.7
7.8
40
150
X58
ICD-10 Finland
Exposure to other specified factors
1.7
7.8
153
956
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
7.8
85
443
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
7.8
324
2408
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
7.8
68
326
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.8
268
1916
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
7.8
204
1372
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.1
7.8
69
333
A10BH01
ATC
sitagliptin; oral
1.9
7.7
106
596
SPAT1234
SPAT
Support of social functional capacity
2.0
7.7
78
395
R13
ICD-10 Finland
Dysphagia
2.0
7.7
80
409
2504
FHL
Unilateral resection or enucleation
45.3
7.7
9
*
SPAT1266
SPAT
Separate instruction to prepare for procedure
2.8
7.7
37
134
SPAT1167
SPAT
Insertion of urinary catheter
2.7
7.7
41
157
-50
ICPC
Medication/prescr/renewal
2.5
7.7
49
205
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
7.7
162
1032
SGA01
NOMESCO Finland
Emergency treatment
1.7
7.7
159
1008
R96
ICPC
Asthma
1.8
7.7
118
688
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
3.8
7.6
23
62
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.0
7.6
21
53
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.6
759
6599
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
7.6
136
828
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.6
513
4166
A10BB12
ATC
glimepiride; oral
2.0
7.6
84
440
H66.9
ICD-10 Finland
Otitis media, unspecified
2.0
7.6
76
384
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
7.6
108
615
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.8
7.6
110
630
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.0
7.6
77
391
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.4
7.6
51
219
S18
ICPC
Laceration/cut
1.4
7.5
504
4083
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
7.5
97
535
I50.0
ICD-10 Finland
Congestive heart failure
1.9
7.5
102
572
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.5
569
4710
J02AC01
ATC
fluconazole; systemic
1.4
7.5
450
3576
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.1
7.5
30
98
A08
ICPC
Swelling
2.0
7.4
82
429
E06.9
ICD-10 Finland
Thyroiditis, unspecified
80.6
7.4
8
*
SPAT1211
SPAT
Application of soft bandage
1.8
7.4
106
605
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.2
7.4
62
293
L08
ICPC
Shoulder symptom/complaint
1.5
7.3
250
1780
R52.2
ICD-10 Finland
Other chronic pain
2.4
7.3
51
222
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.5
7.3
46
191
R06.5
ICD-10 Finland
Mouth breathing
2.0
7.3
75
382
SPAT1304
SPAT
Counselling and guidance related to ageing
1.9
7.3
100
562
F34.1
ICD-10 Finland
Dysthymia
2.5
7.3
43
173
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.3
703
6051
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.3
7.3
53
235
2506
FHL
Thyroidectomy
+∞
7.3
7
*
2448A
ICD-9 Finland
Acquired hypothyroidism, Other specified acquired hypothyroidism[HYPOTHYREOSIS POST THYREOIDITIDEM]
+∞
7.3
7
*
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
3.2
7.3
28
89
P72
ICPC
Schizophrenia
3.5
7.3
24
69
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.7
7.3
38
144
L16
ICPC
Ankle symptom/complaint
1.7
7.3
145
910
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.3
523
4284
RF120, ,
NOMESCO Finland
5.8
7.2
19
33
Z00.0
ICD-10 Finland
General medical examination
1.5
7.2
215
1486
D02AE01
ATC
carbamide; topical
2.0
7.2
75
384
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
7.2
80
420
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.2
7.2
59
276
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
2.1
7.2
67
330
RS142, ,
NOMESCO Finland
30.2
7.2
9
*
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
30.2
7.2
9
*
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
7.1
87
471
RJ210, ,
NOMESCO Finland
20.2
7.1
10
5
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.0
7.1
80
421
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
7.1
199
1357
P73
ICPC
Affective psychosis
12.1
7.1
12
10
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.6
7.1
39
152
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.6
7.1
39
152
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.8
7.1
35
129
P01
ICPC
Feeling anxious/nervous/tense
1.7
7.1
132
814
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
10.1
7.0
13
13
C10AX09
ATC
ezetimibe; oral
1.6
7.0
160
1038
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
7.0
257
1856
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.7
7.0
132
815
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
7.0
100
570
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.3
7.0
26
81
N04AA02
ATC
biperiden; systemic
3.3
7.0
25
76
R01AD09
ATC
mometasone; nasal
1.4
6.9
469
3791
SPAT1284
SPAT
Extensive health certificate
2.9
6.9
31
108
C09CA06
ATC
candesartan; oral
1.5
6.9
258
1869
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
6.9
76
397
H02AA02
ATC
fludrocortisone; oral
5.5
6.9
19
35
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
5.9
6.9
18
31
C01BD01
ATC
amiodarone; systemic
3.1
6.9
28
92
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
4.0
6.9
19
48
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.0
6.9
68
342
R81
ICPC
Pneumonia
2.4
6.9
46
197
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
6.9
116
695
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
3.5
6.9
23
67
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.6
6.8
37
143
M01AX17
ATC
nimesulide; oral
1.5
6.8
260
1892
Z3231
NOMESCO Finland
Registered nurse
1.5
6.8
293
2183
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.8
307
2309
M03BX02
ATC
tizanidine; oral
1.4
6.8
630
5362
IGY02, ,
SPAT
4.3
6.8
17
40
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.2
6.7
57
270
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
6.7
98
562
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.5
6.7
266
1949
R55
ICD-10 Finland
Syncope and collapse
1.7
6.7
139
880
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
6.7
156
1017
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.7
414
3291
N02BF01
ATC
gabapentin; oral
1.7
6.7
120
731
WZC30
NOMESCO Finland
Teaching
1.6
6.7
163
1075
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
6.7
67
339
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
6.7
202
1400
RK112, ,
NOMESCO Finland
22.7
6.7
9
*
M54.6
ICD-10 Finland
Pain in thoracic spine
1.9
6.7
87
482
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.6
6.7
184
1250
R4120, ,
SPAT
3.8
6.7
20
54
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
4.0
6.6
18
45
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.9
6.6
14
18
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.8
6.6
31
111
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.1
6.6
26
84
P25
ICPC
Phase of life problem adult
2.3
6.6
47
207
J01MA14
ATC
moxifloxacin; systemic
1.8
6.6
97
558
CKC12
NOMESCO Finland
Photocoagulation of retina
2.4
6.5
43
183
I95.1
ICD-10 Finland
Orthostatic hypotension
2.2
6.5
56
267
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.8
6.5
91
516
A03FA02
ATC
cisapride; oral, rectal
1.8
6.5
94
539
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.5
408
3251
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
2.4
6.5
43
184
SPAT1359
SPAT
Use of symptom diary
2.9
6.5
30
107
SFA20
NOMESCO Finland
Two-surface restoration
1.4
6.4
586
4953
C03AA03
ATC
hydrochlorothiazide; oral
1.7
6.4
112
677
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
70.2
6.4
7
*
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
6.4
67
344
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
7.4
6.4
14
19
M10.0
ICD-10 Finland
Idiopathic gout
2.6
6.4
36
142
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
14.4
6.4
10
7
R06AE07
ATC
cetirizine; oral
1.4
6.4
468
3820
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.8
6.4
19
51
R07.2
ICD-10 Finland
Precordial pain
3.1
6.4
26
86
205
Kela drug reimbursment
Chronic hypertension
1.4
6.4
296
2235
R05
ICD-10 Finland
Cough
1.5
6.3
230
1655
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.3
6.3
47
211
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
6.3
76
410
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
6.3
85
476
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.8
6.3
31
114
E78.29
ICD-10 Finland
Other mixed hyperlipidaemia
6.0
6.3
16
27
A10BD07
ATC
metformin and sitagliptin; systemic
2.4
6.3
43
186
M48.0
ICD-10 Finland
Spinal stenosis
1.6
6.3
143
927
R04
ICPC
Breathing problem other
2.3
6.3
45
199
ACC51
NOMESCO Finland
Release of median nerve
1.8
6.3
85
477
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
18.1
6.3
9
5
WZC00, ,
SPAT
1.6
6.3
155
1026
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
6.3
6
*
2440A
ICD-9 Finland
Acquired hypothyroidism, Postsurgical hypothyroidism
+∞
6.3
6
*
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
6.3
6
*
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
6.3
6
*
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
+∞
6.3
6
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
6.3
6
*
RT422, ,
NOMESCO Finland
+∞
6.3
6
*
E00.0
ICD-10 Finland
Congenital iodine-deficiency syndrome, neurological type
+∞
6.3
6
*
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
6.3
6
*
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
6.2
30
109
N05AD01
ATC
haloperidol; systemic
2.5
6.2
38
156
A11CC02
ATC
dihydrotachysterol; oral
26.8
6.2
8
*
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.1
6.2
25
82
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.1
6.2
25
82
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.1
6.2
25
82
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.3
6.2
45
200
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
6.2
127
802
B01AC04
ATC
clopidogrel; oral
1.6
6.2
173
1177
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
6.2
99
584
R07.3
ICD-10 Finland
Other chest pain
1.7
6.2
119
739
A10BG03
ATC
pioglitazone; oral
2.8
6.2
29
104
V03AE01
ATC
polystyrene sulfonate; oral
4.0
6.2
17
43
ZXA05
NOMESCO Finland
Left side
1.4
6.2
266
1979
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
5.4
6.2
17
32
A10BJ02
ATC
liraglutide; parenteral
2.6
6.2
34
133
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.2
262
1944
L04AD01
ATC
ciclosporin; systemic
3.3
6.2
22
67
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.9
6.2
76
414
K10.3
ICD-10 Finland
Alveolitis of jaws
2.2
6.2
51
240
XKD00
NOMESCO Finland
Uroflowmetry
1.7
6.2
103
616
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.1
6.1
25
83
XG466
NOMESCO Finland
Sleep oxymetry
2.8
6.1
29
105
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.7
6.1
117
727
Z2446
NOMESCO Finland
Social worker
1.9
6.1
77
423
QDB10, ,
SPAT
2.6
6.1
34
134
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
8.6
6.1
12
14
SFA30
NOMESCO Finland
Three-surface restoration
1.4
6.1
407
3269
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.4
6.1
41
177
K07
ICPC
Swollen ankles/oedema
2.0
6.0
64
331
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.9
6.0
72
388
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
3.0
6.0
26
89
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.2
6.0
17
33

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
215
311
8.26
146.25
3.5
1.4
4.23
4.48
pmol/l
2.17
191
264
1049
7558
5.02
67.61
11.4
2.8
16.22
14.53
pmol/l
68.11
982
6817
76
113
7.13
49.26
2.1
1.2
3.76
1.53
iu/l
1.63
40
26
697
4674
2.23
37.82
18.4
15.6
1.26
1.27
inr
0.29
626
3881
486
2874
2.19
35.60
2.6
2.4
3.19
2.90
mg/l
1.24
438
2472
811
5881
2.26
34.90
7.0
4.5
7.14
6.65
mmol/l
6.08
784
5539
478
2844
2.16
34.12
5.0
4.0
—
—
—
0
0
738
5230
2.13
32.59
9.5
6.3
1.22
1.22
mmol/l
0.45
633
4510
504
3143
2.07
30.99
2.5
2.1
153.65
196.62
u/l
1.19
481
2974
583
3841
2.04
30.71
6.1
4.0
37.16
50.18
ng/l
0.63
449
2760
502
3149
2.05
30.15
3.8
2.4
59.04
63.19
u/l
0.29
483
2901
678
4744
2.03
29.86
7.9
5.9
57.03
57.76
%
0.85
646
4510
327
1752
2.21
29.70
2.9
2.4
11.85
12.45
umol/l
0.82
309
1620
685
4825
2.02
29.43
8.1
6.0
27.69
27.43
%
0.24
649
4572
674
4746
2.00
28.68
8.3
6.1
8.74
8.71
%
0.12
632
4425
307
1624
2.21
28.64
2.8
2.4
2.40
2.32
g/l
1.60
281
1496
1065
9021
3.18
28.14
13.4
4.0
2.01
1.89
mu/l
1.02
1002
8274
164
659
2.73
27.98
4.1
3.9
5.18
5.17
kpa
0.07
159
632
671
4743
1.98
27.93
8.2
6.0
2.82
2.74
%
0.39
628
4416
670
4742
1.98
27.69
8.3
6.1
0.64
0.67
%
0.56
631
4409
161
645
2.74
27.62
4.0
3.9
7.41
7.42
ph
0.30
144
530
500
3206
1.98
27.55
4.2
3.2
1552.64
1475.84
ng/l
0.16
440
2751
336
1869
2.12
27.41
2.1
1.8
1202.61
1173.39
nmol/l
0.18
248
1385
673
4829
1.94
26.04
3.1
2.5
78.58
78.30
nmol/l
0.08
603
4340
654
4656
1.93
25.83
8.7
5.8
1.21
1.22
mmol/l
0.64
606
4259
701
5119
1.93
25.50
7.9
5.8
0.61
0.57
e9/l
1.61
619
4366
559
3793
1.91
25.42
4.2
3.5
—
—
—
0
0
701
5128
1.93
25.26
8.0
5.9
0.04
0.04
e9/l
0.81
616
4380
873
6887
2.08
25.20
8.3
5.2
2084.05
3155.79
e6/l
0.35
55
95
712
5240
1.93
25.13
7.9
5.9
1.88
1.87
e9/l
0.06
642
4596
367
2171
2.01
24.94
1.9
1.7
77597830.83
33240821.11
pmol/l
0.34
308
1793
719
5322
1.92
24.78
7.3
5.9
11.56
11.27
umol/l
0.14
691
5042
200
937
2.37
24.56
6.3
4.0
7.39
7.36
ph
2.68
148
644
673
4901
1.89
24.10
3.9
3.0
105.68
106.61
ug/l
0.05
630
4566
644
4651
1.86
23.39
2.6
2.1
98.58
95.82
pmol/l
0.67
353
2358
711
5307
1.88
23.15
8.1
6.1
0.19
0.18
e9/l
0.54
638
4593
191
907
2.32
22.63
2.1
1.8
367.40
382.62
nmol/l
0.45
176
830
503
3404
1.84
22.12
7.8
5.9
—
—
—
0
0
272
1501
2.06
22.04
2.9
2.4
20.11
21.70
%
1.30
255
1392
375
2316
1.91
21.96
4.0
2.6
7.25
6.85
e6/l
0.24
352
2082
637
4653
1.82
21.62
6.0
4.5
34.41
35.42
g/l
4.59
602
4345
495
3378
1.81
20.83
5.2
3.7
—
0.57
—
0
7
178
855
2.28
20.41
5.1
2.9
6.30
6.10
ph
1.64
130
583
481
3280
1.80
20.09
3.4
3.0
32.26
32.30
u/l
0.01
456
3098
282
1629
1.97
19.85
3.3
3.0
0.81
0.82
mmol/l
1.08
265
1529
482
3339
1.76
18.71
4.7
3.4
36.40
74.77
e6/l
0.93
402
2532
225
1226
2.04
18.57
2.7
2.6
1.93
1.80
%
0.95
198
1073
432
2909
1.77
18.44
5.3
3.6
0.02
0.05
estimate
0.40
105
898
237
1323
1.99
18.25
7.4
4.9
1.07
1.06
mmol/l
0.22
227
1215
370
2394
1.80
18.01
2.9
2.6
342.93
331.43
umol/l
0.98
314
2090
371
2405
1.80
17.93
1.5
1.4
1.48
1.62
u/ml
0.11
107
616
111
461
2.56
17.50
1.3
1.1
220.78
63.22
u/ml
3.58
59
146
533
3869
1.70
16.98
5.7
4.0
83.61
113.00
e6/l
0.59
417
2653
732
5786
1.72
16.93
12.0
8.9
4.25
4.10
e9/l
0.94
665
4988
908
7647
1.86
16.70
11.1
7.5
85.81
79.74
u/l
1.86
874
7207
212
1174
1.99
16.58
2.1
1.7
—
—
—
0
0
466
3280
1.70
16.53
4.7
3.2
6.13
6.86
mmol/l
4.30
397
2749
320
2037
1.79
16.16
3.8
3.0
509.93
512.68
mosm/kgh2o
0.09
292
1765
70
238
3.07
16.08
4.6
3.6
21.96
26.91
mg/l
0.64
57
166
697
5485
1.68
15.92
5.6
4.3
7.67
4.24
estimate
0.17
153
1158
234
1357
1.91
15.92
1.4
1.3
559.27
582.70
titre
0.06
55
296
468
3333
1.68
15.66
2.7
2.4
—
—
—
0
0
430
3004
1.69
15.42
5.2
4.3
0.00
0.01
estimate
1.34
131
1042
688
5423
1.66
15.37
5.7
4.2
0.00
0.00
estimate
0.80
145
1120
447
3157
1.68
15.36
5.5
3.9
13.23
8.81
mg/mmol
0.97
310
1912
616
4725
1.65
15.29
3.3
2.7
—
—
estimate
—
0
0
699
5537
1.66
15.27
5.8
4.3
0.00
0.29
estimate
0.54
147
1107
106
460
2.44
15.20
4.5
4.1
—
—
—
0
0
230
1359
1.86
14.66
1.2
1.2
—
—
—
0
0
434
3073
1.66
14.59
4.8
3.3
56.83
44.35
mg/l
0.57
309
1915
95
401
2.49
14.46
2.4
1.9
1.08
2.33
ug/l
0.91
79
347
315
2055
1.73
14.35
1.5
1.5
2.23
2.34
g/l
0.55
178
1228
437
3128
1.64
13.91
1.9
1.7
20.00
20.86
nmol/l
0.58
371
2598
762
6286
1.62
13.11
4.3
3.2
57.82
45.07
u/l
2.25
719
5861
203
1195
1.85
12.98
3.6
3.1
4.24
4.93
e9/l
0.89
163
1010
156
847
1.97
12.73
8.1
6.1
11.30
9.72
mmol/l
1.76
150
807
534
4095
1.56
12.27
5.9
4.2
0.03
0.06
estimate
0.57
110
916
83
361
2.40
11.84
4.6
4.5
24.73
24.83
mmol/l
0.13
77
335
224
1397
1.75
11.72
2.4
1.9
—
—
—
0
0
102
490
2.19
11.53
2.5
2.2
0.00
0.00
estimate
-0.00
26
147
268
1766
1.67
11.43
1.5
1.3
10.01
11.92
u/ml
0.19
105
657
347
2449
1.59
11.20
6.1
4.4
4.80
1.65
kg/l
0.39
267
1601
104
510
2.14
11.16
1.3
1.3
—
—
—
0
0
35
97
3.69
11.12
1.4
1.3
47.96
22.69
ng/l
1.12
35
97
154
877
1.87
10.84
2.6
2.7
64.66
66.60
g/l
2.22
135
804
193
1180
1.76
10.76
6.0
4.7
33.50
33.34
%
0.07
137
756
78
353
2.30
10.19
2.8
3.4
320.81
295.75
mg/l
0.13
36
136
491
3802
1.50
10.18
3.2
3.3
2.33
2.37
mmol/l
5.95
436
3425
279
1907
1.61
10.15
1.5
1.3
41.02
34.68
iu/ml
0.31
92
581
159
940
1.80
9.90
2.8
2.6
74.02
70.18
e9/l
0.56
129
681
323
2298
1.56
9.86
1.8
1.7
0.94
1.23
mg/l
2.53
253
1766
131
732
1.89
9.76
2.6
2.8
10.69
10.59
g/l
0.09
119
672
307
2175
1.56
9.50
4.9
4.6
—
—
—
0
0
551
4409
1.48
9.50
4.4
3.8
6.29
6.28
ph
0.11
333
2386
182
1134
1.72
9.42
2.5
2.7
7.66
7.58
umol/l
0.02
159
977
145
846
1.82
9.41
4.6
3.6
113.35
84.80
ng/l
1.52
119
721
31
89
3.55
9.39
3.1
2.2
—
—
—
0
0
57
233
2.52
9.32
1.3
1.6
523.19
522.11
mg/l
0.00
52
219
94
477
2.06
9.23
2.0
1.7
1.60
1.49
g/l
0.49
70
413
49
187
2.69
9.20
2.7
2.4
178.14
98.70
ug/min
0.55
32
104
163
993
1.75
9.13
2.5
2.1
0.00
0.00
estimate
-0.00
32
193
1047
9666
1.85
8.91
27.9
15.8
21.20
24.54
mg/l
3.21
951
7989
163
1000
1.73
8.90
2.8
2.2
0.20
0.21
g/l
0.47
152
945
1058
9811
1.88
8.71
32.2
18.7
139.13
139.55
mmol/l
5.05
1046
9600
1058
9822
1.87
8.52
32.6
18.8
3.98
3.96
mmol/l
0.84
1045
9586
12
6
20.19
8.48
4.8
1.2
6.64
48.32
ug/l
—
7
6
172
1092
1.68
8.26
4.1
3.7
7.38
7.38
ph
0.46
105
655
71
338
2.17
8.24
1.2
1.2
—
—
—
0
0
64
292
2.26
8.24
1.4
1.4
252.78
301.32
ug/g
1.24
40
164
59
261
2.33
8.16
2.2
2.2
124.43
125.87
g/l
0.16
50
209
975
8878
1.61
8.11
9.7
6.2
42.42
39.13
mmol/mol
14.51
902
8255
49
203
2.48
7.83
2.8
2.7
91.20
90.25
%
0.53
49
197
146
900
1.71
7.82
5.5
4.2
0.87
0.90
%
0.06
63
261
48
198
2.49
7.74
3.7
3.6
—
—
—
0
0
224
1541
1.56
7.73
2.1
2.0
29.98
29.30
s
1.04
217
1488
141
864
1.72
7.71
5.5
4.3
0.07
0.12
%
0.61
57
224
31
102
3.10
7.62
1.1
1.1
—
—
—
0
0
64
302
2.18
7.61
6.0
5.1
1.40
1.31
mmol/l
0.35
58
269
48
201
2.45
7.51
1.6
1.8
207.34
46.24
e6/l
0.36
38
145
31
103
3.06
7.50
2.4
2.6
1.67
1.21
g/24h
0.52
21
62
164
1054
1.65
7.50
4.0
3.7
1.88
1.82
mmol/l
0.07
143
893
35
125
2.86
7.48
1.4
1.2
—
—
—
0
0
29
94
3.14
7.32
1.6
2.0
—
—
—
0
0
165
1072
1.63
7.22
1.3
1.3
—
—
—
0
0
48
205
2.40
7.20
1.7
1.9
253.38
1621.15
e6/l
0.53
40
157
24
70
3.48
7.14
3.8
2.9
24.81
12.87
mg/l
0.31
19
49
173
1143
1.60
7.06
1.6
1.4
—
—
—
0
0
33
119
2.82
6.94
22.9
4.4
7.91
7.29
mmol/l
0.32
28
97
12
11
11.01
6.80
2.2
1.5
11.01
15.35
umol/l
0.91
12
11
36
144
2.55
6.23
3.0
3.1
0.97
1.78
%
0.98
30
131
128
809
1.65
6.23
2.8
2.5
5.51
6.14
ug/l
0.25
101
688
150
988
1.60
6.18
8.4
6.6
94.11
95.42
%
1.36
143
954
135
867
1.63
6.17
5.8
4.6
0.18
0.12
%
0.18
51
204
990
9181
1.53
6.15
6.7
5.0
6.23
5.89
mmol/l
7.30
920
8349
77
422
1.88
6.12
1.8
2.0
9.65
7.82
iu/ml
0.19
20
102
58
290
2.05
6.00
2.8
3.6
8.65
8.49
kpa
0.17
58
283
1072
10161
1.72
5.71
35.0
20.7
79.76
73.84
umol/l
3.64
1059
10021
98
592
1.72
5.66
1.7
1.9
1.20
1.61
g/l
1.45
90
540
131
854
1.60
5.64
1.3
1.2
—
—
—
0
0
13
20
6.56
5.56
1.4
1.4
4.81
8.08
mmol/l
1.49
13
20
131
857
1.60
5.56
4.7
4.1
0.64
0.70
%
0.13
57
241
41
185
2.26
5.50
1.7
1.8
—
—
—
0
0
39
173
2.30
5.44
4.6
3.8
2.74
2.76
mmol/l
0.01
32
117
163
1131
1.51
5.32
8.3
6.3
1.38
1.10
mmol/l
0.37
132
925
31
125
2.52
5.32
1.5
1.3
23.28
23.86
u/l
0.04
24
103
24
86
2.83
5.16
1.6
2.1
1434.05
1084.23
e6/l
0.54
19
74
28
109
2.61
5.16
4.3
5.9
12.61
12.45
mg/l
0.09
21
99
127
843
1.57
5.07
3.5
3.0
211.83
228.34
ng/l
0.18
116
774
944
8757
1.42
5.04
5.5
4.0
1.35
1.23
mmol/l
5.60
861
7942
15
32
4.73
5.00
4.1
1.2
25.75
46.66
u/ml
—
6
5
32
685
0.45
4.91
1.8
1.7
3.10
3.45
mmol/l
1.06
25
480
55
292
1.93
4.86
4.4
5.3
—
—
—
0
0
145
1003
1.51
4.81
1.6
1.5
—
—
—
0
0
14
30
4.71
4.69
1.4
1.3
—
—
—
0
0
64
362
1.81
4.66
4.4
3.5
192.81
81.66
mg/l
0.54
52
307
260
2016
1.37
4.63
5.5
3.7
370.58
310.13
ng/l
0.09
201
1566
382
3139
1.32
4.63
5.8
3.8
7.40
7.40
ph
0.07
309
2237
64
363
1.81
4.62
4.4
3.5
31.20
59.18
mg/l
1.48
52
307
24
92
2.64
4.58
4.0
3.7
—
—
—
0
0
177
1292
1.44
4.47
2.3
2.5
174.30
108.29
ug/g
0.95
144
1009
15
37
4.09
4.41
3.3
4.7
310.22
173.08
umol/l
—
9
26
135
940
1.49
4.34
3.1
3.3
4.70
4.41
kpa
1.06
129
910
350
2863
1.32
4.33
4.3
3.3
0.33
0.45
e6/l
1.18
279
2094
25
101
2.51
4.31
2.4
2.3
0.56
1.69
u/field
—
9
52
212
1610
1.39
4.27
3.7
3.1
3.88
3.48
e6/l
0.21
124
779
55
306
1.84
4.25
2.2
2.7
—
—
—
0
0
159
1149
1.44
4.23
8.5
6.3
5.09
5.09
kpa
0.02
153
1101
1052
10028
1.52
4.23
17.2
11.6
24.97
23.67
u/l
1.20
1028
9728
16
51
3.17
4.21
1.8
1.8
2.00
2.25
u/field
—
10
37
159
1150
1.44
4.21
8.5
6.3
11.15
12.15
kpa
2.04
152
1105
64
374
1.75
4.21
2.3
2.1
418.85
7101.30
u/l
3.44
24
162
312
2521
1.32
4.19
2.7
2.3
—
—
—
0
0
18
62
2.93
4.18
1.7
2.2
227.62
203.06
e6/l
0.18
13
52
18
62
2.93
4.18
1.7
2.1
649.83
477.83
e6/l
0.48
12
48
158
1147
1.44
4.11
8.4
6.4
7.41
7.42
ph
0.54
100
637
90
580
1.60
4.10
5.0
4.3
—
—
—
0
0
982
9258
1.39
4.03
6.4
4.8
4.52
4.67
mmol/l
4.70
910
8561
10
18
5.59
3.98
3.2
3.2
—
—
—
0
0
77
482
1.64
3.95
5.4
4.1
1.81
1.51
%
1.57
72
456
20
76
2.66
3.91
1.3
1.2
—
—
—
0
0
84
539
1.60
3.91
1.4
1.4
31.40
28.67
iu/l
0.30
77
464
51
286
1.82
3.87
1.3
1.3
1.42
3.35
u/ml
—
5
37
1084
10433
1.59
3.80
41.3
24.1
6.98
6.74
e9/l
2.79
1066
10163
1035
9868
1.45
3.79
25.5
14.3
—
—
—
0
0
56
326
1.75
3.76
4.9
3.3
30.49
8.17
ratio
0.47
35
176
11
24
4.62
3.75
1.7
2.0
—
—
—
0
0
975
9210
1.37
3.70
6.4
4.7
1.46
1.53
mmol/l
6.89
896
8465
1083
10429
1.57
3.69
41.2
24.0
90.78
91.10
fl
1.33
1076
10303
1083
10430
1.57
3.67
41.4
24.1
256.55
254.87
e9/l
0.36
1069
10205
8
12
6.70
3.67
3.9
2.2
—
—
—
0
0
1083
10432
1.57
3.65
41.3
24.1
4.34
4.38
e12/l
1.75
1065
10168
1083
10432
1.57
3.65
41.9
24.4
38.68
39.29
%
2.69
1075
10302
1083
10432
1.57
3.65
41.1
24.0
30.00
30.21
pg
2.94
1076
10304
994
9425
1.38
3.63
7.1
5.5
2.58
2.69
mmol/l
3.86
916
8690
14
40
3.53
3.61
1.1
1.1
72.71
75.04
mg/l
—
7
25
1083
10435
1.56
3.61
41.6
24.3
129.38
131.46
g/l
5.42
1075
10309
92
616
1.54
3.58
3.5
3.8
24.48
24.06
mmol/l
0.57
92
608
19
74
2.59
3.56
1.8
1.5
29.21
26.98
%
0.10
14
44
42
230
1.86
3.46
1.5
1.4
58.20
60.57
mmol/l
0.14
30
184
151
1123
1.40
3.43
3.6
4.1
25.09
20.57
ug/l
0.09
115
921
26
120
2.19
3.40
2.8
2.9
—
—
—
0
0
24
108
2.25
3.33
2.0
1.6
64.82
62.02
%
0.14
17
68
28
136
2.08
3.24
1.0
1.2
15.60
4629.79
iu/ml
—
5
28
92
631
1.50
3.22
2.6
2.4
11.93
19.99
au/ml
—
9
66
187
1458
1.34
3.16
1.8
1.6
—
—
—
0
0
457
3988
1.24
3.15
2.3
2.1
—
—
—
0
0
16
61
2.65
3.14
3.3
2.6
—
—
—
0
0
13
44
2.98
3.14
3.5
1.4
—
—
—
0
0
83
562
1.51
3.10
2.8
2.4
—
—
—
0
0
60
377
1.62
3.09
2.3
1.3
—
—
—
0
0
24
113
2.15
3.02
1.3
1.2
—
—
nmol/l
—
0
0
43
711
0.59
2.97
1.5
1.3
—
—
—
0
0
12
37
3.27
2.93
1.0
1.0
1187.50
1661.86
miu/ml
0.73
12
37
111
806
1.42
2.92
5.0
3.7
1.22
1.23
mmol/l
0.87
105
694
25
122
2.07
2.88
2.7
1.5
277.41
275.37
mosm/kgh2o
0.16
17
89
83
572
1.49
2.87
4.0
4.0
1.02
1.02
ratio
0.21
77
521
28
143
1.98
2.86
2.0
1.8
0.66
0.84
g/l
0.38
23
125
62
401
1.58
2.86
2.7
1.9
9.10
10.38
g/l
1.47
51
354
19
83
2.31
2.85
1.4
1.3
—
—
—
0
0
17
72
2.38
2.73
1.3
1.2
—
—
—
0
0
27
139
1.96
2.71
1.4
1.2
0.64
13.71
nmol/l
0.50
27
130
67
448
1.53
2.68
5.9
4.2
0.89
0.89
%
0.01
62
420
8
19
4.23
2.68
1.1
1.1
—
—
—
0
0
33
184
1.82
2.63
3.5
2.5
9.49
8.27
pmol/l
0.32
33
184
12
41
2.95
2.62
1.4
1.7
1.80
1.99
umol/l
0.40
12
35
9
26
3.48
2.48
1.0
1.1
114.00
142.04
mmol/24h
—
9
26
45
281
1.63
2.43
1.2
1.3
—
—
—
0
0
111
834
1.37
2.42
1.5
1.4
—
—
—
0
0
16
70
2.30
2.42
1.1
1.1
—
—
—
0
0
11
40
2.77
2.27
2.1
1.3
3.20
1.00
%
—
5
6
13
286
0.45
2.27
1.2
1.1
1.54
1.59
g/l
0.29
13
286
12
272
0.44
2.26
1.2
1.1
—
0.64
—
0
35
115
880
1.34
2.24
9.6
7.1
—
—
—
0
0
30
172
1.76
2.22
1.7
1.5
—
—
—
0
0
16
73
2.21
2.21
1.3
2.2
37.23
39.91
%
0.27
16
73
488
4399
1.19
2.21
16.9
11.1
0.00
0.00
e9/l
1.30
404
3562
10
35
2.87
2.21
1.0
1.7
23.50
28.77
%
—
10
35
19
94
2.04
2.16
2.2
2.2
—
—
—
0
0
6
14
4.30
2.15
1.5
1.0
—
—
—
0
0
38
236
1.63
2.13
1.5
1.4
—
—
—
0
0
20
102
1.98
2.11
3.6
2.0
—
—
—
0
0
349
3064
1.20
2.11
7.9
6.0
—
—
—
0
0
22
117
1.90
2.07
1.0
1.2
—
—
—
0
0
74
535
1.41
2.06
2.4
1.9
—
—
—
0
0
6
15
4.02
2.04
1.0
1.1
—
—
—
0
0
30
177
1.71
2.04
2.7
1.8
4.42
4.60
mmol/24h
0.09
25
157
41
265
1.57
1.97
1.7
1.6
14145.93
13622.50
e6/l
0.02
30
187
86
644
1.36
1.95
1.2
1.4
—
—
—
0
0
15
295
0.50
1.95
1.1
1.2
0.83
0.90
g/l
0.39
15
295
32
195
1.66
1.94
5.0
2.0
0.93
0.82
nmol/l
0.24
24
162
340
2998
1.19
1.94
4.7
3.3
0.10
0.05
0.21
20
105
8
27
2.98
1.94
1.1
1.6
73.13
67.81
nmol/24h
—
8
27
45
299
1.53
1.92
3.5
3.1
1.81
1.59
mmol/l
0.44
45
292
18
94
1.93
1.80
1.4
1.3
133649.23
161992.24
e6/l
0.07
13
59
7
23
3.06
1.80
1.4
1.8
—
—
—
0
0
120
961
1.28
1.72
4.3
2.2
35.01
38.26
u/l
0.27
96
794
5
13
3.86
1.71
1.6
1.0
4.97
6.55
mg/g
—
5
13
17
89
1.92
1.70
1.2
1.1
96.41
111.67
pmol/l
0.64
17
89
15
75
2.01
1.70
1.4
1.2
—
—
—
0
0
20
112
1.80
1.65
1.8
2.6
—
—
—
0
0
10
41
2.45
1.64
6.8
4.2
—
—
—
0
0
427
3880
1.16
1.64
2.1
1.9
1.41
1.31
mmol/l
1.25
371
3298
25
150
1.68
1.64
1.5
1.5
156.88
143.22
au/ml
—
8
43
199
1698
1.21
1.62
2.0
1.9
—
—
—
0
0
5
14
3.58
1.61
1.0
1.0
—
—
—
0
0
8
32
2.51
1.60
1.0
1.2
—
—
—
0
0
54
391
1.40
1.54
1.4
1.3
0.24
1.13
u/ml
—
5
28
13
64
2.04
1.54
2.2
1.7
104.00
86.72
ng/l
0.20
13
64
38
260
1.48
1.47
3.8
3.1
7.99
7.58
mmol/l
0.37
38
253
60
449
1.35
1.43
1.2
1.2
—
—
—
0
0
285
2538
1.16
1.41
4.8
3.8
88.81
90.81
%
0.59
276
2480
18
103
1.76
1.41
1.6
1.3
—
—
—
0
0
10
46
2.18
1.40
6.8
3.9
—
—
—
0
0
7
29
2.42
1.39
1.1
1.1
—
—
—
0
0
6
23
2.62
1.37
1.3
1.2
—
—
—
0
0
6
23
2.62
1.37
2.8
1.4
—
—
—
0
0
43
307
1.42
1.36
1.1
1.3
178.81
252.31
miu/ml
0.73
24
150
46
333
1.40
1.35
1.4
1.5
0.34
0.34
mg/l
0.00
18
137
16
90
1.79
1.33
1.5
1.1
—
—
—
0
0
18
107
1.69
1.26
1.4
1.3
42590.82
39121.66
e6/l
0.05
11
61
47
347
1.37
1.24
2.2
2.2
9.48
11.47
nmol/l
0.72
38
312
35
246
1.44
1.22
2.8
1.5
—
—
—
0
0
11
56
1.97
1.22
1.5
1.3
10.37
21.63
umol/l
2.25
11
50
21
132
1.60
1.21
2.0
2.9
—
—
—
0
0
19
117
1.63
1.18
1.2
1.1
—
—
—
0
0
21
133
1.59
1.18
4.0
1.8
—
—
—
0
0
47
352
1.35
1.15
1.1
1.1
—
—
—
0
0
32
226
1.43
1.11
3.1
1.8
—
—
—
0
0
5
21
2.39
1.09
1.4
1.3
—
—
—
0
0
5
21
2.39
1.09
1.0
1.1
—
—
—
0
0
5
21
2.39
1.09
1.2
1.6
—
—
—
0
0
8
41
1.96
1.09
3.5
1.6
—
—
—
0
0
11
59
1.87
1.07
1.5
2.0
7.56
7.94
mmol/l
0.17
11
59
7
33
2.13
1.05
1.3
1.3
—
—
—
0
0
18
274
0.65
1.01
1.6
1.6
42.17
63.19
ug/l
1.45
13
228
13
212
0.61
0.98
1.5
1.6
—
—
—
0
0
21
140
1.51
0.98
1.7
1.2
3.09
2.22
u/ml
0.30
11
58
41
310
1.33
0.98
3.8
4.8
1.93
1.46
mg/l
1.62
36
279
16
100
1.61
0.97
1.4
1.7
—
—
—
0
0
16
100
1.61
0.97
2.6
2.1
—
—
—
0
0
26
182
1.44
0.96
2.5
3.1
4.45
4.26
e9/l
0.16
26
182
37
276
1.35
0.96
1.9
1.7
—
—
—
0
0
11
62
1.78
0.94
1.0
1.0
708.00
636.94
ng/l
—
6
35
36
474
0.75
0.92
1.6
1.6
836.74
1000.61
mu/l
0.62
29
390
13
206
0.63
0.89
1.3
1.5
—
—
—
0
0
12
71
1.70
0.89
1.1
1.0
—
—
—
0
0
10
56
1.79
0.88
1.2
1.4
—
—
—
0
0
6
30
2.01
0.87
1.2
1.1
—
—
—
0
0
6
30
2.01
0.87
33.3
35.5
74.00
111.61
ug/l
—
6
23
36
273
1.33
0.86
4.4
3.6
1.02
0.84
nmol/l
1.80
29
228
20
137
1.47
0.84
1.2
1.1
—
—
—
0
0
24
172
1.40
0.81
1.2
1.4
253.00
263.93
u/ml
0.06
13
88
8
47
1.71
0.80
1.1
1.5
—
—
—
0
0
8
48
1.67
0.79
1.3
1.2
—
—
—
0
0
9
56
1.61
0.72
1.0
1.1
—
—
—
0
0
12
76
1.58
0.71
1.2
1.1
—
—
—
0
0
5
26
1.93
0.70
3.8
2.3
0.57
0.61
mmol/l
—
5
26
5
26
1.93
0.70
1.2
1.1
25.40
26.62
s
—
5
26
21
152
1.39
0.69
1.3
1.4
—
—
—
0
0
7
42
1.67
0.68
5.4
3.1
536.14
646.55
u/ml
—
7
42
36
285
1.27
0.67
1.6
1.4
199.16
287.17
pmol/l
0.33
36
280
38
305
1.25
0.64
2.9
1.5
—
—
—
0
0
20
146
1.38
0.64
1.3
1.2
—
—
—
0
0
29
225
1.30
0.63
1.3
1.2
35.48
51.08
u/ml
—
5
30
246
2286
1.10
0.63
3.0
2.7
2.45
2.47
mmol/l
0.78
211
2051
10
63
1.59
0.62
1.3
1.2
—
—
—
0
0
17
122
1.40
0.60
1.5
1.3
—
—
—
0
0
17
122
1.40
0.60
1.5
1.3
—
—
—
0
0
17
122
1.40
0.60
1.5
1.3
—
—
—
0
0
17
122
1.40
0.60
1.5
1.3
—
—
—
0
0
8
52
1.54
0.59
4.9
1.3
163.50
75.40
umol/l
—
8
52
0
22
0.00
0.59
0.0
5.4
—
64.64
—
0
13
100
887
1.14
0.59
1.3
1.5
—
—
—
0
0
35
282
1.25
0.58
2.9
1.6
—
—
—
0
0
89
784
1.15
0.58
6.0
4.2
—
—
—
0
0
147
1337
1.11
0.58
5.8
5.7
2.39
3.35
ug/l
0.70
127
1174
38
310
1.23
0.57
2.9
1.5
—
—
—
0
0
190
1755
1.10
0.56
3.7
3.0
0.78
1.63
e6/l
2.56
100
928
28
221
1.27
0.55
1.2
1.1
—
—
—
0
0
16
116
1.38
0.54
1.1
1.3
—
60.69
—
0
7
37
306
1.22
0.51
1.9
1.5
—
—
—
0
0
19
144
1.32
0.50
1.1
1.0
—
—
—
0
0
29
234
1.25
0.50
2.4
2.9
57.55
58.10
%
0.09
29
234
37
307
1.21
0.49
2.9
1.5
—
—
—
0
0
14
189
0.74
0.48
2.4
1.8
—
—
—
0
0
139
1278
1.10
0.47
1.3
1.3
—
—
—
0
0
20
156
1.29
0.45
1.8
2.1
0.82
0.90
%
0.26
15
106
7
50
1.40
0.45
1.0
1.0
—
—
—
0
0
14
104
1.35
0.43
1.4
1.2
—
—
—
0
0
12
87
1.38
0.42
1.3
1.1
2.63
3.85
u/ml
—
7
40
0
16
0.00
0.41
0.0
3.3
—
—
—
0
0
0
17
0.00
0.40
0.0
3.1
—
—
—
0
0
7
103
0.68
0.39
1.3
1.2
—
—
—
0
0
14
107
1.31
0.37
1.2
1.1
—
—
—
0
0
6
44
1.37
0.34
1.3
1.4
138.00
147.32
nmol/l
—
6
44
11
82
1.34
0.34
1.0
1.1
—
6.41
—
0
21
13
166
0.78
0.33
1.3
1.2
—
—
—
0
0
24
201
1.20
0.32
1.3
1.2
—
—
—
0
0
23
193
1.20
0.31
1.2
1.5
—
—
—
0
0
15
120
1.25
0.30
1.8
2.5
12.57
10.34
mmol/l
0.52
15
120
11
84
1.31
0.30
1.2
1.4
—
—
—
0
0
77
709
1.09
0.29
1.4
1.2
—
—
—
0
0
9
75
1.20
0.25
1.0
1.3
—
—
—
0
0
9
75
1.20
0.25
1.2
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.8
33.52
41.63
g/l
—
5
39
0
11
0.00
0.21
0.0
1.0
—
11.39
—
0
11
0
11
0.00
0.21
0.0
1.1
—
87.27
—
0
11
0
10
0.00
0.21
0.0
1.4
—
52.10
—
0
10
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
7.46
—
0
5
31
279
1.11
0.19
1.2
1.2
—
—
—
0
0
34
308
1.11
0.19
1.3
1.2
—
—
—
0
0
37
337
1.10
0.19
1.4
1.3
—
—
—
0
0
13
109
1.19
0.18
2.3
2.2
—
—
—
0
0
351
3432
1.03
0.18
3.7
3.1
—
—
—
0
0
21
185
1.14
0.18
1.1
1.1
2.31
7.58
u/ml
1.88
15
108
28
310
0.90
0.17
12.8
9.2
—
—
—
0
0
108
1031
1.05
0.17
1.7
1.7
—
—
—
0
0
9
81
1.11
0.15
1.2
1.2
—
—
—
0
0
32
294
1.09
0.15
3.5
3.6
0.81
3.61
index
1.14
21
138
11
127
0.86
0.12
1.0
1.0
0.10
0.25
u/ml
—
6
45
280
2750
1.02
0.11
1.5
1.5
—
—
—
0
0
798
8033
0.98
0.11
33.1
19.7
13.98
13.70
%
6.37
793
7925
16
178
0.90
0.11
1.2
1.1
2.25
0.94
u/ml
0.26
11
100
254
2583
0.98
0.10
4.9
4.1
0.00
0.13
1.02
15
39
12
106
1.13
0.09
1.4
1.3
—
—
—
0
0
12
134
0.89
0.08
1.2
1.1
—
—
—
0
0
12
108
1.11
0.07
1.1
1.1
—
—
—
0
0
9
102
0.88
0.06
1.8
2.1
13.03
13.21
%
—
9
102
23
219
1.05
0.04
1.3
1.1
1.85
2.72
u/ml
0.27
17
132
19
180
1.06
0.04
1.2
1.1
0.56
2.07
u/ml
1.07
12
94
17
161
1.06
0.03
1.2
1.1
—
—
—
0
0
17
161
1.06
0.03
1.2
1.1
—
—
—
0
0
40
411
0.97
0.03
3.0
2.9
194.62
1134.84
u/ml
1.37
32
358
77
782
0.98
0.03
3.0
3.2
0.56
0.85
ug/l
3.61
54
507
93
941
0.99
0.02
1.8
1.8
—
—
—
0
0
14
133
1.05
0.01
1.6
1.1
3.03
2.35
eliau/ml
—
6
54
100
1008
0.99
0.01
1.6
1.5
—
—
—
0
0
38
386
0.98
0.00
1.4
1.6
37.92
13.43
u/ml
—
6
78
18
178
1.01
0.00
1.1
1.2
—
—
—
0
0
38
381
1.00
0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
5.4
—
—
—
0
0
6
59
1.02
0.00
1.8
2.1
15.05
15.86
%
—
6
59
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
5
57
0.88
-0.00
2.8
3.6
0.80
0.75
index
—
5
57
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
233.00
—
0
5
10
100
1.00
-0.00
1.4
1.3
6.30
6.63
mmol/l
—
10
94
0
6
0.00
-0.00
0.0
1.5
—
0.15
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint E4_CONGEIOD and mortality.

Females

Parameter HR [95% CI] p-value
E4_CONGEIOD 1.653 [1.47, 1.86] < 0.001
Birth year 0.988 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 2652 out of 8009 females with E4_CONGEIOD died.

Males

Parameter HR [95% CI] p-value
E4_CONGEIOD 2.094 [1.67, 2.62] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 700 out of 1891 males with E4_CONGEIOD died.

Mortality risk

Mortality risk for people of age

years, who have E4_CONGEIOD.

N-year risk Females Males
1 0.098% 0.386%
5 0.745% 2.472%
10 1.882% 5.762%
15 3.749% 10.868%
20 6.505% 17.926%

Relationships between endpoints

↥

Index endpoint: E4_CONGEIOD – Congenital iodine-deficiency syndrome/hypothyroidism

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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